FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1579, 678 aa 1>>>pF1KA1579 678 - 678 aa - 678 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.8450+/-0.0004; mu= 15.8386+/- 0.025 mean_var=194.5666+/-42.111, 0's: 0 Z-trim(117.8): 93 B-trim: 767 in 1/54 Lambda= 0.091948 statistics sampled from 30097 (30192) to 30097 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.699), E-opt: 0.2 (0.354), width: 16 Scan time: 12.550 The best scores are: opt bits E(85289) NP_060681 (OMIM: 609953) ribonucleoprotein PTB-bin ( 678) 4504 610.6 6.1e-174 XP_011540008 (OMIM: 609953) PREDICTED: ribonucleop ( 473) 2654 365.0 3.7e-100 XP_006710801 (OMIM: 609953) PREDICTED: ribonucleop ( 691) 2654 365.2 4.7e-100 XP_011525973 (OMIM: 609950) PREDICTED: ribonucleop ( 731) 1356 193.0 3.3e-48 NP_597709 (OMIM: 609950) ribonucleoprotein PTB-bin ( 756) 1353 192.7 4.4e-48 XP_011539197 (OMIM: 168360) PREDICTED: ELAV-like p ( 379) 219 41.9 0.0055 XP_011539196 (OMIM: 168360) PREDICTED: ELAV-like p ( 379) 219 41.9 0.0055 XP_011539195 (OMIM: 168360) PREDICTED: ELAV-like p ( 380) 219 41.9 0.0055 NP_068771 (OMIM: 168360) ELAV-like protein 4 isofo ( 380) 219 41.9 0.0055 NP_001311137 (OMIM: 168360) ELAV-like protein 4 is ( 383) 219 41.9 0.0055 NP_001311142 (OMIM: 168360) ELAV-like protein 4 is ( 385) 219 41.9 0.0055 XP_006710474 (OMIM: 168360) PREDICTED: ELAV-like p ( 393) 219 41.9 0.0056 XP_011539191 (OMIM: 168360) PREDICTED: ELAV-like p ( 416) 219 41.9 0.0058 NP_001311138 (OMIM: 168360) ELAV-like protein 4 is ( 352) 217 41.6 0.0063 NP_001311144 (OMIM: 168360) ELAV-like protein 4 is ( 358) 217 41.6 0.0064 XP_016856028 (OMIM: 168360) PREDICTED: ELAV-like p ( 359) 217 41.6 0.0064 NP_001311143 (OMIM: 168360) ELAV-like protein 4 is ( 365) 217 41.6 0.0064 NP_001311141 (OMIM: 168360) ELAV-like protein 4 is ( 365) 217 41.6 0.0064 NP_001138248 (OMIM: 168360) ELAV-like protein 4 is ( 366) 217 41.6 0.0065 NP_001138246 (OMIM: 168360) ELAV-like protein 4 is ( 366) 217 41.6 0.0065 NP_001138249 (OMIM: 168360) ELAV-like protein 4 is ( 369) 217 41.6 0.0065 NP_001281277 (OMIM: 168360) ELAV-like protein 4 is ( 371) 217 41.6 0.0065 XP_016856027 (OMIM: 168360) PREDICTED: ELAV-like p ( 379) 217 41.6 0.0066 XP_011539192 (OMIM: 168360) PREDICTED: ELAV-like p ( 389) 217 41.6 0.0067 NP_001138247 (OMIM: 168360) ELAV-like protein 4 is ( 402) 217 41.6 0.0068 >>NP_060681 (OMIM: 609953) ribonucleoprotein PTB-binding (678 aa) initn: 4504 init1: 4504 opt: 4504 Z-score: 3243.7 bits: 610.6 E(85289): 6.1e-174 Smith-Waterman score: 4504; 100.0% identity (100.0% similar) in 678 aa overlap (1-678:1-678) 10 20 30 40 50 60 pF1KA1 MAAAAGDGGGEGGAGLGSAAGLGPGPGLRGQGPSAEAHEGAPDPMPAALHPEEVAARLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MAAAAGDGGGEGGAGLGSAAGLGPGPGLRGQGPSAEAHEGAPDPMPAALHPEEVAARLQR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 MQRELSNRRKILVKNLPQDSNCQEVHDLLKDYDLKYCYVDRNKRTAFVTLLNGEQAQNAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MQRELSNRRKILVKNLPQDSNCQEVHDLLKDYDLKYCYVDRNKRTAFVTLLNGEQAQNAI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 QMFHQYSFRGKDLIVQLQPTDALLCITNVPISFTSEEFEELVRAYGNIERCFLVYSEVTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 QMFHQYSFRGKDLIVQLQPTDALLCITNVPISFTSEEFEELVRAYGNIERCFLVYSEVTG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 HSKGYGFVEYMKKDFAAKARLELLGRQLGASALFAQWMDVNLLASELIHSKCLCIDKLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 HSKGYGFVEYMKKDFAAKARLELLGRQLGASALFAQWMDVNLLASELIHSKCLCIDKLPS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 DYRDSEELLQIFSSVHKPVFCQLAQDEGSYVGGFAVVEYSTAEQAEEVQQAADGMTIKGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 DYRDSEELLQIFSSVHKPVFCQLAQDEGSYVGGFAVVEYSTAEQAEEVQQAADGMTIKGS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 KVQVSFCAPGAPGRSTLAALIAAQRVMHSNQKGLLPEPNPVQIMKSLNNPAMLQVLLQPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 KVQVSFCAPGAPGRSTLAALIAAQRVMHSNQKGLLPEPNPVQIMKSLNNPAMLQVLLQPQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LCGRAVKPAVLGTPHSLPHLMNPSISPAFLHLNKAHQNLSHIPLAQQQLMKFENIHTNNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 LCGRAVKPAVLGTPHSLPHLMNPSISPAFLHLNKAHQNLSHIPLAQQQLMKFENIHTNNK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 PGLLGEPPAVVLQTALGIGSVLPLKKELGHHHGEAHKTSSLIPTQTTITAGMGMLPFFPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 PGLLGEPPAVVLQTALGIGSVLPLKKELGHHHGEAHKTSSLIPTQTTITAGMGMLPFFPN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 QHIAGQAGPGHSNTQEKQPATVGMAEGNFSGSQPYLQSFPNLAAGSLLVGHHKQQQSQPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 QHIAGQAGPGHSNTQEKQPATVGMAEGNFSGSQPYLQSFPNLAAGSLLVGHHKQQQSQPK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 GTEISSGAASKNQTSLLGEPPKEIRLSKNPYLNLASVLPSVCLSSPASKTTLHKTGIASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 GTEISSGAASKNQTSLLGEPPKEIRLSKNPYLNLASVLPSVCLSSPASKTTLHKTGIASS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 ILDAISQGSESQHALEKCIAYSPPFGDYAQVSSLRNEKRGSSYLISAPEGGSVECVDQHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 ILDAISQGSESQHALEKCIAYSPPFGDYAQVSSLRNEKRGSSYLISAPEGGSVECVDQHS 610 620 630 640 650 660 670 pF1KA1 QGTGAYYMETYLKKKRVY :::::::::::::::::: NP_060 QGTGAYYMETYLKKKRVY 670 >>XP_011540008 (OMIM: 609953) PREDICTED: ribonucleoprote (473 aa) initn: 3052 init1: 2654 opt: 2654 Z-score: 1919.2 bits: 365.0 E(85289): 3.7e-100 Smith-Waterman score: 3022; 97.0% identity (97.2% similar) in 471 aa overlap (1-458:1-471) 10 20 30 40 50 60 pF1KA1 MAAAAGDGGGEGGAGLGSAAGLGPGPGLRGQGPSAEAHEGAPDPMPAALHPEEVAARLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAAAAGDGGGEGGAGLGSAAGLGPGPGLRGQGPSAEAHEGAPDPMPAALHPEEVAARLQR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 MQRELSNRRKILVKNLPQDSNCQEVHDLLKDYDLKYCYVDRNKRTAFVTLLNGEQAQNAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQRELSNRRKILVKNLPQDSNCQEVHDLLKDYDLKYCYVDRNKRTAFVTLLNGEQAQNAI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 QMFHQYSFRGKDLIVQLQPTDALLCITNVPISFTSEEFEELVRAYGNIERCFLVYSEVTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QMFHQYSFRGKDLIVQLQPTDALLCITNVPISFTSEEFEELVRAYGNIERCFLVYSEVTG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 HSKGYGFVEYMKKDFAAKARLELLGRQLGASALFAQWMDVNLLASELIHSKCLCIDKLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSKGYGFVEYMKKDFAAKARLELLGRQLGASALFAQWMDVNLLASELIHSKCLCIDKLPS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 DYRDSEELLQIFSSVHKPVFCQLAQDEGSYVGGFAVVEYSTAEQAEEVQQAADGMTIKGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DYRDSEELLQIFSSVHKPVFCQLAQDEGSYVGGFAVVEYSTAEQAEEVQQAADGMTIKGS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 KVQVSFCAPGAPGRSTLAALIAAQRVMHSNQKGLLPEPNPVQIMKSLNNPAMLQVLLQPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVQVSFCAPGAPGRSTLAALIAAQRVMHSNQKGLLPEPNPVQIMKSLNNPAMLQVLLQPQ 310 320 330 340 350 360 370 380 390 400 pF1KA1 LCGRAVKPAVLGTPHSLPHLMNPSISPAFLHLNKAHQ-------------NLSHIPLAQQ ::::::::::::::::::::::::::::::::::::: :::::::::: XP_011 LCGRAVKPAVLGTPHSLPHLMNPSISPAFLHLNKAHQSSVMGNTSNLFLQNLSHIPLAQQ 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA1 QLMKFENIHTNNKPGLLGEPPAVVLQTALGIGSVLPLKKELGHHHGEAHKTSSLIPTQTT ::::::::::::::::::::::::::::::::::::::::::::::::::. XP_011 QLMKFENIHTNNKPGLLGEPPAVVLQTALGIGSVLPLKKELGHHHGEAHKSCL 430 440 450 460 470 470 480 490 500 510 520 pF1KA1 ITAGMGMLPFFPNQHIAGQAGPGHSNTQEKQPATVGMAEGNFSGSQPYLQSFPNLAAGSL >>XP_006710801 (OMIM: 609953) PREDICTED: ribonucleoprote (691 aa) initn: 2694 init1: 2654 opt: 2654 Z-score: 1917.3 bits: 365.2 E(85289): 4.7e-100 Smith-Waterman score: 4468; 98.1% identity (98.1% similar) in 691 aa overlap (1-678:1-691) 10 20 30 40 50 60 pF1KA1 MAAAAGDGGGEGGAGLGSAAGLGPGPGLRGQGPSAEAHEGAPDPMPAALHPEEVAARLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MAAAAGDGGGEGGAGLGSAAGLGPGPGLRGQGPSAEAHEGAPDPMPAALHPEEVAARLQR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 MQRELSNRRKILVKNLPQDSNCQEVHDLLKDYDLKYCYVDRNKRTAFVTLLNGEQAQNAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MQRELSNRRKILVKNLPQDSNCQEVHDLLKDYDLKYCYVDRNKRTAFVTLLNGEQAQNAI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 QMFHQYSFRGKDLIVQLQPTDALLCITNVPISFTSEEFEELVRAYGNIERCFLVYSEVTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QMFHQYSFRGKDLIVQLQPTDALLCITNVPISFTSEEFEELVRAYGNIERCFLVYSEVTG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 HSKGYGFVEYMKKDFAAKARLELLGRQLGASALFAQWMDVNLLASELIHSKCLCIDKLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HSKGYGFVEYMKKDFAAKARLELLGRQLGASALFAQWMDVNLLASELIHSKCLCIDKLPS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 DYRDSEELLQIFSSVHKPVFCQLAQDEGSYVGGFAVVEYSTAEQAEEVQQAADGMTIKGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DYRDSEELLQIFSSVHKPVFCQLAQDEGSYVGGFAVVEYSTAEQAEEVQQAADGMTIKGS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 KVQVSFCAPGAPGRSTLAALIAAQRVMHSNQKGLLPEPNPVQIMKSLNNPAMLQVLLQPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KVQVSFCAPGAPGRSTLAALIAAQRVMHSNQKGLLPEPNPVQIMKSLNNPAMLQVLLQPQ 310 320 330 340 350 360 370 380 390 400 pF1KA1 LCGRAVKPAVLGTPHSLPHLMNPSISPAFLHLNKAHQ-------------NLSHIPLAQQ ::::::::::::::::::::::::::::::::::::: :::::::::: XP_006 LCGRAVKPAVLGTPHSLPHLMNPSISPAFLHLNKAHQSSVMGNTSNLFLQNLSHIPLAQQ 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA1 QLMKFENIHTNNKPGLLGEPPAVVLQTALGIGSVLPLKKELGHHHGEAHKTSSLIPTQTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QLMKFENIHTNNKPGLLGEPPAVVLQTALGIGSVLPLKKELGHHHGEAHKTSSLIPTQTT 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA1 ITAGMGMLPFFPNQHIAGQAGPGHSNTQEKQPATVGMAEGNFSGSQPYLQSFPNLAAGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ITAGMGMLPFFPNQHIAGQAGPGHSNTQEKQPATVGMAEGNFSGSQPYLQSFPNLAAGSL 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA1 LVGHHKQQQSQPKGTEISSGAASKNQTSLLGEPPKEIRLSKNPYLNLASVLPSVCLSSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LVGHHKQQQSQPKGTEISSGAASKNQTSLLGEPPKEIRLSKNPYLNLASVLPSVCLSSPA 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA1 SKTTLHKTGIASSILDAISQGSESQHALEKCIAYSPPFGDYAQVSSLRNEKRGSSYLISA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SKTTLHKTGIASSILDAISQGSESQHALEKCIAYSPPFGDYAQVSSLRNEKRGSSYLISA 610 620 630 640 650 660 650 660 670 pF1KA1 PEGGSVECVDQHSQGTGAYYMETYLKKKRVY ::::::::::::::::::::::::::::::: XP_006 PEGGSVECVDQHSQGTGAYYMETYLKKKRVY 670 680 690 >>XP_011525973 (OMIM: 609950) PREDICTED: ribonucleoprote (731 aa) initn: 1532 init1: 1276 opt: 1356 Z-score: 986.5 bits: 193.0 E(85289): 3.3e-48 Smith-Waterman score: 1472; 42.5% identity (64.6% similar) in 656 aa overlap (22-664:30-624) 10 20 30 40 50 pF1KA1 MAAAAGDGGGEGGAGLGSAAGLGPGPGLRGQGPSAEAHEGAPDPMPAALHPE :.: : . .. .: :.. ::. : :: XP_011 MPLRPGSLVPEGAGFPKMAADVSVTHRPPLSPKSGAEVEAGDA-AERRAPEEELPPLDPE 10 20 30 40 50 60 70 80 90 100 110 pF1KA1 EVAARLQRMQRELSNRRKILVKNLPQDSNCQEVHDLLKDYDLKYCYVDRNKRTAFVTLLN :. ::.. .:.. ::::::...:: : . :::::::.::.::::.::. : :::::::: XP_011 EIRKRLEHTERQFRNRRKILIRGLPGDVTNQEVHDLLSDYELKYCFVDKYKGTAFVTLLN 60 70 80 90 100 110 120 130 140 150 160 170 pF1KA1 GEQAQNAIQMFHQYSFRGKDLIVQLQPTDALLCITNVPISFTSEEFEELVRAYGNIERCF ::::. ::. ::: .: ..: :::::::::::..:.: :.:...:::::: .:..:::: XP_011 GEQAEAAINAFHQSRLRERELSVQLQPTDALLCVANLPPSLTQQQFEELVRPFGSLERCF 120 130 140 150 160 170 180 190 200 210 220 230 pF1KA1 LVYSEVTGHSKGYGFVEYMKKDFAAKARLELLGRQLGASALFAQWMDVNLLASELIHSKC ::::: ::.::::::.:::::: ::.:. .:::. :: .:...: :.. :. :.::.: XP_011 LVYSERTGQSKGYGFAEYMKKDSAARAKSDLLGKPLGPRTLYVHWTDAGQLTPALLHSRC 180 190 200 210 220 230 240 250 260 270 280 290 pF1KA1 LCIDKLPSDYRDSEELLQIFSSVHKPVFCQLAQDEGSYVGGFAVVEYSTAEQAEEVQQAA ::.:.:: . : . : . .:.::.:.::::: . . . ::::.:: :::.:::.:: : XP_011 LCVDRLPPGFNDVDALCRALSAVHSPTFCQLACGQDGQLKGFAVLEYETAEMAEEAQQQA 240 250 260 270 280 290 300 310 320 330 340 350 pF1KA1 DGMTIKGSKVQVSFCAPGAPGRSTLAALIAAQRVMHSNQKGLLPEPNPVQIMKSLNNPAM ::... ::...::::::: :::: :::::::: . . :::::::: .:....:. : XP_011 DGLSLGGSHLRVSFCAPGPPGRSMLAALIAAQATALNRGKGLLPEPNILQLLNNLGPSAS 300 310 320 330 340 350 360 370 380 390 400 410 pF1KA1 LQVLLQPQLCGRAV-KPAVLGTPHSLPHLMNPSISPAFLHLNKAHQNLSHIPLAQQQLMK ::.::.: : : : : ..::.: ..: : .:..: :.:.: : : .: XP_011 LQLLLNPLLHGSAGGKQGLLGAPPAMPLLNGPALSTALLQLA-----------LQTQGQK 360 370 380 390 400 420 430 440 450 460 470 pF1KA1 FENIHTNNKPGLLGEPPAVVLQTALGIGSVLPLKKELGHHHGEAHKTSSLIPTQTTITAG :::.::. : .:: : . :: :: : :: XP_011 --------KPGILGDSPLGALQP--GAQPANPLLGEL--------------P------AG 410 420 430 480 490 500 510 520 pF1KA1 MGMLPFFPNQHIAGQAGPGHSNTQEKQPATVGMAEGN---FSGSQPYLQSFPNLAAGSLL :. : .: .. :. : :...: : :. .. . : : : : XP_011 GGLPPELPPRR--GKPPP-------LLPSVLGPAGGDREALGLGPPAAQLTPPPAP---- 440 450 460 470 480 530 540 550 560 570 580 pF1KA1 VGHHKQQQSQPKGTEISSGA-ASKNQTSLLGEPPKEIRLSKNPYLNLASVLPSVCLSSPA :: . : .: . .:: . .::::::::. :. :::::: :.::. :..:. XP_011 VG---LRGSGLRGLQKDSGPLPTPPGVSLLGEPPKDYRIPLNPYLNLHSLLPASNLAAPG 490 500 510 520 530 540 590 600 610 620 630 640 pF1KA1 SKTTLHKT-GIASSILDAISQGS-ESQHALEKCIAYSPP--FGDYAQVSSLRNEKRG--- . .. :. . : .:. .:.. . .: ... : .: : :. : XP_011 GGSSSSKAFQLKSRLLSPLSSARLPPEPGLSDSYSFDYPSDMGPRRLFSHPREPALGPHG 550 560 570 580 590 600 650 660 670 pF1KA1 -SSYLISAPEGGSVECVDQHSQGTGAYYMETYLKKKRVY : . .: : .: : . : :.: XP_011 PSRHKMSPPPSGFGE---RSSGGSGGGPLSHFYSGSPTSYFTSGLQAGLKQSHLSKAIGS 610 620 630 640 650 >>NP_597709 (OMIM: 609950) ribonucleoprotein PTB-binding (756 aa) initn: 1519 init1: 1276 opt: 1353 Z-score: 984.2 bits: 192.7 E(85289): 4.4e-48 Smith-Waterman score: 1448; 45.2% identity (67.0% similar) in 573 aa overlap (22-589:30-544) 10 20 30 40 50 pF1KA1 MAAAAGDGGGEGGAGLGSAAGLGPGPGLRGQGPSAEAHEGAPDPMPAALHPE :.: : . .. .: :.. ::. : :: NP_597 MPLRPGSLVPEGAGFPKMAADVSVTHRPPLSPKSGAEVEAGDA-AERRAPEEELPPLDPE 10 20 30 40 50 60 70 80 90 100 110 pF1KA1 EVAARLQRMQRELSNRRKILVKNLPQDSNCQEVHDLLKDYDLKYCYVDRNKRTAFVTLLN :. ::.. .:.. ::::::...:: : . :::::::.::.::::.::. : :::::::: NP_597 EIRKRLEHTERQFRNRRKILIRGLPGDVTNQEVHDLLSDYELKYCFVDKYKGTAFVTLLN 60 70 80 90 100 110 120 130 140 150 160 170 pF1KA1 GEQAQNAIQMFHQYSFRGKDLIVQLQPTDALLCITNVPISFTSEEFEELVRAYGNIERCF ::::. ::. ::: .: ..: :::::::::::..:.: :.:...:::::: .:..:::: NP_597 GEQAEAAINAFHQSRLRERELSVQLQPTDALLCVANLPPSLTQQQFEELVRPFGSLERCF 120 130 140 150 160 170 180 190 200 210 220 230 pF1KA1 LVYSEVTGHSKGYGFVEYMKKDFAAKARLELLGRQLGASALFAQWMDVNLLASELIHSKC ::::: ::.::::::.:::::: ::.:. .:::. :: .:...: :.. :. :.::.: NP_597 LVYSERTGQSKGYGFAEYMKKDSAARAKSDLLGKPLGPRTLYVHWTDAGQLTPALLHSRC 180 190 200 210 220 230 240 250 260 270 280 290 pF1KA1 LCIDKLPSDYRDSEELLQIFSSVHKPVFCQLAQDEGSYVGGFAVVEYSTAEQAEEVQQAA ::.:.:: . : . : . .:.::.:.::::: . . . ::::.:: :::.:::.:: : NP_597 LCVDRLPPGFNDVDALCRALSAVHSPTFCQLACGQDGQLKGFAVLEYETAEMAEEAQQQA 240 250 260 270 280 290 300 310 320 330 340 350 pF1KA1 DGMTIKGSKVQVSFCAPGAPGRSTLAALIAAQRVMHSNQKGLLPEPNPVQIMKSLNNPAM ::... ::...::::::: :::: :::::::: . . :::::::: .:....:. : NP_597 DGLSLGGSHLRVSFCAPGPPGRSMLAALIAAQATALNRGKGLLPEPNILQLLNNLGPSAS 300 310 320 330 340 350 360 370 380 390 400 410 pF1KA1 LQVLLQPQLCGRAV-KPAVLGTPHSLPHLMNPSISPAFLHLNKAHQNLSHIPLAQQQLMK ::.::.: : : : : ..::.: ..: : .:..: :.:.: : : .: NP_597 LQLLLNPLLHGSAGGKQGLLGAPPAMPLLNGPALSTALLQLA-----------LQTQGQK 360 370 380 390 400 420 430 440 450 460 470 pF1KA1 FENIHTNNKPGLLGEPPAVVLQTALGIGSVLPLKKELGHHHGEAHKTSSLIPTQTTITAG :::.::. : .:: : . :: :: : :: NP_597 --------KPGILGDSPLGALQP--GAQPANPLLGEL--------------P------AG 410 420 430 480 490 500 510 520 pF1KA1 MGMLPFFPNQHIAGQAGPGHSNTQEKQPATVGMAEGN---FSGSQPYLQSFPNLAAGSLL :. : .: .. :. : :...: : :. .. . : : : : .: NP_597 GGLPPELPPRR--GKPPP-------LLPSVLGPAGGDREALGLGPPAAQLTPPPAPVGL- 440 450 460 470 480 530 540 550 560 570 580 pF1KA1 VGHHKQQQSQPKGTEISSGA-ASKNQTSLLGEPPKEIRLSKNPYLNLASVLPSVCLSSPA . : .: . .:: . .::::::::. :. :::::: :.::. :.. NP_597 ------RGSGLRGLQKDSGPLPTPPGVSLLGEPPKDYRIPLNPYLNLHSLLPASNLAGKE 490 500 510 520 530 540 590 600 610 620 630 640 pF1KA1 SKTTLHKTGIASSILDAISQGSESQHALEKCIAYSPPFGDYAQVSSLRNEKRGSSYLISA .. NP_597 ARGWGGAGRSRRPAEGPPTNPPAPGGGSSSSKAFQLKSRLLSPLSSARLPPEPGLSDSYS 550 560 570 580 590 600 >>XP_011539197 (OMIM: 168360) PREDICTED: ELAV-like prote (379 aa) initn: 209 init1: 153 opt: 219 Z-score: 174.6 bits: 41.9 E(85289): 0.0055 Smith-Waterman score: 219; 25.4% identity (58.1% similar) in 248 aa overlap (144-383:47-289) 120 130 140 150 160 170 pF1KA1 EQAQNAIQMFHQYSFRGKDLIVQLQPTDALLCITNVPISFTSEEFEELVRAYGNIERCFL : .. .: ..:.:::. : . :.:: : : XP_011 SNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKL 20 30 40 50 60 70 180 190 200 210 220 230 pF1KA1 VYSEVTGHSKGYGFVEYMKKDFAAKARLELLGRQLGASALFAQWMDVNLLASELIHSKCL : ...::.: :::::.:. : :: : : .: .... ... . : :.. : XP_011 VRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPS---SASIRDANL 80 90 100 110 120 130 240 250 260 270 280 290 pF1KA1 CIDKLPSDYRDSEELLQIFSSVHKPVFCQLAQDEGSYVG-GFAVVEYSTAEQAEEVQQAA .. ::. . . .:: :.::. . . .. :. . :. : . .... .:::. .. XP_011 YVSGLPKTMTQ-KELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 140 150 160 170 180 190 300 310 320 330 340 350 pF1KA1 DGMTIKGSKVQVSFCAPGAPGRSTLAALIAAQRVMHSNQKGLLPEPNPVQIMK--SLNNP .:. .:. .. . :.... ::.. : . :.. : . .: .. .: : XP_011 NGQKPSGATEPITVKFANNPSQKSSQALLS-QLYQSPNRRYPGPLHHQAQRFRLDNLLNM 200 210 220 230 240 250 360 370 380 390 400 pF1KA1 AM-LQVLLQ----PQLCGRAVKPAVLGTPHSLPHLMNPSISPAFLHLNKAHQNLSHIPLA :. .. :.. :. : .: .. :: . : XP_011 AYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESV 260 270 280 290 300 310 410 420 430 440 450 460 pF1KA1 QQQLMKFENIHTNNKPGLLGEPPAVVLQTALGIGSVLPLKKELGHHHGEAHKTSSLIPTQ XP_011 LWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSF 320 330 340 350 360 370 >>XP_011539196 (OMIM: 168360) PREDICTED: ELAV-like prote (379 aa) initn: 209 init1: 153 opt: 219 Z-score: 174.6 bits: 41.9 E(85289): 0.0055 Smith-Waterman score: 219; 25.4% identity (58.1% similar) in 248 aa overlap (144-383:47-289) 120 130 140 150 160 170 pF1KA1 EQAQNAIQMFHQYSFRGKDLIVQLQPTDALLCITNVPISFTSEEFEELVRAYGNIERCFL : .. .: ..:.:::. : . :.:: : : XP_011 SNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKL 20 30 40 50 60 70 180 190 200 210 220 230 pF1KA1 VYSEVTGHSKGYGFVEYMKKDFAAKARLELLGRQLGASALFAQWMDVNLLASELIHSKCL : ...::.: :::::.:. : :: : : .: .... ... . : :.. : XP_011 VRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPS---SASIRDANL 80 90 100 110 120 130 240 250 260 270 280 290 pF1KA1 CIDKLPSDYRDSEELLQIFSSVHKPVFCQLAQDEGSYVG-GFAVVEYSTAEQAEEVQQAA .. ::. . . .:: :.::. . . .. :. . :. : . .... .:::. .. XP_011 YVSGLPKTMTQ-KELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 140 150 160 170 180 190 300 310 320 330 340 350 pF1KA1 DGMTIKGSKVQVSFCAPGAPGRSTLAALIAAQRVMHSNQKGLLPEPNPVQIMK--SLNNP .:. .:. .. . :.... ::.. : . :.. : . .: .. .: : XP_011 NGQKPSGATEPITVKFANNPSQKSSQALLS-QLYQSPNRRYPGPLHHQAQRFRLDNLLNM 200 210 220 230 240 250 360 370 380 390 400 pF1KA1 AM-LQVLLQ----PQLCGRAVKPAVLGTPHSLPHLMNPSISPAFLHLNKAHQNLSHIPLA :. .. :.. :. : .: .. :: . : XP_011 AYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESV 260 270 280 290 300 310 410 420 430 440 450 460 pF1KA1 QQQLMKFENIHTNNKPGLLGEPPAVVLQTALGIGSVLPLKKELGHHHGEAHKTSSLIPTQ XP_011 LWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSF 320 330 340 350 360 370 >>XP_011539195 (OMIM: 168360) PREDICTED: ELAV-like prote (380 aa) initn: 209 init1: 153 opt: 219 Z-score: 174.6 bits: 41.9 E(85289): 0.0055 Smith-Waterman score: 219; 25.4% identity (58.1% similar) in 248 aa overlap (144-383:48-290) 120 130 140 150 160 170 pF1KA1 EQAQNAIQMFHQYSFRGKDLIVQLQPTDALLCITNVPISFTSEEFEELVRAYGNIERCFL : .. .: ..:.:::. : . :.:: : : XP_011 SNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKL 20 30 40 50 60 70 180 190 200 210 220 230 pF1KA1 VYSEVTGHSKGYGFVEYMKKDFAAKARLELLGRQLGASALFAQWMDVNLLASELIHSKCL : ...::.: :::::.:. : :: : : .: .... ... . : :.. : XP_011 VRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPS---SASIRDANL 80 90 100 110 120 130 240 250 260 270 280 290 pF1KA1 CIDKLPSDYRDSEELLQIFSSVHKPVFCQLAQDEGSYVG-GFAVVEYSTAEQAEEVQQAA .. ::. . . .:: :.::. . . .. :. . :. : . .... .:::. .. XP_011 YVSGLPKTMTQ-KELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 140 150 160 170 180 190 300 310 320 330 340 350 pF1KA1 DGMTIKGSKVQVSFCAPGAPGRSTLAALIAAQRVMHSNQKGLLPEPNPVQIMK--SLNNP .:. .:. .. . :.... ::.. : . :.. : . .: .. .: : XP_011 NGQKPSGATEPITVKFANNPSQKSSQALLS-QLYQSPNRRYPGPLHHQAQRFRLDNLLNM 200 210 220 230 240 250 360 370 380 390 400 pF1KA1 AM-LQVLLQ----PQLCGRAVKPAVLGTPHSLPHLMNPSISPAFLHLNKAHQNLSHIPLA :. .. :.. :. : .: .. :: . : XP_011 AYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESV 260 270 280 290 300 310 410 420 430 440 450 460 pF1KA1 QQQLMKFENIHTNNKPGLLGEPPAVVLQTALGIGSVLPLKKELGHHHGEAHKTSSLIPTQ XP_011 LWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSF 320 330 340 350 360 370 >>NP_068771 (OMIM: 168360) ELAV-like protein 4 isoform 1 (380 aa) initn: 209 init1: 153 opt: 219 Z-score: 174.6 bits: 41.9 E(85289): 0.0055 Smith-Waterman score: 219; 25.4% identity (58.1% similar) in 248 aa overlap (144-383:48-290) 120 130 140 150 160 170 pF1KA1 EQAQNAIQMFHQYSFRGKDLIVQLQPTDALLCITNVPISFTSEEFEELVRAYGNIERCFL : .. .: ..:.:::. : . :.:: : : NP_068 SNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKL 20 30 40 50 60 70 180 190 200 210 220 230 pF1KA1 VYSEVTGHSKGYGFVEYMKKDFAAKARLELLGRQLGASALFAQWMDVNLLASELIHSKCL : ...::.: :::::.:. : :: : : .: .... ... . : :.. : NP_068 VRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPS---SASIRDANL 80 90 100 110 120 130 240 250 260 270 280 290 pF1KA1 CIDKLPSDYRDSEELLQIFSSVHKPVFCQLAQDEGSYVG-GFAVVEYSTAEQAEEVQQAA .. ::. . . .:: :.::. . . .. :. . :. : . .... .:::. .. NP_068 YVSGLPKTMTQ-KELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 140 150 160 170 180 190 300 310 320 330 340 350 pF1KA1 DGMTIKGSKVQVSFCAPGAPGRSTLAALIAAQRVMHSNQKGLLPEPNPVQIMK--SLNNP .:. .:. .. . :.... ::.. : . :.. : . .: .. .: : NP_068 NGQKPSGATEPITVKFANNPSQKSSQALLS-QLYQSPNRRYPGPLHHQAQRFRLDNLLNM 200 210 220 230 240 250 360 370 380 390 400 pF1KA1 AM-LQVLLQ----PQLCGRAVKPAVLGTPHSLPHLMNPSISPAFLHLNKAHQNLSHIPLA :. .. :.. :. : .: .. :: . : NP_068 AYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESV 260 270 280 290 300 310 410 420 430 440 450 460 pF1KA1 QQQLMKFENIHTNNKPGLLGEPPAVVLQTALGIGSVLPLKKELGHHHGEAHKTSSLIPTQ NP_068 LWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSF 320 330 340 350 360 370 >>NP_001311137 (OMIM: 168360) ELAV-like protein 4 isofor (383 aa) initn: 209 init1: 153 opt: 219 Z-score: 174.6 bits: 41.9 E(85289): 0.0055 Smith-Waterman score: 219; 25.4% identity (58.1% similar) in 248 aa overlap (144-383:51-293) 120 130 140 150 160 170 pF1KA1 EQAQNAIQMFHQYSFRGKDLIVQLQPTDALLCITNVPISFTSEEFEELVRAYGNIERCFL : .. .: ..:.:::. : . :.:: : : NP_001 SNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKL 30 40 50 60 70 80 180 190 200 210 220 230 pF1KA1 VYSEVTGHSKGYGFVEYMKKDFAAKARLELLGRQLGASALFAQWMDVNLLASELIHSKCL : ...::.: :::::.:. : :: : : .: .... ... . : :.. : NP_001 VRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPS---SASIRDANL 90 100 110 120 130 240 250 260 270 280 290 pF1KA1 CIDKLPSDYRDSEELLQIFSSVHKPVFCQLAQDEGSYVG-GFAVVEYSTAEQAEEVQQAA .. ::. . . .:: :.::. . . .. :. . :. : . .... .:::. .. NP_001 YVSGLPKTMTQ-KELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 140 150 160 170 180 190 300 310 320 330 340 350 pF1KA1 DGMTIKGSKVQVSFCAPGAPGRSTLAALIAAQRVMHSNQKGLLPEPNPVQIMK--SLNNP .:. .:. .. . :.... ::.. : . :.. : . .: .. .: : NP_001 NGQKPSGATEPITVKFANNPSQKSSQALLS-QLYQSPNRRYPGPLHHQAQRFRLDNLLNM 200 210 220 230 240 250 360 370 380 390 400 pF1KA1 AM-LQVLLQ----PQLCGRAVKPAVLGTPHSLPHLMNPSISPAFLHLNKAHQNLSHIPLA :. .. :.. :. : .: .. :: . : NP_001 AYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESV 260 270 280 290 300 310 410 420 430 440 450 460 pF1KA1 QQQLMKFENIHTNNKPGLLGEPPAVVLQTALGIGSVLPLKKELGHHHGEAHKTSSLIPTQ NP_001 LWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSF 320 330 340 350 360 370 678 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 01:39:15 2016 done: Fri Nov 4 01:39:17 2016 Total Scan time: 12.550 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]