Result of FASTA (omim) for
pF1KA1582
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1582, 1690 aa
1>>>pF1KA1582 1690 - 1690 aa - 1690 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.5232+/-0.000451; mu= -15.7679+/- 0.028
mean_var=415.7959+/-86.461, 0's: 0 Z-trim(122.0): 100 B-trim: 0 in 0/61
Lambda= 0.062898
statistics sampled from 39229 (39351) to 39229 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.461), width: 16
Scan time: 20.320
The best scores are: opt bits E(85289)
NP_061869 (OMIM: 610741) trinucleotide repeat-cont (1690) 11690 1076.5 0
XP_016880396 (OMIM: 610741) PREDICTED: trinucleoti (1932) 11690 1076.5 0
XP_006722063 (OMIM: 610741) PREDICTED: trinucleoti (1929) 11653 1073.2 0
XP_011523390 (OMIM: 610741) PREDICTED: trinucleoti (1729) 10002 923.3 0
XP_006722059 (OMIM: 610741) PREDICTED: trinucleoti (1971) 10002 923.3 0
NP_001136112 (OMIM: 610741) trinucleotide repeat-c (1726) 9965 920.0 0
XP_016880395 (OMIM: 610741) PREDICTED: trinucleoti (1968) 9965 920.0 0
XP_006722060 (OMIM: 610741) PREDICTED: trinucleoti (1921) 7227 671.5 2e-191
XP_016880397 (OMIM: 610741) PREDICTED: trinucleoti (1896) 5671 530.3 6.2e-149
XP_016878642 (OMIM: 610739) PREDICTED: trinucleoti (1709) 2525 244.8 4.9e-63
XP_005255314 (OMIM: 610739) PREDICTED: trinucleoti (1709) 2525 244.8 4.9e-63
XP_016878641 (OMIM: 610739) PREDICTED: trinucleoti (1829) 2525 244.8 5.2e-63
XP_016878635 (OMIM: 610739) PREDICTED: trinucleoti (1946) 2525 244.9 5.5e-63
NP_055309 (OMIM: 610739) trinucleotide repeat-cont (1962) 2525 244.9 5.5e-63
XP_016878632 (OMIM: 610739) PREDICTED: trinucleoti (1971) 2525 244.9 5.5e-63
XP_016878643 (OMIM: 610739) PREDICTED: trinucleoti (1698) 2108 207.0 1.2e-51
XP_016878633 (OMIM: 610739) PREDICTED: trinucleoti (1960) 2108 207.0 1.4e-51
XP_016878637 (OMIM: 610739) PREDICTED: trinucleoti (1912) 1731 172.8 2.6e-41
XP_016878634 (OMIM: 610739) PREDICTED: trinucleoti (1948) 1562 157.5 1.1e-36
NP_001317449 (OMIM: 610739) trinucleotide repeat-c (1913) 1352 138.4 5.9e-31
XP_016878636 (OMIM: 610739) PREDICTED: trinucleoti (1922) 1352 138.4 6e-31
XP_016878638 (OMIM: 610739) PREDICTED: trinucleoti (1911) 1303 134.0 1.3e-29
XP_016878639 (OMIM: 610739) PREDICTED: trinucleoti (1899) 1285 132.3 4e-29
NP_001155973 (OMIM: 610740) trinucleotide repeat-c (1833) 1210 125.5 4.3e-27
XP_016878640 (OMIM: 610739) PREDICTED: trinucleoti (1863) 1181 122.9 2.7e-26
NP_055903 (OMIM: 610740) trinucleotide repeat-cont (1723) 1046 110.6 1.2e-22
NP_001020014 (OMIM: 610740) trinucleotide repeat-c (1029) 872 94.7 4.5e-18
NP_001009931 (OMIM: 616293) hornerin [Homo sapiens (2850) 370 49.4 0.00056
>>NP_061869 (OMIM: 610741) trinucleotide repeat-containi (1690 aa)
initn: 11690 init1: 11690 opt: 11690 Z-score: 5747.4 bits: 1076.5 E(85289): 0
Smith-Waterman score: 11690; 100.0% identity (100.0% similar) in 1690 aa overlap (1-1690:1-1690)
10 20 30 40 50 60
pF1KA1 MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 GLAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 GLAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVAT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 TDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 TDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 AEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 AEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 GPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 GPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 TGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 TGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 RRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 RRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 ISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 ISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 PGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 PGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 KMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 KMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 HQAGTQLNRSPLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 HQAGTQLNRSPLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 GSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 GSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 WNNAASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 WNNAASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA1 LKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVDRPTFLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVDRPTFLDK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA1 DGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA1 NSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 NSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA1 SPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 SPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA1 QHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 QHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPN
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA1 TFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 TFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNP
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA1 SKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 SKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNG
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA1 SSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGKLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 SSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGKLSD
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA1 IKSTWSSGPTSHTQASLSHELWKVPRNSTAPTRPPPGLTNPKPSSTWGASPLGWTSSYSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 IKSTWSSGPTSHTQASLSHELWKVPRNSTAPTRPPPGLTNPKPSSTWGASPLGWTSSYSS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA1 GSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 GSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKE
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA1 EAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQSSSASSQPRLSAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 EAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQSSSASSQPRLSAAG
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA1 SSHGLVRSDAGHWNAPCLGGKGSSELLWGGVPQYSSSLWGPPSADDSRVIGSPTPLTTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 SSHGLVRSDAGHWNAPCLGGKGSSELLWGGVPQYSSSLWGPPSADDSRVIGSPTPLTTLL
1630 1640 1650 1660 1670 1680
1690
pF1KA1 PGDLLSGESL
::::::::::
NP_061 PGDLLSGESL
1690
>>XP_016880396 (OMIM: 610741) PREDICTED: trinucleotide r (1932 aa)
initn: 11690 init1: 11690 opt: 11690 Z-score: 5746.5 bits: 1076.5 E(85289): 0
Smith-Waterman score: 11690; 100.0% identity (100.0% similar) in 1690 aa overlap (1-1690:243-1932)
10 20 30
pF1KA1 MATGSAQGNFTGHTKKTNGNNGTNGALVQS
::::::::::::::::::::::::::::::
XP_016 PSITGTETESASECTTDTDSASNCGSENSSMATGSAQGNFTGHTKKTNGNNGTNGALVQS
220 230 240 250 260 270
40 50 60 70 80 90
pF1KA1 PSNQSALGAGGANSNGSAARVWGVATGSSSGLAHCSVSGGDGKMDTMIGDGRSQNCWGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSNQSALGAGGANSNGSAARVWGVATGSSSGLAHCSVSGGDGKMDTMIGDGRSQNCWGAS
280 290 300 310 320 330
100 110 120 130 140 150
pF1KA1 NSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGA
340 350 360 370 380 390
160 170 180 190 200 210
pF1KA1 WGNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WGNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGM
400 410 420 430 440 450
220 230 240 250 260 270
pF1KA1 AVGMGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVGMGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNG
460 470 480 490 500 510
280 290 300 310 320 330
pF1KA1 DTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGH
520 530 540 550 560 570
340 350 360 370 380 390
pF1KA1 PSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAAS
580 590 600 610 620 630
400 410 420 430 440 450
pF1KA1 SGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWG
640 650 660 670 680 690
460 470 480 490 500 510
pF1KA1 QTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWV
700 710 720 730 740 750
520 530 540 550 560 570
pF1KA1 NAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPT
760 770 780 790 800 810
580 590 600 610 620 630
pF1KA1 WGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGW
820 830 840 850 860 870
640 650 660 670 680 690
pF1KA1 NDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGT
880 890 900 910 920 930
700 710 720 730 740 750
pF1KA1 GWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNP
940 950 960 970 980 990
760 770 780 790 800 810
pF1KA1 VIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEMPNVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEMPNVH
1000 1010 1020 1030 1040 1050
820 830 840 850 860 870
pF1KA1 SKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASALCKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASALCKP
1060 1070 1080 1090 1100 1110
880 890 900 910 920 930
pF1KA1 ASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAPKKGLQKGMKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAPKKGLQKGMKT
1120 1130 1140 1150 1160 1170
940 950 960 970 980 990
pF1KA1 SGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVT
1180 1190 1200 1210 1220 1230
1000 1010 1020 1030 1040 1050
pF1KA1 DHNGMAAKPLGCRPPISKESSVDRPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHNGMAAKPLGCRPPISKESSVDRPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALPS
1240 1250 1260 1270 1280 1290
1060 1070 1080 1090 1100 1110
pF1KA1 QALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQARTMQQPPQPPVQPLNSSQPSLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQARTMQQPPQPPVQPLNSSQPSLRA
1300 1310 1320 1330 1340 1350
1120 1130 1140 1150 1160 1170
pF1KA1 QVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQLYQLQLAYQRLQIQQQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQLYQLQLAYQRLQIQQQM
1360 1370 1380 1390 1400 1410
1180 1190 1200 1210 1220 1230
pF1KA1 LQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSA
1420 1430 1440 1450 1460 1470
1240 1250 1260 1270 1280 1290
pF1KA1 GKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMDMTGGLSVKDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMDMTGGLSVKDP
1480 1490 1500 1510 1520 1530
1300 1310 1320 1330 1340 1350
pF1KA1 SQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLI
1540 1550 1560 1570 1580 1590
1360 1370 1380 1390 1400 1410
pF1KA1 QNSESPASPPVAVPHSWSRAKSDSDKISNGSSINWPPEFHPGVPWKGLQNIDPENDPDVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNSESPASPPVAVPHSWSRAKSDSDKISNGSSINWPPEFHPGVPWKGLQNIDPENDPDVT
1600 1610 1620 1630 1640 1650
1420 1430 1440 1450 1460 1470
pF1KA1 PGSVPTGPTINTTIQDVNRYLLKSGGKLSDIKSTWSSGPTSHTQASLSHELWKVPRNSTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGSVPTGPTINTTIQDVNRYLLKSGGKLSDIKSTWSSGPTSHTQASLSHELWKVPRNSTA
1660 1670 1680 1690 1700 1710
1480 1490 1500 1510 1520 1530
pF1KA1 PTRPPPGLTNPKPSSTWGASPLGWTSSYSSGSAWSTDTSGRTSSWLVLRNLTPQIDGSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTRPPPGLTNPKPSSTWGASPLGWTSSYSSGSAWSTDTSGRTSSWLVLRNLTPQIDGSTL
1720 1730 1740 1750 1760 1770
1540 1550 1560 1570 1580 1590
pF1KA1 RTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVN
1780 1790 1800 1810 1820 1830
1600 1610 1620 1630 1640 1650
pF1KA1 RFLAQGQALPPTSSWQSSSASSQPRLSAAGSSHGLVRSDAGHWNAPCLGGKGSSELLWGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFLAQGQALPPTSSWQSSSASSQPRLSAAGSSHGLVRSDAGHWNAPCLGGKGSSELLWGG
1840 1850 1860 1870 1880 1890
1660 1670 1680 1690
pF1KA1 VPQYSSSLWGPPSADDSRVIGSPTPLTTLLPGDLLSGESL
::::::::::::::::::::::::::::::::::::::::
XP_016 VPQYSSSLWGPPSADDSRVIGSPTPLTTLLPGDLLSGESL
1900 1910 1920 1930
>>XP_006722063 (OMIM: 610741) PREDICTED: trinucleotide r (1929 aa)
initn: 6128 init1: 6128 opt: 11653 Z-score: 5728.4 bits: 1073.2 E(85289): 0
Smith-Waterman score: 11653; 99.8% identity (99.8% similar) in 1690 aa overlap (1-1690:243-1929)
10 20 30
pF1KA1 MATGSAQGNFTGHTKKTNGNNGTNGALVQS
::::::::::::::::::::::::::::::
XP_006 PSITGTETESASECTTDTDSASNCGSENSSMATGSAQGNFTGHTKKTNGNNGTNGALVQS
220 230 240 250 260 270
40 50 60 70 80 90
pF1KA1 PSNQSALGAGGANSNGSAARVWGVATGSSSGLAHCSVSGGDGKMDTMIGDGRSQNCWGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSNQSALGAGGANSNGSAARVWGVATGSSSGLAHCSVSGGDGKMDTMIGDGRSQNCWGAS
280 290 300 310 320 330
100 110 120 130 140 150
pF1KA1 NSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGA
340 350 360 370 380 390
160 170 180 190 200 210
pF1KA1 WGNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WGNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGM
400 410 420 430 440 450
220 230 240 250 260 270
pF1KA1 AVGMGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVGMGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNG
460 470 480 490 500 510
280 290 300 310 320 330
pF1KA1 DTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGH
520 530 540 550 560 570
340 350 360 370 380 390
pF1KA1 PSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAAS
580 590 600 610 620 630
400 410 420 430 440 450
pF1KA1 SGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWG
640 650 660 670 680 690
460 470 480 490 500 510
pF1KA1 QTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWV
700 710 720 730 740 750
520 530 540 550 560 570
pF1KA1 NAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPT
760 770 780 790 800 810
580 590 600 610 620 630
pF1KA1 WGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGW
820 830 840 850 860 870
640 650 660 670 680 690
pF1KA1 NDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGT
880 890 900 910 920 930
700 710 720 730 740 750
pF1KA1 GWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNP
940 950 960 970 980 990
760 770 780 790 800 810
pF1KA1 VIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEMPNVH
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_006 VIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGP---VSSGWGEMPNVH
1000 1010 1020 1030 1040
820 830 840 850 860 870
pF1KA1 SKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASALCKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASALCKP
1050 1060 1070 1080 1090 1100
880 890 900 910 920 930
pF1KA1 ASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAPKKGLQKGMKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAPKKGLQKGMKT
1110 1120 1130 1140 1150 1160
940 950 960 970 980 990
pF1KA1 SGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVT
1170 1180 1190 1200 1210 1220
1000 1010 1020 1030 1040 1050
pF1KA1 DHNGMAAKPLGCRPPISKESSVDRPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DHNGMAAKPLGCRPPISKESSVDRPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALPS
1230 1240 1250 1260 1270 1280
1060 1070 1080 1090 1100 1110
pF1KA1 QALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQARTMQQPPQPPVQPLNSSQPSLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQARTMQQPPQPPVQPLNSSQPSLRA
1290 1300 1310 1320 1330 1340
1120 1130 1140 1150 1160 1170
pF1KA1 QVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQLYQLQLAYQRLQIQQQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQLYQLQLAYQRLQIQQQM
1350 1360 1370 1380 1390 1400
1180 1190 1200 1210 1220 1230
pF1KA1 LQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSA
1410 1420 1430 1440 1450 1460
1240 1250 1260 1270 1280 1290
pF1KA1 GKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMDMTGGLSVKDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMDMTGGLSVKDP
1470 1480 1490 1500 1510 1520
1300 1310 1320 1330 1340 1350
pF1KA1 SQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLI
1530 1540 1550 1560 1570 1580
1360 1370 1380 1390 1400 1410
pF1KA1 QNSESPASPPVAVPHSWSRAKSDSDKISNGSSINWPPEFHPGVPWKGLQNIDPENDPDVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QNSESPASPPVAVPHSWSRAKSDSDKISNGSSINWPPEFHPGVPWKGLQNIDPENDPDVT
1590 1600 1610 1620 1630 1640
1420 1430 1440 1450 1460 1470
pF1KA1 PGSVPTGPTINTTIQDVNRYLLKSGGKLSDIKSTWSSGPTSHTQASLSHELWKVPRNSTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PGSVPTGPTINTTIQDVNRYLLKSGGKLSDIKSTWSSGPTSHTQASLSHELWKVPRNSTA
1650 1660 1670 1680 1690 1700
1480 1490 1500 1510 1520 1530
pF1KA1 PTRPPPGLTNPKPSSTWGASPLGWTSSYSSGSAWSTDTSGRTSSWLVLRNLTPQIDGSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PTRPPPGLTNPKPSSTWGASPLGWTSSYSSGSAWSTDTSGRTSSWLVLRNLTPQIDGSTL
1710 1720 1730 1740 1750 1760
1540 1550 1560 1570 1580 1590
pF1KA1 RTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVN
1770 1780 1790 1800 1810 1820
1600 1610 1620 1630 1640 1650
pF1KA1 RFLAQGQALPPTSSWQSSSASSQPRLSAAGSSHGLVRSDAGHWNAPCLGGKGSSELLWGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RFLAQGQALPPTSSWQSSSASSQPRLSAAGSSHGLVRSDAGHWNAPCLGGKGSSELLWGG
1830 1840 1850 1860 1870 1880
1660 1670 1680 1690
pF1KA1 VPQYSSSLWGPPSADDSRVIGSPTPLTTLLPGDLLSGESL
::::::::::::::::::::::::::::::::::::::::
XP_006 VPQYSSSLWGPPSADDSRVIGSPTPLTTLLPGDLLSGESL
1890 1900 1910 1920
>>XP_011523390 (OMIM: 610741) PREDICTED: trinucleotide r (1729 aa)
initn: 9970 init1: 9970 opt: 10002 Z-score: 4919.4 bits: 923.3 E(85289): 0
Smith-Waterman score: 11563; 97.7% identity (97.7% similar) in 1722 aa overlap (1-1683:1-1722)
10 20 30 40 50 60
pF1KA1 MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 GLAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVAT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 TDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 AEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 GPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 TGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 RRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 ISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 PGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 KMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 HQAGTQLNRSPLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQAGTQLNRSPLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 GSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 WNNAASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WNNAASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA1 LKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVDRPTFLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVDRPTFLDK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA1 DGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA1 NSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA1 SPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA1 QHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPN
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA1 TFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNP
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA1 SKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNG
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430
pF1KA1 SSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGG----
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGSSPP
1390 1400 1410 1420 1430 1440
1440 1450 1460
pF1KA1 -----------------------------------KLSDIKSTWSSGPTSHTQASLSHEL
:::::::::::::::::::::::::
XP_011 SSQNATLPSSSAWPLSASGYSSSFSSIASAPSVAGKLSDIKSTWSSGPTSHTQASLSHEL
1450 1460 1470 1480 1490 1500
1470 1480 1490 1500 1510 1520
pF1KA1 WKVPRNSTAPTRPPPGLTNPKPSSTWGASPLGWTSSYSSGSAWSTDTSGRTSSWLVLRNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WKVPRNSTAPTRPPPGLTNPKPSSTWGASPLGWTSSYSSGSAWSTDTSGRTSSWLVLRNL
1510 1520 1530 1540 1550 1560
1530 1540 1550 1560 1570 1580
pF1KA1 TPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILA
1570 1580 1590 1600 1610 1620
1590 1600 1610 1620 1630 1640
pF1KA1 EFAGEEEVNRFLAQGQALPPTSSWQSSSASSQPRLSAAGSSHGLVRSDAGHWNAPCLGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFAGEEEVNRFLAQGQALPPTSSWQSSSASSQPRLSAAGSSHGLVRSDAGHWNAPCLGGK
1630 1640 1650 1660 1670 1680
1650 1660 1670 1680 1690
pF1KA1 GSSELLWGGVPQYSSSLWGPPSADDSRVIGSPTPLTTLLPGDLLSGESL
::::::::::::::::::::::::::::::::::::::::::
XP_011 GSSELLWGGVPQYSSSLWGPPSADDSRVIGSPTPLTTLLPGDLLSGESL
1690 1700 1710 1720
>>XP_006722059 (OMIM: 610741) PREDICTED: trinucleotide r (1971 aa)
initn: 9970 init1: 9970 opt: 10002 Z-score: 4918.5 bits: 923.3 E(85289): 0
Smith-Waterman score: 11563; 97.7% identity (97.7% similar) in 1722 aa overlap (1-1683:243-1964)
10 20 30
pF1KA1 MATGSAQGNFTGHTKKTNGNNGTNGALVQS
::::::::::::::::::::::::::::::
XP_006 PSITGTETESASECTTDTDSASNCGSENSSMATGSAQGNFTGHTKKTNGNNGTNGALVQS
220 230 240 250 260 270
40 50 60 70 80 90
pF1KA1 PSNQSALGAGGANSNGSAARVWGVATGSSSGLAHCSVSGGDGKMDTMIGDGRSQNCWGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSNQSALGAGGANSNGSAARVWGVATGSSSGLAHCSVSGGDGKMDTMIGDGRSQNCWGAS
280 290 300 310 320 330
100 110 120 130 140 150
pF1KA1 NSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGA
340 350 360 370 380 390
160 170 180 190 200 210
pF1KA1 WGNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WGNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGM
400 410 420 430 440 450
220 230 240 250 260 270
pF1KA1 AVGMGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVGMGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNG
460 470 480 490 500 510
280 290 300 310 320 330
pF1KA1 DTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGH
520 530 540 550 560 570
340 350 360 370 380 390
pF1KA1 PSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAAS
580 590 600 610 620 630
400 410 420 430 440 450
pF1KA1 SGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWG
640 650 660 670 680 690
460 470 480 490 500 510
pF1KA1 QTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWV
700 710 720 730 740 750
520 530 540 550 560 570
pF1KA1 NAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPT
760 770 780 790 800 810
580 590 600 610 620 630
pF1KA1 WGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGW
820 830 840 850 860 870
640 650 660 670 680 690
pF1KA1 NDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGT
880 890 900 910 920 930
700 710 720 730 740 750
pF1KA1 GWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNP
940 950 960 970 980 990
760 770 780 790 800 810
pF1KA1 VIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEMPNVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEMPNVH
1000 1010 1020 1030 1040 1050
820 830 840 850 860 870
pF1KA1 SKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASALCKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASALCKP
1060 1070 1080 1090 1100 1110
880 890 900 910 920 930
pF1KA1 ASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAPKKGLQKGMKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAPKKGLQKGMKT
1120 1130 1140 1150 1160 1170
940 950 960 970 980 990
pF1KA1 SGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVT
1180 1190 1200 1210 1220 1230
1000 1010 1020 1030 1040 1050
pF1KA1 DHNGMAAKPLGCRPPISKESSVDRPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DHNGMAAKPLGCRPPISKESSVDRPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALPS
1240 1250 1260 1270 1280 1290
1060 1070 1080 1090 1100 1110
pF1KA1 QALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQARTMQQPPQPPVQPLNSSQPSLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQARTMQQPPQPPVQPLNSSQPSLRA
1300 1310 1320 1330 1340 1350
1120 1130 1140 1150 1160 1170
pF1KA1 QVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQLYQLQLAYQRLQIQQQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQLYQLQLAYQRLQIQQQM
1360 1370 1380 1390 1400 1410
1180 1190 1200 1210 1220 1230
pF1KA1 LQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSA
1420 1430 1440 1450 1460 1470
1240 1250 1260 1270 1280 1290
pF1KA1 GKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMDMTGGLSVKDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMDMTGGLSVKDP
1480 1490 1500 1510 1520 1530
1300 1310 1320 1330 1340 1350
pF1KA1 SQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLI
1540 1550 1560 1570 1580 1590
1360 1370 1380 1390 1400 1410
pF1KA1 QNSESPASPPVAVPHSWSRAKSDSDKISNGSSINWPPEFHPGVPWKGLQNIDPENDPDVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QNSESPASPPVAVPHSWSRAKSDSDKISNGSSINWPPEFHPGVPWKGLQNIDPENDPDVT
1600 1610 1620 1630 1640 1650
1420 1430
pF1KA1 PGSVPTGPTINTTIQDVNRYLLKSGG----------------------------------
::::::::::::::::::::::::::
XP_006 PGSVPTGPTINTTIQDVNRYLLKSGGSSPPSSQNATLPSSSAWPLSASGYSSSFSSIASA
1660 1670 1680 1690 1700 1710
1440 1450 1460 1470 1480 1490
pF1KA1 -----KLSDIKSTWSSGPTSHTQASLSHELWKVPRNSTAPTRPPPGLTNPKPSSTWGASP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSVAGKLSDIKSTWSSGPTSHTQASLSHELWKVPRNSTAPTRPPPGLTNPKPSSTWGASP
1720 1730 1740 1750 1760 1770
1500 1510 1520 1530 1540 1550
pF1KA1 LGWTSSYSSGSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGWTSSYSSGSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGN
1780 1790 1800 1810 1820 1830
1560 1570 1580 1590 1600 1610
pF1KA1 AVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQSSSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQSSSAS
1840 1850 1860 1870 1880 1890
1620 1630 1640 1650 1660 1670
pF1KA1 SQPRLSAAGSSHGLVRSDAGHWNAPCLGGKGSSELLWGGVPQYSSSLWGPPSADDSRVIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQPRLSAAGSSHGLVRSDAGHWNAPCLGGKGSSELLWGGVPQYSSSLWGPPSADDSRVIG
1900 1910 1920 1930 1940 1950
1680 1690
pF1KA1 SPTPLTTLLPGDLLSGESL
::::::::::::
XP_006 SPTPLTTLLPGDLLSGESL
1960 1970
>>NP_001136112 (OMIM: 610741) trinucleotide repeat-conta (1726 aa)
initn: 7346 init1: 5552 opt: 9965 Z-score: 4901.3 bits: 920.0 E(85289): 0
Smith-Waterman score: 11541; 97.6% identity (97.6% similar) in 1725 aa overlap (1-1686:1-1722)
10 20 30 40 50 60
pF1KA1 MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 GLAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVAT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 TDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 AEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 GPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 TGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 RRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 ISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 PGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 KMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 HQAGTQLNRSPLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSS
::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
NP_001 HQAGTQLNRSPLLGP---VSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSS
790 800 810 820 830
850 860 870 880 890 900
pF1KA1 GSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDV
840 850 860 870 880 890
910 920 930 940 950 960
pF1KA1 WNNAASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WNNAASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEA
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KA1 LKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVDRPTFLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVDRPTFLDK
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KA1 DGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFG
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KA1 NSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLT
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KA1 SPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQ
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KA1 QHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPN
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KA1 TFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNP
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KA1 SKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNG
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430
pF1KA1 SSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGG----
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGSSPP
1380 1390 1400 1410 1420 1430
1440 1450 1460
pF1KA1 -----------------------------------KLSDIKSTWSSGPTSHTQASLSHEL
:::::::::::::::::::::::::
NP_001 SSQNATLPSSSAWPLSASGYSSSFSSIASAPSVAGKLSDIKSTWSSGPTSHTQASLSHEL
1440 1450 1460 1470 1480 1490
1470 1480 1490 1500 1510 1520
pF1KA1 WKVPRNSTAPTRPPPGLTNPKPSSTWGASPLGWTSSYSSGSAWSTDTSGRTSSWLVLRNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WKVPRNSTAPTRPPPGLTNPKPSSTWGASPLGWTSSYSSGSAWSTDTSGRTSSWLVLRNL
1500 1510 1520 1530 1540 1550
1530 1540 1550 1560 1570 1580
pF1KA1 TPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILA
1560 1570 1580 1590 1600 1610
1590 1600 1610 1620 1630 1640
pF1KA1 EFAGEEEVNRFLAQGQALPPTSSWQSSSASSQPRLSAAGSSHGLVRSDAGHWNAPCLGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFAGEEEVNRFLAQGQALPPTSSWQSSSASSQPRLSAAGSSHGLVRSDAGHWNAPCLGGK
1620 1630 1640 1650 1660 1670
1650 1660 1670 1680 1690
pF1KA1 GSSELLWGGVPQYSSSLWGPPSADDSRVIGSPTPLTTLLPGDLLSGESL
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSELLWGGVPQYSSSLWGPPSADDSRVIGSPTPLTTLLPGDLLSGESL
1680 1690 1700 1710 1720
>>XP_016880395 (OMIM: 610741) PREDICTED: trinucleotide r (1968 aa)
initn: 7346 init1: 5552 opt: 9965 Z-score: 4900.4 bits: 920.0 E(85289): 0
Smith-Waterman score: 11541; 97.6% identity (97.6% similar) in 1725 aa overlap (1-1686:243-1964)
10 20 30
pF1KA1 MATGSAQGNFTGHTKKTNGNNGTNGALVQS
::::::::::::::::::::::::::::::
XP_016 PSITGTETESASECTTDTDSASNCGSENSSMATGSAQGNFTGHTKKTNGNNGTNGALVQS
220 230 240 250 260 270
40 50 60 70 80 90
pF1KA1 PSNQSALGAGGANSNGSAARVWGVATGSSSGLAHCSVSGGDGKMDTMIGDGRSQNCWGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSNQSALGAGGANSNGSAARVWGVATGSSSGLAHCSVSGGDGKMDTMIGDGRSQNCWGAS
280 290 300 310 320 330
100 110 120 130 140 150
pF1KA1 NSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGA
340 350 360 370 380 390
160 170 180 190 200 210
pF1KA1 WGNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WGNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGM
400 410 420 430 440 450
220 230 240 250 260 270
pF1KA1 AVGMGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVGMGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNG
460 470 480 490 500 510
280 290 300 310 320 330
pF1KA1 DTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGH
520 530 540 550 560 570
340 350 360 370 380 390
pF1KA1 PSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAAS
580 590 600 610 620 630
400 410 420 430 440 450
pF1KA1 SGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWG
640 650 660 670 680 690
460 470 480 490 500 510
pF1KA1 QTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWV
700 710 720 730 740 750
520 530 540 550 560 570
pF1KA1 NAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPT
760 770 780 790 800 810
580 590 600 610 620 630
pF1KA1 WGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGW
820 830 840 850 860 870
640 650 660 670 680 690
pF1KA1 NDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGT
880 890 900 910 920 930
700 710 720 730 740 750
pF1KA1 GWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNP
940 950 960 970 980 990
760 770 780 790 800 810
pF1KA1 VIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEMPNVH
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_016 VIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGP---VSSGWGEMPNVH
1000 1010 1020 1030 1040
820 830 840 850 860 870
pF1KA1 SKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASALCKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASALCKP
1050 1060 1070 1080 1090 1100
880 890 900 910 920 930
pF1KA1 ASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAPKKGLQKGMKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAPKKGLQKGMKT
1110 1120 1130 1140 1150 1160
940 950 960 970 980 990
pF1KA1 SGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVT
1170 1180 1190 1200 1210 1220
1000 1010 1020 1030 1040 1050
pF1KA1 DHNGMAAKPLGCRPPISKESSVDRPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHNGMAAKPLGCRPPISKESSVDRPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALPS
1230 1240 1250 1260 1270 1280
1060 1070 1080 1090 1100 1110
pF1KA1 QALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQARTMQQPPQPPVQPLNSSQPSLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQARTMQQPPQPPVQPLNSSQPSLRA
1290 1300 1310 1320 1330 1340
1120 1130 1140 1150 1160 1170
pF1KA1 QVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQLYQLQLAYQRLQIQQQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQLYQLQLAYQRLQIQQQM
1350 1360 1370 1380 1390 1400
1180 1190 1200 1210 1220 1230
pF1KA1 LQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSA
1410 1420 1430 1440 1450 1460
1240 1250 1260 1270 1280 1290
pF1KA1 GKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMDMTGGLSVKDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMDMTGGLSVKDP
1470 1480 1490 1500 1510 1520
1300 1310 1320 1330 1340 1350
pF1KA1 SQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLI
1530 1540 1550 1560 1570 1580
1360 1370 1380 1390 1400 1410
pF1KA1 QNSESPASPPVAVPHSWSRAKSDSDKISNGSSINWPPEFHPGVPWKGLQNIDPENDPDVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNSESPASPPVAVPHSWSRAKSDSDKISNGSSINWPPEFHPGVPWKGLQNIDPENDPDVT
1590 1600 1610 1620 1630 1640
1420 1430
pF1KA1 PGSVPTGPTINTTIQDVNRYLLKSGG----------------------------------
::::::::::::::::::::::::::
XP_016 PGSVPTGPTINTTIQDVNRYLLKSGGSSPPSSQNATLPSSSAWPLSASGYSSSFSSIASA
1650 1660 1670 1680 1690 1700
1440 1450 1460 1470 1480 1490
pF1KA1 -----KLSDIKSTWSSGPTSHTQASLSHELWKVPRNSTAPTRPPPGLTNPKPSSTWGASP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSVAGKLSDIKSTWSSGPTSHTQASLSHELWKVPRNSTAPTRPPPGLTNPKPSSTWGASP
1710 1720 1730 1740 1750 1760
1500 1510 1520 1530 1540 1550
pF1KA1 LGWTSSYSSGSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGWTSSYSSGSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGN
1770 1780 1790 1800 1810 1820
1560 1570 1580 1590 1600 1610
pF1KA1 AVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQSSSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQSSSAS
1830 1840 1850 1860 1870 1880
1620 1630 1640 1650 1660 1670
pF1KA1 SQPRLSAAGSSHGLVRSDAGHWNAPCLGGKGSSELLWGGVPQYSSSLWGPPSADDSRVIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQPRLSAAGSSHGLVRSDAGHWNAPCLGGKGSSELLWGGVPQYSSSLWGPPSADDSRVIG
1890 1900 1910 1920 1930 1940
1680 1690
pF1KA1 SPTPLTTLLPGDLLSGESL
:::::::::::::::
XP_016 SPTPLTTLLPGDLLSGESL
1950 1960
>>XP_006722060 (OMIM: 610741) PREDICTED: trinucleotide r (1921 aa)
initn: 8910 init1: 7116 opt: 7227 Z-score: 3557.8 bits: 671.5 E(85289): 2e-191
Smith-Waterman score: 11161; 94.9% identity (94.9% similar) in 1729 aa overlap (1-1690:243-1921)
10 20 30
pF1KA1 MATGSAQGNFTGHTKKTNGNNGTNGALVQS
::::::::::::::::::::::::::::::
XP_006 PSITGTETESASECTTDTDSASNCGSENSSMATGSAQGNFTGHTKKTNGNNGTNGALVQS
220 230 240 250 260 270
40 50 60 70 80 90
pF1KA1 PSNQSALGAGGANSNGSAARVWGVATGSSSGLAHCSVSGGDGKMDTMIGDGRSQNCWGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSNQSALGAGGANSNGSAARVWGVATGSSSGLAHCSVSGGDGKMDTMIGDGRSQNCWGAS
280 290 300 310 320 330
100 110 120 130 140 150
pF1KA1 NSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGA
340 350 360 370 380 390
160 170 180 190 200 210
pF1KA1 WGNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WGNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGM
400 410 420 430 440 450
220 230 240 250 260 270
pF1KA1 AVGMGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVGMGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNG
460 470 480 490 500 510
280 290 300 310 320 330
pF1KA1 DTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGH
520 530 540 550 560 570
340 350 360 370 380 390
pF1KA1 PSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAAS
580 590 600 610 620 630
400 410 420 430 440 450
pF1KA1 SGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWG
640 650 660 670 680 690
460 470 480 490 500 510
pF1KA1 QTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWV
700 710 720 730 740 750
520 530 540 550 560 570
pF1KA1 NAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPT
760 770 780 790 800 810
580 590 600 610 620 630
pF1KA1 WGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGW
820 830 840 850 860 870
640 650 660 670 680 690
pF1KA1 NDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGT
880 890 900 910 920 930
700 710 720 730 740 750
pF1KA1 GWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNP
940 950 960 970 980 990
760 770 780 790 800 810
pF1KA1 VIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEMPNVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEMPNVH
1000 1010 1020 1030 1040 1050
820 830 840 850 860 870
pF1KA1 SKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASALCKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASALCKP
1060 1070 1080 1090 1100 1110
880 890 900 910 920 930
pF1KA1 ASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAPKKGLQKGMKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAPKKGLQKGMKT
1120 1130 1140 1150 1160 1170
940 950 960 970 980 990
pF1KA1 SGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVT
1180 1190 1200 1210 1220 1230
1000 1010 1020 1030 1040 1050
pF1KA1 DHNGMAAKPLGCRPPISKESSVDRPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALPS
::::::::::::::::::::::::::::::
XP_006 DHNGMAAKPLGCRPPISKESSVDRPTFLDK------------------------------
1240 1250 1260
1060 1070 1080 1090 1100 1110
pF1KA1 QALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQARTMQQPPQPPVQPLNSSQPSLRA
::::::::::::::::::::::::::::::::::::::::
XP_006 --------------------IPSGNLGMFGNSGAAQARTMQQPPQPPVQPLNSSQPSLRA
1270 1280 1290 1300
1120 1130 1140 1150 1160 1170
pF1KA1 QVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQLYQLQLAYQRLQIQQQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQLYQLQLAYQRLQIQQQM
1310 1320 1330 1340 1350 1360
1180 1190 1200 1210 1220 1230
pF1KA1 LQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSA
1370 1380 1390 1400 1410 1420
1240 1250 1260 1270 1280 1290
pF1KA1 GKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMDMTGGLSVKDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMDMTGGLSVKDP
1430 1440 1450 1460 1470 1480
1300 1310 1320 1330 1340 1350
pF1KA1 SQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLI
1490 1500 1510 1520 1530 1540
1360 1370 1380 1390 1400 1410
pF1KA1 QNSESPASPPVAVPHSWSRAKSDSDKISNGSSINWPPEFHPGVPWKGLQNIDPENDPDVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QNSESPASPPVAVPHSWSRAKSDSDKISNGSSINWPPEFHPGVPWKGLQNIDPENDPDVT
1550 1560 1570 1580 1590 1600
1420 1430
pF1KA1 PGSVPTGPTINTTIQDVNRYLLKSGG----------------------------------
::::::::::::::::::::::::::
XP_006 PGSVPTGPTINTTIQDVNRYLLKSGGSSPPSSQNATLPSSSAWPLSASGYSSSFSSIASA
1610 1620 1630 1640 1650 1660
1440 1450 1460 1470 1480 1490
pF1KA1 -----KLSDIKSTWSSGPTSHTQASLSHELWKVPRNSTAPTRPPPGLTNPKPSSTWGASP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSVAGKLSDIKSTWSSGPTSHTQASLSHELWKVPRNSTAPTRPPPGLTNPKPSSTWGASP
1670 1680 1690 1700 1710 1720
1500 1510 1520 1530 1540 1550
pF1KA1 LGWTSSYSSGSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGWTSSYSSGSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGN
1730 1740 1750 1760 1770 1780
1560 1570 1580 1590 1600 1610
pF1KA1 AVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQSSSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQSSSAS
1790 1800 1810 1820 1830 1840
1620 1630 1640 1650 1660 1670
pF1KA1 SQPRLSAAGSSHGLVRSDAGHWNAPCLGGKGSSELLWGGVPQYSSSLWGPPSADDSRVIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQPRLSAAGSSHGLVRSDAGHWNAPCLGGKGSSELLWGGVPQYSSSLWGPPSADDSRVIG
1850 1860 1870 1880 1890 1900
1680 1690
pF1KA1 SPTPLTTLLPGDLLSGESL
:::::::::::::::::::
XP_006 SPTPLTTLLPGDLLSGESL
1910 1920
>>XP_016880397 (OMIM: 610741) PREDICTED: trinucleotide r (1896 aa)
initn: 7351 init1: 5557 opt: 5671 Z-score: 2794.8 bits: 530.3 E(85289): 6.2e-149
Smith-Waterman score: 10897; 93.4% identity (93.4% similar) in 1729 aa overlap (1-1690:243-1896)
10 20 30
pF1KA1 MATGSAQGNFTGHTKKTNGNNGTNGALVQS
::::::::::::::::::::::::::::::
XP_016 PSITGTETESASECTTDTDSASNCGSENSSMATGSAQGNFTGHTKKTNGNNGTNGALVQS
220 230 240 250 260 270
40 50 60 70 80 90
pF1KA1 PSNQSALGAGGANSNGSAARVWGVATGSSSGLAHCSVSGGDGKMDTMIGDGRSQNCWGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSNQSALGAGGANSNGSAARVWGVATGSSSGLAHCSVSGGDGKMDTMIGDGRSQNCWGAS
280 290 300 310 320 330
100 110 120 130 140 150
pF1KA1 NSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGA
340 350 360 370 380 390
160 170 180 190 200 210
pF1KA1 WGNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WGNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGM
400 410 420 430 440 450
220 230 240 250 260 270
pF1KA1 AVGMGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVGMGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNG
460 470 480 490 500 510
280 290 300 310 320 330
pF1KA1 DTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGH
520 530 540 550 560 570
340 350 360 370 380 390
pF1KA1 PSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAAS
580 590 600 610 620 630
400 410 420 430 440 450
pF1KA1 SGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWG
640 650 660 670 680 690
460 470 480 490 500 510
pF1KA1 QTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWV
700 710 720 730 740 750
520 530 540 550 560 570
pF1KA1 NAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPT
760 770 780 790 800 810
580 590 600 610 620 630
pF1KA1 WGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGW
820 830 840 850 860 870
640 650 660 670 680 690
pF1KA1 NDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGT
880 890 900 910 920 930
700 710 720 730 740 750
pF1KA1 GWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNP
940 950 960 970 980 990
760 770 780 790 800 810
pF1KA1 VIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEMPNVH
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGP---------------
1000 1010 1020 1030
820 830 840 850 860 870
pF1KA1 SKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASALCKP
XP_016 ------------------------------------------------------------
880 890 900 910 920 930
pF1KA1 ASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAPKKGLQKGMKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAPKKGLQKGMKT
1040 1050 1060 1070 1080 1090
940 950 960 970 980 990
pF1KA1 SGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVT
1100 1110 1120 1130 1140 1150
1000 1010 1020 1030 1040 1050
pF1KA1 DHNGMAAKPLGCRPPISKESSVDRPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHNGMAAKPLGCRPPISKESSVDRPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALPS
1160 1170 1180 1190 1200 1210
1060 1070 1080 1090 1100 1110
pF1KA1 QALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQARTMQQPPQPPVQPLNSSQPSLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQARTMQQPPQPPVQPLNSSQPSLRA
1220 1230 1240 1250 1260 1270
1120 1130 1140 1150 1160 1170
pF1KA1 QVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQLYQLQLAYQRLQIQQQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQLYQLQLAYQRLQIQQQM
1280 1290 1300 1310 1320 1330
1180 1190 1200 1210 1220 1230
pF1KA1 LQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSA
1340 1350 1360 1370 1380 1390
1240 1250 1260 1270 1280 1290
pF1KA1 GKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMDMTGGLSVKDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMDMTGGLSVKDP
1400 1410 1420 1430 1440 1450
1300 1310 1320 1330 1340 1350
pF1KA1 SQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLI
1460 1470 1480 1490 1500 1510
1360 1370 1380 1390 1400 1410
pF1KA1 QNSESPASPPVAVPHSWSRAKSDSDKISNGSSINWPPEFHPGVPWKGLQNIDPENDPDVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNSESPASPPVAVPHSWSRAKSDSDKISNGSSINWPPEFHPGVPWKGLQNIDPENDPDVT
1520 1530 1540 1550 1560 1570
1420 1430
pF1KA1 PGSVPTGPTINTTIQDVNRYLLKSGG----------------------------------
::::::::::::::::::::::::::
XP_016 PGSVPTGPTINTTIQDVNRYLLKSGGSSPPSSQNATLPSSSAWPLSASGYSSSFSSIASA
1580 1590 1600 1610 1620 1630
1440 1450 1460 1470 1480 1490
pF1KA1 -----KLSDIKSTWSSGPTSHTQASLSHELWKVPRNSTAPTRPPPGLTNPKPSSTWGASP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSVAGKLSDIKSTWSSGPTSHTQASLSHELWKVPRNSTAPTRPPPGLTNPKPSSTWGASP
1640 1650 1660 1670 1680 1690
1500 1510 1520 1530 1540 1550
pF1KA1 LGWTSSYSSGSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGWTSSYSSGSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGN
1700 1710 1720 1730 1740 1750
1560 1570 1580 1590 1600 1610
pF1KA1 AVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQSSSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQSSSAS
1760 1770 1780 1790 1800 1810
1620 1630 1640 1650 1660 1670
pF1KA1 SQPRLSAAGSSHGLVRSDAGHWNAPCLGGKGSSELLWGGVPQYSSSLWGPPSADDSRVIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQPRLSAAGSSHGLVRSDAGHWNAPCLGGKGSSELLWGGVPQYSSSLWGPPSADDSRVIG
1820 1830 1840 1850 1860 1870
1680 1690
pF1KA1 SPTPLTTLLPGDLLSGESL
:::::::::::::::::::
XP_016 SPTPLTTLLPGDLLSGESL
1880 1890
>>XP_016878642 (OMIM: 610739) PREDICTED: trinucleotide r (1709 aa)
initn: 2313 init1: 631 opt: 2525 Z-score: 1252.7 bits: 244.8 E(85289): 4.9e-63
Smith-Waterman score: 4184; 43.7% identity (67.6% similar) in 1820 aa overlap (1-1687:18-1704)
10 20 30 40
pF1KA1 MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGAN
::.:.. :. : ....: .. : .: : ::. .: ..
XP_016 MDADSASSSESERNITIMASGNTGGEKDG-LRNSTGLGSQNKFVVGSSSNN----VGHGS
10 20 30 40 50
50 60 70 80 90 100
pF1KA1 SNGSAARVWGVATGSSSGLAHCSVSGGDGKMDTMIGDGRSQNCWG--ASNSNAGINLN-L
:.: :: . :. . . ::.. ..: .. ...: .: :: .:.::.:.: . :
XP_016 STGP----WGFSHGAIISTCQVSVDAPESKSES--SNNR-MNAWGTVSSSSNGGLNPSTL
60 70 80 90 100
110 120 130 140 150
pF1KA1 NPNANPAAWPVLGHEGTVATGNPSSICSPV----SAIGQNMGNQ--NGNPTG--TLGAWG
: .: .::::: ..: . : .: : . :.::: .:: :.. .: : :.::
XP_016 NSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWG
110 120 130 140 150 160
160 170 180 190 200
pF1KA1 NLLPQESTEPQTSTSQNVSFSAQPQNLNTD--GPNNT-NPMNSS-PNPINAMQTNGLP--
.: ::. : ..: .:.::::.::::..:. ::::: : :.:: :: ...:.: ::
XP_016 SL--QETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNS-GSVQNNELPSS
170 180 190 200 210 220
210 220 230 240 250 260
pF1KA1 NWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGSAE--GISNSVWGLSPGNPATGNSNSG
: : : .... :..:. : ::.:.:..:.: .. : ...:: . :. .:.. ::
XP_016 NTG-AWRVSTMNHPQMQAPSGMNGTSLSHLSNGESKSGGSYGTTWG-AYGSNYSGDKCSG
230 240 250 260 270 280
270 280 290 300 310 320
pF1KA1 FS-QGNGDTVNSALSAKQ-NGS-SSAVQ-KEGSGGNAWDSGPPAGPGILAWGRGSGNNGV
. :.::::::..: :: .. : . ..::..:.:: :. .:: :.: :.
XP_016 PNGQANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGA-ANSQSTSWGSGNGANS-
290 300 310 320 330 340
330 340 350 360 370
pF1KA1 GNIHSGAWGHPSRSTSNGVNG-EWGK-PPNQHSNSDINGKGST---GWESPSVTSQNPTV
:. . : :: :...:.... . ::.: : :::::.. ::.:.: ::.: .:. ..
XP_016 GGSRRG-WGTPAQNTGTNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSAT
350 360 370 380 390 400
380 390 400 410 420 430
pF1KA1 QPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLP
. .:. . ::: ..::. :.::....: .: .::::.. ::. ::: : :
XP_016 SQTNEQSSVWAK--TGGTVESDGSTESTGRLEE-----KGTGESQSRDRRKIDQ-HTLLQ
410 420 430 440 450
440 450 460 470 480 490
pF1KA1 ----RNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGG
:.:::::::::.::::::.::::::. : :::.:::.:::::::: .:::. :::.
XP_016 SIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGA
460 470 480 490 500 510
500 510 520 530 540 550
pF1KA1 KNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAA
: . :...::::::: . :: :::: :. . : : :. ..:..
XP_016 CIDKTSPNGNDTSSVSGWGDPKPA-----LRWGDS--KGSNCQGGWEDDSAATGM-----
520 530 540 550 560
560 570 580 590 600 610
pF1KA1 AKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGD-WADSSSVLGHLG
.::.. : .: .... .:.. : : : :::::.:. .::....: :...: .: :
XP_016 VKSNQ-W---GNCKEEKAAWNDSQKNK-QGWGDGQKSSQGWSVSASDNWGETSRN-NHWG
570 580 590 600 610
620 630 640 650 660 670
pF1KA1 DGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASK
...:..:. .::.:: ::::. .... :::. : : ...: :. :: :.:.:..
XP_016 EANKKSSSGGSDSDRSVSGWNELGKTSSFTWGNNIN--PNNSSGWDESSKPTPSQGWGDP
620 630 640 650 660 670
680 690 700
pF1KA1 PQDNNVSNWGGA-----------------------ASVKQTGTGWIGGPVPVKQKDSSEA
:..:. .:: . :. : ::::.:::.:. :. :
XP_016 PKSNQSLGWGDSSKPVSSPDWNKQQDIVGSWGIPPATGKPPGTGWLGGPIPAPAKEE-EP
680 690 700 710 720 730
710 720 730 740 750 760
pF1KA1 TGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTT
:::::::: :::::::::::::::::::.:: :.::::..: : . .. .
XP_016 TGWEEPSPESIRRKMEIDDGTSAWGDPSKYNYKNVNMWNKNVP----------NGNSRSD
740 750 760 770 780
770 780 790 800 810 820
pF1KA1 TSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPSTLV
. .:.. :: :.. :. : ::::: : :::::.:.: :
XP_016 QQAQVHQLLTP----ASAISNKEASSG------SGWGE-P---------WGEPSTPATTV
790 800 810 820
830 840 850 860 870 880
pF1KA1 DNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMN
::::.::::: .:: .::. : . ... :. .:: : . ::::.:: ::.:
XP_016 DNGTSAWGKPIDSGPSWGEPIAAASSTSTWGSSSVGPQALSKSGPKSMQDGWC--GDDMP
830 840 850 860 870
890 900 910 920
pF1KA1 LSTSQ---WEDEEGDV----WNNAASQESTSSCSSWGNAPKKGLQKG------------M
: .. ::.:: :: ::. .::: .:: . : :: .:: :
XP_016 LPGNRPTGWEEEE-DVEIGMWNSNSSQELNSSLN-WPPYTKKMSSKGLSGKKRRRERGMM
880 890 900 910 920 930
930 940 950 960 970 980
pF1KA1 KTSGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNNMNLDQAMSALLEKKVDVDKRGLG
: ..::.:::: . ..::.....: :. :: ..::.:.:. .: : .:....::..:.
XP_016 KGGNKQEEAWI-NPFVKQFSNISFSRDSPEENVQSNKMDLSGGM--LQDKRMEIDKHSLN
940 950 960 970 980 990
990 1000 1010 1020 1030 1040
pF1KA1 VTDHNGMAAKPLGCRPPISKESSVDRPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSAL
. :.: ..: : :: ::::::..: ..:::: ...: :. : :.::: :.:::
XP_016 IGDYNRTVGKGPGSRPQISKESSMERNPYFDKDGIVADESQNMQFMSSQSMKLPPSNSAL
1000 1010 1020 1030 1040 1050
1050 1060 1070 1080 1090 1100
pF1KA1 PSQALGGIASGLGMQNLNSSRQIPSGNLGMFG-NSGAAQARTMQQPPQPPVQPLNSSQPS
:.::::.:: ::::::::: :: .:: .::: .. ::: : :::: :.:::.::::.
XP_016 PNQALGSIA-GLGMQNLNSVRQ--NGNPSMFGVGNTAAQPRGMQQP---PAQPLSSSQPN
1060 1070 1080 1090 1100
1110 1120 1130 1140 1150 1160
pF1KA1 LRAQVPQ-FLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQLYQL-QLAY----
:::::: .::::: ..::..: .: :::: . .::...::::: :: ::.
XP_016 LRAQVPPPLLSPQVPVSLLKYAPNNGGLNPLF-----GPQQVAMLNQLSQLNQLSQISQL
1110 1120 1130 1140 1150 1160
1170 1180 1190 1200 1210 1220
pF1KA1 QRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPP
::: ::: :.::.: .. : :..: .: .. .:::..:..::: ::::: ::
XP_016 QRLLAQQQRAQSQRSVPSGNRPQQDQQGRPLS-VQQQMMQQSRQLDPNLLVKQQTPPS--
1170 1180 1190 1200 1210 1220
1230 1240 1250 1260 1270 1280
pF1KA1 PHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSP-NTFAPYPLAGLNPNMNVNSMD
. :: : :: .:. :.: :.:: . :: :.:. .:. ::: :.::: ::
XP_016 QQQPLHQPAMKSFLDNV--MPHTT--PELQ---KGPSPINAFSNFPI-GLNSNLNVN-MD
1230 1240 1250 1260 1270
1290 1300 1310 1320 1330 1340
pF1KA1 MTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSI
:. :.:.: :::: .:: ..:.. :. . :.:: :::::: .:. .
XP_016 MN---SIKEP---QSRLRKWT---TVDSI-SVNTSLDQNSSKHGAISSGFRLE-------
1280 1290 1300 1310
1350 1360 1370 1380 1390 1400
pF1KA1 DDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNGSSINWPPEFHPGVPWKGLQN
.. . ::....: :::::: .. .: :::: . ..::.::::::.:: :::: :
XP_016 ESPFVPYDFMNSSTSPASPPGSIGDGWPRAKSPN----GSSSVNWPPEFRPGEPWKGYPN
1320 1330 1340 1350 1360 1370
1410 1420 1430 1440
pF1KA1 IDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGKLSDIKST------WSS-------
::::.:: :::::: .. .::: ...:.. ...:. :....: :::
XP_016 IDPETDPYVTPGSVINNLSINT-VREVDHLRDRNSGSSSSLNTTLPSTSAWSSIRASNYN
1380 1390 1400 1410 1420
1450 1460 1470 1480
pF1KA1 ---------------------GPTSHTQASLSHELWKVP---RNSTAPTRPPPGLTNPKP
.: : :..::.::::::: .: :::.:::::::. ::
XP_016 VPLSSTAQSTSARNSDSKLTWSPGSVTNTSLAHELWKVPLPPKNITAPSRPPPGLTGQKP
1430 1440 1450 1460 1470 1480
1490 1500 1510 1520 1530
pF1KA1 S-STWGASPL----GWTSS---YSSGSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCL
::: ::: :: .: :. ::.:. ..::: ..::::.:::::::::::::::.
XP_016 PLSTWDNSPLRIGGGWGNSDARYTPGSSWGESSSGRITNWLVLKNLTPQIDGSTLRTLCM
1490 1500 1510 1520 1530 1540
1540 1550 1560 1570 1580 1590
pF1KA1 QHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQ
:::::::::::: .:::.::::::::..:::::::::::::::::::::.:::..::.::
XP_016 QHGPLITFHLNLPHGNALVRYSSKEEVVKAQKSLHMCVLGNTTILAEFASEEEISRFFAQ
1550 1560 1570 1580 1590 1600
1600 1610 1620 1630 1640 1650
pF1KA1 GQALPPTSSWQSSSASSQPRLSAAGSSHGLV-RSDAGHWNAPCLGGKGSSEL----LWGG
.:.: :. .::: . ::: ::.. ::.. :.: .:::. :.: . ..: :::
XP_016 SQSLTPSPGWQSLG-SSQSRLGSLDCSHSFSSRTDLNHWNGAGLSGTNCGDLHGTSLWG-
1610 1620 1630 1640 1650 1660
1660 1670 1680 1690
pF1KA1 VPQYSSSLWGPPSADDSRVIGSPTPLTTLLPGDLLSGESL
.:.::.:::::::..: : :.::.:....: : :.:
XP_016 TPHYSTSLWGPPSSSDPRGISSPSPINAFLSVDHLGGGGESM
1670 1680 1690 1700
1690 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 21:27:51 2016 done: Wed Nov 2 21:27:54 2016
Total Scan time: 20.320 Total Display time: 0.900
Function used was FASTA [36.3.4 Apr, 2011]