Result of FASTA (omim) for
pF1KA1597
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1597, 895 aa
1>>>pF1KA1597 895 - 895 aa - 895 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.8144+/-0.000477; mu= -5.8839+/- 0.030
mean_var=252.9135+/-51.559, 0's: 0 Z-trim(116.7): 233 B-trim: 0 in 0/56
Lambda= 0.080647
statistics sampled from 27871 (28120) to 27871 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.676), E-opt: 0.2 (0.33), width: 16
Scan time: 11.600
The best scores are: opt bits E(85289)
NP_116561 (OMIM: 612880) synaptotagmin-like protei ( 910) 5909 701.7 4.1e-201
XP_005274120 (OMIM: 612880) PREDICTED: synaptotagm ( 911) 5897 700.3 1.1e-200
XP_016873427 (OMIM: 612880) PREDICTED: synaptotagm ( 862) 5698 677.1 9.6e-194
XP_005274118 (OMIM: 612880) PREDICTED: synaptotagm ( 950) 3747 450.1 2.3e-125
XP_005274117 (OMIM: 612880) PREDICTED: synaptotagm ( 951) 3735 448.8 5.9e-125
NP_001276537 (OMIM: 612880) synaptotagmin-like pro ( 902) 3536 425.6 5.3e-118
NP_001156423 (OMIM: 612880) synaptotagmin-like pro ( 934) 3423 412.4 4.9e-114
XP_005274123 (OMIM: 612880) PREDICTED: synaptotagm ( 894) 3416 411.6 8.4e-114
NP_001156425 (OMIM: 612880) synaptotagmin-like pro ( 935) 3411 411.1 1.3e-113
XP_016873422 (OMIM: 612880) PREDICTED: synaptotagm (2222) 3128 378.3 2.3e-103
XP_011543408 (OMIM: 612880) PREDICTED: synaptotagm (2238) 3128 378.3 2.3e-103
XP_011543414 (OMIM: 612880) PREDICTED: synaptotagm (1828) 3116 376.9 5e-103
XP_016873424 (OMIM: 612880) PREDICTED: synaptotagm (2171) 3116 376.9 5.8e-103
XP_011543412 (OMIM: 612880) PREDICTED: synaptotagm (2182) 3116 376.9 5.9e-103
XP_005274114 (OMIM: 612880) PREDICTED: synaptotagm (2223) 3116 376.9 6e-103
XP_011543407 (OMIM: 612880) PREDICTED: synaptotagm (2239) 3116 376.9 6e-103
XP_005274119 (OMIM: 612880) PREDICTED: synaptotagm ( 924) 3098 374.6 1.2e-102
XP_016873426 (OMIM: 612880) PREDICTED: synaptotagm ( 876) 3096 374.4 1.3e-102
XP_011543411 (OMIM: 612880) PREDICTED: synaptotagm (2190) 2917 353.7 5.5e-96
XP_011543410 (OMIM: 612880) PREDICTED: synaptotagm (2199) 2859 347.0 5.9e-94
XP_016873423 (OMIM: 612880) PREDICTED: synaptotagm (2211) 2491 304.2 4.6e-81
XP_011543409 (OMIM: 612880) PREDICTED: synaptotagm (2212) 2479 302.8 1.2e-80
XP_016873425 (OMIM: 612880) PREDICTED: synaptotagm (2096) 2294 281.2 3.5e-74
NP_001156424 (OMIM: 612880) synaptotagmin-like pro ( 336) 2239 274.5 6e-73
NP_001276539 (OMIM: 612880) synaptotagmin-like pro ( 336) 2239 274.5 6e-73
XP_016873429 (OMIM: 612880) PREDICTED: synaptotagm ( 429) 2194 269.3 2.8e-71
XP_016873428 (OMIM: 612880) PREDICTED: synaptotagm ( 445) 2192 269.1 3.4e-71
XP_011543416 (OMIM: 612880) PREDICTED: synaptotagm ( 365) 2175 267.1 1.1e-70
NP_996813 (OMIM: 612880) synaptotagmin-like protei ( 365) 2175 267.1 1.1e-70
NP_996812 (OMIM: 612880) synaptotagmin-like protei ( 376) 2175 267.1 1.1e-70
XP_005274124 (OMIM: 612880) PREDICTED: synaptotagm ( 376) 2175 267.1 1.1e-70
XP_011543418 (OMIM: 612880) PREDICTED: synaptotagm ( 325) 2162 265.5 2.9e-70
XP_011543417 (OMIM: 612880) PREDICTED: synaptotagm ( 325) 2162 265.5 2.9e-70
NP_001276538 (OMIM: 612880) synaptotagmin-like pro ( 255) 1717 213.7 9e-55
NP_116261 (OMIM: 608042) synaptotagmin-like protei ( 550) 1110 143.2 3.2e-33
XP_006711053 (OMIM: 608042) PREDICTED: synaptotagm ( 582) 1110 143.2 3.4e-33
NP_001180237 (OMIM: 608042) synaptotagmin-like pro ( 562) 1102 142.3 6.2e-33
XP_005246079 (OMIM: 608042) PREDICTED: synaptotagm ( 594) 1102 142.3 6.5e-33
NP_001167539 (OMIM: 300723) synaptotagmin-like pro ( 671) 975 127.6 2e-28
NP_001123368 (OMIM: 300723) synaptotagmin-like pro ( 671) 975 127.6 2e-28
NP_542775 (OMIM: 300723) synaptotagmin-like protei ( 671) 975 127.6 2e-28
XP_005262286 (OMIM: 300723) PREDICTED: synaptotagm ( 671) 975 127.6 2e-28
XP_011529370 (OMIM: 300723) PREDICTED: synaptotagm ( 671) 975 127.6 2e-28
XP_016885460 (OMIM: 300723) PREDICTED: synaptotagm ( 671) 975 127.6 2e-28
XP_006711054 (OMIM: 608042) PREDICTED: synaptotagm ( 355) 927 121.9 5.6e-27
XP_016885455 (OMIM: 300723) PREDICTED: synaptotagm ( 676) 809 108.3 1.3e-22
XP_016885456 (OMIM: 300723) PREDICTED: synaptotagm ( 676) 809 108.3 1.3e-22
XP_016885459 (OMIM: 300723) PREDICTED: synaptotagm ( 676) 809 108.3 1.3e-22
XP_016885458 (OMIM: 300723) PREDICTED: synaptotagm ( 676) 809 108.3 1.3e-22
XP_016885457 (OMIM: 300723) PREDICTED: synaptotagm ( 676) 809 108.3 1.3e-22
>>NP_116561 (OMIM: 612880) synaptotagmin-like protein 2 (910 aa)
initn: 5909 init1: 5909 opt: 5909 Z-score: 3731.6 bits: 701.7 E(85289): 4.1e-201
Smith-Waterman score: 5909; 99.9% identity (100.0% similar) in 895 aa overlap (1-895:16-910)
10 20 30 40
pF1KA1 MKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK
:::::::::::::::::::::::::::::::::::::::::::::
NP_116 MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA1 RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTKNEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTKNEQ
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 SKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 SKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKM
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA1 IYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 IYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKIV
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA1 SPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 SPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLE
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 SDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 SDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGL
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA1 HSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 HSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGGS
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA1 SRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 SRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDDE
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA1 KPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQDEVSGSVMSVYSGDFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 KPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQDEVSGSVMSVYSGDFG
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA1 NLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 NLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKK
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA1 TLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 TLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDN
670 680 690 700 710 720
710 720 730 740 750 760
pF1KA1 KQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 KQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDL
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA1 PLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEVCVEL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
NP_116 PLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVEL
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA1 TVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 TVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPL
850 860 870 880 890 900
890
pF1KA1 RMLLIAKISK
::::::::::
NP_116 RMLLIAKISK
910
>>XP_005274120 (OMIM: 612880) PREDICTED: synaptotagmin-l (911 aa)
initn: 4979 init1: 4979 opt: 5897 Z-score: 3724.1 bits: 700.3 E(85289): 1.1e-200
Smith-Waterman score: 5897; 99.8% identity (99.9% similar) in 896 aa overlap (1-895:16-911)
10 20 30 40
pF1KA1 MKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK
:::::::::::::::::::::::::::::::::::::::::::::
XP_005 MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA1 RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEK-RKNPFNSSKLPEGHSSQQTKNE
::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
XP_005 EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEKQRKNPFNSSKLPEGHSSQQTKNE
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 QSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARK
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA1 MIYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MIYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKI
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA1 VSPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVL
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 ESDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPING
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPING
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA1 LHSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGG
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA1 SSRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDD
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA1 EKPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQDEVSGSVMSVYSGDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQDEVSGSVMSVYSGDF
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA1 GNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKK
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA1 KTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWD
670 680 690 700 710 720
710 720 730 740 750 760
pF1KA1 NKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLD
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA1 LPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEVCVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
XP_005 LPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVE
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA1 LTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLP
850 860 870 880 890 900
890
pF1KA1 LRMLLIAKISK
:::::::::::
XP_005 LRMLLIAKISK
910
>>XP_016873427 (OMIM: 612880) PREDICTED: synaptotagmin-l (862 aa)
initn: 5698 init1: 5698 opt: 5698 Z-score: 3599.3 bits: 677.1 E(85289): 9.6e-194
Smith-Waterman score: 5698; 99.9% identity (100.0% similar) in 862 aa overlap (34-895:1-862)
10 20 30 40 50 60
pF1KA1 LQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAKRHRDKIHGADIIRASMRK
::::::::::::::::::::::::::::::
XP_016 MSGQWFYEAKAKRHRDKIHGADIIRASMRK
10 20 30
70 80 90 100 110 120
pF1KA1 KRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEPEEDAAPASPSSSVVNPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEPEEDAAPASPSSSVVNPAS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KA1 SVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTKNEQSKNGRTGLFQTSKEDELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTKNEQSKNGRTGLFQTSKEDELS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KA1 ESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKMIYKSTDLNKDDNQSFPRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKMIYKSTDLNKDDNQSFPRQ
160 170 180 190 200 210
250 260 270 280 290 300
pF1KA1 RTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKIVSPGLTIHERISEKEHSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKIVSPGLTIHERISEKEHSLE
220 230 240 250 260 270
310 320 330 340 350 360
pF1KA1 DNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLESDRLKNGMEDAGDTEEFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLESDRLKNGMEDAGDTEEFQ
280 290 300 310 320 330
370 380 390 400 410 420
pF1KA1 SDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGLHSHSEVLTARPQSMENSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGLHSHSEVLTARPQSMENSP
340 350 360 370 380 390
430 440 450 460 470 480
pF1KA1 TINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGGSSRDRQQGSEEEPSPVLKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGGSSRDRQQGSEEEPSPVLKT
400 410 420 430 440 450
490 500 510 520 530 540
pF1KA1 LERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDDEKPDQKPVTNECVPRISTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDDEKPDQKPVTNECVPRISTV
460 470 480 490 500 510
550 560 570 580 590 600
pF1KA1 PTQPDNPFSHPDKLKRMSKSVPAFLQDEVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTQPDNPFSHPDKLKRMSKSVPAFLQDEVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESL
520 530 540 550 560 570
610 620 630 640 650 660
pF1KA1 KELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRY
580 590 600 610 620 630
670 680 690 700 710 720
pF1KA1 KIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPV
640 650 660 670 680 690
730 740 750 760 770 780
pF1KA1 ALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILP
700 710 720 730 740 750
790 800 810 820 830 840
pF1KA1 DTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEVCVELTVWDHYKLTNQFLGGLRI
:::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::
XP_016 DTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRI
760 770 780 790 800 810
850 860 870 880 890
pF1KA1 GFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK
820 830 840 850 860
>>XP_005274118 (OMIM: 612880) PREDICTED: synaptotagmin-l (950 aa)
initn: 5895 init1: 3747 opt: 3747 Z-score: 2371.8 bits: 450.1 E(85289): 2.3e-125
Smith-Waterman score: 5777; 95.6% identity (95.7% similar) in 927 aa overlap (1-887:16-942)
10 20 30 40
pF1KA1 MKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK
:::::::::::::::::::::::::::::::::::::::::::::
XP_005 MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA1 RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTKNEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTKNEQ
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 SKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKM
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA1 IYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKIV
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA1 SPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLE
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 SDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGL
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA1 HSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGGS
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA1 SRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDDE
490 500 510 520 530 540
530 540 550 560 570
pF1KA1 KPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQDE--------------
::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSY
550 560 570 580 590 600
580 590 600
pF1KA1 --------------------------VSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKE
::::::::::::::::::::::::::::::::::
XP_005 QLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKE
610 620 630 640 650 660
610 620 630 640 650 660
pF1KA1 LHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKI
670 680 690 700 710 720
670 680 690 700 710 720
pF1KA1 EKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVAL
730 740 750 760 770 780
730 740 750 760 770 780
pF1KA1 EAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDT
790 800 810 820 830 840
790 800 810 820 830 840
pF1KA1 SRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEVCVELTVWDHYKLTNQFLGGLRIGF
:::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::
XP_005 SRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGF
850 860 870 880 890 900
850 860 870 880 890
pF1KA1 GTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK
::::::::::::::::::::::::::::::::::::::::::
XP_005 GTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK
910 920 930 940 950
>>XP_005274117 (OMIM: 612880) PREDICTED: synaptotagmin-l (951 aa)
initn: 4965 init1: 2817 opt: 3735 Z-score: 2364.3 bits: 448.8 E(85289): 5.9e-125
Smith-Waterman score: 5765; 95.5% identity (95.6% similar) in 928 aa overlap (1-887:16-943)
10 20 30 40
pF1KA1 MKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK
:::::::::::::::::::::::::::::::::::::::::::::
XP_005 MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA1 RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEK-RKNPFNSSKLPEGHSSQQTKNE
::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
XP_005 EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEKQRKNPFNSSKLPEGHSSQQTKNE
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 QSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARK
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA1 MIYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MIYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKI
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA1 VSPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVL
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 ESDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPING
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPING
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA1 LHSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGG
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA1 SSRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDD
490 500 510 520 530 540
530 540 550 560 570
pF1KA1 EKPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQDE-------------
:::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESS
550 560 570 580 590 600
580 590 600
pF1KA1 ---------------------------VSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLK
:::::::::::::::::::::::::::::::::
XP_005 YQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLK
610 620 630 640 650 660
610 620 630 640 650 660
pF1KA1 ELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYK
670 680 690 700 710 720
670 680 690 700 710 720
pF1KA1 IEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVA
730 740 750 760 770 780
730 740 750 760 770 780
pF1KA1 LEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPD
790 800 810 820 830 840
790 800 810 820 830 840
pF1KA1 TSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEVCVELTVWDHYKLTNQFLGGLRIG
::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
XP_005 TSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIG
850 860 870 880 890 900
850 860 870 880 890
pF1KA1 FGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK
:::::::::::::::::::::::::::::::::::::::::::
XP_005 FGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK
910 920 930 940 950
>>NP_001276537 (OMIM: 612880) synaptotagmin-like protein (902 aa)
initn: 5684 init1: 3536 opt: 3536 Z-score: 2239.5 bits: 425.6 E(85289): 5.3e-118
Smith-Waterman score: 5566; 95.4% identity (95.5% similar) in 894 aa overlap (34-887:1-894)
10 20 30 40 50 60
pF1KA1 LQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAKRHRDKIHGADIIRASMRK
::::::::::::::::::::::::::::::
NP_001 MSGQWFYEAKAKRHRDKIHGADIIRASMRK
10 20 30
70 80 90 100 110 120
pF1KA1 KRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEPEEDAAPASPSSSVVNPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEPEEDAAPASPSSSVVNPAS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KA1 SVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTKNEQSKNGRTGLFQTSKEDELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTKNEQSKNGRTGLFQTSKEDELS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KA1 ESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKMIYKSTDLNKDDNQSFPRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKMIYKSTDLNKDDNQSFPRQ
160 170 180 190 200 210
250 260 270 280 290 300
pF1KA1 RTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKIVSPGLTIHERISEKEHSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKIVSPGLTIHERISEKEHSLE
220 230 240 250 260 270
310 320 330 340 350 360
pF1KA1 DNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLESDRLKNGMEDAGDTEEFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLESDRLKNGMEDAGDTEEFQ
280 290 300 310 320 330
370 380 390 400 410 420
pF1KA1 SDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGLHSHSEVLTARPQSMENSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGLHSHSEVLTARPQSMENSP
340 350 360 370 380 390
430 440 450 460 470 480
pF1KA1 TINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGGSSRDRQQGSEEEPSPVLKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGGSSRDRQQGSEEEPSPVLKT
400 410 420 430 440 450
490 500 510 520 530 540
pF1KA1 LERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDDEKPDQKPVTNECVPRISTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDDEKPDQKPVTNECVPRISTV
460 470 480 490 500 510
550 560 570
pF1KA1 PTQPDNPFSHPDKLKRMSKSVPAFLQDE--------------------------------
::::::::::::::::::::::::::::
NP_001 PTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSS
520 530 540 550 560 570
580 590 600 610 620
pF1KA1 --------VSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKK
580 590 600 610 620 630
630 640 650 660 670 680
pF1KA1 QRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRD
640 650 660 670 680 690
690 700 710 720 730 740
pF1KA1 TFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEP
700 710 720 730 740 750
750 760 770 780 790 800
pF1KA1 VPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPI
760 770 780 790 800 810
810 820 830 840 850 860
pF1KA1 FNHTMVYDGFRPEDLMEVCVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSE
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
NP_001 FNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSE
820 830 840 850 860 870
870 880 890
pF1KA1 EVALWEKMVNSPNTWIEATLPLRMLLIAKISK
::::::::::::::::::::::::
NP_001 EVALWEKMVNSPNTWIEATLPLRMLLIAKISK
880 890 900
>>NP_001156423 (OMIM: 612880) synaptotagmin-like protein (934 aa)
initn: 5761 init1: 3409 opt: 3423 Z-score: 2168.2 bits: 412.4 E(85289): 4.9e-114
Smith-Waterman score: 5657; 93.8% identity (94.0% similar) in 935 aa overlap (1-895:16-934)
10 20 30 40
pF1KA1 MKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA1 RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTKNEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTKNEQ
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 SKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKM
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA1 IYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKIV
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA1 SPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLE
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 SDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGL
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA1 HSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGGS
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA1 SRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAED--
490 500 510 520 530
530 540 550 560 570
pF1KA1 KPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQDE--------------
.:::::::::::::::::::::::::::::::
NP_001 --------------VSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSY
540 550 560 570 580
580 590 600
pF1KA1 --------------------------VSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKE
::::::::::::::::::::::::::::::::::
NP_001 QLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKE
590 600 610 620 630 640
610 620 630 640 650 660
pF1KA1 LHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKI
650 660 670 680 690 700
670 680 690 700 710 720
pF1KA1 EKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVAL
710 720 730 740 750 760
730 740 750 760 770 780
pF1KA1 EAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDT
770 780 790 800 810 820
790 800 810 820 830 840
pF1KA1 SRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEVCVELTVWDHYKLTNQFLGGLRIGF
:::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::
NP_001 SRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGF
830 840 850 860 870 880
850 860 870 880 890
pF1KA1 GTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK
890 900 910 920 930
>>XP_005274123 (OMIM: 612880) PREDICTED: synaptotagmin-l (894 aa)
initn: 3499 init1: 3410 opt: 3416 Z-score: 2164.1 bits: 411.6 E(85289): 8.4e-114
Smith-Waterman score: 5747; 98.0% identity (98.2% similar) in 895 aa overlap (1-895:16-894)
10 20 30 40
pF1KA1 MKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK
:::::::::::::::::::::::::::::::::::::::::::::
XP_005 MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA1 RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTKNEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTKNEQ
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 SKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKM
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA1 IYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKIV
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA1 SPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLE
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 SDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGL
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA1 HSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGGS
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA1 SRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAED--
490 500 510 520 530
530 540 550 560 570 580
pF1KA1 KPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQDEVSGSVMSVYSGDFG
.:::::::::::::::::::::::::::::::::::::::::::::
XP_005 --------------VSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDEVSGSVMSVYSGDFG
540 550 560 570 580
590 600 610 620 630 640
pF1KA1 NLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKK
590 600 610 620 630 640
650 660 670 680 690 700
pF1KA1 TLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDN
650 660 670 680 690 700
710 720 730 740 750 760
pF1KA1 KQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDL
710 720 730 740 750 760
770 780 790 800 810 820
pF1KA1 PLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEVCVEL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
XP_005 PLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVEL
770 780 790 800 810 820
830 840 850 860 870 880
pF1KA1 TVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPL
830 840 850 860 870 880
890
pF1KA1 RMLLIAKISK
::::::::::
XP_005 RMLLIAKISK
890
>>NP_001156425 (OMIM: 612880) synaptotagmin-like protein (935 aa)
initn: 4831 init1: 2479 opt: 3411 Z-score: 2160.7 bits: 411.1 E(85289): 1.3e-113
Smith-Waterman score: 5645; 93.7% identity (93.9% similar) in 936 aa overlap (1-895:16-935)
10 20 30 40
pF1KA1 MKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA1 RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEK-RKNPFNSSKLPEGHSSQQTKNE
::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
NP_001 EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEKQRKNPFNSSKLPEGHSSQQTKNE
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 QSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARK
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA1 MIYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKI
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA1 VSPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVL
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 ESDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPING
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPING
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA1 LHSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGG
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA1 SSRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAED-
490 500 510 520 530
530 540 550 560 570
pF1KA1 EKPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQDE-------------
.:::::::::::::::::::::::::::::::
NP_001 ---------------VSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESS
540 550 560 570 580
580 590 600
pF1KA1 ---------------------------VSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLK
:::::::::::::::::::::::::::::::::
NP_001 YQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLK
590 600 610 620 630 640
610 620 630 640 650 660
pF1KA1 ELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYK
650 660 670 680 690 700
670 680 690 700 710 720
pF1KA1 IEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVA
710 720 730 740 750 760
730 740 750 760 770 780
pF1KA1 LEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPD
770 780 790 800 810 820
790 800 810 820 830 840
pF1KA1 TSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEVCVELTVWDHYKLTNQFLGGLRIG
::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
NP_001 TSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIG
830 840 850 860 870 880
850 860 870 880 890
pF1KA1 FGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK
890 900 910 920 930
>>XP_016873422 (OMIM: 612880) PREDICTED: synaptotagmin-l (2222 aa)
initn: 5747 init1: 3094 opt: 3128 Z-score: 1976.8 bits: 378.3 E(85289): 2.3e-103
Smith-Waterman score: 3133; 83.3% identity (90.6% similar) in 604 aa overlap (1-590:16-611)
10 20 30 40
pF1KA1 MKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA1 RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTKNEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTKNEQ
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 SKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKM
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA1 IYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKIV
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA1 SPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLE
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 SDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGL
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA1 HSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGGS
430 440 450 460 470 480
470 480 490 500 510
pF1KA1 SRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSS--------NQAKVDNQPEEL
::::::: . : :.::. ....:. : . :.:.: :... ... . .
XP_016 SRDRQQG-KPPPLPALKA--KTSSRSGPYATEIKKSTDDSIFKVLDWFNRSSYSDDNKSF
490 500 510 520 530
520 530 540 550 560 570
pF1KA1 V---RSAEDDEKPDQKP-VTNECVPRISTVPTQPDNPFSHPDK--LKRMSKSVPAFLQDE
. :. :. :: :.: :. . : .:. . .. .: :.: :: . .. : .: :
XP_016 LQHPRGIESKEKTDSKSQVAVDLVTDDTTLRENGSKTLS-PSKIELKPVRSDSP--FQAE
540 550 560 570 580 590
580 590 600 610 620 630
pF1KA1 VSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVK
:... : . .:...:
XP_016 --GDMLVSESCQDNNVNIKSKFMNLSQKGTPKEGPGILQPFESYGTPSQGSKNMDYSQDS
600 610 620 630 640 650
>--
initn: 2696 init1: 2162 opt: 2213 Z-score: 1401.5 bits: 271.8 E(85289): 2.5e-71
Smith-Waterman score: 2625; 53.0% identity (68.8% similar) in 924 aa overlap (43-895:1341-2222)
20 30 40 50 60 70
pF1KA1 AEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAKRHRDKIHGADIIRASMRKKRPQIAAEQ
.:. : .. . .. .. . :: . .
XP_016 TSQLSRKGSFGDVASPPQDMLFPQDAHLVPQARVHPSQTEISETVEKVILPPRP-VLNDV
1320 1330 1340 1350 1360
80 90 100 110 120
pF1KA1 SKDRENGAKESWVNNVNKDAFLPPELAGVVEEPEEDAAPASPSS--SVVNPASSV--IDM
: .. : :.. : :. : :: :: . .:..: ... :
XP_016 SAALQKLCGEVWLSYPAGREVGPGEVNP--EFPEAVQPVCSPLNPPGVISPWATMDTIVP
1370 1380 1390 1400 1410 1420
130 140 150 160 170 180
pF1KA1 SQENTRKPNVSPEKRKN--PFNSSKL-PEGHSSQQTKNEQSKNGRTGLFQTSKE---DEL
.... . :: :.: .. . .... : .. .. . .. :. :: : .: . .
XP_016 DRKDFYSSNVVPDKTHEVGSYLAAQMSPSDQTLSSFASIVAQYGK-GLPQEVEEIVRETI
1430 1440 1450 1460 1470 1480
190 200 210 220 230 240
pF1KA1 SESKEKSTVADTSIQKLEKSK-QTLPGLSNGSQIKAPIPKARKMIYKSTDLNKDDNQSFP
. : . .....:: : . .:.:. . :. :. :.: .. . . .. :
XP_016 VQPKSEFLEFSAGLEKLLKEETETFPS-KYESDTGNLSPS--KLIGSTEEPRRATSECHP
1490 1500 1510 1520 1530 1540
250 260 270 280 290 300
pF1KA1 RQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKIVSPGLTIHERISEKEHS
.. .... :: : .:. .. . :. . : .: ....:. ::: :
XP_016 EELKETVEKAEAP---LITESAFDAGFEKLLKEITEAPP----YQPQVSVREETHEKESS
1550 1560 1570 1580 1590
310 320 330 340 350 360
pF1KA1 LEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLESDRLKNGMEDAGDTE-
... . : . : ... .: :: : .: . :.. .: :: :.
XP_016 QSEQTRFLGTVPHFYRAASQTSEMKDKSNGL-------ESQVNQCDKMLGG--DALVTDL
1600 1610 1620 1630 1640
370 380 390 400 410
pF1KA1 --EFQSDPKPSQY-RKPSLF--HQ-----STSSPYVSKSETHQPMTSGSFPINGLHSHSE
.: .. . . : :.:. :. ... : ::. .:.. :. ::
XP_016 LVDFCGSRSGVEIPRTPQLYVAHEIGTIKTVTPPEDRDSESGVAGGQGTLQEPGFGEASE
1650 1660 1670 1680 1690 1700
420 430 440 450 460
pF1KA1 VLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPE---PSQVPGGSSR
.... .. . : . . :..:.. ...: .: :: . . : : :. :..
XP_016 AISVS-RNRQPIPLLMN-KENSTKTSKVELTLA-SPYMKQEKEEEKEGFSESDFSDGNTS
1710 1720 1730 1740 1750 1760
470 480 490 500 510 520
pF1KA1 DRQQG------SEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSA
. .. :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNAESWRNPSSSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSA
1770 1780 1790 1800 1810 1820
530 540 550 560 570
pF1KA1 EDDEKPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQDE----------
:: .:::::::::::::::::::::::::::::::
XP_016 ED----------------VSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTAS
1830 1840 1850 1860
580 590 600
pF1KA1 ------------------------------VSGSVMSVYSGDFGNLEVKGNIQFAIEYVE
::::::::::::::::::::::::::::::
XP_016 ESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVE
1870 1880 1890 1900 1910 1920
610 620 630 640 650 660
pF1KA1 SLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEIL
1930 1940 1950 1960 1970 1980
670 680 690 700 710 720
pF1KA1 RYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTA
1990 2000 2010 2020 2030 2040
730 740 750 760 770 780
pF1KA1 PVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTI
2050 2060 2070 2080 2090 2100
790 800 810 820 830 840
pF1KA1 LPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEVCVELTVWDHYKLTNQFLGGL
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_016 LPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGL
2110 2120 2130 2140 2150 2160
850 860 870 880 890
pF1KA1 RIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK
2170 2180 2190 2200 2210 2220
895 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 21:30:47 2016 done: Wed Nov 2 21:30:49 2016
Total Scan time: 11.600 Total Display time: 0.310
Function used was FASTA [36.3.4 Apr, 2011]