FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1598, 631 aa 1>>>pF1KA1598 631 - 631 aa - 631 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.5288+/-0.00108; mu= -10.2095+/- 0.065 mean_var=454.6522+/-95.131, 0's: 0 Z-trim(115.4): 24 B-trim: 140 in 1/52 Lambda= 0.060150 statistics sampled from 15977 (15992) to 15977 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.759), E-opt: 0.2 (0.491), width: 16 Scan time: 3.070 The best scores are: opt bits E(32554) CCDS44482.1 SHTN1 gene_id:57698|Hs108|chr10 ( 631) 4025 363.6 4.5e-100 CCDS73207.1 SHTN1 gene_id:57698|Hs108|chr10 ( 571) 3647 330.8 3.1e-90 CCDS73208.1 SHTN1 gene_id:57698|Hs108|chr10 ( 558) 3528 320.4 3.9e-87 CCDS58097.1 SHTN1 gene_id:57698|Hs108|chr10 ( 498) 3150 287.6 2.7e-77 CCDS31293.1 SHTN1 gene_id:57698|Hs108|chr10 ( 456) 2878 264.0 3.2e-70 >>CCDS44482.1 SHTN1 gene_id:57698|Hs108|chr10 (631 aa) initn: 4025 init1: 4025 opt: 4025 Z-score: 1910.1 bits: 363.6 E(32554): 4.5e-100 Smith-Waterman score: 4025; 100.0% identity (100.0% similar) in 631 aa overlap (1-631:1-631) 10 20 30 40 50 60 pF1KA1 MNSSDEEKQLQLITSLKEQAIGEYEDLRAENQKTKEKCDKIRQERDEAVKKLEEFQKISH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MNSSDEEKQLQLITSLKEQAIGEYEDLRAENQKTKEKCDKIRQERDEAVKKLEEFQKISH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 MVIEEVNFMQNHLEIEKTCRESAEALATKLNKENKTLKRISMLYMAKLGPDVITEEINID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MVIEEVNFMQNHLEIEKTCRESAEALATKLNKENKTLKRISMLYMAKLGPDVITEEINID 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 DEDSTTDTDGAAETCVSVQCQKQIKELRDQIVSVQEEKKILAIELENLKSKLVEVIEEVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 DEDSTTDTDGAAETCVSVQCQKQIKELRDQIVSVQEEKKILAIELENLKSKLVEVIEEVN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 KVKQEKTVLNSEVLEQRKVLEKCNRVSMLAVEEYEEMQVNLELEKDLRKKAESFAQEMFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KVKQEKTVLNSEVLEQRKVLEKCNRVSMLAVEEYEEMQVNLELEKDLRKKAESFAQEMFI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 EQNKLKRQSHLLLQSSIPDQQLLKALDENAKLTQQLEEERIQHQQKVKELEEQLENETLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 EQNKLKRQSHLLLQSSIPDQQLLKALDENAKLTQQLEEERIQHQQKVKELEEQLENETLH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 KEIHNLKQQLELLEEDKKELELKYQNSEEKARNLKHSVDELQKRVNQSENSVPPPPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KEIHNLKQQLELLEEDKKELELKYQNSEEKARNLKHSVDELQKRVNQSENSVPPPPPPPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 PLPPPPPNPIRSLMSMIRKRSHPSGSGAKKEKATQPETTEEVTDLKRQAVEEMMDRIKKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 PLPPPPPNPIRSLMSMIRKRSHPSGSGAKKEKATQPETTEEVTDLKRQAVEEMMDRIKKG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 VHLRPVNQTARPKTKPESSKGCESAVDELKGILGTLNKSTSSRSLKSLDPENSETELERI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 VHLRPVNQTARPKTKPESSKGCESAVDELKGILGTLNKSTSSRSLKSLDPENSETELERI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 LRRRKVTAEADSSSPTGILATSESKSMPVLGSVSSVTKTALNKKTLEAEFNSPSPPTPEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LRRRKVTAEADSSSPTGILATSESKSMPVLGSVSSVTKTALNKKTLEAEFNSPSPPTPEP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 GEGPRKLEGCTSSKVTFQPPSSIGCRKKYIDGEKQAEPVVVLDPVSTHEPQTKDQVAEKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GEGPRKLEGCTSSKVTFQPPSSIGCRKKYIDGEKQAEPVVVLDPVSTHEPQTKDQVAEKD 550 560 570 580 590 600 610 620 630 pF1KA1 PTQHKEDEGEIQPENKEDSIENVRETDSSNC ::::::::::::::::::::::::::::::: CCDS44 PTQHKEDEGEIQPENKEDSIENVRETDSSNC 610 620 630 >>CCDS73207.1 SHTN1 gene_id:57698|Hs108|chr10 (571 aa) initn: 3647 init1: 3647 opt: 3647 Z-score: 1733.4 bits: 330.8 E(32554): 3.1e-90 Smith-Waterman score: 3647; 100.0% identity (100.0% similar) in 571 aa overlap (61-631:1-571) 40 50 60 70 80 90 pF1KA1 NQKTKEKCDKIRQERDEAVKKLEEFQKISHMVIEEVNFMQNHLEIEKTCRESAEALATKL :::::::::::::::::::::::::::::: CCDS73 MVIEEVNFMQNHLEIEKTCRESAEALATKL 10 20 30 100 110 120 130 140 150 pF1KA1 NKENKTLKRISMLYMAKLGPDVITEEINIDDEDSTTDTDGAAETCVSVQCQKQIKELRDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 NKENKTLKRISMLYMAKLGPDVITEEINIDDEDSTTDTDGAAETCVSVQCQKQIKELRDQ 40 50 60 70 80 90 160 170 180 190 200 210 pF1KA1 IVSVQEEKKILAIELENLKSKLVEVIEEVNKVKQEKTVLNSEVLEQRKVLEKCNRVSMLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 IVSVQEEKKILAIELENLKSKLVEVIEEVNKVKQEKTVLNSEVLEQRKVLEKCNRVSMLA 100 110 120 130 140 150 220 230 240 250 260 270 pF1KA1 VEEYEEMQVNLELEKDLRKKAESFAQEMFIEQNKLKRQSHLLLQSSIPDQQLLKALDENA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 VEEYEEMQVNLELEKDLRKKAESFAQEMFIEQNKLKRQSHLLLQSSIPDQQLLKALDENA 160 170 180 190 200 210 280 290 300 310 320 330 pF1KA1 KLTQQLEEERIQHQQKVKELEEQLENETLHKEIHNLKQQLELLEEDKKELELKYQNSEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 KLTQQLEEERIQHQQKVKELEEQLENETLHKEIHNLKQQLELLEEDKKELELKYQNSEEK 220 230 240 250 260 270 340 350 360 370 380 390 pF1KA1 ARNLKHSVDELQKRVNQSENSVPPPPPPPPPLPPPPPNPIRSLMSMIRKRSHPSGSGAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 ARNLKHSVDELQKRVNQSENSVPPPPPPPPPLPPPPPNPIRSLMSMIRKRSHPSGSGAKK 280 290 300 310 320 330 400 410 420 430 440 450 pF1KA1 EKATQPETTEEVTDLKRQAVEEMMDRIKKGVHLRPVNQTARPKTKPESSKGCESAVDELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 EKATQPETTEEVTDLKRQAVEEMMDRIKKGVHLRPVNQTARPKTKPESSKGCESAVDELK 340 350 360 370 380 390 460 470 480 490 500 510 pF1KA1 GILGTLNKSTSSRSLKSLDPENSETELERILRRRKVTAEADSSSPTGILATSESKSMPVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 GILGTLNKSTSSRSLKSLDPENSETELERILRRRKVTAEADSSSPTGILATSESKSMPVL 400 410 420 430 440 450 520 530 540 550 560 570 pF1KA1 GSVSSVTKTALNKKTLEAEFNSPSPPTPEPGEGPRKLEGCTSSKVTFQPPSSIGCRKKYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 GSVSSVTKTALNKKTLEAEFNSPSPPTPEPGEGPRKLEGCTSSKVTFQPPSSIGCRKKYI 460 470 480 490 500 510 580 590 600 610 620 630 pF1KA1 DGEKQAEPVVVLDPVSTHEPQTKDQVAEKDPTQHKEDEGEIQPENKEDSIENVRETDSSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 DGEKQAEPVVVLDPVSTHEPQTKDQVAEKDPTQHKEDEGEIQPENKEDSIENVRETDSSN 520 530 540 550 560 570 pF1KA1 C : CCDS73 C >>CCDS73208.1 SHTN1 gene_id:57698|Hs108|chr10 (558 aa) initn: 3528 init1: 3528 opt: 3528 Z-score: 1677.8 bits: 320.4 E(32554): 3.9e-87 Smith-Waterman score: 3528; 100.0% identity (100.0% similar) in 558 aa overlap (1-558:1-558) 10 20 30 40 50 60 pF1KA1 MNSSDEEKQLQLITSLKEQAIGEYEDLRAENQKTKEKCDKIRQERDEAVKKLEEFQKISH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 MNSSDEEKQLQLITSLKEQAIGEYEDLRAENQKTKEKCDKIRQERDEAVKKLEEFQKISH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 MVIEEVNFMQNHLEIEKTCRESAEALATKLNKENKTLKRISMLYMAKLGPDVITEEINID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 MVIEEVNFMQNHLEIEKTCRESAEALATKLNKENKTLKRISMLYMAKLGPDVITEEINID 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 DEDSTTDTDGAAETCVSVQCQKQIKELRDQIVSVQEEKKILAIELENLKSKLVEVIEEVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 DEDSTTDTDGAAETCVSVQCQKQIKELRDQIVSVQEEKKILAIELENLKSKLVEVIEEVN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 KVKQEKTVLNSEVLEQRKVLEKCNRVSMLAVEEYEEMQVNLELEKDLRKKAESFAQEMFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 KVKQEKTVLNSEVLEQRKVLEKCNRVSMLAVEEYEEMQVNLELEKDLRKKAESFAQEMFI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 EQNKLKRQSHLLLQSSIPDQQLLKALDENAKLTQQLEEERIQHQQKVKELEEQLENETLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 EQNKLKRQSHLLLQSSIPDQQLLKALDENAKLTQQLEEERIQHQQKVKELEEQLENETLH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 KEIHNLKQQLELLEEDKKELELKYQNSEEKARNLKHSVDELQKRVNQSENSVPPPPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 KEIHNLKQQLELLEEDKKELELKYQNSEEKARNLKHSVDELQKRVNQSENSVPPPPPPPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 PLPPPPPNPIRSLMSMIRKRSHPSGSGAKKEKATQPETTEEVTDLKRQAVEEMMDRIKKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 PLPPPPPNPIRSLMSMIRKRSHPSGSGAKKEKATQPETTEEVTDLKRQAVEEMMDRIKKG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 VHLRPVNQTARPKTKPESSKGCESAVDELKGILGTLNKSTSSRSLKSLDPENSETELERI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 VHLRPVNQTARPKTKPESSKGCESAVDELKGILGTLNKSTSSRSLKSLDPENSETELERI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 LRRRKVTAEADSSSPTGILATSESKSMPVLGSVSSVTKTALNKKTLEAEFNSPSPPTPEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 LRRRKVTAEADSSSPTGILATSESKSMPVLGSVSSVTKTALNKKTLEAEFNSPSPPTPEP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 GEGPRKLEGCTSSKVTFQPPSSIGCRKKYIDGEKQAEPVVVLDPVSTHEPQTKDQVAEKD :::::::::::::::::: CCDS73 GEGPRKLEGCTSSKVTFQ 550 >>CCDS58097.1 SHTN1 gene_id:57698|Hs108|chr10 (498 aa) initn: 3150 init1: 3150 opt: 3150 Z-score: 1501.1 bits: 287.6 E(32554): 2.7e-77 Smith-Waterman score: 3150; 100.0% identity (100.0% similar) in 498 aa overlap (61-558:1-498) 40 50 60 70 80 90 pF1KA1 NQKTKEKCDKIRQERDEAVKKLEEFQKISHMVIEEVNFMQNHLEIEKTCRESAEALATKL :::::::::::::::::::::::::::::: CCDS58 MVIEEVNFMQNHLEIEKTCRESAEALATKL 10 20 30 100 110 120 130 140 150 pF1KA1 NKENKTLKRISMLYMAKLGPDVITEEINIDDEDSTTDTDGAAETCVSVQCQKQIKELRDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 NKENKTLKRISMLYMAKLGPDVITEEINIDDEDSTTDTDGAAETCVSVQCQKQIKELRDQ 40 50 60 70 80 90 160 170 180 190 200 210 pF1KA1 IVSVQEEKKILAIELENLKSKLVEVIEEVNKVKQEKTVLNSEVLEQRKVLEKCNRVSMLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 IVSVQEEKKILAIELENLKSKLVEVIEEVNKVKQEKTVLNSEVLEQRKVLEKCNRVSMLA 100 110 120 130 140 150 220 230 240 250 260 270 pF1KA1 VEEYEEMQVNLELEKDLRKKAESFAQEMFIEQNKLKRQSHLLLQSSIPDQQLLKALDENA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VEEYEEMQVNLELEKDLRKKAESFAQEMFIEQNKLKRQSHLLLQSSIPDQQLLKALDENA 160 170 180 190 200 210 280 290 300 310 320 330 pF1KA1 KLTQQLEEERIQHQQKVKELEEQLENETLHKEIHNLKQQLELLEEDKKELELKYQNSEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 KLTQQLEEERIQHQQKVKELEEQLENETLHKEIHNLKQQLELLEEDKKELELKYQNSEEK 220 230 240 250 260 270 340 350 360 370 380 390 pF1KA1 ARNLKHSVDELQKRVNQSENSVPPPPPPPPPLPPPPPNPIRSLMSMIRKRSHPSGSGAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ARNLKHSVDELQKRVNQSENSVPPPPPPPPPLPPPPPNPIRSLMSMIRKRSHPSGSGAKK 280 290 300 310 320 330 400 410 420 430 440 450 pF1KA1 EKATQPETTEEVTDLKRQAVEEMMDRIKKGVHLRPVNQTARPKTKPESSKGCESAVDELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 EKATQPETTEEVTDLKRQAVEEMMDRIKKGVHLRPVNQTARPKTKPESSKGCESAVDELK 340 350 360 370 380 390 460 470 480 490 500 510 pF1KA1 GILGTLNKSTSSRSLKSLDPENSETELERILRRRKVTAEADSSSPTGILATSESKSMPVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GILGTLNKSTSSRSLKSLDPENSETELERILRRRKVTAEADSSSPTGILATSESKSMPVL 400 410 420 430 440 450 520 530 540 550 560 570 pF1KA1 GSVSSVTKTALNKKTLEAEFNSPSPPTPEPGEGPRKLEGCTSSKVTFQPPSSIGCRKKYI :::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GSVSSVTKTALNKKTLEAEFNSPSPPTPEPGEGPRKLEGCTSSKVTFQ 460 470 480 490 580 590 600 610 620 630 pF1KA1 DGEKQAEPVVVLDPVSTHEPQTKDQVAEKDPTQHKEDEGEIQPENKEDSIENVRETDSSN >>CCDS31293.1 SHTN1 gene_id:57698|Hs108|chr10 (456 aa) initn: 3100 init1: 2878 opt: 2878 Z-score: 1374.1 bits: 264.0 E(32554): 3.2e-70 Smith-Waterman score: 2878; 99.6% identity (100.0% similar) in 455 aa overlap (1-455:1-455) 10 20 30 40 50 60 pF1KA1 MNSSDEEKQLQLITSLKEQAIGEYEDLRAENQKTKEKCDKIRQERDEAVKKLEEFQKISH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MNSSDEEKQLQLITSLKEQAIGEYEDLRAENQKTKEKCDKIRQERDEAVKKLEEFQKISH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 MVIEEVNFMQNHLEIEKTCRESAEALATKLNKENKTLKRISMLYMAKLGPDVITEEINID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MVIEEVNFMQNHLEIEKTCRESAEALATKLNKENKTLKRISMLYMAKLGPDVITEEINID 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 DEDSTTDTDGAAETCVSVQCQKQIKELRDQIVSVQEEKKILAIELENLKSKLVEVIEEVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 DEDSTTDTDGAAETCVSVQCQKQIKELRDQIVSVQEEKKILAIELENLKSKLVEVIEEVN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 KVKQEKTVLNSEVLEQRKVLEKCNRVSMLAVEEYEEMQVNLELEKDLRKKAESFAQEMFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 KVKQEKTVLNSEVLEQRKVLEKCNRVSMLAVEEYEEMQVNLELEKDLRKKAESFAQEMFI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 EQNKLKRQSHLLLQSSIPDQQLLKALDENAKLTQQLEEERIQHQQKVKELEEQLENETLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 EQNKLKRQSHLLLQSSIPDQQLLKALDENAKLTQQLEEERIQHQQKVKELEEQLENETLH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 KEIHNLKQQLELLEEDKKELELKYQNSEEKARNLKHSVDELQKRVNQSENSVPPPPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 KEIHNLKQQLELLEEDKKELELKYQNSEEKARNLKHSVDELQKRVNQSENSVPPPPPPPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 PLPPPPPNPIRSLMSMIRKRSHPSGSGAKKEKATQPETTEEVTDLKRQAVEEMMDRIKKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 PLPPPPPNPIRSLMSMIRKRSHPSGSGAKKEKATQPETTEEVTDLKRQAVEEMMDRIKKG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 VHLRPVNQTARPKTKPESSKGCESAVDELKGILGTLNKSTSSRSLKSLDPENSETELERI :::::::::::::::::::::::::::::::::.. CCDS31 VHLRPVNQTARPKTKPESSKGCESAVDELKGILASQ 430 440 450 490 500 510 520 530 540 pF1KA1 LRRRKVTAEADSSSPTGILATSESKSMPVLGSVSSVTKTALNKKTLEAEFNSPSPPTPEP 631 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 21:31:35 2016 done: Wed Nov 2 21:31:36 2016 Total Scan time: 3.070 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]