FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1633, 1814 aa 1>>>pF1KA1633 1814 - 1814 aa - 1814 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.3825+/-0.00153; mu= -3.6419+/- 0.090 mean_var=374.1838+/-78.909, 0's: 0 Z-trim(107.7): 126 B-trim: 99 in 1/52 Lambda= 0.066303 statistics sampled from 9632 (9731) to 9632 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.628), E-opt: 0.2 (0.299), width: 16 Scan time: 6.770 The best scores are: opt bits E(32554) CCDS43871.1 CDK5RAP2 gene_id:55755|Hs108|chr9 (1814) 11608 1126.8 0 CCDS6823.1 CDK5RAP2 gene_id:55755|Hs108|chr9 (1893) 10032 976.0 0 CCDS75888.1 CDK5RAP2 gene_id:55755|Hs108|chr9 (1663) 4140 412.4 7.1e-114 >>CCDS43871.1 CDK5RAP2 gene_id:55755|Hs108|chr9 (1814 aa) initn: 11608 init1: 11608 opt: 11608 Z-score: 6018.0 bits: 1126.8 E(32554): 0 Smith-Waterman score: 11608; 99.9% identity (100.0% similar) in 1814 aa overlap (1-1814:1-1814) 10 20 30 40 50 60 pF1KA1 MMDLVLEEDVTVPGTLSGCSGLVPSVPDDLDGINPNAGLGNGLLPNVSEETVSPTRARNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MMDLVLEEDVTVPGTLSGCSGLVPSVPDDLDGINPNAGLGNGLLPNVSEETVSPTRARNM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KDFENQITELKKENFNLKLRIYFLEERMQQEFHGPTEHIYKTNIELKVEVESLKRELQER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 KDFENQITELKKENFNLKLRIYFLEERMQQEFHGPTEHIYKTNIELKVEVESLKRELQER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 EQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 EQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 AFAGTETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 AFAGTETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFQERIQALEEDLR ::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::: CCDS43 KEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEERIQALEEDLR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 EKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKAREALQKAQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 EKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKAREALQKAQT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 QEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKKITQELSDLQQERERLEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 QEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKKITQELSDLQQERERLEK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 DLEEAHREKSKGDCTIRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHNQEQVIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DLEEAHREKSKGDCTIRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHNQEQVIK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 HLTESTNQKDVLLQKFNEKDLEVIQQNCYLMAAEDLELRSEGLITEKCSSQQPPGSKTIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 HLTESTNQKDVLLQKFNEKDLEVIQQNCYLMAAEDLELRSEGLITEKCSSQQPPGSKTIF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SKEKKQSSDYEELIQVLKKEQDIYTHLVKSLQESDSINNLQAELNKIFALRKQLEQDVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SKEKKQSSDYEELIQVLKKEQDIYTHLVKSLQESDSINNLQAELNKIFALRKQLEQDVLS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 YQNLRKTLEEQISEIRRREEESFSLYSDQTSYLSICLEENNRFQVEHFSQEELKKKVSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 YQNLRKTLEEQISEIRRREEESFSLYSDQTSYLSICLEENNRFQVEHFSQEELKKKVSDL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 IQLVKELYTDNQHLKKTIFDLSCMGFQGNGFPDRLASTEQTELLASKEDEDTIKIGEDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 IQLVKELYTDNQHLKKTIFDLSCMGFQGNGFPDRLASTEQTELLASKEDEDTIKIGEDDE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 INFLSDQHLQQSNEIMKDLSKGGCKNGYLRHTESKISDCDGAHAPGCLEEGAFINLLAPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 INFLSDQHLQQSNEIMKDLSKGGCKNGYLRHTESKISDCDGAHAPGCLEEGAFINLLAPL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 FNEKATLLLESRPDLLKVVRELLLGQLFLTEQEVSGEHLDGKTEKTPKQKGELVHFVQTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 FNEKATLLLESRPDLLKVVRELLLGQLFLTEQEVSGEHLDGKTEKTPKQKGELVHFVQTN 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 SFSKPHDELKLSCEAQLVKAGEVPKVGLKDASVQTVATEGDLLRFKHEATREAWEEKPIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SFSKPHDELKLSCEAQLVKAGEVPKVGLKDASVQTVATEGDLLRFKHEATREAWEEKPIN 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 TALSAEHRPENLHGVPGWQAALLSLPGITNREAKKSRLPILIKPSRSLGNMYRLPATQEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 TALSAEHRPENLHGVPGWQAALLSLPGITNREAKKSRLPILIKPSRSLGNMYRLPATQEV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 VTQLQSQILELQGELKEFKTCNKQLHQKLILAEAVMEGRPTPDKTLLNAQPPVGAAYQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 VTQLQSQILELQGELKEFKTCNKQLHQKLILAEAVMEGRPTPDKTLLNAQPPVGAAYQDS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 PGEQKGIKTTSSVWRDKEMDSDQQRSYEIDSEICPPDDLASLPSCKENPEDVLSPTSVAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 PGEQKGIKTTSSVWRDKEMDSDQQRSYEIDSEICPPDDLASLPSCKENPEDVLSPTSVAT 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 YLSSKSQPSAKVSVMGTDQSESINTSNETEYLKQKIHDLETELEGYQNFIFQLQKHSQCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 YLSSKSQPSAKVSVMGTDQSESINTSNETEYLKQKIHDLETELEGYQNFIFQLQKHSQCS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 EAIITVLCGTEGAQDGLSKPKNGSDGEEMTFSSLHQVRYVKHVKILGPLAPEMIDSRVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 EAIITVLCGTEGAQDGLSKPKNGSDGEEMTFSSLHQVRYVKHVKILGPLAPEMIDSRVLE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 NLKQQLEEQEYKLQKEQNLNMQLFSEIHNLQNKFRDLSPPRYDSLVQSQARELSLQRQQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 NLKQQLEEQEYKLQKEQNLNMQLFSEIHNLQNKFRDLSPPRYDSLVQSQARELSLQRQQI 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 KDGHGICVISRQHMNTMIKAFEELLQASDVDYCVAEGFQEQLNQCAELLEKLEKLFLNGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 KDGHGICVISRQHMNTMIKAFEELLQASDVDYCVAEGFQEQLNQCAELLEKLEKLFLNGK 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA1 SVGVEMNTQNELMERIEEDNLTYQHLLPESPEPSASHALSDYETSEKSFFSRDQKQDNET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SVGVEMNTQNELMERIEEDNLTYQHLLPESPEPSASHALSDYETSEKSFFSRDQKQDNET 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA1 EKTSVMVNSFSQDLLMEHIQEIRTLRKRLEESIKTNEKLRKQLERQGSEFVQGSTSIFAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 EKTSVMVNSFSQDLLMEHIQEIRTLRKRLEESIKTNEKLRKQLERQGSEFVQGSTSIFAS 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA1 GSELHSSLTSEIHFLRKQNQALNAMLIKGSRDKQKENDKLRESLSRKTVSLEHLQREYAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 GSELHSSLTSEIHFLRKQNQALNAMLIKGSRDKQKENDKLRESLSRKTVSLEHLQREYAS 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA1 VKEENERLQKEGSEKERHNQQLIQEVRCSGQELSRVQEELKLRQQLLSQNDKLLQSLRVE :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: CCDS43 VKEENERLQKEGSEKERHNQQLIQEVRCSGQELSRVQEEVKLRQQLLSQNDKLLQSLRVE 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA1 LKAYEKLDEEHRRLRDGDKYPMESDNSFDLFDSSQAVTPKSVSETPPLSGNDTDSLSCDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LKAYEKLDEEHRRLRDGDKYPMESDNSFDLFDSSQAVTPKSVSETPPLSGNDTDSLSCDS 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA1 GSSATSTPCVSRLVTGHHLWASKNGRHVLGLIEDYEALLKQISQGQRLLAEMDIQTQEAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 GSSATSTPCVSRLVTGHHLWASKNGRHVLGLIEDYEALLKQISQGQRLLAEMDIQTQEAP 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA1 SSTSQELGTKGPHPAPLSKFVSSVSTAKLTLEEAYRRLKLLWRVSLPEDGQCPLHCEQIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SSTSQELGTKGPHPAPLSKFVSSVSTAKLTLEEAYRRLKLLWRVSLPEDGQCPLHCEQIG 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA1 EMKAEVTKLHKKLFEQEKKLQNTMKLLQLSKRQEKVIFDQLVVTHKILRKARGNLELRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 EMKAEVTKLHKKLFEQEKKLQNTMKLLQLSKRQEKVIFDQLVVTHKILRKARGNLELRPG 1750 1760 1770 1780 1790 1800 1810 pF1KA1 GAHPGTCSPSRPGS :::::::::::::: CCDS43 GAHPGTCSPSRPGS 1810 >>CCDS6823.1 CDK5RAP2 gene_id:55755|Hs108|chr9 (1893 aa) initn: 10031 init1: 10031 opt: 10032 Z-score: 5203.0 bits: 976.0 E(32554): 0 Smith-Waterman score: 11122; 95.6% identity (95.7% similar) in 1846 aa overlap (1-1767:1-1846) 10 20 30 40 50 60 pF1KA1 MMDLVLEEDVTVPGTLSGCSGLVPSVPDDLDGINPNAGLGNGLLPNVSEETVSPTRARNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 MMDLVLEEDVTVPGTLSGCSGLVPSVPDDLDGINPNAGLGNGLLPNVSEETVSPTRARNM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KDFENQITELKKENFNLKLRIYFLEERMQQEFHGPTEHIYKTNIELKVEVESLKRELQER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 KDFENQITELKKENFNLKLRIYFLEERMQQEFHGPTEHIYKTNIELKVEVESLKRELQER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 EQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 EQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 AFAGTETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 AFAGTETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFQERIQALEEDLR ::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::: CCDS68 KEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEERIQALEEDLR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 EKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKAREALQKAQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 EKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKAREALQKAQT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 QEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKKITQELSDLQQERERLEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 QEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKKITQELSDLQQERERLEK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 DLEEAHREKSKGDCTIRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHNQEQVIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 DLEEAHREKSKGDCTIRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHNQEQVIK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 HLTESTNQKDVLLQKFNEKDLEVIQQNCYLMAAEDLELRSEGLITEKCSSQQPPGSKTIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 HLTESTNQKDVLLQKFNEKDLEVIQQNCYLMAAEDLELRSEGLITEKCSSQQPPGSKTIF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SKEKKQSSDYEELIQVLKKEQDIYTHLVKSLQESDSINNLQAELNKIFALRKQLEQDVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 SKEKKQSSDYEELIQVLKKEQDIYTHLVKSLQESDSINNLQAELNKIFALRKQLEQDVLS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 YQNLRKTLEEQISEIRRREEESFSLYSDQTSYLSICLEENNRFQVEHFSQEELKKKVSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 YQNLRKTLEEQISEIRRREEESFSLYSDQTSYLSICLEENNRFQVEHFSQEELKKKVSDL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 IQLVKELYTDNQHLKKTIFDLSCMGFQGNGFPDRLASTEQTELLASKEDEDTIKIGEDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 IQLVKELYTDNQHLKKTIFDLSCMGFQGNGFPDRLASTEQTELLASKEDEDTIKIGEDDE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 INFLSDQHLQQSNEIMKDLSKGGCKNGYLRHTESKISDCDGAHAPGCLEEGAFINLLAPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 INFLSDQHLQQSNEIMKDLSKGGCKNGYLRHTESKISDCDGAHAPGCLEEGAFINLLAPL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 FNEKATLLLESRPDLLKVVRELLLGQLFLTEQEVSGEHLDGKTEKTPKQKGELVHFVQTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 FNEKATLLLESRPDLLKVVRELLLGQLFLTEQEVSGEHLDGKTEKTPKQKGELVHFVQTN 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 SFSKPHDELKLSCEAQLVKAGEVPKVGLKDASVQTVATEGDLLRFKHEATREAWEEKPIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 SFSKPHDELKLSCEAQLVKAGEVPKVGLKDASVQTVATEGDLLRFKHEATREAWEEKPIN 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 TALSAEHRPENLHGVPGWQAALLSLPGITNREAKKSRLPILIKPSRSLGNMYRLPATQEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 TALSAEHRPENLHGVPGWQAALLSLPGITNREAKKSRLPILIKPSRSLGNMYRLPATQEV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 VTQLQSQILELQGELKEFKTCNKQLHQKLILAEAVMEGRPTPDKTLLNAQPPVGAAYQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 VTQLQSQILELQGELKEFKTCNKQLHQKLILAEAVMEGRPTPDKTLLNAQPPVGAAYQDS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 PGEQKGIKTTSSVWRDKEMDSDQQRSYEIDSEICPPDDLASLPSCKENPEDVLSPTSVAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 PGEQKGIKTTSSVWRDKEMDSDQQRSYEIDSEICPPDDLASLPSCKENPEDVLSPTSVAT 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 YLSSKSQPSAKVSVMGTDQSESINTSNETEYLKQKIHDLETELEGYQNFIFQLQKHSQCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 YLSSKSQPSAKVSVMGTDQSESINTSNETEYLKQKIHDLETELEGYQNFIFQLQKHSQCS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 EAIITVLCGTEGAQDGLSKPKNGSDGEEMTFSSLHQVRYVKHVKILGPLAPEMIDSRVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 EAIITVLCGTEGAQDGLSKPKNGSDGEEMTFSSLHQVRYVKHVKILGPLAPEMIDSRVLE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 NLKQQLEEQEYKLQKEQNLNMQLFSEIHNLQNKFRDLSPPRYDSLVQSQARELSLQRQQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 NLKQQLEEQEYKLQKEQNLNMQLFSEIHNLQNKFRDLSPPRYDSLVQSQARELSLQRQQI 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 KDGHGICVISRQHMNTMIKAFEELLQASDVDYCVAEGFQEQLNQCAELLEKLEKLFLNGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 KDGHGICVISRQHMNTMIKAFEELLQASDVDYCVAEGFQEQLNQCAELLEKLEKLFLNGK 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA1 SVGVEMNTQNELMERIEEDNLTYQHLLPESPEPSASHALSDYETSEKSFFSRDQKQDNET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 SVGVEMNTQNELMERIEEDNLTYQHLLPESPEPSASHALSDYETSEKSFFSRDQKQDNET 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA1 EKTSVMVNSFSQDLLMEHIQEIRTLRKRLEESIKTNEKLRKQLERQGSEFVQGSTSIFAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 EKTSVMVNSFSQDLLMEHIQEIRTLRKRLEESIKTNEKLRKQLERQGSEFVQGSTSIFAS 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA1 GSELHSSLTSEIHFLRKQNQALNAMLIKGSRDKQKENDKLRESLSRKTVSLEHLQREYAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 GSELHSSLTSEIHFLRKQNQALNAMLIKGSRDKQKENDKLRESLSRKTVSLEHLQREYAS 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA1 VKEENERLQKEGSEKERHNQQLIQEVRCSGQELSRVQEELKLRQQLLSQNDKLLQSLRVE :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: CCDS68 VKEENERLQKEGSEKERHNQQLIQEVRCSGQELSRVQEEVKLRQQLLSQNDKLLQSLRVE 1510 1520 1530 1540 1550 1560 1570 pF1KA1 LKAYEKLDEEHRRLR--------------------------------------------- ::::::::::::::: CCDS68 LKAYEKLDEEHRRLREASGEGWKGQDPFRDLHSLLMEIQALRLQLERSIETSSTLQSRLK 1570 1580 1590 1600 1610 1620 1580 1590 1600 pF1KA1 ----------------------------------DGDKYPMESDNSFDLFDSSQAVTPKS :::::::::::::::::::::::::: CCDS68 EQLARGAEKAQEGALTLAVQAVSIPEVPLQPDKHDGDKYPMESDNSFDLFDSSQAVTPKS 1630 1640 1650 1660 1670 1680 1610 1620 1630 1640 1650 1660 pF1KA1 VSETPPLSGNDTDSLSCDSGSSATSTPCVSRLVTGHHLWASKNGRHVLGLIEDYEALLKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 VSETPPLSGNDTDSLSCDSGSSATSTPCVSRLVTGHHLWASKNGRHVLGLIEDYEALLKQ 1690 1700 1710 1720 1730 1740 1670 1680 1690 1700 1710 1720 pF1KA1 ISQGQRLLAEMDIQTQEAPSSTSQELGTKGPHPAPLSKFVSSVSTAKLTLEEAYRRLKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 ISQGQRLLAEMDIQTQEAPSSTSQELGTKGPHPAPLSKFVSSVSTAKLTLEEAYRRLKLL 1750 1760 1770 1780 1790 1800 1730 1740 1750 1760 1770 1780 pF1KA1 WRVSLPEDGQCPLHCEQIGEMKAEVTKLHKKLFEQEKKLQNTMKLLQLSKRQEKVIFDQL :::::::::::::::::::::::::::::::::::::::::::::: CCDS68 WRVSLPEDGQCPLHCEQIGEMKAEVTKLHKKLFEQEKKLQNTMKLLQLSKRQEKVIFDQL 1810 1820 1830 1840 1850 1860 1790 1800 1810 pF1KA1 VVTHKILRKARGNLELRPGGAHPGTCSPSRPGS CCDS68 VVTHKILRKARGNLELRPGGAHPGTCSPSRPGS 1870 1880 1890 >>CCDS75888.1 CDK5RAP2 gene_id:55755|Hs108|chr9 (1663 aa) initn: 7977 init1: 4139 opt: 4140 Z-score: 2157.9 bits: 412.4 E(32554): 7.1e-114 Smith-Waterman score: 9131; 83.2% identity (83.3% similar) in 1846 aa overlap (1-1767:1-1616) 10 20 30 40 50 60 pF1KA1 MMDLVLEEDVTVPGTLSGCSGLVPSVPDDLDGINPNAGLGNGLLPNVSEETVSPTRARNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 MMDLVLEEDVTVPGTLSGCSGLVPSVPDDLDGINPNAGLGNGLLPNVSEETVSPTRARNM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KDFENQITELKKENFNLKLRIYFLEERMQQEFHGPTEHIYKTNIELKVEVESLKRELQER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 KDFENQITELKKENFNLKLRIYFLEERMQQEFHGPTEHIYKTNIELKVEVESLKRELQER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 EQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 EQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 AFAGTETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 AFAGTETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFQERIQALEEDLR ::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::: CCDS75 KEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEERIQALEEDLR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 EKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKAREALQKAQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 EKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKAREALQKAQT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 QEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKKITQELSDLQQERERLEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 QEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKKITQELSDLQQERERLEK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 DLEEAHREKSKGDCTIRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHNQEQVIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 DLEEAHREKSKGDCTIRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHNQEQVIK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 HLTESTNQKDVLLQKFNEKDLEVIQQNCYLMAAEDLELRSEGLITEKCSSQQPPGSKTIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 HLTESTNQKDVLLQKFNEKDLEVIQQNCYLMAAEDLELRSEGLITEKCSSQQPPGSKTIF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SKEKKQSSDYEELIQVLKKEQDIYTHLVKSLQESDSINNLQAELNKIFALRKQLEQDVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 SKEKKQSSDYEELIQVLKKEQDIYTHLVKSLQESDSINNLQAELNKIFALRKQLEQDVLS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 YQNLRKTLEEQISEIRRREEESFSLYSDQTSYLSICLEENNRFQVEHFSQEELKKKVSDL :::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::: CCDS75 YQNLRKTLEEQISEIRRREE-SFSLYSDQTSYLSICLEENNRFQVEHFSQEELKKKVSDL 610 620 630 640 650 670 680 690 700 710 720 pF1KA1 IQLVKELYTDNQHLKKTIFDLSCMGFQGNGFPDRLASTEQTELLASKEDEDTIKIGEDDE :::::::::::::::::::::::::::::::::::::::::: CCDS75 IQLVKELYTDNQHLKKTIFDLSCMGFQGNGFPDRLASTEQTE------------------ 660 670 680 690 700 730 740 750 760 770 780 pF1KA1 INFLSDQHLQQSNEIMKDLSKGGCKNGYLRHTESKISDCDGAHAPGCLEEGAFINLLAPL CCDS75 ------------------------------------------------------------ 790 800 810 820 830 840 pF1KA1 FNEKATLLLESRPDLLKVVRELLLGQLFLTEQEVSGEHLDGKTEKTPKQKGELVHFVQTN CCDS75 ------------------------------------------------------------ 850 860 870 880 890 900 pF1KA1 SFSKPHDELKLSCEAQLVKAGEVPKVGLKDASVQTVATEGDLLRFKHEATREAWEEKPIN CCDS75 ------------------------------------------------------------ 910 920 930 940 950 960 pF1KA1 TALSAEHRPENLHGVPGWQAALLSLPGITNREAKKSRLPILIKPSRSLGNMYRLPATQEV ::::::::::::::::::::::::::::: CCDS75 -------------------------------EAKKSRLPILIKPSRSLGNMYRLPATQEV 710 720 730 970 980 990 1000 1010 1020 pF1KA1 VTQLQSQILELQGELKEFKTCNKQLHQKLILAEAVMEGRPTPDKTLLNAQPPVGAAYQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 VTQLQSQILELQGELKEFKTCNKQLHQKLILAEAVMEGRPTPDKTLLNAQPPVGAAYQDS 740 750 760 770 780 790 1030 1040 1050 1060 1070 1080 pF1KA1 PGEQKGIKTTSSVWRDKEMDSDQQRSYEIDSEICPPDDLASLPSCKENPEDVLSPTSVAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 PGEQKGIKTTSSVWRDKEMDSDQQRSYEIDSEICPPDDLASLPSCKENPEDVLSPTSVAT 800 810 820 830 840 850 1090 1100 1110 1120 1130 1140 pF1KA1 YLSSKSQPSAKVSVMGTDQSESINTSNETEYLKQKIHDLETELEGYQNFIFQLQKHSQCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 YLSSKSQPSAKVSVMGTDQSESINTSNETEYLKQKIHDLETELEGYQNFIFQLQKHSQCS 860 870 880 890 900 910 1150 1160 1170 1180 1190 1200 pF1KA1 EAIITVLCGTEGAQDGLSKPKNGSDGEEMTFSSLHQVRYVKHVKILGPLAPEMIDSRVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 EAIITVLCGTEGAQDGLSKPKNGSDGEEMTFSSLHQVRYVKHVKILGPLAPEMIDSRVLE 920 930 940 950 960 970 1210 1220 1230 1240 1250 1260 pF1KA1 NLKQQLEEQEYKLQKEQNLNMQLFSEIHNLQNKFRDLSPPRYDSLVQSQARELSLQRQQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 NLKQQLEEQEYKLQKEQNLNMQLFSEIHNLQNKFRDLSPPRYDSLVQSQARELSLQRQQI 980 990 1000 1010 1020 1030 1270 1280 1290 1300 1310 1320 pF1KA1 KDGHGICVISRQHMNTMIKAFEELLQASDVDYCVAEGFQEQLNQCAELLEKLEKLFLNGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 KDGHGICVISRQHMNTMIKAFEELLQASDVDYCVAEGFQEQLNQCAELLEKLEKLFLNGK 1040 1050 1060 1070 1080 1090 1330 1340 1350 1360 1370 1380 pF1KA1 SVGVEMNTQNELMERIEEDNLTYQHLLPESPEPSASHALSDYETSEKSFFSRDQKQDNET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 SVGVEMNTQNELMERIEEDNLTYQHLLPESPEPSASHALSDYETSEKSFFSRDQKQDNET 1100 1110 1120 1130 1140 1150 1390 1400 1410 1420 1430 1440 pF1KA1 EKTSVMVNSFSQDLLMEHIQEIRTLRKRLEESIKTNEKLRKQLERQGSEFVQGSTSIFAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 EKTSVMVNSFSQDLLMEHIQEIRTLRKRLEESIKTNEKLRKQLERQGSEFVQGSTSIFAS 1160 1170 1180 1190 1200 1210 1450 1460 1470 1480 1490 1500 pF1KA1 GSELHSSLTSEIHFLRKQNQALNAMLIKGSRDKQKENDKLRESLSRKTVSLEHLQREYAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 GSELHSSLTSEIHFLRKQNQALNAMLIKGSRDKQKENDKLRESLSRKTVSLEHLQREYAS 1220 1230 1240 1250 1260 1270 1510 1520 1530 1540 1550 1560 pF1KA1 VKEENERLQKEGSEKERHNQQLIQEVRCSGQELSRVQEELKLRQQLLSQNDKLLQSLRVE :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: CCDS75 VKEENERLQKEGSEKERHNQQLIQEVRCSGQELSRVQEEVKLRQQLLSQNDKLLQSLRVE 1280 1290 1300 1310 1320 1330 1570 pF1KA1 LKAYEKLDEEHRRLR--------------------------------------------- ::::::::::::::: CCDS75 LKAYEKLDEEHRRLREASGEGWKGQDPFRDLHSLLMEIQALRLQLERSIETSSTLQSRLK 1340 1350 1360 1370 1380 1390 1580 1590 1600 pF1KA1 ----------------------------------DGDKYPMESDNSFDLFDSSQAVTPKS :::::::::::::::::::::::::: CCDS75 EQLARGAEKAQEGALTLAVQAVSIPEVPLQPDKHDGDKYPMESDNSFDLFDSSQAVTPKS 1400 1410 1420 1430 1440 1450 1610 1620 1630 1640 1650 1660 pF1KA1 VSETPPLSGNDTDSLSCDSGSSATSTPCVSRLVTGHHLWASKNGRHVLGLIEDYEALLKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 VSETPPLSGNDTDSLSCDSGSSATSTPCVSRLVTGHHLWASKNGRHVLGLIEDYEALLKQ 1460 1470 1480 1490 1500 1510 1670 1680 1690 1700 1710 1720 pF1KA1 ISQGQRLLAEMDIQTQEAPSSTSQELGTKGPHPAPLSKFVSSVSTAKLTLEEAYRRLKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 ISQGQRLLAEMDIQTQEAPSSTSQELGTKGPHPAPLSKFVSSVSTAKLTLEEAYRRLKLL 1520 1530 1540 1550 1560 1570 1730 1740 1750 1760 1770 1780 pF1KA1 WRVSLPEDGQCPLHCEQIGEMKAEVTKLHKKLFEQEKKLQNTMKLLQLSKRQEKVIFDQL :::::::::::::::::::::::::::::::::::::::::::::: CCDS75 WRVSLPEDGQCPLHCEQIGEMKAEVTKLHKKLFEQEKKLQNTMKLLQLSKRQEKVIFDQL 1580 1590 1600 1610 1620 1630 1790 1800 1810 pF1KA1 VVTHKILRKARGNLELRPGGAHPGTCSPSRPGS CCDS75 VVTHKILRKARGNLELRPGGAHPGTCSPSRPGS 1640 1650 1660 1814 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 02:22:47 2016 done: Sat Nov 5 02:22:48 2016 Total Scan time: 6.770 Total Display time: 0.330 Function used was FASTA [36.3.4 Apr, 2011]