Result of FASTA (omim) for
pF1KA1649
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1649, 421 aa
1>>>pF1KA1649 421 - 421 aa - 421 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6905+/-0.000358; mu= 11.6064+/- 0.022
mean_var=105.7342+/-21.126, 0's: 0 Z-trim(116.6): 34 B-trim: 269 in 1/56
Lambda= 0.124729
statistics sampled from 27826 (27859) to 27826 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.327), width: 16
Scan time: 8.690
The best scores are: opt bits E(85289)
NP_115687 (OMIM: 611520) polymerase delta-interact ( 421) 2719 499.8 5.3e-141
XP_011528759 (OMIM: 611520) PREDICTED: polymerase ( 342) 2203 406.9 4e-113
NP_001265586 (OMIM: 611520) polymerase delta-inter ( 438) 1872 347.4 4.2e-95
NP_835237 (OMIM: 611520) polymerase delta-interact ( 392) 1633 304.4 3.4e-82
XP_016884500 (OMIM: 611520) PREDICTED: polymerase ( 218) 1381 258.9 9.3e-69
XP_016884499 (OMIM: 611520) PREDICTED: polymerase ( 313) 1117 211.4 2.5e-54
>>NP_115687 (OMIM: 611520) polymerase delta-interacting (421 aa)
initn: 2719 init1: 2719 opt: 2719 Z-score: 2652.4 bits: 499.8 E(85289): 5.3e-141
Smith-Waterman score: 2719; 100.0% identity (100.0% similar) in 421 aa overlap (1-421:1-421)
10 20 30 40 50 60
pF1KA1 MADISLDELIRKRGAAAKGRLNARPGVGGVRSRVGIQQGLLSQSTRTATFQQRFDARQKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MADISLDELIRKRGAAAKGRLNARPGVGGVRSRVGIQQGLLSQSTRTATFQQRFDARQKI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 GLSDARLKLGVKDAREKLLQKDARFRIKGKVQDAREMLNSRKQQTTVPQKPRQVADAREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 GLSDARLKLGVKDAREKLLQKDARFRIKGKVQDAREMLNSRKQQTTVPQKPRQVADAREK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 ISLKRSSPAAFINPPIGTVTPALKLTKTIQVPQQKAMAPLHPHPAGMRINVVNNHQAKQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 ISLKRSSPAAFINPPIGTVTPALKLTKTIQVPQQKAMAPLHPHPAGMRINVVNNHQAKQN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LYDLDEDDDGIASVPTKQMKFAASGGFLHHMAGLSSSKLSMSKALPLTKVVQNDAYTAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LYDLDEDDDGIASVPTKQMKFAASGGFLHHMAGLSSSKLSMSKALPLTKVVQNDAYTAPA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 LPSSIRTKALTNMSRTLVNKEEPPKELPAAEPVLSPLEGTKMTVNNLHPRVTEEDIVELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LPSSIRTKALTNMSRTLVNKEEPPKELPAAEPVLSPLEGTKMTVNNLHPRVTEEDIVELF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 CVCGALKRARLVHPGVAEVVFVKKDDAITAYKKYNNRCLDGQPMKCNLHMNGNVITSDQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 CVCGALKRARLVHPGVAEVVFVKKDDAITAYKKYNNRCLDGQPMKCNLHMNGNVITSDQP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 ILLRLSDSPSMKKESELPRRVNSASSSNPPAEVDPDTILKALFKSSGASVTTQPTEFKIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 ILLRLSDSPSMKKESELPRRVNSASSSNPPAEVDPDTILKALFKSSGASVTTQPTEFKIK
370 380 390 400 410 420
pF1KA1 L
:
NP_115 L
>>XP_011528759 (OMIM: 611520) PREDICTED: polymerase delt (342 aa)
initn: 2203 init1: 2203 opt: 2203 Z-score: 2151.9 bits: 406.9 E(85289): 4e-113
Smith-Waterman score: 2203; 100.0% identity (100.0% similar) in 341 aa overlap (1-341:1-341)
10 20 30 40 50 60
pF1KA1 MADISLDELIRKRGAAAKGRLNARPGVGGVRSRVGIQQGLLSQSTRTATFQQRFDARQKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MADISLDELIRKRGAAAKGRLNARPGVGGVRSRVGIQQGLLSQSTRTATFQQRFDARQKI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 GLSDARLKLGVKDAREKLLQKDARFRIKGKVQDAREMLNSRKQQTTVPQKPRQVADAREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLSDARLKLGVKDAREKLLQKDARFRIKGKVQDAREMLNSRKQQTTVPQKPRQVADAREK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 ISLKRSSPAAFINPPIGTVTPALKLTKTIQVPQQKAMAPLHPHPAGMRINVVNNHQAKQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISLKRSSPAAFINPPIGTVTPALKLTKTIQVPQQKAMAPLHPHPAGMRINVVNNHQAKQN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LYDLDEDDDGIASVPTKQMKFAASGGFLHHMAGLSSSKLSMSKALPLTKVVQNDAYTAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYDLDEDDDGIASVPTKQMKFAASGGFLHHMAGLSSSKLSMSKALPLTKVVQNDAYTAPA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 LPSSIRTKALTNMSRTLVNKEEPPKELPAAEPVLSPLEGTKMTVNNLHPRVTEEDIVELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPSSIRTKALTNMSRTLVNKEEPPKELPAAEPVLSPLEGTKMTVNNLHPRVTEEDIVELF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 CVCGALKRARLVHPGVAEVVFVKKDDAITAYKKYNNRCLDGQPMKCNLHMNGNVITSDQP
:::::::::::::::::::::::::::::::::::::::::
XP_011 CVCGALKRARLVHPGVAEVVFVKKDDAITAYKKYNNRCLDGG
310 320 330 340
370 380 390 400 410 420
pF1KA1 ILLRLSDSPSMKKESELPRRVNSASSSNPPAEVDPDTILKALFKSSGASVTTQPTEFKIK
>>NP_001265586 (OMIM: 611520) polymerase delta-interacti (438 aa)
initn: 1786 init1: 1786 opt: 1872 Z-score: 1828.4 bits: 347.4 E(85289): 4.2e-95
Smith-Waterman score: 2675; 96.1% identity (96.1% similar) in 438 aa overlap (1-421:1-438)
10 20 30 40 50 60
pF1KA1 MADISLDELIRKRGAAAKGRLNARPGVGGVRSRVGIQQGLLSQSTRTATFQQRFDARQKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADISLDELIRKRGAAAKGRLNARPGVGGVRSRVGIQQGLLSQSTRTATFQQRFDARQKI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 GLSDARLKLGVKDAREKLLQKDARFRIKGKVQDAREMLNSRKQQTTVPQKPRQVADAREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLSDARLKLGVKDAREKLLQKDARFRIKGKVQDAREMLNSRKQQTTVPQKPRQVADAREK
70 80 90 100 110 120
130 140 150 160
pF1KA1 ISLKRSSPAAFINPPIGTVTPALKLTKTIQ-----------------VPQQKAMAPLHPH
:::::::::::::::::::::::::::::: :::::::::::::
NP_001 ISLKRSSPAAFINPPIGTVTPALKLTKTIQRMHVDPVGWILTTECFQVPQQKAMAPLHPH
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 PAGMRINVVNNHQAKQNLYDLDEDDDGIASVPTKQMKFAASGGFLHHMAGLSSSKLSMSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAGMRINVVNNHQAKQNLYDLDEDDDGIASVPTKQMKFAASGGFLHHMAGLSSSKLSMSK
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA1 ALPLTKVVQNDAYTAPALPSSIRTKALTNMSRTLVNKEEPPKELPAAEPVLSPLEGTKMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALPLTKVVQNDAYTAPALPSSIRTKALTNMSRTLVNKEEPPKELPAAEPVLSPLEGTKMT
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA1 VNNLHPRVTEEDIVELFCVCGALKRARLVHPGVAEVVFVKKDDAITAYKKYNNRCLDGQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNNLHPRVTEEDIVELFCVCGALKRARLVHPGVAEVVFVKKDDAITAYKKYNNRCLDGQP
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 MKCNLHMNGNVITSDQPILLRLSDSPSMKKESELPRRVNSASSSNPPAEVDPDTILKALF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKCNLHMNGNVITSDQPILLRLSDSPSMKKESELPRRVNSASSSNPPAEVDPDTILKALF
370 380 390 400 410 420
410 420
pF1KA1 KSSGASVTTQPTEFKIKL
::::::::::::::::::
NP_001 KSSGASVTTQPTEFKIKL
430
>>NP_835237 (OMIM: 611520) polymerase delta-interacting (392 aa)
initn: 1576 init1: 1576 opt: 1633 Z-score: 1596.7 bits: 304.4 E(85289): 3.4e-82
Smith-Waterman score: 2446; 93.1% identity (93.1% similar) in 421 aa overlap (1-421:1-392)
10 20 30 40 50 60
pF1KA1 MADISLDELIRKRGAAAKGRLNARPGVGGVRSRVGIQQGLLSQSTRTATFQQRFDARQKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 MADISLDELIRKRGAAAKGRLNARPGVGGVRSRVGIQQGLLSQSTRTATFQQRFDARQKI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 GLSDARLKLGVKDAREKLLQKDARFRIKGKVQDAREMLNSRKQQTTVPQKPRQVADAREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 GLSDARLKLGVKDAREKLLQKDARFRIKGKVQDAREMLNSRKQQTTVPQKPRQVADAREK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 ISLKRSSPAAFINPPIGTVTPALKLTKTIQVPQQKAMAPLHPHPAGMRINVVNNHQAKQN
:::::::::::::::::::::::::::::: :
NP_835 ISLKRSSPAAFINPPIGTVTPALKLTKTIQ-----------------------------N
130 140 150
190 200 210 220 230 240
pF1KA1 LYDLDEDDDGIASVPTKQMKFAASGGFLHHMAGLSSSKLSMSKALPLTKVVQNDAYTAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 LYDLDEDDDGIASVPTKQMKFAASGGFLHHMAGLSSSKLSMSKALPLTKVVQNDAYTAPA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KA1 LPSSIRTKALTNMSRTLVNKEEPPKELPAAEPVLSPLEGTKMTVNNLHPRVTEEDIVELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 LPSSIRTKALTNMSRTLVNKEEPPKELPAAEPVLSPLEGTKMTVNNLHPRVTEEDIVELF
220 230 240 250 260 270
310 320 330 340 350 360
pF1KA1 CVCGALKRARLVHPGVAEVVFVKKDDAITAYKKYNNRCLDGQPMKCNLHMNGNVITSDQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 CVCGALKRARLVHPGVAEVVFVKKDDAITAYKKYNNRCLDGQPMKCNLHMNGNVITSDQP
280 290 300 310 320 330
370 380 390 400 410 420
pF1KA1 ILLRLSDSPSMKKESELPRRVNSASSSNPPAEVDPDTILKALFKSSGASVTTQPTEFKIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 ILLRLSDSPSMKKESELPRRVNSASSSNPPAEVDPDTILKALFKSSGASVTTQPTEFKIK
340 350 360 370 380 390
pF1KA1 L
:
NP_835 L
>>XP_016884500 (OMIM: 611520) PREDICTED: polymerase delt (218 aa)
initn: 1370 init1: 1370 opt: 1381 Z-score: 1355.4 bits: 258.9 E(85289): 9.3e-69
Smith-Waterman score: 1381; 98.6% identity (99.5% similar) in 218 aa overlap (1-217:1-218)
10 20 30 40 50 60
pF1KA1 MADISLDELIRKRGAAAKGRLNARPGVGGVRSRVGIQQGLLSQSTRTATFQQRFDARQKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MADISLDELIRKRGAAAKGRLNARPGVGGVRSRVGIQQGLLSQSTRTATFQQRFDARQKI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 GLSDARLKLGVKDAREKLLQKDARFRIKGKVQDAREMLNSRKQQTTVPQKPRQVADAREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLSDARLKLGVKDAREKLLQKDARFRIKGKVQDAREMLNSRKQQTTVPQKPRQVADAREK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 ISLKRSSPAAFINPPIGTVTPALKLTKTIQVPQQKAMAPLHPHPAGMRINVVNNHQAKQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISLKRSSPAAFINPPIGTVTPALKLTKTIQVPQQKAMAPLHPHPAGMRINVVNNHQAKQN
130 140 150 160 170 180
190 200 210 220 230
pF1KA1 LYDLDEDDDGIASVPTKQMKFAASGGFLHHMA-GLSSSKLSMSKALPLTKVVQNDAYTAP
:::::::::::::::::::::::::::::::. ::::.
XP_016 LYDLDEDDDGIASVPTKQMKFAASGGFLHHMGPGLSSN
190 200 210
240 250 260 270 280 290
pF1KA1 ALPSSIRTKALTNMSRTLVNKEEPPKELPAAEPVLSPLEGTKMTVNNLHPRVTEEDIVEL
>>XP_016884499 (OMIM: 611520) PREDICTED: polymerase delt (313 aa)
initn: 1060 init1: 1060 opt: 1117 Z-score: 1096.3 bits: 211.4 E(85289): 2.5e-54
Smith-Waterman score: 1930; 91.5% identity (91.5% similar) in 341 aa overlap (1-341:1-312)
10 20 30 40 50 60
pF1KA1 MADISLDELIRKRGAAAKGRLNARPGVGGVRSRVGIQQGLLSQSTRTATFQQRFDARQKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MADISLDELIRKRGAAAKGRLNARPGVGGVRSRVGIQQGLLSQSTRTATFQQRFDARQKI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 GLSDARLKLGVKDAREKLLQKDARFRIKGKVQDAREMLNSRKQQTTVPQKPRQVADAREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLSDARLKLGVKDAREKLLQKDARFRIKGKVQDAREMLNSRKQQTTVPQKPRQVADAREK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 ISLKRSSPAAFINPPIGTVTPALKLTKTIQVPQQKAMAPLHPHPAGMRINVVNNHQAKQN
:::::::::::::::::::::::::::::: :
XP_016 ISLKRSSPAAFINPPIGTVTPALKLTKTIQ-----------------------------N
130 140 150
190 200 210 220 230 240
pF1KA1 LYDLDEDDDGIASVPTKQMKFAASGGFLHHMAGLSSSKLSMSKALPLTKVVQNDAYTAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYDLDEDDDGIASVPTKQMKFAASGGFLHHMAGLSSSKLSMSKALPLTKVVQNDAYTAPA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KA1 LPSSIRTKALTNMSRTLVNKEEPPKELPAAEPVLSPLEGTKMTVNNLHPRVTEEDIVELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPSSIRTKALTNMSRTLVNKEEPPKELPAAEPVLSPLEGTKMTVNNLHPRVTEEDIVELF
220 230 240 250 260 270
310 320 330 340 350 360
pF1KA1 CVCGALKRARLVHPGVAEVVFVKKDDAITAYKKYNNRCLDGQPMKCNLHMNGNVITSDQP
:::::::::::::::::::::::::::::::::::::::::
XP_016 CVCGALKRARLVHPGVAEVVFVKKDDAITAYKKYNNRCLDGG
280 290 300 310
370 380 390 400 410 420
pF1KA1 ILLRLSDSPSMKKESELPRRVNSASSSNPPAEVDPDTILKALFKSSGASVTTQPTEFKIK
421 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 21:37:24 2016 done: Wed Nov 2 21:37:26 2016
Total Scan time: 8.690 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]