Result of FASTA (omim) for
pF1KA1667
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1667, 708 aa
1>>>pF1KA1667 708 - 708 aa - 708 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.6132+/-0.000393; mu= 4.2788+/- 0.024
mean_var=168.0788+/-34.439, 0's: 0 Z-trim(117.6): 46 B-trim: 504 in 1/55
Lambda= 0.098928
statistics sampled from 29781 (29827) to 29781 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.701), E-opt: 0.2 (0.35), width: 16
Scan time: 10.020
The best scores are: opt bits E(85289)
XP_016884531 (OMIM: 606682,614073) PREDICTED: Herm ( 708) 4727 687.3 5.6e-197
NP_071364 (OMIM: 606682,614073) Hermansky-Pudlak s ( 708) 4727 687.3 5.6e-197
XP_016884533 (OMIM: 606682,614073) PREDICTED: Herm ( 708) 4727 687.3 5.6e-197
XP_016884532 (OMIM: 606682,614073) PREDICTED: Herm ( 708) 4727 687.3 5.6e-197
NP_690054 (OMIM: 606682,614073) Hermansky-Pudlak s ( 703) 4644 675.4 2e-193
XP_016884535 (OMIM: 606682,614073) PREDICTED: Herm ( 680) 4358 634.6 3.8e-181
XP_016884538 (OMIM: 606682,614073) PREDICTED: Herm ( 655) 4346 632.9 1.2e-180
XP_016884537 (OMIM: 606682,614073) PREDICTED: Herm ( 655) 4346 632.9 1.2e-180
XP_016884540 (OMIM: 606682,614073) PREDICTED: Herm ( 649) 3856 562.9 1.4e-159
XP_016884539 (OMIM: 606682,614073) PREDICTED: Herm ( 649) 3856 562.9 1.4e-159
XP_016884543 (OMIM: 606682,614073) PREDICTED: Herm ( 554) 3585 524.2 5.3e-148
XP_011528792 (OMIM: 606682,614073) PREDICTED: Herm ( 734) 3587 524.6 5.5e-148
XP_016884534 (OMIM: 606682,614073) PREDICTED: Herm ( 681) 3206 470.2 1.2e-131
XP_011528796 (OMIM: 606682,614073) PREDICTED: Herm ( 488) 3145 461.4 3.8e-129
XP_011528798 (OMIM: 606682,614073) PREDICTED: Herm ( 488) 3145 461.4 3.8e-129
XP_016884544 (OMIM: 606682,614073) PREDICTED: Herm ( 488) 3145 461.4 3.8e-129
XP_011528797 (OMIM: 606682,614073) PREDICTED: Herm ( 537) 3145 461.4 4.1e-129
XP_006724423 (OMIM: 606682,614073) PREDICTED: Herm ( 537) 3145 461.4 4.1e-129
XP_016884542 (OMIM: 606682,614073) PREDICTED: Herm ( 567) 3145 461.4 4.3e-129
XP_016884541 (OMIM: 606682,614073) PREDICTED: Herm ( 572) 3145 461.4 4.3e-129
XP_006724417 (OMIM: 606682,614073) PREDICTED: Herm ( 726) 3145 461.5 5.3e-129
XP_006724416 (OMIM: 606682,614073) PREDICTED: Herm ( 726) 3145 461.5 5.3e-129
XP_011528787 (OMIM: 606682,614073) PREDICTED: Herm ( 752) 3145 461.5 5.5e-129
XP_011528789 (OMIM: 606682,614073) PREDICTED: Herm ( 752) 3145 461.5 5.5e-129
XP_011528791 (OMIM: 606682,614073) PREDICTED: Herm ( 752) 3145 461.5 5.5e-129
XP_011528788 (OMIM: 606682,614073) PREDICTED: Herm ( 752) 3145 461.5 5.5e-129
XP_011528790 (OMIM: 606682,614073) PREDICTED: Herm ( 752) 3145 461.5 5.5e-129
XP_016884549 (OMIM: 606682,614073) PREDICTED: Herm ( 443) 2949 433.4 9.2e-121
XP_016884552 (OMIM: 606682,614073) PREDICTED: Herm ( 443) 2949 433.4 9.2e-121
XP_016884545 (OMIM: 606682,614073) PREDICTED: Herm ( 443) 2949 433.4 9.2e-121
XP_016884548 (OMIM: 606682,614073) PREDICTED: Herm ( 443) 2949 433.4 9.2e-121
XP_016884546 (OMIM: 606682,614073) PREDICTED: Herm ( 443) 2949 433.4 9.2e-121
XP_016884547 (OMIM: 606682,614073) PREDICTED: Herm ( 443) 2949 433.4 9.2e-121
XP_016884551 (OMIM: 606682,614073) PREDICTED: Herm ( 443) 2949 433.4 9.2e-121
XP_016884550 (OMIM: 606682,614073) PREDICTED: Herm ( 443) 2949 433.4 9.2e-121
XP_016884553 (OMIM: 606682,614073) PREDICTED: Herm ( 443) 2949 433.4 9.2e-121
XP_011528793 (OMIM: 606682,614073) PREDICTED: Herm ( 724) 2776 408.8 3.8e-113
XP_011528794 (OMIM: 606682,614073) PREDICTED: Herm ( 699) 2764 407.1 1.2e-112
XP_016884536 (OMIM: 606682,614073) PREDICTED: Herm ( 675) 2716 400.2 1.3e-110
XP_011528795 (OMIM: 606682,614073) PREDICTED: Herm ( 693) 2274 337.2 1.3e-91
>>XP_016884531 (OMIM: 606682,614073) PREDICTED: Hermansk (708 aa)
initn: 4727 init1: 4727 opt: 4727 Z-score: 3657.4 bits: 687.3 E(85289): 5.6e-197
Smith-Waterman score: 4727; 99.3% identity (99.9% similar) in 708 aa overlap (1-708:1-708)
10 20 30 40 50 60
pF1KA1 MATSTSTEAKSASWWNYFFLYDGSKVKEEGDPTRAGICYFYPSQTLLDQQELLCGQIAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MATSTSTEAKSASWWNYFFLYDGSKVKEEGDPTRAGICYFYPSQTLLDQQELLCGQIAGV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 VRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPDVSCKRFLDQLVGFFNFYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPDVSCKRFLDQLVGFFNFYN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 GPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSLWNLDQTKVEPLLLLKAARIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSLWNLDQTKVEPLLLLKAARIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 QTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRTAPQEQRLPTGGDAPQEHGAALP
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_016 QTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRTAPQEQRLPTGEDAPQEHGAALP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 PNVQIIPVFVTKEEAISLHEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNVQIIPVFVTKEEAISLHEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 VESMAWTTPDPTSPDEACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VESMAWTTPDPTSPDEACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 VFLQEELDLSEIHIPEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFLQEELDLSEIHIPEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 AISSLRPPSAPEMLTQHGAQEQVEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRG
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_016 AISSLRPPSAPEMLTQHGAQEQLEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 NKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 MNLYTHCVKGLMLSLLAEEPLLGDSAAIEEVYHSSLASLNGLEVHLKETLPRDEAASTSS
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNLYTHCVKGLVLSLLAEEPLLGDSAAIEEVYHSSLASLNGLEVHLKETLPRDEAASTSS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 TYNFTYYDRIQSLLMANLPQVATPHDRRFLQAVSLMHSEFAQLPALYEMTVRNASTAVYA
:::::.::::::::::::::::::.:::::::::::::::::::::::::::::::::::
XP_016 TYNFTHYDRIQSLLMANLPQVATPQDRRFLQAVSLMHSEFAQLPALYEMTVRNASTAVYA
610 620 630 640 650 660
670 680 690 700
pF1KA1 CCNPIQETYFQQLAPAARSSGFPNPQDGAFSLSGKAKQKLLKHGVNLL
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CCNPIQETYFQQLAPAARSSGFPNPQDGAFSLSGKAKQKLLKHGVNLL
670 680 690 700
>>NP_071364 (OMIM: 606682,614073) Hermansky-Pudlak syndr (708 aa)
initn: 4727 init1: 4727 opt: 4727 Z-score: 3657.4 bits: 687.3 E(85289): 5.6e-197
Smith-Waterman score: 4727; 99.3% identity (99.9% similar) in 708 aa overlap (1-708:1-708)
10 20 30 40 50 60
pF1KA1 MATSTSTEAKSASWWNYFFLYDGSKVKEEGDPTRAGICYFYPSQTLLDQQELLCGQIAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MATSTSTEAKSASWWNYFFLYDGSKVKEEGDPTRAGICYFYPSQTLLDQQELLCGQIAGV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 VRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPDVSCKRFLDQLVGFFNFYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 VRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPDVSCKRFLDQLVGFFNFYN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 GPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSLWNLDQTKVEPLLLLKAARIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 GPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSLWNLDQTKVEPLLLLKAARIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 QTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRTAPQEQRLPTGGDAPQEHGAALP
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
NP_071 QTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRTAPQEQRLPTGEDAPQEHGAALP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 PNVQIIPVFVTKEEAISLHEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 PNVQIIPVFVTKEEAISLHEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 VESMAWTTPDPTSPDEACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 VESMAWTTPDPTSPDEACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 VFLQEELDLSEIHIPEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 VFLQEELDLSEIHIPEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 AISSLRPPSAPEMLTQHGAQEQVEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRG
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
NP_071 AISSLRPPSAPEMLTQHGAQEQLEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 NKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 NKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 MNLYTHCVKGLMLSLLAEEPLLGDSAAIEEVYHSSLASLNGLEVHLKETLPRDEAASTSS
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MNLYTHCVKGLVLSLLAEEPLLGDSAAIEEVYHSSLASLNGLEVHLKETLPRDEAASTSS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 TYNFTYYDRIQSLLMANLPQVATPHDRRFLQAVSLMHSEFAQLPALYEMTVRNASTAVYA
:::::.::::::::::::::::::.:::::::::::::::::::::::::::::::::::
NP_071 TYNFTHYDRIQSLLMANLPQVATPQDRRFLQAVSLMHSEFAQLPALYEMTVRNASTAVYA
610 620 630 640 650 660
670 680 690 700
pF1KA1 CCNPIQETYFQQLAPAARSSGFPNPQDGAFSLSGKAKQKLLKHGVNLL
::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 CCNPIQETYFQQLAPAARSSGFPNPQDGAFSLSGKAKQKLLKHGVNLL
670 680 690 700
>>XP_016884533 (OMIM: 606682,614073) PREDICTED: Hermansk (708 aa)
initn: 4727 init1: 4727 opt: 4727 Z-score: 3657.4 bits: 687.3 E(85289): 5.6e-197
Smith-Waterman score: 4727; 99.3% identity (99.9% similar) in 708 aa overlap (1-708:1-708)
10 20 30 40 50 60
pF1KA1 MATSTSTEAKSASWWNYFFLYDGSKVKEEGDPTRAGICYFYPSQTLLDQQELLCGQIAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MATSTSTEAKSASWWNYFFLYDGSKVKEEGDPTRAGICYFYPSQTLLDQQELLCGQIAGV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 VRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPDVSCKRFLDQLVGFFNFYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPDVSCKRFLDQLVGFFNFYN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 GPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSLWNLDQTKVEPLLLLKAARIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSLWNLDQTKVEPLLLLKAARIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 QTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRTAPQEQRLPTGGDAPQEHGAALP
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_016 QTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRTAPQEQRLPTGEDAPQEHGAALP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 PNVQIIPVFVTKEEAISLHEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNVQIIPVFVTKEEAISLHEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 VESMAWTTPDPTSPDEACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VESMAWTTPDPTSPDEACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 VFLQEELDLSEIHIPEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFLQEELDLSEIHIPEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 AISSLRPPSAPEMLTQHGAQEQVEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRG
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_016 AISSLRPPSAPEMLTQHGAQEQLEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 NKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 MNLYTHCVKGLMLSLLAEEPLLGDSAAIEEVYHSSLASLNGLEVHLKETLPRDEAASTSS
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNLYTHCVKGLVLSLLAEEPLLGDSAAIEEVYHSSLASLNGLEVHLKETLPRDEAASTSS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 TYNFTYYDRIQSLLMANLPQVATPHDRRFLQAVSLMHSEFAQLPALYEMTVRNASTAVYA
:::::.::::::::::::::::::.:::::::::::::::::::::::::::::::::::
XP_016 TYNFTHYDRIQSLLMANLPQVATPQDRRFLQAVSLMHSEFAQLPALYEMTVRNASTAVYA
610 620 630 640 650 660
670 680 690 700
pF1KA1 CCNPIQETYFQQLAPAARSSGFPNPQDGAFSLSGKAKQKLLKHGVNLL
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CCNPIQETYFQQLAPAARSSGFPNPQDGAFSLSGKAKQKLLKHGVNLL
670 680 690 700
>>XP_016884532 (OMIM: 606682,614073) PREDICTED: Hermansk (708 aa)
initn: 4727 init1: 4727 opt: 4727 Z-score: 3657.4 bits: 687.3 E(85289): 5.6e-197
Smith-Waterman score: 4727; 99.3% identity (99.9% similar) in 708 aa overlap (1-708:1-708)
10 20 30 40 50 60
pF1KA1 MATSTSTEAKSASWWNYFFLYDGSKVKEEGDPTRAGICYFYPSQTLLDQQELLCGQIAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MATSTSTEAKSASWWNYFFLYDGSKVKEEGDPTRAGICYFYPSQTLLDQQELLCGQIAGV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 VRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPDVSCKRFLDQLVGFFNFYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPDVSCKRFLDQLVGFFNFYN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 GPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSLWNLDQTKVEPLLLLKAARIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSLWNLDQTKVEPLLLLKAARIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 QTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRTAPQEQRLPTGGDAPQEHGAALP
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_016 QTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRTAPQEQRLPTGEDAPQEHGAALP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 PNVQIIPVFVTKEEAISLHEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNVQIIPVFVTKEEAISLHEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 VESMAWTTPDPTSPDEACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VESMAWTTPDPTSPDEACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 VFLQEELDLSEIHIPEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFLQEELDLSEIHIPEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 AISSLRPPSAPEMLTQHGAQEQVEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRG
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_016 AISSLRPPSAPEMLTQHGAQEQLEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 NKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 MNLYTHCVKGLMLSLLAEEPLLGDSAAIEEVYHSSLASLNGLEVHLKETLPRDEAASTSS
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNLYTHCVKGLVLSLLAEEPLLGDSAAIEEVYHSSLASLNGLEVHLKETLPRDEAASTSS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 TYNFTYYDRIQSLLMANLPQVATPHDRRFLQAVSLMHSEFAQLPALYEMTVRNASTAVYA
:::::.::::::::::::::::::.:::::::::::::::::::::::::::::::::::
XP_016 TYNFTHYDRIQSLLMANLPQVATPQDRRFLQAVSLMHSEFAQLPALYEMTVRNASTAVYA
610 620 630 640 650 660
670 680 690 700
pF1KA1 CCNPIQETYFQQLAPAARSSGFPNPQDGAFSLSGKAKQKLLKHGVNLL
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CCNPIQETYFQQLAPAARSSGFPNPQDGAFSLSGKAKQKLLKHGVNLL
670 680 690 700
>>NP_690054 (OMIM: 606682,614073) Hermansky-Pudlak syndr (703 aa)
initn: 4644 init1: 4644 opt: 4644 Z-score: 3593.4 bits: 675.4 E(85289): 2e-193
Smith-Waterman score: 4644; 98.9% identity (99.6% similar) in 698 aa overlap (11-708:6-703)
10 20 30 40 50 60
pF1KA1 MATSTSTEAKSASWWNYFFLYDGSKVKEEGDPTRAGICYFYPSQTLLDQQELLCGQIAGV
: . ::::::::::::::::::::::::::::::::::::::::::::::
NP_690 MAPLCSLARWNYFFLYDGSKVKEEGDPTRAGICYFYPSQTLLDQQELLCGQIAGV
10 20 30 40 50
70 80 90 100 110 120
pF1KA1 VRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPDVSCKRFLDQLVGFFNFYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 VRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPDVSCKRFLDQLVGFFNFYN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KA1 GPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSLWNLDQTKVEPLLLLKAARIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 GPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSLWNLDQTKVEPLLLLKAARIL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KA1 QTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRTAPQEQRLPTGGDAPQEHGAALP
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
NP_690 QTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRTAPQEQRLPTGEDAPQEHGAALP
180 190 200 210 220 230
250 260 270 280 290 300
pF1KA1 PNVQIIPVFVTKEEAISLHEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 PNVQIIPVFVTKEEAISLHEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGH
240 250 260 270 280 290
310 320 330 340 350 360
pF1KA1 VESMAWTTPDPTSPDEACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 VESMAWTTPDPTSPDEACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKEL
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA1 VFLQEELDLSEIHIPEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 VFLQEELDLSEIHIPEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDT
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA1 AISSLRPPSAPEMLTQHGAQEQVEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRG
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
NP_690 AISSLRPPSAPEMLTQHGAQEQLEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRG
420 430 440 450 460 470
490 500 510 520 530 540
pF1KA1 NKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 NKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVR
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA1 MNLYTHCVKGLMLSLLAEEPLLGDSAAIEEVYHSSLASLNGLEVHLKETLPRDEAASTSS
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 MNLYTHCVKGLVLSLLAEEPLLGDSAAIEEVYHSSLASLNGLEVHLKETLPRDEAASTSS
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA1 TYNFTYYDRIQSLLMANLPQVATPHDRRFLQAVSLMHSEFAQLPALYEMTVRNASTAVYA
:::::.::::::::::::::::::.:::::::::::::::::::::::::::::::::::
NP_690 TYNFTHYDRIQSLLMANLPQVATPQDRRFLQAVSLMHSEFAQLPALYEMTVRNASTAVYA
600 610 620 630 640 650
670 680 690 700
pF1KA1 CCNPIQETYFQQLAPAARSSGFPNPQDGAFSLSGKAKQKLLKHGVNLL
::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 CCNPIQETYFQQLAPAARSSGFPNPQDGAFSLSGKAKQKLLKHGVNLL
660 670 680 690 700
>>XP_016884535 (OMIM: 606682,614073) PREDICTED: Hermansk (680 aa)
initn: 4351 init1: 4351 opt: 4358 Z-score: 3373.0 bits: 634.6 E(85289): 3.8e-181
Smith-Waterman score: 4358; 96.6% identity (97.8% similar) in 676 aa overlap (1-675:1-673)
10 20 30 40 50 60
pF1KA1 MATSTSTEAKSASWWNYFFLYDGSKVKEEGDPTRAGICYFYPSQTLLDQQELLCGQIAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MATSTSTEAKSASWWNYFFLYDGSKVKEEGDPTRAGICYFYPSQTLLDQQELLCGQIAGV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 VRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPDVSCKRFLDQLVGFFNFYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPDVSCKRFLDQLVGFFNFYN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 GPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSLWNLDQTKVEPLLLLKAARIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSLWNLDQTKVEPLLLLKAARIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 QTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRTAPQEQRLPTGGDAPQEHGAALP
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_016 QTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRTAPQEQRLPTGEDAPQEHGAALP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 PNVQIIPVFVTKEEAISLHEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNVQIIPVFVTKEEAISLHEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 VESMAWTTPDPTSPDEACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VESMAWTTPDPTSPDEACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 VFLQEELDLSEIHIPEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFLQEELDLSEIHIPEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 AISSLRPPSAPEMLTQHGAQEQVEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRG
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_016 AISSLRPPSAPEMLTQHGAQEQLEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 NKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 MNLYTHCVKGLMLSLLAEEPLLGDSAAIEEVYHSSLASLNGLEVHLKETLPRDEAASTSS
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNLYTHCVKGLVLSLLAEEPLLGDSAAIEEVYHSSLASLNGLEVHLKETLPRDEAASTSS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 TYNFTYYDRIQSLLMANLPQVATPHDRRFLQAVSLMHSEFAQLPALYEMTVRNASTAVYA
:::::.::::::::::::::::::.::::::::::::::::::::::::::: : .
XP_016 TYNFTHYDRIQSLLMANLPQVATPQDRRFLQAVSLMHSEFAQLPALYEMTVR---LPVTS
610 620 630 640 650
670 680 690 700
pF1KA1 CCNPIQE-TYFQQLAPAARSSGFPNPQDGAFSLSGKAKQKLLKHGVNLL
: :. : :.. :
XP_016 CHIPLLSFTPSQSIQPPPVWRAD
660 670 680
>>XP_016884538 (OMIM: 606682,614073) PREDICTED: Hermansk (655 aa)
initn: 4405 init1: 4346 opt: 4346 Z-score: 3364.0 bits: 632.9 E(85289): 1.2e-180
Smith-Waterman score: 4346; 98.8% identity (99.5% similar) in 655 aa overlap (1-655:1-655)
10 20 30 40 50 60
pF1KA1 MATSTSTEAKSASWWNYFFLYDGSKVKEEGDPTRAGICYFYPSQTLLDQQELLCGQIAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MATSTSTEAKSASWWNYFFLYDGSKVKEEGDPTRAGICYFYPSQTLLDQQELLCGQIAGV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 VRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPDVSCKRFLDQLVGFFNFYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPDVSCKRFLDQLVGFFNFYN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 GPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSLWNLDQTKVEPLLLLKAARIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSLWNLDQTKVEPLLLLKAARIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 QTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRTAPQEQRLPTGGDAPQEHGAALP
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_016 QTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRTAPQEQRLPTGEDAPQEHGAALP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 PNVQIIPVFVTKEEAISLHEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNVQIIPVFVTKEEAISLHEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 VESMAWTTPDPTSPDEACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VESMAWTTPDPTSPDEACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 VFLQEELDLSEIHIPEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFLQEELDLSEIHIPEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 AISSLRPPSAPEMLTQHGAQEQVEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRG
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_016 AISSLRPPSAPEMLTQHGAQEQLEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 NKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 MNLYTHCVKGLMLSLLAEEPLLGDSAAIEEVYHSSLASLNGLEVHLKETLPRDEAASTSS
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNLYTHCVKGLVLSLLAEEPLLGDSAAIEEVYHSSLASLNGLEVHLKETLPRDEAASTSS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 TYNFTYYDRIQSLLMANLPQVATPHDRRFLQAVSLMHSEFAQLPALYEMTVRNASTAVYA
:::::.::::::::::::::::::.:::::::::::::::::::::::::: .:
XP_016 TYNFTHYDRIQSLLMANLPQVATPQDRRFLQAVSLMHSEFAQLPALYEMTVSCTS
610 620 630 640 650
670 680 690 700
pF1KA1 CCNPIQETYFQQLAPAARSSGFPNPQDGAFSLSGKAKQKLLKHGVNLL
>>XP_016884537 (OMIM: 606682,614073) PREDICTED: Hermansk (655 aa)
initn: 4405 init1: 4346 opt: 4346 Z-score: 3364.0 bits: 632.9 E(85289): 1.2e-180
Smith-Waterman score: 4346; 98.8% identity (99.5% similar) in 655 aa overlap (1-655:1-655)
10 20 30 40 50 60
pF1KA1 MATSTSTEAKSASWWNYFFLYDGSKVKEEGDPTRAGICYFYPSQTLLDQQELLCGQIAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MATSTSTEAKSASWWNYFFLYDGSKVKEEGDPTRAGICYFYPSQTLLDQQELLCGQIAGV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 VRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPDVSCKRFLDQLVGFFNFYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPDVSCKRFLDQLVGFFNFYN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 GPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSLWNLDQTKVEPLLLLKAARIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSLWNLDQTKVEPLLLLKAARIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 QTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRTAPQEQRLPTGGDAPQEHGAALP
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_016 QTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRTAPQEQRLPTGEDAPQEHGAALP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 PNVQIIPVFVTKEEAISLHEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNVQIIPVFVTKEEAISLHEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 VESMAWTTPDPTSPDEACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VESMAWTTPDPTSPDEACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 VFLQEELDLSEIHIPEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFLQEELDLSEIHIPEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 AISSLRPPSAPEMLTQHGAQEQVEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRG
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_016 AISSLRPPSAPEMLTQHGAQEQLEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 NKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 MNLYTHCVKGLMLSLLAEEPLLGDSAAIEEVYHSSLASLNGLEVHLKETLPRDEAASTSS
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNLYTHCVKGLVLSLLAEEPLLGDSAAIEEVYHSSLASLNGLEVHLKETLPRDEAASTSS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 TYNFTYYDRIQSLLMANLPQVATPHDRRFLQAVSLMHSEFAQLPALYEMTVRNASTAVYA
:::::.::::::::::::::::::.:::::::::::::::::::::::::: .:
XP_016 TYNFTHYDRIQSLLMANLPQVATPQDRRFLQAVSLMHSEFAQLPALYEMTVSCTS
610 620 630 640 650
670 680 690 700
pF1KA1 CCNPIQETYFQQLAPAARSSGFPNPQDGAFSLSGKAKQKLLKHGVNLL
>>XP_016884540 (OMIM: 606682,614073) PREDICTED: Hermansk (649 aa)
initn: 3849 init1: 3849 opt: 3856 Z-score: 2986.1 bits: 562.9 E(85289): 1.4e-159
Smith-Waterman score: 3856; 96.0% identity (97.0% similar) in 603 aa overlap (1-601:1-597)
10 20 30 40 50 60
pF1KA1 MATSTSTEAKSASWWNYFFLYDGSKVKEEGDPTRAGICYFYPSQTLLDQQELLCGQIAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MATSTSTEAKSASWWNYFFLYDGSKVKEEGDPTRAGICYFYPSQTLLDQQELLCGQIAGV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 VRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPDVSCKRFLDQLVGFFNFYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPDVSCKRFLDQLVGFFNFYN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 GPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSLWNLDQTKVEPLLLLKAARIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSLWNLDQTKVEPLLLLKAARIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 QTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRTAPQEQRLPTGGDAPQEHGAALP
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_016 QTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRTAPQEQRLPTGEDAPQEHGAALP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 PNVQIIPVFVTKEEAISLHEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNVQIIPVFVTKEEAISLHEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 VESMAWTTPDPTSPDEACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VESMAWTTPDPTSPDEACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 VFLQEELDLSEIHIPEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFLQEELDLSEIHIPEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 AISSLRPPSAPEMLTQHGAQEQVEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRG
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_016 AISSLRPPSAPEMLTQHGAQEQLEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 NKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVR
490 500 510 520 530 540
550 560 570 580 590
pF1KA1 MNLYTHCVKGLMLSLLAEEPLLGDSAAIEEVYHSSLASLNGLEVHLKETLPRD--EAAST
:::::::::::.::::::::::::::::::: :.: :.: . : : ::.:
XP_016 MNLYTHCVKGLVLSLLAEEPLLGDSAAIEEV-----KCLHGC-VRLLQPHPGDIFPAAGT
550 560 570 580 590
600 610 620 630 640 650
pF1KA1 SSTYNFTYYDRIQSLLMANLPQVATPHDRRFLQAVSLMHSEFAQLPALYEMTVRNASTAV
::
XP_016 CSTELRLPKPSGWRLQPLRQSKAEAAEARGELALNCTQEVTGKEKTSKGSSAFYN
600 610 620 630 640
>>XP_016884539 (OMIM: 606682,614073) PREDICTED: Hermansk (649 aa)
initn: 3849 init1: 3849 opt: 3856 Z-score: 2986.1 bits: 562.9 E(85289): 1.4e-159
Smith-Waterman score: 3856; 96.0% identity (97.0% similar) in 603 aa overlap (1-601:1-597)
10 20 30 40 50 60
pF1KA1 MATSTSTEAKSASWWNYFFLYDGSKVKEEGDPTRAGICYFYPSQTLLDQQELLCGQIAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MATSTSTEAKSASWWNYFFLYDGSKVKEEGDPTRAGICYFYPSQTLLDQQELLCGQIAGV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 VRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPDVSCKRFLDQLVGFFNFYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPDVSCKRFLDQLVGFFNFYN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 GPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSLWNLDQTKVEPLLLLKAARIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSLWNLDQTKVEPLLLLKAARIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 QTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRTAPQEQRLPTGGDAPQEHGAALP
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_016 QTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRTAPQEQRLPTGEDAPQEHGAALP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 PNVQIIPVFVTKEEAISLHEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNVQIIPVFVTKEEAISLHEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 VESMAWTTPDPTSPDEACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VESMAWTTPDPTSPDEACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 VFLQEELDLSEIHIPEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFLQEELDLSEIHIPEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 AISSLRPPSAPEMLTQHGAQEQVEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRG
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_016 AISSLRPPSAPEMLTQHGAQEQLEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 NKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVR
490 500 510 520 530 540
550 560 570 580 590
pF1KA1 MNLYTHCVKGLMLSLLAEEPLLGDSAAIEEVYHSSLASLNGLEVHLKETLPRD--EAAST
:::::::::::.::::::::::::::::::: :.: :.: . : : ::.:
XP_016 MNLYTHCVKGLVLSLLAEEPLLGDSAAIEEV-----KCLHGC-VRLLQPHPGDIFPAAGT
550 560 570 580 590
600 610 620 630 640 650
pF1KA1 SSTYNFTYYDRIQSLLMANLPQVATPHDRRFLQAVSLMHSEFAQLPALYEMTVRNASTAV
::
XP_016 CSTELRLPKPSGWRLQPLRQSKAEAAEARGELALNCTQEVTGKEKTSKGSSAFYN
600 610 620 630 640
708 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 01:42:01 2016 done: Fri Nov 4 01:42:02 2016
Total Scan time: 10.020 Total Display time: 0.170
Function used was FASTA [36.3.4 Apr, 2011]