FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1675, 1276 aa 1>>>pF1KA1675 1276 - 1276 aa - 1276 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.3368+/-0.000476; mu= -8.4602+/- 0.030 mean_var=575.3148+/-120.223, 0's: 0 Z-trim(121.8): 1379 B-trim: 0 in 0/61 Lambda= 0.053471 statistics sampled from 37257 (38985) to 37257 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.752), E-opt: 0.2 (0.457), width: 16 Scan time: 18.750 The best scores are: opt bits E(85289) NP_071397 (OMIM: 605557,615373) PR domain zinc fin (1276) 8833 697.8 1.2e-199 XP_005244829 (OMIM: 605557,615373) PREDICTED: PR d (1277) 8821 696.9 2.2e-199 XP_016857539 (OMIM: 605557,615373) PREDICTED: PR d (1275) 8816 696.5 2.9e-199 XP_006710877 (OMIM: 605557,615373) PREDICTED: PR d (1276) 8804 695.6 5.5e-199 NP_955533 (OMIM: 605557,615373) PR domain zinc fin (1257) 8541 675.3 7e-193 XP_005244830 (OMIM: 605557,615373) PREDICTED: PR d (1258) 8529 674.4 1.3e-192 XP_005244831 (OMIM: 605557,615373) PREDICTED: PR d (1178) 8146 644.8 1e-183 XP_011540247 (OMIM: 605557,615373) PREDICTED: PR d (1092) 7573 600.6 1.9e-170 XP_005247272 (OMIM: 165215,616738) PREDICTED: MDS1 (1230) 2067 175.9 1.5e-42 XP_005247271 (OMIM: 165215,616738) PREDICTED: MDS1 (1231) 2055 175.0 2.9e-42 NP_004982 (OMIM: 165215,616738) MDS1 and EVI1 comp (1239) 1929 165.2 2.4e-39 XP_011510848 (OMIM: 165215,616738) PREDICTED: MDS1 (1124) 1927 165.0 2.6e-39 XP_016861363 (OMIM: 165215,616738) PREDICTED: MDS1 (1116) 1916 164.2 4.6e-39 NP_001098547 (OMIM: 165215,616738) MDS1 and EVI1 c (1116) 1916 164.2 4.6e-39 XP_005247270 (OMIM: 165215,616738) PREDICTED: MDS1 (1240) 1917 164.3 4.6e-39 XP_016861364 (OMIM: 165215,616738) PREDICTED: MDS1 (1042) 1824 157.1 6e-37 NP_001157472 (OMIM: 165215,616738) MDS1 and EVI1 c (1042) 1824 157.1 6e-37 XP_016861365 (OMIM: 165215,616738) PREDICTED: MDS1 (1043) 1812 156.1 1.1e-36 NP_001157471 (OMIM: 165215,616738) MDS1 and EVI1 c (1043) 1812 156.1 1.1e-36 XP_005247280 (OMIM: 165215,616738) PREDICTED: MDS1 (1051) 1686 146.4 9.6e-34 NP_005232 (OMIM: 165215,616738) MDS1 and EVI1 comp (1051) 1686 146.4 9.6e-34 NP_001192123 (OMIM: 165215,616738) MDS1 and EVI1 c (1051) 1686 146.4 9.6e-34 NP_001098548 (OMIM: 165215,616738) MDS1 and EVI1 c (1051) 1686 146.4 9.6e-34 XP_005247278 (OMIM: 165215,616738) PREDICTED: MDS1 (1052) 1674 145.5 1.8e-33 XP_005247277 (OMIM: 165215,616738) PREDICTED: MDS1 (1052) 1674 145.5 1.8e-33 XP_005247276 (OMIM: 165215,616738) PREDICTED: MDS1 (1052) 1674 145.5 1.8e-33 XP_016861367 (OMIM: 165215,616738) PREDICTED: MDS1 ( 718) 1355 120.7 3.6e-26 XP_005247283 (OMIM: 165215,616738) PREDICTED: MDS1 ( 906) 1355 120.8 4.2e-26 XP_016861366 (OMIM: 165215,616738) PREDICTED: MDS1 ( 907) 1355 120.8 4.3e-26 XP_005247281 (OMIM: 165215,616738) PREDICTED: MDS1 ( 916) 1325 118.5 2.1e-25 XP_005247282 (OMIM: 165215,616738) PREDICTED: MDS1 ( 915) 1128 103.3 8e-21 XP_016867181 (OMIM: 604756) PREDICTED: zinc finger ( 504) 573 60.2 4.2e-08 XP_016867184 (OMIM: 604756) PREDICTED: zinc finger ( 504) 573 60.2 4.2e-08 XP_016867185 (OMIM: 604756) PREDICTED: zinc finger ( 504) 573 60.2 4.2e-08 XP_016867180 (OMIM: 604756) PREDICTED: zinc finger ( 504) 573 60.2 4.2e-08 XP_016867182 (OMIM: 604756) PREDICTED: zinc finger ( 504) 573 60.2 4.2e-08 XP_016867179 (OMIM: 604756) PREDICTED: zinc finger ( 504) 573 60.2 4.2e-08 XP_016867178 (OMIM: 604756) PREDICTED: zinc finger ( 504) 573 60.2 4.2e-08 XP_016867183 (OMIM: 604756) PREDICTED: zinc finger ( 504) 573 60.2 4.2e-08 XP_016867186 (OMIM: 604756) PREDICTED: zinc finger ( 504) 573 60.2 4.2e-08 XP_016867187 (OMIM: 604756) PREDICTED: zinc finger ( 504) 573 60.2 4.2e-08 XP_011514048 (OMIM: 604756) PREDICTED: zinc finger ( 537) 573 60.2 4.3e-08 NP_066971 (OMIM: 604756) zinc finger protein 273 [ ( 569) 573 60.2 4.5e-08 XP_016867177 (OMIM: 604756) PREDICTED: zinc finger ( 569) 573 60.2 4.5e-08 XP_011513163 (OMIM: 602277) PREDICTED: zinc finger ( 675) 572 60.3 5.3e-08 NP_001305822 (OMIM: 602277) zinc finger protein 18 ( 675) 572 60.3 5.3e-08 NP_001305820 (OMIM: 602277) zinc finger protein 18 ( 751) 572 60.3 5.7e-08 NP_001305821 (OMIM: 602277) zinc finger protein 18 ( 751) 572 60.3 5.7e-08 NP_009080 (OMIM: 602277) zinc finger protein 184 i ( 751) 572 60.3 5.7e-08 XP_016884975 (OMIM: 300498,314998) PREDICTED: zinc ( 661) 566 59.8 7.2e-08 >>NP_071397 (OMIM: 605557,615373) PR domain zinc finger (1276 aa) initn: 8833 init1: 8833 opt: 8833 Z-score: 3705.5 bits: 697.8 E(85289): 1.2e-199 Smith-Waterman score: 8833; 99.9% identity (99.9% similar) in 1276 aa overlap (1-1276:1-1276) 10 20 30 40 50 60 pF1KA1 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 AKETDFGWEQILTDVEVSPQEGCITKISEDLGSEKFCVDANQAGAGSWLKYIRVACSCDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 AKETDFGWEQILTDVEVSPQEGCITKISEDLGSEKFCVDANQAGAGSWLKYIRVACSCDD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 QNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELFQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 SKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 SKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQHM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 VIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 VIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 VGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 VGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADCR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 TQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 TQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLNH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTPLLKSPLN :::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::: NP_071 ASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTSLLKSPLN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 HTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 HTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMSD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 GSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 GSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAPN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 SVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 SVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSLP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 YHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 YHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKPK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 DVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 DVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGLP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 QVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 QVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMSA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 IETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 IETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKIF 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 PRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 PRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQQ 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 TNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 TNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNFI 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 ANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 ANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQD 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 DTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 DTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLRR 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 AAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 AAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLKV 1210 1220 1230 1240 1250 1260 1270 pF1KA1 TGATSESGAFHPINHL :::::::::::::::: NP_071 TGATSESGAFHPINHL 1270 >>XP_005244829 (OMIM: 605557,615373) PREDICTED: PR domai (1277 aa) initn: 7840 init1: 7840 opt: 8821 Z-score: 3700.4 bits: 696.9 E(85289): 2.2e-199 Smith-Waterman score: 8821; 99.8% identity (99.8% similar) in 1277 aa overlap (1-1276:1-1277) 10 20 30 40 50 60 pF1KA1 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA 70 80 90 100 110 120 130 140 150 160 170 pF1KA1 AKETDFGWEQILTDVEVSPQEGCITK-ISEDLGSEKFCVDANQAGAGSWLKYIRVACSCD :::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::: XP_005 AKETDFGWEQILTDVEVSPQEGCITKQISEDLGSEKFCVDANQAGAGSWLKYIRVACSCD 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA1 DQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA1 QSKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QSKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQH 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA1 MVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA1 HVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADC 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA1 RTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLN 430 440 450 460 470 480 480 490 500 510 520 530 pF1KA1 HASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTPLLKSPL ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::: XP_005 HASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTSLLKSPL 490 500 510 520 530 540 540 550 560 570 580 590 pF1KA1 NHTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NHTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMS 550 560 570 580 590 600 600 610 620 630 640 650 pF1KA1 DGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAP 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA1 NSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSL 670 680 690 700 710 720 720 730 740 750 760 770 pF1KA1 PYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKP 730 740 750 760 770 780 780 790 800 810 820 830 pF1KA1 KDVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KDVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGL 790 800 810 820 830 840 840 850 860 870 880 890 pF1KA1 PQVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMS 850 860 870 880 890 900 900 910 920 930 940 950 pF1KA1 AIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKI 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KA1 FPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQ 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KA1 QTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNF 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KA1 IANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQ 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KA1 DDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLR 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KA1 RAAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RAAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLK 1210 1220 1230 1240 1250 1260 1260 1270 pF1KA1 VTGATSESGAFHPINHL ::::::::::::::::: XP_005 VTGATSESGAFHPINHL 1270 >>XP_016857539 (OMIM: 605557,615373) PREDICTED: PR domai (1275 aa) initn: 8814 init1: 6062 opt: 8816 Z-score: 3698.4 bits: 696.5 E(85289): 2.9e-199 Smith-Waterman score: 8816; 99.8% identity (99.8% similar) in 1276 aa overlap (1-1276:1-1275) 10 20 30 40 50 60 pF1KA1 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 AKETDFGWEQILTDVEVSPQEGCITKISEDLGSEKFCVDANQAGAGSWLKYIRVACSCDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKETDFGWEQILTDVEVSPQEGCITKISEDLGSEKFCVDANQAGAGSWLKYIRVACSCDD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELFQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 SKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQHM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 VIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 VGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADCR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 TQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLNH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTPLLKSPLN :::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::: XP_016 ASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTSLLKSPLN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 HTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMSD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 GSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAPN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 SVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSLP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 YHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKPK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 DVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGLP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 QVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMSA ::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::: XP_016 QVCPARMPQQPPLHYAKPSPFFMDPIY-RVEKRKVTDPVGALKEKYLRPSPLLFHPQMSA 850 860 870 880 890 910 920 930 940 950 960 pF1KA1 IETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKIF 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KA1 PRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQQ 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KA1 TNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNFI 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KA1 ANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQD 1080 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 pF1KA1 DTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLRR 1140 1150 1160 1170 1180 1190 1210 1220 1230 1240 1250 1260 pF1KA1 AAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLKV 1200 1210 1220 1230 1240 1250 1270 pF1KA1 TGATSESGAFHPINHL :::::::::::::::: XP_016 TGATSESGAFHPINHL 1260 1270 >>XP_006710877 (OMIM: 605557,615373) PREDICTED: PR domai (1276 aa) initn: 5069 init1: 5069 opt: 8804 Z-score: 3693.4 bits: 695.6 E(85289): 5.5e-199 Smith-Waterman score: 8804; 99.8% identity (99.8% similar) in 1277 aa overlap (1-1276:1-1276) 10 20 30 40 50 60 pF1KA1 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA 70 80 90 100 110 120 130 140 150 160 170 pF1KA1 AKETDFGWEQILTDVEVSPQEGCITK-ISEDLGSEKFCVDANQAGAGSWLKYIRVACSCD :::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::: XP_006 AKETDFGWEQILTDVEVSPQEGCITKQISEDLGSEKFCVDANQAGAGSWLKYIRVACSCD 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA1 DQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA1 QSKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QSKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQH 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA1 MVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA1 HVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADC 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA1 RTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLN 430 440 450 460 470 480 480 490 500 510 520 530 pF1KA1 HASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTPLLKSPL ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::: XP_006 HASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTSLLKSPL 490 500 510 520 530 540 540 550 560 570 580 590 pF1KA1 NHTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NHTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMS 550 560 570 580 590 600 600 610 620 630 640 650 pF1KA1 DGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAP 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA1 NSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSL 670 680 690 700 710 720 720 730 740 750 760 770 pF1KA1 PYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKP 730 740 750 760 770 780 780 790 800 810 820 830 pF1KA1 KDVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KDVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGL 790 800 810 820 830 840 840 850 860 870 880 890 pF1KA1 PQVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMS :::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::: XP_006 PQVCPARMPQQPPLHYAKPSPFFMDPIY-RVEKRKVTDPVGALKEKYLRPSPLLFHPQMS 850 860 870 880 890 900 910 920 930 940 950 pF1KA1 AIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKI 900 910 920 930 940 950 960 970 980 990 1000 1010 pF1KA1 FPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQ 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KA1 QTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNF 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 pF1KA1 IANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQ 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 pF1KA1 DDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLR 1140 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 pF1KA1 RAAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RAAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLK 1200 1210 1220 1230 1240 1250 1260 1270 pF1KA1 VTGATSESGAFHPINHL ::::::::::::::::: XP_006 VTGATSESGAFHPINHL 1260 1270 >>NP_955533 (OMIM: 605557,615373) PR domain zinc finger (1257 aa) initn: 8541 init1: 8541 opt: 8541 Z-score: 3583.8 bits: 675.3 E(85289): 7e-193 Smith-Waterman score: 8662; 98.4% identity (98.4% similar) in 1276 aa overlap (1-1276:1-1257) 10 20 30 40 50 60 pF1KA1 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_955 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_955 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 AKETDFGWEQILTDVEVSPQEGCITKISEDLGSEKFCVDANQAGAGSWLKYIRVACSCDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_955 AKETDFGWEQILTDVEVSPQEGCITKISEDLGSEKFCVDANQAGAGSWLKYIRVACSCDD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_955 QNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELFQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 SKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_955 SKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQHM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 VIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_955 VIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 VGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_955 VGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADCR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 TQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_955 TQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLNH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTPLLKSPLN :::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::: NP_955 ASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTSLLKSPLN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 HTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_955 HTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMSD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 GSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_955 GSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAPN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 SVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_955 SVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSLP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 YHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_955 YHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKPK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 DVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_955 DVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGLP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 QVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_955 QVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMSA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 IETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_955 IETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKIF 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 PRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_955 PRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQQ 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 TNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_955 TNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNFI 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 ANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_955 ANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQD 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 DTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_955 DTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLRR 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 AAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLKV :::::::::::::::::::::::::::::::: ::::::::: NP_955 AAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQ-------------------GSLDAWLKV 1210 1220 1230 1240 1270 pF1KA1 TGATSESGAFHPINHL :::::::::::::::: NP_955 TGATSESGAFHPINHL 1250 >>XP_005244830 (OMIM: 605557,615373) PREDICTED: PR domai (1258 aa) initn: 7548 init1: 7548 opt: 8529 Z-score: 3578.8 bits: 674.4 E(85289): 1.3e-192 Smith-Waterman score: 8650; 98.4% identity (98.4% similar) in 1277 aa overlap (1-1276:1-1258) 10 20 30 40 50 60 pF1KA1 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA 70 80 90 100 110 120 130 140 150 160 170 pF1KA1 AKETDFGWEQILTDVEVSPQEGCITK-ISEDLGSEKFCVDANQAGAGSWLKYIRVACSCD :::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::: XP_005 AKETDFGWEQILTDVEVSPQEGCITKQISEDLGSEKFCVDANQAGAGSWLKYIRVACSCD 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA1 DQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA1 QSKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QSKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQH 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA1 MVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA1 HVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADC 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA1 RTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLN 430 440 450 460 470 480 480 490 500 510 520 530 pF1KA1 HASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTPLLKSPL ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::: XP_005 HASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTSLLKSPL 490 500 510 520 530 540 540 550 560 570 580 590 pF1KA1 NHTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NHTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMS 550 560 570 580 590 600 600 610 620 630 640 650 pF1KA1 DGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAP 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA1 NSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSL 670 680 690 700 710 720 720 730 740 750 760 770 pF1KA1 PYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKP 730 740 750 760 770 780 780 790 800 810 820 830 pF1KA1 KDVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KDVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGL 790 800 810 820 830 840 840 850 860 870 880 890 pF1KA1 PQVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMS 850 860 870 880 890 900 900 910 920 930 940 950 pF1KA1 AIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKI 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KA1 FPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQ 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KA1 QTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNF 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KA1 IANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQ 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KA1 DDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLR 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KA1 RAAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLK ::::::::::::::::::::::::::::::::: :::::::: XP_005 RAAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQ-------------------GSLDAWLK 1210 1220 1230 1240 1260 1270 pF1KA1 VTGATSESGAFHPINHL ::::::::::::::::: XP_005 VTGATSESGAFHPINHL 1250 >>XP_005244831 (OMIM: 605557,615373) PREDICTED: PR domai (1178 aa) initn: 7165 init1: 7165 opt: 8146 Z-score: 3419.4 bits: 644.8 E(85289): 1e-183 Smith-Waterman score: 8146; 99.8% identity (99.8% similar) in 1175 aa overlap (1-1174:1-1175) 10 20 30 40 50 60 pF1KA1 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA 70 80 90 100 110 120 130 140 150 160 170 pF1KA1 AKETDFGWEQILTDVEVSPQEGCITK-ISEDLGSEKFCVDANQAGAGSWLKYIRVACSCD :::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::: XP_005 AKETDFGWEQILTDVEVSPQEGCITKQISEDLGSEKFCVDANQAGAGSWLKYIRVACSCD 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA1 DQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA1 QSKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QSKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQH 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA1 MVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA1 HVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADC 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA1 RTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLN 430 440 450 460 470 480 480 490 500 510 520 530 pF1KA1 HASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTPLLKSPL ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::: XP_005 HASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTSLLKSPL 490 500 510 520 530 540 540 550 560 570 580 590 pF1KA1 NHTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NHTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMS 550 560 570 580 590 600 600 610 620 630 640 650 pF1KA1 DGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAP 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA1 NSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSL 670 680 690 700 710 720 720 730 740 750 760 770 pF1KA1 PYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKP 730 740 750 760 770 780 780 790 800 810 820 830 pF1KA1 KDVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KDVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGL 790 800 810 820 830 840 840 850 860 870 880 890 pF1KA1 PQVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMS 850 860 870 880 890 900 900 910 920 930 940 950 pF1KA1 AIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKI 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KA1 FPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQ 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KA1 QTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNF 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KA1 IANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQ 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KA1 DDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLR ::::::::::::::::::::::::::::::::::: XP_005 DDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRHMQ 1150 1160 1170 1200 1210 1220 1230 1240 1250 pF1KA1 RAAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLK >>XP_011540247 (OMIM: 605557,615373) PREDICTED: PR domai (1092 aa) initn: 7573 init1: 7573 opt: 7573 Z-score: 3180.9 bits: 600.6 E(85289): 1.9e-170 Smith-Waterman score: 7573; 99.9% identity (99.9% similar) in 1092 aa overlap (185-1276:1-1092) 160 170 180 190 200 210 pF1KA1 KFCVDANQAGAGSWLKYIRVACSCDDQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGV :::::::::::::::::::::::::::::: XP_011 MCQISEQIYYKVIKDIEPGEELLVHVKEGV 10 20 30 220 230 240 250 260 270 pF1KA1 YPLGTVPPGLDEEPTFRCDECDELFQSKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YPLGTVPPGLDEEPTFRCDECDELFQSKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLG 40 50 60 70 80 90 280 290 300 310 320 330 pF1KA1 GGSGQAHECKDCERMFPNKYSLEQHMVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGSGQAHECKDCERMFPNKYSLEQHMVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSG 100 110 120 130 140 150 340 350 360 370 380 390 pF1KA1 KRFECENCVKVFTDPSNLQRHIRSQHVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRFECENCVKVFTDPSNLQRHIRSQHVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPF 160 170 180 190 200 210 400 410 420 430 440 450 pF1KA1 ICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPG 220 230 240 250 260 270 460 470 480 490 500 510 pF1KA1 GIFAPGLPLTPSPMMDKAKPSPSLNHASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GIFAPGLPLTPSPMMDKAKPSPSLNHASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGF 280 290 300 310 320 330 520 530 540 550 560 570 pF1KA1 PGIFPPSLYPRPPLLPPTPLLKSPLNHTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAG :::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::: XP_011 PGIFPPSLYPRPPLLPPTSLLKSPLNHTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAG 340 350 360 370 380 390 580 590 600 610 620 630 pF1KA1 PEEKFESRLEDSCVEKLKTRSSDMSDGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEEKFESRLEDSCVEKLKTRSSDMSDGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPD 400 410 420 430 440 450 640 650 660 670 680 690 pF1KA1 KDKGKGKSAEGQPKFGGGLAPPGAPNSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDKGKGKSAEGQPKFGGGLAPPGAPNSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIK 460 470 480 490 500 510 700 710 720 730 740 750 pF1KA1 AIASIAEKYFGPGFMGMQEKKLGSLPYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AIASIAEKYFGPGFMGMQEKKLGSLPYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAE 520 530 540 550 560 570 760 770 780 790 800 810 pF1KA1 PKSPRDALKVGGPSAECPFDLTTKPKDVKPILPMPKGPSAPASGEEQPLDLSIGSRARAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKSPRDALKVGGPSAECPFDLTTKPKDVKPILPMPKGPSAPASGEEQPLDLSIGSRARAS 580 590 600 610 620 630 820 830 840 850 860 870 pF1KA1 QNGGGREPRKNHVYGERKLGAGEGLPQVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QNGGGREPRKNHVYGERKLGAGEGLPQVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRK 640 650 660 670 680 690 880 890 900 910 920 930 pF1KA1 VTDPVGALKEKYLRPSPLLFHPQMSAIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTDPVGALKEKYLRPSPLLFHPQMSAIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRS 700 710 720 730 740 750 940 950 960 970 980 990 pF1KA1 PPPTLSDPILRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPPTLSDPILRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNL 760 770 780 790 800 810 1000 1010 1020 1030 1040 1050 pF1KA1 QRHVRNIHNKEKPFKCHLCNRCFGQQTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRHVRNIHNKEKPFKCHLCNRCFGQQTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASS 820 830 840 850 860 870 1060 1070 1080 1090 1100 1110 pF1KA1 PTSESDNHALLDEKEDSYFSEIRNFIANSEMNQASTRTEKRADMQIVDGSAQCPGLASEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTSESDNHALLDEKEDSYFSEIRNFIANSEMNQASTRTEKRADMQIVDGSAQCPGLASEK 880 890 900 910 920 930 1120 1130 1140 1150 1160 1170 pF1KA1 QEDVEEEDDDDLEEDDEDSLAGKSQDDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QEDVEEEDDDDLEEDDEDSLAGKSQDDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRR 940 950 960 970 980 990 1180 1190 1200 1210 1220 1230 pF1KA1 CAEDHEGGLLALEPMPTFGKGLDLRRAAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CAEDHEGGLLALEPMPTFGKGLDLRRAAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAY 1000 1010 1020 1030 1040 1050 1240 1250 1260 1270 pF1KA1 AMMLSLSEDTPLHTPSQGSLDAWLKVTGATSESGAFHPINHL :::::::::::::::::::::::::::::::::::::::::: XP_011 AMMLSLSEDTPLHTPSQGSLDAWLKVTGATSESGAFHPINHL 1060 1070 1080 1090 >>XP_005247272 (OMIM: 165215,616738) PREDICTED: MDS1 and (1230 aa) initn: 3393 init1: 1228 opt: 2067 Z-score: 884.8 bits: 175.9 E(85289): 1.5e-42 Smith-Waterman score: 4259; 52.6% identity (74.2% similar) in 1293 aa overlap (1-1276:1-1230) 10 20 30 40 50 pF1KA1 MRSKARARKLAKSDGDVVNNMYE-PNRDLLASHSAEDEAEDSAMSP-IPVGPP-SPFPTS ::::.:::::: .. : .:. : : ... .:. : .: . . : :: .: XP_005 MRSKGRARKLATNNECVYGNYPEIPLEEM-------PDADGVASTPSLNIQEPCSPATSS 10 20 30 40 50 60 70 80 90 100 110 pF1KA1 EDFTPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVP : :::::::::.::.:::.::::::.::::::..::::::.:.:::.:.::..:: : XP_005 EAFTPKEGSPYKAPIYIPDDIPIPAEFELRESNMPGAGLGIWTKRKIEVGEKFGPYVGEQ 60 70 80 90 100 110 120 130 140 150 160 170 pF1KA1 RAAAKETDFGWEQILTDVEVSPQEGCITKISEDLGSEKFCVDANQAGAGSWLKYIRVACS :. :. ..::: : ... . :::.::.: .:::::::: : XP_005 RSNLKDPSYGWE-----------------ILDEFYNVKFCIDASQPDVGSWLKYIRFAGC 120 130 140 150 180 190 200 210 220 230 pF1KA1 CDDQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDE :..::. :::..::.:.:. :: ::::::. .: :: :. : . :: .::..::. XP_005 YDQHNLVACQINDQIFYRVVADIAPGEELLLFMKSEDYPHETMAPDIHEERQYRCEDCDQ 160 170 180 190 200 210 240 250 260 270 280 290 pF1KA1 LFQSKLDLRRHKKYTCGSVGAALY---EGLAEELKPEGLGGGSGQAHECKDCERMFPNKY ::.:: .: :.:. :.. .:. : . ..:. :. .:::.:...::. XP_005 LFESKAELADHQKFPCSTPHSAFSMVEEDFQQKLESENDLQEIHTIQECKECDQVFPDLQ 220 230 240 250 260 270 300 310 320 330 340 350 pF1KA1 SLEQHMVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQR :::.::. :::::::::::::::::::::::::::::::::..:::::.::::::::::: XP_005 SLEKHMLSHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKHYECENCAKVFTDPSNLQR 280 290 300 310 320 330 360 370 380 390 400 410 pF1KA1 HIRSQHVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKR :::::::::::::::.:::::::::::::::::::.:::::::::::::::::::::::: XP_005 HIRSQHVGARAHACPECGKTFATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKR 340 350 360 370 380 390 420 430 440 450 460 470 pF1KA1 MHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKP ::::::::::::::::::::::::::::::::::::.. ::.:. :. : .: :::.. XP_005 MHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSM 400 410 420 430 440 450 480 490 500 510 520 530 pF1KA1 SPSLNHASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTPL ...::. :. .:: . ::..: : :: :... .:::.:: .:: ::::.: . XP_005 V-NMSHANPGLADYFGANRHPAGLTF----PTAPGFSFSFPGLFPSGLYHRPPLIPASSP 460 470 480 490 500 510 540 550 560 570 580 590 pF1KA1 LKSPLNHTQDAKLPSPL-GNPA-LPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLK .:. . : : ::: .: :: .. . .. . ..: .. : . : : :. XP_005 VKGLSSTEQTNKSQSPLMTHPQILPATQDILKA-LSKHPSVGDNKPVELQPERSSEERPF 520 530 540 550 560 570 600 610 620 630 640 650 pF1KA1 TRSSDMSDGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGG . ::.:..::..::.: .:.::.::.: :::.::..:: .: : .:: : XP_005 EKISDQSESSDLDDVSTPSGSDLETTSG--SDLESDIESDKEKFKENGK------MFKDK 580 590 600 610 620 660 670 680 690 700 710 pF1KA1 LAPPGAPNSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGP-GFMGM ..: :. . ::.::.: : :. ...::..::::::::::::::: :..:. XP_005 VSPLQNLASINNKKE-YSNHSIFSPSLEEQTAVSGAVNDSIKAIASIAEKYFGSTGLVGL 630 640 650 660 670 680 720 730 740 750 760 770 pF1KA1 QEKKLGSLPYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAEC :.::.:.::: : ::. :.: : .:.::: :: : ..: .: ::.:: .. :. :.: XP_005 QDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDL-RSLPLKMEPQSPGEVKKLQKGSSES 690 700 710 720 730 740 780 790 800 810 820 830 pF1KA1 PFDLTTKPKDVKPILPMP-KGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGE ::::::: :: ::. :.: : : .::....::::::.:::.::: . :::::::.: XP_005 PFDLTTKRKDEKPLTPVPSKPPVTPATSQDQPLDLSMGSRSRASGTKL-TEPRKNHVFGG 750 760 770 780 790 840 850 860 870 880 890 pF1KA1 RKLGAGEGLPQVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPS .: . :. : .. :..:.:.:::::::: ::::::.:::. :::::::::: XP_005 KKGSNVESRP-------ASDGSLQHARPTPFFMDPIY-RVEKRKLTDPLEALKEKYLRPS 800 810 820 830 840 850 900 910 920 930 940 pF1KA1 P-LLFHPQMSAIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKE : .::::::::::.:.::::::.:.: ... :: .: ::::.:: .: . .:::::: XP_005 PGFLFHPQMSAIENMAEKLESFSALKPEASELLQSVPSM-FNFRAPPNALPENLLRKGKE 860 870 880 890 900 910 950 960 970 980 990 1000 pF1KA1 RYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFK 920 930 940 950 960 970 1010 1020 1030 1040 1050 1060 pF1KA1 CHLCNRCFGQQTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNH-ALLDEK ::::.:::::::::::::::::. : ::..::: :: .. :.::.: XP_005 CHLCDRCFGQQTNLDRHLKKHENGNMS------------GTATSSPHSELESTGAILDDK 980 990 1000 1010 1070 1080 1090 1100 1110 1120 pF1KA1 EDSYFSEIRNFIANSEMNQASTRT-EKRAD-MQIVDGSAQCPGLASEKQEDVEEEDDDDL ::.::.::::::.::. .. : :. :.: . .. : .: . :. .: : ::. : XP_005 EDAYFTEIRNFIGNSNHGSQSPRNVEERMNGSHFKDEKALVTSQNSDLLDDEEVEDEVLL 1020 1030 1040 1050 1060 1070 1130 1140 1150 1160 1170 1180 pF1KA1 EEDDEDS-LAGKSQDDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLA .:.:::. ..::. . :. . .. ::. .: : .. . .: :....:: : XP_005 DEEDEDNDITGKTGKEPVT-SNLHEGNPEDDYEETSALEMSCKTSPVRYKEEEYKSGLSA 1080 1090 1100 1110 1120 1130 1190 1200 1210 1220 1230 1240 pF1KA1 LEPMPTFGKGLDLRRAAEEAFEVKDV--LNSTLDSEALKHTLCRQAKNQAYAMMLSLSED :. . : .: .:. .. . .. .... : ::. : :..:.::::::::::. XP_005 LDHIRHFTDSLKMRKMEDNQYSEAELSSFSTSHVPEELKQPLHRKSKSQAYAMMLSLSDK 1140 1150 1160 1170 1180 1190 1250 1260 1270 pF1KA1 TPLHTPSQGSLDAWLKVTGATSESGAFHPINHL ::. :..: ..: ... :..::.:.. :.:. XP_005 ESLHSTSHSSSNVWHSMARAAAESSAIQSISHV 1200 1210 1220 1230 >>XP_005247271 (OMIM: 165215,616738) PREDICTED: MDS1 and (1231 aa) initn: 3060 init1: 834 opt: 2055 Z-score: 879.8 bits: 175.0 E(85289): 2.9e-42 Smith-Waterman score: 4247; 52.6% identity (74.2% similar) in 1294 aa overlap (1-1276:1-1231) 10 20 30 40 50 pF1KA1 MRSKARARKLAKSDGDVVNNMYE-PNRDLLASHSAEDEAEDSAMSP-IPVGPP-SPFPTS ::::.:::::: .. : .:. : : ... .:. : .: . . : :: .: XP_005 MRSKGRARKLATNNECVYGNYPEIPLEEM-------PDADGVASTPSLNIQEPCSPATSS 10 20 30 40 50 60 70 80 90 100 110 pF1KA1 EDFTPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVP : :::::::::.::.:::.::::::.::::::..::::::.:.:::.:.::..:: : XP_005 EAFTPKEGSPYKAPIYIPDDIPIPAEFELRESNMPGAGLGIWTKRKIEVGEKFGPYVGEQ 60 70 80 90 100 110 120 130 140 150 160 170 pF1KA1 RAAAKETDFGWEQILTDVEVSPQEGCITKISEDLGSEKFCVDANQAGAGSWLKYIRVACS :. :. ..::: : ... . :::.::.: .:::::::: : XP_005 RSNLKDPSYGWE-----------------ILDEFYNVKFCIDASQPDVGSWLKYIRFAGC 120 130 140 150 180 190 200 210 220 230 pF1KA1 CDDQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDE :..::. :::..::.:.:. :: ::::::. .: :: :. : . :: .::..::. XP_005 YDQHNLVACQINDQIFYRVVADIAPGEELLLFMKSEDYPHETMAPDIHEERQYRCEDCDQ 160 170 180 190 200 210 240 250 260 270 280 290 pF1KA1 LFQSKLDLRRHKKYTCGSVGAALY---EGLAEELKPEGLGGGSGQAHECKDCERMFPNKY ::.:: .: :.:. :.. .:. : . ..:. :. .:::.:...::. XP_005 LFESKAELADHQKFPCSTPHSAFSMVEEDFQQKLESENDLQEIHTIQECKECDQVFPDLQ 220 230 240 250 260 270 300 310 320 330 340 350 pF1KA1 SLEQHMVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVK-VFTDPSNLQ :::.::. :::::::::::::::::::::::::::::::::..:::::.: ::::::::: XP_005 SLEKHMLSHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKHYECENCAKQVFTDPSNLQ 280 290 300 310 320 330 360 370 380 390 400 410 pF1KA1 RHIRSQHVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHK ::::::::::::::::.:::::::::::::::::::.::::::::::::::::::::::: XP_005 RHIRSQHVGARAHACPECGKTFATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHK 340 350 360 370 380 390 420 430 440 450 460 470 pF1KA1 RMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAK :::::::::::::::::::::::::::::::::::::.. ::.:. :. : .: :::.. XP_005 RMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTS 400 410 420 430 440 450 480 490 500 510 520 530 pF1KA1 PSPSLNHASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTP ...::. :. .:: . ::..: : :: :... .:::.:: .:: ::::.: . XP_005 MV-NMSHANPGLADYFGANRHPAGLTF----PTAPGFSFSFPGLFPSGLYHRPPLIPASS 460 470 480 490 500 510 540 550 560 570 580 590 pF1KA1 LLKSPLNHTQDAKLPSPL-GNPA-LPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKL .:. . : : ::: .: :: .. . .. . ..: .. : . : : :. XP_005 PVKGLSSTEQTNKSQSPLMTHPQILPATQDILKA-LSKHPSVGDNKPVELQPERSSEERP 520 530 540 550 560 570 600 610 620 630 640 650 pF1KA1 KTRSSDMSDGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGG . ::.:..::..::.: .:.::.::.: :::.::..:: .: : .:: : XP_005 FEKISDQSESSDLDDVSTPSGSDLETTSG--SDLESDIESDKEKFKENGK------MFKD 580 590 600 610 620 660 670 680 690 700 710 pF1KA1 GLAPPGAPNSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGP-GFMG ..: :. . ::.::.: : :. ...::..::::::::::::::: :..: XP_005 KVSPLQNLASINNKKE-YSNHSIFSPSLEEQTAVSGAVNDSIKAIASIAEKYFGSTGLVG 630 640 650 660 670 680 720 730 740 750 760 770 pF1KA1 MQEKKLGSLPYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAE .:.::.:.::: : ::. :.: : .:.::: :: : ..: .: ::.:: .. :. :.: XP_005 LQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDL-RSLPLKMEPQSPGEVKKLQKGSSE 690 700 710 720 730 740 780 790 800 810 820 pF1KA1 CPFDLTTKPKDVKPILPMP-KGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYG ::::::: :: ::. :.: : : .::....::::::.:::.::: . :::::::.: XP_005 SPFDLTTKRKDEKPLTPVPSKPPVTPATSQDQPLDLSMGSRSRASGTKL-TEPRKNHVFG 750 760 770 780 790 830 840 850 860 870 880 pF1KA1 ERKLGAGEGLPQVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRP .: . :. : .. :..:.:.:::::::: ::::::.:::. ::::::::: XP_005 GKKGSNVESRP-------ASDGSLQHARPTPFFMDPIY-RVEKRKLTDPLEALKEKYLRP 800 810 820 830 840 850 890 900 910 920 930 940 pF1KA1 SP-LLFHPQMSAIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGK :: .::::::::::.:.::::::.:.: ... :: .: ::::.:: .: . .::::: XP_005 SPGFLFHPQMSAIENMAEKLESFSALKPEASELLQSVPSM-FNFRAPPNALPENLLRKGK 860 870 880 890 900 910 950 960 970 980 990 1000 pF1KA1 ERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPF 920 930 940 950 960 970 1010 1020 1030 1040 1050 1060 pF1KA1 KCHLCNRCFGQQTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNH-ALLDE :::::.:::::::::::::::::. : ::..::: :: .. :.::. XP_005 KCHLCDRCFGQQTNLDRHLKKHENGNMS------------GTATSSPHSELESTGAILDD 980 990 1000 1010 1070 1080 1090 1100 1110 1120 pF1KA1 KEDSYFSEIRNFIANSEMNQASTRT-EKRAD-MQIVDGSAQCPGLASEKQEDVEEEDDDD :::.::.::::::.::. .. : :. :.: . .. : .: . :. .: : ::. XP_005 KEDAYFTEIRNFIGNSNHGSQSPRNVEERMNGSHFKDEKALVTSQNSDLLDDEEVEDEVL 1020 1030 1040 1050 1060 1070 1130 1140 1150 1160 1170 1180 pF1KA1 LEEDDEDS-LAGKSQDDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLL :.:.:::. ..::. . :. . .. ::. .: : .. . .: :....:: XP_005 LDEEDEDNDITGKTGKEPVT-SNLHEGNPEDDYEETSALEMSCKTSPVRYKEEEYKSGLS 1080 1090 1100 1110 1120 1130 1190 1200 1210 1220 1230 1240 pF1KA1 ALEPMPTFGKGLDLRRAAEEAFEVKDV--LNSTLDSEALKHTLCRQAKNQAYAMMLSLSE ::. . : .: .:. .. . .. .... : ::. : :..:.::::::::::. XP_005 ALDHIRHFTDSLKMRKMEDNQYSEAELSSFSTSHVPEELKQPLHRKSKSQAYAMMLSLSD 1140 1150 1160 1170 1180 1190 1250 1260 1270 pF1KA1 DTPLHTPSQGSLDAWLKVTGATSESGAFHPINHL ::. :..: ..: ... :..::.:.. :.:. XP_005 KESLHSTSHSSSNVWHSMARAAAESSAIQSISHV 1200 1210 1220 1230 1276 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 11:18:43 2016 done: Thu Nov 3 11:18:46 2016 Total Scan time: 18.750 Total Display time: 0.750 Function used was FASTA [36.3.4 Apr, 2011]