Result of FASTA (omim) for pF1KA1675
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA1675, 1276 aa
  1>>>pF1KA1675 1276 - 1276 aa - 1276 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 12.3368+/-0.000476; mu= -8.4602+/- 0.030
 mean_var=575.3148+/-120.223, 0's: 0 Z-trim(121.8): 1379  B-trim: 0 in 0/61
 Lambda= 0.053471
 statistics sampled from 37257 (38985) to 37257 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.752), E-opt: 0.2 (0.457), width:  16
 Scan time: 18.750

The best scores are:                                      opt bits E(85289)
NP_071397 (OMIM: 605557,615373) PR domain zinc fin (1276) 8833 697.8 1.2e-199
XP_005244829 (OMIM: 605557,615373) PREDICTED: PR d (1277) 8821 696.9 2.2e-199
XP_016857539 (OMIM: 605557,615373) PREDICTED: PR d (1275) 8816 696.5 2.9e-199
XP_006710877 (OMIM: 605557,615373) PREDICTED: PR d (1276) 8804 695.6 5.5e-199
NP_955533 (OMIM: 605557,615373) PR domain zinc fin (1257) 8541 675.3  7e-193
XP_005244830 (OMIM: 605557,615373) PREDICTED: PR d (1258) 8529 674.4 1.3e-192
XP_005244831 (OMIM: 605557,615373) PREDICTED: PR d (1178) 8146 644.8  1e-183
XP_011540247 (OMIM: 605557,615373) PREDICTED: PR d (1092) 7573 600.6 1.9e-170
XP_005247272 (OMIM: 165215,616738) PREDICTED: MDS1 (1230) 2067 175.9 1.5e-42
XP_005247271 (OMIM: 165215,616738) PREDICTED: MDS1 (1231) 2055 175.0 2.9e-42
NP_004982 (OMIM: 165215,616738) MDS1 and EVI1 comp (1239) 1929 165.2 2.4e-39
XP_011510848 (OMIM: 165215,616738) PREDICTED: MDS1 (1124) 1927 165.0 2.6e-39
XP_016861363 (OMIM: 165215,616738) PREDICTED: MDS1 (1116) 1916 164.2 4.6e-39
NP_001098547 (OMIM: 165215,616738) MDS1 and EVI1 c (1116) 1916 164.2 4.6e-39
XP_005247270 (OMIM: 165215,616738) PREDICTED: MDS1 (1240) 1917 164.3 4.6e-39
XP_016861364 (OMIM: 165215,616738) PREDICTED: MDS1 (1042) 1824 157.1   6e-37
NP_001157472 (OMIM: 165215,616738) MDS1 and EVI1 c (1042) 1824 157.1   6e-37
XP_016861365 (OMIM: 165215,616738) PREDICTED: MDS1 (1043) 1812 156.1 1.1e-36
NP_001157471 (OMIM: 165215,616738) MDS1 and EVI1 c (1043) 1812 156.1 1.1e-36
XP_005247280 (OMIM: 165215,616738) PREDICTED: MDS1 (1051) 1686 146.4 9.6e-34
NP_005232 (OMIM: 165215,616738) MDS1 and EVI1 comp (1051) 1686 146.4 9.6e-34
NP_001192123 (OMIM: 165215,616738) MDS1 and EVI1 c (1051) 1686 146.4 9.6e-34
NP_001098548 (OMIM: 165215,616738) MDS1 and EVI1 c (1051) 1686 146.4 9.6e-34
XP_005247278 (OMIM: 165215,616738) PREDICTED: MDS1 (1052) 1674 145.5 1.8e-33
XP_005247277 (OMIM: 165215,616738) PREDICTED: MDS1 (1052) 1674 145.5 1.8e-33
XP_005247276 (OMIM: 165215,616738) PREDICTED: MDS1 (1052) 1674 145.5 1.8e-33
XP_016861367 (OMIM: 165215,616738) PREDICTED: MDS1 ( 718) 1355 120.7 3.6e-26
XP_005247283 (OMIM: 165215,616738) PREDICTED: MDS1 ( 906) 1355 120.8 4.2e-26
XP_016861366 (OMIM: 165215,616738) PREDICTED: MDS1 ( 907) 1355 120.8 4.3e-26
XP_005247281 (OMIM: 165215,616738) PREDICTED: MDS1 ( 916) 1325 118.5 2.1e-25
XP_005247282 (OMIM: 165215,616738) PREDICTED: MDS1 ( 915) 1128 103.3   8e-21
XP_016867181 (OMIM: 604756) PREDICTED: zinc finger ( 504)  573 60.2 4.2e-08
XP_016867184 (OMIM: 604756) PREDICTED: zinc finger ( 504)  573 60.2 4.2e-08
XP_016867185 (OMIM: 604756) PREDICTED: zinc finger ( 504)  573 60.2 4.2e-08
XP_016867180 (OMIM: 604756) PREDICTED: zinc finger ( 504)  573 60.2 4.2e-08
XP_016867182 (OMIM: 604756) PREDICTED: zinc finger ( 504)  573 60.2 4.2e-08
XP_016867179 (OMIM: 604756) PREDICTED: zinc finger ( 504)  573 60.2 4.2e-08
XP_016867178 (OMIM: 604756) PREDICTED: zinc finger ( 504)  573 60.2 4.2e-08
XP_016867183 (OMIM: 604756) PREDICTED: zinc finger ( 504)  573 60.2 4.2e-08
XP_016867186 (OMIM: 604756) PREDICTED: zinc finger ( 504)  573 60.2 4.2e-08
XP_016867187 (OMIM: 604756) PREDICTED: zinc finger ( 504)  573 60.2 4.2e-08
XP_011514048 (OMIM: 604756) PREDICTED: zinc finger ( 537)  573 60.2 4.3e-08
NP_066971 (OMIM: 604756) zinc finger protein 273 [ ( 569)  573 60.2 4.5e-08
XP_016867177 (OMIM: 604756) PREDICTED: zinc finger ( 569)  573 60.2 4.5e-08
XP_011513163 (OMIM: 602277) PREDICTED: zinc finger ( 675)  572 60.3 5.3e-08
NP_001305822 (OMIM: 602277) zinc finger protein 18 ( 675)  572 60.3 5.3e-08
NP_001305820 (OMIM: 602277) zinc finger protein 18 ( 751)  572 60.3 5.7e-08
NP_001305821 (OMIM: 602277) zinc finger protein 18 ( 751)  572 60.3 5.7e-08
NP_009080 (OMIM: 602277) zinc finger protein 184 i ( 751)  572 60.3 5.7e-08
XP_016884975 (OMIM: 300498,314998) PREDICTED: zinc ( 661)  566 59.8 7.2e-08


>>NP_071397 (OMIM: 605557,615373) PR domain zinc finger   (1276 aa)
 initn: 8833 init1: 8833 opt: 8833  Z-score: 3705.5  bits: 697.8 E(85289): 1.2e-199
Smith-Waterman score: 8833; 99.9% identity (99.9% similar) in 1276 aa overlap (1-1276:1-1276)

               10        20        30        40        50        60
pF1KA1 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 AKETDFGWEQILTDVEVSPQEGCITKISEDLGSEKFCVDANQAGAGSWLKYIRVACSCDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 AKETDFGWEQILTDVEVSPQEGCITKISEDLGSEKFCVDANQAGAGSWLKYIRVACSCDD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 QNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 QNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELFQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 SKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQHM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 SKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQHM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 VIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 VIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 VGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADCR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 VGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADCR
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 TQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 TQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLNH
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 ASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTPLLKSPLN
       :::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
NP_071 ASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTSLLKSPLN
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 HTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 HTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMSD
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA1 GSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAPN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 GSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAPN
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA1 SVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 SVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSLP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA1 YHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 YHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKPK
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA1 DVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 DVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGLP
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA1 QVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 QVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMSA
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA1 IETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 IETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKIF
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA1 PRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 PRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQQ
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA1 TNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 TNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNFI
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA1 ANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 ANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQD
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA1 DTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 DTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLRR
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA1 AAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 AAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLKV
             1210      1220      1230      1240      1250      1260

             1270      
pF1KA1 TGATSESGAFHPINHL
       ::::::::::::::::
NP_071 TGATSESGAFHPINHL
             1270      

>>XP_005244829 (OMIM: 605557,615373) PREDICTED: PR domai  (1277 aa)
 initn: 7840 init1: 7840 opt: 8821  Z-score: 3700.4  bits: 696.9 E(85289): 2.2e-199
Smith-Waterman score: 8821; 99.8% identity (99.8% similar) in 1277 aa overlap (1-1276:1-1277)

               10        20        30        40        50        60
pF1KA1 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA
               70        80        90       100       110       120

              130       140        150       160       170         
pF1KA1 AKETDFGWEQILTDVEVSPQEGCITK-ISEDLGSEKFCVDANQAGAGSWLKYIRVACSCD
       :::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::
XP_005 AKETDFGWEQILTDVEVSPQEGCITKQISEDLGSEKFCVDANQAGAGSWLKYIRVACSCD
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KA1 DQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELF
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KA1 QSKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQH
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KA1 MVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQ
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KA1 HVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADC
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KA1 RTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLN
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KA1 HASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTPLLKSPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
XP_005 HASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTSLLKSPL
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KA1 NHTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NHTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMS
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KA1 DGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAP
              610       620       630       640       650       660

     660       670       680       690       700       710         
pF1KA1 NSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSL
              670       680       690       700       710       720

     720       730       740       750       760       770         
pF1KA1 PYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKP
              730       740       750       760       770       780

     780       790       800       810       820       830         
pF1KA1 KDVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGL
              790       800       810       820       830       840

     840       850       860       870       880       890         
pF1KA1 PQVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMS
              850       860       870       880       890       900

     900       910       920       930       940       950         
pF1KA1 AIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKI
              910       920       930       940       950       960

     960       970       980       990      1000      1010         
pF1KA1 FPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQ
              970       980       990      1000      1010      1020

    1020      1030      1040      1050      1060      1070         
pF1KA1 QTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNF
             1030      1040      1050      1060      1070      1080

    1080      1090      1100      1110      1120      1130         
pF1KA1 IANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQ
             1090      1100      1110      1120      1130      1140

    1140      1150      1160      1170      1180      1190         
pF1KA1 DDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLR
             1150      1160      1170      1180      1190      1200

    1200      1210      1220      1230      1240      1250         
pF1KA1 RAAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RAAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLK
             1210      1220      1230      1240      1250      1260

    1260      1270      
pF1KA1 VTGATSESGAFHPINHL
       :::::::::::::::::
XP_005 VTGATSESGAFHPINHL
             1270       

>>XP_016857539 (OMIM: 605557,615373) PREDICTED: PR domai  (1275 aa)
 initn: 8814 init1: 6062 opt: 8816  Z-score: 3698.4  bits: 696.5 E(85289): 2.9e-199
Smith-Waterman score: 8816; 99.8% identity (99.8% similar) in 1276 aa overlap (1-1276:1-1275)

               10        20        30        40        50        60
pF1KA1 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 AKETDFGWEQILTDVEVSPQEGCITKISEDLGSEKFCVDANQAGAGSWLKYIRVACSCDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKETDFGWEQILTDVEVSPQEGCITKISEDLGSEKFCVDANQAGAGSWLKYIRVACSCDD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 QNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELFQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 SKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQHM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQHM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 VIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 VGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADCR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADCR
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 TQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLNH
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 ASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTPLLKSPLN
       :::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_016 ASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTSLLKSPLN
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 HTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMSD
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA1 GSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAPN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAPN
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA1 SVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSLP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA1 YHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKPK
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA1 DVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGLP
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA1 QVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMSA
       ::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_016 QVCPARMPQQPPLHYAKPSPFFMDPIY-RVEKRKVTDPVGALKEKYLRPSPLLFHPQMSA
              850       860        870       880       890         

              910       920       930       940       950       960
pF1KA1 IETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKIF
     900       910       920       930       940       950         

              970       980       990      1000      1010      1020
pF1KA1 PRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQQ
     960       970       980       990      1000      1010         

             1030      1040      1050      1060      1070      1080
pF1KA1 TNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNFI
    1020      1030      1040      1050      1060      1070         

             1090      1100      1110      1120      1130      1140
pF1KA1 ANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQD
    1080      1090      1100      1110      1120      1130         

             1150      1160      1170      1180      1190      1200
pF1KA1 DTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLRR
    1140      1150      1160      1170      1180      1190         

             1210      1220      1230      1240      1250      1260
pF1KA1 AAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLKV
    1200      1210      1220      1230      1240      1250         

             1270      
pF1KA1 TGATSESGAFHPINHL
       ::::::::::::::::
XP_016 TGATSESGAFHPINHL
    1260      1270     

>>XP_006710877 (OMIM: 605557,615373) PREDICTED: PR domai  (1276 aa)
 initn: 5069 init1: 5069 opt: 8804  Z-score: 3693.4  bits: 695.6 E(85289): 5.5e-199
Smith-Waterman score: 8804; 99.8% identity (99.8% similar) in 1277 aa overlap (1-1276:1-1276)

               10        20        30        40        50        60
pF1KA1 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA
               70        80        90       100       110       120

              130       140        150       160       170         
pF1KA1 AKETDFGWEQILTDVEVSPQEGCITK-ISEDLGSEKFCVDANQAGAGSWLKYIRVACSCD
       :::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::
XP_006 AKETDFGWEQILTDVEVSPQEGCITKQISEDLGSEKFCVDANQAGAGSWLKYIRVACSCD
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KA1 DQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELF
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KA1 QSKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQH
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KA1 MVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQ
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KA1 HVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADC
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KA1 RTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLN
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KA1 HASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTPLLKSPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
XP_006 HASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTSLLKSPL
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KA1 NHTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NHTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMS
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KA1 DGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAP
              610       620       630       640       650       660

     660       670       680       690       700       710         
pF1KA1 NSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSL
              670       680       690       700       710       720

     720       730       740       750       760       770         
pF1KA1 PYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKP
              730       740       750       760       770       780

     780       790       800       810       820       830         
pF1KA1 KDVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KDVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGL
              790       800       810       820       830       840

     840       850       860       870       880       890         
pF1KA1 PQVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMS
       :::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::
XP_006 PQVCPARMPQQPPLHYAKPSPFFMDPIY-RVEKRKVTDPVGALKEKYLRPSPLLFHPQMS
              850       860        870       880       890         

     900       910       920       930       940       950         
pF1KA1 AIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKI
     900       910       920       930       940       950         

     960       970       980       990      1000      1010         
pF1KA1 FPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQ
     960       970       980       990      1000      1010         

    1020      1030      1040      1050      1060      1070         
pF1KA1 QTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNF
    1020      1030      1040      1050      1060      1070         

    1080      1090      1100      1110      1120      1130         
pF1KA1 IANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQ
    1080      1090      1100      1110      1120      1130         

    1140      1150      1160      1170      1180      1190         
pF1KA1 DDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLR
    1140      1150      1160      1170      1180      1190         

    1200      1210      1220      1230      1240      1250         
pF1KA1 RAAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RAAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLK
    1200      1210      1220      1230      1240      1250         

    1260      1270      
pF1KA1 VTGATSESGAFHPINHL
       :::::::::::::::::
XP_006 VTGATSESGAFHPINHL
    1260      1270      

>>NP_955533 (OMIM: 605557,615373) PR domain zinc finger   (1257 aa)
 initn: 8541 init1: 8541 opt: 8541  Z-score: 3583.8  bits: 675.3 E(85289): 7e-193
Smith-Waterman score: 8662; 98.4% identity (98.4% similar) in 1276 aa overlap (1-1276:1-1257)

               10        20        30        40        50        60
pF1KA1 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 AKETDFGWEQILTDVEVSPQEGCITKISEDLGSEKFCVDANQAGAGSWLKYIRVACSCDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 AKETDFGWEQILTDVEVSPQEGCITKISEDLGSEKFCVDANQAGAGSWLKYIRVACSCDD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 QNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 QNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELFQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 SKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQHM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 SKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQHM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 VIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 VIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 VGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADCR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 VGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADCR
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 TQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 TQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLNH
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 ASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTPLLKSPLN
       :::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
NP_955 ASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTSLLKSPLN
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 HTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 HTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMSD
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA1 GSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAPN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 GSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAPN
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA1 SVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 SVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSLP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA1 YHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 YHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKPK
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA1 DVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 DVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGLP
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA1 QVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 QVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMSA
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA1 IETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 IETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKIF
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA1 PRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 PRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQQ
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA1 TNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 TNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNFI
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA1 ANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 ANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQD
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA1 DTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 DTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLRR
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA1 AAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLKV
       ::::::::::::::::::::::::::::::::                   :::::::::
NP_955 AAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQ-------------------GSLDAWLKV
             1210      1220      1230                         1240 

             1270      
pF1KA1 TGATSESGAFHPINHL
       ::::::::::::::::
NP_955 TGATSESGAFHPINHL
            1250       

>>XP_005244830 (OMIM: 605557,615373) PREDICTED: PR domai  (1258 aa)
 initn: 7548 init1: 7548 opt: 8529  Z-score: 3578.8  bits: 674.4 E(85289): 1.3e-192
Smith-Waterman score: 8650; 98.4% identity (98.4% similar) in 1277 aa overlap (1-1276:1-1258)

               10        20        30        40        50        60
pF1KA1 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA
               70        80        90       100       110       120

              130       140        150       160       170         
pF1KA1 AKETDFGWEQILTDVEVSPQEGCITK-ISEDLGSEKFCVDANQAGAGSWLKYIRVACSCD
       :::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::
XP_005 AKETDFGWEQILTDVEVSPQEGCITKQISEDLGSEKFCVDANQAGAGSWLKYIRVACSCD
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KA1 DQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELF
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KA1 QSKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQH
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KA1 MVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQ
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KA1 HVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADC
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KA1 RTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLN
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KA1 HASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTPLLKSPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
XP_005 HASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTSLLKSPL
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KA1 NHTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NHTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMS
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KA1 DGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAP
              610       620       630       640       650       660

     660       670       680       690       700       710         
pF1KA1 NSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSL
              670       680       690       700       710       720

     720       730       740       750       760       770         
pF1KA1 PYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKP
              730       740       750       760       770       780

     780       790       800       810       820       830         
pF1KA1 KDVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGL
              790       800       810       820       830       840

     840       850       860       870       880       890         
pF1KA1 PQVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMS
              850       860       870       880       890       900

     900       910       920       930       940       950         
pF1KA1 AIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKI
              910       920       930       940       950       960

     960       970       980       990      1000      1010         
pF1KA1 FPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQ
              970       980       990      1000      1010      1020

    1020      1030      1040      1050      1060      1070         
pF1KA1 QTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNF
             1030      1040      1050      1060      1070      1080

    1080      1090      1100      1110      1120      1130         
pF1KA1 IANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQ
             1090      1100      1110      1120      1130      1140

    1140      1150      1160      1170      1180      1190         
pF1KA1 DDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLR
             1150      1160      1170      1180      1190      1200

    1200      1210      1220      1230      1240      1250         
pF1KA1 RAAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLK
       :::::::::::::::::::::::::::::::::                   ::::::::
XP_005 RAAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQ-------------------GSLDAWLK
             1210      1220      1230                         1240 

    1260      1270      
pF1KA1 VTGATSESGAFHPINHL
       :::::::::::::::::
XP_005 VTGATSESGAFHPINHL
            1250        

>>XP_005244831 (OMIM: 605557,615373) PREDICTED: PR domai  (1178 aa)
 initn: 7165 init1: 7165 opt: 8146  Z-score: 3419.4  bits: 644.8 E(85289): 1e-183
Smith-Waterman score: 8146; 99.8% identity (99.8% similar) in 1175 aa overlap (1-1174:1-1175)

               10        20        30        40        50        60
pF1KA1 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRSKARARKLAKSDGDVVNNMYEPNRDLLASHSAEDEAEDSAMSPIPVGPPSPFPTSEDF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVPRAA
               70        80        90       100       110       120

              130       140        150       160       170         
pF1KA1 AKETDFGWEQILTDVEVSPQEGCITK-ISEDLGSEKFCVDANQAGAGSWLKYIRVACSCD
       :::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::
XP_005 AKETDFGWEQILTDVEVSPQEGCITKQISEDLGSEKFCVDANQAGAGSWLKYIRVACSCD
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KA1 DQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDELF
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KA1 QSKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLGGGSGQAHECKDCERMFPNKYSLEQH
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KA1 MVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQ
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KA1 HVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADC
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KA1 RTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKPSPSLN
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KA1 HASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTPLLKSPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
XP_005 HASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTSLLKSPL
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KA1 NHTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NHTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLKTRSSDMS
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KA1 DGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGGLAPPGAP
              610       620       630       640       650       660

     660       670       680       690       700       710         
pF1KA1 NSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPGFMGMQEKKLGSL
              670       680       690       700       710       720

     720       730       740       750       760       770         
pF1KA1 PYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKP
              730       740       750       760       770       780

     780       790       800       810       820       830         
pF1KA1 KDVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDVKPILPMPKGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKLGAGEGL
              790       800       810       820       830       840

     840       850       860       870       880       890         
pF1KA1 PQVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPSPLLFHPQMS
              850       860       870       880       890       900

     900       910       920       930       940       950         
pF1KA1 AIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKI
              910       920       930       940       950       960

     960       970       980       990      1000      1010         
pF1KA1 FPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQ
              970       980       990      1000      1010      1020

    1020      1030      1040      1050      1060      1070         
pF1KA1 QTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNF
             1030      1040      1050      1060      1070      1080

    1080      1090      1100      1110      1120      1130         
pF1KA1 IANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQ
             1090      1100      1110      1120      1130      1140

    1140      1150      1160      1170      1180      1190         
pF1KA1 DDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLALEPMPTFGKGLDLR
       :::::::::::::::::::::::::::::::::::                         
XP_005 DDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRHMQ                      
             1150      1160      1170                              

    1200      1210      1220      1230      1240      1250         
pF1KA1 RAAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLSEDTPLHTPSQGSLDAWLK

>>XP_011540247 (OMIM: 605557,615373) PREDICTED: PR domai  (1092 aa)
 initn: 7573 init1: 7573 opt: 7573  Z-score: 3180.9  bits: 600.6 E(85289): 1.9e-170
Smith-Waterman score: 7573; 99.9% identity (99.9% similar) in 1092 aa overlap (185-1276:1-1092)

          160       170       180       190       200       210    
pF1KA1 KFCVDANQAGAGSWLKYIRVACSCDDQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGV
                                     ::::::::::::::::::::::::::::::
XP_011                               MCQISEQIYYKVIKDIEPGEELLVHVKEGV
                                             10        20        30

          220       230       240       250       260       270    
pF1KA1 YPLGTVPPGLDEEPTFRCDECDELFQSKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPLGTVPPGLDEEPTFRCDECDELFQSKLDLRRHKKYTCGSVGAALYEGLAEELKPEGLG
               40        50        60        70        80        90

          280       290       300       310       320       330    
pF1KA1 GGSGQAHECKDCERMFPNKYSLEQHMVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGSGQAHECKDCERMFPNKYSLEQHMVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSG
              100       110       120       130       140       150

          340       350       360       370       380       390    
pF1KA1 KRFECENCVKVFTDPSNLQRHIRSQHVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRFECENCVKVFTDPSNLQRHIRSQHVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPF
              160       170       180       190       200       210

          400       410       420       430       440       450    
pF1KA1 ICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPG
              220       230       240       250       260       270

          460       470       480       490       500       510    
pF1KA1 GIFAPGLPLTPSPMMDKAKPSPSLNHASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIFAPGLPLTPSPMMDKAKPSPSLNHASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGF
              280       290       300       310       320       330

          520       530       540       550       560       570    
pF1KA1 PGIFPPSLYPRPPLLPPTPLLKSPLNHTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAG
       :::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_011 PGIFPPSLYPRPPLLPPTSLLKSPLNHTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAG
              340       350       360       370       380       390

          580       590       600       610       620       630    
pF1KA1 PEEKFESRLEDSCVEKLKTRSSDMSDGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEEKFESRLEDSCVEKLKTRSSDMSDGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPD
              400       410       420       430       440       450

          640       650       660       670       680       690    
pF1KA1 KDKGKGKSAEGQPKFGGGLAPPGAPNSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDKGKGKSAEGQPKFGGGLAPPGAPNSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIK
              460       470       480       490       500       510

          700       710       720       730       740       750    
pF1KA1 AIASIAEKYFGPGFMGMQEKKLGSLPYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIASIAEKYFGPGFMGMQEKKLGSLPYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAE
              520       530       540       550       560       570

          760       770       780       790       800       810    
pF1KA1 PKSPRDALKVGGPSAECPFDLTTKPKDVKPILPMPKGPSAPASGEEQPLDLSIGSRARAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKSPRDALKVGGPSAECPFDLTTKPKDVKPILPMPKGPSAPASGEEQPLDLSIGSRARAS
              580       590       600       610       620       630

          820       830       840       850       860       870    
pF1KA1 QNGGGREPRKNHVYGERKLGAGEGLPQVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNGGGREPRKNHVYGERKLGAGEGLPQVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRK
              640       650       660       670       680       690

          880       890       900       910       920       930    
pF1KA1 VTDPVGALKEKYLRPSPLLFHPQMSAIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTDPVGALKEKYLRPSPLLFHPQMSAIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRS
              700       710       720       730       740       750

          940       950       960       970       980       990    
pF1KA1 PPPTLSDPILRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPTLSDPILRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNL
              760       770       780       790       800       810

         1000      1010      1020      1030      1040      1050    
pF1KA1 QRHVRNIHNKEKPFKCHLCNRCFGQQTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRHVRNIHNKEKPFKCHLCNRCFGQQTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASS
              820       830       840       850       860       870

         1060      1070      1080      1090      1100      1110    
pF1KA1 PTSESDNHALLDEKEDSYFSEIRNFIANSEMNQASTRTEKRADMQIVDGSAQCPGLASEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTSESDNHALLDEKEDSYFSEIRNFIANSEMNQASTRTEKRADMQIVDGSAQCPGLASEK
              880       890       900       910       920       930

         1120      1130      1140      1150      1160      1170    
pF1KA1 QEDVEEEDDDDLEEDDEDSLAGKSQDDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEDVEEEDDDDLEEDDEDSLAGKSQDDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRR
              940       950       960       970       980       990

         1180      1190      1200      1210      1220      1230    
pF1KA1 CAEDHEGGLLALEPMPTFGKGLDLRRAAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAEDHEGGLLALEPMPTFGKGLDLRRAAEEAFEVKDVLNSTLDSEALKHTLCRQAKNQAY
             1000      1010      1020      1030      1040      1050

         1240      1250      1260      1270      
pF1KA1 AMMLSLSEDTPLHTPSQGSLDAWLKVTGATSESGAFHPINHL
       ::::::::::::::::::::::::::::::::::::::::::
XP_011 AMMLSLSEDTPLHTPSQGSLDAWLKVTGATSESGAFHPINHL
             1060      1070      1080      1090  

>>XP_005247272 (OMIM: 165215,616738) PREDICTED: MDS1 and  (1230 aa)
 initn: 3393 init1: 1228 opt: 2067  Z-score: 884.8  bits: 175.9 E(85289): 1.5e-42
Smith-Waterman score: 4259; 52.6% identity (74.2% similar) in 1293 aa overlap (1-1276:1-1230)

               10        20         30        40         50        
pF1KA1 MRSKARARKLAKSDGDVVNNMYE-PNRDLLASHSAEDEAEDSAMSP-IPVGPP-SPFPTS
       ::::.:::::: ..  : .:. : : ...        .:.  : .: . .  : ::  .:
XP_005 MRSKGRARKLATNNECVYGNYPEIPLEEM-------PDADGVASTPSLNIQEPCSPATSS
               10        20               30        40        50   

        60        70        80        90       100       110       
pF1KA1 EDFTPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVP
       : :::::::::.::.:::.::::::.::::::..::::::.:.:::.:.::..:: :   
XP_005 EAFTPKEGSPYKAPIYIPDDIPIPAEFELRESNMPGAGLGIWTKRKIEVGEKFGPYVGEQ
            60        70        80        90       100       110   

       120       130       140       150       160       170       
pF1KA1 RAAAKETDFGWEQILTDVEVSPQEGCITKISEDLGSEKFCVDANQAGAGSWLKYIRVACS
       :.  :. ..:::                 : ... . :::.::.:  .:::::::: :  
XP_005 RSNLKDPSYGWE-----------------ILDEFYNVKFCIDASQPDVGSWLKYIRFAGC
           120                        130       140       150      

       180       190       200       210       220       230       
pF1KA1 CDDQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDE
        :..::. :::..::.:.:. :: ::::::. .:   ::  :. : . ::  .::..::.
XP_005 YDQHNLVACQINDQIFYRVVADIAPGEELLLFMKSEDYPHETMAPDIHEERQYRCEDCDQ
        160       170       180       190       200       210      

       240       250       260          270       280       290    
pF1KA1 LFQSKLDLRRHKKYTCGSVGAALY---EGLAEELKPEGLGGGSGQAHECKDCERMFPNKY
       ::.:: .:  :.:. :..  .:.    : . ..:. :.        .:::.:...::.  
XP_005 LFESKAELADHQKFPCSTPHSAFSMVEEDFQQKLESENDLQEIHTIQECKECDQVFPDLQ
        220       230       240       250       260       270      

          300       310       320       330       340       350    
pF1KA1 SLEQHMVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQR
       :::.::. :::::::::::::::::::::::::::::::::..:::::.:::::::::::
XP_005 SLEKHMLSHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKHYECENCAKVFTDPSNLQR
        280       290       300       310       320       330      

          360       370       380       390       400       410    
pF1KA1 HIRSQHVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKR
       :::::::::::::::.:::::::::::::::::::.::::::::::::::::::::::::
XP_005 HIRSQHVGARAHACPECGKTFATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKR
        340       350       360       370       380       390      

          420       430       440       450       460       470    
pF1KA1 MHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAKP
       ::::::::::::::::::::::::::::::::::::.. ::.:. :. :  .: :::.. 
XP_005 MHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSM
        400       410       420       430       440       450      

          480       490       500       510       520       530    
pF1KA1 SPSLNHASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTPL
         ...::. :. .:: .  ::..: :    :: :... .:::.:: .:: ::::.: .  
XP_005 V-NMSHANPGLADYFGANRHPAGLTF----PTAPGFSFSFPGLFPSGLYHRPPLIPASSP
         460       470       480           490       500       510 

          540       550         560       570       580       590  
pF1KA1 LKSPLNHTQDAKLPSPL-GNPA-LPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLK
       .:.  .  :  :  :::  .:  :: .. . ..  .   ..: ..  : . : :  :.  
XP_005 VKGLSSTEQTNKSQSPLMTHPQILPATQDILKA-LSKHPSVGDNKPVELQPERSSEERPF
             520       530       540        550       560       570

            600       610       620       630       640       650  
pF1KA1 TRSSDMSDGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGGG
        . ::.:..::..::.: .:.::.::.:  :::.::..:: .: : .::       :   
XP_005 EKISDQSESSDLDDVSTPSGSDLETTSG--SDLESDIESDKEKFKENGK------MFKDK
              580       590         600       610             620  

            660       670       680       690       700        710 
pF1KA1 LAPPGAPNSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGP-GFMGM
       ..:     :. .    ::.::.: :  :.  ...::..:::::::::::::::  :..:.
XP_005 VSPLQNLASINNKKE-YSNHSIFSPSLEEQTAVSGAVNDSIKAIASIAEKYFGSTGLVGL
            630        640       650       660       670       680 

             720       730       740       750       760       770 
pF1KA1 QEKKLGSLPYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAEC
       :.::.:.::: : ::. :.: : .:.::: :: : ..: .: ::.:: .. :.   :.: 
XP_005 QDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDL-RSLPLKMEPQSPGEVKKLQKGSSES
             690       700       710        720       730       740

             780        790       800       810       820       830
pF1KA1 PFDLTTKPKDVKPILPMP-KGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYGE
       ::::::: :: ::. :.: : : .::....::::::.:::.::: .    :::::::.: 
XP_005 PFDLTTKRKDEKPLTPVPSKPPVTPATSQDQPLDLSMGSRSRASGTKL-TEPRKNHVFGG
              750       760       770       780        790         

              840       850       860       870       880       890
pF1KA1 RKLGAGEGLPQVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRPS
       .: .  :. :        ..  :..:.:.:::::::: ::::::.:::. ::::::::::
XP_005 KKGSNVESRP-------ASDGSLQHARPTPFFMDPIY-RVEKRKLTDPLEALKEKYLRPS
     800              810       820        830       840       850 

               900       910       920       930       940         
pF1KA1 P-LLFHPQMSAIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKE
       : .::::::::::.:.::::::.:.: ...  :: .:   ::::.:: .: . .::::::
XP_005 PGFLFHPQMSAIENMAEKLESFSALKPEASELLQSVPSM-FNFRAPPNALPENLLRKGKE
             860       870       880       890        900       910

     950       960       970       980       990      1000         
pF1KA1 RYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFK
              920       930       940       950       960       970

    1010      1020      1030      1040      1050      1060         
pF1KA1 CHLCNRCFGQQTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNH-ALLDEK
       ::::.:::::::::::::::::. :              ::..::: :: ..  :.::.:
XP_005 CHLCDRCFGQQTNLDRHLKKHENGNMS------------GTATSSPHSELESTGAILDDK
              980       990                  1000      1010        

     1070      1080      1090        1100      1110      1120      
pF1KA1 EDSYFSEIRNFIANSEMNQASTRT-EKRAD-MQIVDGSAQCPGLASEKQEDVEEEDDDDL
       ::.::.::::::.::. .. : :. :.: .  .. : .:   .  :.  .: : ::.  :
XP_005 EDAYFTEIRNFIGNSNHGSQSPRNVEERMNGSHFKDEKALVTSQNSDLLDDEEVEDEVLL
     1020      1030      1040      1050      1060      1070        

       1130       1140      1150      1160      1170      1180     
pF1KA1 EEDDEDS-LAGKSQDDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLLA
       .:.:::. ..::.  . :. .   ..  ::. .:  :  ..   . .:   :....:: :
XP_005 DEEDEDNDITGKTGKEPVT-SNLHEGNPEDDYEETSALEMSCKTSPVRYKEEEYKSGLSA
     1080      1090       1100      1110      1120      1130       

        1190      1200      1210        1220      1230      1240   
pF1KA1 LEPMPTFGKGLDLRRAAEEAFEVKDV--LNSTLDSEALKHTLCRQAKNQAYAMMLSLSED
       :. .  :  .: .:.  .. .   ..  ....   : ::. : :..:.::::::::::. 
XP_005 LDHIRHFTDSLKMRKMEDNQYSEAELSSFSTSHVPEELKQPLHRKSKSQAYAMMLSLSDK
      1140      1150      1160      1170      1180      1190       

          1250      1260      1270      
pF1KA1 TPLHTPSQGSLDAWLKVTGATSESGAFHPINHL
         ::. :..: ..: ... :..::.:.. :.:.
XP_005 ESLHSTSHSSSNVWHSMARAAAESSAIQSISHV
      1200      1210      1220      1230

>>XP_005247271 (OMIM: 165215,616738) PREDICTED: MDS1 and  (1231 aa)
 initn: 3060 init1: 834 opt: 2055  Z-score: 879.8  bits: 175.0 E(85289): 2.9e-42
Smith-Waterman score: 4247; 52.6% identity (74.2% similar) in 1294 aa overlap (1-1276:1-1231)

               10        20         30        40         50        
pF1KA1 MRSKARARKLAKSDGDVVNNMYE-PNRDLLASHSAEDEAEDSAMSP-IPVGPP-SPFPTS
       ::::.:::::: ..  : .:. : : ...        .:.  : .: . .  : ::  .:
XP_005 MRSKGRARKLATNNECVYGNYPEIPLEEM-------PDADGVASTPSLNIQEPCSPATSS
               10        20               30        40        50   

        60        70        80        90       100       110       
pF1KA1 EDFTPKEGSPYEAPVYIPEDIPIPADFELRESSIPGAGLGVWAKRKMEAGERLGPCVVVP
       : :::::::::.::.:::.::::::.::::::..::::::.:.:::.:.::..:: :   
XP_005 EAFTPKEGSPYKAPIYIPDDIPIPAEFELRESNMPGAGLGIWTKRKIEVGEKFGPYVGEQ
            60        70        80        90       100       110   

       120       130       140       150       160       170       
pF1KA1 RAAAKETDFGWEQILTDVEVSPQEGCITKISEDLGSEKFCVDANQAGAGSWLKYIRVACS
       :.  :. ..:::                 : ... . :::.::.:  .:::::::: :  
XP_005 RSNLKDPSYGWE-----------------ILDEFYNVKFCIDASQPDVGSWLKYIRFAGC
           120                        130       140       150      

       180       190       200       210       220       230       
pF1KA1 CDDQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPGLDEEPTFRCDECDE
        :..::. :::..::.:.:. :: ::::::. .:   ::  :. : . ::  .::..::.
XP_005 YDQHNLVACQINDQIFYRVVADIAPGEELLLFMKSEDYPHETMAPDIHEERQYRCEDCDQ
        160       170       180       190       200       210      

       240       250       260          270       280       290    
pF1KA1 LFQSKLDLRRHKKYTCGSVGAALY---EGLAEELKPEGLGGGSGQAHECKDCERMFPNKY
       ::.:: .:  :.:. :..  .:.    : . ..:. :.        .:::.:...::.  
XP_005 LFESKAELADHQKFPCSTPHSAFSMVEEDFQQKLESENDLQEIHTIQECKECDQVFPDLQ
        220       230       240       250       260       270      

          300       310       320       330       340        350   
pF1KA1 SLEQHMVIHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVK-VFTDPSNLQ
       :::.::. :::::::::::::::::::::::::::::::::..:::::.: :::::::::
XP_005 SLEKHMLSHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKHYECENCAKQVFTDPSNLQ
        280       290       300       310       320       330      

           360       370       380       390       400       410   
pF1KA1 RHIRSQHVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHK
       ::::::::::::::::.:::::::::::::::::::.:::::::::::::::::::::::
XP_005 RHIRSQHVGARAHACPECGKTFATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHK
        340       350       360       370       380       390      

           420       430       440       450       460       470   
pF1KA1 RMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAK
       :::::::::::::::::::::::::::::::::::::.. ::.:. :. :  .: :::..
XP_005 RMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTS
        400       410       420       430       440       450      

           480       490       500       510       520       530   
pF1KA1 PSPSLNHASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTP
          ...::. :. .:: .  ::..: :    :: :... .:::.:: .:: ::::.: . 
XP_005 MV-NMSHANPGLADYFGANRHPAGLTF----PTAPGFSFSFPGLFPSGLYHRPPLIPASS
         460       470       480           490       500       510 

           540       550         560       570       580       590 
pF1KA1 LLKSPLNHTQDAKLPSPL-GNPA-LPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKL
        .:.  .  :  :  :::  .:  :: .. . ..  .   ..: ..  : . : :  :. 
XP_005 PVKGLSSTEQTNKSQSPLMTHPQILPATQDILKA-LSKHPSVGDNKPVELQPERSSEERP
             520       530       540        550       560       570

             600       610       620       630       640       650 
pF1KA1 KTRSSDMSDGSDFEDVNTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKGKSAEGQPKFGG
         . ::.:..::..::.: .:.::.::.:  :::.::..:: .: : .::       :  
XP_005 FEKISDQSESSDLDDVSTPSGSDLETTSG--SDLESDIESDKEKFKENGK------MFKD
              580       590         600       610             620  

             660       670       680       690       700        710
pF1KA1 GLAPPGAPNSVAEVPVFYSQHSFFPPPDEQLLTATGAAGDSIKAIASIAEKYFGP-GFMG
        ..:     :. .    ::.::.: :  :.  ...::..:::::::::::::::  :..:
XP_005 KVSPLQNLASINNKKE-YSNHSIFSPSLEEQTAVSGAVNDSIKAIASIAEKYFGSTGLVG
            630        640       650       660       670       680 

              720       730       740       750       760       770
pF1KA1 MQEKKLGSLPYHSAFPFQFLPNFPHSLYPFTDRALAHNLLVKAEPKSPRDALKVGGPSAE
       .:.::.:.::: : ::. :.: : .:.::: :: : ..: .: ::.:: .. :.   :.:
XP_005 LQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDL-RSLPLKMEPQSPGEVKKLQKGSSE
             690       700       710        720       730       740

              780        790       800       810       820         
pF1KA1 CPFDLTTKPKDVKPILPMP-KGPSAPASGEEQPLDLSIGSRARASQNGGGREPRKNHVYG
        ::::::: :: ::. :.: : : .::....::::::.:::.::: .    :::::::.:
XP_005 SPFDLTTKRKDEKPLTPVPSKPPVTPATSQDQPLDLSMGSRSRASGTKL-TEPRKNHVFG
              750       760       770       780        790         

     830       840       850       860       870       880         
pF1KA1 ERKLGAGEGLPQVCPARMPQQPPLHYAKPSPFFMDPIYSRVEKRKVTDPVGALKEKYLRP
        .: .  :. :        ..  :..:.:.:::::::: ::::::.:::. :::::::::
XP_005 GKKGSNVESRP-------ASDGSLQHARPTPFFMDPIY-RVEKRKLTDPLEALKEKYLRP
     800       810              820       830        840       850 

     890        900       910       920       930       940        
pF1KA1 SP-LLFHPQMSAIETMTEKLESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGK
       :: .::::::::::.:.::::::.:.: ...  :: .:   ::::.:: .: . .:::::
XP_005 SPGFLFHPQMSAIENMAEKLESFSALKPEASELLQSVPSM-FNFRAPPNALPENLLRKGK
             860       870       880       890        900       910

      950       960       970       980       990      1000        
pF1KA1 ERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPF
              920       930       940       950       960       970

     1010      1020      1030      1040      1050      1060        
pF1KA1 KCHLCNRCFGQQTNLDRHLKKHEHENAPVSQHPGVLTNHLGTSASSPTSESDNH-ALLDE
       :::::.:::::::::::::::::. :              ::..::: :: ..  :.::.
XP_005 KCHLCDRCFGQQTNLDRHLKKHENGNMS------------GTATSSPHSELESTGAILDD
              980       990                  1000      1010        

      1070      1080      1090        1100      1110      1120     
pF1KA1 KEDSYFSEIRNFIANSEMNQASTRT-EKRAD-MQIVDGSAQCPGLASEKQEDVEEEDDDD
       :::.::.::::::.::. .. : :. :.: .  .. : .:   .  :.  .: : ::.  
XP_005 KEDAYFTEIRNFIGNSNHGSQSPRNVEERMNGSHFKDEKALVTSQNSDLLDDEEVEDEVL
     1020      1030      1040      1050      1060      1070        

        1130       1140      1150      1160      1170      1180    
pF1KA1 LEEDDEDS-LAGKSQDDTVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRRCAEDHEGGLL
       :.:.:::. ..::.  . :. .   ..  ::. .:  :  ..   . .:   :....:: 
XP_005 LDEEDEDNDITGKTGKEPVT-SNLHEGNPEDDYEETSALEMSCKTSPVRYKEEEYKSGLS
     1080      1090       1100      1110      1120      1130       

         1190      1200      1210        1220      1230      1240  
pF1KA1 ALEPMPTFGKGLDLRRAAEEAFEVKDV--LNSTLDSEALKHTLCRQAKNQAYAMMLSLSE
       ::. .  :  .: .:.  .. .   ..  ....   : ::. : :..:.::::::::::.
XP_005 ALDHIRHFTDSLKMRKMEDNQYSEAELSSFSTSHVPEELKQPLHRKSKSQAYAMMLSLSD
      1140      1150      1160      1170      1180      1190       

           1250      1260      1270      
pF1KA1 DTPLHTPSQGSLDAWLKVTGATSESGAFHPINHL
          ::. :..: ..: ... :..::.:.. :.:.
XP_005 KESLHSTSHSSSNVWHSMARAAAESSAIQSISHV
      1200      1210      1220      1230 




1276 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 11:18:43 2016 done: Thu Nov  3 11:18:46 2016
 Total Scan time: 18.750 Total Display time:  0.750

Function used was FASTA [36.3.4 Apr, 2011]
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