Result of FASTA (omim) for
pF1KA1682
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1682, 747 aa
1>>>pF1KA1682 747 - 747 aa - 747 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6892+/-0.000406; mu= 18.2391+/- 0.025
mean_var=75.8038+/-15.059, 0's: 0 Z-trim(113.0): 106 B-trim: 0 in 0/51
Lambda= 0.147309
statistics sampled from 22027 (22133) to 22027 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.63), E-opt: 0.2 (0.26), width: 16
Scan time: 11.340
The best scores are: opt bits E(85289)
NP_001035536 (OMIM: 606501) myotubularin-related p ( 747) 5097 1093.2 0
XP_005248370 (OMIM: 606501) PREDICTED: myotubulari ( 767) 3831 824.2 0
XP_016865084 (OMIM: 606501) PREDICTED: myotubulari ( 544) 3746 806.0 0
XP_016865083 (OMIM: 606501) PREDICTED: myotubulari ( 544) 3746 806.0 0
XP_016865082 (OMIM: 606501) PREDICTED: myotubulari ( 544) 3746 806.0 0
XP_011512360 (OMIM: 606501) PREDICTED: myotubulari ( 779) 3493 752.3 1.7e-216
NP_001281272 (OMIM: 606501) myotubularin-related p ( 693) 3459 745.1 2.2e-214
NP_001281273 (OMIM: 606501) myotubularin-related p ( 637) 3063 660.9 4.5e-189
XP_016865078 (OMIM: 606501) PREDICTED: myotubulari ( 691) 3063 660.9 4.8e-189
XP_011512361 (OMIM: 606501) PREDICTED: myotubulari ( 743) 2728 589.8 1.4e-167
XP_016865081 (OMIM: 606501) PREDICTED: myotubulari ( 564) 2480 537.0 8.1e-152
XP_016865079 (OMIM: 606501) PREDICTED: myotubulari ( 596) 2227 483.2 1.3e-135
XP_016865080 (OMIM: 606501) PREDICTED: myotubulari ( 596) 2227 483.2 1.3e-135
XP_011512359 (OMIM: 606501) PREDICTED: myotubulari ( 799) 2227 483.3 1.7e-135
XP_016865085 (OMIM: 606501) PREDICTED: myotubulari ( 488) 1712 373.7 9.7e-103
XP_011512362 (OMIM: 606501) PREDICTED: myotubulari ( 669) 1597 349.4 2.9e-95
XP_011542133 (OMIM: 606260) PREDICTED: myotubulari ( 353) 426 100.4 1.4e-20
XP_011542132 (OMIM: 606260) PREDICTED: myotubulari ( 442) 426 100.4 1.7e-20
NP_056273 (OMIM: 606260) myotubularin-related prot ( 549) 426 100.5 2e-20
XP_016885412 (OMIM: 300171) PREDICTED: myotubulari ( 552) 392 93.2 3e-18
NP_001230500 (OMIM: 601382,603557) myotubularin-re ( 571) 392 93.2 3.1e-18
XP_016885410 (OMIM: 300171) PREDICTED: myotubulari ( 571) 392 93.2 3.1e-18
XP_005274432 (OMIM: 601382,603557) PREDICTED: myot ( 571) 392 93.2 3.1e-18
XP_011529511 (OMIM: 300171) PREDICTED: myotubulari ( 571) 392 93.2 3.1e-18
XP_006718999 (OMIM: 601382,603557) PREDICTED: myot ( 571) 392 93.2 3.1e-18
XP_016874007 (OMIM: 601382,603557) PREDICTED: myot ( 571) 392 93.2 3.1e-18
XP_006718997 (OMIM: 601382,603557) PREDICTED: myot ( 571) 392 93.2 3.1e-18
XP_016874006 (OMIM: 601382,603557) PREDICTED: myot ( 571) 392 93.2 3.1e-18
XP_016885411 (OMIM: 300171) PREDICTED: myotubulari ( 571) 392 93.2 3.1e-18
NP_958435 (OMIM: 601382,603557) myotubularin-relat ( 571) 392 93.2 3.1e-18
XP_005274431 (OMIM: 601382,603557) PREDICTED: myot ( 571) 392 93.2 3.1e-18
XP_006718998 (OMIM: 601382,603557) PREDICTED: myot ( 571) 392 93.2 3.1e-18
NP_958438 (OMIM: 601382,603557) myotubularin-relat ( 571) 392 93.2 3.1e-18
XP_011541361 (OMIM: 601382,603557) PREDICTED: myot ( 596) 392 93.2 3.2e-18
XP_011541360 (OMIM: 601382,603557) PREDICTED: myot ( 596) 392 93.2 3.2e-18
NP_057240 (OMIM: 601382,603557) myotubularin-relat ( 643) 392 93.3 3.4e-18
XP_006724918 (OMIM: 300171) PREDICTED: myotubulari ( 665) 392 93.3 3.5e-18
NP_003819 (OMIM: 300171) myotubularin-related prot ( 665) 392 93.3 3.5e-18
NP_001293073 (OMIM: 300171) myotubularin-related p ( 673) 392 93.3 3.6e-18
XP_005274823 (OMIM: 300171) PREDICTED: myotubulari ( 682) 392 93.3 3.6e-18
XP_005274824 (OMIM: 300171) PREDICTED: myotubulari ( 682) 392 93.3 3.6e-18
XP_005274822 (OMIM: 300171) PREDICTED: myotubulari ( 699) 392 93.3 3.7e-18
XP_016885409 (OMIM: 300171) PREDICTED: myotubulari ( 602) 391 93.0 3.8e-18
XP_016885040 (OMIM: 300415,310400) PREDICTED: myot ( 355) 387 92.1 4.4e-18
XP_016885039 (OMIM: 300415,310400) PREDICTED: myot ( 566) 387 92.2 6.5e-18
XP_016885038 (OMIM: 300415,310400) PREDICTED: myot ( 602) 387 92.2 6.8e-18
XP_011529475 (OMIM: 300415,310400) PREDICTED: myot ( 603) 387 92.2 6.8e-18
NP_000243 (OMIM: 300415,310400) myotubularin [Homo ( 603) 387 92.2 6.8e-18
XP_005274744 (OMIM: 300415,310400) PREDICTED: myot ( 603) 387 92.2 6.8e-18
XP_016885036 (OMIM: 300415,310400) PREDICTED: myot ( 617) 387 92.2 6.9e-18
>>NP_001035536 (OMIM: 606501) myotubularin-related prote (747 aa)
initn: 5097 init1: 5097 opt: 5097 Z-score: 5850.6 bits: 1093.2 E(85289): 0
Smith-Waterman score: 5097; 100.0% identity (100.0% similar) in 747 aa overlap (1-747:1-747)
10 20 30 40 50 60
pF1KA1 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 AYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 YKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 SWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 SLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 SDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 YVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLIN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 SSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGQVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGQVAT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 LSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQRHSSKPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQRHSSKPVL
670 680 690 700 710 720
730 740
pF1KA1 PTSGWKALGDEDDLAKREDEFVDLGDV
:::::::::::::::::::::::::::
NP_001 PTSGWKALGDEDDLAKREDEFVDLGDV
730 740
>>XP_005248370 (OMIM: 606501) PREDICTED: myotubularin-re (767 aa)
initn: 5083 init1: 3828 opt: 3831 Z-score: 4396.3 bits: 824.2 E(85289): 0
Smith-Waterman score: 5047; 97.4% identity (97.4% similar) in 767 aa overlap (1-747:1-767)
10 20 30 40 50 60
pF1KA1 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 AYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 YKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 SWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 SLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 SDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPL
490 500 510 520 530 540
550 560 570 580
pF1KA1 YVEKPKLDKGQRKGMRFK--------------------HQRQLSLPLTQSKSSPKRGFFR
:::::::::::::::::: ::::::::::::::::::::::
XP_005 YVEKPKLDKGQRKGMRFKLCLQAQNFSPTESTKERAVMHQRQLSLPLTQSKSSPKRGFFR
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA1 EETDHLIKNLLGKRISKLINSSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EETDHLIKNLLGKRISKLINSSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWA
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA1 QRYLRWIPEAQILGGGQVATLSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRYLRWIPEAQILGGGQVATLSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSA
670 680 690 700 710 720
710 720 730 740
pF1KA1 RLSSLFPFALLQRHSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV
:::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLSSLFPFALLQRHSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV
730 740 750 760
>>XP_016865084 (OMIM: 606501) PREDICTED: myotubularin-re (544 aa)
initn: 3746 init1: 3746 opt: 3746 Z-score: 4300.9 bits: 806.0 E(85289): 0
Smith-Waterman score: 3746; 100.0% identity (100.0% similar) in 544 aa overlap (204-747:1-544)
180 190 200 210 220 230
pF1KA1 APKLLKRLFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGY
::::::::::::::::::::::::::::::
XP_016 MFDTLKDWCWELERTKGNMKYKAVSVNEGY
10 20 30
240 250 260 270 280 290
pF1KA1 KVCERLPAYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVCERLPAYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQ
40 50 60 70 80 90
300 310 320 330 340 350
pF1KA1 KSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKW
100 110 120 130 140 150
360 370 380 390 400 410
pF1KA1 FSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHC
160 170 180 190 200 210
420 430 440 450 460 470
pF1KA1 RTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFT
220 230 240 250 260 270
480 490 500 510 520 530
pF1KA1 ETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQ
280 290 300 310 320 330
540 550 560 570 580 590
pF1KA1 TLLKNPLYVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLLKNPLYVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGK
340 350 360 370 380 390
600 610 620 630 640 650
pF1KA1 RISKLINSSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RISKLINSSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQIL
400 410 420 430 440 450
660 670 680 690 700 710
pF1KA1 GGGQVATLSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGGQVATLSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQR
460 470 480 490 500 510
720 730 740
pF1KA1 HSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV
::::::::::::::::::::::::::::::::::
XP_016 HSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV
520 530 540
>>XP_016865083 (OMIM: 606501) PREDICTED: myotubularin-re (544 aa)
initn: 3746 init1: 3746 opt: 3746 Z-score: 4300.9 bits: 806.0 E(85289): 0
Smith-Waterman score: 3746; 100.0% identity (100.0% similar) in 544 aa overlap (204-747:1-544)
180 190 200 210 220 230
pF1KA1 APKLLKRLFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGY
::::::::::::::::::::::::::::::
XP_016 MFDTLKDWCWELERTKGNMKYKAVSVNEGY
10 20 30
240 250 260 270 280 290
pF1KA1 KVCERLPAYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVCERLPAYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQ
40 50 60 70 80 90
300 310 320 330 340 350
pF1KA1 KSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKW
100 110 120 130 140 150
360 370 380 390 400 410
pF1KA1 FSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHC
160 170 180 190 200 210
420 430 440 450 460 470
pF1KA1 RTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFT
220 230 240 250 260 270
480 490 500 510 520 530
pF1KA1 ETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQ
280 290 300 310 320 330
540 550 560 570 580 590
pF1KA1 TLLKNPLYVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLLKNPLYVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGK
340 350 360 370 380 390
600 610 620 630 640 650
pF1KA1 RISKLINSSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RISKLINSSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQIL
400 410 420 430 440 450
660 670 680 690 700 710
pF1KA1 GGGQVATLSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGGQVATLSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQR
460 470 480 490 500 510
720 730 740
pF1KA1 HSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV
::::::::::::::::::::::::::::::::::
XP_016 HSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV
520 530 540
>>XP_016865082 (OMIM: 606501) PREDICTED: myotubularin-re (544 aa)
initn: 3746 init1: 3746 opt: 3746 Z-score: 4300.9 bits: 806.0 E(85289): 0
Smith-Waterman score: 3746; 100.0% identity (100.0% similar) in 544 aa overlap (204-747:1-544)
180 190 200 210 220 230
pF1KA1 APKLLKRLFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGY
::::::::::::::::::::::::::::::
XP_016 MFDTLKDWCWELERTKGNMKYKAVSVNEGY
10 20 30
240 250 260 270 280 290
pF1KA1 KVCERLPAYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVCERLPAYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQ
40 50 60 70 80 90
300 310 320 330 340 350
pF1KA1 KSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKW
100 110 120 130 140 150
360 370 380 390 400 410
pF1KA1 FSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHC
160 170 180 190 200 210
420 430 440 450 460 470
pF1KA1 RTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFT
220 230 240 250 260 270
480 490 500 510 520 530
pF1KA1 ETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQ
280 290 300 310 320 330
540 550 560 570 580 590
pF1KA1 TLLKNPLYVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLLKNPLYVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGK
340 350 360 370 380 390
600 610 620 630 640 650
pF1KA1 RISKLINSSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RISKLINSSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQIL
400 410 420 430 440 450
660 670 680 690 700 710
pF1KA1 GGGQVATLSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGGQVATLSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQR
460 470 480 490 500 510
720 730 740
pF1KA1 HSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV
::::::::::::::::::::::::::::::::::
XP_016 HSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV
520 530 540
>>XP_011512360 (OMIM: 606501) PREDICTED: myotubularin-re (779 aa)
initn: 5076 init1: 3493 opt: 3493 Z-score: 4008.0 bits: 752.3 E(85289): 1.7e-216
Smith-Waterman score: 5015; 95.8% identity (95.8% similar) in 779 aa overlap (1-747:1-779)
10 20 30 40 50 60
pF1KA1 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
130 140 150 160 170 180
190 200 210 220 230
pF1KA1 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCER--
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCESVT
190 200 210 220 230 240
240 250 260
pF1KA1 ------------------------------LPAYFVVPTPLPEENVQRFQGHGIPIWCWS
::::::::::::::::::::::::::::::
XP_011 RWLASKRSSINRRQKEKPHLYLEGDLRQFGLPAYFVVPTPLPEENVQRFQGHGIPIWCWS
250 260 270 280 290 300
270 280 290 300 310 320
pF1KA1 CHNGSALLKMSALPKEQDDGILQIQKSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CHNGSALLKMSALPKEQDDGILQIQKSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQ
310 320 330 340 350 360
330 340 350 360 370 380
pF1KA1 TAYSKFKQLFLIDNSTEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAYSKFKQLFLIDNSTEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVL
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA1 LLEENASDLCCLISSLVQLMMDPHCRTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEENASDLCCLISSLVQLMMDPHCRTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEE
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA1 VPVFLLFLDCVWQLVHQHPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPVFLLFLDCVWQLVHQHPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREG
490 500 510 520 530 540
510 520 530 540 550 560
pF1KA1 QDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPLYVEKPKLDKGQRKGMRFKHQRQLSLPLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPLYVEKPKLDKGQRKGMRFKHQRQLSLPLT
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA1 QSKSSPKRGFFREETDHLIKNLLGKRISKLINSSDELQDNFREFYDSWHSKSTDYHGLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSKSSPKRGFFREETDHLIKNLLGKRISKLINSSDELQDNFREFYDSWHSKSTDYHGLLL
610 620 630 640 650 660
630 640 650 660 670 680
pF1KA1 PHIEGPEIKVWAQRYLRWIPEAQILGGGQVATLSKLLEMMEEVQSLQEKIDERHHSQQAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHIEGPEIKVWAQRYLRWIPEAQILGGGQVATLSKLLEMMEEVQSLQEKIDERHHSQQAP
670 680 690 700 710 720
690 700 710 720 730 740
pF1KA1 QAEAPCLLRNSARLSSLFPFALLQRHSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAEAPCLLRNSARLSSLFPFALLQRHSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV
730 740 750 760 770
>>NP_001281272 (OMIM: 606501) myotubularin-related prote (693 aa)
initn: 4710 init1: 3455 opt: 3459 Z-score: 3969.7 bits: 745.1 E(85289): 2.2e-214
Smith-Waterman score: 4606; 92.8% identity (92.8% similar) in 747 aa overlap (1-747:1-693)
10 20 30 40 50 60
pF1KA1 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 AYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 YKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 SWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 SLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 SDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPL
::::::::::::::::::::::::
NP_001 SDSLYIPIFSTFFFNSPHQKDTNM------------------------------------
490 500
550 560 570 580 590 600
pF1KA1 YVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLIN
::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------------HQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLIN
510 520 530 540
610 620 630 640 650 660
pF1KA1 SSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGQVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGQVAT
550 560 570 580 590 600
670 680 690 700 710 720
pF1KA1 LSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQRHSSKPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQRHSSKPVL
610 620 630 640 650 660
730 740
pF1KA1 PTSGWKALGDEDDLAKREDEFVDLGDV
:::::::::::::::::::::::::::
NP_001 PTSGWKALGDEDDLAKREDEFVDLGDV
670 680 690
>>NP_001281273 (OMIM: 606501) myotubularin-related prote (637 aa)
initn: 3063 init1: 3063 opt: 3063 Z-score: 3515.4 bits: 660.9 E(85289): 4.5e-189
Smith-Waterman score: 4102; 85.3% identity (85.3% similar) in 747 aa overlap (1-747:1-637)
10 20 30 40 50 60
pF1KA1 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 AYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 YKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 SWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 SLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVL
::::::::::::::::::::::::::::
NP_001 SLIQKEWVMGGHCFLDRCNHLRQNDKEE--------------------------------
430 440
490 500 510 520 530 540
pF1KA1 SDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPL
NP_001 ------------------------------------------------------------
550 560 570 580 590 600
pF1KA1 YVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLIN
::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------------HQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLIN
450 460 470 480 490
610 620 630 640 650 660
pF1KA1 SSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGQVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGQVAT
500 510 520 530 540 550
670 680 690 700 710 720
pF1KA1 LSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQRHSSKPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQRHSSKPVL
560 570 580 590 600 610
730 740
pF1KA1 PTSGWKALGDEDDLAKREDEFVDLGDV
:::::::::::::::::::::::::::
NP_001 PTSGWKALGDEDDLAKREDEFVDLGDV
620 630
>>XP_016865078 (OMIM: 606501) PREDICTED: myotubularin-re (691 aa)
initn: 3063 init1: 3063 opt: 3063 Z-score: 3514.9 bits: 660.9 E(85289): 4.8e-189
Smith-Waterman score: 4583; 92.5% identity (92.5% similar) in 747 aa overlap (1-747:1-691)
10 20 30 40 50 60
pF1KA1 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 AYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 YKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 SWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 SLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVL
::::::::::::::::::::::::::::
XP_016 SLIQKEWVMGGHCFLDRCNHLRQNDKEE--------------------------------
430 440
490 500 510 520 530 540
pF1KA1 SDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPL
::::::::::::::::::::::::::::::::::::
XP_016 ------------------------GREGQDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPL
450 460 470 480
550 560 570 580 590 600
pF1KA1 YVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLIN
490 500 510 520 530 540
610 620 630 640 650 660
pF1KA1 SSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGQVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGQVAT
550 560 570 580 590 600
670 680 690 700 710 720
pF1KA1 LSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQRHSSKPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQRHSSKPVL
610 620 630 640 650 660
730 740
pF1KA1 PTSGWKALGDEDDLAKREDEFVDLGDV
:::::::::::::::::::::::::::
XP_016 PTSGWKALGDEDDLAKREDEFVDLGDV
670 680 690
>>XP_011512361 (OMIM: 606501) PREDICTED: myotubularin-re (743 aa)
initn: 4297 init1: 1597 opt: 2728 Z-score: 3129.6 bits: 589.8 E(85289): 1.4e-167
Smith-Waterman score: 4451; 86.4% identity (86.4% similar) in 799 aa overlap (1-747:1-743)
10 20 30 40 50 60
pF1KA1 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
130 140 150 160 170 180
190 200 210 220 230
pF1KA1 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCER--
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCESVT
190 200 210 220 230 240
240 250 260
pF1KA1 ------------------------------LPAYFVVPTPLPEENVQRFQGHGIPIWCWS
::::::::::::::::::::::::::::::
XP_011 RWLASKRSSINRRQKEKPHLYLEGDLRQFGLPAYFVVPTPLPEENVQRFQGHGIPIWCWS
250 260 270 280 290 300
270 280 290 300 310 320
pF1KA1 CHNGSALLKMSALPKEQDDGILQIQKSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CHNGSALLKMSALPKEQDDGILQIQKSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQ
310 320 330 340 350 360
330 340 350 360 370 380
pF1KA1 TAYSKFKQLFLIDNSTEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAYSKFKQLFLIDNSTEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVL
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA1 LLEENASDLCCLISSLVQLMMDPHCRTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEENASDLCCLISSLVQLMMDPHCRTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEE
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA1 VPVFLLFLDCVWQLVHQHPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREG
::::
XP_011 --------------------------------------------------------GREG
510 520 530 540 550
pF1KA1 QDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPLYVEKPKLDKGQRKGMRFK----------
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPLYVEKPKLDKGQRKGMRFKLCLQAQNFSP
490 500 510 520 530 540
560 570 580 590 600
pF1KA1 ----------HQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLINSSDELQDN
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TESTKERAVMHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLINSSDELQDN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 FREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGQVATLSKLLEMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGQVATLSKLLEMM
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 EEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQRHSSKPVLPTSGWKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQRHSSKPVLPTSGWKAL
670 680 690 700 710 720
730 740
pF1KA1 GDEDDLAKREDEFVDLGDV
:::::::::::::::::::
XP_011 GDEDDLAKREDEFVDLGDV
730 740
747 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 21:49:42 2016 done: Wed Nov 2 21:49:44 2016
Total Scan time: 11.340 Total Display time: 0.220
Function used was FASTA [36.3.4 Apr, 2011]