FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1692, 833 aa 1>>>pF1KA1692 833 - 833 aa - 833 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4986+/-0.000497; mu= 14.7378+/- 0.031 mean_var=99.6210+/-20.511, 0's: 0 Z-trim(109.2): 146 B-trim: 0 in 0/53 Lambda= 0.128499 statistics sampled from 17277 (17412) to 17277 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.556), E-opt: 0.2 (0.204), width: 16 Scan time: 10.360 The best scores are: opt bits E(85289) NP_001161384 (OMIM: 609594) ventricular zone-expre ( 833) 5433 1018.9 0 NP_078897 (OMIM: 609594) ventricular zone-expresse ( 833) 5433 1018.9 0 XP_011511437 (OMIM: 609594) PREDICTED: ventricular ( 788) 5153 967.0 0 XP_011511436 (OMIM: 609594) PREDICTED: ventricular ( 844) 5153 967.0 0 NP_001161383 (OMIM: 609594) ventricular zone-expre ( 788) 4054 763.2 0 NP_001161387 (OMIM: 609594) ventricular zone-expre ( 213) 1138 222.3 1.8e-57 NP_001161388 (OMIM: 609594) ventricular zone-expre ( 213) 1138 222.3 1.8e-57 NP_001161389 (OMIM: 609594) ventricular zone-expre ( 177) 1130 220.8 4.3e-57 >>NP_001161384 (OMIM: 609594) ventricular zone-expressed (833 aa) initn: 5433 init1: 5433 opt: 5433 Z-score: 5447.2 bits: 1018.9 E(85289): 0 Smith-Waterman score: 5433; 100.0% identity (100.0% similar) in 833 aa overlap (1-833:1-833) 10 20 30 40 50 60 pF1KA1 MHQLFRLVLGQKDLSRAGDLFSLDDSEIEDSLTEALEQIKIISSSSDYQTNNNDQAVVEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MHQLFRLVLGQKDLSRAGDLFSLDDSEIEDSLTEALEQIKIISSSSDYQTNNNDQAVVEI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 CITRITTAIRETESIEKHAKALVGLWDSCLEHNLRPFGKDEDTPHAKIASDIMSCILQNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CITRITTAIRETESIEKHAKALVGLWDSCLEHNLRPFGKDEDTPHAKIASDIMSCILQNY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 NRPPVMALAIPIAVKFLHRGNKELCRNMSNYLSLAAITKADLLADHTEVIVKSILQGNTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRPPVMALAIPIAVKFLHRGNKELCRNMSNYLSLAAITKADLLADHTEVIVKSILQGNTM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 LLRVLPAVYEKQPQPINRHLTELLALMSQLEQPEQYHLLRLLHVAAKKKQLEVVQKCIPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLRVLPAVYEKQPQPINRHLTELLALMSQLEQPEQYHLLRLLHVAAKKKQLEVVQKCIPF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 LIGHLKDSTHNDIILNILIEIAVYEPVALNSFLPMLKEIGERFPYLTGQMARIYGAVGHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIGHLKDSTHNDIILNILIEIAVYEPVALNSFLPMLKEIGERFPYLTGQMARIYGAVGHV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 DEERARSCLTYLVSQLANMEHSFHHILLLEIKSITDTFSSILGPQSRDIFRMSNSFTAIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DEERARSCLTYLVSQLANMEHSFHHILLLEIKSITDTFSSILGPQSRDIFRMSNSFTAIA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KLLTRQLENTKAGSGRRKISTEIEFPEKLEETKLIVTENEDHEKLQVKIQAFEDKINAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLLTRQLENTKAGSGRRKISTEIEFPEKLEETKLIVTENEDHEKLQVKIQAFEDKINAGS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 NTPGSIRRYSLGQVSKEERKNIRFNRSKSLAFHTMLTKGVGSDDGEDENRGDIPASISLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NTPGSIRRYSLGQVSKEERKNIRFNRSKSLAFHTMLTKGVGSDDGEDENRGDIPASISLS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 EIDPLGQGNDKLPFKTDTERSQLGESSVSYPNIIHIDSENLSETVKENSQEETPETTASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EIDPLGQGNDKLPFKTDTERSQLGESSVSYPNIIHIDSENLSETVKENSQEETPETTASP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 IEYQDKLYLHLKKNLSKVKAYAMEIGKKIPVPDQCTIEDTVRSCVAKLFFTCSLKGHYCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEYQDKLYLHLKKNLSKVKAYAMEIGKKIPVPDQCTIEDTVRSCVAKLFFTCSLKGHYCL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 YSKSSFILISQEPQPWIQIMFLFQQSLFPEPLSIQSHSVQFLRALWEKTQAGGAHSFETA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YSKSSFILISQEPQPWIQIMFLFQQSLFPEPLSIQSHSVQFLRALWEKTQAGGAHSFETA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 MMESTFPQQKDLDQVQLHLEEVRFFDVFGFSETAGAWQCFMCNNPEKATVVNQDGQPLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMESTFPQQKDLDQVQLHLEEVRFFDVFGFSETAGAWQCFMCNNPEKATVVNQDGQPLIE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 GKLKEKQVRWKFIKRWKTRYFTLAGNQLLFQKGKSKDDPDDCPIELSKVQSVKAVAKKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKLKEKQVRWKFIKRWKTRYFTLAGNQLLFQKGKSKDDPDDCPIELSKVQSVKAVAKKRR 730 740 750 760 770 780 790 800 810 820 830 pF1KA1 DRSLPRAFEIFTDNKTYVFKAKDEKNAEEWLQCINVAVAQAKERESREVTTYL ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRSLPRAFEIFTDNKTYVFKAKDEKNAEEWLQCINVAVAQAKERESREVTTYL 790 800 810 820 830 >>NP_078897 (OMIM: 609594) ventricular zone-expressed PH (833 aa) initn: 5433 init1: 5433 opt: 5433 Z-score: 5447.2 bits: 1018.9 E(85289): 0 Smith-Waterman score: 5433; 100.0% identity (100.0% similar) in 833 aa overlap (1-833:1-833) 10 20 30 40 50 60 pF1KA1 MHQLFRLVLGQKDLSRAGDLFSLDDSEIEDSLTEALEQIKIISSSSDYQTNNNDQAVVEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 MHQLFRLVLGQKDLSRAGDLFSLDDSEIEDSLTEALEQIKIISSSSDYQTNNNDQAVVEI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 CITRITTAIRETESIEKHAKALVGLWDSCLEHNLRPFGKDEDTPHAKIASDIMSCILQNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 CITRITTAIRETESIEKHAKALVGLWDSCLEHNLRPFGKDEDTPHAKIASDIMSCILQNY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 NRPPVMALAIPIAVKFLHRGNKELCRNMSNYLSLAAITKADLLADHTEVIVKSILQGNTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 NRPPVMALAIPIAVKFLHRGNKELCRNMSNYLSLAAITKADLLADHTEVIVKSILQGNTM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 LLRVLPAVYEKQPQPINRHLTELLALMSQLEQPEQYHLLRLLHVAAKKKQLEVVQKCIPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 LLRVLPAVYEKQPQPINRHLTELLALMSQLEQPEQYHLLRLLHVAAKKKQLEVVQKCIPF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 LIGHLKDSTHNDIILNILIEIAVYEPVALNSFLPMLKEIGERFPYLTGQMARIYGAVGHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 LIGHLKDSTHNDIILNILIEIAVYEPVALNSFLPMLKEIGERFPYLTGQMARIYGAVGHV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 DEERARSCLTYLVSQLANMEHSFHHILLLEIKSITDTFSSILGPQSRDIFRMSNSFTAIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 DEERARSCLTYLVSQLANMEHSFHHILLLEIKSITDTFSSILGPQSRDIFRMSNSFTAIA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KLLTRQLENTKAGSGRRKISTEIEFPEKLEETKLIVTENEDHEKLQVKIQAFEDKINAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 KLLTRQLENTKAGSGRRKISTEIEFPEKLEETKLIVTENEDHEKLQVKIQAFEDKINAGS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 NTPGSIRRYSLGQVSKEERKNIRFNRSKSLAFHTMLTKGVGSDDGEDENRGDIPASISLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 NTPGSIRRYSLGQVSKEERKNIRFNRSKSLAFHTMLTKGVGSDDGEDENRGDIPASISLS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 EIDPLGQGNDKLPFKTDTERSQLGESSVSYPNIIHIDSENLSETVKENSQEETPETTASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 EIDPLGQGNDKLPFKTDTERSQLGESSVSYPNIIHIDSENLSETVKENSQEETPETTASP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 IEYQDKLYLHLKKNLSKVKAYAMEIGKKIPVPDQCTIEDTVRSCVAKLFFTCSLKGHYCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 IEYQDKLYLHLKKNLSKVKAYAMEIGKKIPVPDQCTIEDTVRSCVAKLFFTCSLKGHYCL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 YSKSSFILISQEPQPWIQIMFLFQQSLFPEPLSIQSHSVQFLRALWEKTQAGGAHSFETA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 YSKSSFILISQEPQPWIQIMFLFQQSLFPEPLSIQSHSVQFLRALWEKTQAGGAHSFETA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 MMESTFPQQKDLDQVQLHLEEVRFFDVFGFSETAGAWQCFMCNNPEKATVVNQDGQPLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 MMESTFPQQKDLDQVQLHLEEVRFFDVFGFSETAGAWQCFMCNNPEKATVVNQDGQPLIE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 GKLKEKQVRWKFIKRWKTRYFTLAGNQLLFQKGKSKDDPDDCPIELSKVQSVKAVAKKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 GKLKEKQVRWKFIKRWKTRYFTLAGNQLLFQKGKSKDDPDDCPIELSKVQSVKAVAKKRR 730 740 750 760 770 780 790 800 810 820 830 pF1KA1 DRSLPRAFEIFTDNKTYVFKAKDEKNAEEWLQCINVAVAQAKERESREVTTYL ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 DRSLPRAFEIFTDNKTYVFKAKDEKNAEEWLQCINVAVAQAKERESREVTTYL 790 800 810 820 830 >>XP_011511437 (OMIM: 609594) PREDICTED: ventricular zon (788 aa) initn: 5153 init1: 5153 opt: 5153 Z-score: 5167.0 bits: 967.0 E(85289): 0 Smith-Waterman score: 5153; 100.0% identity (100.0% similar) in 787 aa overlap (47-833:2-788) 20 30 40 50 60 70 pF1KA1 AGDLFSLDDSEIEDSLTEALEQIKIISSSSDYQTNNNDQAVVEICITRITTAIRETESIE :::::::::::::::::::::::::::::: XP_011 MDYQTNNNDQAVVEICITRITTAIRETESIE 10 20 30 80 90 100 110 120 130 pF1KA1 KHAKALVGLWDSCLEHNLRPFGKDEDTPHAKIASDIMSCILQNYNRPPVMALAIPIAVKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KHAKALVGLWDSCLEHNLRPFGKDEDTPHAKIASDIMSCILQNYNRPPVMALAIPIAVKF 40 50 60 70 80 90 140 150 160 170 180 190 pF1KA1 LHRGNKELCRNMSNYLSLAAITKADLLADHTEVIVKSILQGNTMLLRVLPAVYEKQPQPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LHRGNKELCRNMSNYLSLAAITKADLLADHTEVIVKSILQGNTMLLRVLPAVYEKQPQPI 100 110 120 130 140 150 200 210 220 230 240 250 pF1KA1 NRHLTELLALMSQLEQPEQYHLLRLLHVAAKKKQLEVVQKCIPFLIGHLKDSTHNDIILN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NRHLTELLALMSQLEQPEQYHLLRLLHVAAKKKQLEVVQKCIPFLIGHLKDSTHNDIILN 160 170 180 190 200 210 260 270 280 290 300 310 pF1KA1 ILIEIAVYEPVALNSFLPMLKEIGERFPYLTGQMARIYGAVGHVDEERARSCLTYLVSQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILIEIAVYEPVALNSFLPMLKEIGERFPYLTGQMARIYGAVGHVDEERARSCLTYLVSQL 220 230 240 250 260 270 320 330 340 350 360 370 pF1KA1 ANMEHSFHHILLLEIKSITDTFSSILGPQSRDIFRMSNSFTAIAKLLTRQLENTKAGSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ANMEHSFHHILLLEIKSITDTFSSILGPQSRDIFRMSNSFTAIAKLLTRQLENTKAGSGR 280 290 300 310 320 330 380 390 400 410 420 430 pF1KA1 RKISTEIEFPEKLEETKLIVTENEDHEKLQVKIQAFEDKINAGSNTPGSIRRYSLGQVSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKISTEIEFPEKLEETKLIVTENEDHEKLQVKIQAFEDKINAGSNTPGSIRRYSLGQVSK 340 350 360 370 380 390 440 450 460 470 480 490 pF1KA1 EERKNIRFNRSKSLAFHTMLTKGVGSDDGEDENRGDIPASISLSEIDPLGQGNDKLPFKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EERKNIRFNRSKSLAFHTMLTKGVGSDDGEDENRGDIPASISLSEIDPLGQGNDKLPFKT 400 410 420 430 440 450 500 510 520 530 540 550 pF1KA1 DTERSQLGESSVSYPNIIHIDSENLSETVKENSQEETPETTASPIEYQDKLYLHLKKNLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTERSQLGESSVSYPNIIHIDSENLSETVKENSQEETPETTASPIEYQDKLYLHLKKNLS 460 470 480 490 500 510 560 570 580 590 600 610 pF1KA1 KVKAYAMEIGKKIPVPDQCTIEDTVRSCVAKLFFTCSLKGHYCLYSKSSFILISQEPQPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVKAYAMEIGKKIPVPDQCTIEDTVRSCVAKLFFTCSLKGHYCLYSKSSFILISQEPQPW 520 530 540 550 560 570 620 630 640 650 660 670 pF1KA1 IQIMFLFQQSLFPEPLSIQSHSVQFLRALWEKTQAGGAHSFETAMMESTFPQQKDLDQVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQIMFLFQQSLFPEPLSIQSHSVQFLRALWEKTQAGGAHSFETAMMESTFPQQKDLDQVQ 580 590 600 610 620 630 680 690 700 710 720 730 pF1KA1 LHLEEVRFFDVFGFSETAGAWQCFMCNNPEKATVVNQDGQPLIEGKLKEKQVRWKFIKRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LHLEEVRFFDVFGFSETAGAWQCFMCNNPEKATVVNQDGQPLIEGKLKEKQVRWKFIKRW 640 650 660 670 680 690 740 750 760 770 780 790 pF1KA1 KTRYFTLAGNQLLFQKGKSKDDPDDCPIELSKVQSVKAVAKKRRDRSLPRAFEIFTDNKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTRYFTLAGNQLLFQKGKSKDDPDDCPIELSKVQSVKAVAKKRRDRSLPRAFEIFTDNKT 700 710 720 730 740 750 800 810 820 830 pF1KA1 YVFKAKDEKNAEEWLQCINVAVAQAKERESREVTTYL ::::::::::::::::::::::::::::::::::::: XP_011 YVFKAKDEKNAEEWLQCINVAVAQAKERESREVTTYL 760 770 780 >>XP_011511436 (OMIM: 609594) PREDICTED: ventricular zon (844 aa) initn: 5153 init1: 5153 opt: 5153 Z-score: 5166.5 bits: 967.0 E(85289): 0 Smith-Waterman score: 5153; 100.0% identity (100.0% similar) in 787 aa overlap (47-833:58-844) 20 30 40 50 60 70 pF1KA1 AGDLFSLDDSEIEDSLTEALEQIKIISSSSDYQTNNNDQAVVEICITRITTAIRETESIE :::::::::::::::::::::::::::::: XP_011 LERMRWGERRESRKKYVLNGRSTFLDYFLCDYQTNNNDQAVVEICITRITTAIRETESIE 30 40 50 60 70 80 80 90 100 110 120 130 pF1KA1 KHAKALVGLWDSCLEHNLRPFGKDEDTPHAKIASDIMSCILQNYNRPPVMALAIPIAVKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KHAKALVGLWDSCLEHNLRPFGKDEDTPHAKIASDIMSCILQNYNRPPVMALAIPIAVKF 90 100 110 120 130 140 140 150 160 170 180 190 pF1KA1 LHRGNKELCRNMSNYLSLAAITKADLLADHTEVIVKSILQGNTMLLRVLPAVYEKQPQPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LHRGNKELCRNMSNYLSLAAITKADLLADHTEVIVKSILQGNTMLLRVLPAVYEKQPQPI 150 160 170 180 190 200 200 210 220 230 240 250 pF1KA1 NRHLTELLALMSQLEQPEQYHLLRLLHVAAKKKQLEVVQKCIPFLIGHLKDSTHNDIILN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NRHLTELLALMSQLEQPEQYHLLRLLHVAAKKKQLEVVQKCIPFLIGHLKDSTHNDIILN 210 220 230 240 250 260 260 270 280 290 300 310 pF1KA1 ILIEIAVYEPVALNSFLPMLKEIGERFPYLTGQMARIYGAVGHVDEERARSCLTYLVSQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILIEIAVYEPVALNSFLPMLKEIGERFPYLTGQMARIYGAVGHVDEERARSCLTYLVSQL 270 280 290 300 310 320 320 330 340 350 360 370 pF1KA1 ANMEHSFHHILLLEIKSITDTFSSILGPQSRDIFRMSNSFTAIAKLLTRQLENTKAGSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ANMEHSFHHILLLEIKSITDTFSSILGPQSRDIFRMSNSFTAIAKLLTRQLENTKAGSGR 330 340 350 360 370 380 380 390 400 410 420 430 pF1KA1 RKISTEIEFPEKLEETKLIVTENEDHEKLQVKIQAFEDKINAGSNTPGSIRRYSLGQVSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKISTEIEFPEKLEETKLIVTENEDHEKLQVKIQAFEDKINAGSNTPGSIRRYSLGQVSK 390 400 410 420 430 440 440 450 460 470 480 490 pF1KA1 EERKNIRFNRSKSLAFHTMLTKGVGSDDGEDENRGDIPASISLSEIDPLGQGNDKLPFKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EERKNIRFNRSKSLAFHTMLTKGVGSDDGEDENRGDIPASISLSEIDPLGQGNDKLPFKT 450 460 470 480 490 500 500 510 520 530 540 550 pF1KA1 DTERSQLGESSVSYPNIIHIDSENLSETVKENSQEETPETTASPIEYQDKLYLHLKKNLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTERSQLGESSVSYPNIIHIDSENLSETVKENSQEETPETTASPIEYQDKLYLHLKKNLS 510 520 530 540 550 560 560 570 580 590 600 610 pF1KA1 KVKAYAMEIGKKIPVPDQCTIEDTVRSCVAKLFFTCSLKGHYCLYSKSSFILISQEPQPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVKAYAMEIGKKIPVPDQCTIEDTVRSCVAKLFFTCSLKGHYCLYSKSSFILISQEPQPW 570 580 590 600 610 620 620 630 640 650 660 670 pF1KA1 IQIMFLFQQSLFPEPLSIQSHSVQFLRALWEKTQAGGAHSFETAMMESTFPQQKDLDQVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQIMFLFQQSLFPEPLSIQSHSVQFLRALWEKTQAGGAHSFETAMMESTFPQQKDLDQVQ 630 640 650 660 670 680 680 690 700 710 720 730 pF1KA1 LHLEEVRFFDVFGFSETAGAWQCFMCNNPEKATVVNQDGQPLIEGKLKEKQVRWKFIKRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LHLEEVRFFDVFGFSETAGAWQCFMCNNPEKATVVNQDGQPLIEGKLKEKQVRWKFIKRW 690 700 710 720 730 740 740 750 760 770 780 790 pF1KA1 KTRYFTLAGNQLLFQKGKSKDDPDDCPIELSKVQSVKAVAKKRRDRSLPRAFEIFTDNKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTRYFTLAGNQLLFQKGKSKDDPDDCPIELSKVQSVKAVAKKRRDRSLPRAFEIFTDNKT 750 760 770 780 790 800 800 810 820 830 pF1KA1 YVFKAKDEKNAEEWLQCINVAVAQAKERESREVTTYL ::::::::::::::::::::::::::::::::::::: XP_011 YVFKAKDEKNAEEWLQCINVAVAQAKERESREVTTYL 810 820 830 840 >>NP_001161383 (OMIM: 609594) ventricular zone-expressed (788 aa) initn: 4037 init1: 4037 opt: 4054 Z-score: 4065.9 bits: 763.2 E(85289): 0 Smith-Waterman score: 5033; 94.6% identity (94.6% similar) in 833 aa overlap (1-833:1-788) 10 20 30 40 50 60 pF1KA1 MHQLFRLVLGQKDLSRAGDLFSLDDSEIEDSLTEALEQIKIISSSSDYQTNNNDQAVVEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MHQLFRLVLGQKDLSRAGDLFSLDDSEIEDSLTEALEQIKIISSSSDYQTNNNDQAVVEI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 CITRITTAIRETESIEKHAKALVGLWDSCLEHNLRPFGKDEDTPHAKIASDIMSCILQNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CITRITTAIRETESIEKHAKALVGLWDSCLEHNLRPFGKDEDTPHAKIASDIMSCILQNY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 NRPPVMALAIPIAVKFLHRGNKELCRNMSNYLSLAAITKADLLADHTEVIVKSILQGNTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRPPVMALAIPIAVKFLHRGNKELCRNMSNYLSLAAITKADLLADHTEVIVKSILQGNTM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 LLRVLPAVYEKQPQPINRHLTELLALMSQLEQPEQYHLLRLLHVAAKKKQLEVVQKCIPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLRVLPAVYEKQPQPINRHLTELLALMSQLEQPEQYHLLRLLHVAAKKKQLEVVQKCIPF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 LIGHLKDSTHNDIILNILIEIAVYEPVALNSFLPMLKEIGERFPYLTGQMARIYGAVGHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIGHLKDSTHNDIILNILIEIAVYEPVALNSFLPMLKEIGERFPYLTGQMARIYGAVGHV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 DEERARSCLTYLVSQLANMEHSFHHILLLEIKSITDTFSSILGPQSRDIFRMSNSFTAIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DEERARSCLTYLVSQLANMEHSFHHILLLEIKSITDTFSSILGPQSRDIFRMSNSFTAIA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KLLTRQLENTKAGSGRRKISTEIEFPEKLEETKLIVTENEDHEKLQVKIQAFEDKINAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLLTRQLENTKAGSGRRKISTEIEFPEKLEETKLIVTENEDHEKLQVKIQAFEDKINAGS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 NTPGSIRRYSLGQVSKEERKNIRFNRSKSLAFHTMLTKGVGSDDGEDENRGDIPASISLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NTPGSIRRYSLGQVSKEERKNIRFNRSKSLAFHTMLTKGVGSDDGEDENRGDIPASISLS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 EIDPLGQGNDKLPFKTDTERSQLGESSVSYPNIIHIDSENLSETVKENSQEETPETTASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EIDPLGQGNDKLPFKTDTERSQLGESSVSYPNIIHIDSENLSETVKENSQEETPETTASP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 IEYQDKLYLHLKKNLSKVKAYAMEIGKKIPVPDQCTIEDTVRSCVAKLFFTCSLKGHYCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEYQDKLYLHLKKNLSKVKAYAMEIGKKIPVPDQCTIEDTVRSCVAKLFFTCSLKGHYCL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 YSKSSFILISQEPQPWIQIMFLFQQSLFPEPLSIQSHSVQFLRALWEKTQAGGAHSFETA ::::::::::::::::::::::::: NP_001 YSKSSFILISQEPQPWIQIMFLFQQ----------------------------------- 610 620 670 680 690 700 710 720 pF1KA1 MMESTFPQQKDLDQVQLHLEEVRFFDVFGFSETAGAWQCFMCNNPEKATVVNQDGQPLIE :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ----------DLDQVQLHLEEVRFFDVFGFSETAGAWQCFMCNNPEKATVVNQDGQPLIE 630 640 650 660 670 730 740 750 760 770 780 pF1KA1 GKLKEKQVRWKFIKRWKTRYFTLAGNQLLFQKGKSKDDPDDCPIELSKVQSVKAVAKKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKLKEKQVRWKFIKRWKTRYFTLAGNQLLFQKGKSKDDPDDCPIELSKVQSVKAVAKKRR 680 690 700 710 720 730 790 800 810 820 830 pF1KA1 DRSLPRAFEIFTDNKTYVFKAKDEKNAEEWLQCINVAVAQAKERESREVTTYL ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRSLPRAFEIFTDNKTYVFKAKDEKNAEEWLQCINVAVAQAKERESREVTTYL 740 750 760 770 780 >>NP_001161387 (OMIM: 609594) ventricular zone-expressed (213 aa) initn: 1138 init1: 1138 opt: 1138 Z-score: 1152.9 bits: 222.3 E(85289): 1.8e-57 Smith-Waterman score: 1138; 100.0% identity (100.0% similar) in 177 aa overlap (1-177:1-177) 10 20 30 40 50 60 pF1KA1 MHQLFRLVLGQKDLSRAGDLFSLDDSEIEDSLTEALEQIKIISSSSDYQTNNNDQAVVEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MHQLFRLVLGQKDLSRAGDLFSLDDSEIEDSLTEALEQIKIISSSSDYQTNNNDQAVVEI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 CITRITTAIRETESIEKHAKALVGLWDSCLEHNLRPFGKDEDTPHAKIASDIMSCILQNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CITRITTAIRETESIEKHAKALVGLWDSCLEHNLRPFGKDEDTPHAKIASDIMSCILQNY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 NRPPVMALAIPIAVKFLHRGNKELCRNMSNYLSLAAITKADLLADHTEVIVKSILQGNTM ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRPPVMALAIPIAVKFLHRGNKELCRNMSNYLSLAAITKADLLADHTEVIVKSILQGMVR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 LLRVLPAVYEKQPQPINRHLTELLALMSQLEQPEQYHLLRLLHVAAKKKQLEVVQKCIPF NP_001 KLSLGTCFGRYLKVFSSSIYGLWEARPRVLEAN 190 200 210 >>NP_001161388 (OMIM: 609594) ventricular zone-expressed (213 aa) initn: 1138 init1: 1138 opt: 1138 Z-score: 1152.9 bits: 222.3 E(85289): 1.8e-57 Smith-Waterman score: 1138; 100.0% identity (100.0% similar) in 177 aa overlap (1-177:1-177) 10 20 30 40 50 60 pF1KA1 MHQLFRLVLGQKDLSRAGDLFSLDDSEIEDSLTEALEQIKIISSSSDYQTNNNDQAVVEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MHQLFRLVLGQKDLSRAGDLFSLDDSEIEDSLTEALEQIKIISSSSDYQTNNNDQAVVEI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 CITRITTAIRETESIEKHAKALVGLWDSCLEHNLRPFGKDEDTPHAKIASDIMSCILQNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CITRITTAIRETESIEKHAKALVGLWDSCLEHNLRPFGKDEDTPHAKIASDIMSCILQNY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 NRPPVMALAIPIAVKFLHRGNKELCRNMSNYLSLAAITKADLLADHTEVIVKSILQGNTM ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRPPVMALAIPIAVKFLHRGNKELCRNMSNYLSLAAITKADLLADHTEVIVKSILQGMVR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 LLRVLPAVYEKQPQPINRHLTELLALMSQLEQPEQYHLLRLLHVAAKKKQLEVVQKCIPF NP_001 KLSLGTCFGRYLKVFSSSIYGLWEARPRVLEAN 190 200 210 >>NP_001161389 (OMIM: 609594) ventricular zone-expressed (177 aa) initn: 1130 init1: 1130 opt: 1130 Z-score: 1146.1 bits: 220.8 E(85289): 4.3e-57 Smith-Waterman score: 1130; 100.0% identity (100.0% similar) in 176 aa overlap (1-176:1-176) 10 20 30 40 50 60 pF1KA1 MHQLFRLVLGQKDLSRAGDLFSLDDSEIEDSLTEALEQIKIISSSSDYQTNNNDQAVVEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MHQLFRLVLGQKDLSRAGDLFSLDDSEIEDSLTEALEQIKIISSSSDYQTNNNDQAVVEI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 CITRITTAIRETESIEKHAKALVGLWDSCLEHNLRPFGKDEDTPHAKIASDIMSCILQNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CITRITTAIRETESIEKHAKALVGLWDSCLEHNLRPFGKDEDTPHAKIASDIMSCILQNY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 NRPPVMALAIPIAVKFLHRGNKELCRNMSNYLSLAAITKADLLADHTEVIVKSILQGNTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRPPVMALAIPIAVKFLHRGNKELCRNMSNYLSLAAITKADLLADHTEVIVKSILQV 130 140 150 160 170 190 200 210 220 230 240 pF1KA1 LLRVLPAVYEKQPQPINRHLTELLALMSQLEQPEQYHLLRLLHVAAKKKQLEVVQKCIPF 833 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 21:51:59 2016 done: Wed Nov 2 21:52:00 2016 Total Scan time: 10.360 Total Display time: 0.140 Function used was FASTA [36.3.4 Apr, 2011]