FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1700, 665 aa 1>>>pF1KA1700 665 - 665 aa - 665 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.3086+/-0.000405; mu= 6.0568+/- 0.025 mean_var=167.1479+/-33.981, 0's: 0 Z-trim(116.7): 113 B-trim: 53 in 1/54 Lambda= 0.099203 statistics sampled from 27899 (28013) to 27899 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.328), width: 16 Scan time: 11.960 The best scores are: opt bits E(85289) XP_011519158 (OMIM: 607175) PREDICTED: dual specif ( 665) 4372 638.3 2.7e-182 XP_011519159 (OMIM: 607175) PREDICTED: dual specif ( 665) 4372 638.3 2.7e-182 XP_006719218 (OMIM: 607175) PREDICTED: dual specif ( 665) 4372 638.3 2.7e-182 NP_085143 (OMIM: 607175) dual specificity protein ( 665) 4372 638.3 2.7e-182 XP_005253545 (OMIM: 607175) PREDICTED: dual specif ( 517) 3214 472.5 1.7e-132 XP_016875477 (OMIM: 607175) PREDICTED: dual specif ( 517) 3214 472.5 1.7e-132 NP_004411 (OMIM: 602038) dual specificity protein ( 625) 1483 224.8 7.4e-58 XP_011518234 (OMIM: 602038) PREDICTED: dual specif ( 625) 1483 224.8 7.4e-58 XP_011518235 (OMIM: 602038) PREDICTED: dual specif ( 625) 1483 224.8 7.4e-58 NP_004409 (OMIM: 603068) dual specificity protein ( 314) 473 80.1 1.4e-14 XP_016859035 (OMIM: 603068) PREDICTED: dual specif ( 342) 462 78.6 4.4e-14 NP_001938 (OMIM: 602749) dual specificity protein ( 419) 462 78.6 5.2e-14 NP_001937 (OMIM: 602748,615269) dual specificity p ( 381) 446 76.3 2.3e-13 NP_001305432 (OMIM: 300134) dual specificity prote ( 384) 439 75.3 4.7e-13 XP_011529426 (OMIM: 300134) PREDICTED: dual specif ( 384) 439 75.3 4.7e-13 NP_001386 (OMIM: 300134) dual specificity protein ( 384) 439 75.3 4.7e-13 XP_011529425 (OMIM: 300134) PREDICTED: dual specif ( 415) 439 75.3 5e-13 NP_004408 (OMIM: 600714) dual specificity protein ( 367) 433 74.4 8.3e-13 NP_009138 (OMIM: 608867) dual specificity protein ( 482) 422 72.9 3.1e-12 NP_476499 (OMIM: 602747) dual specificity protein ( 303) 404 70.2 1.3e-11 XP_011542730 (OMIM: 602747) PREDICTED: dual specif ( 303) 404 70.2 1.3e-11 NP_001385 (OMIM: 602747) dual specificity protein ( 394) 402 70.0 1.9e-11 NP_004410 (OMIM: 603069) dual specificity protein ( 384) 365 64.7 7.3e-10 XP_011522536 (OMIM: 606618) PREDICTED: dual specif ( 198) 342 61.2 4.1e-09 NP_008957 (OMIM: 606618) dual specificity protein ( 198) 342 61.2 4.1e-09 XP_005257034 (OMIM: 606618) PREDICTED: dual specif ( 198) 342 61.2 4.1e-09 XP_016873431 (OMIM: 606780) PREDICTED: protein pho ( 559) 326 59.2 4.8e-08 NP_060327 (OMIM: 606780) protein phosphatase Sling ( 659) 326 59.3 5.4e-08 XP_016880741 (OMIM: 606779) PREDICTED: protein pho (1328) 317 58.1 2.4e-07 XP_011523709 (OMIM: 606779) PREDICTED: protein pho (1347) 317 58.1 2.4e-07 XP_011523708 (OMIM: 606779) PREDICTED: protein pho (1347) 317 58.1 2.4e-07 XP_011523707 (OMIM: 606779) PREDICTED: protein pho (1394) 317 58.2 2.5e-07 XP_006722212 (OMIM: 606779) PREDICTED: protein pho (1401) 317 58.2 2.5e-07 XP_011523706 (OMIM: 606779) PREDICTED: protein pho (1405) 317 58.2 2.5e-07 NP_203747 (OMIM: 606779) protein phosphatase Sling (1423) 317 58.2 2.5e-07 XP_005258116 (OMIM: 606779) PREDICTED: protein pho (1430) 317 58.2 2.5e-07 XP_011523704 (OMIM: 606779) PREDICTED: protein pho (1430) 317 58.2 2.5e-07 XP_016880740 (OMIM: 606779) PREDICTED: protein pho (1449) 317 58.2 2.5e-07 XP_005258115 (OMIM: 606779) PREDICTED: protein pho (1450) 317 58.2 2.5e-07 NP_001269058 (OMIM: 606779) protein phosphatase Sl (1450) 317 58.2 2.5e-07 NP_001154802 (OMIM: 606778) protein phosphatase Sl ( 692) 306 56.4 4.1e-07 NP_001154803 (OMIM: 606778) protein phosphatase Sl ( 703) 306 56.4 4.2e-07 XP_016874981 (OMIM: 606778) PREDICTED: protein pho ( 923) 306 56.5 5.2e-07 XP_005269042 (OMIM: 606778) PREDICTED: protein pho ( 969) 306 56.5 5.4e-07 XP_011536802 (OMIM: 606778) PREDICTED: protein pho ( 969) 306 56.5 5.4e-07 XP_011536803 (OMIM: 606778) PREDICTED: protein pho ( 969) 306 56.5 5.4e-07 XP_016880743 (OMIM: 606779) PREDICTED: protein pho ( 480) 300 55.5 5.5e-07 XP_016874980 (OMIM: 606778) PREDICTED: protein pho (1033) 306 56.5 5.7e-07 XP_005269041 (OMIM: 606778) PREDICTED: protein pho (1049) 306 56.5 5.8e-07 NP_061857 (OMIM: 606778) protein phosphatase Sling (1049) 306 56.5 5.8e-07 >>XP_011519158 (OMIM: 607175) PREDICTED: dual specificit (665 aa) initn: 4372 init1: 4372 opt: 4372 Z-score: 3393.9 bits: 638.3 E(85289): 2.7e-182 Smith-Waterman score: 4372; 100.0% identity (100.0% similar) in 665 aa overlap (1-665:1-665) 10 20 30 40 50 60 pF1KA1 MAHEMIGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAHEMIGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 DKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVHL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKELM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 LVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 QTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRPVHPASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRPVHPASV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 PSVPSVQPSLLEDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSVPSVQPSLLEDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 SSSEDALEYYKPSTTLDGTNKLCQFSPVQELSEQTPETSPDKEEASIPKKLQTARPSDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSSEDALEYYKPSTTLDGTNKLCQFSPVQELSEQTPETSPDKEEASIPKKLQTARPSDSQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SKRLHSVRTSSSGTAQRSLLSPLHRSGSVEDNYHTSFLFGLSTSQQHLTKSAGLGLKGWH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKRLHSVRTSSSGTAQRSLLSPLHRSGSVEDNYHTSFLFGLSTSQQHLTKSAGLGLKGWH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SDILAPQTSTPSLTSSWYFATESSHFYSASAIYGGSASYSAYSCSQLPTCGDQVYSVRRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDILAPQTSTPSLTSSWYFATESSHFYSASAIYGGSASYSAYSCSQLPTCGDQVYSVRRR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 QKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSME 610 620 630 640 650 660 pF1KA1 IIEVS ::::: XP_011 IIEVS >>XP_011519159 (OMIM: 607175) PREDICTED: dual specificit (665 aa) initn: 4372 init1: 4372 opt: 4372 Z-score: 3393.9 bits: 638.3 E(85289): 2.7e-182 Smith-Waterman score: 4372; 100.0% identity (100.0% similar) in 665 aa overlap (1-665:1-665) 10 20 30 40 50 60 pF1KA1 MAHEMIGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAHEMIGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 DKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVHL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKELM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 LVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 QTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRPVHPASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRPVHPASV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 PSVPSVQPSLLEDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSVPSVQPSLLEDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 SSSEDALEYYKPSTTLDGTNKLCQFSPVQELSEQTPETSPDKEEASIPKKLQTARPSDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSSEDALEYYKPSTTLDGTNKLCQFSPVQELSEQTPETSPDKEEASIPKKLQTARPSDSQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SKRLHSVRTSSSGTAQRSLLSPLHRSGSVEDNYHTSFLFGLSTSQQHLTKSAGLGLKGWH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKRLHSVRTSSSGTAQRSLLSPLHRSGSVEDNYHTSFLFGLSTSQQHLTKSAGLGLKGWH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SDILAPQTSTPSLTSSWYFATESSHFYSASAIYGGSASYSAYSCSQLPTCGDQVYSVRRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDILAPQTSTPSLTSSWYFATESSHFYSASAIYGGSASYSAYSCSQLPTCGDQVYSVRRR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 QKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSME 610 620 630 640 650 660 pF1KA1 IIEVS ::::: XP_011 IIEVS >>XP_006719218 (OMIM: 607175) PREDICTED: dual specificit (665 aa) initn: 4372 init1: 4372 opt: 4372 Z-score: 3393.9 bits: 638.3 E(85289): 2.7e-182 Smith-Waterman score: 4372; 100.0% identity (100.0% similar) in 665 aa overlap (1-665:1-665) 10 20 30 40 50 60 pF1KA1 MAHEMIGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MAHEMIGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 DKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVHL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKELM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 LVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 QTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRPVHPASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRPVHPASV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 PSVPSVQPSLLEDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PSVPSVQPSLLEDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 SSSEDALEYYKPSTTLDGTNKLCQFSPVQELSEQTPETSPDKEEASIPKKLQTARPSDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSSEDALEYYKPSTTLDGTNKLCQFSPVQELSEQTPETSPDKEEASIPKKLQTARPSDSQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SKRLHSVRTSSSGTAQRSLLSPLHRSGSVEDNYHTSFLFGLSTSQQHLTKSAGLGLKGWH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SKRLHSVRTSSSGTAQRSLLSPLHRSGSVEDNYHTSFLFGLSTSQQHLTKSAGLGLKGWH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SDILAPQTSTPSLTSSWYFATESSHFYSASAIYGGSASYSAYSCSQLPTCGDQVYSVRRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SDILAPQTSTPSLTSSWYFATESSHFYSASAIYGGSASYSAYSCSQLPTCGDQVYSVRRR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 QKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSME 610 620 630 640 650 660 pF1KA1 IIEVS ::::: XP_006 IIEVS >>NP_085143 (OMIM: 607175) dual specificity protein phos (665 aa) initn: 4372 init1: 4372 opt: 4372 Z-score: 3393.9 bits: 638.3 E(85289): 2.7e-182 Smith-Waterman score: 4372; 100.0% identity (100.0% similar) in 665 aa overlap (1-665:1-665) 10 20 30 40 50 60 pF1KA1 MAHEMIGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_085 MAHEMIGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 DKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_085 DKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVHL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_085 LAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKELM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_085 QQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 LVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_085 LVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 QTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRPVHPASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_085 QTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRPVHPASV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 PSVPSVQPSLLEDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_085 PSVPSVQPSLLEDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 SSSEDALEYYKPSTTLDGTNKLCQFSPVQELSEQTPETSPDKEEASIPKKLQTARPSDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_085 SSSEDALEYYKPSTTLDGTNKLCQFSPVQELSEQTPETSPDKEEASIPKKLQTARPSDSQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SKRLHSVRTSSSGTAQRSLLSPLHRSGSVEDNYHTSFLFGLSTSQQHLTKSAGLGLKGWH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_085 SKRLHSVRTSSSGTAQRSLLSPLHRSGSVEDNYHTSFLFGLSTSQQHLTKSAGLGLKGWH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SDILAPQTSTPSLTSSWYFATESSHFYSASAIYGGSASYSAYSCSQLPTCGDQVYSVRRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_085 SDILAPQTSTPSLTSSWYFATESSHFYSASAIYGGSASYSAYSCSQLPTCGDQVYSVRRR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 QKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_085 QKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSME 610 620 630 640 650 660 pF1KA1 IIEVS ::::: NP_085 IIEVS >>XP_005253545 (OMIM: 607175) PREDICTED: dual specificit (517 aa) initn: 3214 init1: 3214 opt: 3214 Z-score: 2499.8 bits: 472.5 E(85289): 1.7e-132 Smith-Waterman score: 3214; 99.8% identity (100.0% similar) in 489 aa overlap (177-665:29-517) 150 160 170 180 190 200 pF1KA1 ISQPCLPVANIGPTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHF .::::::::::::::::::::::::::::: XP_005 MLPLSLQTVFSLYFWVNWRRASTLFTCLQELMQQNGIGYVLNASNTCPKPDFIPESHF 10 20 30 40 50 210 220 230 240 250 260 pF1KA1 LRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMS 60 70 80 90 100 110 270 280 290 300 310 320 pF1KA1 LDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKNQTGASGPKSKLKLLHLEKPNEPVPAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKNQTGASGPKSKLKLLHLEKPNEPVPAV 120 130 140 150 160 170 330 340 350 360 370 380 pF1KA1 SEGGQKSETPLSPPCADSATSEAAGQRPVHPASVPSVPSVQPSLLEDSPLVQALSGLHLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SEGGQKSETPLSPPCADSATSEAAGQRPVHPASVPSVPSVQPSLLEDSPLVQALSGLHLS 180 190 200 210 220 230 390 400 410 420 430 440 pF1KA1 ADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGFSSSEDALEYYKPSTTLDGTNKLCQFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGFSSSEDALEYYKPSTTLDGTNKLCQFS 240 250 260 270 280 290 450 460 470 480 490 500 pF1KA1 PVQELSEQTPETSPDKEEASIPKKLQTARPSDSQSKRLHSVRTSSSGTAQRSLLSPLHRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PVQELSEQTPETSPDKEEASIPKKLQTARPSDSQSKRLHSVRTSSSGTAQRSLLSPLHRS 300 310 320 330 340 350 510 520 530 540 550 560 pF1KA1 GSVEDNYHTSFLFGLSTSQQHLTKSAGLGLKGWHSDILAPQTSTPSLTSSWYFATESSHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSVEDNYHTSFLFGLSTSQQHLTKSAGLGLKGWHSDILAPQTSTPSLTSSWYFATESSHF 360 370 380 390 400 410 570 580 590 600 610 620 pF1KA1 YSASAIYGGSASYSAYSCSQLPTCGDQVYSVRRRQKPSDRADSRRSWHEESPFEKQFKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YSASAIYGGSASYSAYSCSQLPTCGDQVYSVRRRQKPSDRADSRRSWHEESPFEKQFKRR 420 430 440 450 460 470 630 640 650 660 pF1KA1 SCQMEFGESIMSENRSREELGKVGSQSSFSGSMEIIEVS ::::::::::::::::::::::::::::::::::::::: XP_005 SCQMEFGESIMSENRSREELGKVGSQSSFSGSMEIIEVS 480 490 500 510 >>XP_016875477 (OMIM: 607175) PREDICTED: dual specificit (517 aa) initn: 3214 init1: 3214 opt: 3214 Z-score: 2499.8 bits: 472.5 E(85289): 1.7e-132 Smith-Waterman score: 3214; 99.8% identity (100.0% similar) in 489 aa overlap (177-665:29-517) 150 160 170 180 190 200 pF1KA1 ISQPCLPVANIGPTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHF .::::::::::::::::::::::::::::: XP_016 MLPLSLQTVFSLYFWVNWRRASTLFTCLQELMQQNGIGYVLNASNTCPKPDFIPESHF 10 20 30 40 50 210 220 230 240 250 260 pF1KA1 LRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMS 60 70 80 90 100 110 270 280 290 300 310 320 pF1KA1 LDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKNQTGASGPKSKLKLLHLEKPNEPVPAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKNQTGASGPKSKLKLLHLEKPNEPVPAV 120 130 140 150 160 170 330 340 350 360 370 380 pF1KA1 SEGGQKSETPLSPPCADSATSEAAGQRPVHPASVPSVPSVQPSLLEDSPLVQALSGLHLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEGGQKSETPLSPPCADSATSEAAGQRPVHPASVPSVPSVQPSLLEDSPLVQALSGLHLS 180 190 200 210 220 230 390 400 410 420 430 440 pF1KA1 ADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGFSSSEDALEYYKPSTTLDGTNKLCQFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGFSSSEDALEYYKPSTTLDGTNKLCQFS 240 250 260 270 280 290 450 460 470 480 490 500 pF1KA1 PVQELSEQTPETSPDKEEASIPKKLQTARPSDSQSKRLHSVRTSSSGTAQRSLLSPLHRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVQELSEQTPETSPDKEEASIPKKLQTARPSDSQSKRLHSVRTSSSGTAQRSLLSPLHRS 300 310 320 330 340 350 510 520 530 540 550 560 pF1KA1 GSVEDNYHTSFLFGLSTSQQHLTKSAGLGLKGWHSDILAPQTSTPSLTSSWYFATESSHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSVEDNYHTSFLFGLSTSQQHLTKSAGLGLKGWHSDILAPQTSTPSLTSSWYFATESSHF 360 370 380 390 400 410 570 580 590 600 610 620 pF1KA1 YSASAIYGGSASYSAYSCSQLPTCGDQVYSVRRRQKPSDRADSRRSWHEESPFEKQFKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSASAIYGGSASYSAYSCSQLPTCGDQVYSVRRRQKPSDRADSRRSWHEESPFEKQFKRR 420 430 440 450 460 470 630 640 650 660 pF1KA1 SCQMEFGESIMSENRSREELGKVGSQSSFSGSMEIIEVS ::::::::::::::::::::::::::::::::::::::: XP_016 SCQMEFGESIMSENRSREELGKVGSQSSFSGSMEIIEVS 480 490 500 510 >>NP_004411 (OMIM: 602038) dual specificity protein phos (625 aa) initn: 1673 init1: 829 opt: 1483 Z-score: 1159.7 bits: 224.8 E(85289): 7.4e-58 Smith-Waterman score: 1732; 47.0% identity (68.1% similar) in 675 aa overlap (1-665:1-625) 10 20 30 40 50 pF1KA1 MAHEMIGTQIV-TERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQ :: . . ... ...:..::..: :.:::: :::::. :.: ..:: ::::.::::: NP_004 MAGDRLPRKVMDAKKLASLLRGGPGGPLVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA1 QDKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVH : :: :.:::: .:. .:. : :::::::..:.. :..: ::..::.::. :.:: NP_004 QGKVTIAELIQPAARSQVEATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVA 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA1 LLAGGFAEFSRCFPGLCEGK-STLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKE .:.:::: :: ::::::::: ..:.: .::::::: ..: :::::.:::: :.:::::. NP_004 ILTGGFATFSSCFPGLCEGKPAALLPMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKD 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA1 LMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNG :: ::::.:::::::.::::::: ::.:.:::.::..:::.:::::::..::.::: :. NP_004 LMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSC 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA1 CVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKI :.:::::::::::::::::::: : :: :.::::::..::.::::::::::::.::... NP_004 QVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA1 KNQTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRP--VH : .. .: . . : :: :. . :. . : :: ..::.. :. : . NP_004 KLLAALQGDPGTPS----GTP-EPPPSPAAGAPLPRLP--PPTSESAATGNAAAREGGLS 310 320 330 340 350 360 370 380 390 400 410 pF1KA1 PASVPSVPSVQPSLLEDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKSVSYSASMAAS .. : .: . :. : : :.: :::::.:::.:.:.::::::::::: .:. : . NP_004 AGGEPPAPPTPPAT---SALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKS-AYAPSRRPD 360 370 380 390 400 420 430 440 450 460 470 pF1KA1 LHGFSSSEDALEYYKPSTTLDGTNKLCQF-SPV-QELSEQTPETSPDKEEASIPKKLQTA : . .: : :::.. :: :. ..: :::. .:. :. : NP_004 GPGPPDPGEA-----P--------KLCKLDSPSGAALGLSSP--SPDSPDAA-PE----A 410 420 430 440 480 490 500 510 520 530 pF1KA1 RPSDSQSKRLHSVRTSSSGTAQRSLLSPLHRSG-SVEDNYHTSFLFGLSTSQQHLTKSAG :: . : .:. :: : : : . : . . :::. . . : NP_004 RPRPRRRPR------PPAGSPARS---PAHSLGLNFGDAARQTPRHGLSALSAPGLPGPG 450 460 470 480 490 500 540 550 560 570 580 590 pF1KA1 L--GLKGWHSDILAPQTSTPSLTSSWYFATESSHFYSASAIYGGSASYSAYSCSQLPTCG : .: . .: .::: . : :. :. : .:.. .. .. . : : NP_004 QPAGPGAWAPPLDSP--GTPSPDGPWCFSPEG-------AQGAGGVLFAPFGRAGAPGPG 510 520 530 540 550 600 610 620 630 640 650 pF1KA1 DQVYSVRRRQKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSR-EELGKVG ::. .. :.: .: :: : ::::::::::: :. : :.:.: :::. .: NP_004 GGSDLRRREAARAEPRDARTGWPEEPAPETQFKRRSCQMEFEEG-MVEGRARGEELAALG 560 570 580 590 600 610 660 pF1KA1 SQSSFSGSMEIIEVS .:.:::::.:.:::: NP_004 KQASFSGSVEVIEVS 620 >>XP_011518234 (OMIM: 602038) PREDICTED: dual specificit (625 aa) initn: 1673 init1: 829 opt: 1483 Z-score: 1159.7 bits: 224.8 E(85289): 7.4e-58 Smith-Waterman score: 1732; 47.0% identity (68.1% similar) in 675 aa overlap (1-665:1-625) 10 20 30 40 50 pF1KA1 MAHEMIGTQIV-TERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQ :: . . ... ...:..::..: :.:::: :::::. :.: ..:: ::::.::::: XP_011 MAGDRLPRKVMDAKKLASLLRGGPGGPLVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA1 QDKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVH : :: :.:::: .:. .:. : :::::::..:.. :..: ::..::.::. :.:: XP_011 QGKVTIAELIQPAARSQVEATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVA 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA1 LLAGGFAEFSRCFPGLCEGK-STLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKE .:.:::: :: ::::::::: ..:.: .::::::: ..: :::::.:::: :.:::::. XP_011 ILTGGFATFSSCFPGLCEGKPAALLPMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKD 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA1 LMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNG :: ::::.:::::::.::::::: ::.:.:::.::..:::.:::::::..::.::: :. XP_011 LMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSC 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA1 CVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKI :.:::::::::::::::::::: : :: :.::::::..::.::::::::::::.::... XP_011 QVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA1 KNQTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRP--VH : .. .: . . : :: :. . :. . : :: ..::.. :. : . XP_011 KLLAALQGDPGTPS----GTP-EPPPSPAAGAPLPRLP--PPTSESAATGNAAAREGGLS 310 320 330 340 350 360 370 380 390 400 410 pF1KA1 PASVPSVPSVQPSLLEDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKSVSYSASMAAS .. : .: . :. : : :.: :::::.:::.:.:.::::::::::: .:. : . XP_011 AGGEPPAPPTPPAT---SALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKS-AYAPSRRPD 360 370 380 390 400 420 430 440 450 460 470 pF1KA1 LHGFSSSEDALEYYKPSTTLDGTNKLCQF-SPV-QELSEQTPETSPDKEEASIPKKLQTA : . .: : :::.. :: :. ..: :::. .:. :. : XP_011 GPGPPDPGEA-----P--------KLCKLDSPSGAALGLSSP--SPDSPDAA-PE----A 410 420 430 440 480 490 500 510 520 530 pF1KA1 RPSDSQSKRLHSVRTSSSGTAQRSLLSPLHRSG-SVEDNYHTSFLFGLSTSQQHLTKSAG :: . : .:. :: : : : . : . . :::. . . : XP_011 RPRPRRRPR------PPAGSPARS---PAHSLGLNFGDAARQTPRHGLSALSAPGLPGPG 450 460 470 480 490 500 540 550 560 570 580 590 pF1KA1 L--GLKGWHSDILAPQTSTPSLTSSWYFATESSHFYSASAIYGGSASYSAYSCSQLPTCG : .: . .: .::: . : :. :. : .:.. .. .. . : : XP_011 QPAGPGAWAPPLDSP--GTPSPDGPWCFSPEG-------AQGAGGVLFAPFGRAGAPGPG 510 520 530 540 550 600 610 620 630 640 650 pF1KA1 DQVYSVRRRQKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSR-EELGKVG ::. .. :.: .: :: : ::::::::::: :. : :.:.: :::. .: XP_011 GGSDLRRREAARAEPRDARTGWPEEPAPETQFKRRSCQMEFEEG-MVEGRARGEELAALG 560 570 580 590 600 610 660 pF1KA1 SQSSFSGSMEIIEVS .:.:::::.:.:::: XP_011 KQASFSGSVEVIEVS 620 >>XP_011518235 (OMIM: 602038) PREDICTED: dual specificit (625 aa) initn: 1673 init1: 829 opt: 1483 Z-score: 1159.7 bits: 224.8 E(85289): 7.4e-58 Smith-Waterman score: 1732; 47.0% identity (68.1% similar) in 675 aa overlap (1-665:1-625) 10 20 30 40 50 pF1KA1 MAHEMIGTQIV-TERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQ :: . . ... ...:..::..: :.:::: :::::. :.: ..:: ::::.::::: XP_011 MAGDRLPRKVMDAKKLASLLRGGPGGPLVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA1 QDKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVH : :: :.:::: .:. .:. : :::::::..:.. :..: ::..::.::. :.:: XP_011 QGKVTIAELIQPAARSQVEATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVA 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA1 LLAGGFAEFSRCFPGLCEGK-STLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKE .:.:::: :: ::::::::: ..:.: .::::::: ..: :::::.:::: :.:::::. XP_011 ILTGGFATFSSCFPGLCEGKPAALLPMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKD 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA1 LMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNG :: ::::.:::::::.::::::: ::.:.:::.::..:::.:::::::..::.::: :. XP_011 LMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSC 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA1 CVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKI :.:::::::::::::::::::: : :: :.::::::..::.::::::::::::.::... XP_011 QVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA1 KNQTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRP--VH : .. .: . . : :: :. . :. . : :: ..::.. :. : . XP_011 KLLAALQGDPGTPS----GTP-EPPPSPAAGAPLPRLP--PPTSESAATGNAAAREGGLS 310 320 330 340 350 360 370 380 390 400 410 pF1KA1 PASVPSVPSVQPSLLEDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKSVSYSASMAAS .. : .: . :. : : :.: :::::.:::.:.:.::::::::::: .:. : . XP_011 AGGEPPAPPTPPAT---SALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKS-AYAPSRRPD 360 370 380 390 400 420 430 440 450 460 470 pF1KA1 LHGFSSSEDALEYYKPSTTLDGTNKLCQF-SPV-QELSEQTPETSPDKEEASIPKKLQTA : . .: : :::.. :: :. ..: :::. .:. :. : XP_011 GPGPPDPGEA-----P--------KLCKLDSPSGAALGLSSP--SPDSPDAA-PE----A 410 420 430 440 480 490 500 510 520 530 pF1KA1 RPSDSQSKRLHSVRTSSSGTAQRSLLSPLHRSG-SVEDNYHTSFLFGLSTSQQHLTKSAG :: . : .:. :: : : : . : . . :::. . . : XP_011 RPRPRRRPR------PPAGSPARS---PAHSLGLNFGDAARQTPRHGLSALSAPGLPGPG 450 460 470 480 490 500 540 550 560 570 580 590 pF1KA1 L--GLKGWHSDILAPQTSTPSLTSSWYFATESSHFYSASAIYGGSASYSAYSCSQLPTCG : .: . .: .::: . : :. :. : .:.. .. .. . : : XP_011 QPAGPGAWAPPLDSP--GTPSPDGPWCFSPEG-------AQGAGGVLFAPFGRAGAPGPG 510 520 530 540 550 600 610 620 630 640 650 pF1KA1 DQVYSVRRRQKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSR-EELGKVG ::. .. :.: .: :: : ::::::::::: :. : :.:.: :::. .: XP_011 GGSDLRRREAARAEPRDARTGWPEEPAPETQFKRRSCQMEFEEG-MVEGRARGEELAALG 560 570 580 590 600 610 660 pF1KA1 SQSSFSGSMEIIEVS .:.:::::.:.:::: XP_011 KQASFSGSVEVIEVS 620 >>NP_004409 (OMIM: 603068) dual specificity protein phos (314 aa) initn: 543 init1: 312 opt: 473 Z-score: 382.9 bits: 80.1 E(85289): 1.4e-14 Smith-Waterman score: 555; 36.8% identity (62.8% similar) in 288 aa overlap (24-298:25-311) 10 20 30 40 50 pF1KA1 MAHEMIGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQ :..::.: :::. . :. : . . :..:: . NP_004 MGLEAARELECAALGTLLRDPREAERTLLLDCRPFLAFCRRHVRAARPVPWNALLRRRAR 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA1 QDK--VLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVASLSSDC----FLTVLLGKLEK :: : ... . .. ..:: :..: .:: : : .:..:: . . NP_004 GPPAAVLACLLPDRALRTRLVRGELARAVVLDEGSASVAELRPDSPAHVLLAALLHETRA 70 80 90 100 110 120 120 130 140 150 160 pF1KA1 SFNSVHLLAGGFAEFSRCFPGLC-EGKSTLVP-----TCISQPCLPVANIG-PTRILPNL . ..:..: ::: :. : : :: :. . .: : :. :: . : :..::: : NP_004 GPTAVYFLRGGFDGFQGCCPDLCSEAPAPALPPTGDKTSRSDSRAPVYDQGGPVEILPYL 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA1 YLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKS .:: . . .: :: :::.: .::. : .. .::.:. .: :.... NP_004 FLGSCSHSSDLQGLQACGITAVLNVSASCPN-HFEGLFRYKSIPVEDNQMVEISAWFQEA 190 200 210 220 230 230 240 250 260 270 280 pF1KA1 VDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFN . ::. .: :.: ::::: ::::::::: .::.:. . ::::. :::..: .:::::. NP_004 IGFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFS 240 250 260 270 280 290 290 300 310 320 330 340 pF1KA1 FLGQLLDYEKKIKNQTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSAT :.::::..: .. NP_004 FMGQLLQFETQVLCH 300 310 665 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 01:45:05 2016 done: Fri Nov 4 01:45:07 2016 Total Scan time: 11.960 Total Display time: 0.130 Function used was FASTA [36.3.4 Apr, 2011]