FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1708, 1661 aa 1>>>pF1KA1708 1661 - 1661 aa - 1661 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.6383+/-0.000672; mu= -18.5659+/- 0.042 mean_var=687.7744+/-146.120, 0's: 0 Z-trim(118.4): 263 B-trim: 456 in 1/53 Lambda= 0.048905 statistics sampled from 31093 (31357) to 31093 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.368), width: 16 Scan time: 17.960 The best scores are: opt bits E(85289) NP_060111 (OMIM: 135700,608283) kinesin-like prote (1661) 10659 769.4 0 XP_005269067 (OMIM: 135700,608283) PREDICTED: kine (1662) 10647 768.5 0 XP_016875096 (OMIM: 135700,608283) PREDICTED: kine (1657) 10617 766.4 0 XP_006719556 (OMIM: 135700,608283) PREDICTED: kine (1655) 10577 763.6 0 XP_016875097 (OMIM: 135700,608283) PREDICTED: kine (1644) 8149 592.3 1.2e-167 NP_001166934 (OMIM: 135700,608283) kinesin-like pr (1637) 8079 587.3 3.6e-166 XP_016875100 (OMIM: 135700,608283) PREDICTED: kine (1601) 7862 572.0 1.5e-161 XP_016875098 (OMIM: 135700,608283) PREDICTED: kine (1607) 7810 568.3 1.9e-160 XP_005269066 (OMIM: 135700,608283) PREDICTED: kine (1668) 7447 542.7 9.8e-153 NP_001166935 (OMIM: 135700,608283) kinesin-like pr (1674) 7162 522.6 1.1e-146 XP_005269064 (OMIM: 135700,608283) PREDICTED: kine (1675) 7150 521.8 2e-146 XP_005269065 (OMIM: 135700,608283) PREDICTED: kine (1670) 7120 519.7 8.6e-146 NP_001166936 (OMIM: 135700,608283) kinesin-like pr (1621) 5064 374.6 3.9e-102 XP_016875099 (OMIM: 135700,608283) PREDICTED: kine (1607) 4662 346.2 1.3e-93 XP_005269068 (OMIM: 135700,608283) PREDICTED: kine (1657) 4652 345.5 2.2e-93 NP_060066 (OMIM: 608322) kinesin-like protein KIF2 (1624) 4513 335.7 2e-90 NP_001239032 (OMIM: 608322) kinesin-like protein K (1610) 4499 334.7 3.9e-90 XP_005269069 (OMIM: 135700,608283) PREDICTED: kine (1632) 4469 332.6 1.7e-89 NP_001239031 (OMIM: 608322) kinesin-like protein K (1623) 4467 332.5 1.9e-89 NP_001239029 (OMIM: 608322) kinesin-like protein K (1637) 4467 332.5 1.9e-89 XP_006719557 (OMIM: 135700,608283) PREDICTED: kine (1631) 4459 331.9 2.8e-89 XP_005269070 (OMIM: 135700,608283) PREDICTED: kine (1627) 4451 331.4 4.1e-89 XP_005269071 (OMIM: 135700,608283) PREDICTED: kine (1614) 4365 325.3 2.7e-87 XP_011536858 (OMIM: 135700,608283) PREDICTED: kine (1652) 3796 285.1 3.4e-75 XP_016856221 (OMIM: 608322) PREDICTED: kinesin-lik (1236) 2026 160.1 1.1e-37 XP_016856220 (OMIM: 608322) PREDICTED: kinesin-lik (1581) 2026 160.2 1.3e-37 XP_016870394 (OMIM: 611253) PREDICTED: kinesin-lik (1361) 643 62.6 2.7e-08 XP_016870392 (OMIM: 611253) PREDICTED: kinesin-lik (1401) 613 60.5 1.2e-07 NP_060046 (OMIM: 611253) kinesin-like protein KIF2 (1401) 613 60.5 1.2e-07 XP_016870393 (OMIM: 611253) PREDICTED: kinesin-lik (1401) 613 60.5 1.2e-07 XP_016870396 (OMIM: 611253) PREDICTED: kinesin-lik (1335) 604 59.8 1.8e-07 NP_001258856 (OMIM: 611253) kinesin-like protein K (1335) 604 59.8 1.8e-07 XP_016870397 (OMIM: 611253) PREDICTED: kinesin-lik (1304) 602 59.7 2e-07 NP_001258857 (OMIM: 611253) kinesin-like protein K (1304) 602 59.7 2e-07 XP_011517158 (OMIM: 611253) PREDICTED: kinesin-lik (1162) 590 58.8 3.3e-07 XP_016870398 (OMIM: 611253) PREDICTED: kinesin-lik (1275) 590 58.8 3.5e-07 XP_011517152 (OMIM: 611253) PREDICTED: kinesin-lik (1427) 590 58.9 3.8e-07 XP_016870391 (OMIM: 611253) PREDICTED: kinesin-lik (1427) 590 58.9 3.8e-07 XP_016870390 (OMIM: 611253) PREDICTED: kinesin-lik (1427) 590 58.9 3.8e-07 XP_011517150 (OMIM: 611253) PREDICTED: kinesin-lik (1427) 590 58.9 3.8e-07 XP_011517151 (OMIM: 611253) PREDICTED: kinesin-lik (1427) 590 58.9 3.8e-07 XP_016870389 (OMIM: 611253) PREDICTED: kinesin-lik (1427) 590 58.9 3.8e-07 XP_016870403 (OMIM: 611253) PREDICTED: kinesin-lik ( 895) 576 57.7 5.4e-07 XP_016870395 (OMIM: 611253) PREDICTED: kinesin-lik (1355) 582 58.3 5.4e-07 XP_016870399 (OMIM: 611253) PREDICTED: kinesin-lik (1270) 576 57.9 6.9e-07 XP_011517156 (OMIM: 611253) PREDICTED: kinesin-lik (1296) 567 57.2 1.1e-06 NP_004789 (OMIM: 603754) kinesin-like protein KIF3 ( 747) 555 56.2 1.3e-06 XP_005264356 (OMIM: 602845) PREDICTED: kinesin-lik ( 792) 554 56.1 1.4e-06 NP_002245 (OMIM: 602845) kinesin-like protein KIF3 ( 793) 554 56.1 1.4e-06 NP_004512 (OMIM: 602809) kinesin-1 heavy chain [Ho ( 963) 553 56.1 1.7e-06 >>NP_060111 (OMIM: 135700,608283) kinesin-like protein K (1661 aa) initn: 10659 init1: 10659 opt: 10659 Z-score: 4087.9 bits: 769.4 E(85289): 0 Smith-Waterman score: 10659; 100.0% identity (100.0% similar) in 1661 aa overlap (1-1661:1-1661) 10 20 30 40 50 60 pF1KA1 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESIND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESIND 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 MFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 AKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 AKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 EEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 EEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 LKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 RLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 EIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 EIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 SSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRV 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 FISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 FISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 ENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 ENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACT 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 LTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 LTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAEL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 NPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 NPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 RRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 RRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSP 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 PPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 PPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 SSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRSSRRGIINPFPASKGIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRSSRRGIINPFPASKGIR 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA1 AFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 AFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSV 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA1 KYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 KYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQ 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA1 INQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 INQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITG 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA1 SKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQK 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA1 DLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 DLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAIC 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 pF1KA1 VNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN ::::::::::::::::::::::::::::::::::::::::: NP_060 VNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN 1630 1640 1650 1660 >>XP_005269067 (OMIM: 135700,608283) PREDICTED: kinesin- (1662 aa) initn: 8595 init1: 8231 opt: 10647 Z-score: 4083.3 bits: 768.5 E(85289): 0 Smith-Waterman score: 10647; 99.9% identity (99.9% similar) in 1662 aa overlap (1-1661:1-1662) 10 20 30 40 50 60 pF1KA1 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESIND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESIND 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 MFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 AKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 EEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 EIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 SSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRV 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 FISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 ENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACT 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 LTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAEL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 NPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 RRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSP 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 PPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 pF1KA1 SSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVH-RSSRRGIINPFPASKGI :::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::: XP_005 SSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHSRSSRRGIINPFPASKGI 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KA1 RAFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RAFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVS 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KA1 VKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGEN 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KA1 QINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIIT 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KA1 GSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQ 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KA1 KDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAI 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 pF1KA1 CVNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN :::::::::::::::::::::::::::::::::::::::::: XP_005 CVNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN 1630 1640 1650 1660 >>XP_016875096 (OMIM: 135700,608283) PREDICTED: kinesin- (1657 aa) initn: 8270 init1: 8229 opt: 10617 Z-score: 4071.9 bits: 766.4 E(85289): 0 Smith-Waterman score: 10617; 99.8% identity (99.8% similar) in 1661 aa overlap (1-1661:1-1657) 10 20 30 40 50 60 pF1KA1 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESIND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESIND 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 MFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 AKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 EEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 EIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 SSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRV 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 FISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 ENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACT 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 LTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAEL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 NPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 RRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSP 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 PPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 SSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRSSRRGIINPFPASKGIR ::::::::::::::::::::::::::::::::::::::::::: ::::::::::::: XP_016 SSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHR----GIINPFPASKGIR 1270 1280 1290 1300 1310 1330 1340 1350 1360 1370 1380 pF1KA1 AFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSV 1320 1330 1340 1350 1360 1370 1390 1400 1410 1420 1430 1440 pF1KA1 KYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQ 1380 1390 1400 1410 1420 1430 1450 1460 1470 1480 1490 1500 pF1KA1 INQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 INQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITG 1440 1450 1460 1470 1480 1490 1510 1520 1530 1540 1550 1560 pF1KA1 SKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQK 1500 1510 1520 1530 1540 1550 1570 1580 1590 1600 1610 1620 pF1KA1 DLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAIC 1560 1570 1580 1590 1600 1610 1630 1640 1650 1660 pF1KA1 VNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN ::::::::::::::::::::::::::::::::::::::::: XP_016 VNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN 1620 1630 1640 1650 >>XP_006719556 (OMIM: 135700,608283) PREDICTED: kinesin- (1655 aa) initn: 9636 init1: 6890 opt: 10577 Z-score: 4056.6 bits: 763.6 E(85289): 0 Smith-Waterman score: 10577; 99.5% identity (99.5% similar) in 1662 aa overlap (1-1661:1-1655) 10 20 30 40 50 60 pF1KA1 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESIND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESIND 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 MFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 AKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 EEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 EIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 SSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRV 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 FISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 ENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACT 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 LTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAEL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 NPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKA ::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_006 NPELDALLGHALQ-------ENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKA 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 pF1KA1 RRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSP 1140 1150 1160 1170 1180 1190 1210 1220 1230 1240 1250 1260 pF1KA1 PPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPP 1200 1210 1220 1230 1240 1250 1270 1280 1290 1300 1310 pF1KA1 SSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVH-RSSRRGIINPFPASKGI :::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::: XP_006 SSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHSRSSRRGIINPFPASKGI 1260 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 pF1KA1 RAFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RAFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVS 1320 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 pF1KA1 VKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGEN 1380 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 pF1KA1 QINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIIT 1440 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 pF1KA1 GSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQ 1500 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 pF1KA1 KDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAI 1560 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 pF1KA1 CVNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN :::::::::::::::::::::::::::::::::::::::::: XP_006 CVNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN 1620 1630 1640 1650 >>XP_016875097 (OMIM: 135700,608283) PREDICTED: kinesin- (1644 aa) initn: 8190 init1: 8149 opt: 8149 Z-score: 3130.8 bits: 592.3 E(85289): 1.2e-167 Smith-Waterman score: 10511; 99.0% identity (99.0% similar) in 1661 aa overlap (1-1661:1-1644) 10 20 30 40 50 60 pF1KA1 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESIND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESIND 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 MFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 AKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 EEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 EIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 SSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRV 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 FISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 ENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACT 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 LTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAEL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 NPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 RRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSP 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 PPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 SSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRSSRRGIINPFPASKGIR :::::::::::::::::::::::::::::: ::::::::::::: XP_016 SSPPSRPRNELNVFNRLTVSQGNTSVQQDK-----------------GIINPFPASKGIR 1270 1280 1290 1300 1330 1340 1350 1360 1370 1380 pF1KA1 AFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSV 1310 1320 1330 1340 1350 1360 1390 1400 1410 1420 1430 1440 pF1KA1 KYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQ 1370 1380 1390 1400 1410 1420 1450 1460 1470 1480 1490 1500 pF1KA1 INQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 INQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITG 1430 1440 1450 1460 1470 1480 1510 1520 1530 1540 1550 1560 pF1KA1 SKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQK 1490 1500 1510 1520 1530 1540 1570 1580 1590 1600 1610 1620 pF1KA1 DLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAIC 1550 1560 1570 1580 1590 1600 1630 1640 1650 1660 pF1KA1 VNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN ::::::::::::::::::::::::::::::::::::::::: XP_016 VNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN 1610 1620 1630 1640 >>NP_001166934 (OMIM: 135700,608283) kinesin-like protei (1637 aa) initn: 9285 init1: 6890 opt: 8079 Z-score: 3104.2 bits: 587.3 E(85289): 3.6e-166 Smith-Waterman score: 10441; 98.6% identity (98.6% similar) in 1661 aa overlap (1-1661:1-1637) 10 20 30 40 50 60 pF1KA1 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESIND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESIND 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 MFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 AKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 EEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 EIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 SSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRV 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 FISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 ENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACT 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 LTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAEL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 NPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKA ::::::::::::: :::::::::::::::::::::::::::::::::::::::: NP_001 NPELDALLGHALQ-------ENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKA 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 pF1KA1 RRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSP 1140 1150 1160 1170 1180 1190 1210 1220 1230 1240 1250 1260 pF1KA1 PPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPP 1200 1210 1220 1230 1240 1250 1270 1280 1290 1300 1310 1320 pF1KA1 SSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRSSRRGIINPFPASKGIR :::::::::::::::::::::::::::::: ::::::::::::: NP_001 SSPPSRPRNELNVFNRLTVSQGNTSVQQDK-----------------GIINPFPASKGIR 1260 1270 1280 1290 1330 1340 1350 1360 1370 1380 pF1KA1 AFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSV 1300 1310 1320 1330 1340 1350 1390 1400 1410 1420 1430 1440 pF1KA1 KYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQ 1360 1370 1380 1390 1400 1410 1450 1460 1470 1480 1490 1500 pF1KA1 INQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 INQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITG 1420 1430 1440 1450 1460 1470 1510 1520 1530 1540 1550 1560 pF1KA1 SKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQK 1480 1490 1500 1510 1520 1530 1570 1580 1590 1600 1610 1620 pF1KA1 DLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAIC 1540 1550 1560 1570 1580 1590 1630 1640 1650 1660 pF1KA1 VNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN ::::::::::::::::::::::::::::::::::::::::: NP_001 VNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN 1600 1610 1620 1630 >>XP_016875100 (OMIM: 135700,608283) PREDICTED: kinesin- (1601 aa) initn: 7903 init1: 7862 opt: 7862 Z-score: 3021.5 bits: 572.0 E(85289): 1.5e-161 Smith-Waterman score: 10138; 96.3% identity (96.4% similar) in 1661 aa overlap (1-1661:1-1601) 10 20 30 40 50 60 pF1KA1 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESIND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESIND 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 MFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 AKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 EEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 EIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 SSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRV 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 FISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 ENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACT 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 LTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAEL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 NPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 RRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSP 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 PPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPP ::::::::::::::::::::::::::::::::::::::::::::::. XP_016 PPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKQ------------- 1210 1220 1230 1240 1270 1280 1290 1300 1310 1320 pF1KA1 SSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRSSRRGIINPFPASKGIR ::::::::::::: XP_016 -----------------------------------------------GIINPFPASKGIR 1250 1260 1330 1340 1350 1360 1370 1380 pF1KA1 AFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSV 1270 1280 1290 1300 1310 1320 1390 1400 1410 1420 1430 1440 pF1KA1 KYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQ 1330 1340 1350 1360 1370 1380 1450 1460 1470 1480 1490 1500 pF1KA1 INQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 INQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITG 1390 1400 1410 1420 1430 1440 1510 1520 1530 1540 1550 1560 pF1KA1 SKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQK 1450 1460 1470 1480 1490 1500 1570 1580 1590 1600 1610 1620 pF1KA1 DLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAIC 1510 1520 1530 1540 1550 1560 1630 1640 1650 1660 pF1KA1 VNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN ::::::::::::::::::::::::::::::::::::::::: XP_016 VNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN 1570 1580 1590 1600 >>XP_016875098 (OMIM: 135700,608283) PREDICTED: kinesin- (1607 aa) initn: 10544 init1: 6890 opt: 7810 Z-score: 3001.7 bits: 568.3 E(85289): 1.9e-160 Smith-Waterman score: 10165; 96.7% identity (96.7% similar) in 1661 aa overlap (1-1661:1-1607) 10 20 30 40 50 60 pF1KA1 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESIND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESIND 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 MFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 AKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 EEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 EIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 SSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRV 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 FISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 ENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACT 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 LTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAEL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 NPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKA ::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_016 NPELDALLGHALQ-------ENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKA 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 pF1KA1 RRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSP 1140 1150 1160 1170 1180 1190 1210 1220 1230 1240 1250 1260 pF1KA1 PPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPP :::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQK-------------- 1200 1210 1220 1230 1270 1280 1290 1300 1310 1320 pF1KA1 SSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRSSRRGIINPFPASKGIR .::::::::::::: ::::::::::::: XP_016 -----------------------------QSDESDSSLSEVHR----GIINPFPASKGIR 1240 1250 1260 1330 1340 1350 1360 1370 1380 pF1KA1 AFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSV 1270 1280 1290 1300 1310 1320 1390 1400 1410 1420 1430 1440 pF1KA1 KYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQ 1330 1340 1350 1360 1370 1380 1450 1460 1470 1480 1490 1500 pF1KA1 INQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 INQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITG 1390 1400 1410 1420 1430 1440 1510 1520 1530 1540 1550 1560 pF1KA1 SKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQK 1450 1460 1470 1480 1490 1500 1570 1580 1590 1600 1610 1620 pF1KA1 DLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAIC 1510 1520 1530 1540 1550 1560 1630 1640 1650 1660 pF1KA1 VNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN ::::::::::::::::::::::::::::::::::::::::: XP_016 VNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN 1570 1580 1590 1600 >>XP_005269066 (OMIM: 135700,608283) PREDICTED: kinesin- (1668 aa) initn: 9532 init1: 3585 opt: 7447 Z-score: 2863.1 bits: 542.7 E(85289): 9.8e-153 Smith-Waterman score: 10541; 98.7% identity (98.7% similar) in 1675 aa overlap (1-1661:1-1668) 10 20 30 40 50 60 pF1KA1 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESIND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESIND 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 MFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL 490 500 510 520 530 540 550 560 570 580 pF1KA1 AKKDLEKLKRKEKRKKK-------------SVAGKEDNTDTDQEKKEEKGVSERENNELE ::::::::::::::::: :::::::::::::::::::::::::::::: XP_005 AKKDLEKLKRKEKRKKKRLQKLEESNREERSVAGKEDNTDTDQEKKEEKGVSERENNELE 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA1 VEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKL 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA1 IDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSE 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA1 YEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEE 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA1 QEKARLTESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QEKARLTESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPM 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA1 SDKVAGKVTRKLSSSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDKVAGKVTRKLSSSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGN 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA1 RKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKR 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA1 REKLSKRREKIVKENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 REKLSKRREKIVKENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEG 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KA1 ETLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ETLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQN 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KA1 QLLFHMLKEKAELNPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDL :::::::::::::::::::::::::: ::::::::::::::::::::::::::: XP_005 QLLFHMLKEKAELNPELDALLGHALQ-------ENVEDSTDEDAPLNSPGSEGSTLSSDL 1090 1100 1110 1120 1130 1130 1140 1150 1160 1170 1180 pF1KA1 MKLCGEVKPKNKARRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKLCGEVKPKNKARRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTE 1140 1150 1160 1170 1180 1190 1190 1200 1210 1220 1230 1240 pF1KA1 TSGTSAREKELSPPPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSGTSAREKELSPPPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKH 1200 1210 1220 1230 1240 1250 1250 1260 1270 1280 1290 1300 pF1KA1 SDSGTSEASLSPPSSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVH-RSSR ::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::: XP_005 SDSGTSEASLSPPSSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHSRSSR 1260 1270 1280 1290 1300 1310 1310 1320 1330 1340 1350 1360 pF1KA1 RGIINPFPASKGIRAFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RGIINPFPASKGIRAFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQE 1320 1330 1340 1350 1360 1370 1370 1380 1390 1400 1410 1420 pF1KA1 IMSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IMSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSA 1380 1390 1400 1410 1420 1430 1430 1440 1450 1460 1470 1480 pF1KA1 STSRTVAIPSGENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 STSRTVAIPSGENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLT 1440 1450 1460 1470 1480 1490 1490 1500 1510 1520 1530 1540 pF1KA1 VDQISSGQDLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VDQISSGQDLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSG 1500 1510 1520 1530 1540 1550 1550 1560 1570 1580 1590 1600 pF1KA1 SRDNGIKKWDLTQKDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SRDNGIKKWDLTQKDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPV 1560 1570 1580 1590 1600 1610 1610 1620 1630 1640 1650 1660 pF1KA1 GEMKGHDSPINAICVNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GEMKGHDSPINAICVNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN 1620 1630 1640 1650 1660 >>NP_001166935 (OMIM: 135700,608283) kinesin-like protei (1674 aa) initn: 7132 init1: 7132 opt: 7162 Z-score: 2754.4 bits: 522.6 E(85289): 1.1e-146 Smith-Waterman score: 10623; 99.2% identity (99.2% similar) in 1674 aa overlap (1-1661:1-1674) 10 20 30 40 50 60 pF1KA1 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESIND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESIND 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 MFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL 490 500 510 520 530 540 550 560 570 580 pF1KA1 AKKDLEKLKRKEKRKKK-------------SVAGKEDNTDTDQEKKEEKGVSERENNELE ::::::::::::::::: :::::::::::::::::::::::::::::: NP_001 AKKDLEKLKRKEKRKKKRLQKLEESNREERSVAGKEDNTDTDQEKKEEKGVSERENNELE 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA1 VEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKL 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA1 IDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSE 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA1 YEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEE 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA1 QEKARLTESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEKARLTESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPM 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA1 SDKVAGKVTRKLSSSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDKVAGKVTRKLSSSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGN 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA1 RKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKR 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA1 REKLSKRREKIVKENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REKLSKRREKIVKENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEG 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KA1 ETLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQN 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KA1 QLLFHMLKEKAELNPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLLFHMLKEKAELNPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDL 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 1180 pF1KA1 MKLCGEVKPKNKARRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKLCGEVKPKNKARRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTE 1150 1160 1170 1180 1190 1200 1190 1200 1210 1220 1230 1240 pF1KA1 TSGTSAREKELSPPPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSGTSAREKELSPPPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKH 1210 1220 1230 1240 1250 1260 1250 1260 1270 1280 1290 1300 pF1KA1 SDSGTSEASLSPPSSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRSSRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDSGTSEASLSPPSSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRSSRR 1270 1280 1290 1300 1310 1320 1310 1320 1330 1340 1350 1360 pF1KA1 GIINPFPASKGIRAFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GIINPFPASKGIRAFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEI 1330 1340 1350 1360 1370 1380 1370 1380 1390 1400 1410 1420 pF1KA1 MSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSAS 1390 1400 1410 1420 1430 1440 1430 1440 1450 1460 1470 1480 pF1KA1 TSRTVAIPSGENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSRTVAIPSGENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTV 1450 1460 1470 1480 1490 1500 1490 1500 1510 1520 1530 1540 pF1KA1 DQISSGQDLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DQISSGQDLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGS 1510 1520 1530 1540 1550 1560 1550 1560 1570 1580 1590 1600 pF1KA1 RDNGIKKWDLTQKDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDNGIKKWDLTQKDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVG 1570 1580 1590 1600 1610 1620 1610 1620 1630 1640 1650 1660 pF1KA1 EMKGHDSPINAICVNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EMKGHDSPINAICVNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN 1630 1640 1650 1660 1670 1661 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 21:53:32 2016 done: Wed Nov 2 21:53:35 2016 Total Scan time: 17.960 Total Display time: 0.870 Function used was FASTA [36.3.4 Apr, 2011]