Result of FASTA (omim) for
pF1KA1732
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1732, 2642 aa
1>>>pF1KA1732 2642 - 2642 aa - 2642 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.6031+/-0.000527; mu= -17.4058+/- 0.033
mean_var=535.2817+/-110.074, 0's: 0 Z-trim(121.1): 58 B-trim: 1843 in 1/57
Lambda= 0.055435
statistics sampled from 37102 (37182) to 37102 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.717), E-opt: 0.2 (0.436), width: 16
Scan time: 27.560
The best scores are: opt bits E(85289)
NP_054878 (OMIM: 612778,616831) histone-lysine N-m (2564) 10784 879.4 0
XP_011531934 (OMIM: 612778,616831) PREDICTED: hist (2572) 10758 877.3 0
XP_011531935 (OMIM: 612778,616831) PREDICTED: hist (2545) 10606 865.2 0
XP_011531933 (OMIM: 612778,616831) PREDICTED: hist (2590) 10606 865.2 0
XP_011531936 (OMIM: 612778,616831) PREDICTED: hist (2520) 10467 854.0 0
XP_016861759 (OMIM: 612778,616831) PREDICTED: hist (2490) 10341 844.0 0
NP_001308207 (OMIM: 608753,612389) tRNA-splicing e ( 516) 402 48.7 0.00026
NP_001287848 (OMIM: 150699,600698) high mobility g ( 147) 383 46.8 0.00027
NP_001304977 (OMIM: 616380) laminin subunit beta-4 ( 772) 394 48.1 0.00057
XP_016864077 (OMIM: 194190,602952) PREDICTED: hist ( 584) 381 47.0 0.00093
XP_016864076 (OMIM: 194190,602952) PREDICTED: hist ( 584) 381 47.0 0.00093
XP_011511862 (OMIM: 194190,602952) PREDICTED: hist ( 584) 381 47.0 0.00093
XP_016856700 (OMIM: 147522) PREDICTED: inositol-tr ( 730) 379 46.9 0.0012
XP_005248059 (OMIM: 194190,602952) PREDICTED: hist (1296) 381 47.2 0.0018
XP_005248058 (OMIM: 194190,602952) PREDICTED: hist (1365) 381 47.2 0.0018
XP_011511859 (OMIM: 194190,602952) PREDICTED: hist (1365) 381 47.2 0.0018
NP_579877 (OMIM: 194190,602952) histone-lysine N-m (1365) 381 47.2 0.0018
NP_579878 (OMIM: 194190,602952) histone-lysine N-m (1365) 381 47.2 0.0018
NP_001035889 (OMIM: 194190,602952) histone-lysine (1365) 381 47.2 0.0018
NP_579890 (OMIM: 194190,602952) histone-lysine N-m (1365) 381 47.2 0.0018
NP_001158312 (OMIM: 613311,615595) LYR motif-conta ( 130) 323 42.0 0.0068
XP_016876039 (OMIM: 189969) PREDICTED: general tra ( 193) 327 42.4 0.0076
NP_075447 (OMIM: 607083) histone-lysine N-methyltr (1437) 356 45.3 0.0077
>>NP_054878 (OMIM: 612778,616831) histone-lysine N-methy (2564 aa)
initn: 10784 init1: 10784 opt: 10784 Z-score: 4675.6 bits: 879.4 E(85289): 0
Smith-Waterman score: 17020; 97.0% identity (97.0% similar) in 2642 aa overlap (1-2642:1-2564)
10 20 30 40 50 60
pF1KA1 MKQLQPQPPPKMGDFYDPEHPTPEEEENEAKIENVQKTGFIKGPMFKGVASSRFLPKGTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 MKQLQPQPPPKMGDFYDPEHPTPEEEENEAKIENVQKTGFIKGPMFKGVASSRFLPKGTK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 TKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQVDSTPKMKMEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 TKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQVDSTPKMKMEI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 GDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTHAAPLPAVIAES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 GDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTHAAPLPAVIAES
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 TTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPLPVDVAVRSLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 TTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPLPVDVAVRSLKE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 PPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKDEEIPDSSKISL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 PPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKDEEIPDSSKISL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 SCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 SCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 EDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRSERGSRTNLSYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 EDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRSERGSRTNLSYS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 RSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRTSSHSSSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 RSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRTSSHSSSY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 RDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKRCCSPPNELGFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 RDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKRCCSPPNELGFR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 RGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFSLQTPCSKGSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 RGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFSLQTPCSKGSEL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 RMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSIKELDSLSKVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 RMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSIKELDSLSKVKN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 DQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSPLVKACMLSSNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 DQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSPLVKACMLSSNG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 FQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVDYSKTVVKEPVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 FQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVDYSKTVVKEPVD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 TRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHLESKPVICDSRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 TRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHLESKPVICDSRN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 LTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPGIKVDSLTLLKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 LTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPGIKVDSLTLLKC
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 GENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENRRNNGLSGKCLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 GENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENRRNNGLSGKCLQ
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA1 EAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDGVTYALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 EAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDGVTYALK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA1 CDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSVVVVPKNSTLPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 CDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSVVVVPKNSTLPM
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA1 EETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTDKFFLHKGTEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 EETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTDKFFLHKGTEKN
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA1 PEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEETVKAKIPSRQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 PEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEETVKAKIPSRQQE
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA1 ELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGLHSSEELRNLGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 ELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGLHSSEELRNLGW
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA1 DFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPRSGRPPGTGVVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 DFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPRSGRPPGTGVVY
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA1 DRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQAPEISSNSIKDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 DRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQAPEISSNSIKDT
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA1 LAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRVEVEQGETSVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 LAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRVEVEQGETSVPP
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA1 GSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 GSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCE
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA1 CTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 CTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKK
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA1 GWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDETESRSIA
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 GWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDE-------
1570 1580 1590 1600 1610
1630 1640 1650 1660 1670 1680
pF1KA1 QAGVQWQDLGSLQPLPPGFKRFSCLSFLSSWDYRRPPPRLANFCIFSRDGVSPRWPGWSR
NP_054 ------------------------------------------------------------
1690 1700 1710 1720 1730 1740
pF1KA1 SPDLTKALRLQIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSEL
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 -----------IIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSEL
1620 1630 1640 1650 1660
1750 1760 1770 1780 1790 1800
pF1KA1 TFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRKKDSVDGELEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 TFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRKKDSVDGELEAL
1670 1680 1690 1700 1710 1720
1810 1820 1830 1840 1850 1860
pF1KA1 MENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 MENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIW
1730 1740 1750 1760 1770 1780
1870 1880 1890 1900 1910 1920
pF1KA1 MAELGDGRESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 MAELGDGRESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDG
1790 1800 1810 1820 1830 1840
1930 1940 1950 1960 1970 1980
pF1KA1 YSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFRRLKIISENSMDSAISDATSELEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 YSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFRRLKIISENSMDSAISDATSELEG
1850 1860 1870 1880 1890 1900
1990 2000 2010 2020 2030 2040
pF1KA1 KDGKEDLDQLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 KDGKEDLDQLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEP
1910 1920 1930 1940 1950 1960
2050 2060 2070 2080 2090 2100
pF1KA1 KESNGTKLEEPINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 KESNGTKLEEPINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEV
1970 1980 1990 2000 2010 2020
2110 2120 2130 2140 2150 2160
pF1KA1 YRIPKKSQTEKENTTTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQNKEKRKRRSSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 YRIPKKSQTEKENTTTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQNKEKRKRRSSLS
2030 2040 2050 2060 2070 2080
2170 2180 2190 2200 2210 2220
pF1KA1 PPSSAYERGTKRPDDRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQQQMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 PPSSAYERGTKRPDDRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQQQMQ
2090 2100 2110 2120 2130 2140
2230 2240 2250 2260 2270 2280
pF1KA1 NLGMTSPLPYDSLGYNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 NLGMTSPLPYDSLGYNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAP
2150 2160 2170 2180 2190 2200
2290 2300 2310 2320 2330 2340
pF1KA1 YDHAQPLVGHSTEPLSAPPPVPVVPHVAAPVEVSSSQYVAQSDGVVHQDSSVAVLPVPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 YDHAQPLVGHSTEPLSAPPPVPVVPHVAAPVEVSSSQYVAQSDGVVHQDSSVAVLPVPAP
2210 2220 2230 2240 2250 2260
2350 2360 2370 2380 2390 2400
pF1KA1 GPVQGQNYSVWDSNQQSVSVQQQYSPAQSQATIYYQGQTCPTVYGVTSPYSQTTPPIVQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 GPVQGQNYSVWDSNQQSVSVQQQYSPAQSQATIYYQGQTCPTVYGVTSPYSQTTPPIVQS
2270 2280 2290 2300 2310 2320
2410 2420 2430 2440 2450 2460
pF1KA1 YAQPSLQYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNNLLDLPPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 YAQPSLQYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNNLLDLPPPS
2330 2340 2350 2360 2370 2380
2470 2480 2490 2500 2510 2520
pF1KA1 PPKPKTIVLPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 PPKPKTIVLPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTP
2390 2400 2410 2420 2430 2440
2530 2540 2550 2560 2570 2580
pF1KA1 TYDENPMKASKKPKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 TYDENPMKASKKPKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTT
2450 2460 2470 2480 2490 2500
2590 2600 2610 2620 2630 2640
pF1KA1 EDFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 EDFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTE
2510 2520 2530 2540 2550 2560
pF1KA1 LE
::
NP_054 LE
>>XP_011531934 (OMIM: 612778,616831) PREDICTED: histone- (2572 aa)
initn: 10770 init1: 10595 opt: 10758 Z-score: 4664.3 bits: 877.3 E(85289): 0
Smith-Waterman score: 16994; 96.8% identity (96.8% similar) in 2650 aa overlap (1-2642:1-2572)
10 20 30 40 50
pF1KA1 MKQLQPQPPPKMGDFYDPEHPTPE--------EEENEAKIENVQKTGFIKGPMFKGVASS
:::::::::::::::::::::::: ::::::::::::::::::::::::::::
XP_011 MKQLQPQPPPKMGDFYDPEHPTPEFSWLNGNREEENEAKIENVQKTGFIKGPMFKGVASS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA1 RFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQVDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQVDS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA1 TPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTHAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTHAAP
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA1 LPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPLPVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPLPVD
190 200 210 220 230 240
240 250 260 270 280 290
pF1KA1 VAVRSLKEPPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKDEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAVRSLKEPPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKDEEI
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA1 PDSSKISLSCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDSSKISLSCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 KSSAPLKSEDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRSERG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSSAPLKSEDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRSERG
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 SRTNLSYSRSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRTNLSYSRSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRR
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 TSSHSSSYRDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKRCCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSSHSSSYRDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKRCCS
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 PPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFSLQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFSLQT
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 PCSKGSELRMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSIKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCSKGSELRMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSIKEL
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 DSLSKVKNDQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSPLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSLSKVKNDQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSPLVK
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 ACMLSSNGFQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVDYSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACMLSSNGFQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVDYSK
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA1 TVVKEPVDTRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHLESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVVKEPVDTRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHLESK
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA1 PVICDSRNLTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPGIKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVICDSRNLTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPGIKV
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA1 DSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENRRNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENRRNN
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA1 GLSGKCLQEAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLSGKCLQEAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDS
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA1 DGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSVVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSVVVV
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KA1 PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTDKFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTDKFF
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KA1 LHKGTEKNPEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEETVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHKGTEKNPEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEETVKA
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KA1 KIPSRQQEELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGLHSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIPSRQQEELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGLHSS
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KA1 EELRNLGWDFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPRSGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELRNLGWDFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPRSGR
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KA1 PPGTGVVYDRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQAPEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPGTGVVYDRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQAPEI
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KA1 SSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRVEVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRVEVE
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KA1 QGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHR
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KA1 DIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADV
1510 1520 1530 1540 1550 1560
1560 1570 1580 1590 1600 1610
pF1KA1 EVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKND
1570 1580 1590 1600 1610 1620
1620 1630 1640 1650 1660 1670
pF1KA1 ETESRSIAQAGVQWQDLGSLQPLPPGFKRFSCLSFLSSWDYRRPPPRLANFCIFSRDGVS
:
XP_011 E-----------------------------------------------------------
1680 1690 1700 1710 1720 1730
pF1KA1 PRWPGWSRSPDLTKALRLQIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTK
:::::::::::::::::::::::::::::::::::::::::
XP_011 -------------------IIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTK
1630 1640 1650 1660
1740 1750 1760 1770 1780 1790
pF1KA1 LVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRKKDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRKKDS
1670 1680 1690 1700 1710 1720
1800 1810 1820 1830 1840 1850
pF1KA1 VDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFLERH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFLERH
1730 1740 1750 1760 1770 1780
1860 1870 1880 1890 1900 1910
pF1KA1 GLSLLWIWMAELGDGRESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLSLLWIWMAELGDGRESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAV
1790 1800 1810 1820 1830 1840
1920 1930 1940 1950 1960 1970
pF1KA1 PPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFRRLKIISENSMDSAIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFRRLKIISENSMDSAIS
1850 1860 1870 1880 1890 1900
1980 1990 2000 2010 2020 2030
pF1KA1 DATSELEGKDGKEDLDQLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPTSEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DATSELEGKDGKEDLDQLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPTSEP
1910 1920 1930 1940 1950 1960
2040 2050 2060 2070 2080 2090
pF1KA1 EADAEIEPKESNGTKLEEPINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATKLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EADAEIEPKESNGTKLEEPINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATKLLD
1970 1980 1990 2000 2010 2020
2100 2110 2120 2130 2140 2150
pF1KA1 SWKDLKEVYRIPKKSQTEKENTTTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQNKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWKDLKEVYRIPKKSQTEKENTTTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQNKEK
2030 2040 2050 2060 2070 2080
2160 2170 2180 2190 2200 2210
pF1KA1 RKRRSSLSPPSSAYERGTKRPDDRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQREA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKRRSSLSPPSSAYERGTKRPDDRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQREA
2090 2100 2110 2120 2130 2140
2220 2230 2240 2250 2260 2270
pF1KA1 QKQQQQMQNLGMTSPLPYDSLGYNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKQQQQMQNLGMTSPLPYDSLGYNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSM
2150 2160 2170 2180 2190 2200
2280 2290 2300 2310 2320 2330
pF1KA1 DPVCSPAPYDHAQPLVGHSTEPLSAPPPVPVVPHVAAPVEVSSSQYVAQSDGVVHQDSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPVCSPAPYDHAQPLVGHSTEPLSAPPPVPVVPHVAAPVEVSSSQYVAQSDGVVHQDSSV
2210 2220 2230 2240 2250 2260
2340 2350 2360 2370 2380 2390
pF1KA1 AVLPVPAPGPVQGQNYSVWDSNQQSVSVQQQYSPAQSQATIYYQGQTCPTVYGVTSPYSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVLPVPAPGPVQGQNYSVWDSNQQSVSVQQQYSPAQSQATIYYQGQTCPTVYGVTSPYSQ
2270 2280 2290 2300 2310 2320
2400 2410 2420 2430 2440 2450
pF1KA1 TTPPIVQSYAQPSLQYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTPPIVQSYAQPSLQYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNN
2330 2340 2350 2360 2370 2380
2460 2470 2480 2490 2500 2510
pF1KA1 LLDLPPPSPPKPKTIVLPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASLEHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLDLPPPSPPKPKTIVLPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASLEHE
2390 2400 2410 2420 2430 2440
2520 2530 2540 2550 2560 2570
pF1KA1 AEMDLGTPTYDENPMKASKKPKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEMDLGTPTYDENPMKASKKPKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDC
2450 2460 2470 2480 2490 2500
2580 2590 2600 2610 2620 2630
pF1KA1 KVGRITTTEDFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVGRITTTEDFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAV
2510 2520 2530 2540 2550 2560
2640
pF1KA1 YKPKEDTELE
::::::::::
XP_011 YKPKEDTELE
2570
>>XP_011531935 (OMIM: 612778,616831) PREDICTED: histone- (2545 aa)
initn: 16012 init1: 10606 opt: 10606 Z-score: 4598.7 bits: 865.2 E(85289): 0
Smith-Waterman score: 16467; 95.2% identity (95.2% similar) in 2623 aa overlap (20-2642:46-2545)
10 20 30 40
pF1KA1 MKQLQPQPPPKMGDFYDPEHPTPEEEENEAKIENVQKTGFIKGPMFKGV
.: .:::::::::::::::::::::::::
XP_011 LLLASFCLTPYIQEAELFEGRDAALFKFGLQPLAQEEENEAKIENVQKTGFIKGPMFKGV
20 30 40 50 60 70
50 60 70 80 90 100
pF1KA1 ASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQ
80 90 100 110 120 130
110 120 130 140 150 160
pF1KA1 VDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTH
140 150 160 170 180 190
170 180 190 200 210 220
pF1KA1 AAPLPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAPLPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPL
200 210 220 230 240 250
230 240 250 260 270 280
pF1KA1 PVDVAVRSLKEPPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVDVAVRSLKEPPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKD
260 270 280 290 300 310
290 300 310 320 330 340
pF1KA1 EEIPDSSKISLSCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEIPDSSKISLSCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKER
320 330 340 350 360 370
350 360 370 380 390 400
pF1KA1 DFKKSSAPLKSEDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFKKSSAPLKSEDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRS
380 390 400 410 420 430
410 420 430 440 450 460
pF1KA1 ERGSRTNLSYSRSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERGSRTNLSYSRSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTY
440 450 460 470 480 490
470 480 490 500 510 520
pF1KA1 SRRTSSHSSSYRDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRRTSSHSSSYRDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKR
500 510 520 530 540 550
530 540 550 560 570 580
pF1KA1 CCSPPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CCSPPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFS
560 570 580 590 600 610
590 600 610 620 630 640
pF1KA1 LQTPCSKGSELRMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQTPCSKGSELRMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSI
620 630 640 650 660 670
650 660 670 680 690 700
pF1KA1 KELDSLSKVKNDQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KELDSLSKVKNDQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSP
680 690 700 710 720 730
710 720 730 740 750 760
pF1KA1 LVKACMLSSNGFQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVKACMLSSNGFQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVD
740 750 760 770 780 790
770 780 790 800 810 820
pF1KA1 YSKTVVKEPVDTRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSKTVVKEPVDTRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHL
800 810 820 830 840 850
830 840 850 860 870 880
pF1KA1 ESKPVICDSRNLTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESKPVICDSRNLTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPG
860 870 880 890 900 910
890 900 910 920 930 940
pF1KA1 IKVDSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKVDSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENR
920 930 940 950 960 970
950 960 970 980 990 1000
pF1KA1 RNNGLSGKCLQEAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNNGLSGKCLQEAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTM
980 990 1000 1010 1020 1030
1010 1020 1030 1040 1050 1060
pF1KA1 EDSDGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDSDGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSV
1040 1050 1060 1070 1080 1090
1070 1080 1090 1100 1110 1120
pF1KA1 VVVPKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVVPKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTD
1100 1110 1120 1130 1140 1150
1130 1140 1150 1160 1170 1180
pF1KA1 KFFLHKGTEKNPEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFFLHKGTEKNPEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEET
1160 1170 1180 1190 1200 1210
1190 1200 1210 1220 1230 1240
pF1KA1 VKAKIPSRQQEELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKAKIPSRQQEELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGL
1220 1230 1240 1250 1260 1270
1250 1260 1270 1280 1290 1300
pF1KA1 HSSEELRNLGWDFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSSEELRNLGWDFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPR
1280 1290 1300 1310 1320 1330
1310 1320 1330 1340 1350 1360
pF1KA1 SGRPPGTGVVYDRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGRPPGTGVVYDRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQA
1340 1350 1360 1370 1380 1390
1370 1380 1390 1400 1410 1420
pF1KA1 PEISSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEISSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRV
1400 1410 1420 1430 1440 1450
1430 1440 1450 1460 1470 1480
pF1KA1 EVEQGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVEQGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNK
1460 1470 1480 1490 1500 1510
1490 1500 1510 1520 1530 1540
pF1KA1 SHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQH
1520 1530 1540 1550 1560 1570
1550 1560 1570 1580 1590 1600
pF1KA1 ADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMAL
1580 1590 1600 1610 1620 1630
1610 1620 1630 1640 1650 1660
pF1KA1 KNDETESRSIAQAGVQWQDLGSLQPLPPGFKRFSCLSFLSSWDYRRPPPRLANFCIFSRD
::::
XP_011 KNDE--------------------------------------------------------
1670 1680 1690 1700 1710 1720
pF1KA1 GVSPRWPGWSRSPDLTKALRLQIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFF
::::::::::::::::::::::::::::::::::::::
XP_011 ----------------------IIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFF
1640 1650 1660 1670
1730 1740 1750 1760 1770 1780
pF1KA1 TTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRK
1680 1690 1700 1710 1720 1730
1790 1800 1810 1820 1830 1840
pF1KA1 KDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFL
::: ::::::::::::
XP_011 KDS---------------------------------------------NTHSQSCLKSFL
1740 1750
1850 1860 1870 1880 1890 1900
pF1KA1 ERHGLSLLWIWMAELGDGRESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERHGLSLLWIWMAELGDGRESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTK
1760 1770 1780 1790 1800 1810
1910 1920 1930 1940 1950 1960
pF1KA1 TAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFRRLKIISENSMDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFRRLKIISENSMDS
1820 1830 1840 1850 1860 1870
1970 1980 1990 2000 2010 2020
pF1KA1 AISDATSELEGKDGKEDLDQLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AISDATSELEGKDGKEDLDQLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPT
1880 1890 1900 1910 1920 1930
2030 2040 2050 2060 2070 2080
pF1KA1 SEPEADAEIEPKESNGTKLEEPINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEPEADAEIEPKESNGTKLEEPINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATK
1940 1950 1960 1970 1980 1990
2090 2100 2110 2120 2130 2140
pF1KA1 LLDSWKDLKEVYRIPKKSQTEKENTTTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLDSWKDLKEVYRIPKKSQTEKENTTTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQN
2000 2010 2020 2030 2040 2050
2150 2160 2170 2180 2190 2200
pF1KA1 KEKRKRRSSLSPPSSAYERGTKRPDDRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEKRKRRSSLSPPSSAYERGTKRPDDRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQ
2060 2070 2080 2090 2100 2110
2210 2220 2230 2240 2250 2260
pF1KA1 REAQKQQQQMQNLGMTSPLPYDSLGYNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REAQKQQQQMQNLGMTSPLPYDSLGYNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPT
2120 2130 2140 2150 2160 2170
2270 2280 2290 2300 2310 2320
pF1KA1 PSMDPVCSPAPYDHAQPLVGHSTEPLSAPPPVPVVPHVAAPVEVSSSQYVAQSDGVVHQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSMDPVCSPAPYDHAQPLVGHSTEPLSAPPPVPVVPHVAAPVEVSSSQYVAQSDGVVHQD
2180 2190 2200 2210 2220 2230
2330 2340 2350 2360 2370 2380
pF1KA1 SSVAVLPVPAPGPVQGQNYSVWDSNQQSVSVQQQYSPAQSQATIYYQGQTCPTVYGVTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSVAVLPVPAPGPVQGQNYSVWDSNQQSVSVQQQYSPAQSQATIYYQGQTCPTVYGVTSP
2240 2250 2260 2270 2280 2290
2390 2400 2410 2420 2430 2440
pF1KA1 YSQTTPPIVQSYAQPSLQYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSQTTPPIVQSYAQPSLQYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVV
2300 2310 2320 2330 2340 2350
2450 2460 2470 2480 2490 2500
pF1KA1 TNNLLDLPPPSPPKPKTIVLPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNNLLDLPPPSPPKPKTIVLPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASL
2360 2370 2380 2390 2400 2410
2510 2520 2530 2540 2550 2560
pF1KA1 EHEAEMDLGTPTYDENPMKASKKPKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHEAEMDLGTPTYDENPMKASKKPKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRK
2420 2430 2440 2450 2460 2470
2570 2580 2590 2600 2610 2620
pF1KA1 PDCKVGRITTTEDFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDCKVGRITTTEDFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKF
2480 2490 2500 2510 2520 2530
2630 2640
pF1KA1 GAVYKPKEDTELE
:::::::::::::
XP_011 GAVYKPKEDTELE
2540
>>XP_011531933 (OMIM: 612778,616831) PREDICTED: histone- (2590 aa)
initn: 10606 init1: 10606 opt: 10606 Z-score: 4598.6 bits: 865.2 E(85289): 0
Smith-Waterman score: 16842; 96.9% identity (97.0% similar) in 2623 aa overlap (20-2642:46-2590)
10 20 30 40
pF1KA1 MKQLQPQPPPKMGDFYDPEHPTPEEEENEAKIENVQKTGFIKGPMFKGV
.: .:::::::::::::::::::::::::
XP_011 LLLASFCLTPYIQEAELFEGRDAALFKFGLQPLAQEEENEAKIENVQKTGFIKGPMFKGV
20 30 40 50 60 70
50 60 70 80 90 100
pF1KA1 ASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQ
80 90 100 110 120 130
110 120 130 140 150 160
pF1KA1 VDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTH
140 150 160 170 180 190
170 180 190 200 210 220
pF1KA1 AAPLPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAPLPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPL
200 210 220 230 240 250
230 240 250 260 270 280
pF1KA1 PVDVAVRSLKEPPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVDVAVRSLKEPPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKD
260 270 280 290 300 310
290 300 310 320 330 340
pF1KA1 EEIPDSSKISLSCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEIPDSSKISLSCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKER
320 330 340 350 360 370
350 360 370 380 390 400
pF1KA1 DFKKSSAPLKSEDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFKKSSAPLKSEDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRS
380 390 400 410 420 430
410 420 430 440 450 460
pF1KA1 ERGSRTNLSYSRSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERGSRTNLSYSRSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTY
440 450 460 470 480 490
470 480 490 500 510 520
pF1KA1 SRRTSSHSSSYRDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRRTSSHSSSYRDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKR
500 510 520 530 540 550
530 540 550 560 570 580
pF1KA1 CCSPPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CCSPPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFS
560 570 580 590 600 610
590 600 610 620 630 640
pF1KA1 LQTPCSKGSELRMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQTPCSKGSELRMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSI
620 630 640 650 660 670
650 660 670 680 690 700
pF1KA1 KELDSLSKVKNDQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KELDSLSKVKNDQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSP
680 690 700 710 720 730
710 720 730 740 750 760
pF1KA1 LVKACMLSSNGFQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVKACMLSSNGFQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVD
740 750 760 770 780 790
770 780 790 800 810 820
pF1KA1 YSKTVVKEPVDTRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSKTVVKEPVDTRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHL
800 810 820 830 840 850
830 840 850 860 870 880
pF1KA1 ESKPVICDSRNLTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESKPVICDSRNLTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPG
860 870 880 890 900 910
890 900 910 920 930 940
pF1KA1 IKVDSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKVDSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENR
920 930 940 950 960 970
950 960 970 980 990 1000
pF1KA1 RNNGLSGKCLQEAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNNGLSGKCLQEAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTM
980 990 1000 1010 1020 1030
1010 1020 1030 1040 1050 1060
pF1KA1 EDSDGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDSDGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSV
1040 1050 1060 1070 1080 1090
1070 1080 1090 1100 1110 1120
pF1KA1 VVVPKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVVPKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTD
1100 1110 1120 1130 1140 1150
1130 1140 1150 1160 1170 1180
pF1KA1 KFFLHKGTEKNPEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFFLHKGTEKNPEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEET
1160 1170 1180 1190 1200 1210
1190 1200 1210 1220 1230 1240
pF1KA1 VKAKIPSRQQEELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKAKIPSRQQEELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGL
1220 1230 1240 1250 1260 1270
1250 1260 1270 1280 1290 1300
pF1KA1 HSSEELRNLGWDFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSSEELRNLGWDFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPR
1280 1290 1300 1310 1320 1330
1310 1320 1330 1340 1350 1360
pF1KA1 SGRPPGTGVVYDRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGRPPGTGVVYDRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQA
1340 1350 1360 1370 1380 1390
1370 1380 1390 1400 1410 1420
pF1KA1 PEISSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEISSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRV
1400 1410 1420 1430 1440 1450
1430 1440 1450 1460 1470 1480
pF1KA1 EVEQGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVEQGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNK
1460 1470 1480 1490 1500 1510
1490 1500 1510 1520 1530 1540
pF1KA1 SHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQH
1520 1530 1540 1550 1560 1570
1550 1560 1570 1580 1590 1600
pF1KA1 ADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMAL
1580 1590 1600 1610 1620 1630
1610 1620 1630 1640 1650 1660
pF1KA1 KNDETESRSIAQAGVQWQDLGSLQPLPPGFKRFSCLSFLSSWDYRRPPPRLANFCIFSRD
::::
XP_011 KNDE--------------------------------------------------------
1670 1680 1690 1700 1710 1720
pF1KA1 GVSPRWPGWSRSPDLTKALRLQIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFF
::::::::::::::::::::::::::::::::::::::
XP_011 ----------------------IIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFF
1640 1650 1660 1670
1730 1740 1750 1760 1770 1780
pF1KA1 TTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRK
1680 1690 1700 1710 1720 1730
1790 1800 1810 1820 1830 1840
pF1KA1 KDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFL
1740 1750 1760 1770 1780 1790
1850 1860 1870 1880 1890 1900
pF1KA1 ERHGLSLLWIWMAELGDGRESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERHGLSLLWIWMAELGDGRESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTK
1800 1810 1820 1830 1840 1850
1910 1920 1930 1940 1950 1960
pF1KA1 TAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFRRLKIISENSMDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFRRLKIISENSMDS
1860 1870 1880 1890 1900 1910
1970 1980 1990 2000 2010 2020
pF1KA1 AISDATSELEGKDGKEDLDQLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AISDATSELEGKDGKEDLDQLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPT
1920 1930 1940 1950 1960 1970
2030 2040 2050 2060 2070 2080
pF1KA1 SEPEADAEIEPKESNGTKLEEPINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEPEADAEIEPKESNGTKLEEPINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATK
1980 1990 2000 2010 2020 2030
2090 2100 2110 2120 2130 2140
pF1KA1 LLDSWKDLKEVYRIPKKSQTEKENTTTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLDSWKDLKEVYRIPKKSQTEKENTTTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQN
2040 2050 2060 2070 2080 2090
2150 2160 2170 2180 2190 2200
pF1KA1 KEKRKRRSSLSPPSSAYERGTKRPDDRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEKRKRRSSLSPPSSAYERGTKRPDDRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQ
2100 2110 2120 2130 2140 2150
2210 2220 2230 2240 2250 2260
pF1KA1 REAQKQQQQMQNLGMTSPLPYDSLGYNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REAQKQQQQMQNLGMTSPLPYDSLGYNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPT
2160 2170 2180 2190 2200 2210
2270 2280 2290 2300 2310 2320
pF1KA1 PSMDPVCSPAPYDHAQPLVGHSTEPLSAPPPVPVVPHVAAPVEVSSSQYVAQSDGVVHQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSMDPVCSPAPYDHAQPLVGHSTEPLSAPPPVPVVPHVAAPVEVSSSQYVAQSDGVVHQD
2220 2230 2240 2250 2260 2270
2330 2340 2350 2360 2370 2380
pF1KA1 SSVAVLPVPAPGPVQGQNYSVWDSNQQSVSVQQQYSPAQSQATIYYQGQTCPTVYGVTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSVAVLPVPAPGPVQGQNYSVWDSNQQSVSVQQQYSPAQSQATIYYQGQTCPTVYGVTSP
2280 2290 2300 2310 2320 2330
2390 2400 2410 2420 2430 2440
pF1KA1 YSQTTPPIVQSYAQPSLQYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSQTTPPIVQSYAQPSLQYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVV
2340 2350 2360 2370 2380 2390
2450 2460 2470 2480 2490 2500
pF1KA1 TNNLLDLPPPSPPKPKTIVLPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNNLLDLPPPSPPKPKTIVLPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASL
2400 2410 2420 2430 2440 2450
2510 2520 2530 2540 2550 2560
pF1KA1 EHEAEMDLGTPTYDENPMKASKKPKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHEAEMDLGTPTYDENPMKASKKPKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRK
2460 2470 2480 2490 2500 2510
2570 2580 2590 2600 2610 2620
pF1KA1 PDCKVGRITTTEDFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDCKVGRITTTEDFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKF
2520 2530 2540 2550 2560 2570
2630 2640
pF1KA1 GAVYKPKEDTELE
:::::::::::::
XP_011 GAVYKPKEDTELE
2580 2590
>>XP_011531936 (OMIM: 612778,616831) PREDICTED: histone- (2520 aa)
initn: 10467 init1: 10467 opt: 10467 Z-score: 4538.7 bits: 854.0 E(85289): 0
Smith-Waterman score: 16703; 97.0% identity (97.0% similar) in 2598 aa overlap (45-2642:1-2520)
20 30 40 50 60 70
pF1KA1 FYDPEHPTPEEEENEAKIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVS
::::::::::::::::::::::::::::::
XP_011 MFKGVASSRFLPKGTKTKVNLEEQGRQKVS
10 20 30
80 90 100 110 120 130
pF1KA1 FSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPK
40 50 60 70 80 90
140 150 160 170 180 190
pF1KA1 SRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTHAAPLPAVIAESTTVDSPPSSPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTHAAPLPAVIAESTTVDSPPSSPPPPP
100 110 120 130 140 150
200 210 220 230 240 250
pF1KA1 PPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPLPVDVAVRSLKEPPIIIVPESLEADT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPLPVDVAVRSLKEPPIIIVPESLEADT
160 170 180 190 200 210
260 270 280 290 300 310
pF1KA1 KQDTISNSLEEHVTQILNEQADISSKKEDSHIGKDEEIPDSSKISLSCKKTGSKKKSSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQDTISNSLEEHVTQILNEQADISSKKEDSHIGKDEEIPDSSKISLSCKKTGSKKKSSQS
220 230 240 250 260 270
320 330 340 350 360 370
pF1KA1 EGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKSEDLGKPSRSKTDRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKSEDLGKPSRSKTDRD
280 290 300 310 320 330
380 390 400 410 420 430
pF1KA1 DKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRSERGSRTNLSYSRSERSHYYDSDRRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRSERGSRTNLSYSRSERSHYYDSDRRY
340 350 360 370 380 390
440 450 460 470 480 490
pF1KA1 HRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRTSSHSSSYRDLRTSSYSKSDRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRTSSHSSSYRDLRTSSYSKSDRD
400 410 420 430 440 450
500 510 520 530 540 550
pF1KA1 CKTETSYLEMERRGKYSSKLERESKRTSENEAIKRCCSPPNELGFRRGSSYSKHDSSASR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CKTETSYLEMERRGKYSSKLERESKRTSENEAIKRCCSPPNELGFRRGSSYSKHDSSASR
460 470 480 490 500 510
560 570 580 590 600 610
pF1KA1 YKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFSLQTPCSKGSELRMINKNPEREKAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFSLQTPCSKGSELRMINKNPEREKAGS
520 530 540 550 560 570
620 630 640 650 660 670
pF1KA1 PAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSIKELDSLSKVKNDQLRSFCPIELNIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSIKELDSLSKVKNDQLRSFCPIELNIN
580 590 600 610 620 630
680 690 700 710 720 730
pF1KA1 GSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSPLVKACMLSSNGFQNISRCKEKDLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSPLVKACMLSSNGFQNISRCKEKDLDD
640 650 660 670 680 690
740 750 760 770 780 790
pF1KA1 TCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVDYSKTVVKEPVDTRVSCCKTKDSDIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVDYSKTVVKEPVDTRVSCCKTKDSDIY
700 710 720 730 740 750
800 810 820 830 840 850
pF1KA1 CTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHLESKPVICDSRNLTDHSKFACEEYKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHLESKPVICDSRNLTDHSKFACEEYKQ
760 770 780 790 800 810
860 870 880 890 900 910
pF1KA1 SIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPGIKVDSLTLLKCGENTSPVLDAVLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPGIKVDSLTLLKCGENTSPVLDAVLKS
820 830 840 850 860 870
920 930 940 950 960 970
pF1KA1 KKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENRRNNGLSGKCLQEAQEEGNSILPERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENRRNNGLSGKCLQEAQEEGNSILPERR
880 890 900 910 920 930
980 990 1000 1010 1020 1030
pF1KA1 GRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDGVTYALKCDSSGHAPEIVSTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDGVTYALKCDSSGHAPEIVSTV
940 950 960 970 980 990
1040 1050 1060 1070 1080 1090
pF1KA1 HEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSVVVVPKNSTLPMEETSPCSSRSSQSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSVVVVPKNSTLPMEETSPCSSRSSQSY
1000 1010 1020 1030 1040 1050
1100 1110 1120 1130 1140 1150
pF1KA1 RHYSDHWEDERLESRRHLYEEKFESIASKACPQTDKFFLHKGTEKNPEISFTQSSRKQID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHYSDHWEDERLESRRHLYEEKFESIASKACPQTDKFFLHKGTEKNPEISFTQSSRKQID
1060 1070 1080 1090 1100 1110
1160 1170 1180 1190 1200 1210
pF1KA1 NRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEETVKAKIPSRQQEELPIYSSDFEDVPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEETVKAKIPSRQQEELPIYSSDFEDVPN
1120 1130 1140 1150 1160 1170
1220 1230 1240 1250 1260 1270
pF1KA1 KSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGLHSSEELRNLGWDFSQEKPSTTYQQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGLHSSEELRNLGWDFSQEKPSTTYQQP
1180 1190 1200 1210 1220 1230
1280 1290 1300 1310 1320 1330
pF1KA1 DSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPRSGRPPGTGVVYDRTQGQVPDSLTDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPRSGRPPGTGVVYDRTQGQVPDSLTDD
1240 1250 1260 1270 1280 1290
1340 1350 1360 1370 1380 1390
pF1KA1 REEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQAPEISSNSIKDTLAVNEKKDFSKNLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQAPEISSNSIKDTLAVNEKKDFSKNLE
1300 1310 1320 1330 1340 1350
1400 1410 1420 1430 1440 1450
pF1KA1 KNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRVEVEQGETSVPPGSALVGPSCVMDDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRVEVEQGETSVPPGSALVGPSCVMDDF
1360 1370 1380 1390 1400 1410
1460 1470 1480 1490 1500 1510
pF1KA1 RDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEI
1420 1430 1440 1450 1460 1470
1520 1530 1540 1550 1560 1570
pF1KA1 ACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNT
1480 1490 1500 1510 1520 1530
1580 1590 1600 1610 1620 1630
pF1KA1 FVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDETESRSIAQAGVQWQDLGSLQP
:::::::::::::::::::::::::::::::::::::::
XP_011 FVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDE---------------------
1540 1550 1560
1640 1650 1660 1670 1680 1690
pF1KA1 LPPGFKRFSCLSFLSSWDYRRPPPRLANFCIFSRDGVSPRWPGWSRSPDLTKALRLQIID
:::
XP_011 ---------------------------------------------------------IID
1570
1700 1710 1720 1730 1740 1750
pF1KA1 ATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQ
1580 1590 1600 1610 1620 1630
1760 1770 1780 1790 1800 1810
pF1KA1 KCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVL
1640 1650 1660 1670 1680 1690
1820 1830 1840 1850 1860 1870
pF1KA1 SLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRESNQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRESNQKL
1700 1710 1720 1730 1740 1750
1880 1890 1900 1910 1920 1930
pF1KA1 QEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLN
1760 1770 1780 1790 1800 1810
1940 1950 1960 1970 1980 1990
pF1KA1 TPDPSTKLSTEADTDTPKKLMFRRLKIISENSMDSAISDATSELEGKDGKEDLDQLENVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPDPSTKLSTEADTDTPKKLMFRRLKIISENSMDSAISDATSELEGKDGKEDLDQLENVP
1820 1830 1840 1850 1860 1870
2000 2010 2020 2030 2040 2050
pF1KA1 VEEEEELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEPKESNGTKLEEPINE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEEEEELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEPKESNGTKLEEPINE
1880 1890 1900 1910 1920 1930
2060 2070 2080 2090 2100 2110
pF1KA1 ETPSQDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETPSQDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENT
1940 1950 1960 1970 1980 1990
2120 2130 2140 2150 2160 2170
pF1KA1 TTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQNKEKRKRRSSLSPPSSAYERGTKRPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQNKEKRKRRSSLSPPSSAYERGTKRPD
2000 2010 2020 2030 2040 2050
2180 2190 2200 2210 2220 2230
pF1KA1 DRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSPLPYDSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSPLPYDSLG
2060 2070 2080 2090 2100 2110
2240 2250 2260 2270 2280 2290
pF1KA1 YNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPLVGHSTEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPLVGHSTEP
2120 2130 2140 2150 2160 2170
2300 2310 2320 2330 2340 2350
pF1KA1 LSAPPPVPVVPHVAAPVEVSSSQYVAQSDGVVHQDSSVAVLPVPAPGPVQGQNYSVWDSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSAPPPVPVVPHVAAPVEVSSSQYVAQSDGVVHQDSSVAVLPVPAPGPVQGQNYSVWDSN
2180 2190 2200 2210 2220 2230
2360 2370 2380 2390 2400 2410
pF1KA1 QQSVSVQQQYSPAQSQATIYYQGQTCPTVYGVTSPYSQTTPPIVQSYAQPSLQYIQGQQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQSVSVQQQYSPAQSQATIYYQGQTCPTVYGVTSPYSQTTPPIVQSYAQPSLQYIQGQQI
2240 2250 2260 2270 2280 2290
2420 2430 2440 2450 2460 2470
pF1KA1 FTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNNLLDLPPPSPPKPKTIVLPPNWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNNLLDLPPPSPPKPKTIVLPPNWK
2300 2310 2320 2330 2340 2350
2480 2490 2500 2510 2520 2530
pF1KA1 TARDPEGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPMKASKKPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TARDPEGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPMKASKKPK
2360 2370 2380 2390 2400 2410
2540 2550 2560 2570 2580 2590
pF1KA1 TAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLARKLTHGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLARKLTHGV
2420 2430 2440 2450 2460 2470
2600 2610 2620 2630 2640
pF1KA1 MNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTELE
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTELE
2480 2490 2500 2510 2520
>>XP_016861759 (OMIM: 612778,616831) PREDICTED: histone- (2490 aa)
initn: 10341 init1: 10341 opt: 10341 Z-score: 4484.3 bits: 844.0 E(85289): 0
Smith-Waterman score: 15947; 93.1% identity (93.1% similar) in 2623 aa overlap (20-2642:46-2490)
10 20 30 40
pF1KA1 MKQLQPQPPPKMGDFYDPEHPTPEEEENEAKIENVQKTGFIKGPMFKGV
.: .:::::::::::::::::::::::::
XP_016 LLLASFCLTPYIQEAELFEGRDAALFKFGLQPLAQEEENEAKIENVQKTGFIKGPMFKGV
20 30 40 50 60 70
50 60 70 80 90 100
pF1KA1 ASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQ
80 90 100 110 120 130
110 120 130 140 150 160
pF1KA1 VDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTH
140 150 160 170 180 190
170 180 190 200 210 220
pF1KA1 AAPLPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAPLPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPL
200 210 220 230 240 250
230 240 250 260 270 280
pF1KA1 PVDVAVRSLKEPPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVDVAVRSLKEPPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKD
260 270 280 290 300 310
290 300 310 320 330 340
pF1KA1 EEIPDSSKISLSCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEIPDSSKISLSCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKER
320 330 340 350 360 370
350 360 370 380 390 400
pF1KA1 DFKKSSAPLKSEDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFKKSSAPLKSEDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRS
380 390 400 410 420 430
410 420 430 440 450 460
pF1KA1 ERGSRTNLSYSRSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERGSRTNLSYSRSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTY
440 450 460 470 480 490
470 480 490 500 510 520
pF1KA1 SRRTSSHSSSYRDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRRTSSHSSSYRDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKR
500 510 520 530 540 550
530 540 550 560 570 580
pF1KA1 CCSPPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CCSPPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFS
560 570 580 590 600 610
590 600 610 620 630 640
pF1KA1 LQTPCSKGSELRMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQTPCSKGSELRMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSI
620 630 640 650 660 670
650 660 670 680 690 700
pF1KA1 KELDSLSKVKNDQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KELDSLSKVKNDQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSP
680 690 700 710 720 730
710 720 730 740 750 760
pF1KA1 LVKACMLSSNGFQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVKACMLSSNGFQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVD
740 750 760 770 780 790
770 780 790 800 810 820
pF1KA1 YSKTVVKEPVDTRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YSKTVVKEPVDTRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHL
800 810 820 830 840 850
830 840 850 860 870 880
pF1KA1 ESKPVICDSRNLTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESKPVICDSRNLTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPG
860 870 880 890 900 910
890 900 910 920 930 940
pF1KA1 IKVDSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKVDSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENR
920 930 940 950 960 970
950 960 970 980 990 1000
pF1KA1 RNNGLSGKCLQEAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNNGLSGKCLQEAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTM
980 990 1000 1010 1020 1030
1010 1020 1030 1040 1050 1060
pF1KA1 EDSDGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDSDGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSV
1040 1050 1060 1070 1080 1090
1070 1080 1090 1100 1110 1120
pF1KA1 VVVPKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVVPKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTD
1100 1110 1120 1130 1140 1150
1130 1140 1150 1160 1170 1180
pF1KA1 KFFLHKGTEKNPEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFFLHKGTEKNPEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEET
1160 1170 1180 1190 1200 1210
1190 1200 1210 1220 1230 1240
pF1KA1 VKAKIPSRQQEELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKAKIPSRQQEELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGL
1220 1230 1240 1250 1260 1270
1250 1260 1270 1280 1290 1300
pF1KA1 HSSEELRNLGWDFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSSEELRNLGWDFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPR
1280 1290 1300 1310 1320 1330
1310 1320 1330 1340 1350 1360
pF1KA1 SGRPPGTGVVYDRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGRPPGTGVVYDRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQA
1340 1350 1360 1370 1380 1390
1370 1380 1390 1400 1410 1420
pF1KA1 PEISSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEISSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRV
1400 1410 1420 1430 1440 1450
1430 1440 1450 1460 1470 1480
pF1KA1 EVEQGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVEQGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNK
1460 1470 1480 1490 1500 1510
1490 1500 1510 1520 1530 1540
pF1KA1 SHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQH
1520 1530 1540 1550 1560 1570
1550 1560 1570 1580 1590 1600
pF1KA1 ADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMAL
:::::::::::::::::::::::
XP_016 ADVEVILTEKKGWGLRAAKDLPS-------------------------------------
1580 1590
1610 1620 1630 1640 1650 1660
pF1KA1 KNDETESRSIAQAGVQWQDLGSLQPLPPGFKRFSCLSFLSSWDYRRPPPRLANFCIFSRD
XP_016 ------------------------------------------------------------
1670 1680 1690 1700 1710 1720
pF1KA1 GVSPRWPGWSRSPDLTKALRLQIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFF
XP_016 ------------------------------------------------------------
1730 1740 1750 1760 1770 1780
pF1KA1 TTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRK
:::::::::::::::::::::::::::::::::::::::
XP_016 ---------------------KEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRK
1600 1610 1620 1630
1790 1800 1810 1820 1830 1840
pF1KA1 KDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFL
1640 1650 1660 1670 1680 1690
1850 1860 1870 1880 1890 1900
pF1KA1 ERHGLSLLWIWMAELGDGRESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERHGLSLLWIWMAELGDGRESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTK
1700 1710 1720 1730 1740 1750
1910 1920 1930 1940 1950 1960
pF1KA1 TAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFRRLKIISENSMDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFRRLKIISENSMDS
1760 1770 1780 1790 1800 1810
1970 1980 1990 2000 2010 2020
pF1KA1 AISDATSELEGKDGKEDLDQLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AISDATSELEGKDGKEDLDQLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPT
1820 1830 1840 1850 1860 1870
2030 2040 2050 2060 2070 2080
pF1KA1 SEPEADAEIEPKESNGTKLEEPINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEPEADAEIEPKESNGTKLEEPINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATK
1880 1890 1900 1910 1920 1930
2090 2100 2110 2120 2130 2140
pF1KA1 LLDSWKDLKEVYRIPKKSQTEKENTTTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLDSWKDLKEVYRIPKKSQTEKENTTTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQN
1940 1950 1960 1970 1980 1990
2150 2160 2170 2180 2190 2200
pF1KA1 KEKRKRRSSLSPPSSAYERGTKRPDDRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEKRKRRSSLSPPSSAYERGTKRPDDRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQ
2000 2010 2020 2030 2040 2050
2210 2220 2230 2240 2250 2260
pF1KA1 REAQKQQQQMQNLGMTSPLPYDSLGYNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REAQKQQQQMQNLGMTSPLPYDSLGYNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPT
2060 2070 2080 2090 2100 2110
2270 2280 2290 2300 2310 2320
pF1KA1 PSMDPVCSPAPYDHAQPLVGHSTEPLSAPPPVPVVPHVAAPVEVSSSQYVAQSDGVVHQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSMDPVCSPAPYDHAQPLVGHSTEPLSAPPPVPVVPHVAAPVEVSSSQYVAQSDGVVHQD
2120 2130 2140 2150 2160 2170
2330 2340 2350 2360 2370 2380
pF1KA1 SSVAVLPVPAPGPVQGQNYSVWDSNQQSVSVQQQYSPAQSQATIYYQGQTCPTVYGVTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSVAVLPVPAPGPVQGQNYSVWDSNQQSVSVQQQYSPAQSQATIYYQGQTCPTVYGVTSP
2180 2190 2200 2210 2220 2230
2390 2400 2410 2420 2430 2440
pF1KA1 YSQTTPPIVQSYAQPSLQYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YSQTTPPIVQSYAQPSLQYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVV
2240 2250 2260 2270 2280 2290
2450 2460 2470 2480 2490 2500
pF1KA1 TNNLLDLPPPSPPKPKTIVLPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNNLLDLPPPSPPKPKTIVLPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASL
2300 2310 2320 2330 2340 2350
2510 2520 2530 2540 2550 2560
pF1KA1 EHEAEMDLGTPTYDENPMKASKKPKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHEAEMDLGTPTYDENPMKASKKPKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRK
2360 2370 2380 2390 2400 2410
2570 2580 2590 2600 2610 2620
pF1KA1 PDCKVGRITTTEDFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDCKVGRITTTEDFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKF
2420 2430 2440 2450 2460 2470
2630 2640
pF1KA1 GAVYKPKEDTELE
:::::::::::::
XP_016 GAVYKPKEDTELE
2480 2490
>>NP_001308207 (OMIM: 608753,612389) tRNA-splicing endon (516 aa)
initn: 436 init1: 398 opt: 402 Z-score: 198.3 bits: 48.7 E(85289): 0.00026
Smith-Waterman score: 402; 73.7% identity (86.8% similar) in 76 aa overlap (1609-1684:440-515)
1580 1590 1600 1610 1620 1630
pF1KA1 YCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDETESRSIAQAGVQWQDLGSLQPLPPG
.: ...:::..::::: ::::::::: :
NP_001 VSVNVSKELMLCYLIKPSTMTDKEMESPECMKRIKVQSRSVVQAGVQCCDLGSLQPLPAG
410 420 430 440 450 460
1640 1650 1660 1670 1680 1690
pF1KA1 FKRFSCLSFLSSWDYRRPPPRLANFCIFSRDGVSPRWPGWSRSPDLTKALRLQIIDATQK
::::::::.:::::::. ::. :::::::::::: ::::: .:::
NP_001 FKRFSCLSLLSSWDYRHAPPHTANFCIFSRDGVSLCWPGWSGTPDLK
470 480 490 500 510
1700 1710 1720 1730 1740 1750
pF1KA1 GNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFC
>>NP_001287848 (OMIM: 150699,600698) high mobility group (147 aa)
initn: 383 init1: 383 opt: 383 Z-score: 198.0 bits: 46.8 E(85289): 0.00027
Smith-Waterman score: 383; 79.4% identity (88.9% similar) in 63 aa overlap (1622-1684:84-146)
1600 1610 1620 1630 1640 1650
pF1KA1 RVKEYARNKNIHYYFMALKNDETESRSIAQAGVQWQDLGSLQPLPPGFKRFSCLSFLSSW
::::: .:::::: :: ::.:::: .::::
NP_001 GSKNKSPSKAAQKKAEATGEKRPRGRPRKWAGVQWYNLGSLQPPPPRFKQFSCLRLLSSW
60 70 80 90 100 110
1660 1670 1680 1690 1700 1710
pF1KA1 DYRRPPPRLANFCIFSRDGVSPRWPGWSRSPDLTKALRLQIIDATQKGNCSRFMNHSCEP
:::.:::. ::::::::: ::: ::::::.:::
NP_001 DYRHPPPHPANFCIFSRDRVSPCWPGWSRTPDLR
120 130 140
1720 1730 1740 1750 1760 1770
pF1KA1 NCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGEN
>>NP_001304977 (OMIM: 616380) laminin subunit beta-4 iso (772 aa)
initn: 427 init1: 387 opt: 394 Z-score: 192.3 bits: 48.1 E(85289): 0.00057
Smith-Waterman score: 394; 62.1% identity (82.8% similar) in 87 aa overlap (1601-1684:685-771)
1580 1590 1600 1610 1620
pF1KA1 PSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDETESRS---IAQAGVQWQ
.: :: . :....: . .:.:::.
NP_001 QSKPQSFALPAATRIMLLPTPICLEPDVQYSIDVYFSQPLQGESHAHSHVLVDSAAVQWH
660 670 680 690 700 710
1630 1640 1650 1660 1670 1680
pF1KA1 DLGSLQPLPPGFKRFSCLSFLSSWDYRRPPPRLANFCIFSRDGVSPRWPGWSRSPDLTKA
.:::::: :: :.:::.:: ::::::.:::.::::::::::::::.:::::..:::
NP_001 NLGSLQPPPPECKQFSCFSFPSSWDYRHPPPHLANFCIFSRDGVSPHWPGWSQTPDLR
720 730 740 750 760 770
1690 1700 1710 1720 1730 1740
pF1KA1 LRLQIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQ
>>XP_016864077 (OMIM: 194190,602952) PREDICTED: histone- (584 aa)
initn: 661 init1: 361 opt: 381 Z-score: 188.5 bits: 47.0 E(85289): 0.00093
Smith-Waterman score: 541; 31.6% identity (53.6% similar) in 351 aa overlap (1493-1835:228-489)
1470 1480 1490 1500 1510
pF1KA1 CAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRM-QCECTPLSKDERAQGEIACGED--
::... .:.: : . : :: :
XP_016 RETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTD-------ENPCGFDSE
200 210 220 230 240 250
1520 1530 1540 1550 1560 1570
pF1KA1 CLNRLLMIECSSR-CPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLE
::::.::.:: . :: :..:.:. : ..:. ....: :. ::::: : .:. .. :: :
XP_016 CLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNE
260 270 280 290 300 310
1580 1590 1600 1610 1620 1630
pF1KA1 YCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDETESRSIAQAGVQWQDLGSLQPLPPG
: ::..:..: ::.:. .: :.:.... .:
XP_016 YVGELIDEEECMARIKHAHENDITHFYMLTIDKD--------------------------
320 330 340
1640 1650 1660 1670 1680 1690
pF1KA1 FKRFSCLSFLSSWDYRRPPPRLANFCIFSRDGVSPRWPGWSRSPDLTKALRLQIIDATQK
.:::: :
XP_016 ----------------------------------------------------RIIDAGPK
350
1700 1710 1720 1730 1740 1750
pF1KA1 GNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFC
:: ::::::::.::::: ::::::. :::.:.. .:.:.::::.:... :.: : :
XP_016 GNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRC
360 370 380 390 400 410
1760 1770 1780 1790 1800 1810
pF1KA1 GSANCRGYLGGENRVSIRAA----GGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVL
:..:: :.:: . ..: . : : ::. :.. . .:. .. : . .: .:..
XP_016 GASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFR-CGDGGQLV
420 430 440 450 460 470
1820 1830 1840 1850 1860 1870
pF1KA1 SLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRESNQKL
.: .. : .:.:: :
XP_016 LCDR---KFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQD
480 490 500 510 520
2642 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 21:55:47 2016 done: Wed Nov 2 21:55:51 2016
Total Scan time: 27.560 Total Display time: 1.500
Function used was FASTA [36.3.4 Apr, 2011]