FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1739, 833 aa
1>>>pF1KA1739 833 - 833 aa - 833 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.0875+/-0.000374; mu= 3.5984+/- 0.023
mean_var=185.9941+/-37.228, 0's: 0 Z-trim(120.2): 195 B-trim: 687 in 1/54
Lambda= 0.094043
statistics sampled from 34965 (35162) to 34965 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.736), E-opt: 0.2 (0.412), width: 16
Scan time: 13.360
The best scores are: opt bits E(85289)
XP_011509685 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 5771 795.7 0
XP_011509682 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 5771 795.7 0
XP_011509683 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 5771 795.7 0
NP_060259 (OMIM: 604462) semaphorin-4C precursor [ ( 833) 5771 795.7 0
XP_011509680 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 5771 795.7 0
XP_011509681 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 5771 795.7 0
XP_011509684 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 5771 795.7 0
XP_016859882 (OMIM: 604462) PREDICTED: semaphorin- ( 875) 5771 795.7 0
XP_016859883 (OMIM: 604462) PREDICTED: semaphorin- ( 692) 4804 664.5 4.6e-190
XP_006712669 (OMIM: 604462) PREDICTED: semaphorin- ( 495) 3349 467.0 9.2e-131
XP_016869682 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63
XP_016869684 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63
XP_011516431 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63
XP_011516430 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63
XP_016869686 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63
XP_016869687 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63
XP_005251711 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63
XP_011516433 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63
NP_006369 (OMIM: 601866) semaphorin-4D isoform 1 p ( 862) 1700 243.4 3.3e-63
XP_016869683 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63
XP_011516432 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63
XP_011516436 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63
XP_011516425 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63
XP_011516426 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63
XP_011516429 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63
XP_011516435 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63
XP_011516427 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63
XP_016869685 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63
NP_001135759 (OMIM: 601866) semaphorin-4D isoform ( 738) 1636 234.7 1.2e-60
NP_001310961 (OMIM: 617029) semaphorin-4B isoform ( 602) 1622 232.7 3.7e-60
NP_064595 (OMIM: 617029) semaphorin-4B isoform 1 p ( 837) 1624 233.1 4.1e-60
NP_945119 (OMIM: 617029) semaphorin-4B isoform 1 p ( 837) 1624 233.1 4.1e-60
NP_001310960 (OMIM: 617029) semaphorin-4B isoform ( 890) 1624 233.1 4.3e-60
XP_016869688 (OMIM: 601866) PREDICTED: semaphorin- ( 534) 1418 205.0 7.2e-52
NP_001310963 (OMIM: 617029) semaphorin-4B isoform ( 847) 1410 204.0 2.3e-51
XP_011530777 (OMIM: 603706) PREDICTED: semaphorin- ( 624) 1395 201.9 7.2e-51
NP_004254 (OMIM: 603706) semaphorin-4F isoform 1 p ( 770) 1395 202.0 8.6e-51
XP_011530779 (OMIM: 603706) PREDICTED: semaphorin- ( 597) 1354 196.4 3.3e-49
XP_011530778 (OMIM: 603706) PREDICTED: semaphorin- ( 600) 1351 196.0 4.4e-49
NP_001310962 (OMIM: 617029) semaphorin-4B isoform ( 681) 1340 194.5 1.4e-48
NP_001310959 (OMIM: 617029) semaphorin-4B isoform ( 681) 1340 194.5 1.4e-48
XP_016858661 (OMIM: 603706) PREDICTED: semaphorin- ( 668) 1297 188.7 7.7e-47
XP_005265439 (OMIM: 601124) PREDICTED: semaphorin- ( 754) 1165 170.8 2.1e-41
NP_001305729 (OMIM: 601124) semaphorin-3F isoform ( 754) 1165 170.8 2.1e-41
NP_001305727 (OMIM: 601124) semaphorin-3F isoform ( 686) 1158 169.8 3.7e-41
XP_016858662 (OMIM: 603706) PREDICTED: semaphorin- ( 635) 1139 167.2 2.1e-40
NP_001258591 (OMIM: 603706) semaphorin-4F isoform ( 737) 1139 167.2 2.4e-40
NP_004627 (OMIM: 601281) semaphorin-3B isoform 1 p ( 749) 1132 166.3 4.6e-40
NP_001276989 (OMIM: 601281) semaphorin-3B isoform ( 749) 1132 166.3 4.6e-40
XP_005250168 (OMIM: 603961,614897) PREDICTED: sema ( 771) 1099 161.8 1.1e-38
>>XP_011509685 (OMIM: 604462) PREDICTED: semaphorin-4C i (833 aa)
initn: 5771 init1: 5771 opt: 5771 Z-score: 4241.0 bits: 795.7 E(85289): 0
Smith-Waterman score: 5771; 100.0% identity (100.0% similar) in 833 aa overlap (1-833:1-833)
10 20 30 40 50 60
pF1KA1 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG
730 740 750 760 770 780
790 800 810 820 830
pF1KA1 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV
790 800 810 820 830
>>XP_011509682 (OMIM: 604462) PREDICTED: semaphorin-4C i (833 aa)
initn: 5771 init1: 5771 opt: 5771 Z-score: 4241.0 bits: 795.7 E(85289): 0
Smith-Waterman score: 5771; 100.0% identity (100.0% similar) in 833 aa overlap (1-833:1-833)
10 20 30 40 50 60
pF1KA1 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG
730 740 750 760 770 780
790 800 810 820 830
pF1KA1 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV
790 800 810 820 830
>>XP_011509683 (OMIM: 604462) PREDICTED: semaphorin-4C i (833 aa)
initn: 5771 init1: 5771 opt: 5771 Z-score: 4241.0 bits: 795.7 E(85289): 0
Smith-Waterman score: 5771; 100.0% identity (100.0% similar) in 833 aa overlap (1-833:1-833)
10 20 30 40 50 60
pF1KA1 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG
730 740 750 760 770 780
790 800 810 820 830
pF1KA1 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV
790 800 810 820 830
>>NP_060259 (OMIM: 604462) semaphorin-4C precursor [Homo (833 aa)
initn: 5771 init1: 5771 opt: 5771 Z-score: 4241.0 bits: 795.7 E(85289): 0
Smith-Waterman score: 5771; 100.0% identity (100.0% similar) in 833 aa overlap (1-833:1-833)
10 20 30 40 50 60
pF1KA1 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG
730 740 750 760 770 780
790 800 810 820 830
pF1KA1 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV
790 800 810 820 830
>>XP_011509680 (OMIM: 604462) PREDICTED: semaphorin-4C i (833 aa)
initn: 5771 init1: 5771 opt: 5771 Z-score: 4241.0 bits: 795.7 E(85289): 0
Smith-Waterman score: 5771; 100.0% identity (100.0% similar) in 833 aa overlap (1-833:1-833)
10 20 30 40 50 60
pF1KA1 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG
730 740 750 760 770 780
790 800 810 820 830
pF1KA1 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV
790 800 810 820 830
>>XP_011509681 (OMIM: 604462) PREDICTED: semaphorin-4C i (833 aa)
initn: 5771 init1: 5771 opt: 5771 Z-score: 4241.0 bits: 795.7 E(85289): 0
Smith-Waterman score: 5771; 100.0% identity (100.0% similar) in 833 aa overlap (1-833:1-833)
10 20 30 40 50 60
pF1KA1 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG
730 740 750 760 770 780
790 800 810 820 830
pF1KA1 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV
790 800 810 820 830
>>XP_011509684 (OMIM: 604462) PREDICTED: semaphorin-4C i (833 aa)
initn: 5771 init1: 5771 opt: 5771 Z-score: 4241.0 bits: 795.7 E(85289): 0
Smith-Waterman score: 5771; 100.0% identity (100.0% similar) in 833 aa overlap (1-833:1-833)
10 20 30 40 50 60
pF1KA1 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG
730 740 750 760 770 780
790 800 810 820 830
pF1KA1 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV
790 800 810 820 830
>>XP_016859882 (OMIM: 604462) PREDICTED: semaphorin-4C i (875 aa)
initn: 5771 init1: 5771 opt: 5771 Z-score: 4240.7 bits: 795.7 E(85289): 0
Smith-Waterman score: 5771; 100.0% identity (100.0% similar) in 833 aa overlap (1-833:43-875)
10 20 30
pF1KA1 MAPHWAVWLLAARLWGLGIGAEVWWNLVPR
::::::::::::::::::::::::::::::
XP_016 SGLLSLAVISDHVFSLSRTAGLKLRAGACAMAPHWAVWLLAARLWGLGIGAEVWWNLVPR
20 30 40 50 60 70
40 50 60 70 80 90
pF1KA1 KTVSSGELATVVRRFSQTGIQDFLTLTLTEPTGLLYVGAREALFAFSMEALELQGAISWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTVSSGELATVVRRFSQTGIQDFLTLTLTEPTGLLYVGAREALFAFSMEALELQGAISWE
80 90 100 110 120 130
100 110 120 130 140 150
pF1KA1 APVEKKTECIQKGKNNQTECFNFIRFLQPYNASHLYVCGTYAFQPKCTYVNMLTFTLEHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APVEKKTECIQKGKNNQTECFNFIRFLQPYNASHLYVCGTYAFQPKCTYVNMLTFTLEHG
140 150 160 170 180 190
160 170 180 190 200 210
pF1KA1 EFEDGKGKCPYDPAKGHAGLLVDGELYSATLNNFLGTEPIILRNMGPHHSMKTEYLAFWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFEDGKGKCPYDPAKGHAGLLVDGELYSATLNNFLGTEPIILRNMGPHHSMKTEYLAFWL
200 210 220 230 240 250
220 230 240 250 260 270
pF1KA1 NEPHFVGSAYVPESVGSFTGDDDKVYFFFRERAVESDCYAEQVVARVARVCKGDMGGART
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEPHFVGSAYVPESVGSFTGDDDKVYFFFRERAVESDCYAEQVVARVARVCKGDMGGART
260 270 280 290 300 310
280 290 300 310 320 330
pF1KA1 LQRKWTTFLKARLACSAPNWQLYFNQLQAMHTLQDTSWHNTTFFGVFQAQWGDMYLSAIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQRKWTTFLKARLACSAPNWQLYFNQLQAMHTLQDTSWHNTTFFGVFQAQWGDMYLSAIC
320 330 340 350 360 370
340 350 360 370 380 390
pF1KA1 EYQLEEIQRVFEGPYKEYHEEAQKWDRYTDPVPSPRPGSCINNWHRRHGYTSSLELPDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYQLEEIQRVFEGPYKEYHEEAQKWDRYTDPVPSPRPGSCINNWHRRHGYTSSLELPDNI
380 390 400 410 420 430
400 410 420 430 440 450
pF1KA1 LNFVKKHPLMEEQVGPRWSRPLLVKKGTNFTHLVADRVTGLDGATYTVLFIGTGDGWLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNFVKKHPLMEEQVGPRWSRPLLVKKGTNFTHLVADRVTGLDGATYTVLFIGTGDGWLLK
440 450 460 470 480 490
460 470 480 490 500 510
pF1KA1 AVSLGPWVHLIEELQLFDQEPMRSLVLSQSKKLLFAGSRSQLVQLPVADCMKYRSCADCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVSLGPWVHLIEELQLFDQEPMRSLVLSQSKKLLFAGSRSQLVQLPVADCMKYRSCADCV
500 510 520 530 540 550
520 530 540 550 560 570
pF1KA1 LARDPYCAWSVNTSRCVAVGGHSGSLLIQHVMTSDTSGICNLRGSKKVRPTPKNITVVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LARDPYCAWSVNTSRCVAVGGHSGSLLIQHVMTSDTSGICNLRGSKKVRPTPKNITVVAG
560 570 580 590 600 610
580 590 600 610 620 630
pF1KA1 TDLVLPCHLSSNLAHARWTFGGRDLPAEQPGSFLYDARLQALVVMAAQPRHAGAYHCFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDLVLPCHLSSNLAHARWTFGGRDLPAEQPGSFLYDARLQALVVMAAQPRHAGAYHCFSE
620 630 640 650 660 670
640 650 660 670 680 690
pF1KA1 EQGARLAAEGYLVAVVAGPSVTLEARAPLENLGLVWLAVVALGAVCLVLLLLVLSLRRRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQGARLAAEGYLVAVVAGPSVTLEARAPLENLGLVWLAVVALGAVCLVLLLLVLSLRRRL
680 690 700 710 720 730
700 710 720 730 740 750
pF1KA1 REELEKGAKATERTLVYPLELPKEPTSPPFRPCPEPDEKLWDPVGYYYSDGSLKIVPGHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REELEKGAKATERTLVYPLELPKEPTSPPFRPCPEPDEKLWDPVGYYYSDGSLKIVPGHA
740 750 760 770 780 790
760 770 780 790 800 810
pF1KA1 RCQPGGGPPSPPPGIPGQPLPSPTRLHLGGGRNSNANGYVRLQLGGEDRGGLGHPLPELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RCQPGGGPPSPPPGIPGQPLPSPTRLHLGGGRNSNANGYVRLQLGGEDRGGLGHPLPELA
800 810 820 830 840 850
820 830
pF1KA1 DELRRKLQQRQPLPDSNPEESSV
:::::::::::::::::::::::
XP_016 DELRRKLQQRQPLPDSNPEESSV
860 870
>>XP_016859883 (OMIM: 604462) PREDICTED: semaphorin-4C i (692 aa)
initn: 4804 init1: 4804 opt: 4804 Z-score: 3533.2 bits: 664.5 E(85289): 4.6e-190
Smith-Waterman score: 4804; 100.0% identity (100.0% similar) in 692 aa overlap (142-833:1-692)
120 130 140 150 160 170
pF1KA1 NFIRFLQPYNASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLL
::::::::::::::::::::::::::::::
XP_016 MLTFTLEHGEFEDGKGKCPYDPAKGHAGLL
10 20 30
180 190 200 210 220 230
pF1KA1 VDGELYSATLNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDGELYSATLNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGD
40 50 60 70 80 90
240 250 260 270 280 290
pF1KA1 DDKVYFFFRERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDKVYFFFRERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQ
100 110 120 130 140 150
300 310 320 330 340 350
pF1KA1 LYFNQLQAMHTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYFNQLQAMHTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEE
160 170 180 190 200 210
360 370 380 390 400 410
pF1KA1 AQKWDRYTDPVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQKWDRYTDPVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRP
220 230 240 250 260 270
420 430 440 450 460 470
pF1KA1 LLVKKGTNFTHLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLVKKGTNFTHLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEP
280 290 300 310 320 330
480 490 500 510 520 530
pF1KA1 MRSLVLSQSKKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRSLVLSQSKKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGG
340 350 360 370 380 390
540 550 560 570 580 590
pF1KA1 HSGSLLIQHVMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSGSLLIQHVMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFG
400 410 420 430 440 450
600 610 620 630 640 650
pF1KA1 GRDLPAEQPGSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRDLPAEQPGSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSV
460 470 480 490 500 510
660 670 680 690 700 710
pF1KA1 TLEARAPLENLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLEARAPLENLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLEL
520 530 540 550 560 570
720 730 740 750 760 770
pF1KA1 PKEPTSPPFRPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKEPTSPPFRPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLP
580 590 600 610 620 630
780 790 800 810 820 830
pF1KA1 SPTRLHLGGGRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPTRLHLGGGRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEES
640 650 660 670 680 690
pF1KA1 SV
::
XP_016 SV
>>XP_006712669 (OMIM: 604462) PREDICTED: semaphorin-4C i (495 aa)
initn: 3349 init1: 3349 opt: 3349 Z-score: 2468.6 bits: 467.0 E(85289): 9.2e-131
Smith-Waterman score: 3349; 99.8% identity (99.8% similar) in 483 aa overlap (1-483:1-483)
10 20 30 40 50 60
pF1KA1 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH
: :
XP_006 KTLQAVLWFWLWPLP
490
833 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 21:56:33 2016 done: Wed Nov 2 21:56:35 2016
Total Scan time: 13.360 Total Display time: 0.240
Function used was FASTA [36.3.4 Apr, 2011]