FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1739, 833 aa 1>>>pF1KA1739 833 - 833 aa - 833 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.0875+/-0.000374; mu= 3.5984+/- 0.023 mean_var=185.9941+/-37.228, 0's: 0 Z-trim(120.2): 195 B-trim: 687 in 1/54 Lambda= 0.094043 statistics sampled from 34965 (35162) to 34965 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.736), E-opt: 0.2 (0.412), width: 16 Scan time: 13.360 The best scores are: opt bits E(85289) XP_011509685 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 5771 795.7 0 XP_011509682 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 5771 795.7 0 XP_011509683 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 5771 795.7 0 NP_060259 (OMIM: 604462) semaphorin-4C precursor [ ( 833) 5771 795.7 0 XP_011509680 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 5771 795.7 0 XP_011509681 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 5771 795.7 0 XP_011509684 (OMIM: 604462) PREDICTED: semaphorin- ( 833) 5771 795.7 0 XP_016859882 (OMIM: 604462) PREDICTED: semaphorin- ( 875) 5771 795.7 0 XP_016859883 (OMIM: 604462) PREDICTED: semaphorin- ( 692) 4804 664.5 4.6e-190 XP_006712669 (OMIM: 604462) PREDICTED: semaphorin- ( 495) 3349 467.0 9.2e-131 XP_016869682 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63 XP_016869684 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63 XP_011516431 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63 XP_011516430 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63 XP_016869686 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63 XP_016869687 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63 XP_005251711 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63 XP_011516433 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63 NP_006369 (OMIM: 601866) semaphorin-4D isoform 1 p ( 862) 1700 243.4 3.3e-63 XP_016869683 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63 XP_011516432 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63 XP_011516436 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63 XP_011516425 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63 XP_011516426 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63 XP_011516429 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63 XP_011516435 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63 XP_011516427 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63 XP_016869685 (OMIM: 601866) PREDICTED: semaphorin- ( 862) 1700 243.4 3.3e-63 NP_001135759 (OMIM: 601866) semaphorin-4D isoform ( 738) 1636 234.7 1.2e-60 NP_001310961 (OMIM: 617029) semaphorin-4B isoform ( 602) 1622 232.7 3.7e-60 NP_064595 (OMIM: 617029) semaphorin-4B isoform 1 p ( 837) 1624 233.1 4.1e-60 NP_945119 (OMIM: 617029) semaphorin-4B isoform 1 p ( 837) 1624 233.1 4.1e-60 NP_001310960 (OMIM: 617029) semaphorin-4B isoform ( 890) 1624 233.1 4.3e-60 XP_016869688 (OMIM: 601866) PREDICTED: semaphorin- ( 534) 1418 205.0 7.2e-52 NP_001310963 (OMIM: 617029) semaphorin-4B isoform ( 847) 1410 204.0 2.3e-51 XP_011530777 (OMIM: 603706) PREDICTED: semaphorin- ( 624) 1395 201.9 7.2e-51 NP_004254 (OMIM: 603706) semaphorin-4F isoform 1 p ( 770) 1395 202.0 8.6e-51 XP_011530779 (OMIM: 603706) PREDICTED: semaphorin- ( 597) 1354 196.4 3.3e-49 XP_011530778 (OMIM: 603706) PREDICTED: semaphorin- ( 600) 1351 196.0 4.4e-49 NP_001310962 (OMIM: 617029) semaphorin-4B isoform ( 681) 1340 194.5 1.4e-48 NP_001310959 (OMIM: 617029) semaphorin-4B isoform ( 681) 1340 194.5 1.4e-48 XP_016858661 (OMIM: 603706) PREDICTED: semaphorin- ( 668) 1297 188.7 7.7e-47 XP_005265439 (OMIM: 601124) PREDICTED: semaphorin- ( 754) 1165 170.8 2.1e-41 NP_001305729 (OMIM: 601124) semaphorin-3F isoform ( 754) 1165 170.8 2.1e-41 NP_001305727 (OMIM: 601124) semaphorin-3F isoform ( 686) 1158 169.8 3.7e-41 XP_016858662 (OMIM: 603706) PREDICTED: semaphorin- ( 635) 1139 167.2 2.1e-40 NP_001258591 (OMIM: 603706) semaphorin-4F isoform ( 737) 1139 167.2 2.4e-40 NP_004627 (OMIM: 601281) semaphorin-3B isoform 1 p ( 749) 1132 166.3 4.6e-40 NP_001276989 (OMIM: 601281) semaphorin-3B isoform ( 749) 1132 166.3 4.6e-40 XP_005250168 (OMIM: 603961,614897) PREDICTED: sema ( 771) 1099 161.8 1.1e-38 >>XP_011509685 (OMIM: 604462) PREDICTED: semaphorin-4C i (833 aa) initn: 5771 init1: 5771 opt: 5771 Z-score: 4241.0 bits: 795.7 E(85289): 0 Smith-Waterman score: 5771; 100.0% identity (100.0% similar) in 833 aa overlap (1-833:1-833) 10 20 30 40 50 60 pF1KA1 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG 730 740 750 760 770 780 790 800 810 820 830 pF1KA1 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV 790 800 810 820 830 >>XP_011509682 (OMIM: 604462) PREDICTED: semaphorin-4C i (833 aa) initn: 5771 init1: 5771 opt: 5771 Z-score: 4241.0 bits: 795.7 E(85289): 0 Smith-Waterman score: 5771; 100.0% identity (100.0% similar) in 833 aa overlap (1-833:1-833) 10 20 30 40 50 60 pF1KA1 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG 730 740 750 760 770 780 790 800 810 820 830 pF1KA1 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV 790 800 810 820 830 >>XP_011509683 (OMIM: 604462) PREDICTED: semaphorin-4C i (833 aa) initn: 5771 init1: 5771 opt: 5771 Z-score: 4241.0 bits: 795.7 E(85289): 0 Smith-Waterman score: 5771; 100.0% identity (100.0% similar) in 833 aa overlap (1-833:1-833) 10 20 30 40 50 60 pF1KA1 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG 730 740 750 760 770 780 790 800 810 820 830 pF1KA1 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV 790 800 810 820 830 >>NP_060259 (OMIM: 604462) semaphorin-4C precursor [Homo (833 aa) initn: 5771 init1: 5771 opt: 5771 Z-score: 4241.0 bits: 795.7 E(85289): 0 Smith-Waterman score: 5771; 100.0% identity (100.0% similar) in 833 aa overlap (1-833:1-833) 10 20 30 40 50 60 pF1KA1 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG 730 740 750 760 770 780 790 800 810 820 830 pF1KA1 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV 790 800 810 820 830 >>XP_011509680 (OMIM: 604462) PREDICTED: semaphorin-4C i (833 aa) initn: 5771 init1: 5771 opt: 5771 Z-score: 4241.0 bits: 795.7 E(85289): 0 Smith-Waterman score: 5771; 100.0% identity (100.0% similar) in 833 aa overlap (1-833:1-833) 10 20 30 40 50 60 pF1KA1 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG 730 740 750 760 770 780 790 800 810 820 830 pF1KA1 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV 790 800 810 820 830 >>XP_011509681 (OMIM: 604462) PREDICTED: semaphorin-4C i (833 aa) initn: 5771 init1: 5771 opt: 5771 Z-score: 4241.0 bits: 795.7 E(85289): 0 Smith-Waterman score: 5771; 100.0% identity (100.0% similar) in 833 aa overlap (1-833:1-833) 10 20 30 40 50 60 pF1KA1 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG 730 740 750 760 770 780 790 800 810 820 830 pF1KA1 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV 790 800 810 820 830 >>XP_011509684 (OMIM: 604462) PREDICTED: semaphorin-4C i (833 aa) initn: 5771 init1: 5771 opt: 5771 Z-score: 4241.0 bits: 795.7 E(85289): 0 Smith-Waterman score: 5771; 100.0% identity (100.0% similar) in 833 aa overlap (1-833:1-833) 10 20 30 40 50 60 pF1KA1 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGG 730 740 750 760 770 780 790 800 810 820 830 pF1KA1 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV 790 800 810 820 830 >>XP_016859882 (OMIM: 604462) PREDICTED: semaphorin-4C i (875 aa) initn: 5771 init1: 5771 opt: 5771 Z-score: 4240.7 bits: 795.7 E(85289): 0 Smith-Waterman score: 5771; 100.0% identity (100.0% similar) in 833 aa overlap (1-833:43-875) 10 20 30 pF1KA1 MAPHWAVWLLAARLWGLGIGAEVWWNLVPR :::::::::::::::::::::::::::::: XP_016 SGLLSLAVISDHVFSLSRTAGLKLRAGACAMAPHWAVWLLAARLWGLGIGAEVWWNLVPR 20 30 40 50 60 70 40 50 60 70 80 90 pF1KA1 KTVSSGELATVVRRFSQTGIQDFLTLTLTEPTGLLYVGAREALFAFSMEALELQGAISWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTVSSGELATVVRRFSQTGIQDFLTLTLTEPTGLLYVGAREALFAFSMEALELQGAISWE 80 90 100 110 120 130 100 110 120 130 140 150 pF1KA1 APVEKKTECIQKGKNNQTECFNFIRFLQPYNASHLYVCGTYAFQPKCTYVNMLTFTLEHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APVEKKTECIQKGKNNQTECFNFIRFLQPYNASHLYVCGTYAFQPKCTYVNMLTFTLEHG 140 150 160 170 180 190 160 170 180 190 200 210 pF1KA1 EFEDGKGKCPYDPAKGHAGLLVDGELYSATLNNFLGTEPIILRNMGPHHSMKTEYLAFWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFEDGKGKCPYDPAKGHAGLLVDGELYSATLNNFLGTEPIILRNMGPHHSMKTEYLAFWL 200 210 220 230 240 250 220 230 240 250 260 270 pF1KA1 NEPHFVGSAYVPESVGSFTGDDDKVYFFFRERAVESDCYAEQVVARVARVCKGDMGGART :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEPHFVGSAYVPESVGSFTGDDDKVYFFFRERAVESDCYAEQVVARVARVCKGDMGGART 260 270 280 290 300 310 280 290 300 310 320 330 pF1KA1 LQRKWTTFLKARLACSAPNWQLYFNQLQAMHTLQDTSWHNTTFFGVFQAQWGDMYLSAIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQRKWTTFLKARLACSAPNWQLYFNQLQAMHTLQDTSWHNTTFFGVFQAQWGDMYLSAIC 320 330 340 350 360 370 340 350 360 370 380 390 pF1KA1 EYQLEEIQRVFEGPYKEYHEEAQKWDRYTDPVPSPRPGSCINNWHRRHGYTSSLELPDNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EYQLEEIQRVFEGPYKEYHEEAQKWDRYTDPVPSPRPGSCINNWHRRHGYTSSLELPDNI 380 390 400 410 420 430 400 410 420 430 440 450 pF1KA1 LNFVKKHPLMEEQVGPRWSRPLLVKKGTNFTHLVADRVTGLDGATYTVLFIGTGDGWLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNFVKKHPLMEEQVGPRWSRPLLVKKGTNFTHLVADRVTGLDGATYTVLFIGTGDGWLLK 440 450 460 470 480 490 460 470 480 490 500 510 pF1KA1 AVSLGPWVHLIEELQLFDQEPMRSLVLSQSKKLLFAGSRSQLVQLPVADCMKYRSCADCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVSLGPWVHLIEELQLFDQEPMRSLVLSQSKKLLFAGSRSQLVQLPVADCMKYRSCADCV 500 510 520 530 540 550 520 530 540 550 560 570 pF1KA1 LARDPYCAWSVNTSRCVAVGGHSGSLLIQHVMTSDTSGICNLRGSKKVRPTPKNITVVAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LARDPYCAWSVNTSRCVAVGGHSGSLLIQHVMTSDTSGICNLRGSKKVRPTPKNITVVAG 560 570 580 590 600 610 580 590 600 610 620 630 pF1KA1 TDLVLPCHLSSNLAHARWTFGGRDLPAEQPGSFLYDARLQALVVMAAQPRHAGAYHCFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDLVLPCHLSSNLAHARWTFGGRDLPAEQPGSFLYDARLQALVVMAAQPRHAGAYHCFSE 620 630 640 650 660 670 640 650 660 670 680 690 pF1KA1 EQGARLAAEGYLVAVVAGPSVTLEARAPLENLGLVWLAVVALGAVCLVLLLLVLSLRRRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQGARLAAEGYLVAVVAGPSVTLEARAPLENLGLVWLAVVALGAVCLVLLLLVLSLRRRL 680 690 700 710 720 730 700 710 720 730 740 750 pF1KA1 REELEKGAKATERTLVYPLELPKEPTSPPFRPCPEPDEKLWDPVGYYYSDGSLKIVPGHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REELEKGAKATERTLVYPLELPKEPTSPPFRPCPEPDEKLWDPVGYYYSDGSLKIVPGHA 740 750 760 770 780 790 760 770 780 790 800 810 pF1KA1 RCQPGGGPPSPPPGIPGQPLPSPTRLHLGGGRNSNANGYVRLQLGGEDRGGLGHPLPELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RCQPGGGPPSPPPGIPGQPLPSPTRLHLGGGRNSNANGYVRLQLGGEDRGGLGHPLPELA 800 810 820 830 840 850 820 830 pF1KA1 DELRRKLQQRQPLPDSNPEESSV ::::::::::::::::::::::: XP_016 DELRRKLQQRQPLPDSNPEESSV 860 870 >>XP_016859883 (OMIM: 604462) PREDICTED: semaphorin-4C i (692 aa) initn: 4804 init1: 4804 opt: 4804 Z-score: 3533.2 bits: 664.5 E(85289): 4.6e-190 Smith-Waterman score: 4804; 100.0% identity (100.0% similar) in 692 aa overlap (142-833:1-692) 120 130 140 150 160 170 pF1KA1 NFIRFLQPYNASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLL :::::::::::::::::::::::::::::: XP_016 MLTFTLEHGEFEDGKGKCPYDPAKGHAGLL 10 20 30 180 190 200 210 220 230 pF1KA1 VDGELYSATLNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDGELYSATLNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGD 40 50 60 70 80 90 240 250 260 270 280 290 pF1KA1 DDKVYFFFRERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDKVYFFFRERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQ 100 110 120 130 140 150 300 310 320 330 340 350 pF1KA1 LYFNQLQAMHTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYFNQLQAMHTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEE 160 170 180 190 200 210 360 370 380 390 400 410 pF1KA1 AQKWDRYTDPVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQKWDRYTDPVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRP 220 230 240 250 260 270 420 430 440 450 460 470 pF1KA1 LLVKKGTNFTHLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLVKKGTNFTHLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEP 280 290 300 310 320 330 480 490 500 510 520 530 pF1KA1 MRSLVLSQSKKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MRSLVLSQSKKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGG 340 350 360 370 380 390 540 550 560 570 580 590 pF1KA1 HSGSLLIQHVMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSGSLLIQHVMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFG 400 410 420 430 440 450 600 610 620 630 640 650 pF1KA1 GRDLPAEQPGSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRDLPAEQPGSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSV 460 470 480 490 500 510 660 670 680 690 700 710 pF1KA1 TLEARAPLENLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLEARAPLENLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLEL 520 530 540 550 560 570 720 730 740 750 760 770 pF1KA1 PKEPTSPPFRPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKEPTSPPFRPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLP 580 590 600 610 620 630 780 790 800 810 820 830 pF1KA1 SPTRLHLGGGRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPTRLHLGGGRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEES 640 650 660 670 680 690 pF1KA1 SV :: XP_016 SV >>XP_006712669 (OMIM: 604462) PREDICTED: semaphorin-4C i (495 aa) initn: 3349 init1: 3349 opt: 3349 Z-score: 2468.6 bits: 467.0 E(85289): 9.2e-131 Smith-Waterman score: 3349; 99.8% identity (99.8% similar) in 483 aa overlap (1-483:1-483) 10 20 30 40 50 60 pF1KA1 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSAT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 THLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 KKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQH : : XP_006 KTLQAVLWFWLWPLP 490 833 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 21:56:33 2016 done: Wed Nov 2 21:56:35 2016 Total Scan time: 13.360 Total Display time: 0.240 Function used was FASTA [36.3.4 Apr, 2011]