FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1741, 1729 aa 1>>>pF1KA1741 1729 - 1729 aa - 1729 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.3012+/-0.000474; mu= -17.5936+/- 0.029 mean_var=588.1639+/-122.007, 0's: 0 Z-trim(123.0): 16 B-trim: 0 in 0/58 Lambda= 0.052884 statistics sampled from 42042 (42061) to 42042 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.764), E-opt: 0.2 (0.493), width: 16 Scan time: 22.560 The best scores are: opt bits E(85289) NP_203754 (OMIM: 607104) 182 kDa tankyrase-1-bindi (1729) 11842 920.1 0 XP_006718788 (OMIM: 607104) PREDICTED: 182 kDa tan (1729) 11842 920.1 0 XP_011543627 (OMIM: 607104) PREDICTED: 182 kDa tan (1480) 9915 773.0 0 >>NP_203754 (OMIM: 607104) 182 kDa tankyrase-1-binding p (1729 aa) initn: 11842 init1: 11842 opt: 11842 Z-score: 4901.7 bits: 920.1 E(85289): 0 Smith-Waterman score: 11842; 100.0% identity (100.0% similar) in 1729 aa overlap (1-1729:1-1729) 10 20 30 40 50 60 pF1KA1 MKVSTLRESSAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 MKVSTLRESSAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 VPVGPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 VPVGPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 EAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 EAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 RLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 RLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 EERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 EERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 SPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 APEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 APEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 TSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 TSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 PTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 PTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 SWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 SPLPLATREAALPILEPVLGQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARAETTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 SPLPLATREAALPILEPVLGQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARAETTQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 ARTEAQDLCRASPEPPGPESSSRWLDDLLASPPPSGGGARRGAGAELKDTQSPSTCSEGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 ARTEAQDLCRASPEPPGPESSSRWLDDLLASPPPSGGGARRGAGAELKDTQSPSTCSEGL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 LGWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQDYGLGGASPRGDPGLGERDWTSKYGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 LGWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQDYGLGGASPRGDPGLGERDWTSKYGQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 GAGEGSTREWASRCGIGQEEMEASSSQDQSKVSAPGVLTAQDRVVGKPAQLGTQRSQEAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 GAGEGSTREWASRCGIGQEEMEASSSQDQSKVSAPGVLTAQDRVVGKPAQLGTQRSQEAD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 VQDWEFRKRDSQGTYSSRDAELQDQEFGKRDSLGTYSSRDVSLGDWEFGKRDSLGAYASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 VQDWEFRKRDSQGTYSSRDAELQDQEFGKRDSLGTYSSRDVSLGDWEFGKRDSLGAYASQ 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 DANEQGQDLGKRDHHGRYSSQDADEQDWEFQKRDVSLGTYGSRAAEPQEQEFGKSAWIRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 DANEQGQDLGKRDHHGRYSSQDADEQDWEFQKRDVSLGTYGSRAAEPQEQEFGKSAWIRD 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 YSSGGSSRTLDAQDRSFGTRPLSSGFSPEEAQQQDEEFEKKIPSVEDSLGEGSRDAGRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 YSSGGSSRTLDAQDRSFGTRPLSSGFSPEEAQQQDEEFEKKIPSVEDSLGEGSRDAGRPG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 ERGSGGLFSPSTAHVPDGALGQRDQSSWQNSDASQEVGGHQERQQAGAQGPGSADLEDGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 ERGSGGLFSPSTAHVPDGALGQRDQSSWQNSDASQEVGGHQERQQAGAQGPGSADLEDGE 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 MGKRGWVGEFSLSVGPQREAAFSPGQQDWSRDFCIEASERSYQFGIIGNDRVSGAGFSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 MGKRGWVGEFSLSVGPQREAAFSPGQQDWSRDFCIEASERSYQFGIIGNDRVSGAGFSPS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 SKMEGGHFVPPGKTTAGSVDWTDQLGLRNLEVSSCVGSGGSSEARESAVGQMGWSGGLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 SKMEGGHFVPPGKTTAGSVDWTDQLGLRNLEVSSCVGSGGSSEARESAVGQMGWSGGLSL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 RDMNLTGCLESGGSEEPGGIGVGEKDWTSDVNVKSKDLAEVGEGGGHSQARESGVGQTDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 RDMNLTGCLESGGSEEPGGIGVGEKDWTSDVNVKSKDLAEVGEGGGHSQARESGVGQTDW 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 SGVEAGEFLKSRERGVGQADWTPDLGLRNMAPGAVCSPGESKELGVGQMDWGNNLGLRDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 SGVEAGEFLKSRERGVGQADWTPDLGLRNMAPGAVCSPGESKELGVGQMDWGNNLGLRDL 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA1 EVTCDPDSGGSQGLRGCGVGQMDWTQDLAPQNVELFGAPSEAREHGVGGVSQCPEPGLRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 EVTCDPDSGGSQGLRGCGVGQMDWTQDLAPQNVELFGAPSEAREHGVGGVSQCPEPGLRH 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA1 NGSLSPGLEARDPLEARELGVGETSGPETQGEDYSSSSLEPHPADPGMETGEALSFGASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 NGSLSPGLEARDPLEARELGVGETSGPETQGEDYSSSSLEPHPADPGMETGEALSFGASP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA1 GRCPARPPPSGSQGLLEEMLAASSSKAVARRESAASGLGGLLEEEGAGAGAAQEEVLEPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 GRCPARPPPSGSQGLLEEMLAASSSKAVARRESAASGLGGLLEEEGAGAGAAQEEVLEPG 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA1 RDSPPSWRPQPDGEASQTEDVDGTWGSSAARWSDQGPAQTSRRPSQGPPARSPSQDFSFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 RDSPPSWRPQPDGEASQTEDVDGTWGSSAARWSDQGPAQTSRRPSQGPPARSPSQDFSFI 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA1 EDTEILDSAMYRSRANLGRKRGHRAPVIRPGGTLGLSEAADSDAHLFQDSTEPRASRVPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 EDTEILDSAMYRSRANLGRKRGHRAPVIRPGGTLGLSEAADSDAHLFQDSTEPRASRVPS 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA1 SDEEVVEEPQSRRTRMSLGTKGLKVNLFPGLSPSALKAKLRPRNRSAEEGELAESKSSQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 SDEEVVEEPQSRRTRMSLGTKGLKVNLFPGLSPSALKAKLRPRNRSAEEGELAESKSSQK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 pF1KA1 ESAVQRSKSCKVPGLGKPLTLPPKPEKSSGSEGSSPNWLQALKLKKKKV ::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 ESAVQRSKSCKVPGLGKPLTLPPKPEKSSGSEGSSPNWLQALKLKKKKV 1690 1700 1710 1720 >>XP_006718788 (OMIM: 607104) PREDICTED: 182 kDa tankyra (1729 aa) initn: 11842 init1: 11842 opt: 11842 Z-score: 4901.7 bits: 920.1 E(85289): 0 Smith-Waterman score: 11842; 100.0% identity (100.0% similar) in 1729 aa overlap (1-1729:1-1729) 10 20 30 40 50 60 pF1KA1 MKVSTLRESSAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MKVSTLRESSAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 VPVGPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VPVGPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 EAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 RLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 EERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 APEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 APEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 TSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 PTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 SPLPLATREAALPILEPVLGQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARAETTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SPLPLATREAALPILEPVLGQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARAETTQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 ARTEAQDLCRASPEPPGPESSSRWLDDLLASPPPSGGGARRGAGAELKDTQSPSTCSEGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ARTEAQDLCRASPEPPGPESSSRWLDDLLASPPPSGGGARRGAGAELKDTQSPSTCSEGL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 LGWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQDYGLGGASPRGDPGLGERDWTSKYGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQDYGLGGASPRGDPGLGERDWTSKYGQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 GAGEGSTREWASRCGIGQEEMEASSSQDQSKVSAPGVLTAQDRVVGKPAQLGTQRSQEAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GAGEGSTREWASRCGIGQEEMEASSSQDQSKVSAPGVLTAQDRVVGKPAQLGTQRSQEAD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 VQDWEFRKRDSQGTYSSRDAELQDQEFGKRDSLGTYSSRDVSLGDWEFGKRDSLGAYASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VQDWEFRKRDSQGTYSSRDAELQDQEFGKRDSLGTYSSRDVSLGDWEFGKRDSLGAYASQ 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 DANEQGQDLGKRDHHGRYSSQDADEQDWEFQKRDVSLGTYGSRAAEPQEQEFGKSAWIRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DANEQGQDLGKRDHHGRYSSQDADEQDWEFQKRDVSLGTYGSRAAEPQEQEFGKSAWIRD 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 YSSGGSSRTLDAQDRSFGTRPLSSGFSPEEAQQQDEEFEKKIPSVEDSLGEGSRDAGRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YSSGGSSRTLDAQDRSFGTRPLSSGFSPEEAQQQDEEFEKKIPSVEDSLGEGSRDAGRPG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 ERGSGGLFSPSTAHVPDGALGQRDQSSWQNSDASQEVGGHQERQQAGAQGPGSADLEDGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ERGSGGLFSPSTAHVPDGALGQRDQSSWQNSDASQEVGGHQERQQAGAQGPGSADLEDGE 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 MGKRGWVGEFSLSVGPQREAAFSPGQQDWSRDFCIEASERSYQFGIIGNDRVSGAGFSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MGKRGWVGEFSLSVGPQREAAFSPGQQDWSRDFCIEASERSYQFGIIGNDRVSGAGFSPS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 SKMEGGHFVPPGKTTAGSVDWTDQLGLRNLEVSSCVGSGGSSEARESAVGQMGWSGGLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SKMEGGHFVPPGKTTAGSVDWTDQLGLRNLEVSSCVGSGGSSEARESAVGQMGWSGGLSL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 RDMNLTGCLESGGSEEPGGIGVGEKDWTSDVNVKSKDLAEVGEGGGHSQARESGVGQTDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RDMNLTGCLESGGSEEPGGIGVGEKDWTSDVNVKSKDLAEVGEGGGHSQARESGVGQTDW 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 SGVEAGEFLKSRERGVGQADWTPDLGLRNMAPGAVCSPGESKELGVGQMDWGNNLGLRDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGVEAGEFLKSRERGVGQADWTPDLGLRNMAPGAVCSPGESKELGVGQMDWGNNLGLRDL 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA1 EVTCDPDSGGSQGLRGCGVGQMDWTQDLAPQNVELFGAPSEAREHGVGGVSQCPEPGLRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EVTCDPDSGGSQGLRGCGVGQMDWTQDLAPQNVELFGAPSEAREHGVGGVSQCPEPGLRH 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA1 NGSLSPGLEARDPLEARELGVGETSGPETQGEDYSSSSLEPHPADPGMETGEALSFGASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NGSLSPGLEARDPLEARELGVGETSGPETQGEDYSSSSLEPHPADPGMETGEALSFGASP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA1 GRCPARPPPSGSQGLLEEMLAASSSKAVARRESAASGLGGLLEEEGAGAGAAQEEVLEPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GRCPARPPPSGSQGLLEEMLAASSSKAVARRESAASGLGGLLEEEGAGAGAAQEEVLEPG 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA1 RDSPPSWRPQPDGEASQTEDVDGTWGSSAARWSDQGPAQTSRRPSQGPPARSPSQDFSFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RDSPPSWRPQPDGEASQTEDVDGTWGSSAARWSDQGPAQTSRRPSQGPPARSPSQDFSFI 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA1 EDTEILDSAMYRSRANLGRKRGHRAPVIRPGGTLGLSEAADSDAHLFQDSTEPRASRVPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EDTEILDSAMYRSRANLGRKRGHRAPVIRPGGTLGLSEAADSDAHLFQDSTEPRASRVPS 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA1 SDEEVVEEPQSRRTRMSLGTKGLKVNLFPGLSPSALKAKLRPRNRSAEEGELAESKSSQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SDEEVVEEPQSRRTRMSLGTKGLKVNLFPGLSPSALKAKLRPRNRSAEEGELAESKSSQK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 pF1KA1 ESAVQRSKSCKVPGLGKPLTLPPKPEKSSGSEGSSPNWLQALKLKKKKV ::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ESAVQRSKSCKVPGLGKPLTLPPKPEKSSGSEGSSPNWLQALKLKKKKV 1690 1700 1710 1720 >>XP_011543627 (OMIM: 607104) PREDICTED: 182 kDa tankyra (1480 aa) initn: 9912 init1: 9912 opt: 9915 Z-score: 4108.0 bits: 773.0 E(85289): 0 Smith-Waterman score: 9915; 98.6% identity (98.8% similar) in 1468 aa overlap (1-1461:1-1468) 10 20 30 40 50 60 pF1KA1 MKVSTLRESSAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKVSTLRESSAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 VPVGPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPVGPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 EAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 RLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 EERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 APEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 TSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 PTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 SPLPLATREAALPILEPVLGQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARAETTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPLPLATREAALPILEPVLGQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARAETTQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 ARTEAQDLCRASPEPPGPESSSRWLDDLLASPPPSGGGARRGAGAELKDTQSPSTCSEGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARTEAQDLCRASPEPPGPESSSRWLDDLLASPPPSGGGARRGAGAELKDTQSPSTCSEGL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 LGWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQDYGLGGASPRGDPGLGERDWTSKYGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQDYGLGGASPRGDPGLGERDWTSKYGQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 GAGEGSTREWASRCGIGQEEMEASSSQDQSKVSAPGVLTAQDRVVGKPAQLGTQRSQEAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GAGEGSTREWASRCGIGQEEMEASSSQDQSKVSAPGVLTAQDRVVGKPAQLGTQRSQEAD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 VQDWEFRKRDSQGTYSSRDAELQDQEFGKRDSLGTYSSRDVSLGDWEFGKRDSLGAYASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VQDWEFRKRDSQGTYSSRDAELQDQEFGKRDSLGTYSSRDVSLGDWEFGKRDSLGAYASQ 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 DANEQGQDLGKRDHHGRYSSQDADEQDWEFQKRDVSLGTYGSRAAEPQEQEFGKSAWIRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DANEQGQDLGKRDHHGRYSSQDADEQDWEFQKRDVSLGTYGSRAAEPQEQEFGKSAWIRD 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 YSSGGSSRTLDAQDRSFGTRPLSSGFSPEEAQQQDEEFEKKIPSVEDSLGEGSRDAGRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YSSGGSSRTLDAQDRSFGTRPLSSGFSPEEAQQQDEEFEKKIPSVEDSLGEGSRDAGRPG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 ERGSGGLFSPSTAHVPDGALGQRDQSSWQNSDASQEVGGHQERQQAGAQGPGSADLEDGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERGSGGLFSPSTAHVPDGALGQRDQSSWQNSDASQEVGGHQERQQAGAQGPGSADLEDGE 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 MGKRGWVGEFSLSVGPQREAAFSPGQQDWSRDFCIEASERSYQFGIIGNDRVSGAGFSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGKRGWVGEFSLSVGPQREAAFSPGQQDWSRDFCIEASERSYQFGIIGNDRVSGAGFSPS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 SKMEGGHFVPPGKTTAGSVDWTDQLGLRNLEVSSCVGSGGSSEARESAVGQMGWSGGLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKMEGGHFVPPGKTTAGSVDWTDQLGLRNLEVSSCVGSGGSSEARESAVGQMGWSGGLSL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 RDMNLTGCLESGGSEEPGGIGVGEKDWTSDVNVKSKDLAEVGEGGGHSQARESGVGQTDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDMNLTGCLESGGSEEPGGIGVGEKDWTSDVNVKSKDLAEVGEGGGHSQARESGVGQTDW 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 SGVEAGEFLKSRERGVGQADWTPDLGLRNMAPGAVCSPGESKELGVGQMDWGNNLGLRDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGVEAGEFLKSRERGVGQADWTPDLGLRNMAPGAVCSPGESKELGVGQMDWGNNLGLRDL 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA1 EVTCDPDSGGSQGLRGCGVGQMDWTQDLAPQNVELFGAPSEAREHGVGGVSQCPEPGLRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVTCDPDSGGSQGLRGCGVGQMDWTQDLAPQNVELFGAPSEAREHGVGGVSQCPEPGLRH 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA1 NGSLSPGLEARDPLEARELGVGETSGPETQGEDYSSSSLEPHPADPGMETGEALSFGASP ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGSLSPGLEARDPLEARELGVGETSGPETQGEDYSSSSLEPHPADPGMETGEALSFGASD 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 pF1KA1 GRCPARP---PPSG----SQGLLEEMLAASSSKAVARRESAASGLGGLLEEEGAGAGAAQ . .: : : :::. :: XP_011 SVQLEEPELFPGEGAHPRSQGFEPARLAQLFTCVLCCSRP 1450 1460 1470 1480 1729 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 21:57:19 2016 done: Wed Nov 2 21:57:22 2016 Total Scan time: 22.560 Total Display time: 0.350 Function used was FASTA [36.3.4 Apr, 2011]