Result of FASTA (omim) for
pF1KA1757
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1757, 1331 aa
1>>>pF1KA1757 1331 - 1331 aa - 1331 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.5630+/-0.000406; mu= -5.8282+/- 0.025
mean_var=334.7662+/-67.262, 0's: 0 Z-trim(122.3): 54 B-trim: 102 in 1/60
Lambda= 0.070098
statistics sampled from 40208 (40279) to 40208 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.761), E-opt: 0.2 (0.472), width: 16
Scan time: 19.500
The best scores are: opt bits E(85289)
NP_001073986 (OMIM: 615743,615761) SET domain-cont (1442) 8855 910.4 0
XP_016862264 (OMIM: 615743,615761) PREDICTED: SET (1449) 8855 910.4 0
XP_005265358 (OMIM: 615743,615761) PREDICTED: SET (1461) 8855 910.4 0
XP_016862261 (OMIM: 615743,615761) PREDICTED: SET (1468) 8855 910.4 0
NP_001278972 (OMIM: 615743,615761) SET domain-cont (1344) 8394 863.7 0
XP_016862270 (OMIM: 615743,615761) PREDICTED: SET (1344) 8394 863.7 0
XP_016862259 (OMIM: 615743,615761) PREDICTED: SET (1481) 8394 863.8 0
XP_016862269 (OMIM: 615743,615761) PREDICTED: SET (1350) 5381 559.0 7.9e-158
XP_011532234 (OMIM: 615743,615761) PREDICTED: SET (1350) 5381 559.0 7.9e-158
XP_011532235 (OMIM: 615743,615761) PREDICTED: SET (1350) 5381 559.0 7.9e-158
XP_016862268 (OMIM: 615743,615761) PREDICTED: SET (1350) 5381 559.0 7.9e-158
XP_005265360 (OMIM: 615743,615761) PREDICTED: SET (1442) 5381 559.0 8.4e-158
XP_016862263 (OMIM: 615743,615761) PREDICTED: SET (1461) 5381 559.1 8.5e-158
XP_016862262 (OMIM: 615743,615761) PREDICTED: SET (1468) 5381 559.1 8.5e-158
XP_016862260 (OMIM: 615743,615761) PREDICTED: SET (1480) 5381 559.1 8.6e-158
XP_016862258 (OMIM: 615743,615761) PREDICTED: SET (1487) 5381 559.1 8.6e-158
XP_016862267 (OMIM: 615743,615761) PREDICTED: SET (1363) 4920 512.4 8.7e-144
XP_016862266 (OMIM: 615743,615761) PREDICTED: SET (1363) 4920 512.4 8.7e-144
XP_016862265 (OMIM: 615743,615761) PREDICTED: SET (1363) 4920 512.4 8.7e-144
XP_011532232 (OMIM: 615743,615761) PREDICTED: SET (1455) 4920 512.4 9.1e-144
XP_011532230 (OMIM: 615743,615761) PREDICTED: SET (1474) 4920 512.4 9.2e-144
XP_011532229 (OMIM: 615743,615761) PREDICTED: SET (1481) 4920 512.4 9.3e-144
XP_011532224 (OMIM: 615743,615761) PREDICTED: SET (1493) 4920 512.4 9.3e-144
XP_016862257 (OMIM: 615743,615761) PREDICTED: SET (1493) 4920 512.4 9.3e-144
XP_011532223 (OMIM: 615743,615761) PREDICTED: SET (1500) 4920 512.4 9.4e-144
XP_011532222 (OMIM: 615743,615761) PREDICTED: SET (1500) 4920 512.4 9.4e-144
XP_016862256 (OMIM: 615743,615761) PREDICTED: SET (1500) 4920 512.4 9.4e-144
XP_016862272 (OMIM: 615743,615761) PREDICTED: SET (1274) 4890 509.4 6.7e-143
XP_016862271 (OMIM: 615743,615761) PREDICTED: SET (1305) 4823 502.6 7.5e-141
XP_016862273 (OMIM: 615743,615761) PREDICTED: SET ( 975) 4814 501.6 1.1e-140
XP_016862274 (OMIM: 615743,615761) PREDICTED: SET ( 842) 3988 418.0 1.4e-115
XP_016862275 (OMIM: 615743,615761) PREDICTED: SET ( 828) 3965 415.7 6.8e-115
XP_016867924 (OMIM: 608444) PREDICTED: histone-lys (1712) 998 115.8 2.6e-24
NP_891847 (OMIM: 608444) histone-lysine N-methyltr (1858) 998 115.9 2.8e-24
NP_061152 (OMIM: 608444) histone-lysine N-methyltr (1858) 998 115.9 2.8e-24
XP_011514702 (OMIM: 608444) PREDICTED: histone-lys (1858) 998 115.9 2.8e-24
XP_005250550 (OMIM: 608444) PREDICTED: histone-lys (1858) 998 115.9 2.8e-24
>>NP_001073986 (OMIM: 615743,615761) SET domain-containi (1442 aa)
initn: 8855 init1: 8855 opt: 8855 Z-score: 4852.8 bits: 910.4 E(85289): 0
Smith-Waterman score: 8855; 100.0% identity (100.0% similar) in 1331 aa overlap (1-1331:112-1442)
10 20 30
pF1KA1 MSRGKVIRLHRRKQDNISGGDSSATESWDE
::::::::::::::::::::::::::::::
NP_001 PNSEGETVPTWCPCGLSQDGFLLNCDKCRGMSRGKVIRLHRRKQDNISGGDSSATESWDE
90 100 110 120 130 140
40 50 60 70 80 90
pF1KA1 ELSPSTVLYTATQHTPTSITLTVRRTKPKKRKKSPEKGRAAPKTKKIKNSPSEAQNLDEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELSPSTVLYTATQHTPTSITLTVRRTKPKKRKKSPEKGRAAPKTKKIKNSPSEAQNLDEN
150 160 170 180 190 200
100 110 120 130 140 150
pF1KA1 TTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSSKEFVGKPTILDTINKTELACN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSSKEFVGKPTILDTINKTELACN
210 220 230 240 250 260
160 170 180 190 200 210
pF1KA1 NTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKP
270 280 290 300 310 320
220 230 240 250 260 270
pF1KA1 YPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITK
330 340 350 360 370 380
280 290 300 310 320 330
pF1KA1 DAEVTIAFDYEYSNCNYKVDCACHKGNRNCPIQKRNPNATELPLLPPPPSLPTIGAETRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAEVTIAFDYEYSNCNYKVDCACHKGNRNCPIQKRNPNATELPLLPPPPSLPTIGAETRR
390 400 410 420 430 440
340 350 360 370 380 390
pF1KA1 RKARRKELEMEQQNEASEENNDQQSQEVPEKVTVSSDHEEVDNPEEKPEEEKEEVIDDQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKARRKELEMEQQNEASEENNDQQSQEVPEKVTVSSDHEEVDNPEEKPEEEKEEVIDDQE
450 460 470 480 490 500
400 410 420 430 440 450
pF1KA1 NLAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPLEQSNSDVEITTTTSETPVGEETKTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPLEQSNSDVEITTTTSETPVGEETKTE
510 520 530 540 550 560
460 470 480 490 500 510
pF1KA1 APESEVSNSVSNVTIPSTPQSVGVNTRRSSQAGDIAAEKLVPKPPPAKPSRPRPKSRISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APESEVSNSVSNVTIPSTPQSVGVNTRRSSQAGDIAAEKLVPKPPPAKPSRPRPKSRISR
570 580 590 600 610 620
520 530 540 550 560 570
pF1KA1 YRTSSAQRLKRQKQANAQQAELSQAALEEGGSNSLVTPTEAGSLDSSGENRPLTGSDPTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YRTSSAQRLKRQKQANAQQAELSQAALEEGGSNSLVTPTEAGSLDSSGENRPLTGSDPTV
630 640 650 660 670 680
580 590 600 610 620 630
pF1KA1 VSITGSHVNRAASKYPKTKKYLVTEWLNDKAEKQECPVECPLRITTDPTVLATTLNMLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSITGSHVNRAASKYPKTKKYLVTEWLNDKAEKQECPVECPLRITTDPTVLATTLNMLPG
690 700 710 720 730 740
640 650 660 670 680 690
pF1KA1 LIHSPLICTTPKHYIRFGSPFIPERRRRPLLPDGTFSSCKKRWIKQALEEGMTQTSSVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIHSPLICTTPKHYIRFGSPFIPERRRRPLLPDGTFSSCKKRWIKQALEEGMTQTSSVPQ
750 760 770 780 790 800
700 710 720 730 740 750
pF1KA1 ETRTQHLYQSNENSSSSSICKDNADLLSPLKKWKSRYLMEQNVTKLLRPLSPVTPPPPNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETRTQHLYQSNENSSSSSICKDNADLLSPLKKWKSRYLMEQNVTKLLRPLSPVTPPPPNS
810 820 830 840 850 860
760 770 780 790 800 810
pF1KA1 GSKSPQLATPGSSHPGEEECRNGYSLMFSPVTSLTTASRCNTPLQFELCHRKDLDLAKVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSKSPQLATPGSSHPGEEECRNGYSLMFSPVTSLTTASRCNTPLQFELCHRKDLDLAKVG
870 880 890 900 910 920
820 830 840 850 860 870
pF1KA1 YLDSNTNSCADRPSLLNSGHSDLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLDSNTNSCADRPSLLNSGHSDLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEF
930 940 950 960 970 980
880 890 900 910 920 930
pF1KA1 NLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGS
990 1000 1010 1020 1030 1040
940 950 960 970 980 990
pF1KA1 LSPGGERACEGVPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSPGGERACEGVPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQ
1050 1060 1070 1080 1090 1100
1000 1010 1020 1030 1040 1050
pF1KA1 GSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQEN
1110 1120 1130 1140 1150 1160
1060 1070 1080 1090 1100 1110
pF1KA1 ISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETL
1170 1180 1190 1200 1210 1220
1120 1130 1140 1150 1160 1170
pF1KA1 SSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRP
1230 1240 1250 1260 1270 1280
1180 1190 1200 1210 1220 1230
pF1KA1 GNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCP
1290 1300 1310 1320 1330 1340
1240 1250 1260 1270 1280 1290
pF1KA1 SSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQ
1350 1360 1370 1380 1390 1400
1300 1310 1320 1330
pF1KA1 ASRVSAVSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQTGLS
:::::::::::::::::::::::::::::::::::::::::
NP_001 ASRVSAVSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQTGLS
1410 1420 1430 1440
>>XP_016862264 (OMIM: 615743,615761) PREDICTED: SET doma (1449 aa)
initn: 8855 init1: 8855 opt: 8855 Z-score: 4852.7 bits: 910.4 E(85289): 0
Smith-Waterman score: 8855; 100.0% identity (100.0% similar) in 1331 aa overlap (1-1331:119-1449)
10 20 30
pF1KA1 MSRGKVIRLHRRKQDNISGGDSSATESWDE
::::::::::::::::::::::::::::::
XP_016 PNSEGETVPTWCPCGLSQDGFLLNCDKCRGMSRGKVIRLHRRKQDNISGGDSSATESWDE
90 100 110 120 130 140
40 50 60 70 80 90
pF1KA1 ELSPSTVLYTATQHTPTSITLTVRRTKPKKRKKSPEKGRAAPKTKKIKNSPSEAQNLDEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELSPSTVLYTATQHTPTSITLTVRRTKPKKRKKSPEKGRAAPKTKKIKNSPSEAQNLDEN
150 160 170 180 190 200
100 110 120 130 140 150
pF1KA1 TTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSSKEFVGKPTILDTINKTELACN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSSKEFVGKPTILDTINKTELACN
210 220 230 240 250 260
160 170 180 190 200 210
pF1KA1 NTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKP
270 280 290 300 310 320
220 230 240 250 260 270
pF1KA1 YPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITK
330 340 350 360 370 380
280 290 300 310 320 330
pF1KA1 DAEVTIAFDYEYSNCNYKVDCACHKGNRNCPIQKRNPNATELPLLPPPPSLPTIGAETRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DAEVTIAFDYEYSNCNYKVDCACHKGNRNCPIQKRNPNATELPLLPPPPSLPTIGAETRR
390 400 410 420 430 440
340 350 360 370 380 390
pF1KA1 RKARRKELEMEQQNEASEENNDQQSQEVPEKVTVSSDHEEVDNPEEKPEEEKEEVIDDQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKARRKELEMEQQNEASEENNDQQSQEVPEKVTVSSDHEEVDNPEEKPEEEKEEVIDDQE
450 460 470 480 490 500
400 410 420 430 440 450
pF1KA1 NLAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPLEQSNSDVEITTTTSETPVGEETKTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPLEQSNSDVEITTTTSETPVGEETKTE
510 520 530 540 550 560
460 470 480 490 500 510
pF1KA1 APESEVSNSVSNVTIPSTPQSVGVNTRRSSQAGDIAAEKLVPKPPPAKPSRPRPKSRISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APESEVSNSVSNVTIPSTPQSVGVNTRRSSQAGDIAAEKLVPKPPPAKPSRPRPKSRISR
570 580 590 600 610 620
520 530 540 550 560 570
pF1KA1 YRTSSAQRLKRQKQANAQQAELSQAALEEGGSNSLVTPTEAGSLDSSGENRPLTGSDPTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRTSSAQRLKRQKQANAQQAELSQAALEEGGSNSLVTPTEAGSLDSSGENRPLTGSDPTV
630 640 650 660 670 680
580 590 600 610 620 630
pF1KA1 VSITGSHVNRAASKYPKTKKYLVTEWLNDKAEKQECPVECPLRITTDPTVLATTLNMLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSITGSHVNRAASKYPKTKKYLVTEWLNDKAEKQECPVECPLRITTDPTVLATTLNMLPG
690 700 710 720 730 740
640 650 660 670 680 690
pF1KA1 LIHSPLICTTPKHYIRFGSPFIPERRRRPLLPDGTFSSCKKRWIKQALEEGMTQTSSVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIHSPLICTTPKHYIRFGSPFIPERRRRPLLPDGTFSSCKKRWIKQALEEGMTQTSSVPQ
750 760 770 780 790 800
700 710 720 730 740 750
pF1KA1 ETRTQHLYQSNENSSSSSICKDNADLLSPLKKWKSRYLMEQNVTKLLRPLSPVTPPPPNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETRTQHLYQSNENSSSSSICKDNADLLSPLKKWKSRYLMEQNVTKLLRPLSPVTPPPPNS
810 820 830 840 850 860
760 770 780 790 800 810
pF1KA1 GSKSPQLATPGSSHPGEEECRNGYSLMFSPVTSLTTASRCNTPLQFELCHRKDLDLAKVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSKSPQLATPGSSHPGEEECRNGYSLMFSPVTSLTTASRCNTPLQFELCHRKDLDLAKVG
870 880 890 900 910 920
820 830 840 850 860 870
pF1KA1 YLDSNTNSCADRPSLLNSGHSDLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLDSNTNSCADRPSLLNSGHSDLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEF
930 940 950 960 970 980
880 890 900 910 920 930
pF1KA1 NLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGS
990 1000 1010 1020 1030 1040
940 950 960 970 980 990
pF1KA1 LSPGGERACEGVPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSPGGERACEGVPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQ
1050 1060 1070 1080 1090 1100
1000 1010 1020 1030 1040 1050
pF1KA1 GSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQEN
1110 1120 1130 1140 1150 1160
1060 1070 1080 1090 1100 1110
pF1KA1 ISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETL
1170 1180 1190 1200 1210 1220
1120 1130 1140 1150 1160 1170
pF1KA1 SSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRP
1230 1240 1250 1260 1270 1280
1180 1190 1200 1210 1220 1230
pF1KA1 GNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCP
1290 1300 1310 1320 1330 1340
1240 1250 1260 1270 1280 1290
pF1KA1 SSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQ
1350 1360 1370 1380 1390 1400
1300 1310 1320 1330
pF1KA1 ASRVSAVSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQTGLS
:::::::::::::::::::::::::::::::::::::::::
XP_016 ASRVSAVSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQTGLS
1410 1420 1430 1440
>>XP_005265358 (OMIM: 615743,615761) PREDICTED: SET doma (1461 aa)
initn: 8855 init1: 8855 opt: 8855 Z-score: 4852.7 bits: 910.4 E(85289): 0
Smith-Waterman score: 8855; 100.0% identity (100.0% similar) in 1331 aa overlap (1-1331:131-1461)
10 20 30
pF1KA1 MSRGKVIRLHRRKQDNISGGDSSATESWDE
::::::::::::::::::::::::::::::
XP_005 PNSEGETVPTWCPCGLSQDGFLLNCDKCRGMSRGKVIRLHRRKQDNISGGDSSATESWDE
110 120 130 140 150 160
40 50 60 70 80 90
pF1KA1 ELSPSTVLYTATQHTPTSITLTVRRTKPKKRKKSPEKGRAAPKTKKIKNSPSEAQNLDEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELSPSTVLYTATQHTPTSITLTVRRTKPKKRKKSPEKGRAAPKTKKIKNSPSEAQNLDEN
170 180 190 200 210 220
100 110 120 130 140 150
pF1KA1 TTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSSKEFVGKPTILDTINKTELACN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSSKEFVGKPTILDTINKTELACN
230 240 250 260 270 280
160 170 180 190 200 210
pF1KA1 NTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKP
290 300 310 320 330 340
220 230 240 250 260 270
pF1KA1 YPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITK
350 360 370 380 390 400
280 290 300 310 320 330
pF1KA1 DAEVTIAFDYEYSNCNYKVDCACHKGNRNCPIQKRNPNATELPLLPPPPSLPTIGAETRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAEVTIAFDYEYSNCNYKVDCACHKGNRNCPIQKRNPNATELPLLPPPPSLPTIGAETRR
410 420 430 440 450 460
340 350 360 370 380 390
pF1KA1 RKARRKELEMEQQNEASEENNDQQSQEVPEKVTVSSDHEEVDNPEEKPEEEKEEVIDDQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKARRKELEMEQQNEASEENNDQQSQEVPEKVTVSSDHEEVDNPEEKPEEEKEEVIDDQE
470 480 490 500 510 520
400 410 420 430 440 450
pF1KA1 NLAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPLEQSNSDVEITTTTSETPVGEETKTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPLEQSNSDVEITTTTSETPVGEETKTE
530 540 550 560 570 580
460 470 480 490 500 510
pF1KA1 APESEVSNSVSNVTIPSTPQSVGVNTRRSSQAGDIAAEKLVPKPPPAKPSRPRPKSRISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APESEVSNSVSNVTIPSTPQSVGVNTRRSSQAGDIAAEKLVPKPPPAKPSRPRPKSRISR
590 600 610 620 630 640
520 530 540 550 560 570
pF1KA1 YRTSSAQRLKRQKQANAQQAELSQAALEEGGSNSLVTPTEAGSLDSSGENRPLTGSDPTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YRTSSAQRLKRQKQANAQQAELSQAALEEGGSNSLVTPTEAGSLDSSGENRPLTGSDPTV
650 660 670 680 690 700
580 590 600 610 620 630
pF1KA1 VSITGSHVNRAASKYPKTKKYLVTEWLNDKAEKQECPVECPLRITTDPTVLATTLNMLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSITGSHVNRAASKYPKTKKYLVTEWLNDKAEKQECPVECPLRITTDPTVLATTLNMLPG
710 720 730 740 750 760
640 650 660 670 680 690
pF1KA1 LIHSPLICTTPKHYIRFGSPFIPERRRRPLLPDGTFSSCKKRWIKQALEEGMTQTSSVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIHSPLICTTPKHYIRFGSPFIPERRRRPLLPDGTFSSCKKRWIKQALEEGMTQTSSVPQ
770 780 790 800 810 820
700 710 720 730 740 750
pF1KA1 ETRTQHLYQSNENSSSSSICKDNADLLSPLKKWKSRYLMEQNVTKLLRPLSPVTPPPPNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETRTQHLYQSNENSSSSSICKDNADLLSPLKKWKSRYLMEQNVTKLLRPLSPVTPPPPNS
830 840 850 860 870 880
760 770 780 790 800 810
pF1KA1 GSKSPQLATPGSSHPGEEECRNGYSLMFSPVTSLTTASRCNTPLQFELCHRKDLDLAKVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSKSPQLATPGSSHPGEEECRNGYSLMFSPVTSLTTASRCNTPLQFELCHRKDLDLAKVG
890 900 910 920 930 940
820 830 840 850 860 870
pF1KA1 YLDSNTNSCADRPSLLNSGHSDLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YLDSNTNSCADRPSLLNSGHSDLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEF
950 960 970 980 990 1000
880 890 900 910 920 930
pF1KA1 NLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGS
1010 1020 1030 1040 1050 1060
940 950 960 970 980 990
pF1KA1 LSPGGERACEGVPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSPGGERACEGVPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQ
1070 1080 1090 1100 1110 1120
1000 1010 1020 1030 1040 1050
pF1KA1 GSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQEN
1130 1140 1150 1160 1170 1180
1060 1070 1080 1090 1100 1110
pF1KA1 ISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETL
1190 1200 1210 1220 1230 1240
1120 1130 1140 1150 1160 1170
pF1KA1 SSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRP
1250 1260 1270 1280 1290 1300
1180 1190 1200 1210 1220 1230
pF1KA1 GNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCP
1310 1320 1330 1340 1350 1360
1240 1250 1260 1270 1280 1290
pF1KA1 SSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQ
1370 1380 1390 1400 1410 1420
1300 1310 1320 1330
pF1KA1 ASRVSAVSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQTGLS
:::::::::::::::::::::::::::::::::::::::::
XP_005 ASRVSAVSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQTGLS
1430 1440 1450 1460
>>XP_016862261 (OMIM: 615743,615761) PREDICTED: SET doma (1468 aa)
initn: 8855 init1: 8855 opt: 8855 Z-score: 4852.6 bits: 910.4 E(85289): 0
Smith-Waterman score: 8855; 100.0% identity (100.0% similar) in 1331 aa overlap (1-1331:138-1468)
10 20 30
pF1KA1 MSRGKVIRLHRRKQDNISGGDSSATESWDE
::::::::::::::::::::::::::::::
XP_016 PNSEGETVPTWCPCGLSQDGFLLNCDKCRGMSRGKVIRLHRRKQDNISGGDSSATESWDE
110 120 130 140 150 160
40 50 60 70 80 90
pF1KA1 ELSPSTVLYTATQHTPTSITLTVRRTKPKKRKKSPEKGRAAPKTKKIKNSPSEAQNLDEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELSPSTVLYTATQHTPTSITLTVRRTKPKKRKKSPEKGRAAPKTKKIKNSPSEAQNLDEN
170 180 190 200 210 220
100 110 120 130 140 150
pF1KA1 TTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSSKEFVGKPTILDTINKTELACN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSSKEFVGKPTILDTINKTELACN
230 240 250 260 270 280
160 170 180 190 200 210
pF1KA1 NTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKP
290 300 310 320 330 340
220 230 240 250 260 270
pF1KA1 YPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITK
350 360 370 380 390 400
280 290 300 310 320 330
pF1KA1 DAEVTIAFDYEYSNCNYKVDCACHKGNRNCPIQKRNPNATELPLLPPPPSLPTIGAETRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DAEVTIAFDYEYSNCNYKVDCACHKGNRNCPIQKRNPNATELPLLPPPPSLPTIGAETRR
410 420 430 440 450 460
340 350 360 370 380 390
pF1KA1 RKARRKELEMEQQNEASEENNDQQSQEVPEKVTVSSDHEEVDNPEEKPEEEKEEVIDDQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKARRKELEMEQQNEASEENNDQQSQEVPEKVTVSSDHEEVDNPEEKPEEEKEEVIDDQE
470 480 490 500 510 520
400 410 420 430 440 450
pF1KA1 NLAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPLEQSNSDVEITTTTSETPVGEETKTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPLEQSNSDVEITTTTSETPVGEETKTE
530 540 550 560 570 580
460 470 480 490 500 510
pF1KA1 APESEVSNSVSNVTIPSTPQSVGVNTRRSSQAGDIAAEKLVPKPPPAKPSRPRPKSRISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APESEVSNSVSNVTIPSTPQSVGVNTRRSSQAGDIAAEKLVPKPPPAKPSRPRPKSRISR
590 600 610 620 630 640
520 530 540 550 560 570
pF1KA1 YRTSSAQRLKRQKQANAQQAELSQAALEEGGSNSLVTPTEAGSLDSSGENRPLTGSDPTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRTSSAQRLKRQKQANAQQAELSQAALEEGGSNSLVTPTEAGSLDSSGENRPLTGSDPTV
650 660 670 680 690 700
580 590 600 610 620 630
pF1KA1 VSITGSHVNRAASKYPKTKKYLVTEWLNDKAEKQECPVECPLRITTDPTVLATTLNMLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSITGSHVNRAASKYPKTKKYLVTEWLNDKAEKQECPVECPLRITTDPTVLATTLNMLPG
710 720 730 740 750 760
640 650 660 670 680 690
pF1KA1 LIHSPLICTTPKHYIRFGSPFIPERRRRPLLPDGTFSSCKKRWIKQALEEGMTQTSSVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIHSPLICTTPKHYIRFGSPFIPERRRRPLLPDGTFSSCKKRWIKQALEEGMTQTSSVPQ
770 780 790 800 810 820
700 710 720 730 740 750
pF1KA1 ETRTQHLYQSNENSSSSSICKDNADLLSPLKKWKSRYLMEQNVTKLLRPLSPVTPPPPNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETRTQHLYQSNENSSSSSICKDNADLLSPLKKWKSRYLMEQNVTKLLRPLSPVTPPPPNS
830 840 850 860 870 880
760 770 780 790 800 810
pF1KA1 GSKSPQLATPGSSHPGEEECRNGYSLMFSPVTSLTTASRCNTPLQFELCHRKDLDLAKVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSKSPQLATPGSSHPGEEECRNGYSLMFSPVTSLTTASRCNTPLQFELCHRKDLDLAKVG
890 900 910 920 930 940
820 830 840 850 860 870
pF1KA1 YLDSNTNSCADRPSLLNSGHSDLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLDSNTNSCADRPSLLNSGHSDLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEF
950 960 970 980 990 1000
880 890 900 910 920 930
pF1KA1 NLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGS
1010 1020 1030 1040 1050 1060
940 950 960 970 980 990
pF1KA1 LSPGGERACEGVPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSPGGERACEGVPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQ
1070 1080 1090 1100 1110 1120
1000 1010 1020 1030 1040 1050
pF1KA1 GSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQEN
1130 1140 1150 1160 1170 1180
1060 1070 1080 1090 1100 1110
pF1KA1 ISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETL
1190 1200 1210 1220 1230 1240
1120 1130 1140 1150 1160 1170
pF1KA1 SSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRP
1250 1260 1270 1280 1290 1300
1180 1190 1200 1210 1220 1230
pF1KA1 GNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCP
1310 1320 1330 1340 1350 1360
1240 1250 1260 1270 1280 1290
pF1KA1 SSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQ
1370 1380 1390 1400 1410 1420
1300 1310 1320 1330
pF1KA1 ASRVSAVSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQTGLS
:::::::::::::::::::::::::::::::::::::::::
XP_016 ASRVSAVSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQTGLS
1430 1440 1450 1460
>>NP_001278972 (OMIM: 615743,615761) SET domain-containi (1344 aa)
initn: 8372 init1: 8372 opt: 8394 Z-score: 4601.2 bits: 863.7 E(85289): 0
Smith-Waterman score: 8819; 99.0% identity (99.0% similar) in 1344 aa overlap (1-1331:1-1344)
10 20 30 40 50 60
pF1KA1 MSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKK
10 20 30 40 50 60
70 80 90 100
pF1KA1 RKKSPEKGRAAPKTKKIK-------------NSPSEAQNLDENTTEGWENRIRLWTDQYE
:::::::::::::::::: :::::::::::::::::::::::::::::
NP_001 RKKSPEKGRAAPKTKKIKAFREGSRKSLRMKNSPSEAQNLDENTTEGWENRIRLWTDQYE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 EAFTNQYSADVQNALEQHLHSSKEFVGKPTILDTINKTELACNNTVIGSQMQLQLGRVTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAFTNQYSADVQNALEQHLHSSKEFVGKPTILDTINKTELACNNTVIGSQMQLQLGRVTR
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 VQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCV
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA1 DARTFGNDARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DARTFGNDARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNY
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA1 KVDCACHKGNRNCPIQKRNPNATELPLLPPPPSLPTIGAETRRRKARRKELEMEQQNEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVDCACHKGNRNCPIQKRNPNATELPLLPPPPSLPTIGAETRRRKARRKELEMEQQNEAS
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 EENNDQQSQEVPEKVTVSSDHEEVDNPEEKPEEEKEEVIDDQENLAHSRRTREDRKVEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EENNDQQSQEVPEKVTVSSDHEEVDNPEEKPEEEKEEVIDDQENLAHSRRTREDRKVEAI
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA1 MHAFENLEKRKKRRDQPLEQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MHAFENLEKRKKRRDQPLEQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPS
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA1 TPQSVGVNTRRSSQAGDIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPQSVGVNTRRSSQAGDIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANA
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA1 QQAELSQAALEEGGSNSLVTPTEAGSLDSSGENRPLTGSDPTVVSITGSHVNRAASKYPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQAELSQAALEEGGSNSLVTPTEAGSLDSSGENRPLTGSDPTVVSITGSHVNRAASKYPK
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA1 TKKYLVTEWLNDKAEKQECPVECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKKYLVTEWLNDKAEKQECPVECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRF
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA1 GSPFIPERRRRPLLPDGTFSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSPFIPERRRRPLLPDGTFSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSSSS
670 680 690 700 710 720
710 720 730 740 750 760
pF1KA1 SICKDNADLLSPLKKWKSRYLMEQNVTKLLRPLSPVTPPPPNSGSKSPQLATPGSSHPGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SICKDNADLLSPLKKWKSRYLMEQNVTKLLRPLSPVTPPPPNSGSKSPQLATPGSSHPGE
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA1 EECRNGYSLMFSPVTSLTTASRCNTPLQFELCHRKDLDLAKVGYLDSNTNSCADRPSLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EECRNGYSLMFSPVTSLTTASRCNTPLQFELCHRKDLDLAKVGYLDSNTNSCADRPSLLN
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA1 SGHSDLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAMPRADG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGHSDLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAMPRADG
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA1 LYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGSLSPGGERACEGVPSAPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGSLSPGGERACEGVPSAPQ
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA1 NPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGS
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KA1 SARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREG
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KA1 GSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYS
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KA1 YQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTS
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KA1 YSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTS
1210 1220 1230 1240 1250 1260
1250 1260 1270 1280 1290 1300
pF1KA1 DSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQHYPHRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQHYPHRG
1270 1280 1290 1300 1310 1320
1310 1320 1330
pF1KA1 SGGVHQYRLQPLQGSGVKTQTGLS
::::::::::::::::::::::::
NP_001 SGGVHQYRLQPLQGSGVKTQTGLS
1330 1340
>>XP_016862270 (OMIM: 615743,615761) PREDICTED: SET doma (1344 aa)
initn: 8372 init1: 8372 opt: 8394 Z-score: 4601.2 bits: 863.7 E(85289): 0
Smith-Waterman score: 8819; 99.0% identity (99.0% similar) in 1344 aa overlap (1-1331:1-1344)
10 20 30 40 50 60
pF1KA1 MSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKK
10 20 30 40 50 60
70 80 90 100
pF1KA1 RKKSPEKGRAAPKTKKIK-------------NSPSEAQNLDENTTEGWENRIRLWTDQYE
:::::::::::::::::: :::::::::::::::::::::::::::::
XP_016 RKKSPEKGRAAPKTKKIKAFREGSRKSLRMKNSPSEAQNLDENTTEGWENRIRLWTDQYE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 EAFTNQYSADVQNALEQHLHSSKEFVGKPTILDTINKTELACNNTVIGSQMQLQLGRVTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAFTNQYSADVQNALEQHLHSSKEFVGKPTILDTINKTELACNNTVIGSQMQLQLGRVTR
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 VQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCV
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA1 DARTFGNDARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DARTFGNDARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNY
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA1 KVDCACHKGNRNCPIQKRNPNATELPLLPPPPSLPTIGAETRRRKARRKELEMEQQNEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVDCACHKGNRNCPIQKRNPNATELPLLPPPPSLPTIGAETRRRKARRKELEMEQQNEAS
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 EENNDQQSQEVPEKVTVSSDHEEVDNPEEKPEEEKEEVIDDQENLAHSRRTREDRKVEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EENNDQQSQEVPEKVTVSSDHEEVDNPEEKPEEEKEEVIDDQENLAHSRRTREDRKVEAI
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA1 MHAFENLEKRKKRRDQPLEQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MHAFENLEKRKKRRDQPLEQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPS
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA1 TPQSVGVNTRRSSQAGDIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPQSVGVNTRRSSQAGDIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANA
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA1 QQAELSQAALEEGGSNSLVTPTEAGSLDSSGENRPLTGSDPTVVSITGSHVNRAASKYPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQAELSQAALEEGGSNSLVTPTEAGSLDSSGENRPLTGSDPTVVSITGSHVNRAASKYPK
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA1 TKKYLVTEWLNDKAEKQECPVECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKKYLVTEWLNDKAEKQECPVECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRF
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA1 GSPFIPERRRRPLLPDGTFSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSPFIPERRRRPLLPDGTFSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSSSS
670 680 690 700 710 720
710 720 730 740 750 760
pF1KA1 SICKDNADLLSPLKKWKSRYLMEQNVTKLLRPLSPVTPPPPNSGSKSPQLATPGSSHPGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SICKDNADLLSPLKKWKSRYLMEQNVTKLLRPLSPVTPPPPNSGSKSPQLATPGSSHPGE
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA1 EECRNGYSLMFSPVTSLTTASRCNTPLQFELCHRKDLDLAKVGYLDSNTNSCADRPSLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EECRNGYSLMFSPVTSLTTASRCNTPLQFELCHRKDLDLAKVGYLDSNTNSCADRPSLLN
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA1 SGHSDLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAMPRADG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGHSDLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAMPRADG
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA1 LYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGSLSPGGERACEGVPSAPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGSLSPGGERACEGVPSAPQ
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA1 NPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGS
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KA1 SARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREG
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KA1 GSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYS
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KA1 YQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTS
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KA1 YSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTS
1210 1220 1230 1240 1250 1260
1250 1260 1270 1280 1290 1300
pF1KA1 DSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQHYPHRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQHYPHRG
1270 1280 1290 1300 1310 1320
1310 1320 1330
pF1KA1 SGGVHQYRLQPLQGSGVKTQTGLS
::::::::::::::::::::::::
XP_016 SGGVHQYRLQPLQGSGVKTQTGLS
1330 1340
>>XP_016862259 (OMIM: 615743,615761) PREDICTED: SET doma (1481 aa)
initn: 8372 init1: 8372 opt: 8394 Z-score: 4600.6 bits: 863.8 E(85289): 0
Smith-Waterman score: 8819; 99.0% identity (99.0% similar) in 1344 aa overlap (1-1331:138-1481)
10 20 30
pF1KA1 MSRGKVIRLHRRKQDNISGGDSSATESWDE
::::::::::::::::::::::::::::::
XP_016 PNSEGETVPTWCPCGLSQDGFLLNCDKCRGMSRGKVIRLHRRKQDNISGGDSSATESWDE
110 120 130 140 150 160
40 50 60 70
pF1KA1 ELSPSTVLYTATQHTPTSITLTVRRTKPKKRKKSPEKGRAAPKTKKIK------------
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELSPSTVLYTATQHTPTSITLTVRRTKPKKRKKSPEKGRAAPKTKKIKAFREGSRKSLRM
170 180 190 200 210 220
80 90 100 110 120 130
pF1KA1 -NSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSSKEFVGKPT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSSKEFVGKPT
230 240 250 260 270 280
140 150 160 170 180 190
pF1KA1 ILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLR
290 300 310 320 330 340
200 210 220 230 240 250
pF1KA1 QQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEVRHMIADGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEVRHMIADGM
350 360 370 380 390 400
260 270 280 290 300 310
pF1KA1 IHLCIYAVSAITKDAEVTIAFDYEYSNCNYKVDCACHKGNRNCPIQKRNPNATELPLLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHLCIYAVSAITKDAEVTIAFDYEYSNCNYKVDCACHKGNRNCPIQKRNPNATELPLLPP
410 420 430 440 450 460
320 330 340 350 360 370
pF1KA1 PPSLPTIGAETRRRKARRKELEMEQQNEASEENNDQQSQEVPEKVTVSSDHEEVDNPEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSLPTIGAETRRRKARRKELEMEQQNEASEENNDQQSQEVPEKVTVSSDHEEVDNPEEK
470 480 490 500 510 520
380 390 400 410 420 430
pF1KA1 PEEEKEEVIDDQENLAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPLEQSNSDVEITTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEEEKEEVIDDQENLAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPLEQSNSDVEITTT
530 540 550 560 570 580
440 450 460 470 480 490
pF1KA1 TSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRSSQAGDIAAEKLVPKPPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRSSQAGDIAAEKLVPKPPPA
590 600 610 620 630 640
500 510 520 530 540 550
pF1KA1 KPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAALEEGGSNSLVTPTEAGSLDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAALEEGGSNSLVTPTEAGSLDSS
650 660 670 680 690 700
560 570 580 590 600 610
pF1KA1 GENRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTEWLNDKAEKQECPVECPLRITTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GENRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTEWLNDKAEKQECPVECPLRITTD
710 720 730 740 750 760
620 630 640 650 660 670
pF1KA1 PTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFIPERRRRPLLPDGTFSSCKKRWIKQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFIPERRRRPLLPDGTFSSCKKRWIKQA
770 780 790 800 810 820
680 690 700 710 720 730
pF1KA1 LEEGMTQTSSVPQETRTQHLYQSNENSSSSSICKDNADLLSPLKKWKSRYLMEQNVTKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEEGMTQTSSVPQETRTQHLYQSNENSSSSSICKDNADLLSPLKKWKSRYLMEQNVTKLL
830 840 850 860 870 880
740 750 760 770 780 790
pF1KA1 RPLSPVTPPPPNSGSKSPQLATPGSSHPGEEECRNGYSLMFSPVTSLTTASRCNTPLQFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPLSPVTPPPPNSGSKSPQLATPGSSHPGEEECRNGYSLMFSPVTSLTTASRCNTPLQFE
890 900 910 920 930 940
800 810 820 830 840 850
pF1KA1 LCHRKDLDLAKVGYLDSNTNSCADRPSLLNSGHSDLAPHPSLGPTSETGFPSRSGDGHQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCHRKDLDLAKVGYLDSNTNSCADRPSLLNSGHSDLAPHPSLGPTSETGFPSRSGDGHQT
950 960 970 980 990 1000
860 870 880 890 900 910
pF1KA1 LVRNSDQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVRNSDQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFSSR
1010 1020 1030 1040 1050 1060
920 930 940 950 960 970
pF1KA1 YEHGLMKDLSRGSLSPGGERACEGVPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEHGLMKDLSRGSLSPGGERACEGVPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGD
1070 1080 1090 1100 1110 1120
980 990 1000 1010 1020 1030
pF1KA1 SAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDS
1130 1140 1150 1160 1170 1180
1040 1050 1060 1070 1080 1090
pF1KA1 RGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEK
1190 1200 1210 1220 1230 1240
1100 1110 1120 1130 1140 1150
pF1KA1 DSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQ
1250 1260 1270 1280 1290 1300
1160 1170 1180 1190 1200 1210
pF1KA1 SPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSG
1310 1320 1330 1340 1350 1360
1220 1230 1240 1250 1260 1270
pF1KA1 NSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRT
1370 1380 1390 1400 1410 1420
1280 1290 1300 1310 1320 1330
pF1KA1 ISLPSAGQSAVYQASRVSAVSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQTGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISLPSAGQSAVYQASRVSAVSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQTGLS
1430 1440 1450 1460 1470 1480
>>XP_016862269 (OMIM: 615743,615761) PREDICTED: SET doma (1350 aa)
initn: 5389 init1: 5275 opt: 5381 Z-score: 2954.5 bits: 559.0 E(85289): 7.9e-158
Smith-Waterman score: 8807; 98.6% identity (98.6% similar) in 1350 aa overlap (1-1331:1-1350)
10 20 30 40 50 60
pF1KA1 MSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 RKKSPEKGRAAPKTKKIKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKKSPEKGRAAPKTKKIKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 ALEQHLHSSKEFVGKPTILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALEQHLHSSKEFVGKPTILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 RSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNYKVDCACHKGNRNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNYKVDCACHKGNRNC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 PIQKRNPNATELPLLPPPPSLPTIGAETRRRKARRKELEMEQQNEASEENNDQQSQEVPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIQKRNPNATELPLLPPPPSLPTIGAETRRRKARRKELEMEQQNEASEENNDQQSQEVPE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 KVTVSSDHEEVDNPEEKPEEEKEEVIDDQENLAHSRRTREDRKVEAIMHAFENLEKRKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVTVSSDHEEVDNPEEKPEEEKEEVIDDQENLAHSRRTREDRKVEAIMHAFENLEKRKKR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 RDQPLEQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDQPLEQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 QAGDIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAALEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAGDIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAALEEG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 GSNSLVTPTEAGSLDSSGENRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTEWLNDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSNSLVTPTEAGSLDSSGENRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTEWLNDK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 AEKQECPVECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFIPERRRRPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEKQECPVECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFIPERRRRPL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 LPDGTFSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSSSSSICKDNADLLSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPDGTFSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSSSSSICKDNADLLSPL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 KKWKSRYLMEQNVTKLLRPLSPVTPPPPNSGSKSPQLATPGSSHPGEEECRNGYSLMFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKWKSRYLMEQNVTKLLRPLSPVTPPPPNSGSKSPQLATPGSSHPGEEECRNGYSLMFSP
730 740 750 760 770 780
790 800 810 820
pF1KA1 VTSLTTASRCNTPLQFE-------------------LCHRKDLDLAKVGYLDSNTNSCAD
::::::::::::::::: ::::::::::::::::::::::::
XP_016 VTSLTTASRCNTPLQFENISSPESSPAHRPESLSPELCHRKDLDLAKVGYLDSNTNSCAD
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA1 RPSLLNSGHSDLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPSLLNSGHSDLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNA
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA1 MPRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGSLSPGGERACEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGSLSPGGERACEG
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA1 VPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGA
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KA1 HGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSV
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KA1 ERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVY
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KA1 SPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSES
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KA1 SLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGP
1210 1220 1230 1240 1250 1260
1250 1260 1270 1280 1290 1300
pF1KA1 SDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQ
1270 1280 1290 1300 1310 1320
1310 1320 1330
pF1KA1 HYPHRGSGGVHQYRLQPLQGSGVKTQTGLS
::::::::::::::::::::::::::::::
XP_016 HYPHRGSGGVHQYRLQPLQGSGVKTQTGLS
1330 1340 1350
>>XP_011532234 (OMIM: 615743,615761) PREDICTED: SET doma (1350 aa)
initn: 5389 init1: 5275 opt: 5381 Z-score: 2954.5 bits: 559.0 E(85289): 7.9e-158
Smith-Waterman score: 8807; 98.6% identity (98.6% similar) in 1350 aa overlap (1-1331:1-1350)
10 20 30 40 50 60
pF1KA1 MSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 RKKSPEKGRAAPKTKKIKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKKSPEKGRAAPKTKKIKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 ALEQHLHSSKEFVGKPTILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALEQHLHSSKEFVGKPTILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 RSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNYKVDCACHKGNRNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNYKVDCACHKGNRNC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 PIQKRNPNATELPLLPPPPSLPTIGAETRRRKARRKELEMEQQNEASEENNDQQSQEVPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIQKRNPNATELPLLPPPPSLPTIGAETRRRKARRKELEMEQQNEASEENNDQQSQEVPE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 KVTVSSDHEEVDNPEEKPEEEKEEVIDDQENLAHSRRTREDRKVEAIMHAFENLEKRKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVTVSSDHEEVDNPEEKPEEEKEEVIDDQENLAHSRRTREDRKVEAIMHAFENLEKRKKR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 RDQPLEQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDQPLEQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 QAGDIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAALEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAGDIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAALEEG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 GSNSLVTPTEAGSLDSSGENRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTEWLNDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSNSLVTPTEAGSLDSSGENRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTEWLNDK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 AEKQECPVECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFIPERRRRPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEKQECPVECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFIPERRRRPL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 LPDGTFSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSSSSSICKDNADLLSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPDGTFSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSSSSSICKDNADLLSPL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 KKWKSRYLMEQNVTKLLRPLSPVTPPPPNSGSKSPQLATPGSSHPGEEECRNGYSLMFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKWKSRYLMEQNVTKLLRPLSPVTPPPPNSGSKSPQLATPGSSHPGEEECRNGYSLMFSP
730 740 750 760 770 780
790 800 810 820
pF1KA1 VTSLTTASRCNTPLQFE-------------------LCHRKDLDLAKVGYLDSNTNSCAD
::::::::::::::::: ::::::::::::::::::::::::
XP_011 VTSLTTASRCNTPLQFENISSPESSPAHRPESLSPELCHRKDLDLAKVGYLDSNTNSCAD
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA1 RPSLLNSGHSDLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPSLLNSGHSDLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNA
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA1 MPRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGSLSPGGERACEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGSLSPGGERACEG
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA1 VPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGA
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KA1 HGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSV
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KA1 ERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVY
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KA1 SPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSES
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KA1 SLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGP
1210 1220 1230 1240 1250 1260
1250 1260 1270 1280 1290 1300
pF1KA1 SDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQ
1270 1280 1290 1300 1310 1320
1310 1320 1330
pF1KA1 HYPHRGSGGVHQYRLQPLQGSGVKTQTGLS
::::::::::::::::::::::::::::::
XP_011 HYPHRGSGGVHQYRLQPLQGSGVKTQTGLS
1330 1340 1350
>>XP_011532235 (OMIM: 615743,615761) PREDICTED: SET doma (1350 aa)
initn: 5389 init1: 5275 opt: 5381 Z-score: 2954.5 bits: 559.0 E(85289): 7.9e-158
Smith-Waterman score: 8807; 98.6% identity (98.6% similar) in 1350 aa overlap (1-1331:1-1350)
10 20 30 40 50 60
pF1KA1 MSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSRGKVIRLHRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 RKKSPEKGRAAPKTKKIKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKKSPEKGRAAPKTKKIKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 ALEQHLHSSKEFVGKPTILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALEQHLHSSKEFVGKPTILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 RSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNYKVDCACHKGNRNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNYKVDCACHKGNRNC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 PIQKRNPNATELPLLPPPPSLPTIGAETRRRKARRKELEMEQQNEASEENNDQQSQEVPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIQKRNPNATELPLLPPPPSLPTIGAETRRRKARRKELEMEQQNEASEENNDQQSQEVPE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 KVTVSSDHEEVDNPEEKPEEEKEEVIDDQENLAHSRRTREDRKVEAIMHAFENLEKRKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVTVSSDHEEVDNPEEKPEEEKEEVIDDQENLAHSRRTREDRKVEAIMHAFENLEKRKKR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 RDQPLEQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDQPLEQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 QAGDIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAALEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAGDIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAALEEG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 GSNSLVTPTEAGSLDSSGENRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTEWLNDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSNSLVTPTEAGSLDSSGENRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTEWLNDK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 AEKQECPVECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFIPERRRRPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEKQECPVECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFIPERRRRPL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 LPDGTFSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSSSSSICKDNADLLSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPDGTFSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSSSSSICKDNADLLSPL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 KKWKSRYLMEQNVTKLLRPLSPVTPPPPNSGSKSPQLATPGSSHPGEEECRNGYSLMFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKWKSRYLMEQNVTKLLRPLSPVTPPPPNSGSKSPQLATPGSSHPGEEECRNGYSLMFSP
730 740 750 760 770 780
790 800 810 820
pF1KA1 VTSLTTASRCNTPLQFE-------------------LCHRKDLDLAKVGYLDSNTNSCAD
::::::::::::::::: ::::::::::::::::::::::::
XP_011 VTSLTTASRCNTPLQFENISSPESSPAHRPESLSPELCHRKDLDLAKVGYLDSNTNSCAD
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA1 RPSLLNSGHSDLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPSLLNSGHSDLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNA
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA1 MPRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGSLSPGGERACEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGSLSPGGERACEG
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA1 VPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGA
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KA1 HGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSV
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KA1 ERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVY
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KA1 SPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSES
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KA1 SLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGP
1210 1220 1230 1240 1250 1260
1250 1260 1270 1280 1290 1300
pF1KA1 SDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQ
1270 1280 1290 1300 1310 1320
1310 1320 1330
pF1KA1 HYPHRGSGGVHQYRLQPLQGSGVKTQTGLS
::::::::::::::::::::::::::::::
XP_011 HYPHRGSGGVHQYRLQPLQGSGVKTQTGLS
1330 1340 1350
1331 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 22:00:05 2016 done: Wed Nov 2 22:00:08 2016
Total Scan time: 19.500 Total Display time: 0.620
Function used was FASTA [36.3.4 Apr, 2011]