FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1760, 2210 aa 1>>>pF1KA1760 2210 - 2210 aa - 2210 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 18.2703+/-0.000567; mu= -30.1735+/- 0.036 mean_var=1205.4219+/-256.339, 0's: 0 Z-trim(124.7): 369 B-trim: 0 in 0/59 Lambda= 0.036941 statistics sampled from 46383 (46938) to 46383 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.787), E-opt: 0.2 (0.55), width: 16 Scan time: 30.820 The best scores are: opt bits E(85289) XP_005252197 (OMIM: 606249) PREDICTED: serine/thre (2224) 15087 822.1 0 XP_005252194 (OMIM: 606249) PREDICTED: serine/thre (2260) 14986 816.7 0 NP_006639 (OMIM: 606249) serine/threonine-protein (2217) 14983 816.5 0 XP_005252198 (OMIM: 606249) PREDICTED: serine/thre (2217) 14983 816.5 0 XP_016870534 (OMIM: 606249) PREDICTED: serine/thre (2259) 14969 815.8 0 XP_005252201 (OMIM: 606249) PREDICTED: serine/thre (2185) 14728 802.9 0 XP_011517234 (OMIM: 606249) PREDICTED: serine/thre (2252) 14728 802.9 0 XP_011517228 (OMIM: 606249) PREDICTED: serine/thre (2302) 14728 803.0 0 XP_011517229 (OMIM: 606249) PREDICTED: serine/thre (2301) 14711 802.1 0 XP_016870538 (OMIM: 606249) PREDICTED: serine/thre (2227) 13838 755.5 1.6e-216 XP_011517233 (OMIM: 606249) PREDICTED: serine/thre (2254) 13838 755.5 1.6e-216 XP_011517231 (OMIM: 606249) PREDICTED: serine/thre (2269) 13838 755.5 1.6e-216 XP_016870539 (OMIM: 606249) PREDICTED: serine/thre (2226) 13821 754.6 2.9e-216 XP_011517238 (OMIM: 606249) PREDICTED: serine/thre (2190) 13438 734.2 4e-210 XP_016870543 (OMIM: 606249) PREDICTED: serine/thre (2163) 13414 732.9 9.7e-210 XP_011517237 (OMIM: 606249) PREDICTED: serine/thre (2205) 13414 732.9 9.8e-210 XP_016870544 (OMIM: 606249) PREDICTED: serine/thre (2162) 13397 732.0 1.8e-209 XP_016870541 (OMIM: 606249) PREDICTED: serine/thre (2209) 13326 728.2 2.5e-208 XP_016870536 (OMIM: 606249) PREDICTED: serine/thre (2242) 13326 728.2 2.6e-208 XP_011517230 (OMIM: 606249) PREDICTED: serine/thre (2284) 13326 728.2 2.6e-208 XP_016870542 (OMIM: 606249) PREDICTED: serine/thre (2208) 13309 727.3 4.7e-208 XP_016870537 (OMIM: 606249) PREDICTED: serine/thre (2241) 13309 727.3 4.8e-208 XP_011517239 (OMIM: 606249) PREDICTED: serine/thre (2087) 13282 725.8 1.2e-207 XP_011517242 (OMIM: 606249) PREDICTED: serine/thre (2058) 13164 719.6 9.6e-206 XP_011517241 (OMIM: 606249) PREDICTED: serine/thre (2058) 13164 719.6 9.6e-206 XP_016870540 (OMIM: 606249) PREDICTED: serine/thre (2215) 10816 594.5 4.7e-168 XP_016870535 (OMIM: 606249) PREDICTED: serine/thre (2256) 10816 594.5 4.8e-168 XP_011517232 (OMIM: 606249) PREDICTED: serine/thre (2257) 10816 594.5 4.8e-168 NP_001269323 (OMIM: 606249) serine/threonine-prote (2297) 9318 514.6 5.2e-144 XP_016875323 (OMIM: 201300,605232,614492) PREDICTE (2228) 2317 141.5 1.1e-31 XP_011519309 (OMIM: 201300,605232,614492) PREDICTE (2353) 2258 138.4 9.7e-31 XP_006724656 (OMIM: 300358) PREDICTED: serine/thre (1743) 2232 136.9 2.1e-30 NP_001002838 (OMIM: 300358) serine/threonine-prote (1743) 2232 136.9 2.1e-30 XP_011529104 (OMIM: 300358) PREDICTED: serine/thre (1753) 2232 136.9 2.1e-30 XP_016885234 (OMIM: 300358) PREDICTED: serine/thre (1790) 2232 136.9 2.1e-30 XP_011519308 (OMIM: 201300,605232,614492) PREDICTE (2354) 2237 137.3 2.1e-30 XP_016885233 (OMIM: 300358) PREDICTED: serine/thre (1800) 2232 136.9 2.1e-30 XP_016885230 (OMIM: 300358) PREDICTED: serine/thre (1800) 2232 136.9 2.1e-30 NP_065973 (OMIM: 300358) serine/threonine-protein (1800) 2232 136.9 2.1e-30 XP_016885231 (OMIM: 300358) PREDICTED: serine/thre (1800) 2232 136.9 2.1e-30 XP_016885232 (OMIM: 300358) PREDICTED: serine/thre (1800) 2232 136.9 2.1e-30 XP_006719066 (OMIM: 201300,605232,614492) PREDICTE (2381) 2230 136.9 2.8e-30 NP_061852 (OMIM: 201300,605232,614492) serine/thre (2382) 2219 136.3 4.1e-30 XP_011519306 (OMIM: 201300,605232,614492) PREDICTE (2548) 2196 135.1 1e-29 XP_011519305 (OMIM: 201300,605232,614492) PREDICTE (2549) 2196 135.1 1e-29 XP_011519302 (OMIM: 201300,605232,614492) PREDICTE (2730) 2180 134.3 1.9e-29 XP_011519300 (OMIM: 201300,605232,614492) PREDICTE (2794) 2180 134.3 1.9e-29 XP_011519301 (OMIM: 201300,605232,614492) PREDICTE (2794) 2180 134.3 1.9e-29 XP_011519299 (OMIM: 201300,605232,614492) PREDICTE (2795) 2180 134.3 1.9e-29 XP_011519304 (OMIM: 201300,605232,614492) PREDICTE (2641) 2161 133.3 3.8e-29 >>XP_005252197 (OMIM: 606249) PREDICTED: serine/threonin (2224 aa) initn: 15087 init1: 15087 opt: 15087 Z-score: 4368.2 bits: 822.1 E(85289): 0 Smith-Waterman score: 15087; 100.0% identity (100.0% similar) in 2210 aa overlap (1-2210:15-2224) 10 20 30 40 pF1KA1 MEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA :::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDGDGGRRDVPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA1 EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA1 TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA1 DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA1 EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA1 WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA1 PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA1 VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA1 EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA1 WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA1 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA1 VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA1 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA1 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA1 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA1 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA1 TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KA1 SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KA1 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 1180 pF1KA1 SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK 1150 1160 1170 1180 1190 1200 1190 1200 1210 1220 1230 1240 pF1KA1 MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM 1210 1220 1230 1240 1250 1260 1250 1260 1270 1280 1290 1300 pF1KA1 LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE 1270 1280 1290 1300 1310 1320 1310 1320 1330 1340 1350 1360 pF1KA1 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP 1330 1340 1350 1360 1370 1380 1370 1380 1390 1400 1410 1420 pF1KA1 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH 1390 1400 1410 1420 1430 1440 1430 1440 1450 1460 1470 1480 pF1KA1 EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL 1450 1460 1470 1480 1490 1500 1490 1500 1510 1520 1530 1540 pF1KA1 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL 1510 1520 1530 1540 1550 1560 1550 1560 1570 1580 1590 1600 pF1KA1 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ 1570 1580 1590 1600 1610 1620 1610 1620 1630 1640 1650 1660 pF1KA1 PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF 1630 1640 1650 1660 1670 1680 1670 1680 1690 1700 1710 1720 pF1KA1 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS 1690 1700 1710 1720 1730 1740 1730 1740 1750 1760 1770 1780 pF1KA1 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVG 1750 1760 1770 1780 1790 1800 1790 1800 1810 1820 1830 1840 pF1KA1 VGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR 1810 1820 1830 1840 1850 1860 1850 1860 1870 1880 1890 1900 pF1KA1 VGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIE 1870 1880 1890 1900 1910 1920 1910 1920 1930 1940 1950 1960 pF1KA1 ALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADS 1930 1940 1950 1960 1970 1980 1970 1980 1990 2000 2010 2020 pF1KA1 SRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGW 1990 2000 2010 2020 2030 2040 2030 2040 2050 2060 2070 2080 pF1KA1 TVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPG 2050 2060 2070 2080 2090 2100 2090 2100 2110 2120 2130 2140 pF1KA1 PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEA 2110 2120 2130 2140 2150 2160 2150 2160 2170 2180 2190 2200 pF1KA1 QAGWAAPGEARAMTAPRAGVGMPRLPPAPGPLSTTVIPGAAPTLSVPTPGSCGPRAVSTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QAGWAAPGEARAMTAPRAGVGMPRLPPAPGPLSTTVIPGAAPTLSVPTPGSCGPRAVSTP 2170 2180 2190 2200 2210 2220 2210 pF1KA1 TSYT :::: XP_005 TSYT >>XP_005252194 (OMIM: 606249) PREDICTED: serine/threonin (2260 aa) initn: 14983 init1: 14983 opt: 14986 Z-score: 4339.1 bits: 816.7 E(85289): 0 Smith-Waterman score: 14986; 99.9% identity (99.9% similar) in 2200 aa overlap (1-2199:15-2214) 10 20 30 40 pF1KA1 MEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA :::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDGDGGRRDVPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA1 EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA1 TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA1 DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA1 EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA1 WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA1 PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA1 VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA1 EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA1 WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA1 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA1 VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA1 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA1 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA1 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA1 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA1 TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KA1 SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KA1 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 1180 pF1KA1 SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK 1150 1160 1170 1180 1190 1200 1190 1200 1210 1220 1230 1240 pF1KA1 MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM 1210 1220 1230 1240 1250 1260 1250 1260 1270 1280 1290 1300 pF1KA1 LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE 1270 1280 1290 1300 1310 1320 1310 1320 1330 1340 1350 1360 pF1KA1 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP 1330 1340 1350 1360 1370 1380 1370 1380 1390 1400 1410 1420 pF1KA1 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH 1390 1400 1410 1420 1430 1440 1430 1440 1450 1460 1470 1480 pF1KA1 EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL 1450 1460 1470 1480 1490 1500 1490 1500 1510 1520 1530 1540 pF1KA1 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL 1510 1520 1530 1540 1550 1560 1550 1560 1570 1580 1590 1600 pF1KA1 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ 1570 1580 1590 1600 1610 1620 1610 1620 1630 1640 1650 1660 pF1KA1 PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF 1630 1640 1650 1660 1670 1680 1670 1680 1690 1700 1710 1720 pF1KA1 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS 1690 1700 1710 1720 1730 1740 1730 1740 1750 1760 1770 1780 pF1KA1 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVG 1750 1760 1770 1780 1790 1800 1790 1800 1810 1820 1830 1840 pF1KA1 VGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR 1810 1820 1830 1840 1850 1860 1850 1860 1870 1880 1890 1900 pF1KA1 VGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIE 1870 1880 1890 1900 1910 1920 1910 1920 1930 1940 1950 1960 pF1KA1 ALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADS 1930 1940 1950 1960 1970 1980 1970 1980 1990 2000 2010 2020 pF1KA1 SRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGW 1990 2000 2010 2020 2030 2040 2030 2040 2050 2060 2070 2080 pF1KA1 TVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPG 2050 2060 2070 2080 2090 2100 2090 2100 2110 2120 2130 2140 pF1KA1 PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEA 2110 2120 2130 2140 2150 2160 2150 2160 2170 2180 2190 2200 pF1KA1 QAGWAAPGEARAMTAPRAGVGMPRLPPAPGPLSTTVIPGAAPTLSVPTP-GSCGPRAVST ::::::::::::::::::::::::::::::::::::::::::::::::: :. : XP_005 QAGWAAPGEARAMTAPRAGVGMPRLPPAPGPLSTTVIPGAAPTLSVPTPDGALGTARRNQ 2170 2180 2190 2200 2210 2220 2210 pF1KA1 PTSYT XP_005 VWFGLRVPPTACCGHSTQPRGGQRVGSKTASFAASDPVRS 2230 2240 2250 2260 >>NP_006639 (OMIM: 606249) serine/threonine-protein kina (2217 aa) initn: 14983 init1: 14983 opt: 14983 Z-score: 4338.3 bits: 816.5 E(85289): 0 Smith-Waterman score: 14983; 100.0% identity (100.0% similar) in 2195 aa overlap (1-2195:15-2209) 10 20 30 40 pF1KA1 MEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA :::::::::::::::::::::::::::::::::::::::::::::: NP_006 MDGDGGRRDVPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA1 EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA1 TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA1 DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA1 EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA1 WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA1 PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA1 VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA1 EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA1 WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA1 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA1 VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA1 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA1 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA1 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA1 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA1 TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KA1 SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KA1 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 1180 pF1KA1 SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK 1150 1160 1170 1180 1190 1200 1190 1200 1210 1220 1230 1240 pF1KA1 MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM 1210 1220 1230 1240 1250 1260 1250 1260 1270 1280 1290 1300 pF1KA1 LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE 1270 1280 1290 1300 1310 1320 1310 1320 1330 1340 1350 1360 pF1KA1 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP 1330 1340 1350 1360 1370 1380 1370 1380 1390 1400 1410 1420 pF1KA1 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH 1390 1400 1410 1420 1430 1440 1430 1440 1450 1460 1470 1480 pF1KA1 EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL 1450 1460 1470 1480 1490 1500 1490 1500 1510 1520 1530 1540 pF1KA1 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL 1510 1520 1530 1540 1550 1560 1550 1560 1570 1580 1590 1600 pF1KA1 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ 1570 1580 1590 1600 1610 1620 1610 1620 1630 1640 1650 1660 pF1KA1 PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF 1630 1640 1650 1660 1670 1680 1670 1680 1690 1700 1710 1720 pF1KA1 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS 1690 1700 1710 1720 1730 1740 1730 1740 1750 1760 1770 1780 pF1KA1 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVG 1750 1760 1770 1780 1790 1800 1790 1800 1810 1820 1830 1840 pF1KA1 VGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR 1810 1820 1830 1840 1850 1860 1850 1860 1870 1880 1890 1900 pF1KA1 VGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIE 1870 1880 1890 1900 1910 1920 1910 1920 1930 1940 1950 1960 pF1KA1 ALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 ALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADS 1930 1940 1950 1960 1970 1980 1970 1980 1990 2000 2010 2020 pF1KA1 SRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGW 1990 2000 2010 2020 2030 2040 2030 2040 2050 2060 2070 2080 pF1KA1 TVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPG 2050 2060 2070 2080 2090 2100 2090 2100 2110 2120 2130 2140 pF1KA1 PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEA 2110 2120 2130 2140 2150 2160 2150 2160 2170 2180 2190 2200 pF1KA1 QAGWAAPGEARAMTAPRAGVGMPRLPPAPGPLSTTVIPGAAPTLSVPTPGSCGPRAVSTP ::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QAGWAAPGEARAMTAPRAGVGMPRLPPAPGPLSTTVIPGAAPTLSVPTPDPESEKPD 2170 2180 2190 2200 2210 2210 pF1KA1 TSYT >>XP_005252198 (OMIM: 606249) PREDICTED: serine/threonin (2217 aa) initn: 14983 init1: 14983 opt: 14983 Z-score: 4338.3 bits: 816.5 E(85289): 0 Smith-Waterman score: 14983; 100.0% identity (100.0% similar) in 2195 aa overlap (1-2195:15-2209) 10 20 30 40 pF1KA1 MEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA :::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDGDGGRRDVPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA1 EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA1 TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA1 DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA1 EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA1 WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA1 PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA1 VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA1 EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA1 WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA1 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA1 VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA1 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA1 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA1 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA1 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA1 TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KA1 SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KA1 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 1180 pF1KA1 SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK 1150 1160 1170 1180 1190 1200 1190 1200 1210 1220 1230 1240 pF1KA1 MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM 1210 1220 1230 1240 1250 1260 1250 1260 1270 1280 1290 1300 pF1KA1 LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE 1270 1280 1290 1300 1310 1320 1310 1320 1330 1340 1350 1360 pF1KA1 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP 1330 1340 1350 1360 1370 1380 1370 1380 1390 1400 1410 1420 pF1KA1 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH 1390 1400 1410 1420 1430 1440 1430 1440 1450 1460 1470 1480 pF1KA1 EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL 1450 1460 1470 1480 1490 1500 1490 1500 1510 1520 1530 1540 pF1KA1 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL 1510 1520 1530 1540 1550 1560 1550 1560 1570 1580 1590 1600 pF1KA1 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ 1570 1580 1590 1600 1610 1620 1610 1620 1630 1640 1650 1660 pF1KA1 PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF 1630 1640 1650 1660 1670 1680 1670 1680 1690 1700 1710 1720 pF1KA1 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS 1690 1700 1710 1720 1730 1740 1730 1740 1750 1760 1770 1780 pF1KA1 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVG 1750 1760 1770 1780 1790 1800 1790 1800 1810 1820 1830 1840 pF1KA1 VGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR 1810 1820 1830 1840 1850 1860 1850 1860 1870 1880 1890 1900 pF1KA1 VGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIE 1870 1880 1890 1900 1910 1920 1910 1920 1930 1940 1950 1960 pF1KA1 ALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADS 1930 1940 1950 1960 1970 1980 1970 1980 1990 2000 2010 2020 pF1KA1 SRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGW 1990 2000 2010 2020 2030 2040 2030 2040 2050 2060 2070 2080 pF1KA1 TVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPG 2050 2060 2070 2080 2090 2100 2090 2100 2110 2120 2130 2140 pF1KA1 PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEA 2110 2120 2130 2140 2150 2160 2150 2160 2170 2180 2190 2200 pF1KA1 QAGWAAPGEARAMTAPRAGVGMPRLPPAPGPLSTTVIPGAAPTLSVPTPGSCGPRAVSTP ::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QAGWAAPGEARAMTAPRAGVGMPRLPPAPGPLSTTVIPGAAPTLSVPTPDPESEKPD 2170 2180 2190 2200 2210 2210 pF1KA1 TSYT >>XP_016870534 (OMIM: 606249) PREDICTED: serine/threonin (2259 aa) initn: 11257 init1: 11257 opt: 14969 Z-score: 4334.2 bits: 815.8 E(85289): 0 Smith-Waterman score: 14969; 99.8% identity (99.9% similar) in 2200 aa overlap (1-2199:15-2213) 10 20 30 40 pF1KA1 MEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA :::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDGDGGRRDVPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA1 EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA1 TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA1 DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA1 EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA1 WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA1 PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA1 VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA1 EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA1 WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA1 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA1 VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA1 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA1 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA1 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA1 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA1 TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KA1 SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KA1 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 1180 pF1KA1 SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK 1150 1160 1170 1180 1190 1200 1190 1200 1210 1220 1230 1240 pF1KA1 MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM 1210 1220 1230 1240 1250 1260 1250 1260 1270 1280 1290 1300 pF1KA1 LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE 1270 1280 1290 1300 1310 1320 1310 1320 1330 1340 1350 1360 pF1KA1 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP 1330 1340 1350 1360 1370 1380 1370 1380 1390 1400 1410 1420 pF1KA1 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH 1390 1400 1410 1420 1430 1440 1430 1440 1450 1460 1470 1480 pF1KA1 EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL 1450 1460 1470 1480 1490 1500 1490 1500 1510 1520 1530 1540 pF1KA1 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL 1510 1520 1530 1540 1550 1560 1550 1560 1570 1580 1590 1600 pF1KA1 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ 1570 1580 1590 1600 1610 1620 1610 1620 1630 1640 1650 1660 pF1KA1 PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF ::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::: XP_016 PLVEKSELAPTRGAVMEQGTSSSMT-ESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF 1630 1640 1650 1660 1670 1670 1680 1690 1700 1710 1720 pF1KA1 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS 1680 1690 1700 1710 1720 1730 1730 1740 1750 1760 1770 1780 pF1KA1 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVG 1740 1750 1760 1770 1780 1790 1790 1800 1810 1820 1830 1840 pF1KA1 VGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR 1800 1810 1820 1830 1840 1850 1850 1860 1870 1880 1890 1900 pF1KA1 VGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIE 1860 1870 1880 1890 1900 1910 1910 1920 1930 1940 1950 1960 pF1KA1 ALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADS 1920 1930 1940 1950 1960 1970 1970 1980 1990 2000 2010 2020 pF1KA1 SRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGW 1980 1990 2000 2010 2020 2030 2030 2040 2050 2060 2070 2080 pF1KA1 TVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPG 2040 2050 2060 2070 2080 2090 2090 2100 2110 2120 2130 2140 pF1KA1 PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEA 2100 2110 2120 2130 2140 2150 2150 2160 2170 2180 2190 2200 pF1KA1 QAGWAAPGEARAMTAPRAGVGMPRLPPAPGPLSTTVIPGAAPTLSVPTP-GSCGPRAVST ::::::::::::::::::::::::::::::::::::::::::::::::: :. : XP_016 QAGWAAPGEARAMTAPRAGVGMPRLPPAPGPLSTTVIPGAAPTLSVPTPDGALGTARRNQ 2160 2170 2180 2190 2200 2210 2210 pF1KA1 PTSYT XP_016 VWFGLRVPPTACCGHSTQPRGGQRVGSKTASFAASDPVRS 2220 2230 2240 2250 >>XP_005252201 (OMIM: 606249) PREDICTED: serine/threonin (2185 aa) initn: 14728 init1: 14728 opt: 14728 Z-score: 4264.9 bits: 802.9 E(85289): 0 Smith-Waterman score: 14728; 100.0% identity (100.0% similar) in 2158 aa overlap (1-2158:15-2172) 10 20 30 40 pF1KA1 MEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA :::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDGDGGRRDVPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA1 EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA1 TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA1 DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA1 EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA1 WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA1 PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA1 VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA1 EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA1 WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA1 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA1 VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA1 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA1 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA1 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA1 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA1 TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KA1 SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KA1 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 1180 pF1KA1 SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK 1150 1160 1170 1180 1190 1200 1190 1200 1210 1220 1230 1240 pF1KA1 MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM 1210 1220 1230 1240 1250 1260 1250 1260 1270 1280 1290 1300 pF1KA1 LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE 1270 1280 1290 1300 1310 1320 1310 1320 1330 1340 1350 1360 pF1KA1 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP 1330 1340 1350 1360 1370 1380 1370 1380 1390 1400 1410 1420 pF1KA1 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH 1390 1400 1410 1420 1430 1440 1430 1440 1450 1460 1470 1480 pF1KA1 EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL 1450 1460 1470 1480 1490 1500 1490 1500 1510 1520 1530 1540 pF1KA1 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL 1510 1520 1530 1540 1550 1560 1550 1560 1570 1580 1590 1600 pF1KA1 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ 1570 1580 1590 1600 1610 1620 1610 1620 1630 1640 1650 1660 pF1KA1 PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF 1630 1640 1650 1660 1670 1680 1670 1680 1690 1700 1710 1720 pF1KA1 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS 1690 1700 1710 1720 1730 1740 1730 1740 1750 1760 1770 1780 pF1KA1 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVG 1750 1760 1770 1780 1790 1800 1790 1800 1810 1820 1830 1840 pF1KA1 VGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR 1810 1820 1830 1840 1850 1860 1850 1860 1870 1880 1890 1900 pF1KA1 VGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIE 1870 1880 1890 1900 1910 1920 1910 1920 1930 1940 1950 1960 pF1KA1 ALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADS 1930 1940 1950 1960 1970 1980 1970 1980 1990 2000 2010 2020 pF1KA1 SRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGW 1990 2000 2010 2020 2030 2040 2030 2040 2050 2060 2070 2080 pF1KA1 TVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPG 2050 2060 2070 2080 2090 2100 2090 2100 2110 2120 2130 2140 pF1KA1 PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEA 2110 2120 2130 2140 2150 2160 2150 2160 2170 2180 2190 2200 pF1KA1 QAGWAAPGEARAMTAPRAGVGMPRLPPAPGPLSTTVIPGAAPTLSVPTPGSCGPRAVSTP :::::::::::: XP_005 QAGWAAPGEARAPQELGLSTLQIGR 2170 2180 >>XP_011517234 (OMIM: 606249) PREDICTED: serine/threonin (2252 aa) initn: 14728 init1: 14728 opt: 14728 Z-score: 4264.8 bits: 802.9 E(85289): 0 Smith-Waterman score: 14735; 98.2% identity (98.6% similar) in 2211 aa overlap (1-2208:15-2215) 10 20 30 40 pF1KA1 MEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA :::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDGDGGRRDVPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA1 EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA1 TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA1 DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA1 EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA1 WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA1 PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA1 VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA1 EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA1 WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA1 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA1 VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA1 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA1 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA1 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA1 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA1 TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KA1 SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KA1 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 1180 pF1KA1 SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK 1150 1160 1170 1180 1190 1200 1190 1200 1210 1220 1230 1240 pF1KA1 MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM 1210 1220 1230 1240 1250 1260 1250 1260 1270 1280 1290 1300 pF1KA1 LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE 1270 1280 1290 1300 1310 1320 1310 1320 1330 1340 1350 1360 pF1KA1 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP 1330 1340 1350 1360 1370 1380 1370 1380 1390 1400 1410 1420 pF1KA1 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH 1390 1400 1410 1420 1430 1440 1430 1440 1450 1460 1470 1480 pF1KA1 EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL 1450 1460 1470 1480 1490 1500 1490 1500 1510 1520 1530 1540 pF1KA1 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL 1510 1520 1530 1540 1550 1560 1550 1560 1570 1580 1590 1600 pF1KA1 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ 1570 1580 1590 1600 1610 1620 1610 1620 1630 1640 1650 1660 pF1KA1 PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF 1630 1640 1650 1660 1670 1680 1670 1680 1690 1700 1710 1720 pF1KA1 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS 1690 1700 1710 1720 1730 1740 1730 1740 1750 1760 1770 1780 pF1KA1 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVG 1750 1760 1770 1780 1790 1800 1790 1800 1810 1820 1830 1840 pF1KA1 VGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR 1810 1820 1830 1840 1850 1860 1850 1860 1870 1880 1890 1900 pF1KA1 VGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIE 1870 1880 1890 1900 1910 1920 1910 1920 1930 1940 1950 1960 pF1KA1 ALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADS 1930 1940 1950 1960 1970 1980 1970 1980 1990 2000 2010 2020 pF1KA1 SRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGW 1990 2000 2010 2020 2030 2040 2030 2040 2050 2060 2070 2080 pF1KA1 TVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPG 2050 2060 2070 2080 2090 2100 2090 2100 2110 2120 2130 2140 pF1KA1 PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEA 2110 2120 2130 2140 2150 2160 2150 2160 2170 2180 2190 2200 pF1KA1 QAGWAAPGEARAMTAPRAGVGMPRLPPAPGPLSTTVIP-GA--APTLSVPTPGSCGPRAV :::::::::::: . :: : : : :. :. :: . : . : :. XP_011 QAGWAAPGEARASV---------RLTPFPPRLEIPVVSTGSMEAPWGDDRTSSRSGD-AT 2170 2180 2190 2200 2210 2210 pF1KA1 STPTSYT :.:.. XP_011 SAPSARPSVHHGHSRSRPDPVRAHTRFLWSTRRLHTHFLYLS 2220 2230 2240 2250 >>XP_011517228 (OMIM: 606249) PREDICTED: serine/threonin (2302 aa) initn: 14728 init1: 14728 opt: 14728 Z-score: 4264.6 bits: 803.0 E(85289): 0 Smith-Waterman score: 14735; 98.2% identity (98.6% similar) in 2211 aa overlap (1-2208:15-2215) 10 20 30 40 pF1KA1 MEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA :::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDGDGGRRDVPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA1 EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA1 TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA1 DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA1 EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA1 WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA1 PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA1 VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA1 EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA1 WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA1 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA1 VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA1 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA1 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA1 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA1 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA1 TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KA1 SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KA1 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 1180 pF1KA1 SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK 1150 1160 1170 1180 1190 1200 1190 1200 1210 1220 1230 1240 pF1KA1 MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM 1210 1220 1230 1240 1250 1260 1250 1260 1270 1280 1290 1300 pF1KA1 LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE 1270 1280 1290 1300 1310 1320 1310 1320 1330 1340 1350 1360 pF1KA1 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP 1330 1340 1350 1360 1370 1380 1370 1380 1390 1400 1410 1420 pF1KA1 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH 1390 1400 1410 1420 1430 1440 1430 1440 1450 1460 1470 1480 pF1KA1 EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL 1450 1460 1470 1480 1490 1500 1490 1500 1510 1520 1530 1540 pF1KA1 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL 1510 1520 1530 1540 1550 1560 1550 1560 1570 1580 1590 1600 pF1KA1 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ 1570 1580 1590 1600 1610 1620 1610 1620 1630 1640 1650 1660 pF1KA1 PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF 1630 1640 1650 1660 1670 1680 1670 1680 1690 1700 1710 1720 pF1KA1 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS 1690 1700 1710 1720 1730 1740 1730 1740 1750 1760 1770 1780 pF1KA1 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVG 1750 1760 1770 1780 1790 1800 1790 1800 1810 1820 1830 1840 pF1KA1 VGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR 1810 1820 1830 1840 1850 1860 1850 1860 1870 1880 1890 1900 pF1KA1 VGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIE 1870 1880 1890 1900 1910 1920 1910 1920 1930 1940 1950 1960 pF1KA1 ALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADS 1930 1940 1950 1960 1970 1980 1970 1980 1990 2000 2010 2020 pF1KA1 SRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGW 1990 2000 2010 2020 2030 2040 2030 2040 2050 2060 2070 2080 pF1KA1 TVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPG 2050 2060 2070 2080 2090 2100 2090 2100 2110 2120 2130 2140 pF1KA1 PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEA 2110 2120 2130 2140 2150 2160 2150 2160 2170 2180 2190 2200 pF1KA1 QAGWAAPGEARAMTAPRAGVGMPRLPPAPGPLSTTVIP-GA--APTLSVPTPGSCGPRAV :::::::::::: . :: : : : :. :. :: . : . : :. XP_011 QAGWAAPGEARASV---------RLTPFPPRLEIPVVSTGSMEAPWGDDRTSSRSGD-AT 2170 2180 2190 2200 2210 2210 pF1KA1 STPTSYT :.:.. XP_011 SAPSARPSVHHGHSRSRPDPVRAHTRWRPRNRPEKPGVVWPPSPPHRLLWAQHSAARGTA 2220 2230 2240 2250 2260 2270 >>XP_011517229 (OMIM: 606249) PREDICTED: serine/threonin (2301 aa) initn: 11257 init1: 11257 opt: 14711 Z-score: 4259.7 bits: 802.1 E(85289): 0 Smith-Waterman score: 14718; 98.2% identity (98.6% similar) in 2211 aa overlap (1-2208:15-2214) 10 20 30 40 pF1KA1 MEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA :::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDGDGGRRDVPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA1 EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA1 TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA1 DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA1 EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA1 WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA1 PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA1 VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA1 EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA1 WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA1 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA1 VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA1 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA1 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA1 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA1 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA1 TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KA1 SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KA1 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 1180 pF1KA1 SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK 1150 1160 1170 1180 1190 1200 1190 1200 1210 1220 1230 1240 pF1KA1 MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM 1210 1220 1230 1240 1250 1260 1250 1260 1270 1280 1290 1300 pF1KA1 LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE 1270 1280 1290 1300 1310 1320 1310 1320 1330 1340 1350 1360 pF1KA1 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP 1330 1340 1350 1360 1370 1380 1370 1380 1390 1400 1410 1420 pF1KA1 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH 1390 1400 1410 1420 1430 1440 1430 1440 1450 1460 1470 1480 pF1KA1 EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL 1450 1460 1470 1480 1490 1500 1490 1500 1510 1520 1530 1540 pF1KA1 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL 1510 1520 1530 1540 1550 1560 1550 1560 1570 1580 1590 1600 pF1KA1 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ 1570 1580 1590 1600 1610 1620 1610 1620 1630 1640 1650 1660 pF1KA1 PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF ::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::: XP_011 PLVEKSELAPTRGAVMEQGTSSSMT-ESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF 1630 1640 1650 1660 1670 1670 1680 1690 1700 1710 1720 pF1KA1 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS 1680 1690 1700 1710 1720 1730 1730 1740 1750 1760 1770 1780 pF1KA1 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVG 1740 1750 1760 1770 1780 1790 1790 1800 1810 1820 1830 1840 pF1KA1 VGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR 1800 1810 1820 1830 1840 1850 1850 1860 1870 1880 1890 1900 pF1KA1 VGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIE 1860 1870 1880 1890 1900 1910 1910 1920 1930 1940 1950 1960 pF1KA1 ALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADS 1920 1930 1940 1950 1960 1970 1970 1980 1990 2000 2010 2020 pF1KA1 SRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGW 1980 1990 2000 2010 2020 2030 2030 2040 2050 2060 2070 2080 pF1KA1 TVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPG 2040 2050 2060 2070 2080 2090 2090 2100 2110 2120 2130 2140 pF1KA1 PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEA 2100 2110 2120 2130 2140 2150 2150 2160 2170 2180 2190 2200 pF1KA1 QAGWAAPGEARAMTAPRAGVGMPRLPPAPGPLSTTVIP-GA--APTLSVPTPGSCGPRAV :::::::::::: . :: : : : :. :. :: . : . : :. XP_011 QAGWAAPGEARASV---------RLTPFPPRLEIPVVSTGSMEAPWGDDRTSSRSGD-AT 2160 2170 2180 2190 2200 2210 pF1KA1 STPTSYT :.:.. XP_011 SAPSARPSVHHGHSRSRPDPVRAHTRWRPRNRPEKPGVVWPPSPPHRLLWAQHSAARGTA 2210 2220 2230 2240 2250 2260 >>XP_016870538 (OMIM: 606249) PREDICTED: serine/threonin (2227 aa) initn: 14743 init1: 13838 opt: 13838 Z-score: 4008.5 bits: 755.5 E(85289): 1.6e-216 Smith-Waterman score: 14684; 98.4% identity (98.4% similar) in 2200 aa overlap (1-2199:15-2181) 10 20 30 40 pF1KA1 MEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA :::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDGDGGRRDVPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA1 EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA1 TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA1 DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA1 EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA1 WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA1 PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA1 VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA1 EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA1 WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA1 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA1 VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA1 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA1 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA1 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA1 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA1 TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KA1 SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KA1 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 1180 pF1KA1 SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK 1150 1160 1170 1180 1190 1200 1190 1200 1210 1220 1230 1240 pF1KA1 MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM 1210 1220 1230 1240 1250 1260 1250 1260 1270 1280 1290 1300 pF1KA1 LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE 1270 1280 1290 1300 1310 1320 1310 1320 1330 1340 1350 1360 pF1KA1 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP 1330 1340 1350 1360 1370 1380 1370 1380 1390 1400 1410 1420 pF1KA1 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH 1390 1400 1410 1420 1430 1440 1430 1440 1450 1460 1470 1480 pF1KA1 EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL 1450 1460 1470 1480 1490 1500 1490 1500 1510 1520 1530 1540 pF1KA1 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL 1510 1520 1530 1540 1550 1560 1550 1560 1570 1580 1590 1600 pF1KA1 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ 1570 1580 1590 1600 1610 1620 1610 1620 1630 1640 1650 1660 pF1KA1 PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF 1630 1640 1650 1660 1670 1680 1670 1680 1690 1700 1710 1720 pF1KA1 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS 1690 1700 1710 1720 1730 1740 1730 1740 1750 1760 1770 1780 pF1KA1 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVG 1750 1760 1770 1780 1790 1800 1790 1800 1810 1820 1830 1840 pF1KA1 VGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR 1810 1820 1830 1840 1850 1860 1850 1860 1870 1880 1890 1900 pF1KA1 VGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIE 1870 1880 1890 1900 1910 1920 1910 1920 1930 1940 1950 1960 pF1KA1 ALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADS 1930 1940 1950 1960 1970 1980 1970 1980 1990 2000 2010 2020 pF1KA1 SRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGW ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQG- 1990 2000 2010 2020 2030 2030 2040 2050 2060 2070 2080 pF1KA1 TVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPG :::::::::::::::::::::::::::: XP_016 --------------------------------SALKRLCLGKEHSSRSSTSSLAPGPEPG 2040 2050 2060 2090 2100 2110 2120 2130 2140 pF1KA1 PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEA 2070 2080 2090 2100 2110 2120 2150 2160 2170 2180 2190 2200 pF1KA1 QAGWAAPGEARAMTAPRAGVGMPRLPPAPGPLSTTVIPGAAPTLSVPTP-GSCGPRAVST ::::::::::::::::::::::::::::::::::::::::::::::::: :. : XP_016 QAGWAAPGEARAMTAPRAGVGMPRLPPAPGPLSTTVIPGAAPTLSVPTPDGALGTARRNQ 2130 2140 2150 2160 2170 2180 2210 pF1KA1 PTSYT XP_016 VWFGLRVPPTACCGHSTQPRGGQRVGSKTASFAASDPVRS 2190 2200 2210 2220 2210 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 01:46:47 2016 done: Fri Nov 4 01:46:51 2016 Total Scan time: 30.820 Total Display time: 1.730 Function used was FASTA [36.3.4 Apr, 2011]