FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1779, 1210 aa 1>>>pF1KA1779 1210 - 1210 aa - 1210 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.5859+/-0.000504; mu= -22.1240+/- 0.031 mean_var=532.4049+/-113.842, 0's: 0 Z-trim(120.8): 113 B-trim: 1647 in 1/57 Lambda= 0.055584 statistics sampled from 36421 (36541) to 36421 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.736), E-opt: 0.2 (0.428), width: 16 Scan time: 13.710 The best scores are: opt bits E(85289) NP_001276791 (OMIM: 603427,616882) period circadia (1210) 8130 668.0 1e-190 XP_016858212 (OMIM: 603427,616882) PREDICTED: peri (1209) 8113 666.6 2.7e-190 XP_011540687 (OMIM: 603427,616882) PREDICTED: peri (1209) 8111 666.4 3e-190 XP_016858213 (OMIM: 603427,616882) PREDICTED: peri (1208) 8094 665.1 7.7e-190 XP_016858214 (OMIM: 603427,616882) PREDICTED: peri (1203) 8059 662.3 5.4e-189 XP_016858215 (OMIM: 603427,616882) PREDICTED: peri (1202) 8042 660.9 1.4e-188 XP_011540692 (OMIM: 603427,616882) PREDICTED: peri (1202) 8040 660.7 1.5e-188 NP_058515 (OMIM: 603427,616882) period circadian p (1201) 8023 659.4 4e-188 XP_005263581 (OMIM: 603427,616882) PREDICTED: peri (1203) 7951 653.6 2.2e-186 XP_016858216 (OMIM: 603427,616882) PREDICTED: peri (1154) 7745 637.1 2e-181 XP_016858217 (OMIM: 603427,616882) PREDICTED: peri (1094) 7277 599.5 3.8e-170 XP_016858219 (OMIM: 603427,616882) PREDICTED: peri (1093) 7258 598.0 1.1e-169 XP_016858218 (OMIM: 603427,616882) PREDICTED: peri (1089) 7256 597.8 1.2e-169 XP_016858220 (OMIM: 603427,616882) PREDICTED: peri (1086) 7187 592.3 5.6e-168 XP_016858221 (OMIM: 603427,616882) PREDICTED: peri (1080) 7027 579.5 4e-164 XP_016858222 (OMIM: 603427,616882) PREDICTED: peri (1035) 6993 576.7 2.6e-163 XP_016858223 (OMIM: 603427,616882) PREDICTED: peri (1035) 6993 576.7 2.6e-163 XP_016858224 (OMIM: 603427,616882) PREDICTED: peri (1034) 6974 575.2 7.4e-163 NP_001276790 (OMIM: 603427,616882) period circadia (1191) 6972 575.1 9.3e-163 XP_016858225 (OMIM: 603427,616882) PREDICTED: peri (1028) 6922 571.0 1.3e-161 NP_001276792 (OMIM: 603427,616882) period circadia (1184) 6900 569.3 5.1e-161 NP_001276793 (OMIM: 603427,616882) period circadia ( 890) 5950 493.1 3.4e-138 XP_016858226 (OMIM: 603427,616882) PREDICTED: peri ( 746) 4992 416.2 4e-115 XP_016858227 (OMIM: 603427,616882) PREDICTED: peri ( 745) 4973 414.7 1.1e-114 XP_005256746 (OMIM: 602260) PREDICTED: period circ (1290) 1765 157.6 4.9e-37 NP_002607 (OMIM: 602260) period circadian protein (1290) 1765 157.6 4.9e-37 XP_005256747 (OMIM: 602260) PREDICTED: period circ (1230) 1623 146.2 1.3e-33 XP_005246168 (OMIM: 603426,604348) PREDICTED: peri (1255) 1543 139.8 1.1e-31 NP_073728 (OMIM: 603426,604348) period circadian p (1255) 1543 139.8 1.1e-31 XP_006712887 (OMIM: 603426,604348) PREDICTED: peri (1255) 1543 139.8 1.1e-31 >>NP_001276791 (OMIM: 603427,616882) period circadian pr (1210 aa) initn: 8130 init1: 8130 opt: 8130 Z-score: 3544.8 bits: 668.0 E(85289): 1e-190 Smith-Waterman score: 8130; 99.8% identity (99.9% similar) in 1210 aa overlap (1-1210:1-1210) 10 20 30 40 50 60 pF1KA1 MPRGEAPGPGRRGAKDEALGEESGERWSPEFHLQRKLADSSHSEQQDRNRVSEELIMVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPRGEAPGPGRRGAKDEALGEESGERWSPEFHLQRKLADSSHSEQQDRNRVSEELIMVVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 EMKKYFPSERRNKPSTLDALNYALRCVHSVQANSEFFQILSQNGAPQADVSMYSLEELAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EMKKYFPSERRNKPSTLDALNYALRCVHSVQANSEFFQILSQNGAPQADVSMYSLEELAT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 IASEHTSKNTDTFVAVFSFLSGRLVHISEQAALILNRKKDVLASSHFVDLLAPQDMRVFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IASEHTSKNTDTFVAVFSFLSGRLVHISEQAALILNRKKDVLASSHFVDLLAPQDMRVFY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 AHTARAQLPFWNNWTQRAAARYECAPVKPFFCRIRGGEDRKQEKCHSPFRIIPYLIHVHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AHTARAQLPFWNNWTQRAAARYECAPVKPFFCRIRGGEDRKQEKCHSPFRIIPYLIHVHH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 PAQPELESEPCCLTVVEKIHSGYEAPRIPVNKRIFTTTHTPGCVFLEVDEKAVPLLGYLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAQPELESEPCCLTVVEKIHSGYEAPRIPVNKRIFTTTHTPGCVFLEVDEKAVPLLGYLP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 QDLIGTSILSYLHPEDRSLMVAIHQKVLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QDLIGTSILSYLHPEDRSLMVAIHQKVLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 VNPWSRKISFIIGRHKVRTSPLNEDVFATKIKKMNDNDKDITELQEQIYKLLLQPVHVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNPWSRKISFIIGRHKVRTSPLNEDVFATKIKKMNDNDKDITELQEQIYKLLLQPVHVSV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 SSGYGSLGSSGSQEQLVSIASSSEASGHRVEETKAEQMTLQQVYASVNKIKNLGQQLYIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSGYGSLGSSGSQEQLVSIASSSEASGHRVEETKAEQMTLQQVYASVNKIKNLGQQLYIE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SMTKSSFKPVTGTRTEPNGGGESANGGGECKTFTSFHQTLKNNSVYTEPCEDLRNDEHSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SMTKSSFKPVTGTRTEPNGGGESANGGGECKTFTSFHQTLKNNSVYTEPCEDLRNDEHSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SYQQINCIDSVIRYLKSYNIPALKRKCISCTNTTSSSSEEDKQNHKADDVQALQAGLQIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SYQQINCIDSVIRYLKSYNIPALKRKCISCTNTTSSSSEEDKQNHKADDVQALQAGLQIP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 AIPKSEMPTNGRSIDTGGGAPQILSTAMLSLGSGISQCGYSSTIVHVPPPETARDATLFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AIPKSEMPTNGRSIDTGGGAPQILSTAMLSLGSGISQCGYSSTIVHVPPPETARDATLFC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 EPWTLNMQPAPLTSEEFKHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPWTLNMQPAPLTSEEFKHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 SKAKYSYFQGDSTSKQTRSAGCRKGKHKRKKLPEPPDSSSSNTGSGPRRGAHQNAQPCCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKAKYSYFQGDSTSKQTRSAGCRKGKHKRKKLPEPPDSSSSNTGSGPRRGAHQNAQPCCP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 SAASSPHTSSPTFPPAAMVPSQAPYLVPAFPLPAATSPGREYAAPGTAPEGLHGPPLSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: NP_001 SAASSPHTSSPTFPPAAMVPSQAPYLVPAFPLPAATSPGREYAAPGTAPEGLHGLPLSEG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 LQPYPAFPFPYLDTFMTVFLPDPPVCPLLSPSFLPCPFLGATASSAISPSMSSAMSPTLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQPYPAFPFPYLDTFMTVFLPDPPVCPLLSPSFLPCPFLGATASSAISPSMSSAMSPTLD 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 PPPSVTSQRREEEKWEAQSEGHPFITSRSSSPLQLNLLQEEMPRPSESPDRMRRNTCPQT ::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::: NP_001 PPPSVTSQRREEEKWEAQSEGHPFITSRSSSPLQLNLLQEEMPRPSESPDQMRRNTCPQT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 EYQCVTGNNGSESSPATTGALSTGSPPRENPSHPTASALSTGSPPMKNPSHPTASALSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EYQCVTGNNGSESSPATTGALSTGSPPRENPSHPTASALSTGSPPMKNPSHPTASALSTG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 SPPMKNPSHPTASTLSMGLPPSRTPSHPTATVLSTGSPPSESPSRTGSAASGSSDSSIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPPMKNPSHPTASTLSMGLPPSRTPSHPTATVLSTGSPPSESPSRTGSAASGSSDSSIYL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 TSSVYSSKISQNGQQSQDVQKKETFPNVAEEPIWRMIRQTPERILMTYQVPERVKEVVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSSVYSSKISQNGQQSQDVQKKETFPNVAEEPIWRMIRQTPERILMTYQVPERVKEVVLK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 EDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTCENEDSADGAATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTCENEDSADGAATS 1150 1160 1170 1180 1190 1200 1210 pF1KA1 CGQVLVEDSC :::::::::: NP_001 CGQVLVEDSC 1210 >>XP_016858212 (OMIM: 603427,616882) PREDICTED: period c (1209 aa) initn: 6823 init1: 6823 opt: 8113 Z-score: 3537.4 bits: 666.6 E(85289): 2.7e-190 Smith-Waterman score: 8113; 99.8% identity (99.8% similar) in 1210 aa overlap (1-1210:1-1209) 10 20 30 40 50 60 pF1KA1 MPRGEAPGPGRRGAKDEALGEESGERWSPEFHLQRKLADSSHSEQQDRNRVSEELIMVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPRGEAPGPGRRGAKDEALGEESGERWSPEFHLQRKLADSSHSEQQDRNRVSEELIMVVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 EMKKYFPSERRNKPSTLDALNYALRCVHSVQANSEFFQILSQNGAPQADVSMYSLEELAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMKKYFPSERRNKPSTLDALNYALRCVHSVQANSEFFQILSQNGAPQADVSMYSLEELAT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 IASEHTSKNTDTFVAVFSFLSGRLVHISEQAALILNRKKDVLASSHFVDLLAPQDMRVFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IASEHTSKNTDTFVAVFSFLSGRLVHISEQAALILNRKKDVLASSHFVDLLAPQDMRVFY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 AHTARAQLPFWNNWTQRAAARYECAPVKPFFCRIRGGEDRKQEKCHSPFRIIPYLIHVHH ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_016 AHTARAQLPFWNNWTQRAA-RYECAPVKPFFCRIRGGEDRKQEKCHSPFRIIPYLIHVHH 190 200 210 220 230 250 260 270 280 290 300 pF1KA1 PAQPELESEPCCLTVVEKIHSGYEAPRIPVNKRIFTTTHTPGCVFLEVDEKAVPLLGYLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAQPELESEPCCLTVVEKIHSGYEAPRIPVNKRIFTTTHTPGCVFLEVDEKAVPLLGYLP 240 250 260 270 280 290 310 320 330 340 350 360 pF1KA1 QDLIGTSILSYLHPEDRSLMVAIHQKVLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QDLIGTSILSYLHPEDRSLMVAIHQKVLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSF 300 310 320 330 340 350 370 380 390 400 410 420 pF1KA1 VNPWSRKISFIIGRHKVRTSPLNEDVFATKIKKMNDNDKDITELQEQIYKLLLQPVHVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNPWSRKISFIIGRHKVRTSPLNEDVFATKIKKMNDNDKDITELQEQIYKLLLQPVHVSV 360 370 380 390 400 410 430 440 450 460 470 480 pF1KA1 SSGYGSLGSSGSQEQLVSIASSSEASGHRVEETKAEQMTLQQVYASVNKIKNLGQQLYIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSGYGSLGSSGSQEQLVSIASSSEASGHRVEETKAEQMTLQQVYASVNKIKNLGQQLYIE 420 430 440 450 460 470 490 500 510 520 530 540 pF1KA1 SMTKSSFKPVTGTRTEPNGGGESANGGGECKTFTSFHQTLKNNSVYTEPCEDLRNDEHSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SMTKSSFKPVTGTRTEPNGGGESANGGGECKTFTSFHQTLKNNSVYTEPCEDLRNDEHSP 480 490 500 510 520 530 550 560 570 580 590 600 pF1KA1 SYQQINCIDSVIRYLKSYNIPALKRKCISCTNTTSSSSEEDKQNHKADDVQALQAGLQIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SYQQINCIDSVIRYLKSYNIPALKRKCISCTNTTSSSSEEDKQNHKADDVQALQAGLQIP 540 550 560 570 580 590 610 620 630 640 650 660 pF1KA1 AIPKSEMPTNGRSIDTGGGAPQILSTAMLSLGSGISQCGYSSTIVHVPPPETARDATLFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIPKSEMPTNGRSIDTGGGAPQILSTAMLSLGSGISQCGYSSTIVHVPPPETARDATLFC 600 610 620 630 640 650 670 680 690 700 710 720 pF1KA1 EPWTLNMQPAPLTSEEFKHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPWTLNMQPAPLTSEEFKHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESR 660 670 680 690 700 710 730 740 750 760 770 780 pF1KA1 SKAKYSYFQGDSTSKQTRSAGCRKGKHKRKKLPEPPDSSSSNTGSGPRRGAHQNAQPCCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKAKYSYFQGDSTSKQTRSAGCRKGKHKRKKLPEPPDSSSSNTGSGPRRGAHQNAQPCCP 720 730 740 750 760 770 790 800 810 820 830 840 pF1KA1 SAASSPHTSSPTFPPAAMVPSQAPYLVPAFPLPAATSPGREYAAPGTAPEGLHGPPLSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_016 SAASSPHTSSPTFPPAAMVPSQAPYLVPAFPLPAATSPGREYAAPGTAPEGLHGLPLSEG 780 790 800 810 820 830 850 860 870 880 890 900 pF1KA1 LQPYPAFPFPYLDTFMTVFLPDPPVCPLLSPSFLPCPFLGATASSAISPSMSSAMSPTLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQPYPAFPFPYLDTFMTVFLPDPPVCPLLSPSFLPCPFLGATASSAISPSMSSAMSPTLD 840 850 860 870 880 890 910 920 930 940 950 960 pF1KA1 PPPSVTSQRREEEKWEAQSEGHPFITSRSSSPLQLNLLQEEMPRPSESPDRMRRNTCPQT ::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::: XP_016 PPPSVTSQRREEEKWEAQSEGHPFITSRSSSPLQLNLLQEEMPRPSESPDQMRRNTCPQT 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KA1 EYQCVTGNNGSESSPATTGALSTGSPPRENPSHPTASALSTGSPPMKNPSHPTASALSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EYQCVTGNNGSESSPATTGALSTGSPPRENPSHPTASALSTGSPPMKNPSHPTASALSTG 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KA1 SPPMKNPSHPTASTLSMGLPPSRTPSHPTATVLSTGSPPSESPSRTGSAASGSSDSSIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPPMKNPSHPTASTLSMGLPPSRTPSHPTATVLSTGSPPSESPSRTGSAASGSSDSSIYL 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KA1 TSSVYSSKISQNGQQSQDVQKKETFPNVAEEPIWRMIRQTPERILMTYQVPERVKEVVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSSVYSSKISQNGQQSQDVQKKETFPNVAEEPIWRMIRQTPERILMTYQVPERVKEVVLK 1080 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 pF1KA1 EDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTCENEDSADGAATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTCENEDSADGAATS 1140 1150 1160 1170 1180 1190 1210 pF1KA1 CGQVLVEDSC :::::::::: XP_016 CGQVLVEDSC 1200 >>XP_011540687 (OMIM: 603427,616882) PREDICTED: period c (1209 aa) initn: 6702 init1: 6498 opt: 8111 Z-score: 3536.6 bits: 666.4 E(85289): 3e-190 Smith-Waterman score: 8111; 99.8% identity (99.8% similar) in 1210 aa overlap (1-1210:1-1209) 10 20 30 40 50 60 pF1KA1 MPRGEAPGPGRRGAKDEALGEESGERWSPEFHLQRKLADSSHSEQQDRNRVSEELIMVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPRGEAPGPGRRGAKDEALGEESGERWSPEFHLQRKLADSSHSEQQDRNRVSEELIMVVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 EMKKYFPSERRNKPSTLDALNYALRCVHSVQANSEFFQILSQNGAPQADVSMYSLEELAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMKKYFPSERRNKPSTLDALNYALRCVHSVQANSEFFQILSQNGAPQADVSMYSLEELAT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 IASEHTSKNTDTFVAVFSFLSGRLVHISEQAALILNRKKDVLASSHFVDLLAPQDMRVFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IASEHTSKNTDTFVAVFSFLSGRLVHISEQAALILNRKKDVLASSHFVDLLAPQDMRVFY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 AHTARAQLPFWNNWTQRAAARYECAPVKPFFCRIRGGEDRKQEKCHSPFRIIPYLIHVHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AHTARAQLPFWNNWTQRAAARYECAPVKPFFCRIRGGEDRKQEKCHSPFRIIPYLIHVHH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 PAQPELESEPCCLTVVEKIHSGYEAPRIPVNKRIFTTTHTPGCVFLEVDEKAVPLLGYLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAQPELESEPCCLTVVEKIHSGYEAPRIPVNKRIFTTTHTPGCVFLEVDEKAVPLLGYLP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 QDLIGTSILSYLHPEDRSLMVAIHQKVLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QDLIGTSILSYLHPEDRSLMVAIHQKVLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 VNPWSRKISFIIGRHKVRTSPLNEDVFATKIKKMNDNDKDITELQEQIYKLLLQPVHVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNPWSRKISFIIGRHKVRTSPLNEDVFATKIKKMNDNDKDITELQEQIYKLLLQPVHVSV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 SSGYGSLGSSGSQEQLVSIASSSEASGHRVEETKAEQMTLQQVYASVNKIKNLGQQLYIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSGYGSLGSSGSQEQLVSIASSSEASGHRVEETKAEQMTLQQVYASVNKIKNLGQQLYIE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SMTKSSFKPVTGTRTEPNGGGESANGGGECKTFTSFHQTLKNNSVYTEPCEDLRNDEHSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SMTKSSFKPVTGTRTEPNGGGESANGGGECKTFTSFHQTLKNNSVYTEPCEDLRNDEHSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SYQQINCIDSVIRYLKSYNIPALKRKCISCTNTTSSSSEEDKQNHKADDVQALQAGLQIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SYQQINCIDSVIRYLKSYNIPALKRKCISCTNTTSSSSEEDKQNHKADDVQALQAGLQIP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 AIPKSEMPTNGRSIDTGGGAPQILSTAMLSLGSGISQCGYSSTIVHVPPPETARDATLFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AIPKSEMPTNGRSIDTGGGAPQILSTAMLSLGSGISQCGYSSTIVHVPPPETARDATLFC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 EPWTLNMQPAPLTSEEFKHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPWTLNMQPAPLTSEEFKHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 SKAKYSYFQGDSTSKQTRSAGCRKGKHKRKKLPEPPDSSSSNTGSGPRRGAHQNAQPCCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKAKYSYFQGDSTSKQTRSAGCRKGKHKRKKLPEPPDSSSSNTGSGPRRGAHQNAQPCCP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 SAASSPHTSSPTFPPAAMVPSQAPYLVPAFPLPAATSPGREYAAPGTAPEGLHGPPLSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_011 SAASSPHTSSPTFPPAAMVPSQAPYLVPAFPLPAATSPGREYAAPGTAPEGLHGLPLSEG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 LQPYPAFPFPYLDTFMTVFLPDPPVCPLLSPSFLPCPFLGATASSAISPSMSSAMSPTLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQPYPAFPFPYLDTFMTVFLPDPPVCPLLSPSFLPCPFLGATASSAISPSMSSAMSPTLD 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 PPPSVTSQRREEEKWEAQSEGHPFITSRSSSPLQLNLLQEEMPRPSESPDRMRRNTCPQT ::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::: XP_011 PPPSVTSQRREEEKWEAQSEGHPFITSRSSSPLQLNLLQEEMPRPSESPDQMRRNTCPQT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 EYQCVTGNNGSESSPATTGALSTGSPPRENPSHPTASALSTGSPPMKNPSHPTASALSTG :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EY-CVTGNNGSESSPATTGALSTGSPPRENPSHPTASALSTGSPPMKNPSHPTASALSTG 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KA1 SPPMKNPSHPTASTLSMGLPPSRTPSHPTATVLSTGSPPSESPSRTGSAASGSSDSSIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPPMKNPSHPTASTLSMGLPPSRTPSHPTATVLSTGSPPSESPSRTGSAASGSSDSSIYL 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KA1 TSSVYSSKISQNGQQSQDVQKKETFPNVAEEPIWRMIRQTPERILMTYQVPERVKEVVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSSVYSSKISQNGQQSQDVQKKETFPNVAEEPIWRMIRQTPERILMTYQVPERVKEVVLK 1080 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 pF1KA1 EDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTCENEDSADGAATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTCENEDSADGAATS 1140 1150 1160 1170 1180 1190 1210 pF1KA1 CGQVLVEDSC :::::::::: XP_011 CGQVLVEDSC 1200 >>XP_016858213 (OMIM: 603427,616882) PREDICTED: period c (1208 aa) initn: 5395 init1: 5191 opt: 8094 Z-score: 3529.2 bits: 665.1 E(85289): 7.7e-190 Smith-Waterman score: 8094; 99.7% identity (99.8% similar) in 1210 aa overlap (1-1210:1-1208) 10 20 30 40 50 60 pF1KA1 MPRGEAPGPGRRGAKDEALGEESGERWSPEFHLQRKLADSSHSEQQDRNRVSEELIMVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPRGEAPGPGRRGAKDEALGEESGERWSPEFHLQRKLADSSHSEQQDRNRVSEELIMVVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 EMKKYFPSERRNKPSTLDALNYALRCVHSVQANSEFFQILSQNGAPQADVSMYSLEELAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMKKYFPSERRNKPSTLDALNYALRCVHSVQANSEFFQILSQNGAPQADVSMYSLEELAT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 IASEHTSKNTDTFVAVFSFLSGRLVHISEQAALILNRKKDVLASSHFVDLLAPQDMRVFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IASEHTSKNTDTFVAVFSFLSGRLVHISEQAALILNRKKDVLASSHFVDLLAPQDMRVFY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 AHTARAQLPFWNNWTQRAAARYECAPVKPFFCRIRGGEDRKQEKCHSPFRIIPYLIHVHH ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_016 AHTARAQLPFWNNWTQRAA-RYECAPVKPFFCRIRGGEDRKQEKCHSPFRIIPYLIHVHH 190 200 210 220 230 250 260 270 280 290 300 pF1KA1 PAQPELESEPCCLTVVEKIHSGYEAPRIPVNKRIFTTTHTPGCVFLEVDEKAVPLLGYLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAQPELESEPCCLTVVEKIHSGYEAPRIPVNKRIFTTTHTPGCVFLEVDEKAVPLLGYLP 240 250 260 270 280 290 310 320 330 340 350 360 pF1KA1 QDLIGTSILSYLHPEDRSLMVAIHQKVLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QDLIGTSILSYLHPEDRSLMVAIHQKVLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSF 300 310 320 330 340 350 370 380 390 400 410 420 pF1KA1 VNPWSRKISFIIGRHKVRTSPLNEDVFATKIKKMNDNDKDITELQEQIYKLLLQPVHVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNPWSRKISFIIGRHKVRTSPLNEDVFATKIKKMNDNDKDITELQEQIYKLLLQPVHVSV 360 370 380 390 400 410 430 440 450 460 470 480 pF1KA1 SSGYGSLGSSGSQEQLVSIASSSEASGHRVEETKAEQMTLQQVYASVNKIKNLGQQLYIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSGYGSLGSSGSQEQLVSIASSSEASGHRVEETKAEQMTLQQVYASVNKIKNLGQQLYIE 420 430 440 450 460 470 490 500 510 520 530 540 pF1KA1 SMTKSSFKPVTGTRTEPNGGGESANGGGECKTFTSFHQTLKNNSVYTEPCEDLRNDEHSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SMTKSSFKPVTGTRTEPNGGGESANGGGECKTFTSFHQTLKNNSVYTEPCEDLRNDEHSP 480 490 500 510 520 530 550 560 570 580 590 600 pF1KA1 SYQQINCIDSVIRYLKSYNIPALKRKCISCTNTTSSSSEEDKQNHKADDVQALQAGLQIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SYQQINCIDSVIRYLKSYNIPALKRKCISCTNTTSSSSEEDKQNHKADDVQALQAGLQIP 540 550 560 570 580 590 610 620 630 640 650 660 pF1KA1 AIPKSEMPTNGRSIDTGGGAPQILSTAMLSLGSGISQCGYSSTIVHVPPPETARDATLFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIPKSEMPTNGRSIDTGGGAPQILSTAMLSLGSGISQCGYSSTIVHVPPPETARDATLFC 600 610 620 630 640 650 670 680 690 700 710 720 pF1KA1 EPWTLNMQPAPLTSEEFKHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPWTLNMQPAPLTSEEFKHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESR 660 670 680 690 700 710 730 740 750 760 770 780 pF1KA1 SKAKYSYFQGDSTSKQTRSAGCRKGKHKRKKLPEPPDSSSSNTGSGPRRGAHQNAQPCCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKAKYSYFQGDSTSKQTRSAGCRKGKHKRKKLPEPPDSSSSNTGSGPRRGAHQNAQPCCP 720 730 740 750 760 770 790 800 810 820 830 840 pF1KA1 SAASSPHTSSPTFPPAAMVPSQAPYLVPAFPLPAATSPGREYAAPGTAPEGLHGPPLSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_016 SAASSPHTSSPTFPPAAMVPSQAPYLVPAFPLPAATSPGREYAAPGTAPEGLHGLPLSEG 780 790 800 810 820 830 850 860 870 880 890 900 pF1KA1 LQPYPAFPFPYLDTFMTVFLPDPPVCPLLSPSFLPCPFLGATASSAISPSMSSAMSPTLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQPYPAFPFPYLDTFMTVFLPDPPVCPLLSPSFLPCPFLGATASSAISPSMSSAMSPTLD 840 850 860 870 880 890 910 920 930 940 950 960 pF1KA1 PPPSVTSQRREEEKWEAQSEGHPFITSRSSSPLQLNLLQEEMPRPSESPDRMRRNTCPQT ::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::: XP_016 PPPSVTSQRREEEKWEAQSEGHPFITSRSSSPLQLNLLQEEMPRPSESPDQMRRNTCPQT 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KA1 EYQCVTGNNGSESSPATTGALSTGSPPRENPSHPTASALSTGSPPMKNPSHPTASALSTG :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EY-CVTGNNGSESSPATTGALSTGSPPRENPSHPTASALSTGSPPMKNPSHPTASALSTG 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KA1 SPPMKNPSHPTASTLSMGLPPSRTPSHPTATVLSTGSPPSESPSRTGSAASGSSDSSIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPPMKNPSHPTASTLSMGLPPSRTPSHPTATVLSTGSPPSESPSRTGSAASGSSDSSIYL 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KA1 TSSVYSSKISQNGQQSQDVQKKETFPNVAEEPIWRMIRQTPERILMTYQVPERVKEVVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSSVYSSKISQNGQQSQDVQKKETFPNVAEEPIWRMIRQTPERILMTYQVPERVKEVVLK 1080 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 pF1KA1 EDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTCENEDSADGAATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTCENEDSADGAATS 1140 1150 1160 1170 1180 1190 1210 pF1KA1 CGQVLVEDSC :::::::::: XP_016 CGQVLVEDSC 1200 >>XP_016858214 (OMIM: 603427,616882) PREDICTED: period c (1203 aa) initn: 4767 init1: 4767 opt: 8059 Z-score: 3514.1 bits: 662.3 E(85289): 5.4e-189 Smith-Waterman score: 8059; 99.3% identity (99.3% similar) in 1210 aa overlap (1-1210:1-1203) 10 20 30 40 50 60 pF1KA1 MPRGEAPGPGRRGAKDEALGEESGERWSPEFHLQRKLADSSHSEQQDRNRVSEELIMVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPRGEAPGPGRRGAKDEALGEESGERWSPEFHLQRKLADSSHSEQQDRNRVSEELIMVVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 EMKKYFPSERRNKPSTLDALNYALRCVHSVQANSEFFQILSQNGAPQADVSMYSLEELAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMKKYFPSERRNKPSTLDALNYALRCVHSVQANSEFFQILSQNGAPQADVSMYSLEELAT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 IASEHTSKNTDTFVAVFSFLSGRLVHISEQAALILNRKKDVLASSHFVDLLAPQDMRVFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IASEHTSKNTDTFVAVFSFLSGRLVHISEQAALILNRKKDVLASSHFVDLLAPQDMRVFY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 AHTARAQLPFWNNWTQRAAARYECAPVKPFFCRIRGGEDRKQEKCHSPFRIIPYLIHVHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AHTARAQLPFWNNWTQRAAARYECAPVKPFFCRIRGGEDRKQEKCHSPFRIIPYLIHVHH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 PAQPELESEPCCLTVVEKIHSGYEAPRIPVNKRIFTTTHTPGCVFLEVDEKAVPLLGYLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAQPELESEPCCLTVVEKIHSGYEAPRIPVNKRIFTTTHTPGCVFLEVDEKAVPLLGYLP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 QDLIGTSILSYLHPEDRSLMVAIHQKVLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QDLIGTSILSYLHPEDRSLMVAIHQKVLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 VNPWSRKISFIIGRHKVRTSPLNEDVFATKIKKMNDNDKDITELQEQIYKLLLQPVHVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNPWSRKISFIIGRHKVRTSPLNEDVFATKIKKMNDNDKDITELQEQIYKLLLQPVHVSV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 SSGYGSLGSSGSQEQLVSIASSSEASGHRVEETKAEQMTLQQVYASVNKIKNLGQQLYIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSGYGSLGSSGSQEQLVSIASSSEASGHRVEETKAEQMTLQQVYASVNKIKNLGQQLYIE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SMTKSSFKPVTGTRTEPNGGGESANGGGECKTFTSFHQTLKNNSVYTEPCEDLRNDEHSP :::::::::::::::::::::: ::::::::::::::::::::::::::::::: XP_016 SMTKSSFKPVTGTRTEPNGGGE-------CKTFTSFHQTLKNNSVYTEPCEDLRNDEHSP 490 500 510 520 530 550 560 570 580 590 600 pF1KA1 SYQQINCIDSVIRYLKSYNIPALKRKCISCTNTTSSSSEEDKQNHKADDVQALQAGLQIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SYQQINCIDSVIRYLKSYNIPALKRKCISCTNTTSSSSEEDKQNHKADDVQALQAGLQIP 540 550 560 570 580 590 610 620 630 640 650 660 pF1KA1 AIPKSEMPTNGRSIDTGGGAPQILSTAMLSLGSGISQCGYSSTIVHVPPPETARDATLFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIPKSEMPTNGRSIDTGGGAPQILSTAMLSLGSGISQCGYSSTIVHVPPPETARDATLFC 600 610 620 630 640 650 670 680 690 700 710 720 pF1KA1 EPWTLNMQPAPLTSEEFKHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPWTLNMQPAPLTSEEFKHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESR 660 670 680 690 700 710 730 740 750 760 770 780 pF1KA1 SKAKYSYFQGDSTSKQTRSAGCRKGKHKRKKLPEPPDSSSSNTGSGPRRGAHQNAQPCCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKAKYSYFQGDSTSKQTRSAGCRKGKHKRKKLPEPPDSSSSNTGSGPRRGAHQNAQPCCP 720 730 740 750 760 770 790 800 810 820 830 840 pF1KA1 SAASSPHTSSPTFPPAAMVPSQAPYLVPAFPLPAATSPGREYAAPGTAPEGLHGPPLSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_016 SAASSPHTSSPTFPPAAMVPSQAPYLVPAFPLPAATSPGREYAAPGTAPEGLHGLPLSEG 780 790 800 810 820 830 850 860 870 880 890 900 pF1KA1 LQPYPAFPFPYLDTFMTVFLPDPPVCPLLSPSFLPCPFLGATASSAISPSMSSAMSPTLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQPYPAFPFPYLDTFMTVFLPDPPVCPLLSPSFLPCPFLGATASSAISPSMSSAMSPTLD 840 850 860 870 880 890 910 920 930 940 950 960 pF1KA1 PPPSVTSQRREEEKWEAQSEGHPFITSRSSSPLQLNLLQEEMPRPSESPDRMRRNTCPQT ::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::: XP_016 PPPSVTSQRREEEKWEAQSEGHPFITSRSSSPLQLNLLQEEMPRPSESPDQMRRNTCPQT 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KA1 EYQCVTGNNGSESSPATTGALSTGSPPRENPSHPTASALSTGSPPMKNPSHPTASALSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EYQCVTGNNGSESSPATTGALSTGSPPRENPSHPTASALSTGSPPMKNPSHPTASALSTG 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KA1 SPPMKNPSHPTASTLSMGLPPSRTPSHPTATVLSTGSPPSESPSRTGSAASGSSDSSIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPPMKNPSHPTASTLSMGLPPSRTPSHPTATVLSTGSPPSESPSRTGSAASGSSDSSIYL 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KA1 TSSVYSSKISQNGQQSQDVQKKETFPNVAEEPIWRMIRQTPERILMTYQVPERVKEVVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSSVYSSKISQNGQQSQDVQKKETFPNVAEEPIWRMIRQTPERILMTYQVPERVKEVVLK 1080 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 pF1KA1 EDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTCENEDSADGAATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTCENEDSADGAATS 1140 1150 1160 1170 1180 1190 1210 pF1KA1 CGQVLVEDSC :::::::::: XP_016 CGQVLVEDSC 1200 >>XP_016858215 (OMIM: 603427,616882) PREDICTED: period c (1202 aa) initn: 6065 init1: 4767 opt: 8042 Z-score: 3506.7 bits: 660.9 E(85289): 1.4e-188 Smith-Waterman score: 8042; 99.2% identity (99.3% similar) in 1210 aa overlap (1-1210:1-1202) 10 20 30 40 50 60 pF1KA1 MPRGEAPGPGRRGAKDEALGEESGERWSPEFHLQRKLADSSHSEQQDRNRVSEELIMVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPRGEAPGPGRRGAKDEALGEESGERWSPEFHLQRKLADSSHSEQQDRNRVSEELIMVVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 EMKKYFPSERRNKPSTLDALNYALRCVHSVQANSEFFQILSQNGAPQADVSMYSLEELAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMKKYFPSERRNKPSTLDALNYALRCVHSVQANSEFFQILSQNGAPQADVSMYSLEELAT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 IASEHTSKNTDTFVAVFSFLSGRLVHISEQAALILNRKKDVLASSHFVDLLAPQDMRVFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IASEHTSKNTDTFVAVFSFLSGRLVHISEQAALILNRKKDVLASSHFVDLLAPQDMRVFY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 AHTARAQLPFWNNWTQRAAARYECAPVKPFFCRIRGGEDRKQEKCHSPFRIIPYLIHVHH ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_016 AHTARAQLPFWNNWTQRAA-RYECAPVKPFFCRIRGGEDRKQEKCHSPFRIIPYLIHVHH 190 200 210 220 230 250 260 270 280 290 300 pF1KA1 PAQPELESEPCCLTVVEKIHSGYEAPRIPVNKRIFTTTHTPGCVFLEVDEKAVPLLGYLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAQPELESEPCCLTVVEKIHSGYEAPRIPVNKRIFTTTHTPGCVFLEVDEKAVPLLGYLP 240 250 260 270 280 290 310 320 330 340 350 360 pF1KA1 QDLIGTSILSYLHPEDRSLMVAIHQKVLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QDLIGTSILSYLHPEDRSLMVAIHQKVLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSF 300 310 320 330 340 350 370 380 390 400 410 420 pF1KA1 VNPWSRKISFIIGRHKVRTSPLNEDVFATKIKKMNDNDKDITELQEQIYKLLLQPVHVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNPWSRKISFIIGRHKVRTSPLNEDVFATKIKKMNDNDKDITELQEQIYKLLLQPVHVSV 360 370 380 390 400 410 430 440 450 460 470 480 pF1KA1 SSGYGSLGSSGSQEQLVSIASSSEASGHRVEETKAEQMTLQQVYASVNKIKNLGQQLYIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSGYGSLGSSGSQEQLVSIASSSEASGHRVEETKAEQMTLQQVYASVNKIKNLGQQLYIE 420 430 440 450 460 470 490 500 510 520 530 540 pF1KA1 SMTKSSFKPVTGTRTEPNGGGESANGGGECKTFTSFHQTLKNNSVYTEPCEDLRNDEHSP :::::::::::::::::::::: ::::::::::::::::::::::::::::::: XP_016 SMTKSSFKPVTGTRTEPNGGGE-------CKTFTSFHQTLKNNSVYTEPCEDLRNDEHSP 480 490 500 510 520 530 550 560 570 580 590 600 pF1KA1 SYQQINCIDSVIRYLKSYNIPALKRKCISCTNTTSSSSEEDKQNHKADDVQALQAGLQIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SYQQINCIDSVIRYLKSYNIPALKRKCISCTNTTSSSSEEDKQNHKADDVQALQAGLQIP 540 550 560 570 580 590 610 620 630 640 650 660 pF1KA1 AIPKSEMPTNGRSIDTGGGAPQILSTAMLSLGSGISQCGYSSTIVHVPPPETARDATLFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIPKSEMPTNGRSIDTGGGAPQILSTAMLSLGSGISQCGYSSTIVHVPPPETARDATLFC 600 610 620 630 640 650 670 680 690 700 710 720 pF1KA1 EPWTLNMQPAPLTSEEFKHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPWTLNMQPAPLTSEEFKHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESR 660 670 680 690 700 710 730 740 750 760 770 780 pF1KA1 SKAKYSYFQGDSTSKQTRSAGCRKGKHKRKKLPEPPDSSSSNTGSGPRRGAHQNAQPCCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKAKYSYFQGDSTSKQTRSAGCRKGKHKRKKLPEPPDSSSSNTGSGPRRGAHQNAQPCCP 720 730 740 750 760 770 790 800 810 820 830 840 pF1KA1 SAASSPHTSSPTFPPAAMVPSQAPYLVPAFPLPAATSPGREYAAPGTAPEGLHGPPLSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_016 SAASSPHTSSPTFPPAAMVPSQAPYLVPAFPLPAATSPGREYAAPGTAPEGLHGLPLSEG 780 790 800 810 820 830 850 860 870 880 890 900 pF1KA1 LQPYPAFPFPYLDTFMTVFLPDPPVCPLLSPSFLPCPFLGATASSAISPSMSSAMSPTLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQPYPAFPFPYLDTFMTVFLPDPPVCPLLSPSFLPCPFLGATASSAISPSMSSAMSPTLD 840 850 860 870 880 890 910 920 930 940 950 960 pF1KA1 PPPSVTSQRREEEKWEAQSEGHPFITSRSSSPLQLNLLQEEMPRPSESPDRMRRNTCPQT ::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::: XP_016 PPPSVTSQRREEEKWEAQSEGHPFITSRSSSPLQLNLLQEEMPRPSESPDQMRRNTCPQT 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KA1 EYQCVTGNNGSESSPATTGALSTGSPPRENPSHPTASALSTGSPPMKNPSHPTASALSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EYQCVTGNNGSESSPATTGALSTGSPPRENPSHPTASALSTGSPPMKNPSHPTASALSTG 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KA1 SPPMKNPSHPTASTLSMGLPPSRTPSHPTATVLSTGSPPSESPSRTGSAASGSSDSSIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPPMKNPSHPTASTLSMGLPPSRTPSHPTATVLSTGSPPSESPSRTGSAASGSSDSSIYL 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KA1 TSSVYSSKISQNGQQSQDVQKKETFPNVAEEPIWRMIRQTPERILMTYQVPERVKEVVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSSVYSSKISQNGQQSQDVQKKETFPNVAEEPIWRMIRQTPERILMTYQVPERVKEVVLK 1080 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 pF1KA1 EDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTCENEDSADGAATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTCENEDSADGAATS 1140 1150 1160 1170 1180 1190 1210 pF1KA1 CGQVLVEDSC :::::::::: XP_016 CGQVLVEDSC 1200 >>XP_011540692 (OMIM: 603427,616882) PREDICTED: period c (1202 aa) initn: 4973 init1: 3353 opt: 8040 Z-score: 3505.8 bits: 660.7 E(85289): 1.5e-188 Smith-Waterman score: 8040; 99.2% identity (99.3% similar) in 1210 aa overlap (1-1210:1-1202) 10 20 30 40 50 60 pF1KA1 MPRGEAPGPGRRGAKDEALGEESGERWSPEFHLQRKLADSSHSEQQDRNRVSEELIMVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPRGEAPGPGRRGAKDEALGEESGERWSPEFHLQRKLADSSHSEQQDRNRVSEELIMVVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 EMKKYFPSERRNKPSTLDALNYALRCVHSVQANSEFFQILSQNGAPQADVSMYSLEELAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMKKYFPSERRNKPSTLDALNYALRCVHSVQANSEFFQILSQNGAPQADVSMYSLEELAT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 IASEHTSKNTDTFVAVFSFLSGRLVHISEQAALILNRKKDVLASSHFVDLLAPQDMRVFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IASEHTSKNTDTFVAVFSFLSGRLVHISEQAALILNRKKDVLASSHFVDLLAPQDMRVFY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 AHTARAQLPFWNNWTQRAAARYECAPVKPFFCRIRGGEDRKQEKCHSPFRIIPYLIHVHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AHTARAQLPFWNNWTQRAAARYECAPVKPFFCRIRGGEDRKQEKCHSPFRIIPYLIHVHH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 PAQPELESEPCCLTVVEKIHSGYEAPRIPVNKRIFTTTHTPGCVFLEVDEKAVPLLGYLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAQPELESEPCCLTVVEKIHSGYEAPRIPVNKRIFTTTHTPGCVFLEVDEKAVPLLGYLP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 QDLIGTSILSYLHPEDRSLMVAIHQKVLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QDLIGTSILSYLHPEDRSLMVAIHQKVLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 VNPWSRKISFIIGRHKVRTSPLNEDVFATKIKKMNDNDKDITELQEQIYKLLLQPVHVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNPWSRKISFIIGRHKVRTSPLNEDVFATKIKKMNDNDKDITELQEQIYKLLLQPVHVSV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 SSGYGSLGSSGSQEQLVSIASSSEASGHRVEETKAEQMTLQQVYASVNKIKNLGQQLYIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSGYGSLGSSGSQEQLVSIASSSEASGHRVEETKAEQMTLQQVYASVNKIKNLGQQLYIE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SMTKSSFKPVTGTRTEPNGGGESANGGGECKTFTSFHQTLKNNSVYTEPCEDLRNDEHSP :::::::::::::::::::::: ::::::::::::::::::::::::::::::: XP_011 SMTKSSFKPVTGTRTEPNGGGE-------CKTFTSFHQTLKNNSVYTEPCEDLRNDEHSP 490 500 510 520 530 550 560 570 580 590 600 pF1KA1 SYQQINCIDSVIRYLKSYNIPALKRKCISCTNTTSSSSEEDKQNHKADDVQALQAGLQIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SYQQINCIDSVIRYLKSYNIPALKRKCISCTNTTSSSSEEDKQNHKADDVQALQAGLQIP 540 550 560 570 580 590 610 620 630 640 650 660 pF1KA1 AIPKSEMPTNGRSIDTGGGAPQILSTAMLSLGSGISQCGYSSTIVHVPPPETARDATLFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AIPKSEMPTNGRSIDTGGGAPQILSTAMLSLGSGISQCGYSSTIVHVPPPETARDATLFC 600 610 620 630 640 650 670 680 690 700 710 720 pF1KA1 EPWTLNMQPAPLTSEEFKHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPWTLNMQPAPLTSEEFKHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESR 660 670 680 690 700 710 730 740 750 760 770 780 pF1KA1 SKAKYSYFQGDSTSKQTRSAGCRKGKHKRKKLPEPPDSSSSNTGSGPRRGAHQNAQPCCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKAKYSYFQGDSTSKQTRSAGCRKGKHKRKKLPEPPDSSSSNTGSGPRRGAHQNAQPCCP 720 730 740 750 760 770 790 800 810 820 830 840 pF1KA1 SAASSPHTSSPTFPPAAMVPSQAPYLVPAFPLPAATSPGREYAAPGTAPEGLHGPPLSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_011 SAASSPHTSSPTFPPAAMVPSQAPYLVPAFPLPAATSPGREYAAPGTAPEGLHGLPLSEG 780 790 800 810 820 830 850 860 870 880 890 900 pF1KA1 LQPYPAFPFPYLDTFMTVFLPDPPVCPLLSPSFLPCPFLGATASSAISPSMSSAMSPTLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQPYPAFPFPYLDTFMTVFLPDPPVCPLLSPSFLPCPFLGATASSAISPSMSSAMSPTLD 840 850 860 870 880 890 910 920 930 940 950 960 pF1KA1 PPPSVTSQRREEEKWEAQSEGHPFITSRSSSPLQLNLLQEEMPRPSESPDRMRRNTCPQT ::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::: XP_011 PPPSVTSQRREEEKWEAQSEGHPFITSRSSSPLQLNLLQEEMPRPSESPDQMRRNTCPQT 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KA1 EYQCVTGNNGSESSPATTGALSTGSPPRENPSHPTASALSTGSPPMKNPSHPTASALSTG :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EY-CVTGNNGSESSPATTGALSTGSPPRENPSHPTASALSTGSPPMKNPSHPTASALSTG 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KA1 SPPMKNPSHPTASTLSMGLPPSRTPSHPTATVLSTGSPPSESPSRTGSAASGSSDSSIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPPMKNPSHPTASTLSMGLPPSRTPSHPTATVLSTGSPPSESPSRTGSAASGSSDSSIYL 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KA1 TSSVYSSKISQNGQQSQDVQKKETFPNVAEEPIWRMIRQTPERILMTYQVPERVKEVVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSSVYSSKISQNGQQSQDVQKKETFPNVAEEPIWRMIRQTPERILMTYQVPERVKEVVLK 1080 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 pF1KA1 EDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTCENEDSADGAATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTCENEDSADGAATS 1140 1150 1160 1170 1180 1190 1210 pF1KA1 CGQVLVEDSC :::::::::: XP_011 CGQVLVEDSC 1200 >>NP_058515 (OMIM: 603427,616882) period circadian prote (1201 aa) initn: 4573 init1: 3135 opt: 8023 Z-score: 3498.5 bits: 659.4 E(85289): 4e-188 Smith-Waterman score: 8023; 99.1% identity (99.2% similar) in 1210 aa overlap (1-1210:1-1201) 10 20 30 40 50 60 pF1KA1 MPRGEAPGPGRRGAKDEALGEESGERWSPEFHLQRKLADSSHSEQQDRNRVSEELIMVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_058 MPRGEAPGPGRRGAKDEALGEESGERWSPEFHLQRKLADSSHSEQQDRNRVSEELIMVVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 EMKKYFPSERRNKPSTLDALNYALRCVHSVQANSEFFQILSQNGAPQADVSMYSLEELAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_058 EMKKYFPSERRNKPSTLDALNYALRCVHSVQANSEFFQILSQNGAPQADVSMYSLEELAT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 IASEHTSKNTDTFVAVFSFLSGRLVHISEQAALILNRKKDVLASSHFVDLLAPQDMRVFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_058 IASEHTSKNTDTFVAVFSFLSGRLVHISEQAALILNRKKDVLASSHFVDLLAPQDMRVFY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 AHTARAQLPFWNNWTQRAAARYECAPVKPFFCRIRGGEDRKQEKCHSPFRIIPYLIHVHH ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: NP_058 AHTARAQLPFWNNWTQRAA-RYECAPVKPFFCRIRGGEDRKQEKCHSPFRIIPYLIHVHH 190 200 210 220 230 250 260 270 280 290 300 pF1KA1 PAQPELESEPCCLTVVEKIHSGYEAPRIPVNKRIFTTTHTPGCVFLEVDEKAVPLLGYLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_058 PAQPELESEPCCLTVVEKIHSGYEAPRIPVNKRIFTTTHTPGCVFLEVDEKAVPLLGYLP 240 250 260 270 280 290 310 320 330 340 350 360 pF1KA1 QDLIGTSILSYLHPEDRSLMVAIHQKVLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_058 QDLIGTSILSYLHPEDRSLMVAIHQKVLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSF 300 310 320 330 340 350 370 380 390 400 410 420 pF1KA1 VNPWSRKISFIIGRHKVRTSPLNEDVFATKIKKMNDNDKDITELQEQIYKLLLQPVHVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_058 VNPWSRKISFIIGRHKVRTSPLNEDVFATKIKKMNDNDKDITELQEQIYKLLLQPVHVSV 360 370 380 390 400 410 430 440 450 460 470 480 pF1KA1 SSGYGSLGSSGSQEQLVSIASSSEASGHRVEETKAEQMTLQQVYASVNKIKNLGQQLYIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_058 SSGYGSLGSSGSQEQLVSIASSSEASGHRVEETKAEQMTLQQVYASVNKIKNLGQQLYIE 420 430 440 450 460 470 490 500 510 520 530 540 pF1KA1 SMTKSSFKPVTGTRTEPNGGGESANGGGECKTFTSFHQTLKNNSVYTEPCEDLRNDEHSP :::::::::::::::::::::: ::::::::::::::::::::::::::::::: NP_058 SMTKSSFKPVTGTRTEPNGGGE-------CKTFTSFHQTLKNNSVYTEPCEDLRNDEHSP 480 490 500 510 520 530 550 560 570 580 590 600 pF1KA1 SYQQINCIDSVIRYLKSYNIPALKRKCISCTNTTSSSSEEDKQNHKADDVQALQAGLQIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_058 SYQQINCIDSVIRYLKSYNIPALKRKCISCTNTTSSSSEEDKQNHKADDVQALQAGLQIP 540 550 560 570 580 590 610 620 630 640 650 660 pF1KA1 AIPKSEMPTNGRSIDTGGGAPQILSTAMLSLGSGISQCGYSSTIVHVPPPETARDATLFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_058 AIPKSEMPTNGRSIDTGGGAPQILSTAMLSLGSGISQCGYSSTIVHVPPPETARDATLFC 600 610 620 630 640 650 670 680 690 700 710 720 pF1KA1 EPWTLNMQPAPLTSEEFKHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_058 EPWTLNMQPAPLTSEEFKHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESR 660 670 680 690 700 710 730 740 750 760 770 780 pF1KA1 SKAKYSYFQGDSTSKQTRSAGCRKGKHKRKKLPEPPDSSSSNTGSGPRRGAHQNAQPCCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_058 SKAKYSYFQGDSTSKQTRSAGCRKGKHKRKKLPEPPDSSSSNTGSGPRRGAHQNAQPCCP 720 730 740 750 760 770 790 800 810 820 830 840 pF1KA1 SAASSPHTSSPTFPPAAMVPSQAPYLVPAFPLPAATSPGREYAAPGTAPEGLHGPPLSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: NP_058 SAASSPHTSSPTFPPAAMVPSQAPYLVPAFPLPAATSPGREYAAPGTAPEGLHGLPLSEG 780 790 800 810 820 830 850 860 870 880 890 900 pF1KA1 LQPYPAFPFPYLDTFMTVFLPDPPVCPLLSPSFLPCPFLGATASSAISPSMSSAMSPTLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_058 LQPYPAFPFPYLDTFMTVFLPDPPVCPLLSPSFLPCPFLGATASSAISPSMSSAMSPTLD 840 850 860 870 880 890 910 920 930 940 950 960 pF1KA1 PPPSVTSQRREEEKWEAQSEGHPFITSRSSSPLQLNLLQEEMPRPSESPDRMRRNTCPQT ::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::: NP_058 PPPSVTSQRREEEKWEAQSEGHPFITSRSSSPLQLNLLQEEMPRPSESPDQMRRNTCPQT 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KA1 EYQCVTGNNGSESSPATTGALSTGSPPRENPSHPTASALSTGSPPMKNPSHPTASALSTG :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_058 EY-CVTGNNGSESSPATTGALSTGSPPRENPSHPTASALSTGSPPMKNPSHPTASALSTG 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KA1 SPPMKNPSHPTASTLSMGLPPSRTPSHPTATVLSTGSPPSESPSRTGSAASGSSDSSIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_058 SPPMKNPSHPTASTLSMGLPPSRTPSHPTATVLSTGSPPSESPSRTGSAASGSSDSSIYL 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KA1 TSSVYSSKISQNGQQSQDVQKKETFPNVAEEPIWRMIRQTPERILMTYQVPERVKEVVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_058 TSSVYSSKISQNGQQSQDVQKKETFPNVAEEPIWRMIRQTPERILMTYQVPERVKEVVLK 1080 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 pF1KA1 EDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTCENEDSADGAATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_058 EDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTCENEDSADGAATS 1140 1150 1160 1170 1180 1190 1210 pF1KA1 CGQVLVEDSC :::::::::: NP_058 CGQVLVEDSC 1200 >>XP_005263581 (OMIM: 603427,616882) PREDICTED: period c (1203 aa) initn: 8376 init1: 7951 opt: 7951 Z-score: 3467.2 bits: 653.6 E(85289): 2.2e-186 Smith-Waterman score: 7951; 99.4% identity (99.7% similar) in 1190 aa overlap (1-1190:1-1190) 10 20 30 40 50 60 pF1KA1 MPRGEAPGPGRRGAKDEALGEESGERWSPEFHLQRKLADSSHSEQQDRNRVSEELIMVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MPRGEAPGPGRRGAKDEALGEESGERWSPEFHLQRKLADSSHSEQQDRNRVSEELIMVVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 EMKKYFPSERRNKPSTLDALNYALRCVHSVQANSEFFQILSQNGAPQADVSMYSLEELAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EMKKYFPSERRNKPSTLDALNYALRCVHSVQANSEFFQILSQNGAPQADVSMYSLEELAT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 IASEHTSKNTDTFVAVFSFLSGRLVHISEQAALILNRKKDVLASSHFVDLLAPQDMRVFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IASEHTSKNTDTFVAVFSFLSGRLVHISEQAALILNRKKDVLASSHFVDLLAPQDMRVFY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 AHTARAQLPFWNNWTQRAAARYECAPVKPFFCRIRGGEDRKQEKCHSPFRIIPYLIHVHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AHTARAQLPFWNNWTQRAAARYECAPVKPFFCRIRGGEDRKQEKCHSPFRIIPYLIHVHH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 PAQPELESEPCCLTVVEKIHSGYEAPRIPVNKRIFTTTHTPGCVFLEVDEKAVPLLGYLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PAQPELESEPCCLTVVEKIHSGYEAPRIPVNKRIFTTTHTPGCVFLEVDEKAVPLLGYLP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 QDLIGTSILSYLHPEDRSLMVAIHQKVLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QDLIGTSILSYLHPEDRSLMVAIHQKVLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 VNPWSRKISFIIGRHKVRTSPLNEDVFATKIKKMNDNDKDITELQEQIYKLLLQPVHVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VNPWSRKISFIIGRHKVRTSPLNEDVFATKIKKMNDNDKDITELQEQIYKLLLQPVHVSV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 SSGYGSLGSSGSQEQLVSIASSSEASGHRVEETKAEQMTLQQVYASVNKIKNLGQQLYIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSGYGSLGSSGSQEQLVSIASSSEASGHRVEETKAEQMTLQQVYASVNKIKNLGQQLYIE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SMTKSSFKPVTGTRTEPNGGGESANGGGECKTFTSFHQTLKNNSVYTEPCEDLRNDEHSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SMTKSSFKPVTGTRTEPNGGGESANGGGECKTFTSFHQTLKNNSVYTEPCEDLRNDEHSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SYQQINCIDSVIRYLKSYNIPALKRKCISCTNTTSSSSEEDKQNHKADDVQALQAGLQIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SYQQINCIDSVIRYLKSYNIPALKRKCISCTNTTSSSSEEDKQNHKADDVQALQAGLQIP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 AIPKSEMPTNGRSIDTGGGAPQILSTAMLSLGSGISQCGYSSTIVHVPPPETARDATLFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AIPKSEMPTNGRSIDTGGGAPQILSTAMLSLGSGISQCGYSSTIVHVPPPETARDATLFC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 EPWTLNMQPAPLTSEEFKHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EPWTLNMQPAPLTSEEFKHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 SKAKYSYFQGDSTSKQTRSAGCRKGKHKRKKLPEPPDSSSSNTGSGPRRGAHQNAQPCCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SKAKYSYFQGDSTSKQTRSAGCRKGKHKRKKLPEPPDSSSSNTGSGPRRGAHQNAQPCCP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 SAASSPHTSSPTFPPAAMVPSQAPYLVPAFPLPAATSPGREYAAPGTAPEGLHGPPLSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_005 SAASSPHTSSPTFPPAAMVPSQAPYLVPAFPLPAATSPGREYAAPGTAPEGLHGLPLSEG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 LQPYPAFPFPYLDTFMTVFLPDPPVCPLLSPSFLPCPFLGATASSAISPSMSSAMSPTLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQPYPAFPFPYLDTFMTVFLPDPPVCPLLSPSFLPCPFLGATASSAISPSMSSAMSPTLD 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 PPPSVTSQRREEEKWEAQSEGHPFITSRSSSPLQLNLLQEEMPRPSESPDRMRRNTCPQT ::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::: XP_005 PPPSVTSQRREEEKWEAQSEGHPFITSRSSSPLQLNLLQEEMPRPSESPDQMRRNTCPQT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 EYQCVTGNNGSESSPATTGALSTGSPPRENPSHPTASALSTGSPPMKNPSHPTASALSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EYQCVTGNNGSESSPATTGALSTGSPPRENPSHPTASALSTGSPPMKNPSHPTASALSTG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 SPPMKNPSHPTASTLSMGLPPSRTPSHPTATVLSTGSPPSESPSRTGSAASGSSDSSIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPPMKNPSHPTASTLSMGLPPSRTPSHPTATVLSTGSPPSESPSRTGSAASGSSDSSIYL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 TSSVYSSKISQNGQQSQDVQKKETFPNVAEEPIWRMIRQTPERILMTYQVPERVKEVVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSSVYSSKISQNGQQSQDVQKKETFPNVAEEPIWRMIRQTPERILMTYQVPERVKEVVLK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 EDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTCENEDSADGAATS :::::::::::::::::::::::::::::::::::::::::::. .: : XP_005 EDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQVTLTSSNSPALFFFGGL 1150 1160 1170 1180 1190 1200 1210 pF1KA1 CGQVLVEDSC XP_005 CHL >>XP_016858216 (OMIM: 603427,616882) PREDICTED: period c (1154 aa) initn: 7745 init1: 7745 opt: 7745 Z-score: 3378.2 bits: 637.1 E(85289): 2e-181 Smith-Waterman score: 7745; 99.8% identity (99.9% similar) in 1154 aa overlap (57-1210:1-1154) 30 40 50 60 70 80 pF1KA1 WSPEFHLQRKLADSSHSEQQDRNRVSEELIMVVQEMKKYFPSERRNKPSTLDALNYALRC :::::::::::::::::::::::::::::: XP_016 MVVQEMKKYFPSERRNKPSTLDALNYALRC 10 20 30 90 100 110 120 130 140 pF1KA1 VHSVQANSEFFQILSQNGAPQADVSMYSLEELATIASEHTSKNTDTFVAVFSFLSGRLVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VHSVQANSEFFQILSQNGAPQADVSMYSLEELATIASEHTSKNTDTFVAVFSFLSGRLVH 40 50 60 70 80 90 150 160 170 180 190 200 pF1KA1 ISEQAALILNRKKDVLASSHFVDLLAPQDMRVFYAHTARAQLPFWNNWTQRAAARYECAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISEQAALILNRKKDVLASSHFVDLLAPQDMRVFYAHTARAQLPFWNNWTQRAAARYECAP 100 110 120 130 140 150 210 220 230 240 250 260 pF1KA1 VKPFFCRIRGGEDRKQEKCHSPFRIIPYLIHVHHPAQPELESEPCCLTVVEKIHSGYEAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKPFFCRIRGGEDRKQEKCHSPFRIIPYLIHVHHPAQPELESEPCCLTVVEKIHSGYEAP 160 170 180 190 200 210 270 280 290 300 310 320 pF1KA1 RIPVNKRIFTTTHTPGCVFLEVDEKAVPLLGYLPQDLIGTSILSYLHPEDRSLMVAIHQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIPVNKRIFTTTHTPGCVFLEVDEKAVPLLGYLPQDLIGTSILSYLHPEDRSLMVAIHQK 220 230 240 250 260 270 330 340 350 360 370 380 pF1KA1 VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKISFIIGRHKVRTSPLNEDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKISFIIGRHKVRTSPLNEDV 280 290 300 310 320 330 390 400 410 420 430 440 pF1KA1 FATKIKKMNDNDKDITELQEQIYKLLLQPVHVSVSSGYGSLGSSGSQEQLVSIASSSEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FATKIKKMNDNDKDITELQEQIYKLLLQPVHVSVSSGYGSLGSSGSQEQLVSIASSSEAS 340 350 360 370 380 390 450 460 470 480 490 500 pF1KA1 GHRVEETKAEQMTLQQVYASVNKIKNLGQQLYIESMTKSSFKPVTGTRTEPNGGGESANG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHRVEETKAEQMTLQQVYASVNKIKNLGQQLYIESMTKSSFKPVTGTRTEPNGGGESANG 400 410 420 430 440 450 510 520 530 540 550 560 pF1KA1 GGECKTFTSFHQTLKNNSVYTEPCEDLRNDEHSPSYQQINCIDSVIRYLKSYNIPALKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGECKTFTSFHQTLKNNSVYTEPCEDLRNDEHSPSYQQINCIDSVIRYLKSYNIPALKRK 460 470 480 490 500 510 570 580 590 600 610 620 pF1KA1 CISCTNTTSSSSEEDKQNHKADDVQALQAGLQIPAIPKSEMPTNGRSIDTGGGAPQILST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CISCTNTTSSSSEEDKQNHKADDVQALQAGLQIPAIPKSEMPTNGRSIDTGGGAPQILST 520 530 540 550 560 570 630 640 650 660 670 680 pF1KA1 AMLSLGSGISQCGYSSTIVHVPPPETARDATLFCEPWTLNMQPAPLTSEEFKHVGLTAAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AMLSLGSGISQCGYSSTIVHVPPPETARDATLFCEPWTLNMQPAPLTSEEFKHVGLTAAV 580 590 600 610 620 630 690 700 710 720 730 740 pF1KA1 LSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRSKAKYSYFQGDSTSKQTRSAGCRKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRSKAKYSYFQGDSTSKQTRSAGCRKGK 640 650 660 670 680 690 750 760 770 780 790 800 pF1KA1 HKRKKLPEPPDSSSSNTGSGPRRGAHQNAQPCCPSAASSPHTSSPTFPPAAMVPSQAPYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HKRKKLPEPPDSSSSNTGSGPRRGAHQNAQPCCPSAASSPHTSSPTFPPAAMVPSQAPYL 700 710 720 730 740 750 810 820 830 840 850 860 pF1KA1 VPAFPLPAATSPGREYAAPGTAPEGLHGPPLSEGLQPYPAFPFPYLDTFMTVFLPDPPVC :::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::: XP_016 VPAFPLPAATSPGREYAAPGTAPEGLHGLPLSEGLQPYPAFPFPYLDTFMTVFLPDPPVC 760 770 780 790 800 810 870 880 890 900 910 920 pF1KA1 PLLSPSFLPCPFLGATASSAISPSMSSAMSPTLDPPPSVTSQRREEEKWEAQSEGHPFIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLLSPSFLPCPFLGATASSAISPSMSSAMSPTLDPPPSVTSQRREEEKWEAQSEGHPFIT 820 830 840 850 860 870 930 940 950 960 970 980 pF1KA1 SRSSSPLQLNLLQEEMPRPSESPDRMRRNTCPQTEYQCVTGNNGSESSPATTGALSTGSP ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: XP_016 SRSSSPLQLNLLQEEMPRPSESPDQMRRNTCPQTEYQCVTGNNGSESSPATTGALSTGSP 880 890 900 910 920 930 990 1000 1010 1020 1030 1040 pF1KA1 PRENPSHPTASALSTGSPPMKNPSHPTASALSTGSPPMKNPSHPTASTLSMGLPPSRTPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRENPSHPTASALSTGSPPMKNPSHPTASALSTGSPPMKNPSHPTASTLSMGLPPSRTPS 940 950 960 970 980 990 1050 1060 1070 1080 1090 1100 pF1KA1 HPTATVLSTGSPPSESPSRTGSAASGSSDSSIYLTSSVYSSKISQNGQQSQDVQKKETFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HPTATVLSTGSPPSESPSRTGSAASGSSDSSIYLTSSVYSSKISQNGQQSQDVQKKETFP 1000 1010 1020 1030 1040 1050 1110 1120 1130 1140 1150 1160 pF1KA1 NVAEEPIWRMIRQTPERILMTYQVPERVKEVVLKEDLEKLESMRQQQPQFSHGQKEELAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NVAEEPIWRMIRQTPERILMTYQVPERVKEVVLKEDLEKLESMRQQQPQFSHGQKEELAK 1060 1070 1080 1090 1100 1110 1170 1180 1190 1200 1210 pF1KA1 VYNWIQSQTVTQEIDIQACVTCENEDSADGAATSCGQVLVEDSC :::::::::::::::::::::::::::::::::::::::::::: XP_016 VYNWIQSQTVTQEIDIQACVTCENEDSADGAATSCGQVLVEDSC 1120 1130 1140 1150 1210 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 01:49:45 2016 done: Fri Nov 4 01:49:47 2016 Total Scan time: 13.710 Total Display time: 0.530 Function used was FASTA [36.3.4 Apr, 2011]