Result of FASTA (omim) for
pF1KA1780
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1780, 1140 aa
1>>>pF1KA1780 1140 - 1140 aa - 1140 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1704+/-0.000607; mu= 15.7545+/- 0.038
mean_var=341.5615+/-67.558, 0's: 0 Z-trim(115.9): 566 B-trim: 36 in 1/53
Lambda= 0.069397
statistics sampled from 26017 (26669) to 26017 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.63), E-opt: 0.2 (0.313), width: 16
Scan time: 12.180
The best scores are: opt bits E(85289)
NP_115822 (OMIM: 612453,614399) multiple epidermal (1140) 8809 898.1 0
NP_001243474 (OMIM: 612453,614399) multiple epider (1140) 8809 898.1 0
XP_011541996 (OMIM: 612453,614399) PREDICTED: mult (1140) 8809 898.1 0
XP_016865476 (OMIM: 612453,614399) PREDICTED: mult (1195) 8809 898.2 0
XP_016865477 (OMIM: 612453,614399) PREDICTED: mult ( 760) 5752 591.8 5.3e-168
XP_016878160 (OMIM: 612454) PREDICTED: multiple ep (1092) 5273 544.1 1.7e-153
XP_016878162 (OMIM: 612454) PREDICTED: multiple ep (1021) 5271 543.8 1.9e-153
NP_115821 (OMIM: 612454) multiple epidermal growth (1044) 5224 539.1 5.1e-152
XP_016878161 (OMIM: 612454) PREDICTED: multiple ep (1044) 5224 539.1 5.1e-152
NP_001295048 (OMIM: 612453,614399) multiple epider ( 567) 4568 473.0 2.2e-132
NP_001295050 (OMIM: 612453,614399) multiple epider ( 567) 4568 473.0 2.2e-132
XP_016878159 (OMIM: 612454) PREDICTED: multiple ep (1097) 4503 467.0 2.8e-130
XP_016856725 (OMIM: 610278) PREDICTED: platelet en (1037) 3159 332.4 8.8e-90
NP_001073940 (OMIM: 610278) platelet endothelial a (1037) 3159 332.4 8.8e-90
XP_011507812 (OMIM: 610278) PREDICTED: platelet en (1037) 3159 332.4 8.8e-90
XP_005245198 (OMIM: 610278) PREDICTED: platelet en (1037) 3159 332.4 8.8e-90
XP_011507813 (OMIM: 610278) PREDICTED: platelet en (1002) 3040 320.5 3.3e-86
XP_016856728 (OMIM: 610278) PREDICTED: platelet en ( 973) 3033 319.7 5.3e-86
XP_016856726 (OMIM: 610278) PREDICTED: platelet en ( 973) 3033 319.7 5.3e-86
XP_016856727 (OMIM: 610278) PREDICTED: platelet en ( 973) 3033 319.7 5.3e-86
XP_016856723 (OMIM: 610278) PREDICTED: platelet en (1125) 3033 319.8 5.7e-86
XP_016856730 (OMIM: 610278) PREDICTED: platelet en ( 909) 2569 273.2 5e-72
XP_016856729 (OMIM: 610278) PREDICTED: platelet en ( 909) 2569 273.2 5e-72
XP_016856731 (OMIM: 610278) PREDICTED: platelet en ( 909) 2569 273.2 5e-72
XP_016856724 (OMIM: 610278) PREDICTED: platelet en (1081) 2409 257.3 3.6e-67
XP_011507814 (OMIM: 610278) PREDICTED: platelet en ( 868) 2398 256.1 6.9e-67
XP_011539188 (OMIM: 604266) PREDICTED: multiple ep (1560) 2350 251.7 2.6e-65
XP_016878164 (OMIM: 612454) PREDICTED: multiple ep ( 854) 2287 245.0 1.5e-63
XP_016878163 (OMIM: 612454) PREDICTED: multiple ep ( 854) 2287 245.0 1.5e-63
XP_011539189 (OMIM: 604266) PREDICTED: multiple ep (1395) 2276 244.2 4.2e-63
XP_006710469 (OMIM: 604266) PREDICTED: multiple ep (1436) 2276 244.2 4.2e-63
NP_001400 (OMIM: 604266) multiple epidermal growth (1541) 2276 244.3 4.4e-63
XP_016856022 (OMIM: 604266) PREDICTED: multiple ep (1559) 2276 244.3 4.4e-63
XP_011539187 (OMIM: 604266) PREDICTED: multiple ep (1603) 2276 244.3 4.5e-63
XP_011539190 (OMIM: 604266) PREDICTED: multiple ep (1364) 2242 240.8 4.4e-62
NP_663325 (OMIM: 607873) scavenger receptor class ( 569) 950 110.8 2.5e-23
NP_003684 (OMIM: 607873) scavenger receptor class ( 830) 950 111.1 3e-23
XP_005270958 (OMIM: 102500,600275,610205) PREDICTE (2432) 880 104.8 6.5e-21
XP_011539822 (OMIM: 102500,600275,610205) PREDICTE (2432) 880 104.8 6.5e-21
XP_016856862 (OMIM: 102500,600275,610205) PREDICTE (2432) 880 104.8 6.5e-21
XP_016856861 (OMIM: 102500,600275,610205) PREDICTE (2455) 880 104.8 6.5e-21
XP_011539821 (OMIM: 102500,600275,610205) PREDICTE (2467) 880 104.9 6.5e-21
NP_077719 (OMIM: 102500,600275,610205) neurogenic (2471) 880 104.9 6.6e-21
XP_016884554 (OMIM: 600920,613619) PREDICTED: scav ( 617) 838 99.6 6.1e-20
NP_878315 (OMIM: 600920,613619) scavenger receptor ( 866) 838 99.9 7.2e-20
NP_699165 (OMIM: 600920,613619) scavenger receptor ( 871) 838 99.9 7.2e-20
NP_002217 (OMIM: 602570) protein jagged-2 isoform (1238) 830 99.3 1.5e-19
NP_001186930 (OMIM: 102500,600275,610205) neurogen (1235) 826 98.9 2e-19
NP_061978 (OMIM: 600985,606408,615963) tenascin-X (4242) 806 97.8 1.5e-18
NP_660142 (OMIM: 602570) protein jagged-2 isoform (1200) 754 91.7 2.9e-17
>>NP_115822 (OMIM: 612453,614399) multiple epidermal gro (1140 aa)
initn: 8809 init1: 8809 opt: 8809 Z-score: 4789.6 bits: 898.1 E(85289): 0
Smith-Waterman score: 8809; 100.0% identity (100.0% similar) in 1140 aa overlap (1-1140:1-1140)
10 20 30 40 50 60
pF1KA1 MVISLNSCLSFICLLLCHWIGTASPLNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MVISLNSCLSFICLLLCHWIGTASPLNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 TDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 TDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 PNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 PNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 RCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 RCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 QNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 QNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 GYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 GYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 GIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 GIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGAD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 CDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 CDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 DCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 DCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 RCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 RCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGIC
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 ECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 ECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVC
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 PSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 PSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHN
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 GAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 GAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 MGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 SLSRTSTALPADSYQIGAIAGIIILVLVVLFLLALFIIYRHKQKGKESSMPAVTYTPAMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 SLSRTSTALPADSYQIGAIAGIIILVLVVLFLLALFIIYRHKQKGKESSMPAVTYTPAMR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 VVNADYTISGTLPHSNGGNANSHYFTNPSYHTLTQCATSPHVNNRDRMTVTKSKNNQLFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 VVNADYTISGTLPHSNGGNANSHYFTNPSYHTLTQCATSPHVNNRDRMTVTKSKNNQLFV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA1 NLKNVNPGKRGPVGDCTGTLPADWKHGGYLNELGAFGLDRSYMGKSLKDLGKNSEYNSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 NLKNVNPGKRGPVGDCTGTLPADWKHGGYLNELGAFGLDRSYMGKSLKDLGKNSEYNSSN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA1 CSLSSSENPYATIKDPPVLIPKSSECGYVEMKSPARRDSPYAEINNSTSANRNVYEVEPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 CSLSSSENPYATIKDPPVLIPKSSECGYVEMKSPARRDSPYAEINNSTSANRNVYEVEPT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA1 VSVVQGVFSNNGRLSQDPYDLPKNSHIPCHYDLLPVRDSSSSPKQEDSGGSSSNSSSSSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 VSVVQGVFSNNGRLSQDPYDLPKNSHIPCHYDLLPVRDSSSSPKQEDSGGSSSNSSSSSE
1090 1100 1110 1120 1130 1140
>>NP_001243474 (OMIM: 612453,614399) multiple epidermal (1140 aa)
initn: 8809 init1: 8809 opt: 8809 Z-score: 4789.6 bits: 898.1 E(85289): 0
Smith-Waterman score: 8809; 100.0% identity (100.0% similar) in 1140 aa overlap (1-1140:1-1140)
10 20 30 40 50 60
pF1KA1 MVISLNSCLSFICLLLCHWIGTASPLNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVISLNSCLSFICLLLCHWIGTASPLNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 TDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 PNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 RCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 QNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 GYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 GIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGAD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 CDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 DCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 RCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGIC
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 ECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVC
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 PSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHN
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 GAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 MGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 SLSRTSTALPADSYQIGAIAGIIILVLVVLFLLALFIIYRHKQKGKESSMPAVTYTPAMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLSRTSTALPADSYQIGAIAGIIILVLVVLFLLALFIIYRHKQKGKESSMPAVTYTPAMR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 VVNADYTISGTLPHSNGGNANSHYFTNPSYHTLTQCATSPHVNNRDRMTVTKSKNNQLFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVNADYTISGTLPHSNGGNANSHYFTNPSYHTLTQCATSPHVNNRDRMTVTKSKNNQLFV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA1 NLKNVNPGKRGPVGDCTGTLPADWKHGGYLNELGAFGLDRSYMGKSLKDLGKNSEYNSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLKNVNPGKRGPVGDCTGTLPADWKHGGYLNELGAFGLDRSYMGKSLKDLGKNSEYNSSN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA1 CSLSSSENPYATIKDPPVLIPKSSECGYVEMKSPARRDSPYAEINNSTSANRNVYEVEPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSLSSSENPYATIKDPPVLIPKSSECGYVEMKSPARRDSPYAEINNSTSANRNVYEVEPT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA1 VSVVQGVFSNNGRLSQDPYDLPKNSHIPCHYDLLPVRDSSSSPKQEDSGGSSSNSSSSSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSVVQGVFSNNGRLSQDPYDLPKNSHIPCHYDLLPVRDSSSSPKQEDSGGSSSNSSSSSE
1090 1100 1110 1120 1130 1140
>>XP_011541996 (OMIM: 612453,614399) PREDICTED: multiple (1140 aa)
initn: 8809 init1: 8809 opt: 8809 Z-score: 4789.6 bits: 898.1 E(85289): 0
Smith-Waterman score: 8809; 100.0% identity (100.0% similar) in 1140 aa overlap (1-1140:1-1140)
10 20 30 40 50 60
pF1KA1 MVISLNSCLSFICLLLCHWIGTASPLNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVISLNSCLSFICLLLCHWIGTASPLNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 TDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 PNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 RCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 QNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 GYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 GIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGAD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 CDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 DCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 RCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGIC
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 ECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVC
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 PSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHN
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 GAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 MGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 SLSRTSTALPADSYQIGAIAGIIILVLVVLFLLALFIIYRHKQKGKESSMPAVTYTPAMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLSRTSTALPADSYQIGAIAGIIILVLVVLFLLALFIIYRHKQKGKESSMPAVTYTPAMR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 VVNADYTISGTLPHSNGGNANSHYFTNPSYHTLTQCATSPHVNNRDRMTVTKSKNNQLFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVNADYTISGTLPHSNGGNANSHYFTNPSYHTLTQCATSPHVNNRDRMTVTKSKNNQLFV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA1 NLKNVNPGKRGPVGDCTGTLPADWKHGGYLNELGAFGLDRSYMGKSLKDLGKNSEYNSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLKNVNPGKRGPVGDCTGTLPADWKHGGYLNELGAFGLDRSYMGKSLKDLGKNSEYNSSN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA1 CSLSSSENPYATIKDPPVLIPKSSECGYVEMKSPARRDSPYAEINNSTSANRNVYEVEPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSLSSSENPYATIKDPPVLIPKSSECGYVEMKSPARRDSPYAEINNSTSANRNVYEVEPT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA1 VSVVQGVFSNNGRLSQDPYDLPKNSHIPCHYDLLPVRDSSSSPKQEDSGGSSSNSSSSSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSVVQGVFSNNGRLSQDPYDLPKNSHIPCHYDLLPVRDSSSSPKQEDSGGSSSNSSSSSE
1090 1100 1110 1120 1130 1140
>>XP_016865476 (OMIM: 612453,614399) PREDICTED: multiple (1195 aa)
initn: 8809 init1: 8809 opt: 8809 Z-score: 4789.5 bits: 898.2 E(85289): 0
Smith-Waterman score: 8809; 100.0% identity (100.0% similar) in 1140 aa overlap (1-1140:56-1195)
10 20 30
pF1KA1 MVISLNSCLSFICLLLCHWIGTASPLNLED
::::::::::::::::::::::::::::::
XP_016 WISNKCATMEFVESWTEPALGFCRVVLQKKMVISLNSCLSFICLLLCHWIGTASPLNLED
30 40 50 60 70 80
40 50 60 70 80 90
pF1KA1 PNVCSHWESYSVTVQESYPHPFDQIYYTSCTDILNWFKCTRHRVSYRTAYRHGEKTMYRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNVCSHWESYSVTVQESYPHPFDQIYYTSCTDILNWFKCTRHRVSYRTAYRHGEKTMYRR
90 100 110 120 130 140
100 110 120 130 140 150
pF1KA1 KSQCCPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSQCCPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTS
150 160 170 180 190 200
160 170 180 190 200 210
pF1KA1 RCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGEC
210 220 230 240 250 260
220 230 240 250 260 270
pF1KA1 RCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPE
270 280 290 300 310 320
280 290 300 310 320 330
pF1KA1 GRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGG
330 340 350 360 370 380
340 350 360 370 380 390
pF1KA1 KCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPG
390 400 410 420 430 440
400 410 420 430 440 450
pF1KA1 WSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGI
450 460 470 480 490 500
460 470 480 490 500 510
pF1KA1 NCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTL
510 520 530 540 550 560
520 530 540 550 560 570
pF1KA1 DGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDS
570 580 590 600 610 620
580 590 600 610 620 630
pF1KA1 VCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQ
630 640 650 660 670 680
640 650 660 670 680 690
pF1KA1 CVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQC
690 700 710 720 730 740
700 710 720 730 740 750
pF1KA1 YPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGF
750 760 770 780 790 800
760 770 780 790 800 810
pF1KA1 YGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTC
810 820 830 840 850 860
820 830 840 850 860 870
pF1KA1 DHITGTCYCSPGWKGARCDQAGVIIVGNLNSLSRTSTALPADSYQIGAIAGIIILVLVVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHITGTCYCSPGWKGARCDQAGVIIVGNLNSLSRTSTALPADSYQIGAIAGIIILVLVVL
870 880 890 900 910 920
880 890 900 910 920 930
pF1KA1 FLLALFIIYRHKQKGKESSMPAVTYTPAMRVVNADYTISGTLPHSNGGNANSHYFTNPSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLLALFIIYRHKQKGKESSMPAVTYTPAMRVVNADYTISGTLPHSNGGNANSHYFTNPSY
930 940 950 960 970 980
940 950 960 970 980 990
pF1KA1 HTLTQCATSPHVNNRDRMTVTKSKNNQLFVNLKNVNPGKRGPVGDCTGTLPADWKHGGYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTLTQCATSPHVNNRDRMTVTKSKNNQLFVNLKNVNPGKRGPVGDCTGTLPADWKHGGYL
990 1000 1010 1020 1030 1040
1000 1010 1020 1030 1040 1050
pF1KA1 NELGAFGLDRSYMGKSLKDLGKNSEYNSSNCSLSSSENPYATIKDPPVLIPKSSECGYVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NELGAFGLDRSYMGKSLKDLGKNSEYNSSNCSLSSSENPYATIKDPPVLIPKSSECGYVE
1050 1060 1070 1080 1090 1100
1060 1070 1080 1090 1100 1110
pF1KA1 MKSPARRDSPYAEINNSTSANRNVYEVEPTVSVVQGVFSNNGRLSQDPYDLPKNSHIPCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKSPARRDSPYAEINNSTSANRNVYEVEPTVSVVQGVFSNNGRLSQDPYDLPKNSHIPCH
1110 1120 1130 1140 1150 1160
1120 1130 1140
pF1KA1 YDLLPVRDSSSSPKQEDSGGSSSNSSSSSE
::::::::::::::::::::::::::::::
XP_016 YDLLPVRDSSSSPKQEDSGGSSSNSSSSSE
1170 1180 1190
>>XP_016865477 (OMIM: 612453,614399) PREDICTED: multiple (760 aa)
initn: 5752 init1: 5752 opt: 5752 Z-score: 3137.1 bits: 591.8 E(85289): 5.3e-168
Smith-Waterman score: 5752; 100.0% identity (100.0% similar) in 760 aa overlap (381-1140:1-760)
360 370 380 390 400 410
pF1KA1 EARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQ
::::::::::::::::::::::::::::::
XP_016 MSGECACKPGWSGLYCNETCSPGFYGEACQ
10 20 30
420 430 440 450 460 470
pF1KA1 QICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGS
40 50 60 70 80 90
480 490 500 510 520 530
pF1KA1 CTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQ
100 110 120 130 140 150
540 550 560 570 580 590
pF1KA1 DGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNG
160 170 180 190 200 210
600 610 620 630 640 650
pF1KA1 ASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPG
220 230 240 250 260 270
660 670 680 690 700 710
pF1KA1 FTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGP
280 290 300 310 320 330
720 730 740 750 760 770
pF1KA1 NCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHI
340 350 360 370 380 390
780 790 800 810 820 830
pF1KA1 SGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQ
400 410 420 430 440 450
840 850 860 870 880 890
pF1KA1 AGVIIVGNLNSLSRTSTALPADSYQIGAIAGIIILVLVVLFLLALFIIYRHKQKGKESSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGVIIVGNLNSLSRTSTALPADSYQIGAIAGIIILVLVVLFLLALFIIYRHKQKGKESSM
460 470 480 490 500 510
900 910 920 930 940 950
pF1KA1 PAVTYTPAMRVVNADYTISGTLPHSNGGNANSHYFTNPSYHTLTQCATSPHVNNRDRMTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAVTYTPAMRVVNADYTISGTLPHSNGGNANSHYFTNPSYHTLTQCATSPHVNNRDRMTV
520 530 540 550 560 570
960 970 980 990 1000 1010
pF1KA1 TKSKNNQLFVNLKNVNPGKRGPVGDCTGTLPADWKHGGYLNELGAFGLDRSYMGKSLKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKSKNNQLFVNLKNVNPGKRGPVGDCTGTLPADWKHGGYLNELGAFGLDRSYMGKSLKDL
580 590 600 610 620 630
1020 1030 1040 1050 1060 1070
pF1KA1 GKNSEYNSSNCSLSSSENPYATIKDPPVLIPKSSECGYVEMKSPARRDSPYAEINNSTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKNSEYNSSNCSLSSSENPYATIKDPPVLIPKSSECGYVEMKSPARRDSPYAEINNSTSA
640 650 660 670 680 690
1080 1090 1100 1110 1120 1130
pF1KA1 NRNVYEVEPTVSVVQGVFSNNGRLSQDPYDLPKNSHIPCHYDLLPVRDSSSSPKQEDSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRNVYEVEPTVSVVQGVFSNNGRLSQDPYDLPKNSHIPCHYDLLPVRDSSSSPKQEDSGG
700 710 720 730 740 750
1140
pF1KA1 SSSNSSSSSE
::::::::::
XP_016 SSSNSSSSSE
760
>>XP_016878160 (OMIM: 612454) PREDICTED: multiple epider (1092 aa)
initn: 5084 init1: 5084 opt: 5273 Z-score: 2876.5 bits: 544.1 E(85289): 1.7e-153
Smith-Waterman score: 5527; 60.8% identity (81.6% similar) in 1099 aa overlap (1-1077:1-1087)
10 20 30 40 50 60
pF1KA1 MVISLNSCLSFICLLLCHWIGTASPLNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSC
::.::.. ..: .. .. :: ::::::::::::.::::::: ::::::::: :
XP_016 MVLSLTGLIAF------SFLQATLALNPEDPNVCSHWESYAVTVQESYAHPFDQIYYTRC
10 20 30 40 50
70 80 90 100 110 120
pF1KA1 TDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIA
:::::::::::::.::.::::.: .:::::.::::::.::::..:.: :...::::::..
XP_016 TDILNWFKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCVS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KA1 PNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCED
:.::.::::::: .:::.::.:::::::..::::.:::::::::::: :::::::::::.
XP_016 PDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEE
120 130 140 150 160 170
190 200 210 220 230 240
pF1KA1 RCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPC
: ::.:. :. :::..::.:: .::: : :::::..::.:::::.:: .:: ::::
XP_016 LCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPC
180 190 200 210 220 230
250 260 270 280 290 300
pF1KA1 QNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSP
::::.:::.::::.:: :: :.::.:::: : ::.::::.: ::.:: :: .::::::.
XP_016 QNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTA
240 250 260 270 280 290
310 320 330 340 350 360
pF1KA1 GYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLY
:: :.:::.::: :..: :.. :.: :::.: ..::: :: :. : ::. :::::::.
XP_016 GYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLH
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA1 GIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGAD
: : ::: .:: ::::..: :.:.::::: .:::.: :.::..:: :.::::::
XP_016 GPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGAD
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA1 CDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGV
: :.:: ::::::: : :.. : :::: :::: :.:.: ..::::::::::: ::.:.
XP_016 CHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGL
420 430 440 450 460 470
490 500 510 520 530 540
pF1KA1 DCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAE
::.. :::::::..:: .: : ::.::. .::.:.:.::: :. ::::: :::.::::.:
XP_016 DCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSE
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA1 RCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGIC
.::::::::: :.:::: :: ::.:..:::.: ::::::::. : :.::.::::.:: :
XP_016 HCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSC
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA1 ECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVC
:::::::: ::::: :::::: :.: :: ::::: :::::.:.:.:::::.:::::.::
XP_016 ECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVC
600 610 620 630 640 650
670 680 690 700 710 720
pF1KA1 PSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHN
.: ::..:: .:.:.:::::.::: ::::.:::::.:::: :::. ::: :.:.:.:::
XP_016 AGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHN
660 670 680 690 700 710
730 740 750 760 770 780
pF1KA1 GAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGF
:: ::: :: :.::::::::.:::::: .:.::::. .:::::::.::::::.:::::::
XP_016 GASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGF
720 730 740 750 760 770
790 800 810 820 830 840
pF1KA1 MGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLN
:.::::.: ::.::::.:.:.:.:::::::.:::::::::.:: :::::.... .::
XP_016 TGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCDQAALMME-ELN
780 790 800 810 820 830
850 860 870 880 890
pF1KA1 SLSRTSTALPADSYQIGAIAGIIILVLVVLFLLALFIIYRHKQKGKESSM-PAVTYTPAM
.. : :: :. ...::..::..:..... ::.:: .:..:: : .. : :.:::::
XP_016 PYTKISPALGAERHSVGAVTGIMLLLFLIVVLLGLFAWHRRRQKEKGRDLAPRVSYTPAM
840 850 860 870 880 890
900 910 920 930 940 950
pF1KA1 RVVNADYTISGTLPHSNGGNANSHYFTNPSYHTLTQCA--TSPHVNNRDRMTVTKSKNNQ
:....::..: : .:. ...: :.: :::.:. :. .. .... :: . :: .:..
XP_016 RMTSTDYSLSD-LSQSS---SHAHCFSNSSYHALA-CGGPATSQASTLDRNSPTKLSNKS
900 910 920 930 940
960 970 980 990 1000
pF1KA1 LFVNLKNVNPGKRGPVGDC---TGTLPADWKHGGYLNEL------------GAFGLDR--
: . . .: . : : ..: : . . :: :: :.::
XP_016 LDRDTAGWTPYSYVNVLDSHFQISALEARYPPEDFYIELRHLSRPAEPHSPGACGMDRRQ
950 960 970 980 990 1000
1010 1020 1030 1040 1050
pF1KA1 -SY-MGKSLKDLGKNSEYNSSNCSLSSSENPYATIKDPPVLIPKSSECGYVEMKSPARRD
.: : :..:: :.: .::.:::.:::::::::::::.: : : .:::::::..
XP_016 NTYIMDKGFKDYMKESVCSSSTCSLNSSENPYATIKDPPILTCKLPESSYVEMKSPVHMG
1010 1020 1030 1040 1050 1060
1060 1070 1080 1090 1100 1110
pF1KA1 SPYAEINNSTSANRNVYEVEPTVSVVQGVFSNNGRLSQDPYDLPKNSHIPCHYDLLPVRD
:::... . ...:.:.:::
XP_016 SPYTDVPSLSTSNKNIYEVGRCLK
1070 1080 1090
>>XP_016878162 (OMIM: 612454) PREDICTED: multiple epider (1021 aa)
initn: 5084 init1: 5084 opt: 5271 Z-score: 2875.7 bits: 543.8 E(85289): 1.9e-153
Smith-Waterman score: 5276; 61.1% identity (81.7% similar) in 1031 aa overlap (1-1009:1-1019)
10 20 30 40 50 60
pF1KA1 MVISLNSCLSFICLLLCHWIGTASPLNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSC
::.::.. ..: .. .. :: ::::::::::::.::::::: ::::::::: :
XP_016 MVLSLTGLIAF------SFLQATLALNPEDPNVCSHWESYAVTVQESYAHPFDQIYYTRC
10 20 30 40 50
70 80 90 100 110 120
pF1KA1 TDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIA
:::::::::::::.::.::::.: .:::::.::::::.::::..:.: :...::::::..
XP_016 TDILNWFKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCVS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KA1 PNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCED
:.::.::::::: .:::.::.:::::::..::::.:::::::::::: :::::::::::.
XP_016 PDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEE
120 130 140 150 160 170
190 200 210 220 230 240
pF1KA1 RCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPC
: ::.:. :. :::..::.:: .::: : :::::..::.:::::.:: .:: ::::
XP_016 LCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPC
180 190 200 210 220 230
250 260 270 280 290 300
pF1KA1 QNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSP
::::.:::.::::.:: :: :.::.:::: : ::.::::.: ::.:: :: .::::::.
XP_016 QNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTA
240 250 260 270 280 290
310 320 330 340 350 360
pF1KA1 GYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLY
:: :.:::.::: :..: :.. :.: :::.: ..::: :: :. : ::. :::::::.
XP_016 GYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLH
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA1 GIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGAD
: : ::: .:: ::::..: :.:.::::: .:::.: :.::..:: :.::::::
XP_016 GPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGAD
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA1 CDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGV
: :.:: ::::::: : :.. : :::: :::: :.:.: ..::::::::::: ::.:.
XP_016 CHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGL
420 430 440 450 460 470
490 500 510 520 530 540
pF1KA1 DCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAE
::.. :::::::..:: .: : ::.::. .::.:.:.::: :. ::::: :::.::::.:
XP_016 DCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSE
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA1 RCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGIC
.::::::::: :.:::: :: ::.:..:::.: ::::::::. : :.::.::::.:: :
XP_016 HCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSC
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA1 ECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVC
:::::::: ::::: :::::: :.: :: ::::: :::::.:.:.:::::.:::::.::
XP_016 ECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVC
600 610 620 630 640 650
670 680 690 700 710 720
pF1KA1 PSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHN
.: ::..:: .:.:.:::::.::: ::::.:::::.:::: :::. ::: :.:.:.:::
XP_016 AGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHN
660 670 680 690 700 710
730 740 750 760 770 780
pF1KA1 GAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGF
:: ::: :: :.::::::::.:::::: .:.::::. .:::::::.::::::.:::::::
XP_016 GASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGF
720 730 740 750 760 770
790 800 810 820 830 840
pF1KA1 MGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLN
:.::::.: ::.::::.:.:.:.:::::::.:::::::::.:: :::::. ... .::
XP_016 TGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCDQAA-LMMEELN
780 790 800 810 820 830
850 860 870 880 890
pF1KA1 SLSRTSTALPADSYQIGAIAGIIILVLVVLFLLALFIIYRHKQKGKESSM-PAVTYTPAM
.. : :: :. ...::..::..:..... ::.:: .:..:: : .. : :.:::::
XP_016 PYTKISPALGAERHSVGAVTGIMLLLFLIVVLLGLFAWHRRRQKEKGRDLAPRVSYTPAM
840 850 860 870 880 890
900 910 920 930 940 950
pF1KA1 RVVNADYTISGTLPHSNGGNANSHYFTNPSYHTLTQCA--TSPHVNNRDRMTVTKSKNNQ
:....::..: : .:. ...: :.: :::.:. :. .. .... :: . :: .:..
XP_016 RMTSTDYSLSD-LSQSS---SHAHCFSNSSYHALA-CGGPATSQASTLDRNSPTKLSNKS
900 910 920 930 940
960 970 980 990 1000
pF1KA1 LFVNLKNVNPGKRGPVGDC---TGTLPADWKHGGYLNEL------------GAFGLDR--
: . . .: . : : ..: : . . :: :: :.::
XP_016 LDRDTAGWTPYSYVNVLDSHFQISALEARYPPEDFYIELRHLSRPAEPHSPGACGMDRRQ
950 960 970 980 990 1000
1010 1020 1030 1040 1050
pF1KA1 -SY-MGKSLKDLGKNSEYNSSNCSLSSSENPYATIKDPPVLIPKSSECGYVEMKSPARRD
.: : :..::
XP_016 NTYIMDKGFKDAN
1010 1020
>>NP_115821 (OMIM: 612454) multiple epidermal growth fac (1044 aa)
initn: 5532 init1: 5092 opt: 5224 Z-score: 2850.2 bits: 539.1 E(85289): 5.1e-152
Smith-Waterman score: 5531; 59.8% identity (79.0% similar) in 1128 aa overlap (1-1126:1-1041)
10 20 30 40 50 60
pF1KA1 MVISLNSCLSFICLLLCHWIGTASPLNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSC
::.::.. ..: .. .. :: ::::::::::::.::::::: ::::::::: :
NP_115 MVLSLTGLIAF------SFLQATLALNPEDPNVCSHWESYAVTVQESYAHPFDQIYYTRC
10 20 30 40 50
70 80 90 100 110 120
pF1KA1 TDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIA
:::::::::::::.::.::::.: .:::::.::::::.::::..:.: :...::::::..
NP_115 TDILNWFKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCVS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KA1 PNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCED
:.::.::::::: .:::.::.:::::::..::::.:::::::::::: :::::::::::.
NP_115 PDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEE
120 130 140 150 160 170
190 200 210 220 230 240
pF1KA1 RCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPC
: ::.:. :. :::..::.:: .::: : :::::..::.:::::.:: .:: ::::
NP_115 LCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPC
180 190 200 210 220 230
250 260 270 280 290 300
pF1KA1 QNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSP
::::.:::.::::.:: :: :.::.:::: : ::.::::.: ::.:: :: .::::::.
NP_115 QNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTA
240 250 260 270 280 290
310 320 330 340 350 360
pF1KA1 GYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLY
:: :.:::.::: :..: :.. :.: :::.: ..::: :: :. : ::. :::::::.
NP_115 GYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLH
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA1 GIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGAD
: : ::: .:: ::::..: :.:.::::: .:::.: :.::..:: :.::::::
NP_115 GPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGAD
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA1 CDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGV
: :.:: ::::::: : :.. : :::: :::: :.:.: ..::::::::::: ::.:.
NP_115 CHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGL
420 430 440 450 460 470
490 500 510 520 530 540
pF1KA1 DCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAE
::.. :::::::..:: .: : ::.::. .::.:.:.::: :. ::::: :::.::::.:
NP_115 DCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSE
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA1 RCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGIC
.::::::::: :.:::: :: ::.:..:::.: ::::::::. : :.::.::::.:: :
NP_115 HCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSC
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA1 ECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVC
:::::::: ::::: :::::: :.: :: ::::: :::::.:.:.:::::.:::::.::
NP_115 ECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVC
600 610 620 630 640 650
670 680 690 700 710 720
pF1KA1 PSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHN
.: ::..:: .:.:.:::::.::: ::::.:::::.:::: :::. ::: :.:.:.:::
NP_115 AGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHN
660 670 680 690 700 710
730 740 750 760 770 780
pF1KA1 GAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGF
:: ::: :: :.::::::::.:::::: .:.::::. .:::::::.::::::.:::::::
NP_115 GASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGF
720 730 740 750 760 770
790 800 810 820 830 840
pF1KA1 MGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLN
:.::::.: ::.::::.:.:.:.:::::::.:::::::::.:: :::::.... .::
NP_115 TGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCDQAALMME-ELN
780 790 800 810 820 830
850 860 870 880 890
pF1KA1 SLSRTSTALPADSYQIGAIAGIIILVLVVLFLLALFIIYRHKQKGKESSM-PAVTYTPAM
.. : :: :. ...::..::..:..... ::.:: .:..:: : .. : :.:::::
NP_115 PYTKISPALGAERHSVGAVTGIMLLLFLIVVLLGLFAWHRRRQKEKGRDLAPRVSYTPAM
840 850 860 870 880 890
900 910 920 930 940 950
pF1KA1 RVVNADYTISGTLPHSNGGNANSHYFTNPSYHTLTQCATSPHVNNRDRMTVTKSKNNQLF
:....::..::. :. ::
NP_115 RMTSTDYSLSGA------------------------CGM-------DR------------
900 910
960 970 980 990 1000 1010
pF1KA1 VNLKNVNPGKRGPVGDCTGTLPADWKHGGYLNELGAFGLDRSYMGKSLKDLGKNSEYNSS
... :. : :..:: :.: .::
NP_115 -------------------------RQNTYI------------MDKGFKDYMKESVCSSS
920 930
1020 1030 1040 1050 1060 1070
pF1KA1 NCSLSSSENPYATIKDPPVLIPKSSECGYVEMKSPARRDSPYAEINNSTSANRNVYEVEP
.:::.:::::::::::::.: : : .:::::::.. :::... . ...:.:.:::::
NP_115 TCSLNSSENPYATIKDPPILTCKLPESSYVEMKSPVHMGSPYTDVPSLSTSNKNIYEVEP
940 950 960 970 980 990
1080 1090 1100 1110 1120 1130
pF1KA1 TVSVVQGVFSNNGRLSQDPYDLPKNSHIPCHYDLLPVRDS-SSSPKQEDSGGSSSNSSSS
:::::: ..:. :. ::::.::::: ::::::::.: ...:.:.
NP_115 TVSVVQEGCGHNSSYIQNAYDLPRNSHIPGHYDLLPVRQSPANGPSQDKQS
1000 1010 1020 1030 1040
1140
pF1KA1 SE
>>XP_016878161 (OMIM: 612454) PREDICTED: multiple epider (1044 aa)
initn: 5532 init1: 5092 opt: 5224 Z-score: 2850.2 bits: 539.1 E(85289): 5.1e-152
Smith-Waterman score: 5531; 59.8% identity (79.0% similar) in 1128 aa overlap (1-1126:1-1041)
10 20 30 40 50 60
pF1KA1 MVISLNSCLSFICLLLCHWIGTASPLNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSC
::.::.. ..: .. .. :: ::::::::::::.::::::: ::::::::: :
XP_016 MVLSLTGLIAF------SFLQATLALNPEDPNVCSHWESYAVTVQESYAHPFDQIYYTRC
10 20 30 40 50
70 80 90 100 110 120
pF1KA1 TDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIA
:::::::::::::.::.::::.: .:::::.::::::.::::..:.: :...::::::..
XP_016 TDILNWFKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCVS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KA1 PNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCED
:.::.::::::: .:::.::.:::::::..::::.:::::::::::: :::::::::::.
XP_016 PDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEE
120 130 140 150 160 170
190 200 210 220 230 240
pF1KA1 RCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPC
: ::.:. :. :::..::.:: .::: : :::::..::.:::::.:: .:: ::::
XP_016 LCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPC
180 190 200 210 220 230
250 260 270 280 290 300
pF1KA1 QNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSP
::::.:::.::::.:: :: :.::.:::: : ::.::::.: ::.:: :: .::::::.
XP_016 QNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTA
240 250 260 270 280 290
310 320 330 340 350 360
pF1KA1 GYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLY
:: :.:::.::: :..: :.. :.: :::.: ..::: :: :. : ::. :::::::.
XP_016 GYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLH
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA1 GIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGAD
: : ::: .:: ::::..: :.:.::::: .:::.: :.::..:: :.::::::
XP_016 GPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGAD
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA1 CDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGV
: :.:: ::::::: : :.. : :::: :::: :.:.: ..::::::::::: ::.:.
XP_016 CHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGL
420 430 440 450 460 470
490 500 510 520 530 540
pF1KA1 DCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAE
::.. :::::::..:: .: : ::.::. .::.:.:.::: :. ::::: :::.::::.:
XP_016 DCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSE
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA1 RCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGIC
.::::::::: :.:::: :: ::.:..:::.: ::::::::. : :.::.::::.:: :
XP_016 HCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSC
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA1 ECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVC
:::::::: ::::: :::::: :.: :: ::::: :::::.:.:.:::::.:::::.::
XP_016 ECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVC
600 610 620 630 640 650
670 680 690 700 710 720
pF1KA1 PSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHN
.: ::..:: .:.:.:::::.::: ::::.:::::.:::: :::. ::: :.:.:.:::
XP_016 AGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHN
660 670 680 690 700 710
730 740 750 760 770 780
pF1KA1 GAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGF
:: ::: :: :.::::::::.:::::: .:.::::. .:::::::.::::::.:::::::
XP_016 GASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGF
720 730 740 750 760 770
790 800 810 820 830 840
pF1KA1 MGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLN
:.::::.: ::.::::.:.:.:.:::::::.:::::::::.:: :::::.... .::
XP_016 TGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCDQAALMME-ELN
780 790 800 810 820 830
850 860 870 880 890
pF1KA1 SLSRTSTALPADSYQIGAIAGIIILVLVVLFLLALFIIYRHKQKGKESSM-PAVTYTPAM
.. : :: :. ...::..::..:..... ::.:: .:..:: : .. : :.:::::
XP_016 PYTKISPALGAERHSVGAVTGIMLLLFLIVVLLGLFAWHRRRQKEKGRDLAPRVSYTPAM
840 850 860 870 880 890
900 910 920 930 940 950
pF1KA1 RVVNADYTISGTLPHSNGGNANSHYFTNPSYHTLTQCATSPHVNNRDRMTVTKSKNNQLF
:....::..::. :. ::
XP_016 RMTSTDYSLSGA------------------------CGM-------DR------------
900 910
960 970 980 990 1000 1010
pF1KA1 VNLKNVNPGKRGPVGDCTGTLPADWKHGGYLNELGAFGLDRSYMGKSLKDLGKNSEYNSS
... :. : :..:: :.: .::
XP_016 -------------------------RQNTYI------------MDKGFKDYMKESVCSSS
920 930
1020 1030 1040 1050 1060 1070
pF1KA1 NCSLSSSENPYATIKDPPVLIPKSSECGYVEMKSPARRDSPYAEINNSTSANRNVYEVEP
.:::.:::::::::::::.: : : .:::::::.. :::... . ...:.:.:::::
XP_016 TCSLNSSENPYATIKDPPILTCKLPESSYVEMKSPVHMGSPYTDVPSLSTSNKNIYEVEP
940 950 960 970 980 990
1080 1090 1100 1110 1120 1130
pF1KA1 TVSVVQGVFSNNGRLSQDPYDLPKNSHIPCHYDLLPVRDS-SSSPKQEDSGGSSSNSSSS
:::::: ..:. :. ::::.::::: ::::::::.: ...:.:.
XP_016 TVSVVQEGCGHNSSYIQNAYDLPRNSHIPGHYDLLPVRQSPANGPSQDKQS
1000 1010 1020 1030 1040
1140
pF1KA1 SE
>>NP_001295048 (OMIM: 612453,614399) multiple epidermal (567 aa)
initn: 5753 init1: 4568 opt: 4568 Z-score: 2497.6 bits: 473.0 E(85289): 2.2e-132
Smith-Waterman score: 4568; 99.8% identity (100.0% similar) in 566 aa overlap (1-566:1-566)
10 20 30 40 50 60
pF1KA1 MVISLNSCLSFICLLLCHWIGTASPLNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVISLNSCLSFICLLLCHWIGTASPLNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 TDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 PNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 RCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 QNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 GYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 GIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGAD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 CDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 DCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 RCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGIC
:::::::::::::::::::::::::.
NP_001 RCDCSHADGCHPTTGHCRCLPGWSGLF
550 560
1140 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 07:17:08 2016 done: Thu Nov 3 07:17:10 2016
Total Scan time: 12.180 Total Display time: 0.520
Function used was FASTA [36.3.4 Apr, 2011]