FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1788, 411 aa 1>>>pF1KA1788 411 - 411 aa - 411 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.1829+/-0.000433; mu= -6.2929+/- 0.027 mean_var=442.0762+/-88.639, 0's: 0 Z-trim(123.7): 145 B-trim: 191 in 1/58 Lambda= 0.060999 statistics sampled from 43756 (43939) to 43756 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.802), E-opt: 0.2 (0.515), width: 16 Scan time: 10.010 The best scores are: opt bits E(85289) NP_068745 (OMIM: 605420,609597,613451,615529) home ( 411) 2817 261.7 2.4e-69 XP_011537084 (OMIM: 601527,613456) PREDICTED: ALX ( 231) 782 82.3 1.3e-15 NP_008913 (OMIM: 601527,613456) ALX homeobox prote ( 326) 782 82.5 1.7e-15 NP_006483 (OMIM: 136760,606014) homeobox protein a ( 343) 721 77.2 7.2e-14 NP_001263380 (OMIM: 606701) dorsal root ganglia ho ( 263) 422 50.7 5e-06 NP_620689 (OMIM: 300004,300215,300382,300419,30835 ( 562) 418 50.7 1.1e-05 NP_878314 (OMIM: 142993,610092,610093) visual syst ( 361) 396 48.6 3e-05 NP_116142 (OMIM: 605726,610362,610381,613757) reti ( 184) 380 46.9 5.1e-05 NP_001306003 (OMIM: 605726,610362,610381,613757) r ( 230) 380 47.0 5.9e-05 XP_016883326 (OMIM: 122000,148300,605020,614195) P ( 280) 366 45.8 0.00016 NP_001243201 (OMIM: 122000,148300,605020,614195) v ( 301) 366 45.9 0.00017 NP_005020 (OMIM: 107250,602669,610623) pituitary h ( 302) 364 45.7 0.00019 NP_055403 (OMIM: 122000,148300,605020,614195) visu ( 365) 366 45.9 0.00019 NP_001191327 (OMIM: 137600,180500,180550,601542,60 ( 317) 359 45.3 0.00026 NP_001191326 (OMIM: 137600,180500,180550,601542,60 ( 317) 359 45.3 0.00026 NP_700475 (OMIM: 137600,180500,180550,601542,60422 ( 317) 359 45.3 0.00026 NP_003915 (OMIM: 209880,603851,613013) paired meso ( 314) 357 45.1 0.0003 NP_001290437 (OMIM: 612019) intestine-specific hom ( 245) 350 44.4 0.00038 NP_008833 (OMIM: 167420,202650) paired mesoderm ho ( 217) 345 43.9 0.00048 NP_038463 (OMIM: 601881,611038) retinal homeobox p ( 346) 349 44.4 0.00052 NP_000316 (OMIM: 137600,180500,180550,601542,60422 ( 324) 347 44.2 0.00056 XP_006711451 (OMIM: 167420,202650) PREDICTED: pair ( 198) 341 43.5 0.00057 NP_005160 (OMIM: 602078,602753) paired mesoderm ho ( 284) 344 43.9 0.00061 NP_073207 (OMIM: 167420,202650) paired mesoderm ho ( 245) 342 43.6 0.00062 NP_852126 (OMIM: 122880,148820,193500,268220,60659 ( 403) 347 44.3 0.00065 NP_852125 (OMIM: 122880,148820,193500,268220,60659 ( 407) 347 44.3 0.00065 XP_011530329 (OMIM: 137600,180500,180550,601542,60 ( 271) 342 43.7 0.00067 NP_700476 (OMIM: 137600,180500,180550,601542,60422 ( 271) 342 43.7 0.00067 NP_001191328 (OMIM: 137600,180500,180550,601542,60 ( 271) 342 43.7 0.00067 NP_002644 (OMIM: 119800,186550,602149) pituitary h ( 314) 343 43.8 0.0007 NP_852122 (OMIM: 122880,148820,193500,268220,60659 ( 479) 347 44.4 0.00073 NP_001120838 (OMIM: 122880,148820,193500,268220,60 ( 483) 347 44.4 0.00073 NP_852123 (OMIM: 122880,148820,193500,268220,60659 ( 484) 347 44.4 0.00073 NP_852124 (OMIM: 122880,148820,193500,268220,60659 ( 505) 347 44.4 0.00075 NP_039236 (OMIM: 167410,268220) paired box protein ( 518) 343 44.1 0.00098 NP_057391 (OMIM: 604675) paired mesoderm homeobox ( 253) 334 43.0 0.001 NP_001128726 (OMIM: 167410,268220) paired box prot ( 505) 339 43.7 0.0012 NP_002575 (OMIM: 167410,268220) paired box protein ( 520) 339 43.7 0.0013 NP_115485 (OMIM: 604529) homeobox protein orthoped ( 325) 332 42.9 0.0014 XP_016870292 (OMIM: 604675) PREDICTED: paired meso ( 193) 325 42.0 0.0015 NP_703149 (OMIM: 300154) homeobox protein ESX1 [Ho ( 406) 329 42.7 0.0019 NP_006875 (OMIM: 602504) short stature homeobox pr ( 331) 326 42.4 0.002 NP_003021 (OMIM: 602504) short stature homeobox pr ( 355) 326 42.4 0.0021 NP_001297088 (OMIM: 106210,120430,136520,148190,16 ( 401) 327 42.6 0.0022 NP_001245394 (OMIM: 106210,120430,136520,148190,16 ( 422) 325 42.4 0.0025 NP_000271 (OMIM: 106210,120430,136520,148190,16555 ( 422) 325 42.4 0.0025 NP_001245393 (OMIM: 106210,120430,136520,148190,16 ( 422) 325 42.4 0.0025 NP_001121084 (OMIM: 106210,120430,136520,148190,16 ( 422) 325 42.4 0.0025 NP_001245391 (OMIM: 106210,120430,136520,148190,16 ( 436) 325 42.4 0.0026 NP_001595 (OMIM: 106210,120430,136520,148190,16555 ( 436) 325 42.4 0.0026 >>NP_068745 (OMIM: 605420,609597,613451,615529) homeobox (411 aa) initn: 2817 init1: 2817 opt: 2817 Z-score: 1365.9 bits: 261.7 E(85289): 2.4e-69 Smith-Waterman score: 2817; 100.0% identity (100.0% similar) in 411 aa overlap (1-411:1-411) 10 20 30 40 50 60 pF1KA1 MNAETCVSYCESPAAAMDAYYSPVSQSREGSSPFRAFPGGDKFGTTFLSAAAKAQGFGDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 MNAETCVSYCESPAAAMDAYYSPVSQSREGSSPFRAFPGGDKFGTTFLSAAAKAQGFGDA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KSRARYGAGQQDLATPLESGAGARGSFNKFQPQPSTPQPQPPPQPQPQQQQPQPQPPAQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 KSRARYGAGQQDLATPLESGAGARGSFNKFQPQPSTPQPQPPPQPQPQQQQPQPQPPAQP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 HLYLQRGACKTPPDGSLKLQEGSSGHSAALQVPCYAKESSLGEPELPPDSDTVGMDSSYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 HLYLQRGACKTPPDGSLKLQEGSSGHSAALQVPCYAKESSLGEPELPPDSDTVGMDSSYL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 SVKEAGVKGPQDRASSDLPSPLEKADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 SVKEAGVKGPQDRASSDLPSPLEKADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 VYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 VYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 AQIQNPSWLGNNGAASPVPACVVPCDPVPACMSPHAHPPGSGASSVTDFLSVSGAGSHVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 AQIQNPSWLGNNGAASPVPACVVPCDPVPACMSPHAHPPGSGASSVTDFLSVSGAGSHVG 310 320 330 340 350 360 370 380 390 400 410 pF1KA1 QTHMGSLFGAASLSPGLNGYELNGEPDRKTSSIAALRMKAKEHSAAISWAT ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 QTHMGSLFGAASLSPGLNGYELNGEPDRKTSSIAALRMKAKEHSAAISWAT 370 380 390 400 410 >>XP_011537084 (OMIM: 601527,613456) PREDICTED: ALX home (231 aa) initn: 697 init1: 579 opt: 782 Z-score: 401.1 bits: 82.3 E(85289): 1.3e-15 Smith-Waterman score: 782; 52.5% identity (78.6% similar) in 238 aa overlap (175-410:1-230) 150 160 170 180 190 200 pF1KA1 GHSAALQVPCYAKESSLGEPELPPDSDTVGMDSSYLSVKEAGVKGPQDRASSDLPSPLEK ::. :.. . ::: :.. ..: .: XP_011 MDNCN-SLRMSPVKGMQEK--GELDELGDK 10 20 210 220 230 240 250 260 pF1KA1 ADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQN ::. ...::::.:::::: ::::::::::::::::::.:::::.::.:::::::::::: XP_011 CDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQN 30 40 50 60 70 80 270 280 290 300 310 320 pF1KA1 RRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYAQIQNPSWLGNNGAASPVPACVVP ::::::::::.::.::...::...:.. .: :...: :::: : :: ...: : .:..: XP_011 RRAKWRKRERYGQIQQAKSHFAATYDISVLPRTDSYPQIQNNLWAGNASGGSVVTSCMLP 90 100 110 120 130 140 330 340 350 360 370 380 pF1KA1 CDPVPACMSPHAHPPGSGASSVTDFLSVSGAGSHVGQTHMGSLFGAASLSPGLNGYELNG : . .::.:..: : . :: : : . .. ::: ....: . :. . ::. .. XP_011 RD-TSSCMTPYSHSPRTD-SSYTGFSNHQNQFSHVP---LNNFFTDSLLTGATNGHAFET 150 160 170 180 190 200 390 400 410 pF1KA1 EPD--RKTSSIAALRMKAKEHSAAISWAT .:. :..::::.::::::::.: :::: XP_011 KPEFERRSSSIAVLRMKAKEHTANISWAM 210 220 230 >>NP_008913 (OMIM: 601527,613456) ALX homeobox protein 1 (326 aa) initn: 697 init1: 579 opt: 782 Z-score: 399.3 bits: 82.5 E(85289): 1.7e-15 Smith-Waterman score: 782; 52.5% identity (78.6% similar) in 238 aa overlap (175-410:96-325) 150 160 170 180 190 200 pF1KA1 GHSAALQVPCYAKESSLGEPELPPDSDTVGMDSSYLSVKEAGVKGPQDRASSDLPSPLEK ::. :.. . ::: :.. ..: .: NP_008 ERTSPCQDSSVNYGITKVEGQPLHTELNRAMDNCN-SLRMSPVKGMQEK--GELDELGDK 70 80 90 100 110 120 210 220 230 240 250 260 pF1KA1 ADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQN ::. ...::::.:::::: ::::::::::::::::::.:::::.::.:::::::::::: NP_008 CDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQN 130 140 150 160 170 180 270 280 290 300 310 320 pF1KA1 RRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYAQIQNPSWLGNNGAASPVPACVVP ::::::::::.::.::...::...:.. .: :...: :::: : :: ...: : .:..: NP_008 RRAKWRKRERYGQIQQAKSHFAATYDISVLPRTDSYPQIQNNLWAGNASGGSVVTSCMLP 190 200 210 220 230 240 330 340 350 360 370 380 pF1KA1 CDPVPACMSPHAHPPGSGASSVTDFLSVSGAGSHVGQTHMGSLFGAASLSPGLNGYELNG : . .::.:..: : . :: : : . .. ::: ....: . :. . ::. .. NP_008 RD-TSSCMTPYSHSPRTD-SSYTGFSNHQNQFSHVP---LNNFFTDSLLTGATNGHAFET 250 260 270 280 290 390 400 410 pF1KA1 EPD--RKTSSIAALRMKAKEHSAAISWAT .:. :..::::.::::::::.: :::: NP_008 KPEFERRSSSIAVLRMKAKEHTANISWAM 300 310 320 >>NP_006483 (OMIM: 136760,606014) homeobox protein arist (343 aa) initn: 681 init1: 583 opt: 721 Z-score: 370.0 bits: 77.2 E(85289): 7.2e-14 Smith-Waterman score: 731; 41.1% identity (63.1% similar) in 360 aa overlap (76-411:8-343) 50 60 70 80 90 100 pF1KA1 TFLSAAAKAQGFGDAKSRARYGAGQQDLATPLESGAGARGSFNKFQPQPSTPQPQPPPQP :.. : : : . .: : :: : NP_006 MDPEHCAPFRVGP-APGPYVASGDEP--PGPQGTPAA 10 20 30 110 120 130 140 150 pF1KA1 QPQQQQPQPQPPAQPHLYLQRGAC----------KTPPDGSLK-LQEG---SSGHSAALQ :. . : :: :.: . :: :: :. : : ..:: . NP_006 APHLH---PAPPRGPRL-TRFPACGPLEPYLPEPAKPPAKYLQDLGPGPALNGGH--FYE 40 50 60 70 80 160 170 180 190 200 pF1KA1 VPCYAKESS---LGEPELPPDSDTVGMDS-SYLSVKEAGVKGPQDRASSDLP-SPL--EK : :.:.. . :.:: : :. : :. : :: :: :: :: .. NP_006 GPAEAEEKTSKAASFPQLPLDCRGGPRDGPSNLQ----GSPGPC-LASLHLPLSPGLPDS 90 100 110 120 130 140 210 220 230 240 250 260 pF1KA1 ADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQN . .::.:::::::::...::::::::::::::::::::::::.::::::::::::::: NP_006 MELAKNKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQN 150 160 170 180 190 200 270 280 290 300 310 320 pF1KA1 RRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYAQIQNPSWLGNNGAASPVPACVVP ::::::::::.:..:. :. :..::.. .: :.... :.:: : .. :..:: :.: NP_006 RRAKWRKRERYGKIQEGRNPFTAAYDISVLPRTDSHPQLQNSLW-ASPGSGSPGGPCLVS 210 220 230 240 250 260 330 340 350 360 370 380 pF1KA1 CDPVPA-CMSPHAHPPGSGASSVTDFLSVSGAGSHVGQTHMGSLFGAASLSPGLNG--YE . .:. ::::..:: :: :. :..: . .. .: : ... .. : :.: .: NP_006 PEGIPSPCMSPYSHPHGS----VAGFMGVPAPSA----AHPG-IYSIHGFPPTLGGHSFE 270 280 290 300 310 390 400 410 pF1KA1 LNGEPDRKTSSIAALRMKAKEHSAAISWAT ... : :. :...::.: :: . ..:.: NP_006 PSSDGDYKSPSLVSLRVKPKEPPGLLNWTT 320 330 340 >>NP_001263380 (OMIM: 606701) dorsal root ganglia homeob (263 aa) initn: 430 init1: 330 opt: 422 Z-score: 229.2 bits: 50.7 E(85289): 5e-06 Smith-Waterman score: 422; 42.2% identity (62.3% similar) in 199 aa overlap (213-407:32-220) 190 200 210 220 230 240 pF1KA1 KEAGVKGPQDRASSDLPSPLEKADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVY :.:::::::: ::: :: :: .::::::. NP_001 FYFHCPPQLEGTATFGNHSSGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVF 10 20 30 40 50 60 250 260 270 280 290 300 pF1KA1 AREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYAQ .::.:::. .::::::::::::::::::: :: .. :. .. : : .: : NP_001 TREELAMKINLTEARVQVWFQNRRAKWRKTERGASDQEPGAKEPMAEVTPPPVRNINSPP 70 80 90 100 110 120 310 320 330 340 350 pF1KA1 IQNPSWLGNNG--AASPVPACVVPCDPV-PACMSPHAHPPGSGASSVTDFLSVSGAGSHV . . ... : . . : : : :.:. ::. ...: . : ::: NP_001 PGDQARSKKEALEAQQSLGRTVGPAGPFFPSCL------PGTLLNTAT----YAQALSHV 130 140 150 160 170 360 370 380 390 400 410 pF1KA1 GQTHMGSLFGAASLSP-GLNGYELNGEPDRKTSSIAALRMKAKEHSAAISWAT .. . : : . .: ::. : . .:.:.:.:::::.::: :. NP_001 ASLKGGPLCSCCVPDPMGLSFLPTYGCQSNRTASVATLRMKAREHSEAVLQSANLLPSTS 180 190 200 210 220 230 NP_001 SSPGPVAKPAPPDGSQEKTSPTKEQSEAEKSV 240 250 260 >>NP_620689 (OMIM: 300004,300215,300382,300419,308350,30 (562 aa) initn: 537 init1: 366 opt: 418 Z-score: 223.3 bits: 50.7 E(85289): 1.1e-05 Smith-Waterman score: 485; 41.6% identity (61.4% similar) in 267 aa overlap (173-408:282-547) 150 160 170 180 190 200 pF1KA1 SSGHSAALQVPCYAKESSLGEPELPPDSDTVGMDSSYLSVKEAGVKGPQDRASSD-LPSP :. ... :: :: . :.: ..: : NP_620 LEDDARALLKEPRRCPVAATGAVAAAAAAAVATEGGELSPKEELLLHPEDAEGKDGEDSV 260 270 280 290 300 310 210 220 230 240 250 pF1KA1 LEKADSESNKG----KKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEAR .: :.:..: :.:: :::::::::::::..:::::::::..::.:::: :::::: NP_620 CLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEAR 320 330 340 350 360 370 260 270 280 290 300 310 pF1KA1 VQVWFQNRRAKWRKRERFG-QMQQVRTHF----STAYELPLLTRAENYAQIQNPSWLGNN ::::::::::::::::. : : . : :... : : . ..:. . NP_620 VQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDASPFPP-HHPALDSAW 380 390 400 410 420 430 320 330 340 350 360 pF1KA1 GAASPVPACVVPCDPVP---ACMSPHAHPPGS----GASSVTDFLSVSGAGSHVGQTH-- ::. . : . : : : : . : . : : ::. .: : ... .: NP_620 TAAAAAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAP 440 450 460 470 480 490 370 380 390 400 410 pF1KA1 MGSLFGAASL----SPGLNGYELNG---EP-----DRKTSSIAALRMKAKEHSAAISWAT . : ::.: .:...: .: .: ::..:::::::.:::::.: .. NP_620 LTSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEHAAQLTQLN 500 510 520 530 540 550 NP_620 ILPGTSTGKEVC 560 >>NP_878314 (OMIM: 142993,610092,610093) visual system h (361 aa) initn: 452 init1: 355 opt: 396 Z-score: 215.2 bits: 48.6 E(85289): 3e-05 Smith-Waterman score: 402; 38.2% identity (61.4% similar) in 220 aa overlap (58-274:6-208) 30 40 50 60 70 80 pF1KA1 REGSSPFRAFPGGDKFGTTFLSAAAKAQGFGDAKSRARYGAGQQDLATPLESGAGARGSF :.: :. . .. .: .:: :: . NP_878 MTGKAGEALSKPK----SETVAKSTSGGAPARCT- 10 20 30 90 100 110 120 130 140 pF1KA1 NKFQPQPSTPQPQPPPQPQPQQQQPQPQPPAQPHLYLQRGACKTPPDGSLKLQEGSSGHS : : . ::. .:. : :: :.. . :.. : : .: NP_878 -GFGIQEILGLNKEPPSSHPRAALDGLAPG---HLLAARSVLSPAGVGGMGLL-GPGGLP 40 50 60 70 80 150 160 170 180 190 200 pF1KA1 AALQVPCYAKESSLGEPE---LPPDSDTVGMDSSYLSVKEAGVKGPQDRASSDLPSPLEK . : . . :..:. : : .: :. :...... . .: .::: .. NP_878 GFYTQPTFLE--VLSDPQSVHLQP----LGRASGPLDTSQTASSDSEDVSSSDRKMS-KS 90 100 110 120 130 210 220 230 240 250 260 pF1KA1 ADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQN : ....: ::::.:: :::::::::::.:...:::::::::.:::.:.: : :.:::::: NP_878 ALNQTKKRKKRRHRTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQN 140 150 160 170 180 190 270 280 290 300 310 320 pF1KA1 RRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYAQIQNPSWLGNNGAASPVPACVVP :::::::::. NP_878 RRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLPESILKSAKDGIMDSCAPWLLGMHKK 200 210 220 230 240 250 >>NP_116142 (OMIM: 605726,610362,610381,613757) retina a (184 aa) initn: 361 init1: 327 opt: 380 Z-score: 211.2 bits: 46.9 E(85289): 5.1e-05 Smith-Waterman score: 380; 46.7% identity (70.4% similar) in 135 aa overlap (208-339:21-153) 180 190 200 210 220 230 pF1KA1 SYLSVKEAGVKGPQDRASSDLPSPLEKADSESNKGKKRRNRTTFTSYQLEELEKVFQKTH :. : :.::::::::.:::..::..:. .: NP_116 MFLSPGEGPATEGGGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASH 10 20 30 40 50 240 250 260 270 280 290 pF1KA1 YPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERF--GQMQQVRTHFSTAYELPLLT :::::.::.:: .. : :.::::::::::::::..::. :. . .. : ::. . NP_116 YPDVYSREELAAKVHLPEVRVQVWFQNRRAKWRRQERLESGSGAVAAPRLPEAPALPF-A 60 70 80 90 100 300 310 320 330 340 350 pF1KA1 RAENYAQIQNPSWLGNNGAASP-VPACVVPCDPVPACMSPHAHPPGSGASSVTDFLSVSG : .. .: ::: . : : .: . : . : ..::: : NP_116 RPPAMSLPLEP-WLGPGPPAVPGLPRLLGPGPGLQASFGPHAFAPTFADGFALEEASLRL 110 120 130 140 150 160 360 370 380 390 400 410 pF1KA1 AGSHVGQTHMGSLFGAASLSPGLNGYELNGEPDRKTSSIAALRMKAKEHSAAISWAT NP_116 LAKEHAQALDRAWPPA 170 180 >>NP_001306003 (OMIM: 605726,610362,610381,613757) retin (230 aa) initn: 383 init1: 327 opt: 380 Z-score: 210.0 bits: 47.0 E(85289): 5.9e-05 Smith-Waterman score: 397; 39.8% identity (63.3% similar) in 196 aa overlap (147-339:20-199) 120 130 140 150 160 170 pF1KA1 PAQPHLYLQRGACKTPPDGSLKLQEGSSGHSAALQVPCYAKESSLGEPELPPDSDTVGMD : ::..: . ... : .: : :: NP_001 MPAPVEGTDFPGAGRQAWGSPALSLP--VAPPAVSPPSVPLPSHQVG-- 10 20 30 40 180 190 200 210 220 230 pF1KA1 SSYLSVKEAGVKGPQDRASSDLPSPLEKADSESNKGKKRRNRTTFTSYQLEELEKVFQKT . .:: : :: .... :. :. : :.::::::::.:::..::..:. . NP_001 AMFLSPGE----GPATEGGGLGPG------EEAPKKKHRRNRTTFTTYQLHQLERAFEAS 50 60 70 80 90 240 250 260 270 280 290 pF1KA1 HYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERF--GQMQQVRTHFSTAYELPLL ::::::.::.:: .. : :.::::::::::::::..::. :. . .. : ::. NP_001 HYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWRRQERLESGSGAVAAPRLPEAPALPF- 100 110 120 130 140 150 300 310 320 330 340 350 pF1KA1 TRAENYAQIQNPSWLGNNGAASP-VPACVVPCDPVPACMSPHAHPPGSGASSVTDFLSVS .: .. .: ::: . : : .: . : . : ..::: : NP_001 ARPPAMSLPLEP-WLGPGPPAVPGLPRLLGPGPGLQASFGPHAFAPTFADGFALEEASLR 160 170 180 190 200 210 360 370 380 390 400 410 pF1KA1 GAGSHVGQTHMGSLFGAASLSPGLNGYELNGEPDRKTSSIAALRMKAKEHSAAISWAT NP_001 LLAKEHAQALDRAWPPA 220 230 >>XP_016883326 (OMIM: 122000,148300,605020,614195) PREDI (280 aa) initn: 402 init1: 339 opt: 366 Z-score: 202.3 bits: 45.8 E(85289): 0.00016 Smith-Waterman score: 366; 42.8% identity (58.2% similar) in 194 aa overlap (97-276:44-227) 70 80 90 100 110 120 pF1KA1 GAGQQDLATPLESGAGARGSFNKFQPQPSTPQPQPPPQPQPQQQQPQPQPPAQPHL---Y : : : : . . : : : : XP_016 SRALVPGGSPRGSRPRGFAITDLLGLEAELPAPAGPGQGSGCEG-PAVAPCPGPGLDGSS 20 30 40 50 60 70 130 140 150 160 170 180 pF1KA1 LQRGACKTPPDGSLKLQEG-SSGHSAALQVPCYAKESSLGEPELPPDSDTVGMDSSYLSV : ::: : : : : : .. :: ..:: . : ::: . . . XP_016 LARGAL---PLG-LGLLCGFGTQPPAAARAPCLLLADV---PFLPPRGPEPA--APLAPS 80 90 100 110 120 190 200 210 220 230 pF1KA1 KEAGVKGPQDRA----SSDLPSPLE-----KADSESNKGKKRRNRTTFTSYQLEELEKVF . . : : :. .:: : : ::. .: ::::.::.::..:::::::.: XP_016 RPPPALGRQKRSDSVSTSDEDSQSEDRNDLKASPTLGKRKKRRHRTVFTAHQLEELEKAF 130 140 150 160 170 180 240 250 260 270 280 290 pF1KA1 QKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRE-RFGQMQQVRTHFSTAYELP ...:::::::::.::..:.: : :.::::::::::::::: :.: XP_016 SEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKRWGGSSVMAEYGLYGAMVR 190 200 210 220 230 240 300 310 320 330 340 350 pF1KA1 LLTRAENYAQIQNPSWLGNNGAASPVPACVVPCDPVPACMSPHAHPPGSGASSVTDFLSV XP_016 HCIPLPDSVLNSAEGGLLGSCAPWLLEGETLGCREMK 250 260 270 280 411 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 11:21:55 2016 done: Thu Nov 3 11:21:57 2016 Total Scan time: 10.010 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]