FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1805, 567 aa 1>>>pF1KA1805 567 - 567 aa - 567 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.4176+/-0.000932; mu= 0.2339+/- 0.055 mean_var=241.5002+/-59.558, 0's: 0 Z-trim(111.5): 30 B-trim: 650 in 1/53 Lambda= 0.082531 statistics sampled from 12448 (12463) to 12448 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.723), E-opt: 0.2 (0.383), width: 16 Scan time: 2.170 The best scores are: opt bits E(32554) CCDS1758.1 ZNF512 gene_id:84450|Hs108|chr2 ( 567) 3872 474.4 1.6e-133 CCDS59429.1 ZNF512 gene_id:84450|Hs108|chr2 ( 490) 3360 413.4 3.3e-115 CCDS59428.1 ZNF512 gene_id:84450|Hs108|chr2 ( 538) 2856 353.4 4.1e-97 CCDS13548.1 ZNF512B gene_id:57473|Hs108|chr20 ( 892) 1273 165.1 3.3e-40 >>CCDS1758.1 ZNF512 gene_id:84450|Hs108|chr2 (567 aa) initn: 3872 init1: 3872 opt: 3872 Z-score: 2510.5 bits: 474.4 E(32554): 1.6e-133 Smith-Waterman score: 3872; 100.0% identity (100.0% similar) in 567 aa overlap (1-567:1-567) 10 20 30 40 50 60 pF1KA1 MSSRLGAVPATSGPTTFKQQRSTRIVGAKNSRTQCSIKDNSFQYTIPHDDSLSGSSSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 MSSRLGAVPATSGPTTFKQQRSTRIVGAKNSRTQCSIKDNSFQYTIPHDDSLSGSSSASS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 CEPVSDFPASFRKSTYWMKMRRIKPAATSHVEGSGGVSAKGKRKPRQEEDEDYREFPQKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 CEPVSDFPASFRKSTYWMKMRRIKPAATSHVEGSGGVSAKGKRKPRQEEDEDYREFPQKK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 HKLYGRKQRPKTQPNPKSQARRIRKEPPVYAAGSLEEQWYLEIVDKGSVSCPTCQAVGRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 HKLYGRKQRPKTQPNPKSQARRIRKEPPVYAAGSLEEQWYLEIVDKGSVSCPTCQAVGRK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 TIEGLKKHMENCKQEMFTCHHCGKQLRSLAGMKYHVMANHNSLPILKAGDEIDEPSERER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 TIEGLKKHMENCKQEMFTCHHCGKQLRSLAGMKYHVMANHNSLPILKAGDEIDEPSERER 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 LRTVLKRLGKLRCMRESCSSSFTSIMGYLYHVRKCGKGAAELEKMTLKCHHCGKPYRSKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 LRTVLKRLGKLRCMRESCSSSFTSIMGYLYHVRKCGKGAAELEKMTLKCHHCGKPYRSKA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 GLAYHLRSEHGPISFFPESGQPECLKEMNLESKSGGRVQRRSAKIAVYHLQELASAELAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 GLAYHLRSEHGPISFFPESGQPECLKEMNLESKSGGRVQRRSAKIAVYHLQELASAELAK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 EWPKRKVLQDLVPDDRKLKYTRPGLPTFSQEVLHKWKTDIKKYHRIQCPNQGCEAVYSSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 EWPKRKVLQDLVPDDRKLKYTRPGLPTFSQEVLHKWKTDIKKYHRIQCPNQGCEAVYSSV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 SGLKAHLGSCTLGNFVAGKYKCLLCQKEFVSESGVKYHINSVHAEDWFVVNPTTTKSFEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 SGLKAHLGSCTLGNFVAGKYKCLLCQKEFVSESGVKYHINSVHAEDWFVVNPTTTKSFEK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 LMKIKQRQQEEEKRRQQHRSRRSLRRRQQPGIELPETELSLRVGKDQRRNNEELVVSASC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 LMKIKQRQQEEEKRRQQHRSRRSLRRRQQPGIELPETELSLRVGKDQRRNNEELVVSASC 490 500 510 520 530 540 550 560 pF1KA1 KEPEQEPVPAQFQKVKPPKTNHKRGRK ::::::::::::::::::::::::::: CCDS17 KEPEQEPVPAQFQKVKPPKTNHKRGRK 550 560 >>CCDS59429.1 ZNF512 gene_id:84450|Hs108|chr2 (490 aa) initn: 3360 init1: 3360 opt: 3360 Z-score: 2181.9 bits: 413.4 E(32554): 3.3e-115 Smith-Waterman score: 3360; 100.0% identity (100.0% similar) in 490 aa overlap (78-567:1-490) 50 60 70 80 90 100 pF1KA1 HDDSLSGSSSASSCEPVSDFPASFRKSTYWMKMRRIKPAATSHVEGSGGVSAKGKRKPRQ :::::::::::::::::::::::::::::: CCDS59 MKMRRIKPAATSHVEGSGGVSAKGKRKPRQ 10 20 30 110 120 130 140 150 160 pF1KA1 EEDEDYREFPQKKHKLYGRKQRPKTQPNPKSQARRIRKEPPVYAAGSLEEQWYLEIVDKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 EEDEDYREFPQKKHKLYGRKQRPKTQPNPKSQARRIRKEPPVYAAGSLEEQWYLEIVDKG 40 50 60 70 80 90 170 180 190 200 210 220 pF1KA1 SVSCPTCQAVGRKTIEGLKKHMENCKQEMFTCHHCGKQLRSLAGMKYHVMANHNSLPILK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SVSCPTCQAVGRKTIEGLKKHMENCKQEMFTCHHCGKQLRSLAGMKYHVMANHNSLPILK 100 110 120 130 140 150 230 240 250 260 270 280 pF1KA1 AGDEIDEPSERERLRTVLKRLGKLRCMRESCSSSFTSIMGYLYHVRKCGKGAAELEKMTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 AGDEIDEPSERERLRTVLKRLGKLRCMRESCSSSFTSIMGYLYHVRKCGKGAAELEKMTL 160 170 180 190 200 210 290 300 310 320 330 340 pF1KA1 KCHHCGKPYRSKAGLAYHLRSEHGPISFFPESGQPECLKEMNLESKSGGRVQRRSAKIAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 KCHHCGKPYRSKAGLAYHLRSEHGPISFFPESGQPECLKEMNLESKSGGRVQRRSAKIAV 220 230 240 250 260 270 350 360 370 380 390 400 pF1KA1 YHLQELASAELAKEWPKRKVLQDLVPDDRKLKYTRPGLPTFSQEVLHKWKTDIKKYHRIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 YHLQELASAELAKEWPKRKVLQDLVPDDRKLKYTRPGLPTFSQEVLHKWKTDIKKYHRIQ 280 290 300 310 320 330 410 420 430 440 450 460 pF1KA1 CPNQGCEAVYSSVSGLKAHLGSCTLGNFVAGKYKCLLCQKEFVSESGVKYHINSVHAEDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 CPNQGCEAVYSSVSGLKAHLGSCTLGNFVAGKYKCLLCQKEFVSESGVKYHINSVHAEDW 340 350 360 370 380 390 470 480 490 500 510 520 pF1KA1 FVVNPTTTKSFEKLMKIKQRQQEEEKRRQQHRSRRSLRRRQQPGIELPETELSLRVGKDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 FVVNPTTTKSFEKLMKIKQRQQEEEKRRQQHRSRRSLRRRQQPGIELPETELSLRVGKDQ 400 410 420 430 440 450 530 540 550 560 pF1KA1 RRNNEELVVSASCKEPEQEPVPAQFQKVKPPKTNHKRGRK :::::::::::::::::::::::::::::::::::::::: CCDS59 RRNNEELVVSASCKEPEQEPVPAQFQKVKPPKTNHKRGRK 460 470 480 490 >>CCDS59428.1 ZNF512 gene_id:84450|Hs108|chr2 (538 aa) initn: 3022 init1: 2848 opt: 2856 Z-score: 1857.0 bits: 353.4 E(32554): 4.1e-97 Smith-Waterman score: 3595; 94.9% identity (94.9% similar) in 567 aa overlap (1-567:1-538) 10 20 30 40 50 60 pF1KA1 MSSRLGAVPATSGPTTFKQQRSTRIVGAKNSRTQCSIKDNSFQYTIPHDDSLSGSSSASS :::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::: CCDS59 MSSRLGAVPATSGPTTFKQQRSTRIVGAKN-RTQCSIKDNSFQYTIPHDDSLSGSSSASS 10 20 30 40 50 70 80 90 100 110 120 pF1KA1 CEPVSDFPASFRKSTYWMKMRRIKPAATSHVEGSGGVSAKGKRKPRQEEDEDYREFPQKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 CEPVSDFPASFRKSTYWMKMRRIKPAATSHVEGSGGVSAKGKRKPRQEEDEDYREFPQKK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KA1 HKLYGRKQRPKTQPNPKSQARRIRKEPPVYAAGSLEEQWYLEIVDKGSVSCPTCQAVGRK ::::: ::::::::::::::::::::::::::: CCDS59 HKLYG----------------------------SLEEQWYLEIVDKGSVSCPTCQAVGRK 120 130 140 150 190 200 210 220 230 240 pF1KA1 TIEGLKKHMENCKQEMFTCHHCGKQLRSLAGMKYHVMANHNSLPILKAGDEIDEPSERER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 TIEGLKKHMENCKQEMFTCHHCGKQLRSLAGMKYHVMANHNSLPILKAGDEIDEPSERER 160 170 180 190 200 210 250 260 270 280 290 300 pF1KA1 LRTVLKRLGKLRCMRESCSSSFTSIMGYLYHVRKCGKGAAELEKMTLKCHHCGKPYRSKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 LRTVLKRLGKLRCMRESCSSSFTSIMGYLYHVRKCGKGAAELEKMTLKCHHCGKPYRSKA 220 230 240 250 260 270 310 320 330 340 350 360 pF1KA1 GLAYHLRSEHGPISFFPESGQPECLKEMNLESKSGGRVQRRSAKIAVYHLQELASAELAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 GLAYHLRSEHGPISFFPESGQPECLKEMNLESKSGGRVQRRSAKIAVYHLQELASAELAK 280 290 300 310 320 330 370 380 390 400 410 420 pF1KA1 EWPKRKVLQDLVPDDRKLKYTRPGLPTFSQEVLHKWKTDIKKYHRIQCPNQGCEAVYSSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 EWPKRKVLQDLVPDDRKLKYTRPGLPTFSQEVLHKWKTDIKKYHRIQCPNQGCEAVYSSV 340 350 360 370 380 390 430 440 450 460 470 480 pF1KA1 SGLKAHLGSCTLGNFVAGKYKCLLCQKEFVSESGVKYHINSVHAEDWFVVNPTTTKSFEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SGLKAHLGSCTLGNFVAGKYKCLLCQKEFVSESGVKYHINSVHAEDWFVVNPTTTKSFEK 400 410 420 430 440 450 490 500 510 520 530 540 pF1KA1 LMKIKQRQQEEEKRRQQHRSRRSLRRRQQPGIELPETELSLRVGKDQRRNNEELVVSASC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 LMKIKQRQQEEEKRRQQHRSRRSLRRRQQPGIELPETELSLRVGKDQRRNNEELVVSASC 460 470 480 490 500 510 550 560 pF1KA1 KEPEQEPVPAQFQKVKPPKTNHKRGRK ::::::::::::::::::::::::::: CCDS59 KEPEQEPVPAQFQKVKPPKTNHKRGRK 520 530 >>CCDS13548.1 ZNF512B gene_id:57473|Hs108|chr20 (892 aa) initn: 1068 init1: 626 opt: 1273 Z-score: 835.3 bits: 165.1 E(32554): 3.3e-40 Smith-Waterman score: 1273; 41.0% identity (65.8% similar) in 517 aa overlap (14-515:354-861) 10 20 30 pF1KA1 MSSRLGAVPATSGPTTFKQQRSTRIVGAKNSRTQCSI----KD : :: : . .: : : : CCDS13 VLLTRSENKAPRATGRNSGKKRAADSLDTCPIPPKQARPENGEYGPSSMGQSSAFQLSAD 330 340 350 360 370 380 40 50 60 70 80 90 pF1KA1 NSFQYTIPHDDSLSGSSSASSCEPVSDFPASFRKSTYWMKMRRIKPAATSHVEGSGGVSA .: : . .: . .. :.: . ... . :.. : . . :: . CCDS13 TSSGSLSPGSRPSGGMEALKAAGPASPPEEDPERTKHRRKQKTPKKFTGEQPSISGTFGL 390 400 410 420 430 440 100 110 120 130 140 150 pF1KA1 KGKRKPRQEEDEDYREFPQKKHKLYGRKQ-RPKTQPNPKSQARRIRKEPPVYAA----GS :: : ::. : .::.. : .. : :. : . . :: :. .: :. CCDS13 KGLVKA---EDKA-RVHRSKKQEGPGPEDARKKVPAAPIT----VSKEAPAPVAHPAPGG 450 460 470 480 490 160 170 180 190 200 210 pF1KA1 LEEQWYLEIVDKGSVSCPTCQAVGRKTIEGLKKHMENCK--QEMFTCHHCGKQLRSLAGM :::: : ..: . ::::..: :::. ::::::: :. :. . :.:: ::..: ::. CCDS13 PEEQWQRAIHERGEAVCPTCNVVTRKTLVGLKKHMEVCQKLQDALKCQHCRKQFKSKAGL 500 510 520 530 540 550 220 230 240 250 260 270 pF1KA1 KYHVMANHNSLPILKAGDEIDEPSERERLRTVLKRLGKLRCMRESCSSSFTSIMGYLYHV .::.::.:.. : ..: : :::::: :::..:.::: .:.:...:.:.::: :: CCDS13 NYHTMAEHSAKPSDAEASEGGEQEERERLRKVLKQMGRLRCPQEGCGAAFSSLMGYQYHQ 560 570 580 590 600 610 280 290 300 310 320 330 pF1KA1 RKCGKGAAELEKMTLKCHHCGKPYRSKAGLAYHLRSEH-GPISFFPESGQPECLKEMNLE :.::: :... .. : :::: :::::: ::.:::: .: : . .:: ...: CCDS13 RRCGKPPCEVDSPSFPCTHCGKTYRSKAGHDYHVRSEHTAPPPEEPTDKSPEAEDPLGVE 620 630 640 650 660 670 340 350 360 370 380 390 pF1KA1 SKSGGRVQRRSAKIAVYHLQELASAELAKEWPKRKVLQDLVPDDRKLKYTRPGLPTFSQE .:::.: ::..::.::::.: :::..: ::.. .::::. .:.::::::::.. . CCDS13 RTPSGRVRRTSAQVAVFHLQEIAEDELARDWTKRRMKDDLVPETARLNYTRPGLPTLNPQ 680 690 700 710 720 730 400 410 420 430 440 450 pF1KA1 VLHKWKTDIKKYHRIQCPNQGCEAVYSSVSGLKAHLGSCTLGNFVAGKYKCLLCQKEFVS .:. ::...:. ...:::. :::.:::::::::::.::. : .::::.:::: ::: : CCDS13 LLEAWKNEVKEKGHVNCPNDCCEAIYSSVSGLKAHLASCSKGAHLAGKYRCLLCPKEFSS 740 750 760 770 780 790 460 470 480 490 500 pF1KA1 ESGVKYHINSVHAEDWFVVN---PTTTKSFEKLMKIKQRQQEEEKRRQQHRSRRSLRRRQ :::::::: ..:::.:: .. : .: ..:. :..... ... :. . : . CCDS13 ESGVKYHILKTHAENWFRTSADPPPKHRSQDSLVPKKEKKKNLAGGKKRGRKPKE-RTPE 800 810 820 830 840 850 510 520 530 540 550 560 pF1KA1 QPGIELPETELSLRVGKDQRRNNEELVVSASCKEPEQEPVPAQFQKVKPPKTNHKRGRK .: .:: CCDS13 EPVAKLPPRRDDWPPGCRDKGARGSTGRKVGVSKAPEK 860 870 880 890 567 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 22:04:49 2016 done: Wed Nov 2 22:04:50 2016 Total Scan time: 2.170 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]