Result of FASTA (omim) for
pF1KA1816
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1816, 1133 aa
1>>>pF1KA1816 1133 - 1133 aa - 1133 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.3714+/-0.000451; mu= -19.5655+/- 0.028
mean_var=553.5752+/-115.732, 0's: 0 Z-trim(123.6): 190 B-trim: 74 in 1/55
Lambda= 0.054511
statistics sampled from 43556 (43773) to 43556 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.776), E-opt: 0.2 (0.513), width: 16
Scan time: 14.520
The best scores are: opt bits E(85289)
NP_061187 (OMIM: 608991) mastermind-like protein 3 (1133) 7696 620.9 1.3e-176
NP_055572 (OMIM: 605424) mastermind-like protein 1 (1016) 959 91.1 3.8e-17
NP_115803 (OMIM: 607537) mastermind-like protein 2 (1156) 651 66.9 8.2e-10
XP_011541327 (OMIM: 607537) PREDICTED: mastermind- ( 735) 624 64.6 2.5e-09
XP_016883233 (OMIM: 605299) PREDICTED: nuclear rec (2051) 492 54.6 7.5e-06
XP_011541326 (OMIM: 607537) PREDICTED: mastermind- ( 928) 479 53.3 8.2e-06
XP_011527029 (OMIM: 605299) PREDICTED: nuclear rec (2056) 490 54.4 8.4e-06
XP_011541325 (OMIM: 607537) PREDICTED: mastermind- (1009) 479 53.3 8.7e-06
XP_011527028 (OMIM: 605299) PREDICTED: nuclear rec (2057) 486 54.1 1e-05
XP_016883239 (OMIM: 605299) PREDICTED: nuclear rec (1094) 443 50.5 6.6e-05
XP_016883238 (OMIM: 605299) PREDICTED: nuclear rec (1650) 443 50.6 9.1e-05
XP_016883237 (OMIM: 605299) PREDICTED: nuclear rec (1651) 443 50.6 9.1e-05
XP_016883231 (OMIM: 605299) PREDICTED: nuclear rec (2082) 445 50.9 9.8e-05
XP_016883235 (OMIM: 605299) PREDICTED: nuclear rec (1999) 443 50.7 0.00011
XP_016883232 (OMIM: 605299) PREDICTED: nuclear rec (2058) 443 50.7 0.00011
XP_016883230 (OMIM: 605299) PREDICTED: nuclear rec (2086) 443 50.7 0.00011
XP_016883228 (OMIM: 605299) PREDICTED: nuclear rec (2087) 443 50.7 0.00011
XP_016883229 (OMIM: 605299) PREDICTED: nuclear rec (2087) 443 50.7 0.00011
XP_016883236 (OMIM: 605299) PREDICTED: nuclear rec (1907) 435 50.0 0.00016
XP_016883234 (OMIM: 605299) PREDICTED: nuclear rec (2039) 409 48.0 0.00069
NP_001229468 (OMIM: 605299) nuclear receptor coact (1070) 395 46.7 0.00089
XP_016883240 (OMIM: 605299) PREDICTED: nuclear rec (1070) 395 46.7 0.00089
XP_006723818 (OMIM: 605299) PREDICTED: nuclear rec (1975) 395 46.9 0.0014
NP_001305169 (OMIM: 605299) nuclear receptor coact (2063) 395 46.9 0.0015
NP_054790 (OMIM: 605299) nuclear receptor coactiva (2063) 395 46.9 0.0015
XP_011527023 (OMIM: 605299) PREDICTED: nuclear rec (2068) 393 46.8 0.0017
XP_011537078 (OMIM: 147920,602113) PREDICTED: hist (5525) 381 46.1 0.0069
XP_006719679 (OMIM: 147920,602113) PREDICTED: hist (5536) 381 46.1 0.0069
XP_005269219 (OMIM: 147920,602113) PREDICTED: hist (5537) 381 46.1 0.0069
NP_003473 (OMIM: 147920,602113) histone-lysine N-m (5537) 381 46.1 0.0069
XP_006719677 (OMIM: 147920,602113) PREDICTED: hist (5540) 381 46.1 0.0069
XP_011537076 (OMIM: 147920,602113) PREDICTED: hist (5549) 381 46.1 0.0069
XP_011537075 (OMIM: 147920,602113) PREDICTED: hist (5552) 381 46.1 0.0069
XP_011537074 (OMIM: 147920,602113) PREDICTED: hist (5553) 381 46.1 0.0069
XP_011537073 (OMIM: 147920,602113) PREDICTED: hist (5555) 381 46.1 0.0069
XP_011537072 (OMIM: 147920,602113) PREDICTED: hist (5556) 381 46.1 0.0069
>>NP_061187 (OMIM: 608991) mastermind-like protein 3 [Ho (1133 aa)
initn: 7696 init1: 7696 opt: 7696 Z-score: 3291.5 bits: 620.9 E(85289): 1.3e-176
Smith-Waterman score: 7696; 99.9% identity (99.9% similar) in 1133 aa overlap (1-1133:1-1133)
10 20 30 40 50 60
pF1KA1 MGDFAAPAAAANGSSICINSSLNSSLGGAGIGVNNTPNSTPAAPSSNHPAAGGCGGSGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MGDFAAPAAAANGSSICINSSLNSSLGGAGIGVNNTPNSTPAAPSSNHPAAGGCGGSGGP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 GGGSAAVPKHSTVVERLRQRIEGCRRHHVNCENRYQQAQVEQLELERRDTVSLYQRTLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 GGGSAAVPKHSTVVERLRQRIEGCRRHHVNCENRYQQAQVEQLELERRDTVSLYQRTLEQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 RAKKSGAGTGKQQHPSKPQQDAEAASAEQRNHTLIMLQETVKRKLEGARSPLNGDQQNGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 RAKKSGAGTGKQQHPSKPQQDAEAASAEQRNHTLIMLQETVKRKLEGARSPLNGDQQNGA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 CDGNFSPTSKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNSGTHTPGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 CDGNFSPTSKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNSGTHTPGLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 EDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSETSLSNQNKLFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 EDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSETSLSNQNKLFS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 DINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPATETPLSQESASVKSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPATETPLSQESASVKSD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 PSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 PSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 PNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 PNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 LMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 QAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 QAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 LTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 EDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 EDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 AGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 AGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 RQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 RQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 TMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 TMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPAS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 GQGVGMVSGFGQSMLVNSAITQQHPQMKGPVGQALPRPQAPPRLQSLMGTVQQGAQSWQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 GQGVGMVSGFGQSMLVNSAITQQHPQMKGPVGQALPRPQAPPRLQSLMGTVQQGAQSWQQ
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA1 RSLQGMPGRTSGELGPFNNGASYPLQAGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 RSLQGMPGRTSGELGPFNNGASYPLQAGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA1 MGRQMMPSLPGQQGTSQARPMVMSGLSQGVPGMPAFSQHPAQQQIPSGSFAPSSQSQAYE
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
NP_061 MGRQMMPSLPGQQGTSQARPMVMSGLSQGVPGMPAFSQPPAQQQIPSGSFAPSSQSQAYE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130
pF1KA1 RNAPQDVSYNYSGDGAGGSFPGLPDGADLVDSIIKGGPGDEWMQELDELFGNP
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 RNAPQDVSYNYSGDGAGGSFPGLPDGADLVDSIIKGGPGDEWMQELDELFGNP
1090 1100 1110 1120 1130
>>NP_055572 (OMIM: 605424) mastermind-like protein 1 [Ho (1016 aa)
initn: 1055 init1: 366 opt: 959 Z-score: 428.8 bits: 91.1 E(85289): 3.8e-17
Smith-Waterman score: 1895; 35.5% identity (64.3% similar) in 1102 aa overlap (66-1132:12-1015)
40 50 60 70 80 90
pF1KA1 TPNSTPAAPSSNHPAAGGCGGSGGPGGGSAAVPKHSTVVERLRQRIEGCRRHHVNCENRY
:.:.::.:.::::.::: ::::: .:: ::
NP_055 MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARY
10 20 30 40
100 110 120 130 140 150
pF1KA1 QQAQVEQLELERRDTVSLYQRTLEQRAKKSGAG----TGKQQHPSKPQQDAEAASAEQRN
. .. :.:::::. : .:.:: .. .::..: .. :. : .::.. ...
NP_055 EAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAATAPAPAAPAPRLDAADGPEHG
50 60 70 80 90 100
160 170 180 190 200 210
pF1KA1 HTLIMLQETVKRKLEGARSPLNGDQQNGACDGNFSPTSKRIRKDISAGMEAINNLPSNMP
. :..::::.:..: :: ::::::: :.. : :. :.. :. :: :.
NP_055 RPATHLHDTVKRNLDSATSPQNGDQQNGY--GDLFPGHKKTRREAPLGV-AI----SSNG
110 120 130 140 150
220 230 240 250 260
pF1KA1 LPSASPLHQLDLKPSLP--LQNSGTHTPGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTIL
:: :::: : : ::: ::.:: :. :: ..:.:. :: . .: .:: :. .:: .
NP_055 LPPASPLGQSD-KPSGADALQSSGKHSLGL-DSLNKK-RLADSSLHLNGGSNPSESFPLS
160 170 180 190 200 210
270 280 290 300 310 320
pF1KA1 QSKDLKQEPLDDPTCIDTSETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLF
.:.:::::..: :. :. .. .:..:. :.:::.:::.:::.:: .::..:..:::
NP_055 LNKELKQEPVEDLPCMITGTVGSISQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLF
220 230 240 250 260 270
330 340 350 360 370 380
pF1KA1 NEDFEEKKEPEFSQPATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPF---S
::::::::.:: : ::.:::.:. ..:.. : . : . ..::::.: .:.: : :
NP_055 NEDFEEKKDPESSGSATQTPLAQD-INIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGPS
280 290 300 310 320 330
390 400 410 420 430 440
pF1KA1 TVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPN--QAHTPGQAPPRPGNGYLLNPAA
.. ..:. ::.... . . ...: ...: .:: : . .: : : .: :.
NP_055 SAPVSTDSPSLGGSQTLFHTSGQP---RADNP-SPNLMPASAQAQNAQRALAGVVL-PS-
340 350 360 370 380
450 460 470 480 490 500
pF1KA1 VTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQ
.:: . .:..: :.::.:.::.:.. .:. :. ::
NP_055 -------QGPGG--ASELSSAHQLQQIAAKQKR---------------EQMLQNPQQATP
390 400 410 420
510 520 530 540 550 560
pF1KA1 QQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNN
.: :.:. :: : . . ::: :: : : :.:.. .. : .:. . .
NP_055 APAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGP
430 440 450 460 470 480
570 580 590 600 610 620
pF1KA1 YLPQNHMNMINQQP-NNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNP
:: .:.:....:: .::. :: :.: ..: :::::::.:..:: .: : .. .:
NP_055 YLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQ--GSPGSGQSKPA
490 500 510 520 530
630 640 650 660 670 680
pF1KA1 LMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAA
:: :. :: .:.:..:. :.::: : :.: . .
NP_055 LMAYLPQQL------------------------SHISHEQNSLFLMKPKP-GNMP--FRS
540 550 560 570
690 700 710 720 730 740
pF1KA1 LPSHGQEQHPVGLP-RTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQ--MLI
: ::::.: ..: .. . .. ::. . :... ..: .:.:: :::.::: .:.
NP_055 LVPPGQEQNPSSVPVQAQATSVGTQPPAVS--VASSHNSSP-YLSSQQQAAVMKQHQLLL
580 590 600 610 620
750 760 770 780 790
pF1KA1 DQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQ--SHL---PRQHLQPQRNPYPVQQ
::. : ..:.:. : .:.: :.::..::::. :: :: : :. .: .. .: ::
NP_055 DQQKQ--REQQQKHL-QQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFP-QQ
630 640 650 660 670 680
800 810 820 830 840 850
pF1KA1 VNQFQGSPQDIAAVRSQAALQSMRTS--RLMAQNAGMMGIGPSQNP-GTMATAAAQSEMG
:.:: :: ::: .. .: .: :.. : ...: .::.. ... : ..:.. :
NP_055 VGQFTGSS---AAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRG
690 700 710 720 730 740
860 870 880 890 900 910
pF1KA1 LAPYSTTPT-SQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFG
.: . . . : ..:.:..:.::.. .: .. :...:. ::: ::.... ...:
NP_055 VAQFPGSQNMPQSSLYGMASGITQIVAQPPPQA---TNGHAHIPRQTNVGQNTSVSAAYG
750 760 770 780 790
920 930 940 950 960 970
pF1KA1 QSMLVNSAITQQHPQMKGPVGQALPRPQAPPRLQSLMGTVQQGAQSWQQRSLQGMPGRTS
:. : .:...::: :: .. .: .: .: :.. :: :.. :::.... .. :.:
NP_055 QNSLGSSGLSQQH--NKGTLNPGLTKPPVP-RVSPAMG--GQNS-SWQHQGMPNLSGQTP
800 810 820 830 840 850
980 990 1000 1010 1020
pF1KA1 GE--LGPFNNGASYPLQAGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMPSL
:. ..::. ..:. .: : :. :: .::.: : . . ::.: ...: .
NP_055 GNSNVSPFTAASSFHMQ--QQAHLKMSSPQ-FSQAV--PNRPMAPMSSAAAVG-SLLPPV
860 870 880 890 900
1030 1040 1050 1060 1070 1080
pF1KA1 PGQQGTSQARPMV--------MSGLSQGVPGMPAFSQHPAQQQIPSGSFAPSSQSQAYE-
.:: :: : . ::: . : . :::: ::.:. :. : .:::
NP_055 SAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQM---GGRAGLHCTQAYPV
910 920 930 940 950 960
1090 1100 1110 1120 1130
pF1KA1 RNAPQDVSYNYSGDGAGGSFPGLPDGADLVDSIIKGGPGDEWMQELDELFGNP
:.: :.. . :::. .:... .. .::.::..:. ..:::..::.:.:.
NP_055 RTAGQELPFAYSGQPGGSGLSSVAGHTDLIDSLLKNRTSEEWMSDLDDLLGSQ
970 980 990 1000 1010
>>NP_115803 (OMIM: 607537) mastermind-like protein 2 [Ho (1156 aa)
initn: 1453 init1: 223 opt: 651 Z-score: 297.1 bits: 66.9 E(85289): 8.2e-10
Smith-Waterman score: 1079; 28.2% identity (52.8% similar) in 1235 aa overlap (41-1103:7-1122)
20 30 40 50 60
pF1KA1 ANGSSICINSSLNSSLGGAGIGVNNTPNSTPAAPSSNHPAAGGCGGSGGPG--GGSAAVP
: :: ::: ::..: : ::....:
NP_115 MGDTAPPQAP------AGGLGGASGAGLLGGGSVTP
10 20 30
70 80 90 100 110 120
pF1KA1 K-HSTVVERLRQRIEGCRRHHVNCENRYQQAQVEQLELERRDTVSLYQRTLE-QRAKKSG
. ::..::::: :: ::.::..::.::.....:. . ::..:..: . . . : :.:.:
NP_115 RVHSAIVERLRARIAVCRQHHLSCEGRYERGRAESSDRERESTLQLLSLVQHGQGARKAG
40 50 60 70 80 90
130
pF1KA1 AGTG---------------------------------------KQQH------------P
: .:::
NP_115 KHTKATATAATTTAPPPPPAAPPAASQAAATAAPPPPPDYHHHHQQHLLNSSNNGGSGGI
100 110 120 130 140 150
140 150 160 170 180 190
pF1KA1 SKPQQDAEAASAEQRNHTLIMLQETVKRKLEGARSPLNGDQQNGACDGNFSPTSKRIR--
. :: .. ..::: .:: :: ..::: :: :. . :: :..: ::::
NP_115 NGEQQPPASTPGDQRNSALIALQGSLKRKQVVNLSPANSKRPNGFVDNSFLDI-KRIRVG
160 170 180 190 200
200 210 220 230 240 250
pF1KA1 KDISAGMEA--INNLPSNMPLPSASPLHQLDLKPSLPLQNSGTHTPGLLEDLSKNGRLPE
...:::. . ::: :.. . .. :. : :. . : : ::.:: . : . : : :
NP_115 ENLSAGQGGLQINNGQSQI-MSGTLPMSQAPLRKTNTLP-SHTHSPG--NGLFNMG-LKE
210 220 230 240 250 260
260 270 280 290 300
pF1KA1 IKLPVN---GCSDLEDSFTILQSKDLKQEPLDDP--TCIDTSETSLSNQNKLFSDINLND
.: . .:: :. . : . . .. ::: .: : :. .: ..:
NP_115 VKKEPGETLSCSKHMDG-QMTQENIFPNRYGDDPGEQLMDPELQELFNELTNISVPPMSD
270 280 290 300 310 320
310 320 330 340 350 360
pF1KA1 QEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPATETP-LSQESASVKSDPSHSP
: ...:. :. .:: :: :. .. :: .: : : .:. .::. .::
NP_115 LELENMIN---ATIKQDDP---FNIDLGQQ-----SQRSTPRPSLPMEKIVIKSE--YSP
330 340 350 360 370
370 380 390 400 410 420
pF1KA1 -FAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPNQA
... :::: :: :.:: :: ...: : .::: :..:..
NP_115 GLTQGPSGSPQLRPPSAGPAFSMANSALS-------------TSSPI------PSVPQS-
380 390 400 410
430 440 450 460 470 480
pF1KA1 HTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPS-SDMSPAEQLKQMAAQQQQRAKLMQ
:: :. :.: :: :.:: ...: :.::::.::..::.:..
NP_115 ----QAQPQTGSG-------------ASR--ALPSWQEVSHAQQLKQIAANRQQHARM--
420 430 440
490 500 510 520 530 540
pF1KA1 QKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAF
::.:::: : .::: : ..: . : :: :: . :.:
NP_115 -----------------QQHQQQH--QPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTF
450 460 470 480 490
550 560 570 580 590
pF1KA1 NNQNPIVPPMANNL-QKTTMNNYL----PQ---NHMNMINQQ-PNNLGTNSLNKQHNILT
. :. .: .:.. :. .: ::. :. .:.... :: :..:. . .:. : .
NP_115 SPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAME
500 510 520 530 540 550
600 610 620 630 640 650
pF1KA1 --YGNTKPLTHFNADLSQRMTPPV-ANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQ
:::::: :::.: .... : : . :: :. : :::::::::::::::::: :
NP_115 PRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQ
560 570 580 590 600 610
660 670 680 690
pF1KA1 LQAPR----------AHLSEDQKRLL----LMKQKGVMNQPMAYAALPSHGQEQHPVGLP
: . :. ...:. . ..:. ..: . .. :.:.: . :
NP_115 QQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQP
620 630 640 650 660 670
700 710 720
pF1KA1 RTTGPMQ----SSVP-------------PGSG-----------------GMVSGASPA--
. : : : .: : .: :. .: ::.
NP_115 AQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPN
680 690 700 710 720 730
730 740 750 760 770
pF1KA1 -------GPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILA--EQ
: :...:: ....:.:. .. : :.: . ::.:: :::.:: :.
NP_115 PCSNPNTGSGYMNSQQ--SLLNQQLMGKKQTL---QRQ--IMEQKQQLLLQQQMLADAEK
740 750 760 770 780
780 790 800 810 820
pF1KA1 QLQQSHLPRQHLQP-------QRNPYPVQQVNQFQGSPQDIAAVRSQAALQSMRTSRLMA
:... :. .: .:: .: . :..:. . :. .:: . . : ...
NP_115 IAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILT
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA1 QNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGM
:..... . . ...::. ..::. :.. : .::. :....::.:. :. : . .
NP_115 PNSSLLSTSHGTRMPSLSTAV--QNMGM--YGNLPCNQPNTYSVTSGMNQLTQQRNPKQL
850 860 870 880 890
890 900 910 920 930 940
pF1KA1 SITHNQAQGPRQPASG-QGVGMVSGFGQSMLVNSAITQQHPQMKGPVGQALPRPQAPPRL
..:. . :: :. : .. . :. :: . . :: : .:.. .. ..: : :
NP_115 LANQNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQ--QLRPNLTHSMA-SMP----PQRT
900 910 920 930 940 950
950 960 970 980 990
pF1KA1 QSLMGTVQQGAQSWQQR---SLQGMPGRTSGELGPFNNGASY-PLQAGQPRLTKQHFPQ-
...: : . : .: .. : : ..: : .. :.: : :. : . .:.: :
NP_115 SNVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQR
960 970 980 990 1000 1010
1000 1010 1020 1030
pF1KA1 ------------------GLSQSVVDANTGTVRTLN--PAAMGRQMMPSLPGQQGTSQAR
.::.. . : .: :: : .. :..:.: .:.::
NP_115 AVAPPNQLTPAVQMRPMNQMSQTLNGQTMGPLRGLNLRPNQLSTQILPNL-NQSGT----
1020 1030 1040 1050 1060
1040 1050 1060 1070 1080 1090
pF1KA1 PMVMSGLSQGVPGMPAFSQHPAQQQIPSGSFAPSSQSQAYE-RNAPQDVSYNYSGDGAGG
::.:. :. .: :. ::. .:...:.:.. . .:..... .. .
NP_115 -----GLNQSRTGI---NQPPSLT--PSNFPSPNQSSRAFQGTDHSSDLAFDFLSQQNDN
1070 1080 1090 1100 1110
1100 1110 1120 1130
pF1KA1 SFPGLPDGADLVDSIIKGGPGDEWMQELDELFGNP
:.:
NP_115 MGPALNSDADFIDSLLKTEPGNDDWMKDINLDEILGNNS
1120 1130 1140 1150
>>XP_011541327 (OMIM: 607537) PREDICTED: mastermind-like (735 aa)
initn: 1453 init1: 223 opt: 624 Z-score: 288.4 bits: 64.6 E(85289): 2.5e-09
Smith-Waterman score: 841; 31.0% identity (51.3% similar) in 861 aa overlap (41-816:7-710)
20 30 40 50 60
pF1KA1 ANGSSICINSSLNSSLGGAGIGVNNTPNSTPAAPSSNHPAAGGCGGSGGPG--GGSAAVP
: :: ::: ::..: : ::....:
XP_011 MGDTAPPQAP------AGGLGGASGAGLLGGGSVTP
10 20 30
70 80 90 100 110 120
pF1KA1 K-HSTVVERLRQRIEGCRRHHVNCENRYQQAQVEQLELERRDTVSLYQRTLE-QRAKKSG
. ::..::::: :: ::.::..::.::.....:. . ::..:..: . . . : :.:.:
XP_011 RVHSAIVERLRARIAVCRQHHLSCEGRYERGRAESSDRERESTLQLLSLVQHGQGARKAG
40 50 60 70 80 90
130
pF1KA1 AGTG---------------------------------------KQQH------------P
: .:::
XP_011 KHTKATATAATTTAPPPPPAAPPAASQAAATAAPPPPPDYHHHHQQHLLNSSNNGGSGGI
100 110 120 130 140 150
140 150 160 170 180 190
pF1KA1 SKPQQDAEAASAEQRNHTLIMLQETVKRKLEGARSPLNGDQQNGACDGNFSPTSKRIR--
. :: .. ..::: .:: :: ..::: :: :. . :: :..: ::::
XP_011 NGEQQPPASTPGDQRNSALIALQGSLKRKQVVNLSPANSKRPNGFVDNSFLDI-KRIRVG
160 170 180 190 200
200 210 220 230 240 250
pF1KA1 KDISAGMEA--INNLPSNMPLPSASPLHQLDLKPSLPLQNSGTHTPGLLEDLSKNGRLPE
...:::. . ::: :.. . .. :. : :. . : : ::.:: . : . : : :
XP_011 ENLSAGQGGLQINNGQSQI-MSGTLPMSQAPLRKTNTLP-SHTHSPG--NGLFNMG-LKE
210 220 230 240 250 260
260 270 280 290 300
pF1KA1 IKLPVN---GCSDLEDSFTILQSKDLKQEPLDDP--TCIDTSETSLSNQNKLFSDINLND
.: . .:: :. . : . . .. ::: .: : :. .: ..:
XP_011 VKKEPGETLSCSKHMDG-QMTQENIFPNRYGDDPGEQLMDPELQELFNELTNISVPPMSD
270 280 290 300 310 320
310 320 330 340 350 360
pF1KA1 QEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPATETP-LSQESASVKSDPSHSP
: ...:. :. .:: :: :. .. :: .: : : .:. .::. .::
XP_011 LELENMINA---TIKQDDP---FNIDLGQQ-----SQRSTPRPSLPMEKIVIKSE--YSP
330 340 350 360 370
370 380 390 400 410 420
pF1KA1 -FAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPNQA
... :::: :: :.:: :: ...: : .::: :..:..
XP_011 GLTQGPSGSPQLRPPSAGPAFSMANSALS-------------TSSPI------PSVPQS-
380 390 400 410
430 440 450 460 470 480
pF1KA1 HTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPS-SDMSPAEQLKQMAAQQQQRAKLMQ
:: :. :.: :: :.:: ...: :.::::.::..::.:..
XP_011 ----QAQPQTGSG-------------ASR--ALPSWQEVSHAQQLKQIAANRQQHARM--
420 430 440
490 500 510 520 530 540
pF1KA1 QKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAF
::.:::: : .::: : ..: . : :: :: . :.:
XP_011 -----------------QQHQQQH--QPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTF
450 460 470 480 490
550 560 570 580 590
pF1KA1 NNQNPIVPPMANNL-QKTTMNNYL----PQ---NHMNMINQQ-PNNLGTNSLNKQHNILT
. :. .: .:.. :. .: ::. :. .:.... :: :..:. . .:. : .
XP_011 SPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAME
500 510 520 530 540 550
600 610 620 630 640 650
pF1KA1 --YGNTKPLTHFNADLSQRMTPPV-ANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQ
:::::: :::.: .... : : . :: :. : :::::::::::::::::: :
XP_011 PRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQ
560 570 580 590 600 610
660 670 680 690 700 710
pF1KA1 LQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGS
: .:. :.:
XP_011 QQ----------------QQQ----------------QQQ--------------------
720 730 740 750 760 770
pF1KA1 GGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAE
: :..: :. .:.... ::.:: ..:.:::::::: .
XP_011 -----------------QQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQ
620 630 640 650 660
780 790 800 810 820
pF1KA1 QQLQQSHLPRQHLQPQ---RNPYPVQQ---VNQFQGSPQDIAAVRSQAALQSMRTSRLMA
:: : : : : : : :.: :.:: ..:.:..: ::.. :.. :
XP_011 QQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQP--IAGMGYQVSQQQRQQPVGVS
670 680 690 700 710
830 840 850 860 870 880
pF1KA1 QNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGM
XP_011 MPDADNIESKCSCKGE
720 730
>>XP_016883233 (OMIM: 605299) PREDICTED: nuclear recepto (2051 aa)
initn: 499 init1: 201 opt: 492 Z-score: 226.0 bits: 54.6 E(85289): 7.5e-06
Smith-Waterman score: 506; 25.2% identity (49.6% similar) in 939 aa overlap (261-1109:8-868)
240 250 260 270 280
pF1KA1 NSGTHTPGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCI---DT
.::: .: : :. ... .: . . ::
XP_016 MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDT
10 20 30
290 300 310 320 330
pF1KA1 SETSLSNQNKLFSDI--NLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKK-EP-----
. :. ... .: . :..:.... .: . ..:: .. . . .. .: ::
XP_016 KSDSILEDSTIFVAFKGNIDDKDFKWKLDAILKNVP--NLLHMESSKLKVQKVEPWNSVR
40 50 60 70 80 90
340 350 360 370 380
pF1KA1 -EFSQP--ATET--PLSQESASVKSDPSHSPF-----AHVSMGSPQARPSS---SGP--P
:. : :.: :.: . . : . . .... : : .. .::
XP_016 VTFNIPREAAERLRILAQSNNQQLRDLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGA
100 110 120 130 140 150
390 400 410 420 430
pF1KA1 FSTVSTATSLPSVASTPAA---PNPASS--PANCAVQSPQT---PN---QAHTPGQAPPR
..: ...: .:: :. :::. : . :.: . :: : .:: :
XP_016 GNSVRMEAGFP-MASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQS
160 170 180 190 200 210
440 450 460 470 480 490
pF1KA1 PGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQ
. ::. . . :: .: : :.:. .:: . . . .::.::::::::
XP_016 DAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQ
220 230 240 250 260 270
500 510 520 530 540
pF1KA1 QQQQQQQQQQQ------QQHSNQT-SNWSP--LGPPSSPYGAAFTAEKPNSPMMYPQA--
::::::::::: :::..: .. : .: . : ... . :.. .. : :
XP_016 QQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWN-QLPSGALQPPPAQG
280 290 300 310 320 330
550 560 570 580 590
pF1KA1 -----FNNQN----PIVPPMANNLQ-KTTMNNYLPQNHMNMINQQPNNLGTNSLNKQH-N
::. :. :: ..:: . .. . .: : .:... .. : :
XP_016 SLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSH----PPPPYPFGSQQASQAHTN
340 350 360 370 380
600 610 620 630 640
pF1KA1 ILTYGN----TKPLTHFNADLSQRMTPPVANP---NKNPLM-PYIQQQQQQQQQQ--QQQ
. ..: : : . .:. :. .: ::.: : :: . .. .:
XP_016 FPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQT
390 400 410 420 430 440
650 660 670 680 690
pF1KA1 QQQQQPPPPQ-------LQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPV
:::. : ::: .: : . ... : :.: : : . .. :.: :
XP_016 QQQMGPRPPQNNPLPQGFQQPVSSPGRNP-----MVQQG--NVPPNFMVM----QQQPP-
450 460 470 480 490
700 710 720 730 740 750
pF1KA1 GLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQF
. :: .:. :: ::. :.:.:. .: .. . :: .:. :
XP_016 ----NQGP--QSLHPGLGGQ------ANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQH
500 510 520 530 540
760 770 780 790 800 810
pF1KA1 LREQRQQQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQQVNQFQGS---PQDIAAVRS
: :.: .: :: : . .::. .. :: :. :: .
XP_016 AGGQGAGPPQNQ-------MQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQ-VNLSNM
550 560 570 580 590
820 830 840 850 860 870
pF1KA1 QAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYNMST
:. :. :.::... .. ::: : :. :.. : : . :. . :
XP_016 QGQPQQGPPSQLMGMHQQIV---PSQ--GQMV----QQQGTLNPQNPMILSRAQL--MPQ
600 610 620 630 640
880 890 900 910 920 930
pF1KA1 GMTQMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQQHPQMKGPV
: ::. .: ..... . .. :.: : :: :.. : :: ::
XP_016 G--QMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMA--------------PHNQMMGPQ
650 660 670 680 690
940 950 960 970 980
pF1KA1 GQALPRPQAPPRLQSLMGTVQQGAQSWQQRSLQG----MPGRTSGELGPFNNGASYPLQ-
::.: : : ....: . .:: . :: . :. ::: .. :: : . .:
XP_016 GQVLL--QQNPMIEQIMTNQMQGNK--QQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQF
700 710 720 730 740
990 1000 1010 1020 1030 1040
pF1KA1 AGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMPS--LPGQQGTSQARPMVMS
.:: .. : .:: :. :. . . : .. .. : :: . :.: .
XP_016 TGQ--MSGQMLPQ---QGPVNNSPSQVMGIQGQVL-RPPGPSPHMAQQHGDPATTANNDV
750 760 770 780 790 800
1050 1060 1070 1080 1090 1100
pF1KA1 GLSQGVP--GMPAFSQHPAQQQIPSGSFAPSSQ--SQAYERNAPQDVSYNYSGDGAGGSF
.::: .: .. .. : . : .:. : ... .... ::: . . : ... . :.
XP_016 SLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPN-GNQMSCGQN
810 820 830 840 850
1110 1120 1130
pF1KA1 PGLPDGADLVDSIIKGGPGDEWMQELDELFGNP
::.: . :.
XP_016 PGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLN
860 870 880 890 900 910
>>XP_011541326 (OMIM: 607537) PREDICTED: mastermind-like (928 aa)
initn: 1433 init1: 223 opt: 479 Z-score: 225.4 bits: 53.3 E(85289): 8.2e-06
Smith-Waterman score: 841; 27.4% identity (53.0% similar) in 1011 aa overlap (206-1103:1-894)
180 190 200 210 220 230
pF1KA1 QQNGACDGNFSPTSKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNSGTH
. ...:. : .::.. . .:: : ::
XP_011 MSGTLPM-SQAPLRKTN---TLP---SHTH
10 20
240 250 260 270 280 290
pF1KA1 TPGLLEDLSKNGRLPEIKLPVN---GCSDLEDSFTILQSKDLKQEPLDDP--TCIDTSET
.:: . : . : : :.: . .:: :. . : . . .. ::: .:
XP_011 SPG--NGLFNMG-LKEVKKEPGETLSCSKHMDG-QMTQENIFPNRYGDDPGEQLMDPELQ
30 40 50 60 70
300 310 320 330 340
pF1KA1 SLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPATETP-
: :. .: ..: : ...:. :. .:: :: :. .. :: .: :
XP_011 ELFNELTNISVPPMSDLELENMIN---ATIKQDDP---FNIDLGQQ-----SQRSTPRPS
80 90 100 110 120
350 360 370 380 390 400
pF1KA1 LSQESASVKSDPSHSP-FAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPAS
: .:. .::. .:: ... :::: :: :.:: :: ...: : .:
XP_011 LPMEKIVIKSE--YSPGLTQGPSGSPQLRPPSAGPAFSMANSALS-------------TS
130 140 150 160 170
410 420 430 440 450 460
pF1KA1 SPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPS-SDMSPAEQ
:: :..:.. :: :. :.: :: :.:: ...: :.:
XP_011 SPI------PSVPQS-----QAQPQTGSG-------------ASR--ALPSWQEVSHAQQ
180 190 200
470 480 490 500 510 520
pF1KA1 LKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAA
:::.::..::.:.. ::.:::: : .::: : ..: .
XP_011 LKQIAANRQQHARM-------------------QQHQQQH--QPTNWSALPSSAGPSPGP
210 220 230 240
530 540 550 560 570
pF1KA1 FTAEKPNSPMMYPQAFNNQNPIVPPMANNL-QKTTMNNYL----PQ---NHMNMINQQ-P
: :: :: . :.:. :. .: .:.. :. .: ::. :. .:.... :: :
XP_011 FGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKP
250 260 270 280 290 300
580 590 600 610 620 630
pF1KA1 NNLGTNSLNKQHNILT--YGNTKPLTHFNADLSQRMTPPV-ANPNKNPLMPYIQQQQQQQ
..:. . .:. : . :::::: :::.: .... : : . :: :. : :::::::
XP_011 QDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQ
310 320 330 340 350 360
640 650 660 670 680
pF1KA1 QQQQQQQQQQQPPPPQLQAPR----------AHLSEDQKRLL----LMKQKGVMNQPMAY
::::::::::: : : . :. ...:. . ..:. ..: .
XP_011 QQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQ
370 380 390 400 410 420
690 700 710
pF1KA1 AALPSHGQEQHPVGLPRTTGPMQ----SSVP-------------PGSG------------
.. :.:.: . : . : : : .: : .:
XP_011 QQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQD
430 440 450 460 470 480
720 730 740 750
pF1KA1 -----GMVSGASPA---------GPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQ
:. .: ::. : :...:: ....:.:. .. : :.: . ::
XP_011 QHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQ--QSLLNQQLMGKKQTL---QRQ--IMEQ
490 500 510 520 530
760 770 780 790 800
pF1KA1 RQQQQQQQQILA--EQQLQQSHLPRQHLQP-------QRNPYPVQQVNQFQGSPQDIAAV
.:: :::.:: :. :... :. .: .:: .: . :..:. . :.
XP_011 KQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLN
540 550 560 570 580 590
810 820 830 840 850 860
pF1KA1 RSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYNM
.:: . . : ... :..... . . ...::. ..::. :.. : .::. :..
XP_011 SNQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTAV--QNMGM--YGNLPCNQPNTYSV
600 610 620 630 640 650
870 880 890 900 910 920
pF1KA1 STGMTQMLQHPNQSGMSITHNQAQGPRQPASG-QGVGMVSGFGQSMLVNSAITQQHPQMK
..::.:. :. : . . ..:. . :: :. : .. . :. :: . . :: : .:..
XP_011 TSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAGSVGNS--QQLRPNLT
660 670 680 690 700 710
930 940 950 960 970 980
pF1KA1 GPVGQALPRPQAPPRLQSLMGTVQQGAQSWQQR---SLQGMPGRTSGELGPFNNGASY-P
.. ..: : : ...: : . : .: .. : : ..: : .. :.: :
XP_011 HSMA-SMP----PQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPTGTPAAYTP
720 730 740 750 760
990 1000 1010 1020
pF1KA1 LQAGQPRLTKQHFPQ-------------------GLSQSVVDANTGTVRTLN--PAAMGR
:. : . .:.: : .::.. . : .: :: : ..
XP_011 NQSLQQAVGSQQFSQRAVAPPNQLTPAVQMRPMNQMSQTLNGQTMGPLRGLNLRPNQLST
770 780 790 800 810 820
1030 1040 1050 1060 1070 1080
pF1KA1 QMMPSLPGQQGTSQARPMVMSGLSQGVPGMPAFSQHPAQQQIPSGSFAPSSQSQAYE-RN
:..:.: .:.:: ::.:. :. .: :. ::. .:...:.:.. .
XP_011 QILPNL-NQSGT---------GLNQSRTGI---NQPPSLT--PSNFPSPNQSSRAFQGTD
830 840 850 860 870
1090 1100 1110 1120 1130
pF1KA1 APQDVSYNYSGDGAGGSFPGLPDGADLVDSIIKGGPGDEWMQELDELFGNP
.:..... .. . :.:
XP_011 HSSDLAFDFLSQQNDNMGPALNSDADFIDSLLKTEPGNDDWMKDINLDEILGNNS
880 890 900 910 920
>>XP_011527029 (OMIM: 605299) PREDICTED: nuclear recepto (2056 aa)
initn: 499 init1: 201 opt: 490 Z-score: 225.2 bits: 54.4 E(85289): 8.4e-06
Smith-Waterman score: 498; 25.8% identity (49.7% similar) in 764 aa overlap (378-1109:166-873)
350 360 370 380 390 400
pF1KA1 TPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTAT-SLPSVASTPAAPNP
: .::: . .. . :... : . :
XP_011 NLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIFFLGIIRMNNPATVMIPPGGNV
140 150 160 170 180 190
410 420 430 440 450 460
pF1KA1 ASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAE
.:: . .:. : .:: : . ::. . . :: .: : :.:.
XP_011 SSS---MMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVS
200 210 220 230 240 250
470 480 490 500 510 520
pF1KA1 QLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGA
.:: . . .:.::.::::::::::::::::::::: . . . :..
XP_011 VNRQM--NPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQG-IRP
260 270 280 290 300
530 540 550 560 570
pF1KA1 AFTA--EKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNY-----LPQNHMNMINQQPN
::: . : : . .: :: ..: : :. :: ..... .:.
XP_011 QFTAPTQVPVPPGWNQLPSGALQP--PPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPS
310 320 330 340 350 360
580 590 600 610 620 630
pF1KA1 NLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNK--NPLMPYIQQQQQQQQQ
:.: . . .: : :. .:. .. : ..::.. : : .: ..
XP_011 -LATVQ-TPSHPPPPY----PFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPT
370 380 390 400 410 420
640 650 660 670 680 690
pF1KA1 QQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLP
:: . . : . . . : .. . . :. . .: :: .: .: ::. :
XP_011 PLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLP-QGFQQ-PVSSP
430 440 450 460 470
700 710 720 730 740 750
pF1KA1 RTTGPM--QSSVPPGSGGMVSGASPAGPGFL----GSQPQAAIMKQMLIDQRAQLI-EQQ
.:: :..:::. : . :: : :.: . .:. .. . : ..
XP_011 -GRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGQANPNFMQGQVPSTTATTPGNSG
480 490 500 510 520 530
760 770 780 790 800
pF1KA1 KQQFLREQRQQQQQQQQILAEQ-QLQQSHLPRQHLQPQRNPYPVQQVNQFQGS---PQDI
:. .: :. : : :.: :: : . .::. .. :: :. :: .
XP_011 APQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQ-V
540 550 560 570 580 590
810 820 830 840 850 860
pF1KA1 AAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGM
:. :. :.::... .. ::: : :. :.. : : . :. .
XP_011 NLSNMQGQPQQGPPSQLMGMHQQIV---PSQ--GQMV----QQQGTLNPQNPMILSRAQL
600 610 620 630 640
870 880 890 900 910 920
pF1KA1 YNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQQHPQ
: : ::. .: ..... . .. :.: : :: :.. : :
XP_011 --MPQG--QMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMA--------------PHNQ
650 660 670 680 690
930 940 950 960 970 980
pF1KA1 MKGPVGQALPRPQAPPRLQSLMGTVQQGAQSWQQRSLQG----MPGRTSGELGPFNNGAS
: :: ::.: : : ....: . .:: . :: . :. ::: .. :: : .
XP_011 MMGPQGQVL--LQQNPMIEQIMTNQMQGNK--QQFNTQNQSNVMPGPAQIMRGPTPNMQG
700 710 720 730 740
990 1000 1010 1020 1030
pF1KA1 YPLQ-AGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMPS--LPGQQGTSQAR
.: .:: .. : .:: :. :. . . : .. .. : :: . :.: .
XP_011 NMVQFTGQ--MSGQMLPQ---QGPVNNSPSQVMGIQGQVL-RPPGPSPHMAQQHGDPATT
750 760 770 780 790 800
1040 1050 1060 1070 1080 1090
pF1KA1 PMVMSGLSQGVP--GMPAFSQHPAQQQIPSGSFAPSSQ--SQAYERNAPQDVSYNYSGDG
.::: .: .. .. : . : .:. : ... .... ::: . . : ...
XP_011 ANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPN-GNQM
810 820 830 840 850
1100 1110 1120 1130
pF1KA1 AGGSFPGLPDGADLVDSIIKGGPGDEWMQELDELFGNP
. :. ::.: . :.
XP_011 SCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNS
860 870 880 890 900 910
>>XP_011541325 (OMIM: 607537) PREDICTED: mastermind-like (1009 aa)
initn: 1433 init1: 223 opt: 479 Z-score: 224.9 bits: 53.3 E(85289): 8.7e-06
Smith-Waterman score: 912; 27.9% identity (53.6% similar) in 1061 aa overlap (157-1103:25-975)
130 140 150 160 170 180
pF1KA1 AGTGKQQHPSKPQQDAEAASAEQRNHTLIMLQETVKRKLEGARSPLNGDQQNGACDGNFS
:: ..::: :: :. . :: :..:
XP_011 MLCESEHQAMIFLCSPKSLQFPQNLQGSLKRKQVVNLSPANSKRPNGFVDNSFL
10 20 30 40 50
190 200 210 220 230 240
pF1KA1 PTSKRIR--KDISAGMEA--INNLPSNMPLPSASPLHQLDLKPSLPLQNSGTHTPGLLED
:::: ...:::. . ::: :.. . .. :. : :. . : : ::.:: .
XP_011 DI-KRIRVGENLSAGQGGLQINNGQSQI-MSGTLPMSQAPLRKTNTLP-SHTHSPG--NG
60 70 80 90 100
250 260 270 280 290
pF1KA1 LSKNGRLPEIKLPVN---GCSDLEDSFTILQSKDLKQEPLDDP--TCIDTSETSLSNQNK
: . : : :.: . .:: :. . : . . .. ::: .: : :.
XP_011 LFNMG-LKEVKKEPGETLSCSKHMDG-QMTQENIFPNRYGDDPGEQLMDPELQELFNELT
110 120 130 140 150 160
300 310 320 330 340 350
pF1KA1 LFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPATETP-LSQESAS
.: ..: : ...:. :. .:: :: :. .. :: .: : : .:.
XP_011 NISVPPMSDLELENMINA---TIKQDDP---FNIDLGQQ-----SQRSTPRPSLPMEKIV
170 180 190 200 210
360 370 380 390 400 410
pF1KA1 VKSDPSHSP-FAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAV
.::. .:: ... :::: :: :.:: :: ...: : .:::
XP_011 IKSE--YSPGLTQGPSGSPQLRPPSAGPAFSMANSALS-------------TSSPI----
220 230 240 250
420 430 440 450 460 470
pF1KA1 QSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPS-SDMSPAEQLKQMAAQ
:..:.. :: :. :.: :: :.:: ...: :.::::.::.
XP_011 --PSVPQS-----QAQPQTGSG-------------AS--RALPSWQEVSHAQQLKQIAAN
260 270 280 290
480 490 500 510 520 530
pF1KA1 QQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPN
.::.:.. ::.:::: : .::: : ..: . : ::
XP_011 RQQHARM-------------------QQHQQQH--QPTNWSALPSSAGPSPGPFGQEKIP
300 310 320 330
540 550 560 570 580
pF1KA1 SPMMYPQAFNNQNPIVPPMANNL-QKTTMNNYL----PQ---NHMNMINQQ-PNNLGTNS
:: . :.:. :. .: .:.. :. .: ::. :. .:.... :: :..:. .
XP_011 SPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSF
340 350 360 370 380 390
590 600 610 620 630 640
pF1KA1 LNKQHNILT--YGNTKPLTHFNADLSQRMTPPV-ANPNKNPLMPYIQQQQQQQQQQQQQQ
.:. : . :::::: :::.: .... : : . :: :. : ::::::::::::::
XP_011 INNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQ
400 410 420 430 440 450
650 660 670 680
pF1KA1 QQQQPPPPQLQAPR----------AHLSEDQKRLL----LMKQKGVMNQPMAYAALPSHG
:::: : : . :. ...:. . ..:. ..: . ..
XP_011 QQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQ
460 470 480 490 500 510
690 700 710
pF1KA1 QEQHPVGLPRTTGPMQ----SSVP-------------PGSG-----------------GM
:.:.: . : . : : : .: : .: :.
XP_011 QQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQ
520 530 540 550 560 570
720 730 740 750 760
pF1KA1 VSGASPA---------GPGFLGSQPQAAIMKQMLIDQRAQL---IEQQKQQFLREQRQQQ
.: ::. : :...:: ....:.:. .. : : .::::.: .: :.
XP_011 NTGPSPSPNPCSNPNTGSGYMNSQQ--SLLNQQLMGKKQTLQRQIMEQKQQLLLQQ-QML
580 590 600 610 620 630
770 780 790 800 810
pF1KA1 QQQQQILAEQQLQQSHL---PRQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQSMR
. ..: ..:... :: : .. . .:: .: . :..:. . :. .:: . .
XP_011 ADAEKIAPQDQINR-HLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVS
640 650 660 670 680 690
820 830 840 850 860 870
pF1KA1 TSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQH
: ... :..... . . ...::. ..::. :.. : .::. :....::.:. :.
XP_011 THTILTPNSSLLSTSHGTRMPSLSTAV--QNMGM--YGNLPCNQPNTYSVTSGMNQLTQQ
700 710 720 730 740
880 890 900 910 920 930
pF1KA1 PNQSGMSITHNQAQGPRQPASG-QGVGMVSGFGQSMLVNSAITQQHPQMKGPVGQALPRP
: . . ..:. . :: :. : .. . :. :: . . :: : .:.. .. ..:
XP_011 RNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQ--QLRPNLTHSMA-SMP--
750 760 770 780 790 800
940 950 960 970 980 990
pF1KA1 QAPPRLQSLMGTVQQGAQSWQQR---SLQGMPGRTSGELGPFNNGASY-PLQAGQPRLTK
: : ...: : . : .: .. : : ..: : .. :.: : :. : . .
XP_011 --PQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGS
810 820 830 840 850
1000 1010 1020 1030
pF1KA1 QHFPQ-------------------GLSQSVVDANTGTVRTLN--PAAMGRQMMPSLPGQQ
:.: : .::.. . : .: :: : .. :..:.: .:.
XP_011 QQFSQRAVAPPNQLTPAVQMRPMNQMSQTLNGQTMGPLRGLNLRPNQLSTQILPNL-NQS
860 870 880 890 900 910
1040 1050 1060 1070 1080 1090
pF1KA1 GTSQARPMVMSGLSQGVPGMPAFSQHPAQQQIPSGSFAPSSQSQAYE-RNAPQDVSYNYS
:: ::.:. :. .: :. ::. .:...:.:.. . .:.....
XP_011 GT---------GLNQSRTGI---NQPPSLT--PSNFPSPNQSSRAFQGTDHSSDLAFDFL
920 930 940 950 960
1100 1110 1120 1130
pF1KA1 GDGAGGSFPGLPDGADLVDSIIKGGPGDEWMQELDELFGNP
.. . :.:
XP_011 SQQNDNMGPALNSDADFIDSLLKTEPGNDDWMKDINLDEILGNNS
970 980 990 1000
>>XP_011527028 (OMIM: 605299) PREDICTED: nuclear recepto (2057 aa)
initn: 499 init1: 201 opt: 486 Z-score: 223.5 bits: 54.1 E(85289): 1e-05
Smith-Waterman score: 496; 26.0% identity (49.4% similar) in 786 aa overlap (378-1109:166-874)
350 360 370 380 390 400
pF1KA1 TPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTAT-SLPSVASTPAAPNP
: .::: . .. . :... : . :
XP_011 NLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIFFLGIIRMNNPATVMIPPGGNV
140 150 160 170 180 190
410 420 430 440 450 460
pF1KA1 ASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAE
.:: . .:. : .:: : . ::. . . :: .: : :.:.
XP_011 SSS---MMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVS
200 210 220 230 240 250
470 480 490 500 510
pF1KA1 QLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQ------QQHSNQT-SNWSP--L
.:: . . . .::.::::::::::::::::::: :::..: .. :
XP_011 VNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFT
260 270 280 290 300 310
520 530 540 550 560
pF1KA1 GPPSSPYGAAFTAEKPNSPMMYPQA-------FNNQN----PIVPPMANNLQ-KTTMNNY
.: . : ... . :.. .. : : ::. :. :: ..:: . .. .
XP_011 APTQVPVPPGWN-QLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATV
320 330 340 350 360 370
570 580 590 600 610
pF1KA1 LPQNHMNMINQQPNNLGTNSLNKQH-NILTYGN----TKPLTHFNADLSQRMTPPVANP-
.: : .:... .. : :. ..: : : . .:. :. .:
XP_011 QTPSH----PPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPH
380 390 400 410 420
620 630 640 650 660
pF1KA1 --NKNPLM-PYIQQQQQQQQQQ--QQQQQQQQPPPPQ-------LQAPRAHLSEDQKRLL
::.: : :: . .. .: :::. : ::: .: : . ...
XP_011 LTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNP----
430 440 450 460 470 480
670 680 690 700 710 720
pF1KA1 LMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLG
: :.: : : . .. :.: : . ::. :. :: : :. :.:.:.
XP_011 -MVQQG--NVPPNFMVM----QQQPP-----NQGPQ--SLHPGLG-----AGQANPNFMQ
490 500 510 520
730 740 750 760 770 780
pF1KA1 SQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLPRQHLQPQ
.: .. . :: .:. : : :.: .: :: : . .::.
XP_011 GQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQ-------MQVSHGPPNMMQPS
530 540 550 560 570
790 800 810 820 830 840
pF1KA1 RNPYPVQQVNQFQGS---PQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMAT
.. :: :. :: . :. :. :.::... .. ::: : :.
XP_011 LMGIHGNMNNQQAGTSGVPQ-VNLSNMQGQPQQGPPSQLMGMHQQIV---PSQ--GQMV-
580 590 600 610 620 630
850 860 870 880 890 900
pF1KA1 AAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQGV
:.. : : . :. . : : ::. .: ..... . .. :.: : ::
XP_011 ---QQQGTLNPQNPMILSRAQL--MPQG--QMMVNPPSQNLGPSPQRMTPPKQMLSQQGP
640 650 660 670 680
910 920 930 940 950 960
pF1KA1 GMVSGFGQSMLVNSAITQQHPQMKGPVGQALPRPQAPPRLQSLMGTVQQGAQSWQQRSLQ
:.. : :: :: ::.: : : ....: . .:: . :: . :
XP_011 QMMA--------------PHNQMMGPQGQVL--LQQNPMIEQIMTNQMQGNK--QQFNTQ
690 700 710 720
970 980 990 1000 1010
pF1KA1 G----MPGRTSGELGPFNNGASYPLQ-AGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPA
. ::: .. :: : . .: .:: .. : .:: :. :. . . : ..
XP_011 NQSNVMPGPAQIMRGPTPNMQGNMVQFTGQ--MSGQMLPQ---QGPVNNSPSQVMGIQGQ
730 740 750 760 770 780
1020 1030 1040 1050 1060 1070
pF1KA1 AMGRQMMPS--LPGQQGTSQARPMVMSGLSQGVP--GMPAFSQHPAQQQIPSGSFAPSSQ
.. : :: . :.: . .::: .: .. .. : . : .:. : ...
XP_011 VL-RPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNH
790 800 810 820 830
1080 1090 1100 1110 1120 1130
pF1KA1 --SQAYERNAPQDVSYNYSGDGAGGSFPGLPDGADLVDSIIKGGPGDEWMQELDELFGNP
.... ::: . . : ... . :. ::.: . :.
XP_011 FSGHGMSFNAPFSGAPN-GNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNN
840 850 860 870 880 890
XP_011 KQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLP
900 910 920 930 940 950
>>XP_016883239 (OMIM: 605299) PREDICTED: nuclear recepto (1094 aa)
initn: 499 init1: 201 opt: 443 Z-score: 209.1 bits: 50.5 E(85289): 6.6e-05
Smith-Waterman score: 482; 25.6% identity (49.2% similar) in 801 aa overlap (378-1109:166-904)
350 360 370 380 390 400
pF1KA1 TPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTAT-SLPSVASTPAAPNP
: .::: . .. . :... : . :
XP_016 NLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIFFLGIIRMNNPATVMIPPGGNV
140 150 160 170 180 190
410 420 430 440 450 460
pF1KA1 ASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAE
.:: . .:. : .:: : . ::. . . :: .: : :.:.
XP_016 SSS---MMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVS
200 210 220 230 240 250
470 480 490 500 510
pF1KA1 QLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQ------QQHSNQT-SNWSP--L
.:: . . . .::.::::::::::::::::::: :::..: .. :
XP_016 VNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFT
260 270 280 290 300 310
520 530 540 550 560
pF1KA1 GPPSSPYGAAFTAEKPNSPMMYPQA-------FNNQN----PIVPPMANNLQ-KTTMNNY
.: . : ... . :.. .. : : ::. :. :: ..:: . .. .
XP_016 APTQVPVPPGWN-QLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATV
320 330 340 350 360 370
570 580 590 600 610
pF1KA1 LPQNHMNMINQQPNNLGTNSLNKQH-NILTYGN----TKPLTHFNADLSQRMTPPVANP-
.: : .:... .. : :. ..: : : . .:. :. .:
XP_016 QTPSH----PPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPH
380 390 400 410 420
620 630 640 650 660
pF1KA1 --NKNPLM-PYIQQQQQQQQQQ--QQQQQQQQPPPPQ-------LQAPRAHLSEDQKRLL
::.: : :: . .. .: :::. : ::: .: : . ...
XP_016 LTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNP----
430 440 450 460 470 480
670 680 690 700 710
pF1KA1 LMKQKGVMNQPMAYAAL----PSHG-QEQHPVGLPRTTGPMQSSV--PPGS--------G
: :.: : : . .. :..: : :: :: . . : . .: : . .
XP_016 -MVQQG--NVPPNFMVMQQQPPNQGPQSLHP-GLGEKSEPSNLAVAWPQITFREQIAIFS
490 500 510 520 530
720 730 740 750 760 770
pF1KA1 GMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQ
: .. :.:.:. .: .. . :: .:. : : :.:
XP_016 LACSKSGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQ------
540 550 560 570 580 590
780 790 800 810 820
pF1KA1 QLQQSHLPRQHLQPQRNPYPVQQVNQFQGS---PQDIAAVRSQAALQSMRTSRLMAQNAG
.: :: : . .::. .. :: :. :: . :. :. :.::...
XP_016 -MQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQ-VNLSNMQGQPQQGPPSQLMGMHQQ
600 610 620 630 640 650
830 840 850 860 870 880
pF1KA1 MMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITH
.. ::: : :. :.. : : . :. . : : ::. .: ..... .
XP_016 IV---PSQ--GQMV----QQQGTLNPQNPMILSRAQL--MPQG--QMMVNPPSQNLGPSP
660 670 680 690
890 900 910 920 930 940
pF1KA1 NQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQQHPQMKGPVGQALPRPQAPPRLQSLMG
.. :.: : :: :.. : :: :: ::.: : : ....:
XP_016 QRMTPPKQMLSQQGPQMMA--------------PHNQMMGPQGQVL--LQQNPMIEQIMT
700 710 720 730 740
950 960 970 980 990 1000
pF1KA1 TVQQGAQSWQQRSLQG----MPGRTSGELGPFNNGASYPLQ-AGQPRLTKQHFPQGLSQS
. .:: . :: . :. ::: .. :: : . .: .:: .. : .:: :.
XP_016 NQMQGNK--QQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQ--MSGQMLPQ---QG
750 760 770 780 790
1010 1020 1030 1040 1050 1060
pF1KA1 VVDANTGTVRTLNPAAMGRQMMPS--LPGQQGTSQARPMVMSGLSQGVP--GMPAFSQHP
:. . . : .. .. : :: . :.: . .::: .: .. .. :
XP_016 PVNNSPSQVMGIQGQVL-RPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVP
800 810 820 830 840 850
1070 1080 1090 1100 1110
pF1KA1 AQQQIPSGSFAPSSQ--SQAYERNAPQDVSYNYSGDGAGGSFPGLPDGADLVDSIIKGGP
. : .:. : ... .... ::: . . : ... . :. ::.: . :.
XP_016 PHVQAMQGNSASGNHFSGHGMSFNAPFSGAPN-GNQMSCGQNPGFPVNKDVTLTSPLLVN
860 870 880 890 900 910
1120 1130
pF1KA1 GDEWMQELDELFGNP
XP_016 LLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLP
920 930 940 950 960 970
1133 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 01:51:17 2016 done: Fri Nov 4 01:51:19 2016
Total Scan time: 14.520 Total Display time: 0.320
Function used was FASTA [36.3.4 Apr, 2011]