FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1849, 1073 aa 1>>>pF1KA1849 1073 - 1073 aa - 1073 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.2373+/-0.00104; mu= 0.4986+/- 0.062 mean_var=315.1989+/-64.803, 0's: 0 Z-trim(114.0): 50 B-trim: 128 in 1/51 Lambda= 0.072241 statistics sampled from 14548 (14589) to 14548 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.764), E-opt: 0.2 (0.448), width: 16 Scan time: 4.600 The best scores are: opt bits E(32554) CCDS43544.1 RADIL gene_id:55698|Hs108|chr7 (1075) 7115 756.2 8.8e-218 CCDS12731.1 RASIP1 gene_id:54922|Hs108|chr19 ( 963) 1266 146.5 2.6e-34 >>CCDS43544.1 RADIL gene_id:55698|Hs108|chr7 (1075 aa) initn: 7126 init1: 5430 opt: 7115 Z-score: 4023.3 bits: 756.2 E(32554): 8.8e-218 Smith-Waterman score: 7115; 98.3% identity (98.7% similar) in 1075 aa overlap (1-1073:1-1075) 10 20 30 40 50 60 pF1KA1 MFYGTHFIMSPPTKSKLKRQSQLLSSMLSRTLSYKYRDLDSTFSSLGASDDPAELSTQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MFYGTHFIMSPPTKSKLKRQSQLLSSMLSRTLSYKYRDLDSTFSSLGASDDPAELSTQLS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 APGVLKVFGDSVCTGTHYKSVLATGTSSARELVKEALERYALDPRQAGQYVLCDVVGQAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 APGVLKVFGDSVCTGTHYKSVLATGTSSARELVKEALERYALDPRQAGQYVLCDVVGQAG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 DAGQRWQARCFRVFGDSEKPLLIQELWKPREGLSRRFELRKRSDVEELAAKEVDTITAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DAGQRWQARCFRVFGDSEKPLLIQELWKPREGLSRRFELRKRSDVEELAAKEVDTITAGI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 NAQARRLQRSRAKGTPTPALGDARSSPPPRLRRTVSETSLSPVNALPAAAQGPEEPGPNA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.: CCDS43 NAQARRLQRSRAKGTPTPALGDARSSPPPRLRRTVSETSLSPVNALPAAAQGPEEPGPDA 190 200 210 220 230 240 250 260 270 280 290 pF1KA1 MRYSLYQSPHLLLLQGYSQQHPG-VCAQPGPAHG-GPADPSSKPSISLSAPDILPLHCTI ::::::::::::::::::::: . : . : : ::::::::::::::::::::: CCDS43 MRYSLYQSPHLLLLQGYSQQHDSLVYVLNRDRHTVGQRTPSSKPSISLSAPDILPLHCTI 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA1 RRQPLPDSGQAAGRLVLEPIPGAHISVNFSEVGHRTVVLHHGDLLSLGLYYLLLFKDPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 RRQPLPDSGQAAGRLVLEPIPGAHISVNFSEVGHRTVVLHHGDLLSLGLYYLLLFKDPAQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA1 AQPLPARALARLRAVPQSCRLCGAALGARGAASPTQAALPRRQQLLLEFEPDLEDTLLQR ::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::: CCDS43 AQPLPARALARLRAVPQSCRLCGAALGARGAASPTQAALPRRQQLLLEFEPHLEDTLLQR 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA1 IMTLIEPGGDDHKLTPAFLLCLCIQHSATHFQPGTFGQLLLKIARLIRETVWEKTKELAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 IMTLIEPGGDDHKLTPAFLLCLCIQHSATHFQPGTFGQLLLKIARLIRETVWEKTKELAE 430 440 450 460 470 480 480 490 500 510 520 530 pF1KA1 KQAQLQEPISLASCAMADLVPDLQPILFWMSNSIELLYFIQQKCPLYMQSMEEQLDITGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 KQAQLQEPISLASCAMADLVPDLQPILFWMSNSIELLYFIQQKCPLYMQSMEEQLDITGS 490 500 510 520 530 540 540 550 560 570 580 590 pF1KA1 KESLFSCTLTASEEAMAVLEEVVLYAFQQCVYYVSKSLYICLPALLECPPFQTERRESWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 KESLFSCTLTASEEAMAVLEEVVLYAFQQCVYYVSKSLYICLPALLECPPFQTERRESWS 550 560 570 580 590 600 600 610 620 630 640 650 pF1KA1 SAPELPEELRRVVSVYQAALDLLRQLQVHPEVASQMLAYLFFFSGTLLLNQLLDRGPSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SAPELPEELRRVVSVYQAALDLLRQLQVHPEVASQMLAYLFFFSGTLLLNQLLDRGPSLS 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA1 CFHWPRGVQACARLQQLLEWMRSAGFGAAGEHFFQKLSCTLNLLATPRAQLIQMSWTALR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 CFHWPRGVQACARLQQLLEWMRSAGFGAAGEHFFQKLSCTLNLLATPRAQLIQMSWTALR 670 680 690 700 710 720 720 730 740 750 760 770 pF1KA1 AAFPALSPAQLHRLLTHYQLASAMGPMSTWEPGAQDSPEAFRSEDVLESYENPPPIVLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 AAFPALSPAQLHRLLTHYQLASAMGPMSTWEPGAQDSPEAFRSEDVLESYENPPPIVLPS 730 740 750 760 770 780 780 790 800 810 820 830 pF1KA1 DGFQVDLEANCLDDSIYQHLLYVRHFLWGLRSRASPGSPGRPGSGASQPVCPEGMHHVVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DGFQVDLEANCLDDSIYQHLLYVRHFLWGLRSRASPGSPGRPGSGASQPVCPEGMHHVVL 790 800 810 820 830 840 840 850 860 870 880 890 pF1KA1 DGHLEAPSCPLAPRDPGPAAREVAPERTLPLRGAPWAQAPPGRQPGRGGSQAGPPHTDSS :::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::: CCDS43 DGHLEAPSCPLAPRDPGPAAREVAPERTLPLRGAPWAQAPPGRQPSRGGSQAGPPHTDSS 850 860 870 880 890 900 900 910 920 930 940 950 pF1KA1 CLLTPPSTPLGPEPGDPDWPESGGPCGKALPERQRNGLSGLRGAAPEGDSAALAEESPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 CLLTPPSTPLGPEPGDPDWPESGGPCGKALPERQRNGLSGLRGAAPEGDSAALAEESPPA 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KA1 PSSRSSSTEDFCYVFTVELERGPSGLGMGLIDGMHTHLGAPGLYIQTLLPGSPAAADGRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 PSSRSSSTEDFCYVFTVELERGPSGLGMGLIDGMHTHLGAPGLYIQTLLPGSPAAADGRL 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KA1 SLGDRILEVNGSSLLGLGYLRAVDLIRHGGKKMRFLVAKSDVETAKKIHFRTPPL ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SLGDRILEVNGSSLLGLGYLRAVDLIRHGGKKMRFLVAKSDVETAKKIHFRTPPL 1030 1040 1050 1060 1070 >>CCDS12731.1 RASIP1 gene_id:54922|Hs108|chr19 (963 aa) initn: 1497 init1: 493 opt: 1266 Z-score: 729.4 bits: 146.5 E(32554): 2.6e-34 Smith-Waterman score: 1651; 37.1% identity (63.3% similar) in 856 aa overlap (47-827:130-963) 20 30 40 50 60 70 pF1KA1 LKRQSQLLSSMLSRTLSYKYRDLDSTFSSLGASDDPAELSTQLSAPGVLKVFGDSVCTGT :.. .: . . :::::.:: .. .:. CCDS12 TTGSSGAGGPGTPGGAQRWASEKKLPELAAGVAPEPPLATRATAPPGVLKIFGAGLASGA 100 110 120 130 140 150 80 90 100 110 120 pF1KA1 HYKSVLATGTSSARELVKEALERYALDPRQAG---------QYVLCDVVGQAGDAG---Q .:::::::. :.::::: ::::::.: .: ..:::..:. . :: CCDS12 NYKSVLATARSTARELVAEALERYGLAGSPGGGPGESSCVDAFALCDALGRPAAAGVGSG 160 170 180 190 200 210 130 140 150 160 170 180 pF1KA1 RWQARCFRVFGDSEKPLLIQELWKPREGLSRRFELRKRSDVEELAAKEVDTI-TAGINAQ .:.:. .::.::::.:::.::::. : : .:::::: : ....: . . . : .: CCDS12 EWRAEHLRVLGDSERPLLVQELWRARPGWARRFELRGREEARRLEQEAFGAADSEGTGAP 220 230 240 250 260 270 190 200 210 220 pF1KA1 ARRLQRSRAKG--------TPTPALGD---ARSSPPPR-----LRRTVSETSLS------ . : :..:... .: :. :. : :. : :::.::: ::. CCDS12 SWRPQKNRSRAASGGAALASPGPGTGSGAPAGSGGKERSENLSLRRSVSELSLQGRRRRQ 280 290 300 310 320 330 230 240 250 pF1KA1 ------PVNALPAAAQ---GPEEPGP-NAMRYSLYQSP----HLLLLQGYS--------- .. :.::. : .:: . . : :.: ..::::::. CCDS12 QERRQQALSMAPGAADAQIGTADPGDFDQLTQCLIQAPSNRPYFLLLQGYQDAQDFVVYV 340 350 360 370 380 390 260 270 280 290 300 310 pF1KA1 ---QQHPGVCAQPGPAHGGPADPSSKPSISLSAPDILPLHCTIRRQPLPDSGQAAGRLVL .:: : .. : . : ..:. . :.:::::: :::.: : . .. CCDS12 MTREQH--VFGRGGNSSGRGGSPAPYVDTFLNAPDILPRHCTVRAGPEHPA-------MV 400 410 420 430 440 450 320 330 340 350 360 370 pF1KA1 EPIPGAHISVNFSEVGHRTVVLHHGDLLSLGLYYLLLFKDPAQAQPLPARAL---ARLRA .: :: .. : . . : . :: ::::.:: ..:...::: . ::: :: : CCDS12 RPSRGAPVTHN-GCLLLREAELHPGDLLGLGEHFLFMYKDPRTGGSGPARPPWLPARPGA 460 470 480 490 500 380 390 400 410 420 pF1KA1 VPQ------SCRLCGAALGARGAASPTQAALPRRQQLLLEFEPDLEDTLLQRIMTLIEPG .: :::::: .: :: : : : :. .: .:.: :..:: .:. : CCDS12 TPPGPGWAFSCRLCGRGLQERGEA--LAAYLDGREPVL-RFRPREEEALLGEIVRAAAAG 510 520 530 540 550 560 430 440 450 460 470 480 pF1KA1 -GDDHKLTPAFLLCLCIQHSATHFQPGTFGQLLLKIARLIRETVWEKTKELAEKQAQLQ- :: : :: :: ::.:::: ... : . .:: ..::::.:.:::: ::....: . . CCDS12 SGDLPPLGPATLLALCVQHSARELELGHLPRLLGRLARLIKEAVWEKIKEIGDRQPENHP 570 580 590 600 610 620 490 500 510 520 530 540 pF1KA1 EPISLASCAMADLVPDLQPILFWMSNSIELLYFIQQKCPLYMQSMEEQLDITGSKESLFS : . . . . .:.:...::.:. ::: :.:.: . ::.. : ... . CCDS12 EGVPEVPLTPEAVSVELRPLMLWMANTTELLSFVQEK----VLEMEKEAD---QEDPQLC 630 640 650 660 670 550 560 570 580 590 600 pF1KA1 CTLTASEEAMAVLEEVVLYAFQQCVYYVSKSLYICLPALLECPPFQTERRESWSSAPEL- : .::::.:.::.. .::: :::..:.:: :::::. :: : : . . :: CCDS12 NDLELCDEAMALLDEVIMCTFQQSVYYLTKTLYSTLPALLDSNPF-TAGAELPGPGAELG 680 690 700 710 720 730 610 620 630 640 650 660 pF1KA1 --PEELRRVVSVYQAALDLLRQLQVHPEVASQMLAYLFFFSGTLLLNQLLDRGPSLSCFH : :: ...:.::::.: : ..::...:: ..::::::.. :::.:..:: . .. CCDS12 AMPPGLRPTLGVFQAALELTSQCELHPDLVSQTFGYLFFFSNASLLNSLMERGQGRPFYQ 740 750 760 770 780 790 670 680 690 700 710 720 pF1KA1 WPRGVQACARLQQLLEWMRSAGFGAAGEHFFQKLSCTLNLLATPRAQLIQMSWTALRAAF : :.:: . :. .:.:...::.: . .::.::: ..::: .::..:.. ::..::. CCDS12 WSRAVQIRTNLDLVLDWLQGAGLGDIATEFFRKLSMAVNLLCVPRTSLLKASWSSLRTDH 800 810 820 830 840 850 730 740 750 760 770 780 pF1KA1 PALSPAQLHRLLTHYQLASAMGPMSTWEPGAQDSPEAFRSEDVLESYENPPPIVLPSDGF :.:.:::::.::.::::. . :: ..:.: . :: . :..::. . ::..:: . CCDS12 PTLTPAQLHHLLSHYQLGPGRGPPAAWDPPPAER-EAVDTGDIFESFSSHPPLILPLGSS 860 870 880 890 900 910 790 800 810 820 830 840 pF1KA1 QVDLEANCLDDSIYQHLLYVRHFLWGLRSRASPGSPGRPGSGASQPVCPEGMHHVVLDGH .. : . ::.....: .:..:: :... :.. . :..: CCDS12 RLRLTGPVTDDALHRELRRLRRLLWDLEQQELPANYRHGPPVATSP 920 930 940 950 960 850 860 870 880 890 900 pF1KA1 LEAPSCPLAPRDPGPAAREVAPERTLPLRGAPWAQAPPGRQPGRGGSQAGPPHTDSSCLL 1073 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:56:01 2016 done: Sat Nov 5 06:56:02 2016 Total Scan time: 4.600 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]