FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1861, 957 aa 1>>>pF1KA1861 957 - 957 aa - 957 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7336+/-0.00124; mu= 14.2123+/- 0.074 mean_var=87.1789+/-17.497, 0's: 0 Z-trim(102.6): 24 B-trim: 402 in 1/49 Lambda= 0.137363 statistics sampled from 7004 (7012) to 7004 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.565), E-opt: 0.2 (0.215), width: 16 Scan time: 3.220 The best scores are: opt bits E(32554) CCDS43617.1 VPS50 gene_id:55610|Hs108|chr7 ( 964) 6215 1242.5 0 CCDS59065.1 VPS50 gene_id:55610|Hs108|chr7 ( 934) 6044 1208.6 0 CCDS5630.1 VPS50 gene_id:55610|Hs108|chr7 ( 327) 1963 399.8 4.6e-111 >>CCDS43617.1 VPS50 gene_id:55610|Hs108|chr7 (964 aa) initn: 6215 init1: 6215 opt: 6215 Z-score: 6653.5 bits: 1242.5 E(32554): 0 Smith-Waterman score: 6215; 100.0% identity (100.0% similar) in 957 aa overlap (1-957:8-964) 10 20 30 40 50 pF1KA1 MTRQGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQAEQELINSIEQV ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MQKIKSLMTRQGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQAEQELINSIEQV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA1 YFSVDSFDIVKYELEKLPPVLNLQELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 YFSVDSFDIVKYELEKLPPVLNLQELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA1 RVTSLQTGLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 RVTSLQTGLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA1 QRTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 QRTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVA 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA1 LSKICKNFDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LSKICKNFDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNT 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA1 DTKFQKLQYKDLCTHVTPDSYIPCLADLCKALWEVMLSYYRTMEWHEKHDNEDTASASEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DTKFQKLQYKDLCTHVTPDSYIPCLADLCKALWEVMLSYYRTMEWHEKHDNEDTASASEG 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA1 SNMIGTEETNFDRGYIKKKLEHGLTRIWQDVQLKVKTYLLGTDLSIFKYDDFIFVLDIIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SNMIGTEETNFDRGYIKKKLEHGLTRIWQDVQLKVKTYLLGTDLSIFKYDDFIFVLDIIS 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA1 RLMQVGEEFCGSKSEVLQESIRKQSVNYFKNYHRTRLDELRMFLENETWELCPVKSNFSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 RLMQVGEEFCGSKSEVLQESIRKQSVNYFKNYHRTRLDELRMFLENETWELCPVKSNFSI 430 440 450 460 470 480 480 490 500 510 520 530 pF1KA1 LQLHEFKFMEQSRSPSVSPSKQPVSTSSKTVTLFEQYCSGGNPFEIQANHKDEETEDVLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LQLHEFKFMEQSRSPSVSPSKQPVSTSSKTVTLFEQYCSGGNPFEIQANHKDEETEDVLA 490 500 510 520 530 540 540 550 560 570 580 590 pF1KA1 SNGYESDEQEKSAYQEYDSDSDVPEELKRDYVDEQTGDGPVKSVSRETLKSRKKSDYSLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SNGYESDEQEKSAYQEYDSDSDVPEELKRDYVDEQTGDGPVKSVSRETLKSRKKSDYSLN 550 560 570 580 590 600 600 610 620 630 640 650 pF1KA1 KVNAPILTNTTLNVIRLVGKYMQMMNILKPIAFDVIHFMSQLFDYYLYAIYTFFGRNDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 KVNAPILTNTTLNVIRLVGKYMQMMNILKPIAFDVIHFMSQLFDYYLYAIYTFFGRNDSL 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA1 ESTGLGLSSSRLRTTLNRIQESLIDLEVSADPTATLTAAEERKEKVPSPHLSHLVVLTSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 ESTGLGLSSSRLRTTLNRIQESLIDLEVSADPTATLTAAEERKEKVPSPHLSHLVVLTSG 670 680 690 700 710 720 720 730 740 750 760 770 pF1KA1 DTLYGLAERVVATESLVFLAEQFEFLQPHLDAVMPAVKKPFLQQFYSQTVSTASELRKPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DTLYGLAERVVATESLVFLAEQFEFLQPHLDAVMPAVKKPFLQQFYSQTVSTASELRKPI 730 740 750 760 770 780 780 790 800 810 820 830 pF1KA1 YWIVAGKALDYEQMLLLMANVKWDVKEIMSQHNIYVDALLKEFEQFNRRLNEVSKRVRIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 YWIVAGKALDYEQMLLLMANVKWDVKEIMSQHNIYVDALLKEFEQFNRRLNEVSKRVRIP 790 800 810 820 830 840 840 850 860 870 880 890 pF1KA1 LPVSNILWEHCIRLANRTIVEGYANVKKCSNEGRALMQLDFQQFLMKLEKLTDIRPIPDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LPVSNILWEHCIRLANRTIVEGYANVKKCSNEGRALMQLDFQQFLMKLEKLTDIRPIPDK 850 860 870 880 890 900 900 910 920 930 940 950 pF1KA1 EFVETYIKAYYLTENDMERWIKEHREYSTKQLTNLVNVCLGSHINKKARQKLLAAIDDID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 EFVETYIKAYYLTENDMERWIKEHREYSTKQLTNLVNVCLGSHINKKARQKLLAAIDDID 910 920 930 940 950 960 pF1KA1 RPKR :::: CCDS43 RPKR >>CCDS59065.1 VPS50 gene_id:55610|Hs108|chr7 (934 aa) initn: 6044 init1: 6044 opt: 6044 Z-score: 6470.6 bits: 1208.6 E(32554): 0 Smith-Waterman score: 6044; 100.0% identity (100.0% similar) in 930 aa overlap (28-957:5-934) 10 20 30 40 50 60 pF1KA1 MTRQGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQAEQELINSIEQVYFSVDSF ::::::::::::::::::::::::::::::::: CCDS59 MLTLEEFRELREQPSDPQAEQELINSIEQVYFSVDSF 10 20 30 70 80 90 100 110 120 pF1KA1 DIVKYELEKLPPVLNLQELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELERVTSLQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 DIVKYELEKLPPVLNLQELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELERVTSLQT 40 50 60 70 80 90 130 140 150 160 170 180 pF1KA1 GLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTLQRTDVRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 GLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTLQRTDVRL 100 110 120 130 140 150 190 200 210 220 230 240 pF1KA1 SEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVALSKICKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVALSKICKN 160 170 180 190 200 210 250 260 270 280 290 300 pF1KA1 FDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNTDTKFQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 FDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNTDTKFQKL 220 230 240 250 260 270 310 320 330 340 350 360 pF1KA1 QYKDLCTHVTPDSYIPCLADLCKALWEVMLSYYRTMEWHEKHDNEDTASASEGSNMIGTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 QYKDLCTHVTPDSYIPCLADLCKALWEVMLSYYRTMEWHEKHDNEDTASASEGSNMIGTE 280 290 300 310 320 330 370 380 390 400 410 420 pF1KA1 ETNFDRGYIKKKLEHGLTRIWQDVQLKVKTYLLGTDLSIFKYDDFIFVLDIISRLMQVGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 ETNFDRGYIKKKLEHGLTRIWQDVQLKVKTYLLGTDLSIFKYDDFIFVLDIISRLMQVGE 340 350 360 370 380 390 430 440 450 460 470 480 pF1KA1 EFCGSKSEVLQESIRKQSVNYFKNYHRTRLDELRMFLENETWELCPVKSNFSILQLHEFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 EFCGSKSEVLQESIRKQSVNYFKNYHRTRLDELRMFLENETWELCPVKSNFSILQLHEFK 400 410 420 430 440 450 490 500 510 520 530 540 pF1KA1 FMEQSRSPSVSPSKQPVSTSSKTVTLFEQYCSGGNPFEIQANHKDEETEDVLASNGYESD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 FMEQSRSPSVSPSKQPVSTSSKTVTLFEQYCSGGNPFEIQANHKDEETEDVLASNGYESD 460 470 480 490 500 510 550 560 570 580 590 600 pF1KA1 EQEKSAYQEYDSDSDVPEELKRDYVDEQTGDGPVKSVSRETLKSRKKSDYSLNKVNAPIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 EQEKSAYQEYDSDSDVPEELKRDYVDEQTGDGPVKSVSRETLKSRKKSDYSLNKVNAPIL 520 530 540 550 560 570 610 620 630 640 650 660 pF1KA1 TNTTLNVIRLVGKYMQMMNILKPIAFDVIHFMSQLFDYYLYAIYTFFGRNDSLESTGLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 TNTTLNVIRLVGKYMQMMNILKPIAFDVIHFMSQLFDYYLYAIYTFFGRNDSLESTGLGL 580 590 600 610 620 630 670 680 690 700 710 720 pF1KA1 SSSRLRTTLNRIQESLIDLEVSADPTATLTAAEERKEKVPSPHLSHLVVLTSGDTLYGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SSSRLRTTLNRIQESLIDLEVSADPTATLTAAEERKEKVPSPHLSHLVVLTSGDTLYGLA 640 650 660 670 680 690 730 740 750 760 770 780 pF1KA1 ERVVATESLVFLAEQFEFLQPHLDAVMPAVKKPFLQQFYSQTVSTASELRKPIYWIVAGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 ERVVATESLVFLAEQFEFLQPHLDAVMPAVKKPFLQQFYSQTVSTASELRKPIYWIVAGK 700 710 720 730 740 750 790 800 810 820 830 840 pF1KA1 ALDYEQMLLLMANVKWDVKEIMSQHNIYVDALLKEFEQFNRRLNEVSKRVRIPLPVSNIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 ALDYEQMLLLMANVKWDVKEIMSQHNIYVDALLKEFEQFNRRLNEVSKRVRIPLPVSNIL 760 770 780 790 800 810 850 860 870 880 890 900 pF1KA1 WEHCIRLANRTIVEGYANVKKCSNEGRALMQLDFQQFLMKLEKLTDIRPIPDKEFVETYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 WEHCIRLANRTIVEGYANVKKCSNEGRALMQLDFQQFLMKLEKLTDIRPIPDKEFVETYI 820 830 840 850 860 870 910 920 930 940 950 pF1KA1 KAYYLTENDMERWIKEHREYSTKQLTNLVNVCLGSHINKKARQKLLAAIDDIDRPKR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 KAYYLTENDMERWIKEHREYSTKQLTNLVNVCLGSHINKKARQKLLAAIDDIDRPKR 880 890 900 910 920 930 >>CCDS5630.1 VPS50 gene_id:55610|Hs108|chr7 (327 aa) initn: 1963 init1: 1963 opt: 1963 Z-score: 2107.4 bits: 399.8 E(32554): 4.6e-111 Smith-Waterman score: 1963; 100.0% identity (100.0% similar) in 307 aa overlap (1-307:8-314) 10 20 30 40 50 pF1KA1 MTRQGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQAEQELINSIEQV ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 MQKIKSLMTRQGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQAEQELINSIEQV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA1 YFSVDSFDIVKYELEKLPPVLNLQELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 YFSVDSFDIVKYELEKLPPVLNLQELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA1 RVTSLQTGLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 RVTSLQTGLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA1 QRTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 QRTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVA 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA1 LSKICKNFDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 LSKICKNFDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNT 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA1 DTKFQKLQYKDLCTHVTPDSYIPCLADLCKALWEVMLSYYRTMEWHEKHDNEDTASASEG :::::::::::::: CCDS56 DTKFQKLQYKDLCTVCSDLITIHISLL 310 320 957 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 22:09:23 2016 done: Wed Nov 2 22:09:24 2016 Total Scan time: 3.220 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]