FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1861, 957 aa 1>>>pF1KA1861 957 - 957 aa - 957 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0510+/-0.000508; mu= 18.5452+/- 0.032 mean_var=100.0909+/-20.479, 0's: 0 Z-trim(109.8): 34 B-trim: 82 in 2/50 Lambda= 0.128197 statistics sampled from 18005 (18016) to 18005 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.562), E-opt: 0.2 (0.211), width: 16 Scan time: 12.370 The best scores are: opt bits E(85289) NP_060137 (OMIM: 616465) syndetin isoform a [Homo ( 964) 6215 1161.2 0 NP_001244927 (OMIM: 616465) syndetin isoform c [Ho ( 934) 6044 1129.6 0 XP_011514697 (OMIM: 616465) PREDICTED: syndetin is ( 775) 5084 952.0 0 XP_011514698 (OMIM: 616465) PREDICTED: syndetin is ( 682) 3971 746.1 1.4e-214 XP_016867901 (OMIM: 616465) PREDICTED: syndetin is ( 576) 3726 700.7 5.4e-201 NP_078829 (OMIM: 616465) syndetin isoform b [Homo ( 327) 1963 374.5 5e-103 >>NP_060137 (OMIM: 616465) syndetin isoform a [Homo sapi (964 aa) initn: 6215 init1: 6215 opt: 6215 Z-score: 6214.2 bits: 1161.2 E(85289): 0 Smith-Waterman score: 6215; 100.0% identity (100.0% similar) in 957 aa overlap (1-957:8-964) 10 20 30 40 50 pF1KA1 MTRQGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQAEQELINSIEQV ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MQKIKSLMTRQGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQAEQELINSIEQV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA1 YFSVDSFDIVKYELEKLPPVLNLQELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 YFSVDSFDIVKYELEKLPPVLNLQELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA1 RVTSLQTGLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 RVTSLQTGLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA1 QRTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 QRTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVA 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA1 LSKICKNFDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 LSKICKNFDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNT 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA1 DTKFQKLQYKDLCTHVTPDSYIPCLADLCKALWEVMLSYYRTMEWHEKHDNEDTASASEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 DTKFQKLQYKDLCTHVTPDSYIPCLADLCKALWEVMLSYYRTMEWHEKHDNEDTASASEG 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA1 SNMIGTEETNFDRGYIKKKLEHGLTRIWQDVQLKVKTYLLGTDLSIFKYDDFIFVLDIIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SNMIGTEETNFDRGYIKKKLEHGLTRIWQDVQLKVKTYLLGTDLSIFKYDDFIFVLDIIS 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA1 RLMQVGEEFCGSKSEVLQESIRKQSVNYFKNYHRTRLDELRMFLENETWELCPVKSNFSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 RLMQVGEEFCGSKSEVLQESIRKQSVNYFKNYHRTRLDELRMFLENETWELCPVKSNFSI 430 440 450 460 470 480 480 490 500 510 520 530 pF1KA1 LQLHEFKFMEQSRSPSVSPSKQPVSTSSKTVTLFEQYCSGGNPFEIQANHKDEETEDVLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 LQLHEFKFMEQSRSPSVSPSKQPVSTSSKTVTLFEQYCSGGNPFEIQANHKDEETEDVLA 490 500 510 520 530 540 540 550 560 570 580 590 pF1KA1 SNGYESDEQEKSAYQEYDSDSDVPEELKRDYVDEQTGDGPVKSVSRETLKSRKKSDYSLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SNGYESDEQEKSAYQEYDSDSDVPEELKRDYVDEQTGDGPVKSVSRETLKSRKKSDYSLN 550 560 570 580 590 600 600 610 620 630 640 650 pF1KA1 KVNAPILTNTTLNVIRLVGKYMQMMNILKPIAFDVIHFMSQLFDYYLYAIYTFFGRNDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 KVNAPILTNTTLNVIRLVGKYMQMMNILKPIAFDVIHFMSQLFDYYLYAIYTFFGRNDSL 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA1 ESTGLGLSSSRLRTTLNRIQESLIDLEVSADPTATLTAAEERKEKVPSPHLSHLVVLTSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 ESTGLGLSSSRLRTTLNRIQESLIDLEVSADPTATLTAAEERKEKVPSPHLSHLVVLTSG 670 680 690 700 710 720 720 730 740 750 760 770 pF1KA1 DTLYGLAERVVATESLVFLAEQFEFLQPHLDAVMPAVKKPFLQQFYSQTVSTASELRKPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 DTLYGLAERVVATESLVFLAEQFEFLQPHLDAVMPAVKKPFLQQFYSQTVSTASELRKPI 730 740 750 760 770 780 780 790 800 810 820 830 pF1KA1 YWIVAGKALDYEQMLLLMANVKWDVKEIMSQHNIYVDALLKEFEQFNRRLNEVSKRVRIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 YWIVAGKALDYEQMLLLMANVKWDVKEIMSQHNIYVDALLKEFEQFNRRLNEVSKRVRIP 790 800 810 820 830 840 840 850 860 870 880 890 pF1KA1 LPVSNILWEHCIRLANRTIVEGYANVKKCSNEGRALMQLDFQQFLMKLEKLTDIRPIPDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 LPVSNILWEHCIRLANRTIVEGYANVKKCSNEGRALMQLDFQQFLMKLEKLTDIRPIPDK 850 860 870 880 890 900 900 910 920 930 940 950 pF1KA1 EFVETYIKAYYLTENDMERWIKEHREYSTKQLTNLVNVCLGSHINKKARQKLLAAIDDID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 EFVETYIKAYYLTENDMERWIKEHREYSTKQLTNLVNVCLGSHINKKARQKLLAAIDDID 910 920 930 940 950 960 pF1KA1 RPKR :::: NP_060 RPKR >>NP_001244927 (OMIM: 616465) syndetin isoform c [Homo s (934 aa) initn: 6044 init1: 6044 opt: 6044 Z-score: 6043.5 bits: 1129.6 E(85289): 0 Smith-Waterman score: 6044; 100.0% identity (100.0% similar) in 930 aa overlap (28-957:5-934) 10 20 30 40 50 60 pF1KA1 MTRQGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQAEQELINSIEQVYFSVDSF ::::::::::::::::::::::::::::::::: NP_001 MLTLEEFRELREQPSDPQAEQELINSIEQVYFSVDSF 10 20 30 70 80 90 100 110 120 pF1KA1 DIVKYELEKLPPVLNLQELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELERVTSLQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DIVKYELEKLPPVLNLQELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELERVTSLQT 40 50 60 70 80 90 130 140 150 160 170 180 pF1KA1 GLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTLQRTDVRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTLQRTDVRL 100 110 120 130 140 150 190 200 210 220 230 240 pF1KA1 SEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVALSKICKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVALSKICKN 160 170 180 190 200 210 250 260 270 280 290 300 pF1KA1 FDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNTDTKFQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNTDTKFQKL 220 230 240 250 260 270 310 320 330 340 350 360 pF1KA1 QYKDLCTHVTPDSYIPCLADLCKALWEVMLSYYRTMEWHEKHDNEDTASASEGSNMIGTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QYKDLCTHVTPDSYIPCLADLCKALWEVMLSYYRTMEWHEKHDNEDTASASEGSNMIGTE 280 290 300 310 320 330 370 380 390 400 410 420 pF1KA1 ETNFDRGYIKKKLEHGLTRIWQDVQLKVKTYLLGTDLSIFKYDDFIFVLDIISRLMQVGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETNFDRGYIKKKLEHGLTRIWQDVQLKVKTYLLGTDLSIFKYDDFIFVLDIISRLMQVGE 340 350 360 370 380 390 430 440 450 460 470 480 pF1KA1 EFCGSKSEVLQESIRKQSVNYFKNYHRTRLDELRMFLENETWELCPVKSNFSILQLHEFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EFCGSKSEVLQESIRKQSVNYFKNYHRTRLDELRMFLENETWELCPVKSNFSILQLHEFK 400 410 420 430 440 450 490 500 510 520 530 540 pF1KA1 FMEQSRSPSVSPSKQPVSTSSKTVTLFEQYCSGGNPFEIQANHKDEETEDVLASNGYESD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FMEQSRSPSVSPSKQPVSTSSKTVTLFEQYCSGGNPFEIQANHKDEETEDVLASNGYESD 460 470 480 490 500 510 550 560 570 580 590 600 pF1KA1 EQEKSAYQEYDSDSDVPEELKRDYVDEQTGDGPVKSVSRETLKSRKKSDYSLNKVNAPIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQEKSAYQEYDSDSDVPEELKRDYVDEQTGDGPVKSVSRETLKSRKKSDYSLNKVNAPIL 520 530 540 550 560 570 610 620 630 640 650 660 pF1KA1 TNTTLNVIRLVGKYMQMMNILKPIAFDVIHFMSQLFDYYLYAIYTFFGRNDSLESTGLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNTTLNVIRLVGKYMQMMNILKPIAFDVIHFMSQLFDYYLYAIYTFFGRNDSLESTGLGL 580 590 600 610 620 630 670 680 690 700 710 720 pF1KA1 SSSRLRTTLNRIQESLIDLEVSADPTATLTAAEERKEKVPSPHLSHLVVLTSGDTLYGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSSRLRTTLNRIQESLIDLEVSADPTATLTAAEERKEKVPSPHLSHLVVLTSGDTLYGLA 640 650 660 670 680 690 730 740 750 760 770 780 pF1KA1 ERVVATESLVFLAEQFEFLQPHLDAVMPAVKKPFLQQFYSQTVSTASELRKPIYWIVAGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERVVATESLVFLAEQFEFLQPHLDAVMPAVKKPFLQQFYSQTVSTASELRKPIYWIVAGK 700 710 720 730 740 750 790 800 810 820 830 840 pF1KA1 ALDYEQMLLLMANVKWDVKEIMSQHNIYVDALLKEFEQFNRRLNEVSKRVRIPLPVSNIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALDYEQMLLLMANVKWDVKEIMSQHNIYVDALLKEFEQFNRRLNEVSKRVRIPLPVSNIL 760 770 780 790 800 810 850 860 870 880 890 900 pF1KA1 WEHCIRLANRTIVEGYANVKKCSNEGRALMQLDFQQFLMKLEKLTDIRPIPDKEFVETYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WEHCIRLANRTIVEGYANVKKCSNEGRALMQLDFQQFLMKLEKLTDIRPIPDKEFVETYI 820 830 840 850 860 870 910 920 930 940 950 pF1KA1 KAYYLTENDMERWIKEHREYSTKQLTNLVNVCLGSHINKKARQKLLAAIDDIDRPKR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KAYYLTENDMERWIKEHREYSTKQLTNLVNVCLGSHINKKARQKLLAAIDDIDRPKR 880 890 900 910 920 930 >>XP_011514697 (OMIM: 616465) PREDICTED: syndetin isofor (775 aa) initn: 5084 init1: 5084 opt: 5084 Z-score: 5085.0 bits: 952.0 E(85289): 0 Smith-Waterman score: 5084; 100.0% identity (100.0% similar) in 775 aa overlap (183-957:1-775) 160 170 180 190 200 210 pF1KA1 NQRKRQLLIGLLKSLRTIKTLQRTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCI :::::::::::::::::::::::::::::: XP_011 MLEEEDYPGAIQLCLECQKAASTFKHYSCI 10 20 30 220 230 240 250 260 270 pF1KA1 SELNSKLQDTLEQIEEQLDVALSKICKNFDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SELNSKLQDTLEQIEEQLDVALSKICKNFDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQ 40 50 60 70 80 90 280 290 300 310 320 330 pF1KA1 AIHNTVFQVVLGYVELCAGNTDTKFQKLQYKDLCTHVTPDSYIPCLADLCKALWEVMLSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AIHNTVFQVVLGYVELCAGNTDTKFQKLQYKDLCTHVTPDSYIPCLADLCKALWEVMLSY 100 110 120 130 140 150 340 350 360 370 380 390 pF1KA1 YRTMEWHEKHDNEDTASASEGSNMIGTEETNFDRGYIKKKLEHGLTRIWQDVQLKVKTYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YRTMEWHEKHDNEDTASASEGSNMIGTEETNFDRGYIKKKLEHGLTRIWQDVQLKVKTYL 160 170 180 190 200 210 400 410 420 430 440 450 pF1KA1 LGTDLSIFKYDDFIFVLDIISRLMQVGEEFCGSKSEVLQESIRKQSVNYFKNYHRTRLDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGTDLSIFKYDDFIFVLDIISRLMQVGEEFCGSKSEVLQESIRKQSVNYFKNYHRTRLDE 220 230 240 250 260 270 460 470 480 490 500 510 pF1KA1 LRMFLENETWELCPVKSNFSILQLHEFKFMEQSRSPSVSPSKQPVSTSSKTVTLFEQYCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRMFLENETWELCPVKSNFSILQLHEFKFMEQSRSPSVSPSKQPVSTSSKTVTLFEQYCS 280 290 300 310 320 330 520 530 540 550 560 570 pF1KA1 GGNPFEIQANHKDEETEDVLASNGYESDEQEKSAYQEYDSDSDVPEELKRDYVDEQTGDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGNPFEIQANHKDEETEDVLASNGYESDEQEKSAYQEYDSDSDVPEELKRDYVDEQTGDG 340 350 360 370 380 390 580 590 600 610 620 630 pF1KA1 PVKSVSRETLKSRKKSDYSLNKVNAPILTNTTLNVIRLVGKYMQMMNILKPIAFDVIHFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVKSVSRETLKSRKKSDYSLNKVNAPILTNTTLNVIRLVGKYMQMMNILKPIAFDVIHFM 400 410 420 430 440 450 640 650 660 670 680 690 pF1KA1 SQLFDYYLYAIYTFFGRNDSLESTGLGLSSSRLRTTLNRIQESLIDLEVSADPTATLTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQLFDYYLYAIYTFFGRNDSLESTGLGLSSSRLRTTLNRIQESLIDLEVSADPTATLTAA 460 470 480 490 500 510 700 710 720 730 740 750 pF1KA1 EERKEKVPSPHLSHLVVLTSGDTLYGLAERVVATESLVFLAEQFEFLQPHLDAVMPAVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EERKEKVPSPHLSHLVVLTSGDTLYGLAERVVATESLVFLAEQFEFLQPHLDAVMPAVKK 520 530 540 550 560 570 760 770 780 790 800 810 pF1KA1 PFLQQFYSQTVSTASELRKPIYWIVAGKALDYEQMLLLMANVKWDVKEIMSQHNIYVDAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PFLQQFYSQTVSTASELRKPIYWIVAGKALDYEQMLLLMANVKWDVKEIMSQHNIYVDAL 580 590 600 610 620 630 820 830 840 850 860 870 pF1KA1 LKEFEQFNRRLNEVSKRVRIPLPVSNILWEHCIRLANRTIVEGYANVKKCSNEGRALMQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKEFEQFNRRLNEVSKRVRIPLPVSNILWEHCIRLANRTIVEGYANVKKCSNEGRALMQL 640 650 660 670 680 690 880 890 900 910 920 930 pF1KA1 DFQQFLMKLEKLTDIRPIPDKEFVETYIKAYYLTENDMERWIKEHREYSTKQLTNLVNVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DFQQFLMKLEKLTDIRPIPDKEFVETYIKAYYLTENDMERWIKEHREYSTKQLTNLVNVC 700 710 720 730 740 750 940 950 pF1KA1 LGSHINKKARQKLLAAIDDIDRPKR ::::::::::::::::::::::::: XP_011 LGSHINKKARQKLLAAIDDIDRPKR 760 770 >>XP_011514698 (OMIM: 616465) PREDICTED: syndetin isofor (682 aa) initn: 3971 init1: 3971 opt: 3971 Z-score: 3973.3 bits: 746.1 E(85289): 1.4e-214 Smith-Waterman score: 3971; 100.0% identity (100.0% similar) in 611 aa overlap (1-611:8-618) 10 20 30 40 50 pF1KA1 MTRQGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQAEQELINSIEQV ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQKIKSLMTRQGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQAEQELINSIEQV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA1 YFSVDSFDIVKYELEKLPPVLNLQELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YFSVDSFDIVKYELEKLPPVLNLQELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA1 RVTSLQTGLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RVTSLQTGLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA1 QRTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVA 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA1 LSKICKNFDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSKICKNFDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNT 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA1 DTKFQKLQYKDLCTHVTPDSYIPCLADLCKALWEVMLSYYRTMEWHEKHDNEDTASASEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTKFQKLQYKDLCTHVTPDSYIPCLADLCKALWEVMLSYYRTMEWHEKHDNEDTASASEG 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA1 SNMIGTEETNFDRGYIKKKLEHGLTRIWQDVQLKVKTYLLGTDLSIFKYDDFIFVLDIIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNMIGTEETNFDRGYIKKKLEHGLTRIWQDVQLKVKTYLLGTDLSIFKYDDFIFVLDIIS 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA1 RLMQVGEEFCGSKSEVLQESIRKQSVNYFKNYHRTRLDELRMFLENETWELCPVKSNFSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLMQVGEEFCGSKSEVLQESIRKQSVNYFKNYHRTRLDELRMFLENETWELCPVKSNFSI 430 440 450 460 470 480 480 490 500 510 520 530 pF1KA1 LQLHEFKFMEQSRSPSVSPSKQPVSTSSKTVTLFEQYCSGGNPFEIQANHKDEETEDVLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQLHEFKFMEQSRSPSVSPSKQPVSTSSKTVTLFEQYCSGGNPFEIQANHKDEETEDVLA 490 500 510 520 530 540 540 550 560 570 580 590 pF1KA1 SNGYESDEQEKSAYQEYDSDSDVPEELKRDYVDEQTGDGPVKSVSRETLKSRKKSDYSLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNGYESDEQEKSAYQEYDSDSDVPEELKRDYVDEQTGDGPVKSVSRETLKSRKKSDYSLN 550 560 570 580 590 600 600 610 620 630 640 650 pF1KA1 KVNAPILTNTTLNVIRLVGKYMQMMNILKPIAFDVIHFMSQLFDYYLYAIYTFFGRNDSL :::::::::::::::::: XP_011 KVNAPILTNTTLNVIRLVDGVSLCCLGWSTVAHLHSLQAPPPGFKPFSCLSLPRSWDYRR 610 620 630 640 650 660 >>XP_016867901 (OMIM: 616465) PREDICTED: syndetin isofor (576 aa) initn: 3726 init1: 3726 opt: 3726 Z-score: 3729.4 bits: 700.7 E(85289): 5.4e-201 Smith-Waterman score: 3726; 100.0% identity (100.0% similar) in 575 aa overlap (383-957:2-576) 360 370 380 390 400 410 pF1KA1 GSNMIGTEETNFDRGYIKKKLEHGLTRIWQDVQLKVKTYLLGTDLSIFKYDDFIFVLDII :::::::::::::::::::::::::::::: XP_016 MDVQLKVKTYLLGTDLSIFKYDDFIFVLDII 10 20 30 420 430 440 450 460 470 pF1KA1 SRLMQVGEEFCGSKSEVLQESIRKQSVNYFKNYHRTRLDELRMFLENETWELCPVKSNFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRLMQVGEEFCGSKSEVLQESIRKQSVNYFKNYHRTRLDELRMFLENETWELCPVKSNFS 40 50 60 70 80 90 480 490 500 510 520 530 pF1KA1 ILQLHEFKFMEQSRSPSVSPSKQPVSTSSKTVTLFEQYCSGGNPFEIQANHKDEETEDVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILQLHEFKFMEQSRSPSVSPSKQPVSTSSKTVTLFEQYCSGGNPFEIQANHKDEETEDVL 100 110 120 130 140 150 540 550 560 570 580 590 pF1KA1 ASNGYESDEQEKSAYQEYDSDSDVPEELKRDYVDEQTGDGPVKSVSRETLKSRKKSDYSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASNGYESDEQEKSAYQEYDSDSDVPEELKRDYVDEQTGDGPVKSVSRETLKSRKKSDYSL 160 170 180 190 200 210 600 610 620 630 640 650 pF1KA1 NKVNAPILTNTTLNVIRLVGKYMQMMNILKPIAFDVIHFMSQLFDYYLYAIYTFFGRNDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKVNAPILTNTTLNVIRLVGKYMQMMNILKPIAFDVIHFMSQLFDYYLYAIYTFFGRNDS 220 230 240 250 260 270 660 670 680 690 700 710 pF1KA1 LESTGLGLSSSRLRTTLNRIQESLIDLEVSADPTATLTAAEERKEKVPSPHLSHLVVLTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LESTGLGLSSSRLRTTLNRIQESLIDLEVSADPTATLTAAEERKEKVPSPHLSHLVVLTS 280 290 300 310 320 330 720 730 740 750 760 770 pF1KA1 GDTLYGLAERVVATESLVFLAEQFEFLQPHLDAVMPAVKKPFLQQFYSQTVSTASELRKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDTLYGLAERVVATESLVFLAEQFEFLQPHLDAVMPAVKKPFLQQFYSQTVSTASELRKP 340 350 360 370 380 390 780 790 800 810 820 830 pF1KA1 IYWIVAGKALDYEQMLLLMANVKWDVKEIMSQHNIYVDALLKEFEQFNRRLNEVSKRVRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IYWIVAGKALDYEQMLLLMANVKWDVKEIMSQHNIYVDALLKEFEQFNRRLNEVSKRVRI 400 410 420 430 440 450 840 850 860 870 880 890 pF1KA1 PLPVSNILWEHCIRLANRTIVEGYANVKKCSNEGRALMQLDFQQFLMKLEKLTDIRPIPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLPVSNILWEHCIRLANRTIVEGYANVKKCSNEGRALMQLDFQQFLMKLEKLTDIRPIPD 460 470 480 490 500 510 900 910 920 930 940 950 pF1KA1 KEFVETYIKAYYLTENDMERWIKEHREYSTKQLTNLVNVCLGSHINKKARQKLLAAIDDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEFVETYIKAYYLTENDMERWIKEHREYSTKQLTNLVNVCLGSHINKKARQKLLAAIDDI 520 530 540 550 560 570 pF1KA1 DRPKR ::::: XP_016 DRPKR >>NP_078829 (OMIM: 616465) syndetin isoform b [Homo sapi (327 aa) initn: 1963 init1: 1963 opt: 1963 Z-score: 1970.7 bits: 374.5 E(85289): 5e-103 Smith-Waterman score: 1963; 100.0% identity (100.0% similar) in 307 aa overlap (1-307:8-314) 10 20 30 40 50 pF1KA1 MTRQGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQAEQELINSIEQV ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 MQKIKSLMTRQGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQAEQELINSIEQV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA1 YFSVDSFDIVKYELEKLPPVLNLQELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 YFSVDSFDIVKYELEKLPPVLNLQELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA1 RVTSLQTGLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 RVTSLQTGLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA1 QRTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 QRTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVA 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA1 LSKICKNFDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 LSKICKNFDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNT 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA1 DTKFQKLQYKDLCTHVTPDSYIPCLADLCKALWEVMLSYYRTMEWHEKHDNEDTASASEG :::::::::::::: NP_078 DTKFQKLQYKDLCTVCSDLITIHISLL 310 320 957 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 22:09:24 2016 done: Wed Nov 2 22:09:26 2016 Total Scan time: 12.370 Total Display time: 0.140 Function used was FASTA [36.3.4 Apr, 2011]