FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1877, 529 aa 1>>>pF1KA1877 529 - 529 aa - 529 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8829+/-0.000788; mu= 17.0034+/- 0.048 mean_var=97.2148+/-18.974, 0's: 0 Z-trim(111.0): 44 B-trim: 108 in 1/49 Lambda= 0.130079 statistics sampled from 11986 (12030) to 11986 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.73), E-opt: 0.2 (0.37), width: 16 Scan time: 3.250 The best scores are: opt bits E(32554) CCDS2073.1 ST6GAL2 gene_id:84620|Hs108|chr2 ( 529) 3680 700.9 9.6e-202 CCDS46380.1 ST6GAL2 gene_id:84620|Hs108|chr2 ( 466) 3060 584.5 9.2e-167 CCDS3285.1 ST6GAL1 gene_id:6480|Hs108|chr3 ( 406) 1107 217.9 1.8e-56 CCDS46973.1 ST6GAL1 gene_id:6480|Hs108|chr3 ( 175) 735 147.8 9.6e-36 >>CCDS2073.1 ST6GAL2 gene_id:84620|Hs108|chr2 (529 aa) initn: 3680 init1: 3680 opt: 3680 Z-score: 3735.4 bits: 700.9 E(32554): 9.6e-202 Smith-Waterman score: 3680; 100.0% identity (100.0% similar) in 529 aa overlap (1-529:1-529) 10 20 30 40 50 60 pF1KA1 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 IQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 IQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLG 430 440 450 460 470 480 490 500 510 520 pF1KA1 AYHPLLYEKLLVQRLNMGTQGDLHRKGKVVLPGFQAVHCPAPSPVIPHS ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 AYHPLLYEKLLVQRLNMGTQGDLHRKGKVVLPGFQAVHCPAPSPVIPHS 490 500 510 520 >>CCDS46380.1 ST6GAL2 gene_id:84620|Hs108|chr2 (466 aa) initn: 3060 init1: 3060 opt: 3060 Z-score: 3107.4 bits: 584.5 E(32554): 9.2e-167 Smith-Waterman score: 3060; 98.2% identity (99.1% similar) in 449 aa overlap (1-449:1-449) 10 20 30 40 50 60 pF1KA1 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 IQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLG :::::::::::::::::::: .. .. : CCDS46 IQENTKEKIQPNPPSSGFIGSFVKIGHIRACSEPRSRDCTPAWTTE 430 440 450 460 >>CCDS3285.1 ST6GAL1 gene_id:6480|Hs108|chr3 (406 aa) initn: 722 init1: 722 opt: 1107 Z-score: 1127.4 bits: 217.9 E(32554): 1.8e-56 Smith-Waterman score: 1107; 48.9% identity (80.1% similar) in 317 aa overlap (205-519:93-406) 180 190 200 210 220 230 pF1KA1 KRHRRQRRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKH ...:. . ::: : ::::: :.::. ::. CCDS32 VSSSSTQDPHRGRQTLGSLRGLAKAKPEASFQVWNKDSSSKNLIPRLQKIWKNYLSMNKY 70 80 90 100 110 120 240 250 260 270 280 290 pF1KA1 GVRFRGKREA-GLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPL-SQLHPRG : ..: . .: : :.::... : .. :. ::.. :. .: . .. : : CCDS32 KVSYKGPGPGIKFSAEALRCHLRDHVNVSMVEVTDFPFNTSEWEGYLPKESIRTKAGPWG 130 140 150 160 170 180 300 310 320 330 340 350 pF1KA1 LRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNP :::: :::.. .:.::.:::.::::::::.::: ....:::.:::::..:::..:. CCDS32 --RCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQLVTTE 190 200 210 220 230 240 360 370 380 390 400 410 pF1KA1 SHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPK .. :. .:::.. ::..:::. : ... ::..::::.:. : .:. .::::::::.:. CCDS32 KR-FLKDSLYNEGILIVWDPSVYHSDIPKWYQNPDYNFFNNYKTYRKLHPNQPFYILKPQ 250 260 270 280 290 420 430 440 450 460 470 pF1KA1 FIWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELY . :.::::.:: . :.:::::::::..::.:::..: .: .::..:: :.:..:.:.. . CCDS32 MPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYYQKF 300 310 320 330 340 350 480 490 500 510 520 pF1KA1 YDAACTLGAYHPLLYEKLLVQRLNMGTQGDLHRKGKVVLPGFQAVHCPAPSPVIPHS .:.:::.:::::::::: ::..::.::. :.. ::..::::...:: CCDS32 FDSACTMGAYHPLLYEKNLVKHLNQGTDEDIYLLGKATLPGFRTIHC 360 370 380 390 400 >>CCDS46973.1 ST6GAL1 gene_id:6480|Hs108|chr3 (175 aa) initn: 722 init1: 722 opt: 735 Z-score: 755.2 bits: 147.8 E(32554): 9.6e-36 Smith-Waterman score: 735; 52.8% identity (86.9% similar) in 176 aa overlap (344-519:1-175) 320 330 340 350 360 370 pF1KA1 IDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSSLYKDVILVAWDPA .:::..:. .. :. .:::.. ::..:::. CCDS46 MNSQLVTTEKR-FLKDSLYNEGILIVWDPS 10 20 380 390 400 410 420 430 pF1KA1 PYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDIIQENTKEKIQPNP : ... ::..::::.:. : .:. .::::::::.:.. :.::::.:: . :.::::: CCDS46 VYHSDIPKWYQNPDYNFFNNYKTYRKLHPNQPFYILKPQMPWELWDILQEISPEEIQPNP 30 40 50 60 70 80 440 450 460 470 480 490 pF1KA1 PSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQ ::::..::.:::..: .: .::..:: :.:..:.:.. ..:.:::.:::::::::: ::. CCDS46 PSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYYQKFFDSACTMGAYHPLLYEKNLVK 90 100 110 120 130 140 500 510 520 pF1KA1 RLNMGTQGDLHRKGKVVLPGFQAVHCPAPSPVIPHS .::.::. :.. ::..::::...:: CCDS46 HLNQGTDEDIYLLGKATLPGFRTIHC 150 160 170 529 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:56:40 2016 done: Sat Nov 5 06:56:41 2016 Total Scan time: 3.250 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]