FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1877, 529 aa 1>>>pF1KA1877 529 - 529 aa - 529 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1449+/-0.000345; mu= 15.5806+/- 0.021 mean_var=103.6151+/-20.579, 0's: 0 Z-trim(118.0): 163 B-trim: 461 in 1/50 Lambda= 0.125998 statistics sampled from 30301 (30476) to 30301 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.72), E-opt: 0.2 (0.357), width: 16 Scan time: 10.450 The best scores are: opt bits E(85289) NP_001135823 (OMIM: 608472) beta-galactoside alpha ( 529) 3680 679.5 6.7e-195 XP_011510301 (OMIM: 608472) PREDICTED: beta-galact ( 529) 3680 679.5 6.7e-195 NP_115917 (OMIM: 608472) beta-galactoside alpha-2, ( 529) 3680 679.5 6.7e-195 NP_001309291 (OMIM: 608472) beta-galactoside alpha ( 529) 3680 679.5 6.7e-195 XP_006712865 (OMIM: 608472) PREDICTED: beta-galact ( 529) 3680 679.5 6.7e-195 NP_001135824 (OMIM: 608472) beta-galactoside alpha ( 466) 3060 566.8 5.1e-161 XP_011510303 (OMIM: 608472) PREDICTED: beta-galact ( 466) 3060 566.8 5.1e-161 XP_011510302 (OMIM: 608472) PREDICTED: beta-galact ( 469) 3053 565.5 1.2e-160 XP_016860599 (OMIM: 608472) PREDICTED: beta-galact ( 475) 3049 564.8 2.1e-160 NP_003023 (OMIM: 109675) beta-galactoside alpha-2, ( 406) 1107 211.7 3.4e-54 XP_016862554 (OMIM: 109675) PREDICTED: beta-galact ( 406) 1107 211.7 3.4e-54 XP_011511387 (OMIM: 109675) PREDICTED: beta-galact ( 406) 1107 211.7 3.4e-54 XP_006713797 (OMIM: 109675) PREDICTED: beta-galact ( 406) 1107 211.7 3.4e-54 XP_005247777 (OMIM: 109675) PREDICTED: beta-galact ( 406) 1107 211.7 3.4e-54 XP_005247776 (OMIM: 109675) PREDICTED: beta-galact ( 406) 1107 211.7 3.4e-54 NP_775323 (OMIM: 109675) beta-galactoside alpha-2, ( 406) 1107 211.7 3.4e-54 XP_016862555 (OMIM: 109675) PREDICTED: beta-galact ( 406) 1107 211.7 3.4e-54 XP_016862557 (OMIM: 109675) PREDICTED: beta-galact ( 406) 1107 211.7 3.4e-54 XP_016862556 (OMIM: 109675) PREDICTED: beta-galact ( 406) 1107 211.7 3.4e-54 XP_011511388 (OMIM: 109675) PREDICTED: beta-galact ( 406) 1107 211.7 3.4e-54 NP_775324 (OMIM: 109675) beta-galactoside alpha-2, ( 175) 735 143.8 4e-34 NP_001310288 (OMIM: 607156) type 2 lactosamine alp ( 223) 290 63.0 1.1e-09 NP_001310287 (OMIM: 607156) type 2 lactosamine alp ( 223) 290 63.0 1.1e-09 NP_001258071 (OMIM: 607156) type 2 lactosamine alp ( 245) 290 63.0 1.2e-09 NP_001310289 (OMIM: 607156) type 2 lactosamine alp ( 245) 290 63.0 1.2e-09 NP_001310295 (OMIM: 607156) type 2 lactosamine alp ( 245) 290 63.0 1.2e-09 NP_001310297 (OMIM: 607156) type 2 lactosamine alp ( 331) 290 63.1 1.5e-09 NP_001310294 (OMIM: 607156) type 2 lactosamine alp ( 331) 290 63.1 1.5e-09 NP_006091 (OMIM: 607156) type 2 lactosamine alpha- ( 331) 290 63.1 1.5e-09 NP_001310281 (OMIM: 607156) type 2 lactosamine alp ( 331) 290 63.1 1.5e-09 NP_001258075 (OMIM: 607156) type 2 lactosamine alp ( 331) 290 63.1 1.5e-09 NP_001310296 (OMIM: 607156) type 2 lactosamine alp ( 354) 290 63.2 1.6e-09 NP_001258074 (OMIM: 607156) type 2 lactosamine alp ( 384) 290 63.2 1.7e-09 NP_006269 (OMIM: 104240) CMP-N-acetylneuraminate-b ( 329) 268 59.1 2.3e-08 XP_016873623 (OMIM: 104240) PREDICTED: CMP-N-acety ( 329) 268 59.1 2.3e-08 NP_001241688 (OMIM: 104240) CMP-N-acetylneuraminat ( 332) 268 59.1 2.4e-08 NP_001241687 (OMIM: 104240) CMP-N-acetylneuraminat ( 333) 268 59.1 2.4e-08 NP_001241686 (OMIM: 104240) CMP-N-acetylneuraminat ( 333) 268 59.1 2.4e-08 NP_112227 (OMIM: 610134) alpha-N-acetylgalactosami ( 336) 268 59.1 2.4e-08 XP_011516913 (OMIM: 610135) PREDICTED: alpha-N-ace ( 299) 262 58.0 4.6e-08 XP_016870156 (OMIM: 610135) PREDICTED: alpha-N-ace ( 299) 262 58.0 4.6e-08 NP_001273929 (OMIM: 610135) alpha-N-acetylgalactos ( 299) 262 58.0 4.6e-08 NP_001273930 (OMIM: 610135) alpha-N-acetylgalactos ( 299) 262 58.0 4.6e-08 XP_016870155 (OMIM: 610135) PREDICTED: alpha-N-ace ( 299) 262 58.0 4.6e-08 XP_016870154 (OMIM: 610135) PREDICTED: alpha-N-ace ( 299) 262 58.0 4.6e-08 NP_001273931 (OMIM: 610135) alpha-N-acetylgalactos ( 299) 262 58.0 4.6e-08 XP_016857610 (OMIM: 606494) PREDICTED: CMP-N-acety ( 268) 261 57.8 4.8e-08 XP_016857609 (OMIM: 606494) PREDICTED: CMP-N-acety ( 268) 261 57.8 4.8e-08 XP_016857608 (OMIM: 606494) PREDICTED: CMP-N-acety ( 282) 261 57.8 5e-08 NP_038471 (OMIM: 610135) alpha-N-acetylgalactosami ( 333) 262 58.0 5e-08 >>NP_001135823 (OMIM: 608472) beta-galactoside alpha-2,6 (529 aa) initn: 3680 init1: 3680 opt: 3680 Z-score: 3620.1 bits: 679.5 E(85289): 6.7e-195 Smith-Waterman score: 3680; 100.0% identity (100.0% similar) in 529 aa overlap (1-529:1-529) 10 20 30 40 50 60 pF1KA1 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 IQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLG 430 440 450 460 470 480 490 500 510 520 pF1KA1 AYHPLLYEKLLVQRLNMGTQGDLHRKGKVVLPGFQAVHCPAPSPVIPHS ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AYHPLLYEKLLVQRLNMGTQGDLHRKGKVVLPGFQAVHCPAPSPVIPHS 490 500 510 520 >>XP_011510301 (OMIM: 608472) PREDICTED: beta-galactosid (529 aa) initn: 3680 init1: 3680 opt: 3680 Z-score: 3620.1 bits: 679.5 E(85289): 6.7e-195 Smith-Waterman score: 3680; 100.0% identity (100.0% similar) in 529 aa overlap (1-529:1-529) 10 20 30 40 50 60 pF1KA1 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 IQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLG 430 440 450 460 470 480 490 500 510 520 pF1KA1 AYHPLLYEKLLVQRLNMGTQGDLHRKGKVVLPGFQAVHCPAPSPVIPHS ::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AYHPLLYEKLLVQRLNMGTQGDLHRKGKVVLPGFQAVHCPAPSPVIPHS 490 500 510 520 >>NP_115917 (OMIM: 608472) beta-galactoside alpha-2,6-si (529 aa) initn: 3680 init1: 3680 opt: 3680 Z-score: 3620.1 bits: 679.5 E(85289): 6.7e-195 Smith-Waterman score: 3680; 100.0% identity (100.0% similar) in 529 aa overlap (1-529:1-529) 10 20 30 40 50 60 pF1KA1 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 IQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 IQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLG 430 440 450 460 470 480 490 500 510 520 pF1KA1 AYHPLLYEKLLVQRLNMGTQGDLHRKGKVVLPGFQAVHCPAPSPVIPHS ::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 AYHPLLYEKLLVQRLNMGTQGDLHRKGKVVLPGFQAVHCPAPSPVIPHS 490 500 510 520 >>NP_001309291 (OMIM: 608472) beta-galactoside alpha-2,6 (529 aa) initn: 3680 init1: 3680 opt: 3680 Z-score: 3620.1 bits: 679.5 E(85289): 6.7e-195 Smith-Waterman score: 3680; 100.0% identity (100.0% similar) in 529 aa overlap (1-529:1-529) 10 20 30 40 50 60 pF1KA1 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 IQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLG 430 440 450 460 470 480 490 500 510 520 pF1KA1 AYHPLLYEKLLVQRLNMGTQGDLHRKGKVVLPGFQAVHCPAPSPVIPHS ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AYHPLLYEKLLVQRLNMGTQGDLHRKGKVVLPGFQAVHCPAPSPVIPHS 490 500 510 520 >>XP_006712865 (OMIM: 608472) PREDICTED: beta-galactosid (529 aa) initn: 3680 init1: 3680 opt: 3680 Z-score: 3620.1 bits: 679.5 E(85289): 6.7e-195 Smith-Waterman score: 3680; 100.0% identity (100.0% similar) in 529 aa overlap (1-529:1-529) 10 20 30 40 50 60 pF1KA1 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 IQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLG 430 440 450 460 470 480 490 500 510 520 pF1KA1 AYHPLLYEKLLVQRLNMGTQGDLHRKGKVVLPGFQAVHCPAPSPVIPHS ::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AYHPLLYEKLLVQRLNMGTQGDLHRKGKVVLPGFQAVHCPAPSPVIPHS 490 500 510 520 >>NP_001135824 (OMIM: 608472) beta-galactoside alpha-2,6 (466 aa) initn: 3060 init1: 3060 opt: 3060 Z-score: 3011.8 bits: 566.8 E(85289): 5.1e-161 Smith-Waterman score: 3060; 98.2% identity (99.1% similar) in 449 aa overlap (1-449:1-449) 10 20 30 40 50 60 pF1KA1 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 IQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLG :::::::::::::::::::: .. .. : NP_001 IQENTKEKIQPNPPSSGFIGSFVKIGHIRACSEPRSRDCTPAWTTE 430 440 450 460 >>XP_011510303 (OMIM: 608472) PREDICTED: beta-galactosid (466 aa) initn: 3060 init1: 3060 opt: 3060 Z-score: 3011.8 bits: 566.8 E(85289): 5.1e-161 Smith-Waterman score: 3060; 98.2% identity (99.1% similar) in 449 aa overlap (1-449:1-449) 10 20 30 40 50 60 pF1KA1 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 IQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLG :::::::::::::::::::: .. .. : XP_011 IQENTKEKIQPNPPSSGFIGSFVKIGHIRACSEPRSRDCTPAWTTE 430 440 450 460 >>XP_011510302 (OMIM: 608472) PREDICTED: beta-galactosid (469 aa) initn: 3053 init1: 3053 opt: 3053 Z-score: 3004.9 bits: 565.5 E(85289): 1.2e-160 Smith-Waterman score: 3053; 99.5% identity (100.0% similar) in 442 aa overlap (1-442:1-442) 10 20 30 40 50 60 pF1KA1 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 IQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLG :::::::::::::::::::..: XP_011 IQENTKEKIQPNPPSSGFIALLGHPHNMAAGFQRTGDLRKSKEEGPMFL 430 440 450 460 >>XP_016860599 (OMIM: 608472) PREDICTED: beta-galactosid (475 aa) initn: 3046 init1: 3046 opt: 3049 Z-score: 3000.9 bits: 564.8 E(85289): 2.1e-160 Smith-Waterman score: 3049; 98.4% identity (98.9% similar) in 449 aa overlap (1-448:1-445) 10 20 30 40 50 60 pF1KA1 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 370 380 390 400 410 420 430 440 450 460 470 pF1KA1 IQENTKEKIQPNPPSSGFI-GILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTL ::::::::::::::::::: :. :.: XP_016 IQENTKEKIQPNPPSSGFIDGV----SLCYSGWSAVARSQLTATSASQVQAILLPQPPK 430 440 450 460 470 >>NP_003023 (OMIM: 109675) beta-galactoside alpha-2,6-si (406 aa) initn: 722 init1: 722 opt: 1107 Z-score: 1094.0 bits: 211.7 E(85289): 3.4e-54 Smith-Waterman score: 1107; 48.9% identity (80.1% similar) in 317 aa overlap (205-519:93-406) 180 190 200 210 220 230 pF1KA1 KRHRRQRRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKH ...:. . ::: : ::::: :.::. ::. NP_003 VSSSSTQDPHRGRQTLGSLRGLAKAKPEASFQVWNKDSSSKNLIPRLQKIWKNYLSMNKY 70 80 90 100 110 120 240 250 260 270 280 290 pF1KA1 GVRFRGKREA-GLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPL-SQLHPRG : ..: . .: : :.::... : .. :. ::.. :. .: . .. : : NP_003 KVSYKGPGPGIKFSAEALRCHLRDHVNVSMVEVTDFPFNTSEWEGYLPKESIRTKAGPWG 130 140 150 160 170 180 300 310 320 330 340 350 pF1KA1 LRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNP :::: :::.. .:.::.:::.::::::::.::: ....:::.:::::..:::..:. NP_003 --RCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQLVTTE 190 200 210 220 230 240 360 370 380 390 400 410 pF1KA1 SHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPK .. :. .:::.. ::..:::. : ... ::..::::.:. : .:. .::::::::.:. NP_003 KR-FLKDSLYNEGILIVWDPSVYHSDIPKWYQNPDYNFFNNYKTYRKLHPNQPFYILKPQ 250 260 270 280 290 420 430 440 450 460 470 pF1KA1 FIWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELY . :.::::.:: . :.:::::::::..::.:::..: .: .::..:: :.:..:.:.. . NP_003 MPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYYQKF 300 310 320 330 340 350 480 490 500 510 520 pF1KA1 YDAACTLGAYHPLLYEKLLVQRLNMGTQGDLHRKGKVVLPGFQAVHCPAPSPVIPHS .:.:::.:::::::::: ::..::.::. :.. ::..::::...:: NP_003 FDSACTMGAYHPLLYEKNLVKHLNQGTDEDIYLLGKATLPGFRTIHC 360 370 380 390 400 529 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:56:41 2016 done: Sat Nov 5 06:56:43 2016 Total Scan time: 10.450 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]