FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1880, 612 aa 1>>>pF1KA1880 612 - 612 aa - 612 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1610+/-0.0011; mu= 14.8955+/- 0.066 mean_var=86.5342+/-18.046, 0's: 0 Z-trim(104.5): 129 B-trim: 515 in 1/50 Lambda= 0.137873 statistics sampled from 7796 (7943) to 7796 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.61), E-opt: 0.2 (0.244), width: 16 Scan time: 2.760 The best scores are: opt bits E(32554) CCDS47418.1 BTBD9 gene_id:114781|Hs108|chr6 ( 612) 4097 825.5 0 CCDS43458.1 BTBD9 gene_id:114781|Hs108|chr6 ( 544) 3641 734.8 7.1e-212 CCDS54998.1 BTBD9 gene_id:114781|Hs108|chr6 ( 582) 2146 437.4 2.5e-122 CCDS12078.1 BTBD2 gene_id:55643|Hs108|chr19 ( 525) 353 80.7 5.2e-15 CCDS32313.1 BTBD1 gene_id:53339|Hs108|chr15 ( 385) 345 79.1 1.2e-14 CCDS10322.1 BTBD1 gene_id:53339|Hs108|chr15 ( 482) 345 79.1 1.5e-14 CCDS10002.2 BTBD6 gene_id:90135|Hs108|chr14 ( 485) 335 77.1 5.8e-14 CCDS13114.1 BTBD3 gene_id:22903|Hs108|chr20 ( 461) 321 74.3 3.8e-13 CCDS13113.1 BTBD3 gene_id:22903|Hs108|chr20 ( 522) 321 74.4 4.3e-13 CCDS1310.1 KLHL20 gene_id:27252|Hs108|chr1 ( 609) 318 73.8 7.3e-13 CCDS58970.1 KLHL3 gene_id:26249|Hs108|chr5 ( 555) 312 72.6 1.6e-12 CCDS4192.1 KLHL3 gene_id:26249|Hs108|chr5 ( 587) 312 72.6 1.6e-12 CCDS10339.1 KLHL25 gene_id:64410|Hs108|chr15 ( 589) 305 71.2 4.3e-12 CCDS3245.2 KLHL6 gene_id:89857|Hs108|chr3 ( 621) 299 70.0 1e-11 CCDS34094.1 KLHL2 gene_id:11275|Hs108|chr4 ( 593) 298 69.8 1.1e-11 CCDS54815.1 KLHL2 gene_id:11275|Hs108|chr4 ( 597) 298 69.8 1.1e-11 CCDS3246.1 KLHL24 gene_id:54800|Hs108|chr3 ( 600) 296 69.4 1.5e-11 CCDS1429.1 KLHL12 gene_id:59349|Hs108|chr1 ( 568) 291 68.4 2.9e-11 CCDS44132.1 IPP gene_id:3652|Hs108|chr1 ( 582) 284 67.0 7.7e-11 CCDS30702.1 IPP gene_id:3652|Hs108|chr1 ( 584) 284 67.0 7.7e-11 CCDS30575.1 KLHL21 gene_id:9903|Hs108|chr1 ( 597) 284 67.0 7.8e-11 >>CCDS47418.1 BTBD9 gene_id:114781|Hs108|chr6 (612 aa) initn: 4097 init1: 4097 opt: 4097 Z-score: 4406.7 bits: 825.5 E(32554): 0 Smith-Waterman score: 4097; 100.0% identity (100.0% similar) in 612 aa overlap (1-612:1-612) 10 20 30 40 50 60 pF1KA1 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 FRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 FRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 GFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 GFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 LSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 PSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 PSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 QNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 QNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 VRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 VRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 IVPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 IVPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 IGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 IGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 THNTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSLAGQQLDSHALRAPSGSSLPSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 THNTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSLAGQQLDSHALRAPSGSSLPSSP 550 560 570 580 590 600 610 pF1KA1 GSNSRSPNRQHQ :::::::::::: CCDS47 GSNSRSPNRQHQ 610 >>CCDS43458.1 BTBD9 gene_id:114781|Hs108|chr6 (544 aa) initn: 3641 init1: 3641 opt: 3641 Z-score: 3917.3 bits: 734.8 E(32554): 7.1e-212 Smith-Waterman score: 3641; 100.0% identity (100.0% similar) in 544 aa overlap (69-612:1-544) 40 50 60 70 80 90 pF1KA1 TFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTG :::::::::::::::::::::::::::::: CCDS43 MRESQPEAEIPLQDTTAEAFTMLLKYIYTG 10 20 30 100 110 120 130 140 150 pF1KA1 RATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 RATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLT 40 50 60 70 80 90 160 170 180 190 200 210 pF1KA1 CMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 CMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENH 100 110 120 130 140 150 220 230 240 250 260 270 pF1KA1 AEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 AEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIA 160 170 180 190 200 210 280 290 300 310 320 330 pF1KA1 TMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 TMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRIL 220 230 240 250 260 270 340 350 360 370 380 390 pF1KA1 LWDRDSRSYSYFIEVSMDELDWVRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LWDRDSRSYSYFIEVSMDELDWVRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNK 280 290 300 310 320 330 400 410 420 430 440 450 pF1KA1 IFHIVAFECMFTNKTFTLEKGLIVPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 IFHIVAFECMFTNKTFTLEKGLIVPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWD 340 350 360 370 380 390 460 470 480 490 500 510 pF1KA1 SGYTCHQLGSGAIVVQLAQPYMIGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SGYTCHQLGSGAIVVQLAQPYMIGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKV 400 410 420 430 440 450 520 530 540 550 560 570 pF1KA1 SCKSWQSVTFERQPASFIRIVGTHNTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SCKSWQSVTFERQPASFIRIVGTHNTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSL 460 470 480 490 500 510 580 590 600 610 pF1KA1 AGQQLDSHALRAPSGSSLPSSPGSNSRSPNRQHQ :::::::::::::::::::::::::::::::::: CCDS43 AGQQLDSHALRAPSGSSLPSSPGSNSRSPNRQHQ 520 530 540 >>CCDS54998.1 BTBD9 gene_id:114781|Hs108|chr6 (582 aa) initn: 2251 init1: 2146 opt: 2146 Z-score: 2309.8 bits: 437.4 E(32554): 2.5e-122 Smith-Waterman score: 3619; 95.0% identity (95.0% similar) in 580 aa overlap (62-612:3-582) 40 50 60 70 80 90 pF1KA1 GEEYGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTML :::::::::::::::::::::::::::::: CCDS54 MCRALLYGGMRESQPEAEIPLQDTTAEAFTML 10 20 30 100 110 120 130 140 150 pF1KA1 LKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASL 40 50 60 70 80 90 160 170 180 190 200 210 pF1KA1 YSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNWCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 YSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNWCK 100 110 120 130 140 150 220 230 240 250 260 270 pF1KA1 HNSKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSESRDMDLNYRGML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 HNSKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSESRDMDLNYRGML 160 170 180 190 200 210 280 290 300 310 320 330 pF1KA1 IPEENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 IPEENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSI 220 230 240 250 260 270 340 350 360 370 380 pF1KA1 INHIRILLWDRDSRSYSYFIEVSMDELDWVRVIDHSQYLCRSWQKLYFPARVC------- ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 INHIRILLWDRDSRSYSYFIEVSMDELDWVRVIDHSQYLCRSWQKLYFPARVCSGDGVSL 280 290 300 310 320 330 390 400 410 420 pF1KA1 ----------------------RYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGLIV :::::::::::::::::::::::::::::::::::::: CCDS54 WCPLWSRTPELKQSSLLGLPKCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGLIV 340 350 360 370 380 390 430 440 450 460 470 480 pF1KA1 PMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYMIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 PMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYMIG 400 410 420 430 440 450 490 500 510 520 530 540 pF1KA1 SIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVGTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 SIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVGTH 460 470 480 490 500 510 550 560 570 580 590 600 pF1KA1 NTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSLAGQQLDSHALRAPSGSSLPSSPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 NTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSLAGQQLDSHALRAPSGSSLPSSPGS 520 530 540 550 560 570 610 pF1KA1 NSRSPNRQHQ :::::::::: CCDS54 NSRSPNRQHQ 580 >>CCDS12078.1 BTBD2 gene_id:55643|Hs108|chr19 (525 aa) initn: 209 init1: 96 opt: 353 Z-score: 383.0 bits: 80.7 E(32554): 5.2e-15 Smith-Waterman score: 353; 29.6% identity (60.0% similar) in 240 aa overlap (22-245:103-337) 10 20 30 40 pF1KA1 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEK----KRF ..:... :. .: :: :.: : .:. CCDS12 GAERAEEAAGPGAAALQREAAYNWQASKPTVQERFAFLFNNEVLCDVHFLVGKGLSSQRI 80 90 100 110 120 130 50 60 70 80 90 100 pF1KA1 PAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKE :::: .::. : :.. ::: .. : :.: :. :: :::..:. .. . : CCDS12 PAHRFVLAVGSAVFDAMFNGGMATTSTEIELP--DVEPAAFLALLKFLYSDEVQIGPE-- 140 150 160 170 180 110 120 130 140 150 160 pF1KA1 EVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDR ... : :.::. : :: :.: : .:. : . : :.. :.:. .: .:. CCDS12 -TVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASLCLENIDK 190 200 210 220 230 240 170 180 190 200 210 pF1KA1 NAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNW----CKHN----SKENHA :. .....::: ... .:. .. ::... : .: :.. : :... . ::. CCDS12 NTADAITAEGFTDIDLDTLVAVLERDTLGIREVRLFNAVVRWSEAECQRQQLQVTPENRR 250 260 270 280 290 300 220 230 240 250 260 270 pF1KA1 EIMQA----VRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEE ... .:.:::.. :. ::.: CCDS12 KVLGKALGLIRFPLMTIEEFAAGPAQSGILVDREVVSLFLHFTVNPKPRVEFIDRPRCCL 310 320 330 340 350 360 >>CCDS32313.1 BTBD1 gene_id:53339|Hs108|chr15 (385 aa) initn: 252 init1: 110 opt: 345 Z-score: 376.4 bits: 79.1 E(32554): 1.2e-14 Smith-Waterman score: 357; 28.5% identity (59.3% similar) in 253 aa overlap (22-252:55-302) 10 20 30 40 pF1KA1 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEK------- :.:... :. .: .:: ::. : CCDS32 PPPPPSPSSLGPLLPLQREPLYNWQATKASLKERFAFLFNSELLSDVRFVLGKGRGAAAA 30 40 50 60 70 80 50 60 70 80 90 100 pF1KA1 ---KRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRAT .:.:::: .::: : :.. ::: .. : :.: :. :: ::...:. .. CCDS32 GGPQRIPAHRFVLAAGSAVFDAMFNGGMATTSAEIELP--DVEPAAFLALLRFLYSDEVQ 90 100 110 120 130 140 110 120 130 140 150 160 pF1KA1 LTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMC . :... : :.::. : :: :.: : .:. : . : :.. :.:. .: CCDS32 IGP---ETVMTTLYTAKKYAVPALEAHCVEFLTKHLRADNAFMLLTQARLFDEPQLASLC 150 160 170 180 190 170 180 190 200 210 pF1KA1 CMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNW----CKH----- .:.......:.::: ... .: .. ::... :. .: :.. : :.. CCDS32 LDTIDKSTMDAISAEGFTDIDIDTLCAVLERDTLSIRESRLFGAVVRWAEAECQRQQLPV 200 210 220 230 240 250 220 230 240 250 260 pF1KA1 ---NSKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSESRDMDLNYRG :... .. .. .:.:::.. :. ::.:: ... CCDS32 TFGNKQKVLGKALSLIRFPLMTIEEFAAGPAQSGILSDREVVNLFLHFTVNPKPRVEYID 260 270 280 290 300 310 270 280 290 300 310 320 pF1KA1 MLIPEENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQP CCDS32 RPRCCLRGKECCINRFQQVESRWGYSGTSDRIRSLNMRKSKPWDRMIPALVVMGQLTHSG 320 330 340 350 360 370 >>CCDS10322.1 BTBD1 gene_id:53339|Hs108|chr15 (482 aa) initn: 252 init1: 110 opt: 345 Z-score: 374.9 bits: 79.1 E(32554): 1.5e-14 Smith-Waterman score: 357; 28.5% identity (59.3% similar) in 253 aa overlap (22-252:55-302) 10 20 30 40 pF1KA1 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEK------- :.:... :. .: .:: ::. : CCDS10 PPPPPSPSSLGPLLPLQREPLYNWQATKASLKERFAFLFNSELLSDVRFVLGKGRGAAAA 30 40 50 60 70 80 50 60 70 80 90 100 pF1KA1 ---KRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRAT .:.:::: .::: : :.. ::: .. : :.: :. :: ::...:. .. CCDS10 GGPQRIPAHRFVLAAGSAVFDAMFNGGMATTSAEIELP--DVEPAAFLALLRFLYSDEVQ 90 100 110 120 130 140 110 120 130 140 150 160 pF1KA1 LTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMC . :... : :.::. : :: :.: : .:. : . : :.. :.:. .: CCDS10 IGP---ETVMTTLYTAKKYAVPALEAHCVEFLTKHLRADNAFMLLTQARLFDEPQLASLC 150 160 170 180 190 170 180 190 200 210 pF1KA1 CMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNW----CKH----- .:.......:.::: ... .: .. ::... :. .: :.. : :.. CCDS10 LDTIDKSTMDAISAEGFTDIDIDTLCAVLERDTLSIRESRLFGAVVRWAEAECQRQQLPV 200 210 220 230 240 250 220 230 240 250 260 pF1KA1 ---NSKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSESRDMDLNYRG :... .. .. .:.:::.. :. ::.:: ... CCDS10 TFGNKQKVLGKALSLIRFPLMTIEEFAAGPAQSGILSDREVVNLFLHFTVNPKPRVEYID 260 270 280 290 300 310 270 280 290 300 310 320 pF1KA1 MLIPEENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQP CCDS10 RPRCCLRGKECCINRFQQVESRWGYSGTSDRIRFTVNRRISIVGFGLYGSIHGPTDYQVN 320 330 340 350 360 370 >>CCDS10002.2 BTBD6 gene_id:90135|Hs108|chr14 (485 aa) initn: 275 init1: 118 opt: 335 Z-score: 364.2 bits: 77.1 E(32554): 5.8e-14 Smith-Waterman score: 367; 30.4% identity (57.9% similar) in 273 aa overlap (22-274:69-336) 10 20 30 40 pF1KA1 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVV----EKKRF : :. . .. .: ..:: ::: . CCDS10 APAPPPPAPAPPTLGNNHQESPGWRCCRPTLRERNALMFNNELMADVHFVVGPPGATRTV 40 50 60 70 80 90 50 60 70 80 90 100 pF1KA1 PAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKE :::. .::. . : :..:: . : . : .:: :. :: .::::.:. . : . CCDS10 PAHKYVLAVGSSVFYAMFYGDLAEVKSEIHIP--DVEPAAFLILLKYMYSDEI---DLEA 100 110 120 130 140 150 110 120 130 140 150 160 pF1KA1 EVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDR ...: : :.:: : : . ..: : :. .:.:. .. . :. :.:: : .: CCDS10 DTVLATLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQSRLFEEPELTQRCWEVIDA 160 170 180 190 200 210 170 180 190 200 210 pF1KA1 NAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNW----CKH--------NSK .:. .: :::: ... .: :: :... . : .: :.::: ::. :.. CCDS10 QAEMALRSEGFCEIDRQTLEIIVTREALNTKEAVVFEAVLNWAEAECKRQGLPITPRNKR 220 230 240 250 260 270 220 230 240 250 260 270 pF1KA1 ENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPD---AILDAIKVRSESR-DMDLNYRGML . .. . ::.: :.: :. : . : .:. . .:. . .. : :. :. : : CCDS10 HVLGRALYLVRIPTMTLEEFANGAAQSDILTLEETHSIFLWYTATNKPRLDFPLTKRKGL 280 290 300 310 320 330 280 290 300 310 320 330 pF1KA1 IPEENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSI :. CCDS10 APQRCHRFQSSAYRSNQWRYRGRCDSIQFAVDRRVFIAGLGLYGSSSGKAEYSVKIELKR 340 350 360 370 380 390 >>CCDS13114.1 BTBD3 gene_id:22903|Hs108|chr20 (461 aa) initn: 287 init1: 155 opt: 321 Z-score: 349.4 bits: 74.3 E(32554): 3.8e-13 Smith-Waterman score: 358; 28.9% identity (59.3% similar) in 273 aa overlap (22-274:45-312) 10 20 30 40 pF1KA1 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEK----KRF . :. . .. .. ..:: ::: .:. CCDS13 SSTSVQQYHQQNLSNNNLIPAPNWQGLYPTIRERNAMMFNNDLMADVHFVVGPPGGTQRL 20 30 40 50 60 70 50 60 70 80 90 100 pF1KA1 PAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKE :.:. .::. . :.:..:: . :.. : .:: :. :: .::::: . :. CCDS13 PGHKYVLAVGSSVFHAMFYGELAEDKDEIRIP--DVEPAAFLAMLKYIYCDEIDLA---A 80 90 100 110 120 110 120 130 140 150 160 pF1KA1 EVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDR ...: : :.:: :.: . ..: : :. .:.:. .. . :. : :: : .: CCDS13 DTVLATLYAAKKYIVPHLARACVNFLETSLSAKNACVLLSQSCLFEEPDLTQRCWEVIDA 130 140 150 160 170 180 170 180 190 200 210 pF1KA1 NAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNW----CKHN----SKENHA .:. .:.:::: ... .: .:. :... : : .: : ::: :... : ::. CCDS13 QAELALKSEGFCDIDFQTLESILRRETLNAKEIVVFEAALNWAEVECQRQDLALSIENKR 190 200 210 220 230 240 220 230 240 250 260 270 pF1KA1 EIMQA----VRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSESRDMDLNY----RGML ... .:.: :.: .. : . ::.:. . : . . .. .:.. : : CCDS13 KVLGKALYLIRIPTMALDDFANGAAQSGVLTLNETNDIFLWYTAAKKPELQFVSKARKGL 250 260 270 280 290 300 280 290 300 310 320 330 pF1KA1 IPEENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSI .:. CCDS13 VPQRCHRFQSCAYRSNQWRYRGRCDSIQFAVDKRVFIAGFGLYGSSCGSAEYSAKIELKR 310 320 330 340 350 360 >>CCDS13113.1 BTBD3 gene_id:22903|Hs108|chr20 (522 aa) initn: 287 init1: 155 opt: 321 Z-score: 348.6 bits: 74.4 E(32554): 4.3e-13 Smith-Waterman score: 358; 28.9% identity (59.3% similar) in 273 aa overlap (22-274:106-373) 10 20 30 40 pF1KA1 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEK----KRF . :. . .. .. ..:: ::: .:. CCDS13 SSTSVQQYHQQNLSNNNLIPAPNWQGLYPTIRERNAMMFNNDLMADVHFVVGPPGGTQRL 80 90 100 110 120 130 50 60 70 80 90 100 pF1KA1 PAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKE :.:. .::. . :.:..:: . :.. : .:: :. :: .::::: . :. CCDS13 PGHKYVLAVGSSVFHAMFYGELAEDKDEIRIP--DVEPAAFLAMLKYIYCDEIDLA---A 140 150 160 170 180 190 110 120 130 140 150 160 pF1KA1 EVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDR ...: : :.:: :.: . ..: : :. .:.:. .. . :. : :: : .: CCDS13 DTVLATLYAAKKYIVPHLARACVNFLETSLSAKNACVLLSQSCLFEEPDLTQRCWEVIDA 200 210 220 230 240 250 170 180 190 200 210 pF1KA1 NAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNW----CKHN----SKENHA .:. .:.:::: ... .: .:. :... : : .: : ::: :... : ::. CCDS13 QAELALKSEGFCDIDFQTLESILRRETLNAKEIVVFEAALNWAEVECQRQDLALSIENKR 260 270 280 290 300 310 220 230 240 250 260 270 pF1KA1 EIMQA----VRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSESRDMDLNY----RGML ... .:.: :.: .. : . ::.:. . : . . .. .:.. : : CCDS13 KVLGKALYLIRIPTMALDDFANGAAQSGVLTLNETNDIFLWYTAAKKPELQFVSKARKGL 320 330 340 350 360 370 280 290 300 310 320 330 pF1KA1 IPEENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSI .:. CCDS13 VPQRCHRFQSCAYRSNQWRYRGRCDSIQFAVDKRVFIAGFGLYGSSCGSAEYSAKIELKR 380 390 400 410 420 430 >>CCDS1310.1 KLHL20 gene_id:27252|Hs108|chr1 (609 aa) initn: 203 init1: 113 opt: 318 Z-score: 344.4 bits: 73.8 E(32554): 7.3e-13 Smith-Waterman score: 327; 28.8% identity (59.4% similar) in 281 aa overlap (1-275:46-299) 10 20 30 pF1KA1 MSNSHPLRPFTAVGEIDHVHILSEHIGALL .:..:: . . :. ...: .: CCDS13 ETGMDVTSRCTLGDPNKLPEGVPQPARMPYISDKHPRQTL----EV--INLLRKH----- 20 30 40 50 60 40 50 60 70 80 90 pF1KA1 IGEEYGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTM .: ::..:: :.. ::::::.: ::::.. : . ::. ..:. ..: .:. . CCDS13 --RELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESR-QTEVVIRDIDERAMEL 70 80 90 100 110 120 100 110 120 130 140 pF1KA1 LLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDV-A :. . ::.. :. . . ..:: : . . :.... :.: :. .: :. . . : CCDS13 LIDFAYTSQITVEEGNVQTLLPAACLLQ---LAEIQEACCEFLKRQLDPSN-CLGIRAFA 130 140 150 160 170 150 160 170 180 190 200 pF1KA1 SLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAA-PEKDIFLALLN . .: .: . : ..: :::. :: :. : . :..:. : . . :...: :.. CCDS13 DTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMA 180 190 200 210 220 230 210 220 230 240 250 260 pF1KA1 WCKHNSKENHAE---IMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSESRDM-D : :.. .: . . ..: :::::.: :...: . :.. : : ::. : CCDS13 WVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSD---------EECRDLVD 240 250 260 270 280 270 280 290 300 310 320 pF1KA1 LNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEI .:.:.: CCDS13 EAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMV 290 300 310 320 330 340 612 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 22:13:04 2016 done: Wed Nov 2 22:13:04 2016 Total Scan time: 2.760 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]