FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1966, 727 aa 1>>>pF1KA1966 727 - 727 aa - 727 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.4365+/-0.00125; mu= -4.3795+/- 0.077 mean_var=466.2360+/-92.145, 0's: 0 Z-trim(114.8): 60 B-trim: 0 in 0/53 Lambda= 0.059398 statistics sampled from 15340 (15385) to 15340 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.755), E-opt: 0.2 (0.473), width: 16 Scan time: 4.650 The best scores are: opt bits E(32554) CCDS33992.1 YTHDC1 gene_id:91746|Hs108|chr4 ( 727) 4947 438.8 1.4e-122 CCDS82929.1 YTHDC1 gene_id:91746|Hs108|chr4 ( 735) 4921 436.5 6.7e-122 CCDS3522.2 YTHDC1 gene_id:91746|Hs108|chr4 ( 709) 3024 274.0 5.7e-73 >>CCDS33992.1 YTHDC1 gene_id:91746|Hs108|chr4 (727 aa) initn: 4947 init1: 4947 opt: 4947 Z-score: 2314.0 bits: 438.8 E(32554): 1.4e-122 Smith-Waterman score: 4947; 100.0% identity (100.0% similar) in 727 aa overlap (1-727:1-727) 10 20 30 40 50 60 pF1KA1 MAADSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MAADSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 KPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 ASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 ASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 SDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 SDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 EEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 EEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 RKRARGISPIVFDRSGSSASESYAGSEKKHEKLSSSVRAVRKDQTSKLKYVLQDARFFLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 RKRARGISPIVFDRSGSSASESYAGSEKKHEKLSSSVRAVRKDQTSKLKYVLQDARFFLI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 KSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 HGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 HGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ELECGTQLCLLFPPDESIDLYQVIHKMRHKRRMHSQPRSRGRPSRREPVRDVGRRRPEDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 ELECGTQLCLLFPPDESIDLYQVIHKMRHKRRMHSQPRSRGRPSRREPVRDVGRRRPEDY 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 DIHNSRKKPRIDYPPEFHQRPGYLKDPRYQEVDRRFSGVRRDVFLNGSYNDYVREFHNMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 DIHNSRKKPRIDYPPEFHQRPGYLKDPRYQEVDRRFSGVRRDVFLNGSYNDYVREFHNMG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 PPPPWQGMPPYPGMEQPPHHPYYQHHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 PPPPWQGMPPYPGMEQPPHHPYYQHHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 DDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 DDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRG 670 680 690 700 710 720 pF1KA1 ERGRYRR ::::::: CCDS33 ERGRYRR >>CCDS82929.1 YTHDC1 gene_id:91746|Hs108|chr4 (735 aa) initn: 4089 init1: 3857 opt: 4921 Z-score: 2301.9 bits: 436.5 E(32554): 6.7e-122 Smith-Waterman score: 4921; 98.9% identity (98.9% similar) in 735 aa overlap (1-727:1-735) 10 20 30 40 50 60 pF1KA1 MAADSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 MAADSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 KPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 ASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 ASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 SDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 SDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 EEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 EEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 RKRARGISPIVFDRSGSSASESYAGSEKKHEKLSSSVRAVRKDQTSKLKYVLQDARFFLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 RKRARGISPIVFDRSGSSASESYAGSEKKHEKLSSSVRAVRKDQTSKLKYVLQDARFFLI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 KSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 HGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 HGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ELECGTQLCLLFPPDESIDLYQVIHKMRHKRRMHSQPRSRGRPSRREPVRDVGRRRPEDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 ELECGTQLCLLFPPDESIDLYQVIHKMRHKRRMHSQPRSRGRPSRREPVRDVGRRRPEDY 490 500 510 520 530 540 550 560 570 580 590 pF1KA1 DIHNSRKKPRIDYPPEFHQRPGYLKDPRYQEVD--------RRFSGVRRDVFLNGSYNDY ::::::::::::::::::::::::::::::::: ::::::::::::::::::: CCDS82 DIHNSRKKPRIDYPPEFHQRPGYLKDPRYQEVDSFTNLIPNRRFSGVRRDVFLNGSYNDY 550 560 570 580 590 600 600 610 620 630 640 650 pF1KA1 VREFHNMGPPPPWQGMPPYPGMEQPPHHPYYQHHAPPPQAHPPYSGHHPVPHEARYRDKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 VREFHNMGPPPPWQGMPPYPGMEQPPHHPYYQHHAPPPQAHPPYSGHHPVPHEARYRDKR 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA1 VHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 VHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERL 670 680 690 700 710 720 720 pF1KA1 CDRDRDRGERGRYRR ::::::::::::::: CCDS82 CDRDRDRGERGRYRR 730 >>CCDS3522.2 YTHDC1 gene_id:91746|Hs108|chr4 (709 aa) initn: 2860 init1: 2860 opt: 3024 Z-score: 1423.6 bits: 274.0 E(32554): 5.7e-73 Smith-Waterman score: 4793; 97.5% identity (97.5% similar) in 727 aa overlap (1-727:1-709) 10 20 30 40 50 60 pF1KA1 MAADSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 MAADSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 KPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 ASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 ASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 SDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 SDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 EEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 EEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 RKRARGISPIVFDRSGSSASESYAGSEKKHEKLSSSVRAVRKDQTSKLKYVLQDARFFLI :::::::::::::::::::::::: :::::::::::::::::: CCDS35 RKRARGISPIVFDRSGSSASESYA------------------DQTSKLKYVLQDARFFLI 310 320 330 340 370 380 390 400 410 420 pF1KA1 KSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 KSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESH 350 360 370 380 390 400 430 440 450 460 470 480 pF1KA1 HGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 HGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEI 410 420 430 440 450 460 490 500 510 520 530 540 pF1KA1 ELECGTQLCLLFPPDESIDLYQVIHKMRHKRRMHSQPRSRGRPSRREPVRDVGRRRPEDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 ELECGTQLCLLFPPDESIDLYQVIHKMRHKRRMHSQPRSRGRPSRREPVRDVGRRRPEDY 470 480 490 500 510 520 550 560 570 580 590 600 pF1KA1 DIHNSRKKPRIDYPPEFHQRPGYLKDPRYQEVDRRFSGVRRDVFLNGSYNDYVREFHNMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 DIHNSRKKPRIDYPPEFHQRPGYLKDPRYQEVDRRFSGVRRDVFLNGSYNDYVREFHNMG 530 540 550 560 570 580 610 620 630 640 650 660 pF1KA1 PPPPWQGMPPYPGMEQPPHHPYYQHHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 PPPPWQGMPPYPGMEQPPHHPYYQHHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRV 590 600 610 620 630 640 670 680 690 700 710 720 pF1KA1 DDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 DDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRG 650 660 670 680 690 700 pF1KA1 ERGRYRR ::::::: CCDS35 ERGRYRR 727 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 22:19:43 2016 done: Wed Nov 2 22:19:43 2016 Total Scan time: 4.650 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]