Result of FASTA (omim) for
pF1KA2014
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA2014, 1027 aa
1>>>pF1KA2014 1027 - 1027 aa - 1027 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.9722+/-0.000455; mu= -0.0307+/- 0.029
mean_var=459.1704+/-92.926, 0's: 0 Z-trim(122.4): 89 B-trim: 151 in 1/61
Lambda= 0.059853
statistics sampled from 40407 (40503) to 40407 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.746), E-opt: 0.2 (0.475), width: 16
Scan time: 15.450
The best scores are: opt bits E(85289)
NP_783863 (OMIM: 616288) formin-like protein 3 iso (1027) 6765 599.5 3.1e-170
XP_005269275 (OMIM: 616288) PREDICTED: formin-like (1028) 6559 581.7 6.9e-165
XP_011537271 (OMIM: 616288) PREDICTED: formin-like (1046) 6475 574.5 1.1e-162
XP_011537273 (OMIM: 616288) PREDICTED: formin-like (1000) 6271 556.8 2.1e-157
XP_011537270 (OMIM: 616288) PREDICTED: formin-like (1047) 6269 556.7 2.4e-157
XP_011537276 (OMIM: 616288) PREDICTED: formin-like (1003) 6263 556.1 3.4e-157
XP_011537272 (OMIM: 616288) PREDICTED: formin-like (1046) 6245 554.6 1e-156
XP_011537275 (OMIM: 616288) PREDICTED: formin-like ( 925) 5530 492.8 3.6e-138
NP_944489 (OMIM: 616288) formin-like protein 3 iso ( 976) 5401 481.7 8.4e-135
XP_011537274 (OMIM: 616288) PREDICTED: formin-like ( 996) 5195 463.9 1.9e-129
XP_011508836 (OMIM: 616285) PREDICTED: formin-like (1076) 2478 229.3 8.6e-59
XP_005246322 (OMIM: 616285) PREDICTED: formin-like (1084) 2478 229.3 8.6e-59
XP_005246320 (OMIM: 616285) PREDICTED: formin-like (1087) 2478 229.4 8.7e-59
XP_011508835 (OMIM: 616285) PREDICTED: formin-like (1091) 2478 229.4 8.7e-59
NP_443137 (OMIM: 616285) formin-like protein 2 [Ho (1092) 2478 229.4 8.7e-59
XP_011508834 (OMIM: 616285) PREDICTED: formin-like (1093) 2478 229.4 8.7e-59
XP_011508833 (OMIM: 616285) PREDICTED: formin-like (1094) 2478 229.4 8.7e-59
XP_011508832 (OMIM: 616285) PREDICTED: formin-like (1099) 2478 229.4 8.7e-59
XP_011508838 (OMIM: 616285) PREDICTED: formin-like ( 860) 2345 217.8 2.1e-55
XP_011508837 (OMIM: 616285) PREDICTED: formin-like (1048) 2345 217.8 2.4e-55
XP_006722133 (OMIM: 604656) PREDICTED: formin-like (1104) 1870 176.9 5.6e-43
XP_006722129 (OMIM: 604656) PREDICTED: formin-like (1110) 1870 176.9 5.6e-43
NP_005883 (OMIM: 604656) formin-like protein 1 [Ho (1100) 1838 174.1 3.8e-42
XP_011523484 (OMIM: 604656) PREDICTED: formin-like (1106) 1838 174.1 3.8e-42
XP_011523482 (OMIM: 604656) PREDICTED: formin-like (1133) 1830 173.4 6.2e-42
XP_006722128 (OMIM: 604656) PREDICTED: formin-like (1148) 1830 173.4 6.3e-42
XP_006722127 (OMIM: 604656) PREDICTED: formin-like (1154) 1830 173.4 6.3e-42
XP_006722126 (OMIM: 604656) PREDICTED: formin-like (1158) 1830 173.4 6.3e-42
XP_011523481 (OMIM: 604656) PREDICTED: formin-like (1164) 1830 173.4 6.3e-42
XP_006722125 (OMIM: 604656) PREDICTED: formin-like (1164) 1830 173.4 6.3e-42
XP_006722132 (OMIM: 604656) PREDICTED: formin-like (1076) 1547 149.0 1.4e-34
NP_056160 (OMIM: 606627) disheveled-associated act (1067) 977 99.7 8.9e-20
NP_001188356 (OMIM: 606627) disheveled-associated (1068) 868 90.3 6.1e-17
XP_006715103 (OMIM: 606627) PREDICTED: disheveled- (1167) 868 90.4 6.4e-17
NP_001257449 (OMIM: 606626) disheveled-associated (1068) 864 90.0 7.7e-17
XP_006715108 (OMIM: 606627) PREDICTED: disheveled- (1077) 862 89.8 8.7e-17
XP_006715109 (OMIM: 606627) PREDICTED: disheveled- (1077) 862 89.8 8.7e-17
XP_006715106 (OMIM: 606627) PREDICTED: disheveled- (1077) 862 89.8 8.7e-17
XP_006715105 (OMIM: 606627) PREDICTED: disheveled- (1077) 862 89.8 8.7e-17
XP_016866119 (OMIM: 606627) PREDICTED: disheveled- (1100) 862 89.8 8.8e-17
XP_006715102 (OMIM: 606627) PREDICTED: disheveled- (1176) 862 89.8 9.2e-17
XP_005267487 (OMIM: 606626) PREDICTED: disheveled- (1078) 835 87.5 4.4e-16
NP_055807 (OMIM: 606626) disheveled-associated act (1078) 835 87.5 4.4e-16
XP_005267488 (OMIM: 606626) PREDICTED: disheveled- (1078) 835 87.5 4.4e-16
NP_112194 (OMIM: 609129,614567) protein diaphanous ( 849) 681 74.1 3.8e-12
XP_006719939 (OMIM: 609129,614567) PREDICTED: prot ( 930) 681 74.1 4e-12
NP_001245298 (OMIM: 609129,614567) protein diaphan (1112) 681 74.2 4.5e-12
NP_001245297 (OMIM: 609129,614567) protein diaphan (1123) 681 74.2 4.5e-12
XP_011533560 (OMIM: 609129,614567) PREDICTED: prot (1136) 681 74.2 4.6e-12
NP_001245296 (OMIM: 609129,614567) protein diaphan (1147) 681 74.2 4.6e-12
>>NP_783863 (OMIM: 616288) formin-like protein 3 isoform (1027 aa)
initn: 6765 init1: 6765 opt: 6765 Z-score: 3177.4 bits: 599.5 E(85289): 3.1e-170
Smith-Waterman score: 6765; 100.0% identity (100.0% similar) in 1027 aa overlap (1-1027:1-1027)
10 20 30 40 50 60
pF1KA2 MGNLESAEGVPGEPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNLPPDKARLLRQYDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 MGNLESAEGVPGEPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNLPPDKARLLRQYDN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA2 EKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 EKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA2 HIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 HIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA2 PSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 PSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA2 FNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 FNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA2 HRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 HRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA2 HTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 HTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA2 MRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 MRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLES
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA2 VDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 VDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA2 PPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 PPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILED
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA2 LDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 LDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA2 ICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 ICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA2 ERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 ERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA2 KRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 KRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA2 LENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 LENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA2 YFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 YFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA2 QRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVVRHQARSAAPPSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 QRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVVRHQARSAAPPSGP
970 980 990 1000 1010 1020
pF1KA2 PRAPGPH
:::::::
NP_783 PRAPGPH
>>XP_005269275 (OMIM: 616288) PREDICTED: formin-like pro (1028 aa)
initn: 6682 init1: 6559 opt: 6559 Z-score: 3081.2 bits: 581.7 E(85289): 6.9e-165
Smith-Waterman score: 6559; 98.8% identity (99.4% similar) in 1014 aa overlap (1-1014:1-1014)
10 20 30 40 50 60
pF1KA2 MGNLESAEGVPGEPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNLPPDKARLLRQYDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGNLESAEGVPGEPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNLPPDKARLLRQYDN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA2 EKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA2 HIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA2 PSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA2 FNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA2 HRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA2 HTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA2 MRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLES
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA2 VDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA2 PPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILED
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA2 LDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA2 ICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA2 ERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA2 KRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA2 LENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA2 YFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA2 QRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVVRHQARSAAPPSGP
:::::::::::::::::::::::::::::::::::::: :. :...: :..
XP_005 QRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITVLKSVPFTARTAKRGSRFFCDA
970 980 990 1000 1010 1020
pF1KA2 PRAPGPH
XP_005 AHHDESNC
>>XP_011537271 (OMIM: 616288) PREDICTED: formin-like pro (1046 aa)
initn: 6469 init1: 6469 opt: 6475 Z-score: 3041.9 bits: 574.5 E(85289): 1.1e-162
Smith-Waterman score: 6475; 98.1% identity (98.5% similar) in 1010 aa overlap (18-1027:45-1046)
10 20 30 40
pF1KA2 MGNLESAEGVPGEPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNL
: .: :. .: : .: :::::
XP_011 LKEGPQCSKGKWCRWHLSARQLCEGPKGCGPYILWPSAFP---PASSGDR-----SSMNL
20 30 40 50 60
50 60 70 80 90 100
pF1KA2 PPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQEST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQEST
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA2 KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA2 LRSWSRSIEDLQPPSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRSWSRSIEDLQPPSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVC
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA2 ILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIIL
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA2 AAFDNFKEVCKELHRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAFDNFKEVCKELHRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEF
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA2 TKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSH
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA2 LTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQR
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA2 RCHLEPNVRGLESVDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCHLEPNVRGLESVDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLP
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA2 PPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGT
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA2 VFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNL
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA2 AITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEEL
670 680 690 700 710 720
710 720 730 740 750 760
pF1KA2 AAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQML
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA2 EIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFW
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA2 HELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRD
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA2 AKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQL
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA2 AQEAKKLDAKTPSQRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQEAKKLDAKTPSQRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVV
970 980 990 1000 1010 1020
1010 1020
pF1KA2 RHQARSAAPPSGPPRAPGPH
::::::::::::::::::::
XP_011 RHQARSAAPPSGPPRAPGPH
1030 1040
>>XP_011537273 (OMIM: 616288) PREDICTED: formin-like pro (1000 aa)
initn: 6391 init1: 6268 opt: 6271 Z-score: 2947.0 bits: 556.8 E(85289): 2.1e-157
Smith-Waterman score: 6271; 98.1% identity (99.0% similar) in 983 aa overlap (34-1014:4-986)
10 20 30 40 50 60
pF1KA2 LESAEGVPGEPPSVPLLLPPGKMPMPEPCELEERF--ALVLSSMNLPPDKARLLRQYDNE
:. .: : .::::::::::::::::::::
XP_011 MFALKMKFCRAKTLSSMNLPPDKARLLRQYDNE
10 20 30
70 80 90 100 110 120
pF1KA2 KKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTNH
40 50 60 70 80 90
130 140 150 160 170 180
pF1KA2 IGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQPP
100 110 120 130 140 150
190 200 210 220 230 240
pF1KA2 SALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYGF
160 170 180 190 200 210
250 260 270 280 290 300
pF1KA2 NLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKELH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKELH
220 230 240 250 260 270
310 320 330 340 350 360
pF1KA2 RFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRH
280 290 300 310 320 330
370 380 390 400 410 420
pF1KA2 TESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENMM
340 350 360 370 380 390
430 440 450 460 470 480
pF1KA2 RVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLESV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLESV
400 410 420 430 440 450
490 500 510 520 530 540
pF1KA2 DSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPAP
460 470 480 490 500 510
550 560 570 580 590 600
pF1KA2 PLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILEDL
520 530 540 550 560 570
610 620 630 640 650 660
pF1KA2 DLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEI
580 590 600 610 620 630
670 680 690 700 710 720
pF1KA2 CRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVE
640 650 660 670 680 690
730 740 750 760 770 780
pF1KA2 RLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSK
700 710 720 730 740 750
790 800 810 820 830 840
pF1KA2 RGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSL
760 770 780 790 800 810
850 860 870 880 890 900
pF1KA2 ENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRY
820 830 840 850 860 870
910 920 930 940 950 960
pF1KA2 FGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQ
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KA2 RNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVVRHQARSAAPPSGPP
::::::::::::::::::::::::::::::::::::: :. :...: :..
XP_011 RNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITVLKSVPFTARTAKRGSRFFCDAA
940 950 960 970 980 990
pF1KA2 RAPGPH
XP_011 HHDESNC
1000
>>XP_011537270 (OMIM: 616288) PREDICTED: formin-like pro (1047 aa)
initn: 6386 init1: 6263 opt: 6269 Z-score: 2945.8 bits: 556.7 E(85289): 2.4e-157
Smith-Waterman score: 6269; 96.9% identity (97.9% similar) in 997 aa overlap (18-1014:45-1033)
10 20 30 40
pF1KA2 MGNLESAEGVPGEPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNL
: .: :. .: : .: :::::
XP_011 LKEGPQCSKGKWCRWHLSARQLCEGPKGCGPYILWPSAFP---PASSGDR-----SSMNL
20 30 40 50 60
50 60 70 80 90 100
pF1KA2 PPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQEST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQEST
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA2 KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA2 LRSWSRSIEDLQPPSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRSWSRSIEDLQPPSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVC
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA2 ILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIIL
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA2 AAFDNFKEVCKELHRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAFDNFKEVCKELHRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEF
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA2 TKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSH
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA2 LTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQR
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA2 RCHLEPNVRGLESVDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCHLEPNVRGLESVDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLP
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA2 PPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGT
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA2 VFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNL
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA2 AITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEEL
670 680 690 700 710 720
710 720 730 740 750 760
pF1KA2 AAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQML
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA2 EIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFW
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA2 HELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRD
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA2 AKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQL
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA2 AQEAKKLDAKTPSQRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVV
::::::::::::::::::::::::::::::::::::::::::::::::::: :. :...
XP_011 AQEAKKLDAKTPSQRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITVLKSVPFTA
970 980 990 1000 1010 1020
1010 1020
pF1KA2 RHQARSAAPPSGPPRAPGPH
: :..
XP_011 RTAKRGSRFFCDAAHHDESNC
1030 1040
>>XP_011537276 (OMIM: 616288) PREDICTED: formin-like pro (1003 aa)
initn: 6386 init1: 6263 opt: 6263 Z-score: 2943.2 bits: 556.1 E(85289): 3.4e-157
Smith-Waterman score: 6263; 98.8% identity (99.4% similar) in 972 aa overlap (43-1014:18-989)
20 30 40 50 60 70
pF1KA2 EPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNLPPDKARLLRQYDNEKKWDLICDQER
::::::::::::::::::::::::::::::
XP_011 MHTVHVPRDEDAKNWAESSMNLPPDKARLLRQYDNEKKWDLICDQER
10 20 30 40
80 90 100 110 120 130
pF1KA2 FQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTNHIGWVREFLNDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTNHIGWVREFLNDE
50 60 70 80 90 100
140 150 160 170 180 190
pF1KA2 NKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQPPSALSAPFTNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQPPSALSAPFTNSL
110 120 130 140 150 160
200 210 220 230 240 250
pF1KA2 ARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYGFNLVMSHPHAVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYGFNLVMSHPHAVN
170 180 190 200 210 220
260 270 280 290 300 310
pF1KA2 EIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKELHRFEKLMEYFRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKELHRFEKLMEYFRN
230 240 250 260 270 280
320 330 340 350 360 370
pF1KA2 EDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRHTESEKLQVQIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRHTESEKLQVQIQ
290 300 310 320 330 340
380 390 400 410 420 430
pF1KA2 AYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENMMRVAELEKQLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENMMRVAELEKQLLQ
350 360 370 380 390 400
440 450 460 470 480 490
pF1KA2 REKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLESVDSEALARVGPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLESVDSEALARVGPA
410 420 430 440 450 460
500 510 520 530 540 550
pF1KA2 ELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPAPPLPGAAPSVVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPAPPLPGAAPSVVL
470 480 490 500 510 520
560 570 580 590 600 610
pF1KA2 TVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILEDLDLDKFEELFKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILEDLDLDKFEELFKT
530 540 550 560 570 580
620 630 640 650 660 670
pF1KA2 KAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQT
590 600 610 620 630 640
680 690 700 710 720 730
pF1KA2 LPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAF
650 660 670 680 690 700
740 750 760 770 780 790
pF1KA2 LGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQS
710 720 730 740 750 760
800 810 820 830 840 850
pF1KA2 LDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELG
770 780 790 800 810 820
860 870 880 890 900 910
pF1KA2 RGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPS
830 840 850 860 870 880
920 930 940 950 960 970
pF1KA2 VFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQQQELIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQQQELIA
890 900 910 920 930 940
980 990 1000 1010 1020
pF1KA2 ELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVVRHQARSAAPPSGPPRAPGPH
:::::::::::::::::::::::::: :. :...: :..
XP_011 ELRRRQAKEHRPVYEGKDGTIEDIITVLKSVPFTARTAKRGSRFFCDAAHHDESNC
950 960 970 980 990 1000
>>XP_011537272 (OMIM: 616288) PREDICTED: formin-like pro (1046 aa)
initn: 6366 init1: 4158 opt: 6245 Z-score: 2934.6 bits: 554.6 E(85289): 1e-156
Smith-Waterman score: 6251; 96.8% identity (97.8% similar) in 997 aa overlap (18-1014:45-1032)
10 20 30 40
pF1KA2 MGNLESAEGVPGEPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNL
: .: :. .: : .: :::::
XP_011 LKEGPQCSKGKWCRWHLSARQLCEGPKGCGPYILWPSAFP---PASSGDR-----SSMNL
20 30 40 50 60
50 60 70 80 90 100
pF1KA2 PPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQEST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQEST
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA2 KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA2 LRSWSRSIEDLQPPSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRSWSRSIEDLQPPSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVC
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA2 ILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIIL
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA2 AAFDNFKEVCKELHRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAFDNFKEVCKELHRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEF
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA2 TKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSH
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKLGLEEFLQ-SRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSH
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA2 LTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQR
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA2 RCHLEPNVRGLESVDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCHLEPNVRGLESVDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLP
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA2 PPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGT
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA2 VFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNL
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA2 AITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEEL
670 680 690 700 710 720
710 720 730 740 750 760
pF1KA2 AAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQML
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA2 EIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFW
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA2 HELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRD
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA2 AKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQL
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA2 AQEAKKLDAKTPSQRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVV
::::::::::::::::::::::::::::::::::::::::::::::::::: :. :...
XP_011 AQEAKKLDAKTPSQRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITVLKSVPFTA
970 980 990 1000 1010 1020
1010 1020
pF1KA2 RHQARSAAPPSGPPRAPGPH
: :..
XP_011 RTAKRGSRFFCDAAHHDESNC
1030 1040
>>XP_011537275 (OMIM: 616288) PREDICTED: formin-like pro (925 aa)
initn: 5650 init1: 5527 opt: 5530 Z-score: 2601.6 bits: 492.8 E(85289): 3.6e-138
Smith-Waterman score: 5530; 98.5% identity (99.3% similar) in 864 aa overlap (151-1014:48-911)
130 140 150 160 170 180
pF1KA2 HIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQP
.:::::::::::::::::::::::::::::
XP_011 DLHGGRGQEGGEGLFLRGVYPEVRMIREESLFDFEGLESGDDGAFDKLRSWSRSIEDLQP
20 30 40 50 60 70
190 200 210 220 230 240
pF1KA2 PSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYG
80 90 100 110 120 130
250 260 270 280 290 300
pF1KA2 FNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKEL
140 150 160 170 180 190
310 320 330 340 350 360
pF1KA2 HRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSR
200 210 220 230 240 250
370 380 390 400 410 420
pF1KA2 HTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENM
260 270 280 290 300 310
430 440 450 460 470 480
pF1KA2 MRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLES
320 330 340 350 360 370
490 500 510 520 530 540
pF1KA2 VDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPA
380 390 400 410 420 430
550 560 570 580 590 600
pF1KA2 PPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILED
440 450 460 470 480 490
610 620 630 640 650 660
pF1KA2 LDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEE
500 510 520 530 540 550
670 680 690 700 710 720
pF1KA2 ICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKV
560 570 580 590 600 610
730 740 750 760 770 780
pF1KA2 ERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSS
620 630 640 650 660 670
790 800 810 820 830 840
pF1KA2 KRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVS
680 690 700 710 720 730
850 860 870 880 890 900
pF1KA2 LENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVR
740 750 760 770 780 790
910 920 930 940 950 960
pF1KA2 YFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPS
800 810 820 830 840 850
970 980 990 1000 1010 1020
pF1KA2 QRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVVRHQARSAAPPSGP
:::::::::::::::::::::::::::::::::::::: :. :...: :..
XP_011 QRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITVLKSVPFTARTAKRGSRFFCDA
860 870 880 890 900 910
pF1KA2 PRAPGPH
XP_011 AHHDESNC
920
>>NP_944489 (OMIM: 616288) formin-like protein 3 isoform (976 aa)
initn: 5400 init1: 5400 opt: 5401 Z-score: 2541.1 bits: 481.7 E(85289): 8.4e-135
Smith-Waterman score: 6317; 95.0% identity (95.0% similar) in 1027 aa overlap (1-1027:1-976)
10 20 30 40 50 60
pF1KA2 MGNLESAEGVPGEPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNLPPDKARLLRQYDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 MGNLESAEGVPGEPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNLPPDKARLLRQYDN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA2 EKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 EKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA2 HIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQP
:::::::::::::::::::::::::::::::
NP_944 HIGWVREFLNDENKGLDVLVDYLSFAQCSVM-----------------------------
130 140 150
190 200 210 220 230 240
pF1KA2 PSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYG
::::::::::::::::::::::::::::::::::::::
NP_944 ----------------------YSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYG
160 170 180
250 260 270 280 290 300
pF1KA2 FNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 FNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKEL
190 200 210 220 230 240
310 320 330 340 350 360
pF1KA2 HRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 HRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSR
250 260 270 280 290 300
370 380 390 400 410 420
pF1KA2 HTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 HTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENM
310 320 330 340 350 360
430 440 450 460 470 480
pF1KA2 MRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 MRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLES
370 380 390 400 410 420
490 500 510 520 530 540
pF1KA2 VDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 VDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPA
430 440 450 460 470 480
550 560 570 580 590 600
pF1KA2 PPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 PPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILED
490 500 510 520 530 540
610 620 630 640 650 660
pF1KA2 LDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 LDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEE
550 560 570 580 590 600
670 680 690 700 710 720
pF1KA2 ICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 ICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKV
610 620 630 640 650 660
730 740 750 760 770 780
pF1KA2 ERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 ERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSS
670 680 690 700 710 720
790 800 810 820 830 840
pF1KA2 KRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 KRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVS
730 740 750 760 770 780
850 860 870 880 890 900
pF1KA2 LENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 LENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVR
790 800 810 820 830 840
910 920 930 940 950 960
pF1KA2 YFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 YFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPS
850 860 870 880 890 900
970 980 990 1000 1010 1020
pF1KA2 QRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVVRHQARSAAPPSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 QRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVVRHQARSAAPPSGP
910 920 930 940 950 960
pF1KA2 PRAPGPH
:::::::
NP_944 PRAPGPH
970
>>XP_011537274 (OMIM: 616288) PREDICTED: formin-like pro (996 aa)
initn: 6040 init1: 5191 opt: 5195 Z-score: 2444.8 bits: 463.9 E(85289): 1.9e-129
Smith-Waterman score: 5821; 91.8% identity (92.8% similar) in 997 aa overlap (18-1014:45-982)
10 20 30 40
pF1KA2 MGNLESAEGVPGEPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNL
: .: :. .: : .: :::::
XP_011 LKEGPQCSKGKWCRWHLSARQLCEGPKGCGPYILWPSAFP---PASSGDR-----SSMNL
20 30 40 50 60
50 60 70 80 90 100
pF1KA2 PPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQEST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQEST
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA2 KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDK
::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVM----------------
130 140 150 160 170
170 180 190 200 210 220
pF1KA2 LRSWSRSIEDLQPPSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVC
:::::::::::::::::::::::::
XP_011 -----------------------------------YSTLPGRRALKNSRLVSQKDDVHVC
180 190
230 240 250 260 270 280
pF1KA2 ILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIIL
200 210 220 230 240 250
290 300 310 320 330 340
pF1KA2 AAFDNFKEVCKELHRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAFDNFKEVCKELHRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEF
260 270 280 290 300 310
350 360 370 380 390 400
pF1KA2 TKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSH
320 330 340 350 360 370
410 420 430 440 450 460
pF1KA2 LTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQR
380 390 400 410 420 430
470 480 490 500 510 520
pF1KA2 RCHLEPNVRGLESVDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCHLEPNVRGLESVDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLP
440 450 460 470 480 490
530 540 550 560 570 580
pF1KA2 PPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGT
500 510 520 530 540 550
590 600 610 620 630 640
pF1KA2 VFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNL
560 570 580 590 600 610
650 660 670 680 690 700
pF1KA2 AITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEEL
620 630 640 650 660 670
710 720 730 740 750 760
pF1KA2 AAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQML
680 690 700 710 720 730
770 780 790 800 810 820
pF1KA2 EIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFW
740 750 760 770 780 790
830 840 850 860 870 880
pF1KA2 HELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRD
800 810 820 830 840 850
890 900 910 920 930 940
pF1KA2 AKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQL
860 870 880 890 900 910
950 960 970 980 990 1000
pF1KA2 AQEAKKLDAKTPSQRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVV
::::::::::::::::::::::::::::::::::::::::::::::::::: :. :...
XP_011 AQEAKKLDAKTPSQRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITVLKSVPFTA
920 930 940 950 960 970
1010 1020
pF1KA2 RHQARSAAPPSGPPRAPGPH
: :..
XP_011 RTAKRGSRFFCDAAHHDESNC
980 990
1027 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 20:16:41 2016 done: Thu Nov 3 20:16:43 2016
Total Scan time: 15.450 Total Display time: 0.490
Function used was FASTA [36.3.4 Apr, 2011]