Result of FASTA (omim) for
pF1KB0001
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0001, 2511 aa
1>>>pF1KB0001 2511 - 2511 aa - 2511 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3608+/-0.000417; mu= 21.2087+/- 0.026
mean_var=91.8123+/-19.111, 0's: 0 Z-trim(112.6): 58 B-trim: 320 in 1/52
Lambda= 0.133852
statistics sampled from 21520 (21578) to 21520 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.58), E-opt: 0.2 (0.253), width: 16
Scan time: 21.520
The best scores are: opt bits E(85289)
XP_011521840 (OMIM: 600212) PREDICTED: fatty acid (2511) 16719 3240.2 0
NP_004095 (OMIM: 600212) fatty acid synthase [Homo (2511) 16719 3240.2 0
XP_016862202 (OMIM: 610324) PREDICTED: 3-oxoacyl-[ ( 459) 403 89.2 1.4e-16
NP_060367 (OMIM: 610324) 3-oxoacyl-[acyl-carrier-p ( 459) 403 89.2 1.4e-16
XP_006713279 (OMIM: 610324) PREDICTED: 3-oxoacyl-[ ( 459) 403 89.2 1.4e-16
NP_004872 (OMIM: 605171) quinone oxidoreductase PI ( 332) 347 78.3 2e-13
NP_671713 (OMIM: 605171) quinone oxidoreductase PI ( 332) 347 78.3 2e-13
XP_011539049 (OMIM: 123691) PREDICTED: quinone oxi ( 329) 250 59.5 8.4e-08
NP_001123514 (OMIM: 123691) quinone oxidoreductase ( 329) 250 59.5 8.4e-08
NP_001880 (OMIM: 123691) quinone oxidoreductase is ( 329) 250 59.5 8.4e-08
NP_006364 (OMIM: 604631) synaptic vesicle membrane ( 393) 231 55.9 1.2e-06
NP_001193731 (OMIM: 605171) quinone oxidoreductase ( 248) 224 54.5 2.2e-06
XP_006712213 (OMIM: 605171) PREDICTED: quinone oxi ( 248) 224 54.5 2.2e-06
XP_005264707 (OMIM: 605171) PREDICTED: quinone oxi ( 243) 217 53.1 5.4e-06
XP_006713280 (OMIM: 610324) PREDICTED: 3-oxoacyl-[ ( 184) 206 50.9 1.9e-05
XP_016862203 (OMIM: 610324) PREDICTED: 3-oxoacyl-[ ( 184) 206 50.9 1.9e-05
NP_001028839 (OMIM: 600684) T-lymphocyte surface a ( 193) 202 50.1 3.3e-05
XP_005270548 (OMIM: 123691) PREDICTED: quinone oxi ( 192) 187 47.3 0.00025
NP_001128231 (OMIM: 123691) quinone oxidoreductase ( 192) 187 47.3 0.00025
XP_016855857 (OMIM: 123691) PREDICTED: quinone oxi ( 192) 187 47.3 0.00025
XP_016855856 (OMIM: 123691) PREDICTED: quinone oxi ( 295) 187 47.3 0.00035
NP_001123515 (OMIM: 123691) quinone oxidoreductase ( 295) 187 47.3 0.00035
NP_001019903 (OMIM: 608205) trans-2-enoyl-CoA redu ( 297) 186 47.2 0.00041
NP_057095 (OMIM: 608205) trans-2-enoyl-CoA reducta ( 373) 186 47.2 0.00049
NP_001138863 (OMIM: 610324) 3-oxoacyl-[acyl-carrie ( 376) 186 47.2 0.0005
XP_005245944 (OMIM: 608205) PREDICTED: trans-2-eno ( 297) 183 46.6 0.00061
XP_016856903 (OMIM: 608205) PREDICTED: trans-2-eno ( 297) 183 46.6 0.00061
XP_016856902 (OMIM: 608205) PREDICTED: trans-2-eno ( 297) 183 46.6 0.00061
XP_016856904 (OMIM: 608205) PREDICTED: trans-2-eno ( 297) 183 46.6 0.00061
XP_005245942 (OMIM: 608205) PREDICTED: trans-2-eno ( 401) 183 46.6 0.00078
XP_011516697 (OMIM: 601274) PREDICTED: prostagland ( 206) 175 44.9 0.0013
NP_036344 (OMIM: 601274) prostaglandin reductase 1 ( 329) 175 45.1 0.0019
NP_001139580 (OMIM: 601274) prostaglandin reductas ( 329) 175 45.1 0.0019
NP_665857 (OMIM: 603920) quinone oxidoreductase-li ( 349) 172 44.5 0.003
XP_016856905 (OMIM: 608205) PREDICTED: trans-2-eno ( 260) 167 43.5 0.0046
XP_011539843 (OMIM: 608205) PREDICTED: trans-2-eno ( 364) 167 43.5 0.0061
NP_000661 (OMIM: 103740) alcohol dehydrogenase 4 i ( 380) 166 43.3 0.0073
NP_001293100 (OMIM: 103740) alcohol dehydrogenase ( 399) 166 43.4 0.0076
NP_001293101 (OMIM: 103740) alcohol dehydrogenase ( 399) 166 43.4 0.0076
>>XP_011521840 (OMIM: 600212) PREDICTED: fatty acid synt (2511 aa)
initn: 16719 init1: 16719 opt: 16719 Z-score: 17435.2 bits: 3240.2 E(85289): 0
Smith-Waterman score: 16719; 100.0% identity (100.0% similar) in 2511 aa overlap (1-2511:1-2511)
10 20 30 40 50 60
pF1KB0 MEEVVIAGMSGKLPESENLQEFWDNLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEEVVIAGMSGKLPESENLQEFWDNLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 DASFFGVHPKQAHTMDPQLRLLLEVTYEAIVDGGINPDSLRGTHTGVWVGVSGSETSEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DASFFGVHPKQAHTMDPQLRLLLEVTYEAIVDGGINPDSLRGTHTGVWVGVSGSETSEAL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SRDPETLVGYSMVGCQRAMMANRLSFFFDFRGPSIALDTACSSSLMALQNAYQAIHSGQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRDPETLVGYSMVGCQRAMMANRLSFFFDFRGPSIALDTACSSSLMALQNAYQAIHSGQC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 PAAIVGGINVLLKPNTSVQFLRLGMLSPEGTCKAFDTAGNGYCRSEGVVAVLLTKKSLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAAIVGGINVLLKPNTSVQFLRLGMLSPEGTCKAFDTAGNGYCRSEGVVAVLLTKKSLAR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 RVYATILNAGTNTDGFKEQGVTFPSGDIQEQLIRSLYQSAGVAPESFEYIEAHGTGTKVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVYATILNAGTNTDGFKEQGVTFPSGDIQEQLIRSLYQSAGVAPESFEYIEAHGTGTKVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DPQELNGITRALCATRQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPQELNGITRALCATRQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 SPNPEIPALLDGRLQVVDQPLPVRGGNVGINSFGFGGSNVHIILRPNTQPPPAPAPHATL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPNPEIPALLDGRLQVVDQPLPVRGGNVGINSFGFGGSNVHIILRPNTQPPPAPAPHATL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 PRLLRASGRTPEAVQKLLEQGLRHSQDLAFLSMLNDIAAVPATAMPFRGYAVLGGERGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRLLRASGRTPEAVQKLLEQGLRHSQDLAFLSMLNDIAAVPATAMPFRGYAVLGGERGGP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 EVQQVPAGERPLWFICSGMGTQWRGMGLSLMRLDRFRDSILRSDEAVKPFGLKVSQLLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVQQVPAGERPLWFICSGMGTQWRGMGLSLMRLDRFRDSILRSDEAVKPFGLKVSQLLLS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 TDESTFDDIVHSFVSLTAIQIGLIDLLSCMGLRPDGIVGHSLGEVACGYADGCLSQEEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDESTFDDIVHSFVSLTAIQIGLIDLLSCMGLRPDGIVGHSLGEVACGYADGCLSQEEAV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 LAAYWRGQCIKEAHLPPGAMAAVGLSWEECKQRCPPGVVPACHNSKDTVTISGPQAPVFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAAYWRGQCIKEAHLPPGAMAAVGLSWEECKQRCPPGVVPACHNSKDTVTISGPQAPVFE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 FVEQLRKEGVFAKEVRTGGMAFHSYFMEAIAPPLLQELKKVIREPKPRSARWLSTSIPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVEQLRKEGVFAKEVRTGGMAFHSYFMEAIAPPLLQELKKVIREPKPRSARWLSTSIPEA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 QWHSSLARTSSAEYNVNNLVSPVLFQEALWHVPEHAVVLEIAPHALLQAVLKRGLKPSCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QWHSSLARTSSAEYNVNNLVSPVLFQEALWHVPEHAVVLEIAPHALLQAVLKRGLKPSCT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 IIPLMKKDHRDNLEFFLAGIGRLHLSGIDANPNALFPPVEFPAPRGTPLISPLIKWDHSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IIPLMKKDHRDNLEFFLAGIGRLHLSGIDANPNALFPPVEFPAPRGTPLISPLIKWDHSL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 AWDVPAAEDFPNGSGSPSAAIYNIDTSSESPDHYLVDHTLDGRVLFPATGYLSIVWKTLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AWDVPAAEDFPNGSGSPSAAIYNIDTSSESPDHYLVDHTLDGRVLFPATGYLSIVWKTLA
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 RALGLGVEQLPVVFEDVVLHQATILPKTGTVSLEVRLLEASRAFEVSENGNLVVSGKVYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RALGLGVEQLPVVFEDVVLHQATILPKTGTVSLEVRLLEASRAFEVSENGNLVVSGKVYQ
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 WDDPDPRLFDHPESPTPNPTEPLFLAQAEVYKELRLRGYDYGPHFQGILEASLEGDSGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WDDPDPRLFDHPESPTPNPTEPLFLAQAEVYKELRLRGYDYGPHFQGILEASLEGDSGRL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 LWKDNWVSFMDTMLQMSILGSAKHGLYLPTRVTAIHIDPATHRQKLYTLQDKAQVADVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LWKDNWVSFMDTMLQMSILGSAKHGLYLPTRVTAIHIDPATHRQKLYTLQDKAQVADVVV
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 SRWLRVTVAGGVHISGLHTESAPRRQQEQQVPILEKFCFTPHTEEGCLSERAALQEELQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRWLRVTVAGGVHISGLHTESAPRRQQEQQVPILEKFCFTPHTEEGCLSERAALQEELQL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 CKGLVQALQTKVTQQGLKMVVPGLDGAQIPRDPSQQELPRLLSAACRLQLNGNLQLELAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CKGLVQALQTKVTQQGLKMVVPGLDGAQIPRDPSQQELPRLLSAACRLQLNGNLQLELAQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 VLAQERPKLPEDPLLSGLLDSPALKACLDTAVENMPSLKMKVVEVLAGHGHLYSRIPGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLAQERPKLPEDPLLSGLLDSPALKACLDTAVENMPSLKMKVVEVLAGHGHLYSRIPGLL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 SPHPLLQLSYTATDRHPQALEAAQAELQQHDVAQGQWDPADPAPSALGSADLLVCNCAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPHPLLQLSYTATDRHPQALEAAQAELQQHDVAQGQWDPADPAPSALGSADLLVCNCAVA
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 ALGDPASALSNMVAALREGGFLLLHTLLRGHPLGDIVAFLTSTEPQYGQGILSQDAWESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALGDPASALSNMVAALREGGFLLLHTLLRGHPLGDIVAFLTSTEPQYGQGILSQDAWESL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 FSRVSLRLVGLKKSFYGSTLFLCRRPTPQDSPIFLPVDDTSFRWVESLKGILADEDSSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSRVSLRLVGLKKSFYGSTLFLCRRPTPQDSPIFLPVDDTSFRWVESLKGILADEDSSRP
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB0 VWLKAINCATSGVVGLVNCLRREPGGNRLRCVLLSNLSSTSHVPEVDPGSAELQKVLQGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VWLKAINCATSGVVGLVNCLRREPGGNRLRCVLLSNLSSTSHVPEVDPGSAELQKVLQGD
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB0 LVMNVYRDGAWGAFRHFLLEEDKPEEPTAHAFVSTLTRGDLSSIRWVCSSLRHAQPTCPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVMNVYRDGAWGAFRHFLLEEDKPEEPTAHAFVSTLTRGDLSSIRWVCSSLRHAQPTCPG
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB0 AQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFSGRDASGKRVMGLVPAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFSGRDASGKRVMGLVPAK
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB0 GLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGV
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KB0 GQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSFEQHVLWHTGGKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSFEQHVLWHTGGKG
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KB0 VDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGVLLDAFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGVLLDAFF
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KB0 NESSADWREVWALVQAGIRDGVVRPLKCTVFHGAQVEDAFRYMAQGKHIGKVVVQVLAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NESSADWREVWALVQAGIRDGVVRPLKCTVFHGAQVEDAFRYMAQGKHIGKVVVQVLAEE
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KB0 PEAVLKGAKPKLMSAISKTFCPAHKSYIIAGGLGGFGLELAQWLIQRGVQKLVLTSRSGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEAVLKGAKPKLMSAISKTFCPAHKSYIIAGGLGGFGLELAQWLIQRGVQKLVLTSRSGI
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KB0 RTGYQAKQVRRWRRQGVQVQVSTSNISSLEGARGLIAEAAQLGPVGGVFNLAVVLRDGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTGYQAKQVRRWRRQGVQVQVSTSNISSLEGARGLIAEAAQLGPVGGVFNLAVVLRDGLL
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KB0 ENQTPEFFQDVCKPKYSGTLNLDRVTREACPELDYFVVFSSVSCGRGNAGQSNYGFANSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENQTPEFFQDVCKPKYSGTLNLDRVTREACPELDYFVVFSSVSCGRGNAGQSNYGFANSA
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KB0 MERICEKRRHEGLPGLAVQWGAIGDVGILVETMSTNDTIVSGTLPQRMASCLEVLDLFLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MERICEKRRHEGLPGLAVQWGAIGDVGILVETMSTNDTIVSGTLPQRMASCLEVLDLFLN
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KB0 QPHMVLSSFVLAEKAAAYRDRDSQRDLVEAVAHILGIRDLAAVNLDSSLADLGLDSLMSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPHMVLSSFVLAEKAAAYRDRDSQRDLVEAVAHILGIRDLAAVNLDSSLADLGLDSLMSV
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KB0 EVRQTLERELNLVLSVREVRQLTLRKLQELSSKADEASELACPTPKEDGLAQQQTQLNLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVRQTLERELNLVLSVREVRQLTLRKLQELSSKADEASELACPTPKEDGLAQQQTQLNLR
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KB0 SLLVNPEGPTLMRLNSVQSSERPLFLVHPIEGSTTVFHSLASRLSIPTYGLQCTRAAPLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLLVNPEGPTLMRLNSVQSSERPLFLVHPIEGSTTVFHSLASRLSIPTYGLQCTRAAPLD
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KB0 SIHSLAAYYIDCIRQVQPEGPYRVAGYSYGACVAFEMCSQLQAQQSPAPTHNSLFLFDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIHSLAAYYIDCIRQVQPEGPYRVAGYSYGACVAFEMCSQLQAQQSPAPTHNSLFLFDGS
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KB0 PTYVLAYTQSYRAKLTPGCEAEAETEAICFFVQQFTDMEHNRVLEALLPLKGLEERVAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTYVLAYTQSYRAKLTPGCEAEAETEAICFFVQQFTDMEHNRVLEALLPLKGLEERVAAA
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KB0 VDLIIKSHQGLDRQELSFAARSFYYKLRAAEQYTPKAKYHGNVMLLRAKTGGAYGEDLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDLIIKSHQGLDRQELSFAARSFYYKLRAAEQYTPKAKYHGNVMLLRAKTGGAYGEDLGA
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510
pF1KB0 DYNLSQVCDGKVSVHVIEGDHRTLLEGSGLESIISIIHSSLAEPRVSVREG
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DYNLSQVCDGKVSVHVIEGDHRTLLEGSGLESIISIIHSSLAEPRVSVREG
2470 2480 2490 2500 2510
>>NP_004095 (OMIM: 600212) fatty acid synthase [Homo sap (2511 aa)
initn: 16719 init1: 16719 opt: 16719 Z-score: 17435.2 bits: 3240.2 E(85289): 0
Smith-Waterman score: 16719; 100.0% identity (100.0% similar) in 2511 aa overlap (1-2511:1-2511)
10 20 30 40 50 60
pF1KB0 MEEVVIAGMSGKLPESENLQEFWDNLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MEEVVIAGMSGKLPESENLQEFWDNLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 DASFFGVHPKQAHTMDPQLRLLLEVTYEAIVDGGINPDSLRGTHTGVWVGVSGSETSEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DASFFGVHPKQAHTMDPQLRLLLEVTYEAIVDGGINPDSLRGTHTGVWVGVSGSETSEAL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SRDPETLVGYSMVGCQRAMMANRLSFFFDFRGPSIALDTACSSSLMALQNAYQAIHSGQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SRDPETLVGYSMVGCQRAMMANRLSFFFDFRGPSIALDTACSSSLMALQNAYQAIHSGQC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 PAAIVGGINVLLKPNTSVQFLRLGMLSPEGTCKAFDTAGNGYCRSEGVVAVLLTKKSLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PAAIVGGINVLLKPNTSVQFLRLGMLSPEGTCKAFDTAGNGYCRSEGVVAVLLTKKSLAR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 RVYATILNAGTNTDGFKEQGVTFPSGDIQEQLIRSLYQSAGVAPESFEYIEAHGTGTKVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RVYATILNAGTNTDGFKEQGVTFPSGDIQEQLIRSLYQSAGVAPESFEYIEAHGTGTKVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DPQELNGITRALCATRQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DPQELNGITRALCATRQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 SPNPEIPALLDGRLQVVDQPLPVRGGNVGINSFGFGGSNVHIILRPNTQPPPAPAPHATL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SPNPEIPALLDGRLQVVDQPLPVRGGNVGINSFGFGGSNVHIILRPNTQPPPAPAPHATL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 PRLLRASGRTPEAVQKLLEQGLRHSQDLAFLSMLNDIAAVPATAMPFRGYAVLGGERGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PRLLRASGRTPEAVQKLLEQGLRHSQDLAFLSMLNDIAAVPATAMPFRGYAVLGGERGGP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 EVQQVPAGERPLWFICSGMGTQWRGMGLSLMRLDRFRDSILRSDEAVKPFGLKVSQLLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EVQQVPAGERPLWFICSGMGTQWRGMGLSLMRLDRFRDSILRSDEAVKPFGLKVSQLLLS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 TDESTFDDIVHSFVSLTAIQIGLIDLLSCMGLRPDGIVGHSLGEVACGYADGCLSQEEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TDESTFDDIVHSFVSLTAIQIGLIDLLSCMGLRPDGIVGHSLGEVACGYADGCLSQEEAV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 LAAYWRGQCIKEAHLPPGAMAAVGLSWEECKQRCPPGVVPACHNSKDTVTISGPQAPVFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LAAYWRGQCIKEAHLPPGAMAAVGLSWEECKQRCPPGVVPACHNSKDTVTISGPQAPVFE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 FVEQLRKEGVFAKEVRTGGMAFHSYFMEAIAPPLLQELKKVIREPKPRSARWLSTSIPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FVEQLRKEGVFAKEVRTGGMAFHSYFMEAIAPPLLQELKKVIREPKPRSARWLSTSIPEA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 QWHSSLARTSSAEYNVNNLVSPVLFQEALWHVPEHAVVLEIAPHALLQAVLKRGLKPSCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QWHSSLARTSSAEYNVNNLVSPVLFQEALWHVPEHAVVLEIAPHALLQAVLKRGLKPSCT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 IIPLMKKDHRDNLEFFLAGIGRLHLSGIDANPNALFPPVEFPAPRGTPLISPLIKWDHSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IIPLMKKDHRDNLEFFLAGIGRLHLSGIDANPNALFPPVEFPAPRGTPLISPLIKWDHSL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 AWDVPAAEDFPNGSGSPSAAIYNIDTSSESPDHYLVDHTLDGRVLFPATGYLSIVWKTLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AWDVPAAEDFPNGSGSPSAAIYNIDTSSESPDHYLVDHTLDGRVLFPATGYLSIVWKTLA
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 RALGLGVEQLPVVFEDVVLHQATILPKTGTVSLEVRLLEASRAFEVSENGNLVVSGKVYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RALGLGVEQLPVVFEDVVLHQATILPKTGTVSLEVRLLEASRAFEVSENGNLVVSGKVYQ
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 WDDPDPRLFDHPESPTPNPTEPLFLAQAEVYKELRLRGYDYGPHFQGILEASLEGDSGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 WDDPDPRLFDHPESPTPNPTEPLFLAQAEVYKELRLRGYDYGPHFQGILEASLEGDSGRL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 LWKDNWVSFMDTMLQMSILGSAKHGLYLPTRVTAIHIDPATHRQKLYTLQDKAQVADVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LWKDNWVSFMDTMLQMSILGSAKHGLYLPTRVTAIHIDPATHRQKLYTLQDKAQVADVVV
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 SRWLRVTVAGGVHISGLHTESAPRRQQEQQVPILEKFCFTPHTEEGCLSERAALQEELQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SRWLRVTVAGGVHISGLHTESAPRRQQEQQVPILEKFCFTPHTEEGCLSERAALQEELQL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 CKGLVQALQTKVTQQGLKMVVPGLDGAQIPRDPSQQELPRLLSAACRLQLNGNLQLELAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CKGLVQALQTKVTQQGLKMVVPGLDGAQIPRDPSQQELPRLLSAACRLQLNGNLQLELAQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 VLAQERPKLPEDPLLSGLLDSPALKACLDTAVENMPSLKMKVVEVLAGHGHLYSRIPGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VLAQERPKLPEDPLLSGLLDSPALKACLDTAVENMPSLKMKVVEVLAGHGHLYSRIPGLL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 SPHPLLQLSYTATDRHPQALEAAQAELQQHDVAQGQWDPADPAPSALGSADLLVCNCAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SPHPLLQLSYTATDRHPQALEAAQAELQQHDVAQGQWDPADPAPSALGSADLLVCNCAVA
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 ALGDPASALSNMVAALREGGFLLLHTLLRGHPLGDIVAFLTSTEPQYGQGILSQDAWESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ALGDPASALSNMVAALREGGFLLLHTLLRGHPLGDIVAFLTSTEPQYGQGILSQDAWESL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 FSRVSLRLVGLKKSFYGSTLFLCRRPTPQDSPIFLPVDDTSFRWVESLKGILADEDSSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FSRVSLRLVGLKKSFYGSTLFLCRRPTPQDSPIFLPVDDTSFRWVESLKGILADEDSSRP
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB0 VWLKAINCATSGVVGLVNCLRREPGGNRLRCVLLSNLSSTSHVPEVDPGSAELQKVLQGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VWLKAINCATSGVVGLVNCLRREPGGNRLRCVLLSNLSSTSHVPEVDPGSAELQKVLQGD
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB0 LVMNVYRDGAWGAFRHFLLEEDKPEEPTAHAFVSTLTRGDLSSIRWVCSSLRHAQPTCPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LVMNVYRDGAWGAFRHFLLEEDKPEEPTAHAFVSTLTRGDLSSIRWVCSSLRHAQPTCPG
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB0 AQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFSGRDASGKRVMGLVPAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFSGRDASGKRVMGLVPAK
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB0 GLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGV
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KB0 GQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSFEQHVLWHTGGKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSFEQHVLWHTGGKG
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KB0 VDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGVLLDAFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGVLLDAFF
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KB0 NESSADWREVWALVQAGIRDGVVRPLKCTVFHGAQVEDAFRYMAQGKHIGKVVVQVLAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NESSADWREVWALVQAGIRDGVVRPLKCTVFHGAQVEDAFRYMAQGKHIGKVVVQVLAEE
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KB0 PEAVLKGAKPKLMSAISKTFCPAHKSYIIAGGLGGFGLELAQWLIQRGVQKLVLTSRSGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PEAVLKGAKPKLMSAISKTFCPAHKSYIIAGGLGGFGLELAQWLIQRGVQKLVLTSRSGI
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KB0 RTGYQAKQVRRWRRQGVQVQVSTSNISSLEGARGLIAEAAQLGPVGGVFNLAVVLRDGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RTGYQAKQVRRWRRQGVQVQVSTSNISSLEGARGLIAEAAQLGPVGGVFNLAVVLRDGLL
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KB0 ENQTPEFFQDVCKPKYSGTLNLDRVTREACPELDYFVVFSSVSCGRGNAGQSNYGFANSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ENQTPEFFQDVCKPKYSGTLNLDRVTREACPELDYFVVFSSVSCGRGNAGQSNYGFANSA
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KB0 MERICEKRRHEGLPGLAVQWGAIGDVGILVETMSTNDTIVSGTLPQRMASCLEVLDLFLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MERICEKRRHEGLPGLAVQWGAIGDVGILVETMSTNDTIVSGTLPQRMASCLEVLDLFLN
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KB0 QPHMVLSSFVLAEKAAAYRDRDSQRDLVEAVAHILGIRDLAAVNLDSSLADLGLDSLMSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QPHMVLSSFVLAEKAAAYRDRDSQRDLVEAVAHILGIRDLAAVNLDSSLADLGLDSLMSV
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KB0 EVRQTLERELNLVLSVREVRQLTLRKLQELSSKADEASELACPTPKEDGLAQQQTQLNLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EVRQTLERELNLVLSVREVRQLTLRKLQELSSKADEASELACPTPKEDGLAQQQTQLNLR
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KB0 SLLVNPEGPTLMRLNSVQSSERPLFLVHPIEGSTTVFHSLASRLSIPTYGLQCTRAAPLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SLLVNPEGPTLMRLNSVQSSERPLFLVHPIEGSTTVFHSLASRLSIPTYGLQCTRAAPLD
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KB0 SIHSLAAYYIDCIRQVQPEGPYRVAGYSYGACVAFEMCSQLQAQQSPAPTHNSLFLFDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SIHSLAAYYIDCIRQVQPEGPYRVAGYSYGACVAFEMCSQLQAQQSPAPTHNSLFLFDGS
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KB0 PTYVLAYTQSYRAKLTPGCEAEAETEAICFFVQQFTDMEHNRVLEALLPLKGLEERVAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PTYVLAYTQSYRAKLTPGCEAEAETEAICFFVQQFTDMEHNRVLEALLPLKGLEERVAAA
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KB0 VDLIIKSHQGLDRQELSFAARSFYYKLRAAEQYTPKAKYHGNVMLLRAKTGGAYGEDLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VDLIIKSHQGLDRQELSFAARSFYYKLRAAEQYTPKAKYHGNVMLLRAKTGGAYGEDLGA
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510
pF1KB0 DYNLSQVCDGKVSVHVIEGDHRTLLEGSGLESIISIIHSSLAEPRVSVREG
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DYNLSQVCDGKVSVHVIEGDHRTLLEGSGLESIISIIHSSLAEPRVSVREG
2470 2480 2490 2500 2510
>>XP_016862202 (OMIM: 610324) PREDICTED: 3-oxoacyl-[acyl (459 aa)
initn: 346 init1: 121 opt: 403 Z-score: 418.5 bits: 89.2 E(85289): 1.4e-16
Smith-Waterman score: 404; 26.3% identity (56.4% similar) in 422 aa overlap (4-399:44-451)
10 20
pF1KB0 MEEVVIAGMSGKLPESENLQEFWDNLIGG----
:::.:.. : . . . :: ::::
XP_016 TRLLCSRLCQQLRSKRKFFGTVPISRLHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGI
20 30 40 50 60 70
30 40 50 60 70 80
pF1KB0 VDMVTDDDRRWKAGLYG-LPRRSGKLKDLSRFDASFFGVHPKQAHTMDPQLRLLLEVTYE
:..: .. . .. . .:: : : ..:. . : : .. ..:. . . ..
XP_016 VSLVGEEYKSIPCSVAAYVPRGS----DEGQFNEQNF-VSKSDIKSMSSPTIMAIGAAEL
80 90 100 110 120
90 100 110 120 130
pF1KB0 AIVDGGINPDSLRG-THTGVWVGVSGSETSEALSRDPETLVGYSMVGCQRA---------
:. :.: .:.: . ::: .:. : :..: :: .... : ...
XP_016 AMKDSGWHPQSEADQVATGVAIGM-GMIPLEVVS---ETALNFQTKGYNKVSPFFVPKIL
130 140 150 160 170 180
140 150 160 170 180 190
pF1KB0 --MMANRLSFFFDFRGPSIALDTACSSSLMALQNAYQAIHSGQCPAAIVGGINVLLKPNT
: :...:. . ..::. :..:::... :. .... : :. . ..:: . ..: .
XP_016 VNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLS
190 200 210 220 230 240
200 210 220 230 240
pF1KB0 SVQFLRLGMLS----PEGTCKAFDTAGNGYCRSEGVVAVLLTK--KSLARR--VYATILN
. : : :: :. .:. : .:. .::.....: . ... :: .:: .:.
XP_016 LAGFSRARALSTNSDPKLACRPFHPKRDGFVMGEGAAVLVLEEYEHAVQRRARIYAEVLG
250 260 270 280 290 300
250 260 270 280 290 300
pF1KB0 AGTNTDGFKEQGVTFPSGDIQEQLIRSLYQSAGVAPESFEYIEAHGTGTKVGDPQELNGI
: . :. . . : :. . . . ..::: :: . ::.::.:.: .:: : :
XP_016 YGLSGDAGHITAPD-PEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAE-NKA
310 320 330 340 350 360
310 320 330 340 350 360
pF1KB0 TRALCATRQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFHSPNPEIPA
. : . : ..:::. :: :.: . : . :. . :.:.. .::.
XP_016 IKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEFDL
370 380 390 400 410 420
370 380 390 400 410 420
pF1KB0 LLDGRLQVVDQPLPVRGGNVGI-NSFGFGGSNVHIILRPNTQPPPAPAPHATLPRLLRAS
. . . : .. .:. :::::::.:
XP_016 ---NYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIAGL
430 440 450
430 440 450 460 470 480
pF1KB0 GRTPEAVQKLLEQGLRHSQDLAFLSMLNDIAAVPATAMPFRGYAVLGGERGGPEVQQVPA
>>NP_060367 (OMIM: 610324) 3-oxoacyl-[acyl-carrier-prote (459 aa)
initn: 346 init1: 121 opt: 403 Z-score: 418.5 bits: 89.2 E(85289): 1.4e-16
Smith-Waterman score: 404; 26.3% identity (56.4% similar) in 422 aa overlap (4-399:44-451)
10 20
pF1KB0 MEEVVIAGMSGKLPESENLQEFWDNLIGG----
:::.:.. : . . . :: ::::
NP_060 TRLLCSRLCQQLRSKRKFFGTVPISRLHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGI
20 30 40 50 60 70
30 40 50 60 70 80
pF1KB0 VDMVTDDDRRWKAGLYG-LPRRSGKLKDLSRFDASFFGVHPKQAHTMDPQLRLLLEVTYE
:..: .. . .. . .:: : : ..:. . : : .. ..:. . . ..
NP_060 VSLVGEEYKSIPCSVAAYVPRGS----DEGQFNEQNF-VSKSDIKSMSSPTIMAIGAAEL
80 90 100 110 120
90 100 110 120 130
pF1KB0 AIVDGGINPDSLRG-THTGVWVGVSGSETSEALSRDPETLVGYSMVGCQRA---------
:. :.: .:.: . ::: .:. : :..: :: .... : ...
NP_060 AMKDSGWHPQSEADQVATGVAIGM-GMIPLEVVS---ETALNFQTKGYNKVSPFFVPKIL
130 140 150 160 170 180
140 150 160 170 180 190
pF1KB0 --MMANRLSFFFDFRGPSIALDTACSSSLMALQNAYQAIHSGQCPAAIVGGINVLLKPNT
: :...:. . ..::. :..:::... :. .... : :. . ..:: . ..: .
NP_060 VNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLS
190 200 210 220 230 240
200 210 220 230 240
pF1KB0 SVQFLRLGMLS----PEGTCKAFDTAGNGYCRSEGVVAVLLTK--KSLARR--VYATILN
. : : :: :. .:. : .:. .::.....: . ... :: .:: .:.
NP_060 LAGFSRARALSTNSDPKLACRPFHPKRDGFVMGEGAAVLVLEEYEHAVQRRARIYAEVLG
250 260 270 280 290 300
250 260 270 280 290 300
pF1KB0 AGTNTDGFKEQGVTFPSGDIQEQLIRSLYQSAGVAPESFEYIEAHGTGTKVGDPQELNGI
: . :. . . : :. . . . ..::: :: . ::.::.:.: .:: : :
NP_060 YGLSGDAGHITAPD-PEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAE-NKA
310 320 330 340 350 360
310 320 330 340 350 360
pF1KB0 TRALCATRQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFHSPNPEIPA
. : . : ..:::. :: :.: . : . :. . :.:.. .::.
NP_060 IKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEFDL
370 380 390 400 410 420
370 380 390 400 410 420
pF1KB0 LLDGRLQVVDQPLPVRGGNVGI-NSFGFGGSNVHIILRPNTQPPPAPAPHATLPRLLRAS
. . . : .. .:. :::::::.:
NP_060 ---NYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIAGL
430 440 450
430 440 450 460 470 480
pF1KB0 GRTPEAVQKLLEQGLRHSQDLAFLSMLNDIAAVPATAMPFRGYAVLGGERGGPEVQQVPA
>>XP_006713279 (OMIM: 610324) PREDICTED: 3-oxoacyl-[acyl (459 aa)
initn: 346 init1: 121 opt: 403 Z-score: 418.5 bits: 89.2 E(85289): 1.4e-16
Smith-Waterman score: 404; 26.3% identity (56.4% similar) in 422 aa overlap (4-399:44-451)
10 20
pF1KB0 MEEVVIAGMSGKLPESENLQEFWDNLIGG----
:::.:.. : . . . :: ::::
XP_006 TRLLCSRLCQQLRSKRKFFGTVPISRLHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGI
20 30 40 50 60 70
30 40 50 60 70 80
pF1KB0 VDMVTDDDRRWKAGLYG-LPRRSGKLKDLSRFDASFFGVHPKQAHTMDPQLRLLLEVTYE
:..: .. . .. . .:: : : ..:. . : : .. ..:. . . ..
XP_006 VSLVGEEYKSIPCSVAAYVPRGS----DEGQFNEQNF-VSKSDIKSMSSPTIMAIGAAEL
80 90 100 110 120
90 100 110 120 130
pF1KB0 AIVDGGINPDSLRG-THTGVWVGVSGSETSEALSRDPETLVGYSMVGCQRA---------
:. :.: .:.: . ::: .:. : :..: :: .... : ...
XP_006 AMKDSGWHPQSEADQVATGVAIGM-GMIPLEVVS---ETALNFQTKGYNKVSPFFVPKIL
130 140 150 160 170 180
140 150 160 170 180 190
pF1KB0 --MMANRLSFFFDFRGPSIALDTACSSSLMALQNAYQAIHSGQCPAAIVGGINVLLKPNT
: :...:. . ..::. :..:::... :. .... : :. . ..:: . ..: .
XP_006 VNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLS
190 200 210 220 230 240
200 210 220 230 240
pF1KB0 SVQFLRLGMLS----PEGTCKAFDTAGNGYCRSEGVVAVLLTK--KSLARR--VYATILN
. : : :: :. .:. : .:. .::.....: . ... :: .:: .:.
XP_006 LAGFSRARALSTNSDPKLACRPFHPKRDGFVMGEGAAVLVLEEYEHAVQRRARIYAEVLG
250 260 270 280 290 300
250 260 270 280 290 300
pF1KB0 AGTNTDGFKEQGVTFPSGDIQEQLIRSLYQSAGVAPESFEYIEAHGTGTKVGDPQELNGI
: . :. . . : :. . . . ..::: :: . ::.::.:.: .:: : :
XP_006 YGLSGDAGHITAPD-PEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAE-NKA
310 320 330 340 350 360
310 320 330 340 350 360
pF1KB0 TRALCATRQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFHSPNPEIPA
. : . : ..:::. :: :.: . : . :. . :.:.. .::.
XP_006 IKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEFDL
370 380 390 400 410 420
370 380 390 400 410 420
pF1KB0 LLDGRLQVVDQPLPVRGGNVGI-NSFGFGGSNVHIILRPNTQPPPAPAPHATLPRLLRAS
. . . : .. .:. :::::::.:
XP_006 ---NYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIAGL
430 440 450
430 440 450 460 470 480
pF1KB0 GRTPEAVQKLLEQGLRHSQDLAFLSMLNDIAAVPATAMPFRGYAVLGGERGGPEVQQVPA
>>NP_004872 (OMIM: 605171) quinone oxidoreductase PIG3 i (332 aa)
initn: 242 init1: 143 opt: 347 Z-score: 362.2 bits: 78.3 E(85289): 2e-13
Smith-Waterman score: 356; 28.6% identity (56.3% similar) in 325 aa overlap (1554-1856:21-330)
1530 1540 1550 1560 1570 1580
pF1KB0 PEEPTAHAFVSTLTRGDLSSIRWVCSSLRHAQPTCPGAQ--LCTVYYASLNFRDIMLATG
:.:. :: : : ..:: :.: :
NP_004 MLAVHFDKPGGPENLYVKEVAKPS-PGEGEVLLKVAASALNRADLMQRQG
10 20 30 40
1590 1600 1610 1620 1630
pF1KB0 KLSPDAIPGKWTSQDSLLGMEFSGRDAS-----------GKRVMGLVPAKGLATSVLLSP
. .: :: ...::.: ::. : : .:.:.:. : : : .
NP_004 QYDPP--PG----ASNILGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPE
50 60 70 80 90 100
1640 1650 1660 1670 1680 1690
pF1KB0 DFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALS
.: .: . :: .::..: .. ::. : . : :. :. .:::.: .::: ::: ..
NP_004 GLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRM
110 120 130 140 150 160
1700 1710 1720 1730 1740 1750
pF1KB0 LGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSFEQHVLWHTGGKGVDLVLNSLAE
: ..:.:: .: :: .: ... : . .: . .: : : ::.:.:. ..
NP_004 AGAIPLVTAGSQKK---LQMA-EKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGG
170 180 190 200 210
1760 1770 1780 1790 1800
pF1KB0 EKLQASVRCLATHGRFLEIGKFDLSQ-NHPLGMAIFLKNVTFHGVLLDAFFNESSADWRE
. .: ::: ::.. : . .. : :: ...: .: :. ... . ...
NP_004 SYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFK----RGSLITSLLRSRDNKYKQ
220 230 240 250 260 270
1810 1820 1830 1840 1850 1860
pF1KB0 --VWALVQAGI----RDGVVR--PLKCTVFHGAQVEDAFRYMAQGKHIGKVVVQVLAEEP
: :... . .: : :. .. .....: .:: .:.:::.:...
NP_004 MLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ
280 290 300 310 320 330
1870 1880 1890 1900 1910 1920
pF1KB0 EAVLKGAKPKLMSAISKTFCPAHKSYIIAGGLGGFGLELAQWLIQRGVQKLVLTSRSGIR
>>NP_671713 (OMIM: 605171) quinone oxidoreductase PIG3 i (332 aa)
initn: 242 init1: 143 opt: 347 Z-score: 362.2 bits: 78.3 E(85289): 2e-13
Smith-Waterman score: 356; 28.6% identity (56.3% similar) in 325 aa overlap (1554-1856:21-330)
1530 1540 1550 1560 1570 1580
pF1KB0 PEEPTAHAFVSTLTRGDLSSIRWVCSSLRHAQPTCPGAQ--LCTVYYASLNFRDIMLATG
:.:. :: : : ..:: :.: :
NP_671 MLAVHFDKPGGPENLYVKEVAKPS-PGEGEVLLKVAASALNRADLMQRQG
10 20 30 40
1590 1600 1610 1620 1630
pF1KB0 KLSPDAIPGKWTSQDSLLGMEFSGRDAS-----------GKRVMGLVPAKGLATSVLLSP
. .: :: ...::.: ::. : : .:.:.:. : : : .
NP_671 QYDPP--PG----ASNILGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPE
50 60 70 80 90 100
1640 1650 1660 1670 1680 1690
pF1KB0 DFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALS
.: .: . :: .::..: .. ::. : . : :. :. .:::.: .::: ::: ..
NP_671 GLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRM
110 120 130 140 150 160
1700 1710 1720 1730 1740 1750
pF1KB0 LGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSFEQHVLWHTGGKGVDLVLNSLAE
: ..:.:: .: :: .: ... : . .: . .: : : ::.:.:. ..
NP_671 AGAIPLVTAGSQKK---LQMA-EKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGG
170 180 190 200 210
1760 1770 1780 1790 1800
pF1KB0 EKLQASVRCLATHGRFLEIGKFDLSQ-NHPLGMAIFLKNVTFHGVLLDAFFNESSADWRE
. .: ::: ::.. : . .. : :: ...: .: :. ... . ...
NP_671 SYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFK----RGSLITSLLRSRDNKYKQ
220 230 240 250 260 270
1810 1820 1830 1840 1850 1860
pF1KB0 --VWALVQAGI----RDGVVR--PLKCTVFHGAQVEDAFRYMAQGKHIGKVVVQVLAEEP
: :... . .: : :. .. .....: .:: .:.:::.:...
NP_671 MLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ
280 290 300 310 320 330
1870 1880 1890 1900 1910 1920
pF1KB0 EAVLKGAKPKLMSAISKTFCPAHKSYIIAGGLGGFGLELAQWLIQRGVQKLVLTSRSGIR
>>XP_011539049 (OMIM: 123691) PREDICTED: quinone oxidore (329 aa)
initn: 143 init1: 143 opt: 250 Z-score: 261.0 bits: 59.5 E(85289): 8.4e-08
Smith-Waterman score: 301; 25.8% identity (58.9% similar) in 302 aa overlap (1563-1854:39-327)
1540 1550 1560 1570 1580 1590
pF1KB0 VSTLTRGDLSSIRWVCSSLRHAQPTCPGAQLCTVYYASLNFRDIMLATGKLS-PDAIPGK
: :. ..: . .. .: : .:
XP_011 RAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLP--
10 20 30 40 50 60
1600 1610 1620 1630 1640
pF1KB0 WTSQDSLLG-MEFSGRDAS----GKRVM-GLVPAKGLATSVLLSPDFLWDVPSNWTLEEA
.: ... : .: : .:: : ::. . . . : : .: . .. .: . ....
XP_011 YTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQG
70 80 90 100 110 120
1650 1660 1670 1680 1690 1700
pF1KB0 ASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAE-K
:.. . : ::: ::. . :. ::..:.:..::::: :: :: . : ... :.:. : .
XP_011 AAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQ
130 140 150 160 170 180
1710 1720 1730 1740 1750 1760
pF1KB0 RAYLQARFPQLDSTSFANSRDTSFEQHVLWHTGGKGVDLVLNSLAEEKLQASVRCLATHG
. :: . : :.... ... ..: ::.:.... ::. .:. .. :. :
XP_011 KIVLQN-----GAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGG
190 200 210 220 230 240
1770 1780 1790 1800 1810 1820
pF1KB0 RFLEIGKFDLSQNHPLG-MAIFLKNVTFHGVLLDAFFNESSADWREVWALVQAGIRDGVV
: . .:. . .: :: :. .. :: : :. .. .... : .:::.. : .
XP_011 RVIVVGSRGTIEINPRDTMA---KESSIIGVTL---FSSTKEEFQQYAAALQAGMEIGWL
250 260 270 280 290
1830 1840 1850 1860 1870 1880
pF1KB0 RPLKCTVFHGAQVEDAFRYMAQGKHI-GKVVVQVLAEEPEAVLKGAKPKLMSAISKTFCP
.:. . . .: .: . . .:. ::...
XP_011 KPVIGSQYPLEKVAEAHENIIHGSGATGKMILLL
300 310 320
1890 1900 1910 1920 1930 1940
pF1KB0 AHKSYIIAGGLGGFGLELAQWLIQRGVQKLVLTSRSGIRTGYQAKQVRRWRRQGVQVQVS
>>NP_001123514 (OMIM: 123691) quinone oxidoreductase iso (329 aa)
initn: 143 init1: 143 opt: 250 Z-score: 261.0 bits: 59.5 E(85289): 8.4e-08
Smith-Waterman score: 301; 25.8% identity (58.9% similar) in 302 aa overlap (1563-1854:39-327)
1540 1550 1560 1570 1580 1590
pF1KB0 VSTLTRGDLSSIRWVCSSLRHAQPTCPGAQLCTVYYASLNFRDIMLATGKLS-PDAIPGK
: :. ..: . .. .: : .:
NP_001 RAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLP--
10 20 30 40 50 60
1600 1610 1620 1630 1640
pF1KB0 WTSQDSLLG-MEFSGRDAS----GKRVM-GLVPAKGLATSVLLSPDFLWDVPSNWTLEEA
.: ... : .: : .:: : ::. . . . : : .: . .. .: . ....
NP_001 YTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQG
70 80 90 100 110 120
1650 1660 1670 1680 1690 1700
pF1KB0 ASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAE-K
:.. . : ::: ::. . :. ::..:.:..::::: :: :: . : ... :.:. : .
NP_001 AAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQ
130 140 150 160 170 180
1710 1720 1730 1740 1750 1760
pF1KB0 RAYLQARFPQLDSTSFANSRDTSFEQHVLWHTGGKGVDLVLNSLAEEKLQASVRCLATHG
. :: . : :.... ... ..: ::.:.... ::. .:. .. :. :
NP_001 KIVLQN-----GAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGG
190 200 210 220 230 240
1770 1780 1790 1800 1810 1820
pF1KB0 RFLEIGKFDLSQNHPLG-MAIFLKNVTFHGVLLDAFFNESSADWREVWALVQAGIRDGVV
: . .:. . .: :: :. .. :: : :. .. .... : .:::.. : .
NP_001 RVIVVGSRGTIEINPRDTMA---KESSIIGVTL---FSSTKEEFQQYAAALQAGMEIGWL
250 260 270 280 290
1830 1840 1850 1860 1870 1880
pF1KB0 RPLKCTVFHGAQVEDAFRYMAQGKHI-GKVVVQVLAEEPEAVLKGAKPKLMSAISKTFCP
.:. . . .: .: . . .:. ::...
NP_001 KPVIGSQYPLEKVAEAHENIIHGSGATGKMILLL
300 310 320
1890 1900 1910 1920 1930 1940
pF1KB0 AHKSYIIAGGLGGFGLELAQWLIQRGVQKLVLTSRSGIRTGYQAKQVRRWRRQGVQVQVS
>>NP_001880 (OMIM: 123691) quinone oxidoreductase isofor (329 aa)
initn: 143 init1: 143 opt: 250 Z-score: 261.0 bits: 59.5 E(85289): 8.4e-08
Smith-Waterman score: 301; 25.8% identity (58.9% similar) in 302 aa overlap (1563-1854:39-327)
1540 1550 1560 1570 1580 1590
pF1KB0 VSTLTRGDLSSIRWVCSSLRHAQPTCPGAQLCTVYYASLNFRDIMLATGKLS-PDAIPGK
: :. ..: . .. .: : .:
NP_001 RAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLP--
10 20 30 40 50 60
1600 1610 1620 1630 1640
pF1KB0 WTSQDSLLG-MEFSGRDAS----GKRVM-GLVPAKGLATSVLLSPDFLWDVPSNWTLEEA
.: ... : .: : .:: : ::. . . . : : .: . .. .: . ....
NP_001 YTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQG
70 80 90 100 110 120
1650 1660 1670 1680 1690 1700
pF1KB0 ASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAE-K
:.. . : ::: ::. . :. ::..:.:..::::: :: :: . : ... :.:. : .
NP_001 AAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQ
130 140 150 160 170 180
1710 1720 1730 1740 1750 1760
pF1KB0 RAYLQARFPQLDSTSFANSRDTSFEQHVLWHTGGKGVDLVLNSLAEEKLQASVRCLATHG
. :: . : :.... ... ..: ::.:.... ::. .:. .. :. :
NP_001 KIVLQN-----GAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGG
190 200 210 220 230 240
1770 1780 1790 1800 1810 1820
pF1KB0 RFLEIGKFDLSQNHPLG-MAIFLKNVTFHGVLLDAFFNESSADWREVWALVQAGIRDGVV
: . .:. . .: :: :. .. :: : :. .. .... : .:::.. : .
NP_001 RVIVVGSRGTIEINPRDTMA---KESSIIGVTL---FSSTKEEFQQYAAALQAGMEIGWL
250 260 270 280 290
1830 1840 1850 1860 1870 1880
pF1KB0 RPLKCTVFHGAQVEDAFRYMAQGKHI-GKVVVQVLAEEPEAVLKGAKPKLMSAISKTFCP
.:. . . .: .: . . .:. ::...
NP_001 KPVIGSQYPLEKVAEAHENIIHGSGATGKMILLL
300 310 320
1890 1900 1910 1920 1930 1940
pF1KB0 AHKSYIIAGGLGGFGLELAQWLIQRGVQKLVLTSRSGIRTGYQAKQVRRWRRQGVQVQVS
2511 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 22:29:32 2016 done: Wed Nov 2 22:29:35 2016
Total Scan time: 21.520 Total Display time: 0.740
Function used was FASTA [36.3.4 Apr, 2011]