FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0006, 2265 aa 1>>>pF1KB0006 2265 - 2265 aa - 2265 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6990+/-0.00118; mu= 13.9605+/- 0.071 mean_var=144.6697+/-28.898, 0's: 0 Z-trim(107.0): 112 B-trim: 211 in 1/50 Lambda= 0.106631 statistics sampled from 9203 (9316) to 9203 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.621), E-opt: 0.2 (0.286), width: 16 Scan time: 6.150 The best scores are: opt bits E(32554) CCDS77523.1 FN1 gene_id:2335|Hs108|chr2 (2265) 15577 2409.9 0 CCDS42813.1 FN1 gene_id:2335|Hs108|chr2 (2296) 13597 2105.4 0 CCDS2400.1 FN1 gene_id:2335|Hs108|chr2 (2176) 12991 2012.1 0 CCDS77522.1 FN1 gene_id:2335|Hs108|chr2 (2240) 12968 2008.6 0 CCDS77525.1 FN1 gene_id:2335|Hs108|chr2 (2267) 11845 1835.8 0 CCDS2399.1 FN1 gene_id:2335|Hs108|chr2 (2355) 11675 1809.7 0 CCDS46510.1 FN1 gene_id:2335|Hs108|chr2 (2330) 11638 1804.0 0 CCDS77526.1 FN1 gene_id:2335|Hs108|chr2 (2446) 9889 1534.9 0 CCDS42814.1 FN1 gene_id:2335|Hs108|chr2 (2477) 9889 1534.9 0 CCDS46512.1 FN1 gene_id:2335|Hs108|chr2 ( 657) 4805 752.5 1.4e-216 CCDS2773.1 COL7A1 gene_id:1294|Hs108|chr3 (2944) 790 135.2 4.3e-30 CCDS43481.1 COL12A1 gene_id:1303|Hs108|chr6 (1899) 747 128.5 2.9e-28 CCDS6811.1 TNC gene_id:3371|Hs108|chr9 (2201) 583 103.3 1.3e-20 CCDS30943.1 TNN gene_id:63923|Hs108|chr1 (1299) 563 100.1 7.1e-20 CCDS46628.1 COL20A1 gene_id:57642|Hs108|chr20 (1284) 561 99.8 8.7e-20 CCDS76869.1 MMP2 gene_id:4313|Hs108|chr16 ( 584) 509 91.6 1.2e-17 CCDS45487.1 MMP2 gene_id:4313|Hs108|chr16 ( 610) 509 91.6 1.2e-17 CCDS10752.1 MMP2 gene_id:4313|Hs108|chr16 ( 660) 509 91.6 1.3e-17 CCDS1318.1 TNR gene_id:7143|Hs108|chr1 (1358) 433 80.1 7.7e-14 CCDS43482.1 COL12A1 gene_id:1303|Hs108|chr6 (3063) 409 76.6 1.9e-12 CCDS34938.1 COL14A1 gene_id:7373|Hs108|chr8 (1796) 377 71.6 3.8e-11 >>CCDS77523.1 FN1 gene_id:2335|Hs108|chr2 (2265 aa) initn: 15577 init1: 15577 opt: 15577 Z-score: 12949.5 bits: 2409.9 E(32554): 0 Smith-Waterman score: 15577; 99.9% identity (100.0% similar) in 2265 aa overlap (1-2265:1-2265) 10 20 30 40 50 60 pF1KB0 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: CCDS77 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDTTVDQVDDTSIVVRWSRPQAPITG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB0 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB0 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB0 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB0 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB0 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB0 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KB0 LDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIR 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KB0 HRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 HRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTG 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KB0 LTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEW ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LTRGATYNVIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEW 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KB0 ERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 ERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGN 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KB0 GKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 GKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPS 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 pF1KB0 PEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE ::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2230 2240 2250 2260 >>CCDS42813.1 FN1 gene_id:2335|Hs108|chr2 (2296 aa) initn: 14228 init1: 13592 opt: 13597 Z-score: 11303.2 bits: 2105.4 E(32554): 0 Smith-Waterman score: 15505; 98.6% identity (98.6% similar) in 2296 aa overlap (1-2265:1-2296) 10 20 30 40 50 60 pF1KB0 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: CCDS42 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDTTVDQVDDTSIVVRWSRPQAPITG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB0 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB0 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB0 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB0 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB0 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB0 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KB0 LDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIR 1930 1940 1950 1960 1970 1980 1990 2000 pF1KB0 HRPRPYPPNVG-------------------------------QEALSQTTISWAPFQDTS ::::::::::: :::::::::::::::::: CCDS42 HRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTS 1990 2000 2010 2020 2030 2040 2010 2020 2030 2040 2050 2060 pF1KB0 EYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTV :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: CCDS42 EYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNVIVEALKDQQRHKVREEVVTV 2050 2060 2070 2080 2090 2100 2070 2080 2090 2100 2110 2120 pF1KB0 GNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 GNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRW 2110 2120 2130 2140 2150 2160 2130 2140 2150 2160 2170 2180 pF1KB0 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQK 2170 2180 2190 2200 2210 2220 2190 2200 2210 2220 2230 2240 pF1KB0 EYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 EYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIE 2230 2240 2250 2260 2270 2280 2250 2260 pF1KB0 CFMPLDVQADREDSRE :::::::::::::::: CCDS42 CFMPLDVQADREDSRE 2290 >>CCDS2400.1 FN1 gene_id:2335|Hs108|chr2 (2176 aa) initn: 12942 init1: 12942 opt: 12991 Z-score: 10799.7 bits: 2012.1 E(32554): 0 Smith-Waterman score: 14754; 96.0% identity (96.0% similar) in 2265 aa overlap (1-2265:1-2176) 10 20 30 40 50 60 pF1KB0 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: CCDS24 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDTTVDQVDDTSIVVRWSRPQAPITG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB0 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB0 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB0 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB0 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB0 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB0 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI ::::::::::::::::::::::::::::::::::::::::: CCDS24 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT------------------- 1870 1880 1890 1900 1930 1940 1950 1960 1970 1980 pF1KB0 LDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIR CCDS24 ------------------------------------------------------------ 1990 2000 2010 2020 2030 2040 pF1KB0 HRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTG :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 ----------GQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTG 1910 1920 1930 1940 1950 2050 2060 2070 2080 2090 2100 pF1KB0 LTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEW ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 LTRGATYNVIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEW 1960 1970 1980 1990 2000 2010 2110 2120 2130 2140 2150 2160 pF1KB0 ERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 ERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGN 2020 2030 2040 2050 2060 2070 2170 2180 2190 2200 2210 2220 pF1KB0 GKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 GKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPS 2080 2090 2100 2110 2120 2130 2230 2240 2250 2260 pF1KB0 PEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE ::::::::::::::::::::::::::::::::::::::::::::: CCDS24 PEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2140 2150 2160 2170 >>CCDS77522.1 FN1 gene_id:2335|Hs108|chr2 (2240 aa) initn: 13588 init1: 12952 opt: 12968 Z-score: 10780.4 bits: 2008.6 E(32554): 0 Smith-Waterman score: 15342; 98.8% identity (98.9% similar) in 2265 aa overlap (1-2265:1-2240) 10 20 30 40 50 60 pF1KB0 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: CCDS77 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDTTVDQVDDTSIVVRWSRPQAPITG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB0 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB0 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB0 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB0 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB0 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB0 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI ::::::::::::::::::::::::::::::::::::::::: CCDS77 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT------------------- 1870 1880 1890 1900 1930 1940 1950 1960 1970 1980 pF1KB0 LDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIR :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 ------VQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIR 1910 1920 1930 1940 1950 1990 2000 2010 2020 2030 2040 pF1KB0 HRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 HRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTG 1960 1970 1980 1990 2000 2010 2050 2060 2070 2080 2090 2100 pF1KB0 LTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEW ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LTRGATYNVIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEW 2020 2030 2040 2050 2060 2070 2110 2120 2130 2140 2150 2160 pF1KB0 ERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 ERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGN 2080 2090 2100 2110 2120 2130 2170 2180 2190 2200 2210 2220 pF1KB0 GKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 GKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPS 2140 2150 2160 2170 2180 2190 2230 2240 2250 2260 pF1KB0 PEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE ::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2200 2210 2220 2230 2240 >>CCDS77525.1 FN1 gene_id:2335|Hs108|chr2 (2267 aa) initn: 11376 init1: 8984 opt: 11845 Z-score: 9846.7 bits: 1835.8 E(32554): 0 Smith-Waterman score: 14562; 92.3% identity (92.3% similar) in 2356 aa overlap (1-2265:1-2267) 10 20 30 40 50 60 pF1KB0 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: CCDS77 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDTTVDQVDDTSIVVRWSRPQAPITG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1210 1220 1230 1240 1250 1260 pF1KB0 DTIIP------------------------------------------------------- ::::: CCDS77 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1270 1280 1290 1300 1310 1320 1270 1280 pF1KB0 ------------------------------------AVPPPTDLRFTNIGPDTMRVTWAP :::::::::::::::::::::::: CCDS77 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1330 1340 1350 1360 1370 1380 1290 1300 1310 1320 1330 1340 pF1KB0 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1390 1400 1410 1420 1430 1440 1350 1360 1370 1380 1390 1400 pF1KB0 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1450 1460 1470 1480 1490 1500 1410 1420 1430 1440 1450 1460 pF1KB0 RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD 1510 1520 1530 1540 1550 1560 1470 1480 1490 1500 1510 1520 pF1KB0 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1570 1580 1590 1600 1610 1620 1530 1540 1550 1560 1570 1580 pF1KB0 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1630 1640 1650 1660 1670 1680 1590 1600 1610 1620 1630 1640 pF1KB0 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLS 1690 1700 1710 1720 1730 1740 1650 1660 1670 1680 1690 1700 pF1KB0 AQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 AQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTL 1750 1760 1770 1780 1790 1800 1710 1720 1730 1740 1750 1760 pF1KB0 TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQR 1810 1820 1830 1840 1850 1860 1770 1780 1790 1800 1810 1820 pF1KB0 TIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 TIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSL 1870 1880 1890 1900 1910 1920 1830 1840 1850 1860 1870 1880 pF1KB0 LVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNN 1930 1940 1950 1960 1970 1980 1890 1900 1910 1920 1930 1940 pF1KB0 QKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGT :::::::::::: CCDS77 QKSEPLIGRKKT------------------------------------------------ 1990 1950 1960 1970 1980 1990 2000 pF1KB0 SGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTS ::::::::::::::::::: CCDS77 -----------------------------------------GQEALSQTTISWAPFQDTS 2000 2010 2010 2020 2030 2040 2050 2060 pF1KB0 EYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTV :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: CCDS77 EYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNVIVEALKDQQRHKVREEVVTV 2020 2030 2040 2050 2060 2070 2070 2080 2090 2100 2110 2120 pF1KB0 GNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 GNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRW 2080 2090 2100 2110 2120 2130 2130 2140 2150 2160 2170 2180 pF1KB0 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQK 2140 2150 2160 2170 2180 2190 2190 2200 2210 2220 2230 2240 pF1KB0 EYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 EYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIE 2200 2210 2220 2230 2240 2250 2250 2260 pF1KB0 CFMPLDVQADREDSRE :::::::::::::::: CCDS77 CFMPLDVQADREDSRE 2260 >>CCDS2399.1 FN1 gene_id:2335|Hs108|chr2 (2355 aa) initn: 11325 init1: 11325 opt: 11675 Z-score: 9705.1 bits: 1809.7 E(32554): 0 Smith-Waterman score: 14953; 96.0% identity (96.0% similar) in 2297 aa overlap (1-2207:1-2297) 10 20 30 40 50 60 pF1KB0 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: CCDS23 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDTTVDQVDDTSIVVRWSRPQAPITG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB0 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1570 1580 1590 1600 1610 1620 1630 pF1KB0 SQPLVQTAVTTI------------------------------------------------ ::::::::::.: CCDS23 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1630 1640 1650 1660 1670 1680 1640 1650 pF1KB0 ------------------------------------------PAPTDLKFTQVTPTSLSA :::::::::::::::::: CCDS23 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1690 1700 1710 1720 1730 1740 1660 1670 1680 1690 1700 1710 pF1KB0 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1750 1760 1770 1780 1790 1800 1720 1730 1740 1750 1760 1770 pF1KB0 SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT 1810 1820 1830 1840 1850 1860 1780 1790 1800 1810 1820 1830 pF1KB0 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL 1870 1880 1890 1900 1910 1920 1840 1850 1860 1870 1880 1890 pF1KB0 VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ 1930 1940 1950 1960 1970 1980 1900 1910 1920 1930 1940 1950 pF1KB0 KSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 KSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTS 1990 2000 2010 2020 2030 2040 1960 1970 1980 1990 2000 2010 pF1KB0 GQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 GQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSE 2050 2060 2070 2080 2090 2100 2020 2030 2040 2050 2060 2070 pF1KB0 YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVG ::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::: CCDS23 YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNVIVEALKDQQRHKVREEVVTVG 2110 2120 2130 2140 2150 2160 2080 2090 2100 2110 2120 2130 pF1KB0 NSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 NSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWC 2170 2180 2190 2200 2210 2220 2140 2150 2160 2170 2180 2190 pF1KB0 HDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 HDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKE 2230 2240 2250 2260 2270 2280 2200 2210 2220 2230 2240 2250 pF1KB0 YLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIEC ::::::::::::::::: CCDS23 YLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIEC 2290 2300 2310 2320 2330 2340 >-- initn: 429 init1: 429 opt: 429 Z-score: 355.1 bits: 79.6 E(32554): 1.8e-13 Smith-Waterman score: 429; 100.0% identity (100.0% similar) in 58 aa overlap (2208-2265:2298-2355) 2180 2190 2200 2210 2220 2230 pF1KB0 GKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYH :::::::::::::::::::::::::::::: CCDS23 GKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYH 2270 2280 2290 2300 2310 2320 2240 2250 2260 pF1KB0 QRTNTNVNCPIECFMPLDVQADREDSRE :::::::::::::::::::::::::::: CCDS23 QRTNTNVNCPIECFMPLDVQADREDSRE 2330 2340 2350 >>CCDS46510.1 FN1 gene_id:2335|Hs108|chr2 (2330 aa) initn: 13793 init1: 11325 opt: 11638 Z-score: 9674.4 bits: 1804.0 E(32554): 0 Smith-Waterman score: 14911; 94.9% identity (95.0% similar) in 2322 aa overlap (1-2232:1-2297) 10 20 30 40 50 60 pF1KB0 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: CCDS46 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDTTVDQVDDTSIVVRWSRPQAPITG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB0 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1570 1580 1590 1600 1610 1620 1630 pF1KB0 SQPLVQTAVTTI------------------------------------------------ ::::::::::.: CCDS46 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1630 1640 1650 1660 1670 1680 1640 1650 pF1KB0 ------------------------------------------PAPTDLKFTQVTPTSLSA :::::::::::::::::: CCDS46 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1690 1700 1710 1720 1730 1740 1660 1670 1680 1690 1700 1710 pF1KB0 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1750 1760 1770 1780 1790 1800 1720 1730 1740 1750 1760 1770 pF1KB0 SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT 1810 1820 1830 1840 1850 1860 1780 1790 1800 1810 1820 1830 pF1KB0 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL 1870 1880 1890 1900 1910 1920 1840 1850 1860 1870 1880 1890 pF1KB0 VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ 1930 1940 1950 1960 1970 1980 1900 1910 1920 1930 1940 1950 pF1KB0 KSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTS ::::::::::: :::::::::::::::::::::::: CCDS46 KSEPLIGRKKT-------------------------VQKTPFVTHPGYDTGNGIQLPGTS 1990 2000 2010 1960 1970 1980 1990 2000 2010 pF1KB0 GQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 GQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSE 2020 2030 2040 2050 2060 2070 2020 2030 2040 2050 2060 2070 pF1KB0 YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVG ::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::: CCDS46 YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNVIVEALKDQQRHKVREEVVTVG 2080 2090 2100 2110 2120 2130 2080 2090 2100 2110 2120 2130 pF1KB0 NSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 NSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWC 2140 2150 2160 2170 2180 2190 2140 2150 2160 2170 2180 2190 pF1KB0 HDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 HDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKE 2200 2210 2220 2230 2240 2250 2200 2210 2220 2230 2240 2250 pF1KB0 YLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIEC :::::::::::::::::::::::::::::::::::::::::: CCDS46 YLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIEC 2260 2270 2280 2290 2300 2310 2260 pF1KB0 FMPLDVQADREDSRE CCDS46 FMPLDVQADREDSRE 2320 2330 >>CCDS77526.1 FN1 gene_id:2335|Hs108|chr2 (2446 aa) initn: 9379 init1: 8984 opt: 9889 Z-score: 8219.9 bits: 1534.9 E(32554): 0 Smith-Waterman score: 14040; 92.0% identity (92.1% similar) in 2297 aa overlap (1-2116:1-2297) 10 20 30 40 50 60 pF1KB0 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: CCDS77 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDTTVDQVDDTSIVVRWSRPQAPITG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1210 1220 1230 1240 1250 1260 pF1KB0 DTIIP------------------------------------------------------- ::::: CCDS77 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1270 1280 1290 1300 1310 1320 1270 1280 pF1KB0 ------------------------------------AVPPPTDLRFTNIGPDTMRVTWAP :::::::::::::::::::::::: CCDS77 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1330 1340 1350 1360 1370 1380 1290 1300 1310 1320 1330 1340 pF1KB0 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1390 1400 1410 1420 1430 1440 1350 1360 1370 1380 1390 1400 pF1KB0 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1450 1460 1470 1480 1490 1500 1410 1420 1430 1440 1450 1460 pF1KB0 RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD 1510 1520 1530 1540 1550 1560 1470 1480 1490 1500 1510 1520 pF1KB0 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1570 1580 1590 1600 1610 1620 1530 1540 1550 1560 1570 1580 pF1KB0 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1630 1640 1650 1660 1670 1680 1590 1600 1610 1620 1630 pF1KB0 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTI----------------- :::::::::::::::::::::::::::::::::::::::::.: CCDS77 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIK 1690 1700 1710 1720 1730 1740 pF1KB0 ------------------------------------------------------------ CCDS77 IAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDM 1750 1760 1770 1780 1790 1800 1640 1650 1660 1670 pF1KB0 -------------PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN ::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 ESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN 1810 1820 1830 1840 1850 1860 1680 1690 1700 1710 1720 1730 pF1KB0 LAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT 1870 1880 1890 1900 1910 1920 1740 1750 1760 1770 1780 1790 pF1KB0 ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN 1930 1940 1950 1960 1970 1980 1800 1810 1820 1830 1840 1850 pF1KB0 ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP 1990 2000 2010 2020 2030 2040 1860 1870 1880 1890 1900 1910 pF1KB0 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPE 2050 2060 2070 2080 2090 2100 1920 1930 1940 1950 1960 1970 pF1KB0 ILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 ILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPI 2110 2120 2130 2140 2150 2160 1980 1990 2000 2010 2020 2030 pF1KB0 RHRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 RHRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLT 2170 2180 2190 2200 2210 2220 2040 2050 2060 2070 2080 2090 pF1KB0 GLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDE :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 GLTRGATYNVIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDE 2230 2240 2250 2260 2270 2280 2100 2110 2120 2130 2140 2150 pF1KB0 WERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLG ::::::::::::::::: CCDS77 WERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLG 2290 2300 2310 2320 2330 2340 >-- initn: 1150 init1: 1150 opt: 1150 Z-score: 954.3 bits: 190.6 E(32554): 7.8e-47 Smith-Waterman score: 1150; 100.0% identity (100.0% similar) in 149 aa overlap (2117-2265:2298-2446) 2090 2100 2110 2120 2130 2140 pF1KB0 DPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQ :::::::::::::::::::::::::::::: CCDS77 DPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQ 2270 2280 2290 2300 2310 2320 2150 2160 2170 2180 2190 2200 pF1KB0 GENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 GENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRG 2330 2340 2350 2360 2370 2380 2210 2220 2230 2240 2250 2260 pF1KB0 WRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 WRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2390 2400 2410 2420 2430 2440 >>CCDS42814.1 FN1 gene_id:2335|Hs108|chr2 (2477 aa) initn: 12116 init1: 8984 opt: 9889 Z-score: 8219.9 bits: 1534.9 E(32554): 0 Smith-Waterman score: 13740; 90.6% identity (90.7% similar) in 2297 aa overlap (1-2085:1-2297) 10 20 30 40 50 60 pF1KB0 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: CCDS42 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDTTVDQVDDTSIVVRWSRPQAPITG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1210 1220 1230 1240 1250 1260 pF1KB0 DTIIP------------------------------------------------------- ::::: CCDS42 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1270 1280 1290 1300 1310 1320 1270 1280 pF1KB0 ------------------------------------AVPPPTDLRFTNIGPDTMRVTWAP :::::::::::::::::::::::: CCDS42 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1330 1340 1350 1360 1370 1380 1290 1300 1310 1320 1330 1340 pF1KB0 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1390 1400 1410 1420 1430 1440 1350 1360 1370 1380 1390 1400 pF1KB0 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1450 1460 1470 1480 1490 1500 1410 1420 1430 1440 1450 1460 pF1KB0 RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD 1510 1520 1530 1540 1550 1560 1470 1480 1490 1500 1510 1520 pF1KB0 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1570 1580 1590 1600 1610 1620 1530 1540 1550 1560 1570 1580 pF1KB0 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1630 1640 1650 1660 1670 1680 1590 1600 1610 1620 1630 pF1KB0 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTI----------------- :::::::::::::::::::::::::::::::::::::::::.: CCDS42 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIK 1690 1700 1710 1720 1730 1740 pF1KB0 ------------------------------------------------------------ CCDS42 IAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDM 1750 1760 1770 1780 1790 1800 1640 1650 1660 1670 pF1KB0 -------------PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN ::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 ESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN 1810 1820 1830 1840 1850 1860 1680 1690 1700 1710 1720 1730 pF1KB0 LAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT 1870 1880 1890 1900 1910 1920 1740 1750 1760 1770 1780 1790 pF1KB0 ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN 1930 1940 1950 1960 1970 1980 1800 1810 1820 1830 1840 1850 pF1KB0 ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP 1990 2000 2010 2020 2030 2040 1860 1870 1880 1890 1900 1910 pF1KB0 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPE 2050 2060 2070 2080 2090 2100 1920 1930 1940 1950 1960 1970 pF1KB0 ILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 ILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPI 2110 2120 2130 2140 2150 2160 1980 1990 2000 pF1KB0 RHRPRPYPPNVG-------------------------------QEALSQTTISWAPFQDT :::::::::::: ::::::::::::::::: CCDS42 RHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDT 2170 2180 2190 2200 2210 2220 2010 2020 2030 2040 2050 2060 pF1KB0 SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVT ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: CCDS42 SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNVIVEALKDQQRHKVREEVVT 2230 2240 2250 2260 2270 2280 2070 2080 2090 2100 2110 2120 pF1KB0 VGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSR ::::::::::::::::: CCDS42 VGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSR 2290 2300 2310 2320 2330 2340 >-- initn: 1378 init1: 1378 opt: 1378 Z-score: 1143.8 bits: 225.6 E(32554): 2.2e-57 Smith-Waterman score: 1378; 100.0% identity (100.0% similar) in 180 aa overlap (2086-2265:2298-2477) 2060 2070 2080 2090 2100 2110 pF1KB0 DQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCL :::::::::::::::::::::::::::::: CCDS42 DQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCL 2270 2280 2290 2300 2310 2320 2120 2130 2140 2150 2160 2170 pF1KB0 GFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 GFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCY 2330 2340 2350 2360 2370 2380 2180 2190 2200 2210 2220 2230 pF1KB0 DDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 DDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQR 2390 2400 2410 2420 2430 2440 2240 2250 2260 pF1KB0 YHQRTNTNVNCPIECFMPLDVQADREDSRE :::::::::::::::::::::::::::::: CCDS42 YHQRTNTNVNCPIECFMPLDVQADREDSRE 2450 2460 2470 >>CCDS46512.1 FN1 gene_id:2335|Hs108|chr2 (657 aa) initn: 4805 init1: 4805 opt: 4805 Z-score: 4001.5 bits: 752.5 E(32554): 1.4e-216 Smith-Waterman score: 4805; 100.0% identity (100.0% similar) in 647 aa overlap (1-647:1-647) 10 20 30 40 50 60 pF1KB0 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP ::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPVSIPPRNLGY 610 620 630 640 650 670 680 690 700 710 720 pF1KB0 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 2265 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 11:30:16 2016 done: Thu Nov 3 11:30:18 2016 Total Scan time: 6.150 Total Display time: 2.370 Function used was FASTA [36.3.4 Apr, 2011]