FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0006, 2265 aa 1>>>pF1KB0006 2265 - 2265 aa - 2265 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.8348+/-0.000485; mu= -4.7473+/- 0.030 mean_var=210.2363+/-42.924, 0's: 0 Z-trim(114.9): 319 B-trim: 486 in 1/57 Lambda= 0.088455 statistics sampled from 24597 (24969) to 24597 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.615), E-opt: 0.2 (0.293), width: 16 Scan time: 21.930 The best scores are: opt bits E(85289) NP_001293060 (OMIM: 135600,601894,614101) fibronec (2265) 15589 2004.2 0 XP_005246469 (OMIM: 135600,601894,614101) PREDICTE (2271) 14932 1920.3 0 NP_997641 (OMIM: 135600,601894,614101) fibronectin (2296) 13608 1751.4 0 XP_005246471 (OMIM: 135600,601894,614101) PREDICTE (2266) 13601 1750.5 0 XP_016859184 (OMIM: 135600,601894,614101) PREDICTE (2302) 13597 1750.0 0 NP_997639 (OMIM: 135600,601894,614101) fibronectin (2176) 13002 1674.0 0 NP_001293061 (OMIM: 135600,601894,614101) fibronec (2240) 12979 1671.1 0 XP_005246473 (OMIM: 135600,601894,614101) PREDICTE (2246) 12968 1669.7 0 NP_001293059 (OMIM: 135600,601894,614101) fibronec (2267) 11857 1527.9 0 NP_002017 (OMIM: 135600,601894,614101) fibronectin (2355) 11686 1506.1 0 XP_005246468 (OMIM: 135600,601894,614101) PREDICTE (2273) 11680 1505.3 0 NP_997643 (OMIM: 135600,601894,614101) fibronectin (2330) 11649 1501.4 0 XP_005246466 (OMIM: 135600,601894,614101) PREDICTE (2361) 11638 1500.0 0 XP_005246463 (OMIM: 135600,601894,614101) PREDICTE (2386) 11638 1500.0 0 XP_005246461 (OMIM: 135600,601894,614101) PREDICTE (2392) 11638 1500.0 0 XP_016859181 (OMIM: 135600,601894,614101) PREDICTE (2357) 9924 1281.3 0 XP_005246464 (OMIM: 135600,601894,614101) PREDICTE (2363) 9924 1281.3 0 XP_016859182 (OMIM: 135600,601894,614101) PREDICTE (2356) 9919 1280.6 0 XP_005246465 (OMIM: 135600,601894,614101) PREDICTE (2362) 9919 1280.6 0 NP_001293058 (OMIM: 135600,601894,614101) fibronec (2446) 9900 1278.2 0 NP_997647 (OMIM: 135600,601894,614101) fibronectin (2477) 9900 1278.2 0 XP_005246459 (OMIM: 135600,601894,614101) PREDICTE (2421) 9889 1276.8 0 XP_005246458 (OMIM: 135600,601894,614101) PREDICTE (2427) 9889 1276.8 0 XP_005246456 (OMIM: 135600,601894,614101) PREDICTE (2452) 9889 1276.8 0 XP_005246455 (OMIM: 135600,601894,614101) PREDICTE (2458) 9889 1276.8 0 XP_005246454 (OMIM: 135600,601894,614101) PREDICTE (2483) 9889 1276.8 0 XP_016859183 (OMIM: 135600,601894,614101) PREDICTE (2331) 9882 1275.9 0 XP_005246467 (OMIM: 135600,601894,614101) PREDICTE (2337) 9882 1275.9 0 XP_005246462 (OMIM: 135600,601894,614101) PREDICTE (2387) 9882 1275.9 0 XP_005246460 (OMIM: 135600,601894,614101) PREDICTE (2393) 9882 1275.9 0 NP_473375 (OMIM: 135600,601894,614101) fibronectin ( 657) 4805 627.9 1.2e-178 XP_016861181 (OMIM: 120120,131705,131750,131850,13 (2452) 790 115.6 7.3e-24 XP_016861180 (OMIM: 120120,131705,131750,131850,13 (2466) 790 115.6 7.4e-24 XP_016861179 (OMIM: 120120,131705,131750,131850,13 (2470) 790 115.6 7.4e-24 XP_016861178 (OMIM: 120120,131705,131750,131850,13 (2609) 790 115.6 7.8e-24 XP_016861177 (OMIM: 120120,131705,131750,131850,13 (2924) 790 115.6 8.7e-24 NP_000085 (OMIM: 120120,131705,131750,131850,13200 (2944) 790 115.6 8.7e-24 XP_011531639 (OMIM: 120120,131705,131750,131850,13 (2944) 790 115.6 8.7e-24 NP_542376 (OMIM: 120320,616470,616471) collagen al (1899) 747 110.1 2.6e-22 XP_011533738 (OMIM: 120320,616470,616471) PREDICTE (1954) 747 110.1 2.6e-22 XP_005252032 (OMIM: 187380,615629) PREDICTED: tena (1564) 597 91.0 1.2e-16 XP_006717164 (OMIM: 187380,615629) PREDICTED: tena (1655) 583 89.2 4.5e-16 XP_005252031 (OMIM: 187380,615629) PREDICTED: tena (1655) 583 89.2 4.5e-16 XP_011516930 (OMIM: 187380,615629) PREDICTED: tena (1746) 583 89.2 4.7e-16 XP_005252030 (OMIM: 187380,615629) PREDICTED: tena (1837) 583 89.2 5e-16 XP_006717161 (OMIM: 187380,615629) PREDICTED: tena (2019) 583 89.2 5.4e-16 XP_011516927 (OMIM: 187380,615629) PREDICTED: tena (2019) 583 89.2 5.4e-16 XP_011516931 (OMIM: 187380,615629) PREDICTED: tena (1746) 581 88.9 5.7e-16 XP_005252029 (OMIM: 187380,615629) PREDICTED: tena (2110) 583 89.2 5.7e-16 XP_006717160 (OMIM: 187380,615629) PREDICTED: tena (2110) 583 89.2 5.7e-16 >>NP_001293060 (OMIM: 135600,601894,614101) fibronectin (2265 aa) initn: 15589 init1: 15589 opt: 15589 Z-score: 10756.5 bits: 2004.2 E(85289): 0 Smith-Waterman score: 15589; 100.0% identity (100.0% similar) in 2265 aa overlap (1-2265:1-2265) 10 20 30 40 50 60 pF1KB0 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB0 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB0 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB0 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB0 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB0 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB0 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KB0 LDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIR 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KB0 HRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTG 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KB0 LTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEW 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KB0 ERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGN 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KB0 GKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPS 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 pF1KB0 PEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE ::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2230 2240 2250 2260 >>XP_005246469 (OMIM: 135600,601894,614101) PREDICTED: f (2271 aa) initn: 15576 init1: 12952 opt: 14932 Z-score: 10303.4 bits: 1920.3 E(85289): 0 Smith-Waterman score: 15270; 97.5% identity (97.5% similar) in 2296 aa overlap (1-2265:1-2271) 10 20 30 40 50 60 pF1KB0 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_005 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDTTVDQVDDTSIVVRWSRPQAPITG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB0 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB0 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB0 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB0 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB0 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB0 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI ::::::::::::::::::::::::::::::::::::::::: XP_005 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT------------------- 1870 1880 1890 1900 1930 1940 1950 1960 1970 1980 pF1KB0 LDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIR :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ------VQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIR 1910 1920 1930 1940 1950 1990 2000 pF1KB0 HRPRPYPPNVG-------------------------------QEALSQTTISWAPFQDTS ::::::::::: :::::::::::::::::: XP_005 HRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTS 1960 1970 1980 1990 2000 2010 2010 2020 2030 2040 2050 2060 pF1KB0 EYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTV :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: XP_005 EYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNVIVEALKDQQRHKVREEVVTV 2020 2030 2040 2050 2060 2070 2070 2080 2090 2100 2110 2120 pF1KB0 GNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRW 2080 2090 2100 2110 2120 2130 2130 2140 2150 2160 2170 2180 pF1KB0 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQK 2140 2150 2160 2170 2180 2190 2190 2200 2210 2220 2230 2240 pF1KB0 EYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIE 2200 2210 2220 2230 2240 2250 2250 2260 pF1KB0 CFMPLDVQADREDSRE :::::::::::::::: XP_005 CFMPLDVQADREDSRE 2260 2270 >>NP_997641 (OMIM: 135600,601894,614101) fibronectin iso (2296 aa) initn: 14239 init1: 13603 opt: 13608 Z-score: 9390.2 bits: 1751.4 E(85289): 0 Smith-Waterman score: 15517; 98.6% identity (98.6% similar) in 2296 aa overlap (1-2265:1-2296) 10 20 30 40 50 60 pF1KB0 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB0 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB0 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB0 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB0 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB0 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB0 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KB0 LDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 LDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIR 1930 1940 1950 1960 1970 1980 1990 2000 pF1KB0 HRPRPYPPNVG-------------------------------QEALSQTTISWAPFQDTS ::::::::::: :::::::::::::::::: NP_997 HRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTS 1990 2000 2010 2020 2030 2040 2010 2020 2030 2040 2050 2060 pF1KB0 EYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 EYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTV 2050 2060 2070 2080 2090 2100 2070 2080 2090 2100 2110 2120 pF1KB0 GNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 GNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRW 2110 2120 2130 2140 2150 2160 2130 2140 2150 2160 2170 2180 pF1KB0 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQK 2170 2180 2190 2200 2210 2220 2190 2200 2210 2220 2230 2240 pF1KB0 EYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 EYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIE 2230 2240 2250 2260 2270 2280 2250 2260 pF1KB0 CFMPLDVQADREDSRE :::::::::::::::: NP_997 CFMPLDVQADREDSRE 2290 >>XP_005246471 (OMIM: 135600,601894,614101) PREDICTED: f (2266 aa) initn: 13312 init1: 11325 opt: 13601 Z-score: 9385.4 bits: 1750.5 E(85289): 0 Smith-Waterman score: 14559; 92.3% identity (92.4% similar) in 2355 aa overlap (1-2265:1-2266) 10 20 30 40 50 60 pF1KB0 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_005 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDTTVDQVDDTSIVVRWSRPQAPITG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB0 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1570 1580 1590 1600 1610 1620 1630 pF1KB0 SQPLVQTAVTTI------------------------------------------------ ::::::::::.: XP_005 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1630 1640 1650 1660 1670 1680 1640 1650 pF1KB0 ------------------------------------------PAPTDLKFTQVTPTSLSA :::::::::::::::::: XP_005 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1690 1700 1710 1720 1730 1740 1660 1670 1680 1690 1700 1710 pF1KB0 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1750 1760 1770 1780 1790 1800 1720 1730 1740 1750 1760 1770 pF1KB0 SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT 1810 1820 1830 1840 1850 1860 1780 1790 1800 1810 1820 1830 pF1KB0 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL 1870 1880 1890 1900 1910 1920 1840 1850 1860 1870 1880 1890 pF1KB0 VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ 1930 1940 1950 1960 1970 1980 1900 1910 1920 1930 1940 1950 pF1KB0 KSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTS ::::::::::: XP_005 KSEPLIGRKKT------------------------------------------------- 1990 1960 1970 1980 1990 2000 2010 pF1KB0 GQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSE :::::::::::::::::::: XP_005 ----------------------------------------GQEALSQTTISWAPFQDTSE 2000 2010 2020 2030 2040 2050 2060 2070 pF1KB0 YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVG ::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::: XP_005 YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNVIVEALKDQQRHKVREEVVTVG 2020 2030 2040 2050 2060 2070 2080 2090 2100 2110 2120 2130 pF1KB0 NSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWC 2080 2090 2100 2110 2120 2130 2140 2150 2160 2170 2180 2190 pF1KB0 HDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKE 2140 2150 2160 2170 2180 2190 2200 2210 2220 2230 2240 2250 pF1KB0 YLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIEC 2200 2210 2220 2230 2240 2250 2260 pF1KB0 FMPLDVQADREDSRE ::::::::::::::: XP_005 FMPLDVQADREDSRE 2260 >>XP_016859184 (OMIM: 135600,601894,614101) PREDICTED: f (2302 aa) initn: 14228 init1: 13592 opt: 13597 Z-score: 9382.6 bits: 1750.0 E(85289): 0 Smith-Waterman score: 15340; 98.1% identity (98.2% similar) in 2287 aa overlap (1-2255:1-2287) 10 20 30 40 50 60 pF1KB0 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_016 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDTTVDQVDDTSIVVRWSRPQAPITG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB0 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB0 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB0 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB0 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB0 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB0 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KB0 LDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIR 1930 1940 1950 1960 1970 1980 1990 2000 pF1KB0 HRPRPYPPNVG-------------------------------QEALSQTTISWAPFQDTS ::::::::::: :::::::::::::::::: XP_016 HRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTS 1990 2000 2010 2020 2030 2040 2010 2020 2030 2040 2050 2060 pF1KB0 EYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTV :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: XP_016 EYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNVIVEALKDQQRHKVREEVVTV 2050 2060 2070 2080 2090 2100 2070 2080 2090 2100 2110 2120 pF1KB0 GNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRW 2110 2120 2130 2140 2150 2160 2130 2140 2150 2160 2170 2180 pF1KB0 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQK 2170 2180 2190 2200 2210 2220 2190 2200 2210 2220 2230 2240 pF1KB0 EYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIE ::::::::::::::::::::::::::::::::::::::::::::::::::::: . XP_016 EYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTVSALAAQ 2230 2240 2250 2260 2270 2280 2250 2260 pF1KB0 -CFMPLDVQADREDSRE : . :: XP_016 VCSLILDSLFLQVSFFRMNQVF 2290 2300 >>NP_997639 (OMIM: 135600,601894,614101) fibronectin iso (2176 aa) initn: 12953 init1: 12953 opt: 13002 Z-score: 8972.6 bits: 1674.0 E(85289): 0 Smith-Waterman score: 14766; 96.1% identity (96.1% similar) in 2265 aa overlap (1-2265:1-2176) 10 20 30 40 50 60 pF1KB0 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB0 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB0 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB0 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB0 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB0 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB0 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI ::::::::::::::::::::::::::::::::::::::::: NP_997 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT------------------- 1870 1880 1890 1900 1930 1940 1950 1960 1970 1980 pF1KB0 LDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIR NP_997 ------------------------------------------------------------ 1990 2000 2010 2020 2030 2040 pF1KB0 HRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTG :::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 ----------GQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTG 1910 1920 1930 1940 1950 2050 2060 2070 2080 2090 2100 pF1KB0 LTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 LTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEW 1960 1970 1980 1990 2000 2010 2110 2120 2130 2140 2150 2160 pF1KB0 ERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 ERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGN 2020 2030 2040 2050 2060 2070 2170 2180 2190 2200 2210 2220 pF1KB0 GKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 GKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPS 2080 2090 2100 2110 2120 2130 2230 2240 2250 2260 pF1KB0 PEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE ::::::::::::::::::::::::::::::::::::::::::::: NP_997 PEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2140 2150 2160 2170 >>NP_001293061 (OMIM: 135600,601894,614101) fibronectin (2240 aa) initn: 13599 init1: 12963 opt: 12979 Z-score: 8956.5 bits: 1671.1 E(85289): 0 Smith-Waterman score: 15354; 98.9% identity (98.9% similar) in 2265 aa overlap (1-2265:1-2240) 10 20 30 40 50 60 pF1KB0 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB0 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB0 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB0 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB0 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB0 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB0 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI ::::::::::::::::::::::::::::::::::::::::: NP_001 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT------------------- 1870 1880 1890 1900 1930 1940 1950 1960 1970 1980 pF1KB0 LDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIR :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ------VQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIR 1910 1920 1930 1940 1950 1990 2000 2010 2020 2030 2040 pF1KB0 HRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTG 1960 1970 1980 1990 2000 2010 2050 2060 2070 2080 2090 2100 pF1KB0 LTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEW 2020 2030 2040 2050 2060 2070 2110 2120 2130 2140 2150 2160 pF1KB0 ERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGN 2080 2090 2100 2110 2120 2130 2170 2180 2190 2200 2210 2220 pF1KB0 GKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPS 2140 2150 2160 2170 2180 2190 2230 2240 2250 2260 pF1KB0 PEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE ::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2200 2210 2220 2230 2240 >>XP_005246473 (OMIM: 135600,601894,614101) PREDICTED: f (2246 aa) initn: 13588 init1: 12952 opt: 12968 Z-score: 8948.9 bits: 1669.7 E(85289): 0 Smith-Waterman score: 15177; 98.3% identity (98.4% similar) in 2256 aa overlap (1-2255:1-2231) 10 20 30 40 50 60 pF1KB0 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_005 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDTTVDQVDDTSIVVRWSRPQAPITG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB0 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB0 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB0 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB0 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB0 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPR 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB0 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI ::::::::::::::::::::::::::::::::::::::::: XP_005 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT------------------- 1870 1880 1890 1900 1930 1940 1950 1960 1970 1980 pF1KB0 LDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIR :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ------VQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIR 1910 1920 1930 1940 1950 1990 2000 2010 2020 2030 2040 pF1KB0 HRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTG 1960 1970 1980 1990 2000 2010 2050 2060 2070 2080 2090 2100 pF1KB0 LTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEW ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LTRGATYNVIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEW 2020 2030 2040 2050 2060 2070 2110 2120 2130 2140 2150 2160 pF1KB0 ERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGN 2080 2090 2100 2110 2120 2130 2170 2180 2190 2200 2210 2220 pF1KB0 GKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPS 2140 2150 2160 2170 2180 2190 2230 2240 2250 2260 pF1KB0 PEGTTGQSYNQYSQRYHQRTNTNVNCPIE-CFMPLDVQADREDSRE :::::::::::::::::::::: . : . :: XP_005 PEGTTGQSYNQYSQRYHQRTNTVSALAAQVCSLILDSLFLQVSFFRMNQVF 2200 2210 2220 2230 2240 >>NP_001293059 (OMIM: 135600,601894,614101) fibronectin (2267 aa) initn: 11388 init1: 8995 opt: 11857 Z-score: 8182.6 bits: 1527.9 E(85289): 0 Smith-Waterman score: 14574; 92.4% identity (92.4% similar) in 2356 aa overlap (1-2265:1-2267) 10 20 30 40 50 60 pF1KB0 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1210 1220 1230 1240 1250 1260 pF1KB0 DTIIP------------------------------------------------------- ::::: NP_001 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1270 1280 1290 1300 1310 1320 1270 1280 pF1KB0 ------------------------------------AVPPPTDLRFTNIGPDTMRVTWAP :::::::::::::::::::::::: NP_001 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1330 1340 1350 1360 1370 1380 1290 1300 1310 1320 1330 1340 pF1KB0 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1390 1400 1410 1420 1430 1440 1350 1360 1370 1380 1390 1400 pF1KB0 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1450 1460 1470 1480 1490 1500 1410 1420 1430 1440 1450 1460 pF1KB0 RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD 1510 1520 1530 1540 1550 1560 1470 1480 1490 1500 1510 1520 pF1KB0 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1570 1580 1590 1600 1610 1620 1530 1540 1550 1560 1570 1580 pF1KB0 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1630 1640 1650 1660 1670 1680 1590 1600 1610 1620 1630 1640 pF1KB0 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLS 1690 1700 1710 1720 1730 1740 1650 1660 1670 1680 1690 1700 pF1KB0 AQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTL 1750 1760 1770 1780 1790 1800 1710 1720 1730 1740 1750 1760 pF1KB0 TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQR 1810 1820 1830 1840 1850 1860 1770 1780 1790 1800 1810 1820 pF1KB0 TIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSL 1870 1880 1890 1900 1910 1920 1830 1840 1850 1860 1870 1880 pF1KB0 LVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNN 1930 1940 1950 1960 1970 1980 1890 1900 1910 1920 1930 1940 pF1KB0 QKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGT :::::::::::: NP_001 QKSEPLIGRKKT------------------------------------------------ 1990 1950 1960 1970 1980 1990 2000 pF1KB0 SGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTS ::::::::::::::::::: NP_001 -----------------------------------------GQEALSQTTISWAPFQDTS 2000 2010 2010 2020 2030 2040 2050 2060 pF1KB0 EYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTV 2020 2030 2040 2050 2060 2070 2070 2080 2090 2100 2110 2120 pF1KB0 GNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRW 2080 2090 2100 2110 2120 2130 2130 2140 2150 2160 2170 2180 pF1KB0 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQK 2140 2150 2160 2170 2180 2190 2190 2200 2210 2220 2230 2240 pF1KB0 EYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIE 2200 2210 2220 2230 2240 2250 2250 2260 pF1KB0 CFMPLDVQADREDSRE :::::::::::::::: NP_001 CFMPLDVQADREDSRE 2260 >>NP_002017 (OMIM: 135600,601894,614101) fibronectin iso (2355 aa) initn: 11336 init1: 11336 opt: 11686 Z-score: 8064.4 bits: 1506.1 E(85289): 0 Smith-Waterman score: 14965; 96.0% identity (96.1% similar) in 2297 aa overlap (1-2207:1-2297) 10 20 30 40 50 60 pF1KB0 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB0 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1570 1580 1590 1600 1610 1620 1630 pF1KB0 SQPLVQTAVTTI------------------------------------------------ ::::::::::.: NP_002 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1630 1640 1650 1660 1670 1680 1640 1650 pF1KB0 ------------------------------------------PAPTDLKFTQVTPTSLSA :::::::::::::::::: NP_002 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1690 1700 1710 1720 1730 1740 1660 1670 1680 1690 1700 1710 pF1KB0 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1750 1760 1770 1780 1790 1800 1720 1730 1740 1750 1760 1770 pF1KB0 SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT 1810 1820 1830 1840 1850 1860 1780 1790 1800 1810 1820 1830 pF1KB0 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL 1870 1880 1890 1900 1910 1920 1840 1850 1860 1870 1880 1890 pF1KB0 VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ 1930 1940 1950 1960 1970 1980 1900 1910 1920 1930 1940 1950 pF1KB0 KSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTS 1990 2000 2010 2020 2030 2040 1960 1970 1980 1990 2000 2010 pF1KB0 GQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSE 2050 2060 2070 2080 2090 2100 2020 2030 2040 2050 2060 2070 pF1KB0 YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVG 2110 2120 2130 2140 2150 2160 2080 2090 2100 2110 2120 2130 pF1KB0 NSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWC 2170 2180 2190 2200 2210 2220 2140 2150 2160 2170 2180 2190 pF1KB0 HDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 HDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKE 2230 2240 2250 2260 2270 2280 2200 2210 2220 2230 2240 2250 pF1KB0 YLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIEC ::::::::::::::::: NP_002 YLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIEC 2290 2300 2310 2320 2330 2340 >-- initn: 429 init1: 429 opt: 429 Z-score: 300.7 bits: 69.6 E(85289): 5.2e-10 Smith-Waterman score: 429; 100.0% identity (100.0% similar) in 58 aa overlap (2208-2265:2298-2355) 2180 2190 2200 2210 2220 2230 pF1KB0 GKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYH :::::::::::::::::::::::::::::: NP_002 GKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYH 2270 2280 2290 2300 2310 2320 2240 2250 2260 pF1KB0 QRTNTNVNCPIECFMPLDVQADREDSRE :::::::::::::::::::::::::::: NP_002 QRTNTNVNCPIECFMPLDVQADREDSRE 2330 2340 2350 2265 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 11:30:18 2016 done: Thu Nov 3 11:30:21 2016 Total Scan time: 21.930 Total Display time: 2.180 Function used was FASTA [36.3.4 Apr, 2011]