Result of FASTA (omim) for
pF1KB0009
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0009, 1654 aa
1>>>pF1KB0009 1654 - 1654 aa - 1654 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.1917+/-0.000649; mu= -2.1374+/- 0.040
mean_var=242.8392+/-48.924, 0's: 0 Z-trim(110.6): 367 B-trim: 22 in 1/54
Lambda= 0.082303
statistics sampled from 18646 (19044) to 18646 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.543), E-opt: 0.2 (0.223), width: 16
Scan time: 17.990
The best scores are: opt bits E(85289)
NP_001309918 (OMIM: 604605,608901) kalirin isoform (1654) 10922 1312.5 0
XP_011511583 (OMIM: 604605,608901) PREDICTED: kali (2977) 10767 1294.3 0
XP_016862922 (OMIM: 604605,608901) PREDICTED: kali (1656) 10752 1292.3 0
XP_006713874 (OMIM: 604605,608901) PREDICTED: kali (2979) 10597 1274.1 0
NP_001309919 (OMIM: 604605,608901) kalirin isoform (1650) 9434 1135.8 0
XP_016862923 (OMIM: 604605,608901) PREDICTED: kali (1652) 9264 1115.7 0
XP_006713875 (OMIM: 604605,608901) PREDICTED: kali (2975) 9109 1097.4 0
NP_001309921 (OMIM: 604605,608901) kalirin isoform (1613) 6223 754.6 1.6e-216
NP_003938 (OMIM: 604605,608901) kalirin isoform 2 (1663) 6223 754.6 1.7e-216
NP_001309917 (OMIM: 604605,608901) kalirin isoform (2396) 6223 754.7 2.3e-216
NP_001019831 (OMIM: 604605,608901) kalirin isoform (2986) 6223 754.7 2.7e-216
NP_001309920 (OMIM: 604605,608901) kalirin isoform (1641) 6133 743.9 2.7e-213
XP_016862924 (OMIM: 604605,608901) PREDICTED: kali (1643) 6133 743.9 2.7e-213
XP_006713878 (OMIM: 604605,608901) PREDICTED: kali (1665) 6053 734.4 2e-210
XP_016862921 (OMIM: 604605,608901) PREDICTED: kali (2366) 6053 734.5 2.7e-210
XP_011511587 (OMIM: 604605,608901) PREDICTED: kali (2367) 6053 734.5 2.7e-210
XP_016862920 (OMIM: 604605,608901) PREDICTED: kali (2398) 6053 734.5 2.7e-210
XP_011511585 (OMIM: 604605,608901) PREDICTED: kali (2401) 6053 734.5 2.7e-210
XP_016862919 (OMIM: 604605,608901) PREDICTED: kali (2955) 6053 734.5 3.2e-210
XP_006713877 (OMIM: 604605,608901) PREDICTED: kali (2956) 6053 734.5 3.2e-210
XP_016862918 (OMIM: 604605,608901) PREDICTED: kali (2968) 6053 734.5 3.2e-210
XP_011511582 (OMIM: 604605,608901) PREDICTED: kali (2987) 6053 734.5 3.2e-210
XP_011511581 (OMIM: 604605,608901) PREDICTED: kali (2987) 6053 734.5 3.2e-210
XP_006713873 (OMIM: 604605,608901) PREDICTED: kali (2988) 6053 734.5 3.2e-210
XP_006713876 (OMIM: 604605,608901) PREDICTED: kali (2966) 5978 725.6 1.5e-207
XP_016865292 (OMIM: 601893,617061) PREDICTED: trip (2612) 4993 608.6 2.2e-172
XP_016865291 (OMIM: 601893,617061) PREDICTED: trip (2880) 3786 465.3 3.4e-129
XP_016865290 (OMIM: 601893,617061) PREDICTED: trip (3093) 3786 465.4 3.6e-129
NP_009049 (OMIM: 601893,617061) triple functional (3097) 3786 465.4 3.6e-129
XP_011512411 (OMIM: 601893,617061) PREDICTED: trip (3048) 3782 464.9 4.9e-129
XP_011512410 (OMIM: 601893,617061) PREDICTED: trip (3058) 3781 464.8 5.4e-129
XP_011512409 (OMIM: 601893,617061) PREDICTED: trip (3076) 3779 464.5 6.4e-129
XP_011512412 (OMIM: 601893,617061) PREDICTED: trip (3038) 3764 462.7 2.2e-128
NP_001309930 (OMIM: 604605,608901) kalirin isoform ( 667) 744 103.8 5.3e-21
NP_001309929 (OMIM: 604605,608901) kalirin isoform ( 668) 744 103.8 5.4e-21
NP_001309928 (OMIM: 604605,608901) kalirin isoform ( 668) 744 103.8 5.4e-21
NP_001309927 (OMIM: 604605,608901) kalirin isoform ( 669) 744 103.8 5.4e-21
NP_001309926 (OMIM: 604605,608901) kalirin isoform ( 699) 744 103.8 5.6e-21
NP_001309925 (OMIM: 604605,608901) kalirin isoform ( 700) 744 103.8 5.6e-21
NP_001309924 (OMIM: 604605,608901) kalirin isoform ( 701) 744 103.8 5.6e-21
NP_001309922 (OMIM: 604605,608901) kalirin isoform (1288) 744 103.9 9.3e-21
NP_008995 (OMIM: 604605,608901) kalirin isoform 3 (1289) 744 103.9 9.3e-21
NP_891992 (OMIM: 610215) rho guanine nucleotide ex ( 580) 617 88.7 1.6e-16
NP_001104740 (OMIM: 610215) rho guanine nucleotide ( 619) 617 88.7 1.7e-16
NP_001123203 (OMIM: 609526) puratrophin-1 isoform (1110) 608 87.8 6e-16
XP_011521287 (OMIM: 609526) PREDICTED: puratrophin (1191) 608 87.8 6.3e-16
XP_011521290 (OMIM: 609526) PREDICTED: puratrophin (1191) 608 87.8 6.3e-16
XP_011521288 (OMIM: 609526) PREDICTED: puratrophin (1191) 608 87.8 6.3e-16
XP_011521289 (OMIM: 609526) PREDICTED: puratrophin (1191) 608 87.8 6.3e-16
NP_001123200 (OMIM: 609526) puratrophin-1 isoform (1191) 608 87.8 6.3e-16
>>NP_001309918 (OMIM: 604605,608901) kalirin isoform 5 [ (1654 aa)
initn: 10922 init1: 10922 opt: 10922 Z-score: 7023.4 bits: 1312.5 E(85289): 0
Smith-Waterman score: 10922; 100.0% identity (100.0% similar) in 1654 aa overlap (1-1654:1-1654)
10 20 30 40 50 60
pF1KB0 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIEKTHQSALQVQQKAEVLLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIEKTHQSALQVQQKAEVLLQA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 GHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYRRD
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 EDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSMPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSMPS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 VASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQET
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 GEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHATEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHATEI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 RKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDREVKLRDANH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDREVKLRDANH
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 EVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEHII
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 FGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLILEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLILEH
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 AGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELKDGLEVMLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELKDGLEVMLSV
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB0 PKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVFSK
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB0 EIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVLKASNIETKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVLKASNIETKQ
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB0 EWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGDGSSQPDTIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGDGSSQPDTIS
1570 1580 1590 1600 1610 1620
1630 1640 1650
pF1KB0 IASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
::::::::::::::::::::::::::::::::::
NP_001 IASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
1630 1640 1650
>>XP_011511583 (OMIM: 604605,608901) PREDICTED: kalirin (2977 aa)
initn: 10767 init1: 10767 opt: 10767 Z-score: 6920.1 bits: 1294.3 E(85289): 0
Smith-Waterman score: 10767; 100.0% identity (100.0% similar) in 1634 aa overlap (1-1634:1-1634)
10 20 30 40 50 60
pF1KB0 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIEKTHQSALQVQQKAEVLLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIEKTHQSALQVQQKAEVLLQA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 GHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYRRD
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 EDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSMPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSMPS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 VASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQET
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 GEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHATEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHATEI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 RKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDREVKLRDANH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDREVKLRDANH
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 EVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEHII
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 FGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLILEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLILEH
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 AGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELKDGLEVMLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELKDGLEVMLSV
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB0 PKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVFSK
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB0 EIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVLKASNIETKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVLKASNIETKQ
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB0 EWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGDGSSQPDTIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGDGSSQPDTIS
1570 1580 1590 1600 1610 1620
1630 1640 1650
pF1KB0 IASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
::::::::::::::
XP_011 IASRTSQNTVDSDKLSGGCELTVVLQDFSAGHSSELTIQVGQTVELLERPSERPGWCLVR
1630 1640 1650 1660 1670 1680
>--
initn: 624 init1: 215 opt: 744 Z-score: 488.2 bits: 104.1 E(85289): 1.9e-20
Smith-Waterman score: 744; 34.6% identity (66.2% similar) in 399 aa overlap (1264-1650:1912-2300)
1240 1250 1260 1270 1280 1290
pF1KB0 EDNKDLELDIIPASLSDREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHE
:.: :. : . :.. ::.:::: ::.::
XP_011 GSSYRGSLKDPAGCLNEGMAPPTPPKNPEEEQKAKALRGRMFVLNELVQTEKDYVKDLGI
1890 1900 1910 1920 1930 1940
1300 1310 1320 1330 1340 1350
pF1KB0 CLETYLWEMTSGVEE--IPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGH
.: .. . .:: .: . .:..:.::::..:::.:...:: :::: : . ...
XP_011 VVEGFMKR----IEEKGVPEDMRGKDKIVFGNIHQIYDWHKDFFLAELEKCIQEQDRLAQ
1950 1960 1970 1980 1990
1360 1370 1380 1390 1400 1410
pF1KB0 CFVTWADKFQMYVTYCKNKPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITK
:. :...:: ::.::: :. .. :. ..:.:..:. . ..:..::::.:::::
XP_011 LFIKHERKLHIYVWYCQNKPRSEYIVAEY-DAYFEEVKQEINQRLTLSDFLIKPIQRITK
2000 2010 2020 2030 2040 2050
1420 1430 1440 1450 1460
pF1KB0 YQLLLKELLTCCEEGKGELKD---GLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELIL
::::::..: :.. : .: ..:.: :::. :: :... :.::. .: .::.:.
XP_011 YQLLLKDFLRYSEKAGLECSDIEKAVELMCLVPKRCNDMMNLGRLQGFEGTLTAQGKLLQ
2060 2070 2080 2090 2100 2110
1470 1480 1490 1500 1510 1520
pF1KB0 QDAFQVWD-PKSLIRKGRERHLFLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEH
::.: : . .. . .::..:::: ..::. .. .: :..: .. . : . :.
XP_011 QDTFYVIELDAGMQSRTKERRVFLFEQIVIFSELLRKGSLTPGYMFKRSIKMNYLVLEEN
2120 2130 2140 2150 2160 2170
1530 1540 1550 1560 1570 1580
pF1KB0 VEGDPCKFALWSGRTPSSDNKTVLKASNIETKQEWIKNIREVIQERIIHLKGALKEPLQL
:..::::::: . .: ....::.:.: . .: :...: .:.. . :. ::. :..
XP_011 VDNDPCKFALMNRET---SERVVLQAANADIQQAWVQDINQVLETQRDFLN-ALQSPIEY
2180 2190 2200 2210 2220 2230
1590 1600 1610 1620 1630 1640
pF1KB0 PK---TPAKQRNNSKR---DGVEDIDSQGDGSSQPDTISIASRTSQNTVDSDKDGNLVPR
. . : .:.. : . . .: :: .: : . : ..:. .
XP_011 QRKERSTAVMRSQPARLPQASPRPYSSVPAGSEKPPKGSSYNPPLPPLKISTSNGSPGFE
2240 2250 2260 2270 2280 2290
1650
pF1KB0 WHLGPGDPFSTYV
.: ::: :
XP_011 YHQ-PGDKFEASKQNDLGGCNGTSSMAVIKDYYALKENEICVSQGEVVQVLAVNQQNMCL
2300 2310 2320 2330 2340 2350
>>XP_016862922 (OMIM: 604605,608901) PREDICTED: kalirin (1656 aa)
initn: 10752 init1: 10752 opt: 10752 Z-score: 6914.3 bits: 1292.3 E(85289): 0
Smith-Waterman score: 10752; 100.0% identity (100.0% similar) in 1632 aa overlap (23-1654:25-1656)
10 20 30 40 50
pF1KB0 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPIL
::::::::::::::::::::::::::::::::::::
XP_016 MNPPEGAAEEGGAADSDVDAFFRTGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPIL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB0 TFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB0 FPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDY
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB0 NHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB0 KAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQM
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB0 WHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFA
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB0 MNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSA
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB0 VFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKAL
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB0 LDVLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDVLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQL
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB0 CVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLL
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB0 EAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWME
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB0 DLQKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLQKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEP
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB0 SEARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYT
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB0 IEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQY
790 800 810 820 830 840
840 850 860 870 880 890
pF1KB0 ITEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAE
850 860 870 880 890 900
900 910 920 930 940 950
pF1KB0 VKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIEKTHQSALQVQQKAEVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIEKTHQSALQVQQKAEVLL
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KB0 QAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYR
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KB0 RDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSM
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KB0 PSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQ
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KB0 ETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHAT
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KB0 EIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDREVKLRDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDREVKLRDA
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KB0 NHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEH
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KB0 IIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLIL
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KB0 EHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELKDGLEVML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELKDGLEVML
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KB0 SVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVF
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KB0 SKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVLKASNIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVLKASNIET
1510 1520 1530 1540 1550 1560
1560 1570 1580 1590 1600 1610
pF1KB0 KQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGDGSSQPDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGDGSSQPDT
1570 1580 1590 1600 1610 1620
1620 1630 1640 1650
pF1KB0 ISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
::::::::::::::::::::::::::::::::::::
XP_016 ISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
1630 1640 1650
>>XP_006713874 (OMIM: 604605,608901) PREDICTED: kalirin (2979 aa)
initn: 10597 init1: 10597 opt: 10597 Z-score: 6811.0 bits: 1274.1 E(85289): 0
Smith-Waterman score: 10597; 100.0% identity (100.0% similar) in 1612 aa overlap (23-1634:25-1636)
10 20 30 40 50
pF1KB0 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPIL
::::::::::::::::::::::::::::::::::::
XP_006 MNPPEGAAEEGGAADSDVDAFFRTGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPIL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB0 TFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB0 FPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDY
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB0 NHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB0 KAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQM
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB0 WHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFA
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB0 MNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSA
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB0 VFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKAL
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB0 LDVLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDVLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQL
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB0 CVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLL
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB0 EAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWME
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB0 DLQKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLQKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEP
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB0 SEARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SEARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYT
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB0 IEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQY
790 800 810 820 830 840
840 850 860 870 880 890
pF1KB0 ITEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ITEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAE
850 860 870 880 890 900
900 910 920 930 940 950
pF1KB0 VKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIEKTHQSALQVQQKAEVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIEKTHQSALQVQQKAEVLL
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KB0 QAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYR
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KB0 RDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSM
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KB0 PSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQ
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KB0 ETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHAT
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KB0 EIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDREVKLRDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDREVKLRDA
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KB0 NHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEH
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KB0 IIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLIL
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KB0 EHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELKDGLEVML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELKDGLEVML
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KB0 SVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVF
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KB0 SKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVLKASNIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVLKASNIET
1510 1520 1530 1540 1550 1560
1560 1570 1580 1590 1600 1610
pF1KB0 KQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGDGSSQPDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGDGSSQPDT
1570 1580 1590 1600 1610 1620
1620 1630 1640 1650
pF1KB0 ISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
::::::::::::::::
XP_006 ISIASRTSQNTVDSDKLSGGCELTVVLQDFSAGHSSELTIQVGQTVELLERPSERPGWCL
1630 1640 1650 1660 1670 1680
>--
initn: 624 init1: 215 opt: 744 Z-score: 488.2 bits: 104.1 E(85289): 1.9e-20
Smith-Waterman score: 744; 34.6% identity (66.2% similar) in 399 aa overlap (1264-1650:1914-2302)
1240 1250 1260 1270 1280 1290
pF1KB0 EDNKDLELDIIPASLSDREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHE
:.: :. : . :.. ::.:::: ::.::
XP_006 GSSYRGSLKDPAGCLNEGMAPPTPPKNPEEEQKAKALRGRMFVLNELVQTEKDYVKDLGI
1890 1900 1910 1920 1930 1940
1300 1310 1320 1330 1340 1350
pF1KB0 CLETYLWEMTSGVEE--IPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGH
.: .. . .:: .: . .:..:.::::..:::.:...:: :::: : . ...
XP_006 VVEGFMKR----IEEKGVPEDMRGKDKIVFGNIHQIYDWHKDFFLAELEKCIQEQDRLAQ
1950 1960 1970 1980 1990
1360 1370 1380 1390 1400 1410
pF1KB0 CFVTWADKFQMYVTYCKNKPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITK
:. :...:: ::.::: :. .. :. ..:.:..:. . ..:..::::.:::::
XP_006 LFIKHERKLHIYVWYCQNKPRSEYIVAEY-DAYFEEVKQEINQRLTLSDFLIKPIQRITK
2000 2010 2020 2030 2040 2050
1420 1430 1440 1450 1460
pF1KB0 YQLLLKELLTCCEEGKGELKD---GLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELIL
::::::..: :.. : .: ..:.: :::. :: :... :.::. .: .::.:.
XP_006 YQLLLKDFLRYSEKAGLECSDIEKAVELMCLVPKRCNDMMNLGRLQGFEGTLTAQGKLLQ
2060 2070 2080 2090 2100 2110
1470 1480 1490 1500 1510 1520
pF1KB0 QDAFQVWD-PKSLIRKGRERHLFLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEH
::.: : . .. . .::..:::: ..::. .. .: :..: .. . : . :.
XP_006 QDTFYVIELDAGMQSRTKERRVFLFEQIVIFSELLRKGSLTPGYMFKRSIKMNYLVLEEN
2120 2130 2140 2150 2160 2170
1530 1540 1550 1560 1570 1580
pF1KB0 VEGDPCKFALWSGRTPSSDNKTVLKASNIETKQEWIKNIREVIQERIIHLKGALKEPLQL
:..::::::: . .: ....::.:.: . .: :...: .:.. . :. ::. :..
XP_006 VDNDPCKFALMNRET---SERVVLQAANADIQQAWVQDINQVLETQRDFLN-ALQSPIEY
2180 2190 2200 2210 2220 2230
1590 1600 1610 1620 1630 1640
pF1KB0 PK---TPAKQRNNSKR---DGVEDIDSQGDGSSQPDTISIASRTSQNTVDSDKDGNLVPR
. . : .:.. : . . .: :: .: : . : ..:. .
XP_006 QRKERSTAVMRSQPARLPQASPRPYSSVPAGSEKPPKGSSYNPPLPPLKISTSNGSPGFE
2240 2250 2260 2270 2280 2290
1650
pF1KB0 WHLGPGDPFSTYV
.: ::: :
XP_006 YHQ-PGDKFEASKQNDLGGCNGTSSMAVIKDYYALKENEICVSQGEVVQVLAVNQQNMCL
2300 2310 2320 2330 2340 2350
>>NP_001309919 (OMIM: 604605,608901) kalirin isoform 6 [ (1650 aa)
initn: 9433 init1: 4725 opt: 9434 Z-score: 6068.5 bits: 1135.8 E(85289): 0
Smith-Waterman score: 10771; 98.7% identity (98.7% similar) in 1663 aa overlap (1-1654:1-1650)
10 20 30 40 50 60
pF1KB0 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSE
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLR-----------
670 680 690 700
730 740 750 760 770 780
pF1KB0 ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --DSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
710 720 730 740 750 760
790 800 810 820 830 840
pF1KB0 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
770 780 790 800 810 820
850 860 870 880 890 900
pF1KB0 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
830 840 850 860 870 880
910 920 930 940 950
pF1KB0 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIE---------KTHQSALQVQ
::::::::::::::::::::::::::::::::::::::::: ::::::::::
NP_001 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIESLFHATSLQKTHQSALQVQ
890 900 910 920 930 940
960 970 980 990 1000 1010
pF1KB0 QKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLE
950 960 970 980 990 1000
1020 1030 1040 1050 1060 1070
pF1KB0 SLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYI
1010 1020 1030 1040 1050 1060
1080 1090 1100 1110 1120 1130
pF1KB0 HRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAK
1070 1080 1090 1100 1110 1120
1140 1150 1160 1170 1180 1190
pF1KB0 QALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVE
1130 1140 1150 1160 1170 1180
1200 1210 1220 1230 1240 1250
pF1KB0 KGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDR
1190 1200 1210 1220 1230 1240
1260 1270 1280 1290 1300 1310
pF1KB0 EVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPP
1250 1260 1270 1280 1290 1300
1320 1330 1340 1350 1360 1370
pF1KB0 GILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKP
1310 1320 1330 1340 1350 1360
1380 1390 1400 1410 1420 1430
pF1KB0 DSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELK
1370 1380 1390 1400 1410 1420
1440 1450 1460 1470 1480 1490
pF1KB0 DGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFL
1430 1440 1450 1460 1470 1480
1500 1510 1520 1530 1540 1550
pF1KB0 FEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVL
1490 1500 1510 1520 1530 1540
1560 1570 1580 1590 1600 1610
pF1KB0 KASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGD
1550 1560 1570 1580 1590 1600
1620 1630 1640 1650
pF1KB0 GSSQPDTISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
:::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSQPDTISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
1610 1620 1630 1640 1650
>>XP_016862923 (OMIM: 604605,608901) PREDICTED: kalirin (1652 aa)
initn: 9263 init1: 4725 opt: 9264 Z-score: 5959.4 bits: 1115.7 E(85289): 0
Smith-Waterman score: 10601; 98.7% identity (98.7% similar) in 1641 aa overlap (23-1654:25-1652)
10 20 30 40 50
pF1KB0 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPIL
::::::::::::::::::::::::::::::::::::
XP_016 MNPPEGAAEEGGAADSDVDAFFRTGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPIL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB0 TFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB0 FPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDY
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB0 NHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB0 KAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQM
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB0 WHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFA
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB0 MNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSA
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB0 VFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKAL
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB0 LDVLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDVLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQL
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB0 CVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLL
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB0 EAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWME
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB0 DLQKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEP
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLQKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLR---------
670 680 690 700 710
720 730 740 750 760 770
pF1KB0 SEARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ----DSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYT
720 730 740 750 760
780 790 800 810 820 830
pF1KB0 IEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQY
770 780 790 800 810 820
840 850 860 870 880 890
pF1KB0 ITEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAE
830 840 850 860 870 880
900 910 920 930 940
pF1KB0 VKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIE---------KTHQSALQ
::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_016 VKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIESLFHATSLQKTHQSALQ
890 900 910 920 930 940
950 960 970 980 990 1000
pF1KB0 VQQKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQQKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSV
950 960 970 980 990 1000
1010 1020 1030 1040 1050 1060
pF1KB0 LESLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LESLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLK
1010 1020 1030 1040 1050 1060
1070 1080 1090 1100 1110 1120
pF1KB0 YIHRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIHRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERS
1070 1080 1090 1100 1110 1120
1130 1140 1150 1160 1170 1180
pF1KB0 AKQALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKQALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSF
1130 1140 1150 1160 1170 1180
1190 1200 1210 1220 1230 1240
pF1KB0 VEKGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEKGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLS
1190 1200 1210 1220 1230 1240
1250 1260 1270 1280 1290 1300
pF1KB0 DREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEI
1250 1260 1270 1280 1290 1300
1310 1320 1330 1340 1350 1360
pF1KB0 PPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKN
1310 1320 1330 1340 1350 1360
1370 1380 1390 1400 1410 1420
pF1KB0 KPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGE
1370 1380 1390 1400 1410 1420
1430 1440 1450 1460 1470 1480
pF1KB0 LKDGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKDGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHL
1430 1440 1450 1460 1470 1480
1490 1500 1510 1520 1530 1540
pF1KB0 FLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKT
1490 1500 1510 1520 1530 1540
1550 1560 1570 1580 1590 1600
pF1KB0 VLKASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLKASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQ
1550 1560 1570 1580 1590 1600
1610 1620 1630 1640 1650
pF1KB0 GDGSSQPDTISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDGSSQPDTISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
1610 1620 1630 1640 1650
>>XP_006713875 (OMIM: 604605,608901) PREDICTED: kalirin (2975 aa)
initn: 9108 init1: 4570 opt: 9109 Z-score: 5856.1 bits: 1097.4 E(85289): 0
Smith-Waterman score: 10446; 98.6% identity (98.6% similar) in 1621 aa overlap (23-1634:25-1632)
10 20 30 40 50
pF1KB0 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPIL
::::::::::::::::::::::::::::::::::::
XP_006 MNPPEGAAEEGGAADSDVDAFFRTGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPIL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB0 TFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB0 FPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDY
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB0 NHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB0 KAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQM
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB0 WHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFA
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB0 MNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSA
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB0 VFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKAL
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB0 LDVLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDVLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQL
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB0 CVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLL
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB0 EAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWME
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB0 DLQKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEP
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLQKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLR---------
670 680 690 700 710
720 730 740 750 760 770
pF1KB0 SEARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ----DSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYT
720 730 740 750 760
780 790 800 810 820 830
pF1KB0 IEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQY
770 780 790 800 810 820
840 850 860 870 880 890
pF1KB0 ITEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ITEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAE
830 840 850 860 870 880
900 910 920 930 940
pF1KB0 VKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIE---------KTHQSALQ
::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_006 VKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIESLFHATSLQKTHQSALQ
890 900 910 920 930 940
950 960 970 980 990 1000
pF1KB0 VQQKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VQQKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSV
950 960 970 980 990 1000
1010 1020 1030 1040 1050 1060
pF1KB0 LESLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LESLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLK
1010 1020 1030 1040 1050 1060
1070 1080 1090 1100 1110 1120
pF1KB0 YIHRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YIHRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERS
1070 1080 1090 1100 1110 1120
1130 1140 1150 1160 1170 1180
pF1KB0 AKQALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AKQALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSF
1130 1140 1150 1160 1170 1180
1190 1200 1210 1220 1230 1240
pF1KB0 VEKGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VEKGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLS
1190 1200 1210 1220 1230 1240
1250 1260 1270 1280 1290 1300
pF1KB0 DREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEI
1250 1260 1270 1280 1290 1300
1310 1320 1330 1340 1350 1360
pF1KB0 PPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKN
1310 1320 1330 1340 1350 1360
1370 1380 1390 1400 1410 1420
pF1KB0 KPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGE
1370 1380 1390 1400 1410 1420
1430 1440 1450 1460 1470 1480
pF1KB0 LKDGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKDGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHL
1430 1440 1450 1460 1470 1480
1490 1500 1510 1520 1530 1540
pF1KB0 FLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKT
1490 1500 1510 1520 1530 1540
1550 1560 1570 1580 1590 1600
pF1KB0 VLKASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLKASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQ
1550 1560 1570 1580 1590 1600
1610 1620 1630 1640 1650
pF1KB0 GDGSSQPDTISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
:::::::::::::::::::::::::
XP_006 GDGSSQPDTISIASRTSQNTVDSDKLSGGCELTVVLQDFSAGHSSELTIQVGQTVELLER
1610 1620 1630 1640 1650 1660
>--
initn: 624 init1: 215 opt: 744 Z-score: 488.2 bits: 104.1 E(85289): 1.9e-20
Smith-Waterman score: 744; 34.6% identity (66.2% similar) in 399 aa overlap (1264-1650:1910-2298)
1240 1250 1260 1270 1280 1290
pF1KB0 EDNKDLELDIIPASLSDREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHE
:.: :. : . :.. ::.:::: ::.::
XP_006 GSSYRGSLKDPAGCLNEGMAPPTPPKNPEEEQKAKALRGRMFVLNELVQTEKDYVKDLGI
1880 1890 1900 1910 1920 1930
1300 1310 1320 1330 1340 1350
pF1KB0 CLETYLWEMTSGVEE--IPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGH
.: .. . .:: .: . .:..:.::::..:::.:...:: :::: : . ...
XP_006 VVEGFMKR----IEEKGVPEDMRGKDKIVFGNIHQIYDWHKDFFLAELEKCIQEQDRLAQ
1940 1950 1960 1970 1980 1990
1360 1370 1380 1390 1400 1410
pF1KB0 CFVTWADKFQMYVTYCKNKPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITK
:. :...:: ::.::: :. .. :. ..:.:..:. . ..:..::::.:::::
XP_006 LFIKHERKLHIYVWYCQNKPRSEYIVAEY-DAYFEEVKQEINQRLTLSDFLIKPIQRITK
2000 2010 2020 2030 2040 2050
1420 1430 1440 1450 1460
pF1KB0 YQLLLKELLTCCEEGKGELKD---GLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELIL
::::::..: :.. : .: ..:.: :::. :: :... :.::. .: .::.:.
XP_006 YQLLLKDFLRYSEKAGLECSDIEKAVELMCLVPKRCNDMMNLGRLQGFEGTLTAQGKLLQ
2060 2070 2080 2090 2100 2110
1470 1480 1490 1500 1510 1520
pF1KB0 QDAFQVWD-PKSLIRKGRERHLFLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEH
::.: : . .. . .::..:::: ..::. .. .: :..: .. . : . :.
XP_006 QDTFYVIELDAGMQSRTKERRVFLFEQIVIFSELLRKGSLTPGYMFKRSIKMNYLVLEEN
2120 2130 2140 2150 2160 2170
1530 1540 1550 1560 1570 1580
pF1KB0 VEGDPCKFALWSGRTPSSDNKTVLKASNIETKQEWIKNIREVIQERIIHLKGALKEPLQL
:..::::::: . .: ....::.:.: . .: :...: .:.. . :. ::. :..
XP_006 VDNDPCKFALMNRET---SERVVLQAANADIQQAWVQDINQVLETQRDFLN-ALQSPIEY
2180 2190 2200 2210 2220 2230
1590 1600 1610 1620 1630 1640
pF1KB0 PK---TPAKQRNNSKR---DGVEDIDSQGDGSSQPDTISIASRTSQNTVDSDKDGNLVPR
. . : .:.. : . . .: :: .: : . : ..:. .
XP_006 QRKERSTAVMRSQPARLPQASPRPYSSVPAGSEKPPKGSSYNPPLPPLKISTSNGSPGFE
2240 2250 2260 2270 2280 2290
1650
pF1KB0 WHLGPGDPFSTYV
.: ::: :
XP_006 YHQ-PGDKFEASKQNDLGGCNGTSSMAVIKDYYALKENEICVSQGEVVQVLAVNQQNMCL
2300 2310 2320 2330 2340
>>NP_001309921 (OMIM: 604605,608901) kalirin isoform 8 [ (1613 aa)
initn: 10155 init1: 6206 opt: 6223 Z-score: 4008.1 bits: 754.6 E(85289): 1.6e-216
Smith-Waterman score: 10440; 96.5% identity (96.5% similar) in 1663 aa overlap (1-1654:1-1613)
10 20 30 40 50 60
pF1KB0 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
850 860 870 880 890 900
910 920 930 940 950
pF1KB0 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIE---------KTHQSALQVQ
::::::::::::::::::::::::::::::::::::::::: ::::::::::
NP_001 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIESLFHATSLQKTHQSALQVQ
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KB0 QKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQ------
970 980 990 1000 1010
1020 1030 1040 1050 1060 1070
pF1KB0 SLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYI
::::::::::::::::
NP_001 --------------------------------------------ACTLARRNAEVFLKYI
1020 1030
1080 1090 1100 1110 1120 1130
pF1KB0 HRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAK
1040 1050 1060 1070 1080 1090
1140 1150 1160 1170 1180 1190
pF1KB0 QALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVE
1100 1110 1120 1130 1140 1150
1200 1210 1220 1230 1240 1250
pF1KB0 KGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDR
1160 1170 1180 1190 1200 1210
1260 1270 1280 1290 1300 1310
pF1KB0 EVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPP
1220 1230 1240 1250 1260 1270
1320 1330 1340 1350 1360 1370
pF1KB0 GILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKP
1280 1290 1300 1310 1320 1330
1380 1390 1400 1410 1420 1430
pF1KB0 DSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELK
1340 1350 1360 1370 1380 1390
1440 1450 1460 1470 1480 1490
pF1KB0 DGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFL
1400 1410 1420 1430 1440 1450
1500 1510 1520 1530 1540 1550
pF1KB0 FEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVL
1460 1470 1480 1490 1500 1510
1560 1570 1580 1590 1600 1610
pF1KB0 KASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGD
1520 1530 1540 1550 1560 1570
1620 1630 1640 1650
pF1KB0 GSSQPDTISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
:::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSQPDTISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
1580 1590 1600 1610
>>NP_003938 (OMIM: 604605,608901) kalirin isoform 2 [Hom (1663 aa)
initn: 6206 init1: 6206 opt: 6223 Z-score: 4007.9 bits: 754.6 E(85289): 1.7e-216
Smith-Waterman score: 10894; 99.5% identity (99.5% similar) in 1663 aa overlap (1-1654:1-1663)
10 20 30 40 50 60
pF1KB0 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
850 860 870 880 890 900
910 920 930 940 950
pF1KB0 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIE---------KTHQSALQVQ
::::::::::::::::::::::::::::::::::::::::: ::::::::::
NP_003 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIESLFHATSLQKTHQSALQVQ
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KB0 QKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLE
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KB0 SLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYI
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KB0 HRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAK
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KB0 QALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVE
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KB0 KGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDR
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KB0 EVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPP
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KB0 GILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKP
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KB0 DSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELK
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KB0 DGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFL
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KB0 FEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVL
1510 1520 1530 1540 1550 1560
1560 1570 1580 1590 1600 1610
pF1KB0 KASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGD
1570 1580 1590 1600 1610 1620
1620 1630 1640 1650
pF1KB0 GSSQPDTISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
:::::::::::::::::::::::::::::::::::::::::::
NP_003 GSSQPDTISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
1630 1640 1650 1660
>>NP_001309917 (OMIM: 604605,608901) kalirin isoform 4 [ (2396 aa)
initn: 6621 init1: 6206 opt: 6223 Z-score: 4005.5 bits: 754.7 E(85289): 2.3e-216
Smith-Waterman score: 10739; 99.5% identity (99.5% similar) in 1643 aa overlap (1-1634:1-1643)
10 20 30 40 50 60
pF1KB0 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
850 860 870 880 890 900
910 920 930 940 950
pF1KB0 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIE---------KTHQSALQVQ
::::::::::::::::::::::::::::::::::::::::: ::::::::::
NP_001 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIESLFHATSLQKTHQSALQVQ
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KB0 QKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLE
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KB0 SLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYI
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KB0 HRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAK
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KB0 QALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVE
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KB0 KGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDR
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KB0 EVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPP
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KB0 GILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKP
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KB0 DSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELK
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KB0 DGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFL
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KB0 FEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVL
1510 1520 1530 1540 1550 1560
1560 1570 1580 1590 1600 1610
pF1KB0 KASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGD
1570 1580 1590 1600 1610 1620
1620 1630 1640 1650
pF1KB0 GSSQPDTISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
:::::::::::::::::::::::
NP_001 GSSQPDTISIASRTSQNTVDSDKLSGGCELTVVLQDFSAGHSSELTIQVGQTVELLERPS
1630 1640 1650 1660 1670 1680
>--
initn: 644 init1: 215 opt: 744 Z-score: 489.6 bits: 104.1 E(85289): 1.6e-20
Smith-Waterman score: 744; 34.6% identity (66.2% similar) in 399 aa overlap (1264-1650:1920-2308)
1240 1250 1260 1270 1280 1290
pF1KB0 EDNKDLELDIIPASLSDREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHE
:.: :. : . :.. ::.:::: ::.::
NP_001 GSSYRGSLKDPAGCLNEGMAPPTPPKNPEEEQKAKALRGRMFVLNELVQTEKDYVKDLGI
1890 1900 1910 1920 1930 1940
1300 1310 1320 1330 1340 1350
pF1KB0 CLETYLWEMTSGVEE--IPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGH
.: .. . .:: .: . .:..:.::::..:::.:...:: :::: : . ...
NP_001 VVEGFMKR----IEEKGVPEDMRGKDKIVFGNIHQIYDWHKDFFLAELEKCIQEQDRLAQ
1950 1960 1970 1980 1990 2000
1360 1370 1380 1390 1400 1410
pF1KB0 CFVTWADKFQMYVTYCKNKPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITK
:. :...:: ::.::: :. .. :. ..:.:..:. . ..:..::::.:::::
NP_001 LFIKHERKLHIYVWYCQNKPRSEYIVAEY-DAYFEEVKQEINQRLTLSDFLIKPIQRITK
2010 2020 2030 2040 2050 2060
1420 1430 1440 1450 1460
pF1KB0 YQLLLKELLTCCEEGKGELKD---GLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELIL
::::::..: :.. : .: ..:.: :::. :: :... :.::. .: .::.:.
NP_001 YQLLLKDFLRYSEKAGLECSDIEKAVELMCLVPKRCNDMMNLGRLQGFEGTLTAQGKLLQ
2070 2080 2090 2100 2110 2120
1470 1480 1490 1500 1510 1520
pF1KB0 QDAFQVWD-PKSLIRKGRERHLFLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEH
::.: : . .. . .::..:::: ..::. .. .: :..: .. . : . :.
NP_001 QDTFYVIELDAGMQSRTKERRVFLFEQIVIFSELLRKGSLTPGYMFKRSIKMNYLVLEEN
2130 2140 2150 2160 2170 2180
1530 1540 1550 1560 1570 1580
pF1KB0 VEGDPCKFALWSGRTPSSDNKTVLKASNIETKQEWIKNIREVIQERIIHLKGALKEPLQL
:..::::::: . .: ....::.:.: . .: :...: .:.. . :. ::. :..
NP_001 VDNDPCKFALMNRET---SERVVLQAANADIQQAWVQDINQVLETQRDFLN-ALQSPIEY
2190 2200 2210 2220 2230 2240
1590 1600 1610 1620 1630 1640
pF1KB0 PK---TPAKQRNNSKR---DGVEDIDSQGDGSSQPDTISIASRTSQNTVDSDKDGNLVPR
. . : .:.. : . . .: :: .: : . : ..:. .
NP_001 QRKERSTAVMRSQPARLPQASPRPYSSVPAGSEKPPKGSSYNPPLPPLKISTSNGSPGFE
2250 2260 2270 2280 2290 2300
1650
pF1KB0 WHLGPGDPFSTYV
.: ::: :
NP_001 YHQ-PGDKFEASKNDLGGCNGTSSMAVIKDYYALKENEICVSQGEVVQVLAVNQQNMCLV
2310 2320 2330 2340 2350
1654 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 22:31:05 2016 done: Wed Nov 2 22:31:08 2016
Total Scan time: 17.990 Total Display time: 1.300
Function used was FASTA [36.3.4 Apr, 2011]