FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0020, 1783 aa 1>>>pF1KB0020 1783 - 1783 aa - 1783 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.5606+/-0.000456; mu= 0.1036+/- 0.029 mean_var=297.0188+/-58.299, 0's: 0 Z-trim(119.1): 62 B-trim: 60 in 1/55 Lambda= 0.074419 statistics sampled from 32649 (32716) to 32649 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.692), E-opt: 0.2 (0.384), width: 16 Scan time: 18.700 The best scores are: opt bits E(85289) NP_005091 (OMIM: 604698) A-kinase anchor protein 1 (1782) 11297 1228.2 0 XP_016867006 (OMIM: 604698) PREDICTED: A-kinase an (1782) 11297 1228.2 0 NP_653080 (OMIM: 604698) A-kinase anchor protein 1 (1684) 10617 1155.2 0 XP_005267292 (OMIM: 604698) PREDICTED: A-kinase an (1677) 10614 1154.9 0 XP_016867007 (OMIM: 604698) PREDICTED: A-kinase an (1659) 10509 1143.6 0 NP_849188 (OMIM: 608581,613587) retinitis pigmento (2400) 311 48.8 0.00075 >>NP_005091 (OMIM: 604698) A-kinase anchor protein 12 is (1782 aa) initn: 9753 init1: 9753 opt: 11297 Z-score: 6566.5 bits: 1228.2 E(85289): 0 Smith-Waterman score: 11297; 99.7% identity (99.9% similar) in 1783 aa overlap (1-1783:1-1782) 10 20 30 40 50 60 pF1KB0 MGAGSSTEQRSPEQPPEGSSTPAEPEPSGGGPSAEAAPDTTADPAIAASDPATKLLQKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MGAGSSTEQRSPEQPPEGSSTPAEPEPSGGGPSAEAAPDTTADPAIAASDPATKLLQKNG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 QLSTINGVAEQDELSLQEGDLNGQKGALNGQGALNSQEEEEVIVTEVGQRDSEDVSERDS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::: NP_005 QLSTINGVAEQDELSLQEGDLNGQKGALNGQGALNSQEEEEVIVTEVGQRDSEDVSKRDS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 DKEMATKSAVVHDITDDGQEETPEIIEQIPSSESNLEELTQPTESQANDIGFKKVFKFVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 DKEMATKSAVVHDITDDGQEETPEIIEQIPSSESNLEELTQPTESQANDIGFKKVFKFVG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 FKFTVKKDKTEKPDTVQLLTVKKDEGEGAAGAGDHQDPSLGAGEAASKESEPKQSTEKPE :::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::: NP_005 FKFTVKKDKTEKPDTVQLLTVKKDEGEGAAGAGDHKDPSLGAGEAASKESEPKQSTEKPE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 ETLKREQSHAEISPPAESGQAVEECKEEGEEKQEKEPSKSAESPTSPVTSETGSTFKKFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ETLKREQSHAEISPPAESGQAVEECKEEGEEKQEKEPSKSAESPTSPVTSETGSTFKKFF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 TQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPEKVDTEEDGKAEVASEKLTASEQAHPQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPEKVDTEEDGKAEVASEKLTASEQAHPQE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 PAESAHEPRLSAEYEKVELPSEEQVSGSQGPSEEKPAPLATEVFDEKIEVHQEEVVAEVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PAESAHEPRLSAEYEKVELPSEEQVSGSQGPSEEKPAPLATEVFDEKIEVHQEEVVAEVH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 VSIVEERTEEQKTEVEETAGSVPAEELVEMDAEPQEAEPAKELVKLKETCVSGEDPTQGA :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VSTVEERTEEQKTEVEETAGSVPAEELVEMDAEPQEAEPAKELVKLKETCVSGEDPTQGA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 DLSPDEKVLSKPPEGVVSEVEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 DLSPDEKVLSKPPEGVVSEVEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 DEESGEHTQVPADSPDSQEEQKGESSASSPEEPEEITCLEKGLAEVQQDGEAEEGATSDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 DEESGEHTQVPADSPDSQEEQKGESSASSPEEPEEITCLEKGLAEVQQDGEAEEGATSDG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 EKKREGVTPWASFKKMVTPKKRVRRPSESDKEDELDKVKSATLSSTESTASEMQEEMKGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 EKKREGVTPWASFKKMVTPKKRVRRPSESDKEDELDKVKSATLSSTESTASEMQEEMKGS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 VEEPKPEEPKRKVDTSVSWEALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VEEPKPEEPKRKVDTSVSWEALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 KETGTDGILAGSQEHDPGQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KETGTDGILAGSQEHDPGQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 EDSIAGSGVEHSTPDTEPGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 EDSIAGSGVEHSTPDTEPGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 SDVPAVVPLSEYDAVEREKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SDVPAVVPLSEYDAVEREKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 RAATIIEERSPSWISASVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RAATIIEERSPSWISASVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 RGDTVVSEAELTPEAVTAAETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RGDTVVSEAELTPEAVTAAETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEAT 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 PVQEVEGGVPDIEEQERRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PVQEVEGGVPDIEEQERRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQ 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 AEASGLKKETDVVLKVDAQEAKTEPFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 AEASGLKKETDVVLKVDAQEAKTEPFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 AETLAGVKSQEMVMEQAIPPDSVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 AETLAGVKSQEMVMEQAIPPDSVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEV 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 ASGTQSGGTEAEAVPAQKERPPAPSSFVFQEETKEQSKMEDTLEHTDKEVSVETVSILSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ASGTQSGGTEAEAVPAQKERPPAPSSFVFQEETKEQSKMEDTLEHTDKEVSVETVSILSK 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 TEGTQEADQYADEKTKDVPFFEGLEGSIDTGITVSREKVTEVALKGEGTEEAECKKDDAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TEGTQEADQYADEKTKDVPFFEGLEGSIDTGITVSREKVTEVALKGEGTEEAECKKDDAL 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 ELQSHAKSPPSPVEREMVVQVEREKTEAEPTHVNEEKLEHETAVTVSEEVSKQLLQTVNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ELQSHAKSPPSPVEREMVVQVEREKTEAEPTHVNEEKLEHETAVTVSEEVSKQLLQTVNV 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 PIIDGAKEVSSLEGSPPPCLGQEEAVCTKIQVQSSEASFTLTAAAEEEKVLGETANILET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PIIDGAKEVSSLEGSPPPCLGQEEAVCTKIQVQSSEASFTLTAAAEEEKVLGETANILET 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 GETLEPAGAHLVLEEKSSEKNEDFAAHPGEDAVPTGPDCQAKSTPVIVSATTKKGLSSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GETLEPAGAHLVLEEKSSEKNEDFAAHPGEDAVPTGPDCQAKSTPVIVSATTKKGLSSDL 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 EGEKTTSLKWKSDEVDEQVACQEVKVSVAIEEDLEPENGILELETKSSKLVQNIIQTAVD ::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::: NP_005 EGEKTTSLKWKSDEVDEQVACQEVKVSVAIE-DLEPENGILELETKSSKLVQNIIQTAVD 1510 1520 1530 1540 1550 1570 1580 1590 1600 1610 1620 pF1KB0 QFVRTEETATEMLTSELQTQAHVIKADSQDAGQETEKEGEDPQASAQDETPITSAKEESE ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: NP_005 QFVRTEETATEMLTSELQTQAHVIKADSQDAGQETEKEGEEPQASAQDETPITSAKEESE 1560 1570 1580 1590 1600 1610 1630 1640 1650 1660 1670 1680 pF1KB0 STAVGQAHSDISKDMSEASEKTMTVEVEGSTVNDQQLEEVVLPSEEEGGGAGTKSVPEDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 STAVGQAHSDISKDMSEASEKTMTVEVEGSTVNDQQLEEVVLPSEEEGGGAGTKSVPEDD 1620 1630 1640 1650 1660 1670 1690 1700 1710 1720 1730 1740 pF1KB0 GHALLAERIEKSLVEPKEDEKGDDVDDPENQNSALADTDASGGLTKESPDTNGPKQKEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GHALLAERIEKSLVEPKEDEKGDDVDDPENQNSALADTDASGGLTKESPDTNGPKQKEKE 1680 1690 1700 1710 1720 1730 1750 1760 1770 1780 pF1KB0 DAQEVELQEGKVHSESDKAITPQAQEELQKQERESAKSELTES ::::::::::::::::::::::::::::::::::::::::::: NP_005 DAQEVELQEGKVHSESDKAITPQAQEELQKQERESAKSELTES 1740 1750 1760 1770 1780 >>XP_016867006 (OMIM: 604698) PREDICTED: A-kinase anchor (1782 aa) initn: 9753 init1: 9753 opt: 11297 Z-score: 6566.5 bits: 1228.2 E(85289): 0 Smith-Waterman score: 11297; 99.7% identity (99.9% similar) in 1783 aa overlap (1-1783:1-1782) 10 20 30 40 50 60 pF1KB0 MGAGSSTEQRSPEQPPEGSSTPAEPEPSGGGPSAEAAPDTTADPAIAASDPATKLLQKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGAGSSTEQRSPEQPPEGSSTPAEPEPSGGGPSAEAAPDTTADPAIAASDPATKLLQKNG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 QLSTINGVAEQDELSLQEGDLNGQKGALNGQGALNSQEEEEVIVTEVGQRDSEDVSERDS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::: XP_016 QLSTINGVAEQDELSLQEGDLNGQKGALNGQGALNSQEEEEVIVTEVGQRDSEDVSKRDS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 DKEMATKSAVVHDITDDGQEETPEIIEQIPSSESNLEELTQPTESQANDIGFKKVFKFVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DKEMATKSAVVHDITDDGQEETPEIIEQIPSSESNLEELTQPTESQANDIGFKKVFKFVG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 FKFTVKKDKTEKPDTVQLLTVKKDEGEGAAGAGDHQDPSLGAGEAASKESEPKQSTEKPE :::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::: XP_016 FKFTVKKDKTEKPDTVQLLTVKKDEGEGAAGAGDHKDPSLGAGEAASKESEPKQSTEKPE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 ETLKREQSHAEISPPAESGQAVEECKEEGEEKQEKEPSKSAESPTSPVTSETGSTFKKFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETLKREQSHAEISPPAESGQAVEECKEEGEEKQEKEPSKSAESPTSPVTSETGSTFKKFF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 TQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPEKVDTEEDGKAEVASEKLTASEQAHPQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPEKVDTEEDGKAEVASEKLTASEQAHPQE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 PAESAHEPRLSAEYEKVELPSEEQVSGSQGPSEEKPAPLATEVFDEKIEVHQEEVVAEVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAESAHEPRLSAEYEKVELPSEEQVSGSQGPSEEKPAPLATEVFDEKIEVHQEEVVAEVH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 VSIVEERTEEQKTEVEETAGSVPAEELVEMDAEPQEAEPAKELVKLKETCVSGEDPTQGA :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSTVEERTEEQKTEVEETAGSVPAEELVEMDAEPQEAEPAKELVKLKETCVSGEDPTQGA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 DLSPDEKVLSKPPEGVVSEVEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLSPDEKVLSKPPEGVVSEVEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 DEESGEHTQVPADSPDSQEEQKGESSASSPEEPEEITCLEKGLAEVQQDGEAEEGATSDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEESGEHTQVPADSPDSQEEQKGESSASSPEEPEEITCLEKGLAEVQQDGEAEEGATSDG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 EKKREGVTPWASFKKMVTPKKRVRRPSESDKEDELDKVKSATLSSTESTASEMQEEMKGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKKREGVTPWASFKKMVTPKKRVRRPSESDKEDELDKVKSATLSSTESTASEMQEEMKGS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 VEEPKPEEPKRKVDTSVSWEALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEEPKPEEPKRKVDTSVSWEALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 KETGTDGILAGSQEHDPGQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KETGTDGILAGSQEHDPGQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 EDSIAGSGVEHSTPDTEPGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDSIAGSGVEHSTPDTEPGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 SDVPAVVPLSEYDAVEREKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDVPAVVPLSEYDAVEREKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 RAATIIEERSPSWISASVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAATIIEERSPSWISASVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 RGDTVVSEAELTPEAVTAAETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGDTVVSEAELTPEAVTAAETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEAT 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 PVQEVEGGVPDIEEQERRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVQEVEGGVPDIEEQERRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQ 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 AEASGLKKETDVVLKVDAQEAKTEPFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEASGLKKETDVVLKVDAQEAKTEPFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 AETLAGVKSQEMVMEQAIPPDSVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AETLAGVKSQEMVMEQAIPPDSVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEV 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 ASGTQSGGTEAEAVPAQKERPPAPSSFVFQEETKEQSKMEDTLEHTDKEVSVETVSILSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASGTQSGGTEAEAVPAQKERPPAPSSFVFQEETKEQSKMEDTLEHTDKEVSVETVSILSK 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 TEGTQEADQYADEKTKDVPFFEGLEGSIDTGITVSREKVTEVALKGEGTEEAECKKDDAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEGTQEADQYADEKTKDVPFFEGLEGSIDTGITVSREKVTEVALKGEGTEEAECKKDDAL 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 ELQSHAKSPPSPVEREMVVQVEREKTEAEPTHVNEEKLEHETAVTVSEEVSKQLLQTVNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELQSHAKSPPSPVEREMVVQVEREKTEAEPTHVNEEKLEHETAVTVSEEVSKQLLQTVNV 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 PIIDGAKEVSSLEGSPPPCLGQEEAVCTKIQVQSSEASFTLTAAAEEEKVLGETANILET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIIDGAKEVSSLEGSPPPCLGQEEAVCTKIQVQSSEASFTLTAAAEEEKVLGETANILET 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 GETLEPAGAHLVLEEKSSEKNEDFAAHPGEDAVPTGPDCQAKSTPVIVSATTKKGLSSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GETLEPAGAHLVLEEKSSEKNEDFAAHPGEDAVPTGPDCQAKSTPVIVSATTKKGLSSDL 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 EGEKTTSLKWKSDEVDEQVACQEVKVSVAIEEDLEPENGILELETKSSKLVQNIIQTAVD ::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::: XP_016 EGEKTTSLKWKSDEVDEQVACQEVKVSVAIE-DLEPENGILELETKSSKLVQNIIQTAVD 1510 1520 1530 1540 1550 1570 1580 1590 1600 1610 1620 pF1KB0 QFVRTEETATEMLTSELQTQAHVIKADSQDAGQETEKEGEDPQASAQDETPITSAKEESE ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: XP_016 QFVRTEETATEMLTSELQTQAHVIKADSQDAGQETEKEGEEPQASAQDETPITSAKEESE 1560 1570 1580 1590 1600 1610 1630 1640 1650 1660 1670 1680 pF1KB0 STAVGQAHSDISKDMSEASEKTMTVEVEGSTVNDQQLEEVVLPSEEEGGGAGTKSVPEDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STAVGQAHSDISKDMSEASEKTMTVEVEGSTVNDQQLEEVVLPSEEEGGGAGTKSVPEDD 1620 1630 1640 1650 1660 1670 1690 1700 1710 1720 1730 1740 pF1KB0 GHALLAERIEKSLVEPKEDEKGDDVDDPENQNSALADTDASGGLTKESPDTNGPKQKEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHALLAERIEKSLVEPKEDEKGDDVDDPENQNSALADTDASGGLTKESPDTNGPKQKEKE 1680 1690 1700 1710 1720 1730 1750 1760 1770 1780 pF1KB0 DAQEVELQEGKVHSESDKAITPQAQEELQKQERESAKSELTES ::::::::::::::::::::::::::::::::::::::::::: XP_016 DAQEVELQEGKVHSESDKAITPQAQEELQKQERESAKSELTES 1740 1750 1760 1770 1780 >>NP_653080 (OMIM: 604698) A-kinase anchor protein 12 is (1684 aa) initn: 9073 init1: 9073 opt: 10617 Z-score: 6172.3 bits: 1155.2 E(85289): 0 Smith-Waterman score: 10617; 99.5% identity (99.8% similar) in 1681 aa overlap (103-1783:5-1684) 80 90 100 110 120 130 pF1KB0 ELSLQEGDLNGQKGALNGQGALNSQEEEEVIVTEVGQRDSEDVSERDSDKEMATKSAVVH :. ::::::::::.::::::::::::::: NP_653 MLGTITITVGQRDSEDVSKRDSDKEMATKSAVVH 10 20 30 140 150 160 170 180 190 pF1KB0 DITDDGQEETPEIIEQIPSSESNLEELTQPTESQANDIGFKKVFKFVGFKFTVKKDKTEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 DITDDGQEETPEIIEQIPSSESNLEELTQPTESQANDIGFKKVFKFVGFKFTVKKDKTEK 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB0 PDTVQLLTVKKDEGEGAAGAGDHQDPSLGAGEAASKESEPKQSTEKPEETLKREQSHAEI :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: NP_653 PDTVQLLTVKKDEGEGAAGAGDHKDPSLGAGEAASKESEPKQSTEKPEETLKREQSHAEI 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB0 SPPAESGQAVEECKEEGEEKQEKEPSKSAESPTSPVTSETGSTFKKFFTQGWAGWRKKTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 SPPAESGQAVEECKEEGEEKQEKEPSKSAESPTSPVTSETGSTFKKFFTQGWAGWRKKTS 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB0 FRKPKEDEVEASEKKKEQEPEKVDTEEDGKAEVASEKLTASEQAHPQEPAESAHEPRLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 FRKPKEDEVEASEKKKEQEPEKVDTEEDGKAEVASEKLTASEQAHPQEPAESAHEPRLSA 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB0 EYEKVELPSEEQVSGSQGPSEEKPAPLATEVFDEKIEVHQEEVVAEVHVSIVEERTEEQK :::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::: NP_653 EYEKVELPSEEQVSGSQGPSEEKPAPLATEVFDEKIEVHQEEVVAEVHVSTVEERTEEQK 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB0 TEVEETAGSVPAEELVEMDAEPQEAEPAKELVKLKETCVSGEDPTQGADLSPDEKVLSKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 TEVEETAGSVPAEELVEMDAEPQEAEPAKELVKLKETCVSGEDPTQGADLSPDEKVLSKP 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB0 PEGVVSEVEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGGDEESGEHTQVPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 PEGVVSEVEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGGDEESGEHTQVPA 400 410 420 430 440 450 560 570 580 590 600 610 pF1KB0 DSPDSQEEQKGESSASSPEEPEEITCLEKGLAEVQQDGEAEEGATSDGEKKREGVTPWAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 DSPDSQEEQKGESSASSPEEPEEITCLEKGLAEVQQDGEAEEGATSDGEKKREGVTPWAS 460 470 480 490 500 510 620 630 640 650 660 670 pF1KB0 FKKMVTPKKRVRRPSESDKEDELDKVKSATLSSTESTASEMQEEMKGSVEEPKPEEPKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 FKKMVTPKKRVRRPSESDKEDELDKVKSATLSSTESTASEMQEEMKGSVEEPKPEEPKRK 520 530 540 550 560 570 680 690 700 710 720 730 pF1KB0 VDTSVSWEALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 VDTSVSWEALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAGS 580 590 600 610 620 630 740 750 760 770 780 790 pF1KB0 QEHDPGQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVEHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 QEHDPGQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVEHS 640 650 660 670 680 690 800 810 820 830 840 850 pF1KB0 TPDTEPGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDSDVPAVVPLSEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 TPDTEPGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDSDVPAVVPLSEY 700 710 720 730 740 750 860 870 880 890 900 910 pF1KB0 DAVEREKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 DAVEREKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSPS 760 770 780 790 800 810 920 930 940 950 960 970 pF1KB0 WISASVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREARGDTVVSEAELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 WISASVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREARGDTVVSEAELT 820 830 840 850 860 870 980 990 1000 1010 1020 1030 pF1KB0 PEAVTAAETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEATPVQEVEGGVPDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 PEAVTAAETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEATPVQEVEGGVPDI 880 890 900 910 920 930 1040 1050 1060 1070 1080 1090 pF1KB0 EEQERRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQAEASGLKKETDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 EEQERRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQAEASGLKKETDV 940 950 960 970 980 990 1100 1110 1120 1130 1140 1150 pF1KB0 VLKVDAQEAKTEPFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQAETLAGVKSQEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 VLKVDAQEAKTEPFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQAETLAGVKSQEM 1000 1010 1020 1030 1040 1050 1160 1170 1180 1190 1200 1210 pF1KB0 VMEQAIPPDSVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEVASGTQSGGTEAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 VMEQAIPPDSVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEVASGTQSGGTEAE 1060 1070 1080 1090 1100 1110 1220 1230 1240 1250 1260 1270 pF1KB0 AVPAQKERPPAPSSFVFQEETKEQSKMEDTLEHTDKEVSVETVSILSKTEGTQEADQYAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 AVPAQKERPPAPSSFVFQEETKEQSKMEDTLEHTDKEVSVETVSILSKTEGTQEADQYAD 1120 1130 1140 1150 1160 1170 1280 1290 1300 1310 1320 1330 pF1KB0 EKTKDVPFFEGLEGSIDTGITVSREKVTEVALKGEGTEEAECKKDDALELQSHAKSPPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 EKTKDVPFFEGLEGSIDTGITVSREKVTEVALKGEGTEEAECKKDDALELQSHAKSPPSP 1180 1190 1200 1210 1220 1230 1340 1350 1360 1370 1380 1390 pF1KB0 VEREMVVQVEREKTEAEPTHVNEEKLEHETAVTVSEEVSKQLLQTVNVPIIDGAKEVSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 VEREMVVQVEREKTEAEPTHVNEEKLEHETAVTVSEEVSKQLLQTVNVPIIDGAKEVSSL 1240 1250 1260 1270 1280 1290 1400 1410 1420 1430 1440 1450 pF1KB0 EGSPPPCLGQEEAVCTKIQVQSSEASFTLTAAAEEEKVLGETANILETGETLEPAGAHLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 EGSPPPCLGQEEAVCTKIQVQSSEASFTLTAAAEEEKVLGETANILETGETLEPAGAHLV 1300 1310 1320 1330 1340 1350 1460 1470 1480 1490 1500 1510 pF1KB0 LEEKSSEKNEDFAAHPGEDAVPTGPDCQAKSTPVIVSATTKKGLSSDLEGEKTTSLKWKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 LEEKSSEKNEDFAAHPGEDAVPTGPDCQAKSTPVIVSATTKKGLSSDLEGEKTTSLKWKS 1360 1370 1380 1390 1400 1410 1520 1530 1540 1550 1560 1570 pF1KB0 DEVDEQVACQEVKVSVAIEEDLEPENGILELETKSSKLVQNIIQTAVDQFVRTEETATEM ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: NP_653 DEVDEQVACQEVKVSVAIE-DLEPENGILELETKSSKLVQNIIQTAVDQFVRTEETATEM 1420 1430 1440 1450 1460 1470 1580 1590 1600 1610 1620 1630 pF1KB0 LTSELQTQAHVIKADSQDAGQETEKEGEDPQASAQDETPITSAKEESESTAVGQAHSDIS ::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::: NP_653 LTSELQTQAHVIKADSQDAGQETEKEGEEPQASAQDETPITSAKEESESTAVGQAHSDIS 1480 1490 1500 1510 1520 1530 1640 1650 1660 1670 1680 1690 pF1KB0 KDMSEASEKTMTVEVEGSTVNDQQLEEVVLPSEEEGGGAGTKSVPEDDGHALLAERIEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 KDMSEASEKTMTVEVEGSTVNDQQLEEVVLPSEEEGGGAGTKSVPEDDGHALLAERIEKS 1540 1550 1560 1570 1580 1590 1700 1710 1720 1730 1740 1750 pF1KB0 LVEPKEDEKGDDVDDPENQNSALADTDASGGLTKESPDTNGPKQKEKEDAQEVELQEGKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 LVEPKEDEKGDDVDDPENQNSALADTDASGGLTKESPDTNGPKQKEKEDAQEVELQEGKV 1600 1610 1620 1630 1640 1650 1760 1770 1780 pF1KB0 HSESDKAITPQAQEELQKQERESAKSELTES ::::::::::::::::::::::::::::::: NP_653 HSESDKAITPQAQEELQKQERESAKSELTES 1660 1670 1680 >>XP_005267292 (OMIM: 604698) PREDICTED: A-kinase anchor (1677 aa) initn: 9070 init1: 9070 opt: 10614 Z-score: 6170.6 bits: 1154.9 E(85289): 0 Smith-Waterman score: 10614; 99.7% identity (99.9% similar) in 1677 aa overlap (107-1783:2-1677) 80 90 100 110 120 130 pF1KB0 QEGDLNGQKGALNGQGALNSQEEEEVIVTEVGQRDSEDVSERDSDKEMATKSAVVHDITD ::::::::::.::::::::::::::::::: XP_005 MVGQRDSEDVSKRDSDKEMATKSAVVHDITD 10 20 30 140 150 160 170 180 190 pF1KB0 DGQEETPEIIEQIPSSESNLEELTQPTESQANDIGFKKVFKFVGFKFTVKKDKTEKPDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DGQEETPEIIEQIPSSESNLEELTQPTESQANDIGFKKVFKFVGFKFTVKKDKTEKPDTV 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB0 QLLTVKKDEGEGAAGAGDHQDPSLGAGEAASKESEPKQSTEKPEETLKREQSHAEISPPA :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: XP_005 QLLTVKKDEGEGAAGAGDHKDPSLGAGEAASKESEPKQSTEKPEETLKREQSHAEISPPA 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB0 ESGQAVEECKEEGEEKQEKEPSKSAESPTSPVTSETGSTFKKFFTQGWAGWRKKTSFRKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ESGQAVEECKEEGEEKQEKEPSKSAESPTSPVTSETGSTFKKFFTQGWAGWRKKTSFRKP 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB0 KEDEVEASEKKKEQEPEKVDTEEDGKAEVASEKLTASEQAHPQEPAESAHEPRLSAEYEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KEDEVEASEKKKEQEPEKVDTEEDGKAEVASEKLTASEQAHPQEPAESAHEPRLSAEYEK 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB0 VELPSEEQVSGSQGPSEEKPAPLATEVFDEKIEVHQEEVVAEVHVSIVEERTEEQKTEVE :::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::: XP_005 VELPSEEQVSGSQGPSEEKPAPLATEVFDEKIEVHQEEVVAEVHVSTVEERTEEQKTEVE 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB0 ETAGSVPAEELVEMDAEPQEAEPAKELVKLKETCVSGEDPTQGADLSPDEKVLSKPPEGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ETAGSVPAEELVEMDAEPQEAEPAKELVKLKETCVSGEDPTQGADLSPDEKVLSKPPEGV 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB0 VSEVEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGGDEESGEHTQVPADSPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VSEVEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGGDEESGEHTQVPADSPD 400 410 420 430 440 450 560 570 580 590 600 610 pF1KB0 SQEEQKGESSASSPEEPEEITCLEKGLAEVQQDGEAEEGATSDGEKKREGVTPWASFKKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQEEQKGESSASSPEEPEEITCLEKGLAEVQQDGEAEEGATSDGEKKREGVTPWASFKKM 460 470 480 490 500 510 620 630 640 650 660 670 pF1KB0 VTPKKRVRRPSESDKEDELDKVKSATLSSTESTASEMQEEMKGSVEEPKPEEPKRKVDTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VTPKKRVRRPSESDKEDELDKVKSATLSSTESTASEMQEEMKGSVEEPKPEEPKRKVDTS 520 530 540 550 560 570 680 690 700 710 720 730 pF1KB0 VSWEALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAGSQEHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VSWEALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAGSQEHD 580 590 600 610 620 630 740 750 760 770 780 790 pF1KB0 PGQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVEHSTPDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PGQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVEHSTPDT 640 650 660 670 680 690 800 810 820 830 840 850 pF1KB0 EPGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDSDVPAVVPLSEYDAVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EPGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDSDVPAVVPLSEYDAVE 700 710 720 730 740 750 860 870 880 890 900 910 pF1KB0 REKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSPSWISA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 REKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSPSWISA 760 770 780 790 800 810 920 930 940 950 960 970 pF1KB0 SVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREARGDTVVSEAELTPEAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREARGDTVVSEAELTPEAV 820 830 840 850 860 870 980 990 1000 1010 1020 1030 pF1KB0 TAAETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEATPVQEVEGGVPDIEEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TAAETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEATPVQEVEGGVPDIEEQE 880 890 900 910 920 930 1040 1050 1060 1070 1080 1090 pF1KB0 RRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQAEASGLKKETDVVLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQAEASGLKKETDVVLKV 940 950 960 970 980 990 1100 1110 1120 1130 1140 1150 pF1KB0 DAQEAKTEPFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQAETLAGVKSQEMVMEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DAQEAKTEPFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQAETLAGVKSQEMVMEQ 1000 1010 1020 1030 1040 1050 1160 1170 1180 1190 1200 1210 pF1KB0 AIPPDSVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEVASGTQSGGTEAEAVPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AIPPDSVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEVASGTQSGGTEAEAVPA 1060 1070 1080 1090 1100 1110 1220 1230 1240 1250 1260 1270 pF1KB0 QKERPPAPSSFVFQEETKEQSKMEDTLEHTDKEVSVETVSILSKTEGTQEADQYADEKTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QKERPPAPSSFVFQEETKEQSKMEDTLEHTDKEVSVETVSILSKTEGTQEADQYADEKTK 1120 1130 1140 1150 1160 1170 1280 1290 1300 1310 1320 1330 pF1KB0 DVPFFEGLEGSIDTGITVSREKVTEVALKGEGTEEAECKKDDALELQSHAKSPPSPVERE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DVPFFEGLEGSIDTGITVSREKVTEVALKGEGTEEAECKKDDALELQSHAKSPPSPVERE 1180 1190 1200 1210 1220 1230 1340 1350 1360 1370 1380 1390 pF1KB0 MVVQVEREKTEAEPTHVNEEKLEHETAVTVSEEVSKQLLQTVNVPIIDGAKEVSSLEGSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MVVQVEREKTEAEPTHVNEEKLEHETAVTVSEEVSKQLLQTVNVPIIDGAKEVSSLEGSP 1240 1250 1260 1270 1280 1290 1400 1410 1420 1430 1440 1450 pF1KB0 PPCLGQEEAVCTKIQVQSSEASFTLTAAAEEEKVLGETANILETGETLEPAGAHLVLEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPCLGQEEAVCTKIQVQSSEASFTLTAAAEEEKVLGETANILETGETLEPAGAHLVLEEK 1300 1310 1320 1330 1340 1350 1460 1470 1480 1490 1500 1510 pF1KB0 SSEKNEDFAAHPGEDAVPTGPDCQAKSTPVIVSATTKKGLSSDLEGEKTTSLKWKSDEVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSEKNEDFAAHPGEDAVPTGPDCQAKSTPVIVSATTKKGLSSDLEGEKTTSLKWKSDEVD 1360 1370 1380 1390 1400 1410 1520 1530 1540 1550 1560 1570 pF1KB0 EQVACQEVKVSVAIEEDLEPENGILELETKSSKLVQNIIQTAVDQFVRTEETATEMLTSE ::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::: XP_005 EQVACQEVKVSVAIE-DLEPENGILELETKSSKLVQNIIQTAVDQFVRTEETATEMLTSE 1420 1430 1440 1450 1460 1470 1580 1590 1600 1610 1620 1630 pF1KB0 LQTQAHVIKADSQDAGQETEKEGEDPQASAQDETPITSAKEESESTAVGQAHSDISKDMS ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: XP_005 LQTQAHVIKADSQDAGQETEKEGEEPQASAQDETPITSAKEESESTAVGQAHSDISKDMS 1480 1490 1500 1510 1520 1530 1640 1650 1660 1670 1680 1690 pF1KB0 EASEKTMTVEVEGSTVNDQQLEEVVLPSEEEGGGAGTKSVPEDDGHALLAERIEKSLVEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EASEKTMTVEVEGSTVNDQQLEEVVLPSEEEGGGAGTKSVPEDDGHALLAERIEKSLVEP 1540 1550 1560 1570 1580 1590 1700 1710 1720 1730 1740 1750 pF1KB0 KEDEKGDDVDDPENQNSALADTDASGGLTKESPDTNGPKQKEKEDAQEVELQEGKVHSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KEDEKGDDVDDPENQNSALADTDASGGLTKESPDTNGPKQKEKEDAQEVELQEGKVHSES 1600 1610 1620 1630 1640 1650 1760 1770 1780 pF1KB0 DKAITPQAQEELQKQERESAKSELTES ::::::::::::::::::::::::::: XP_005 DKAITPQAQEELQKQERESAKSELTES 1660 1670 >>XP_016867007 (OMIM: 604698) PREDICTED: A-kinase anchor (1659 aa) initn: 8965 init1: 8965 opt: 10509 Z-score: 6109.7 bits: 1143.6 E(85289): 0 Smith-Waterman score: 10509; 99.8% identity (99.9% similar) in 1660 aa overlap (124-1783:1-1659) 100 110 120 130 140 150 pF1KB0 LNSQEEEEVIVTEVGQRDSEDVSERDSDKEMATKSAVVHDITDDGQEETPEIIEQIPSSE :::::::::::::::::::::::::::::: XP_016 MATKSAVVHDITDDGQEETPEIIEQIPSSE 10 20 30 160 170 180 190 200 210 pF1KB0 SNLEELTQPTESQANDIGFKKVFKFVGFKFTVKKDKTEKPDTVQLLTVKKDEGEGAAGAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SNLEELTQPTESQANDIGFKKVFKFVGFKFTVKKDKTEKPDTVQLLTVKKDEGEGAAGAG 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB0 DHQDPSLGAGEAASKESEPKQSTEKPEETLKREQSHAEISPPAESGQAVEECKEEGEEKQ ::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DHKDPSLGAGEAASKESEPKQSTEKPEETLKREQSHAEISPPAESGQAVEECKEEGEEKQ 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB0 EKEPSKSAESPTSPVTSETGSTFKKFFTQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKEPSKSAESPTSPVTSETGSTFKKFFTQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPE 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB0 KVDTEEDGKAEVASEKLTASEQAHPQEPAESAHEPRLSAEYEKVELPSEEQVSGSQGPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVDTEEDGKAEVASEKLTASEQAHPQEPAESAHEPRLSAEYEKVELPSEEQVSGSQGPSE 220 230 240 250 260 270 400 410 420 430 440 450 pF1KB0 EKPAPLATEVFDEKIEVHQEEVVAEVHVSIVEERTEEQKTEVEETAGSVPAEELVEMDAE ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::: XP_016 EKPAPLATEVFDEKIEVHQEEVVAEVHVSTVEERTEEQKTEVEETAGSVPAEELVEMDAE 280 290 300 310 320 330 460 470 480 490 500 510 pF1KB0 PQEAEPAKELVKLKETCVSGEDPTQGADLSPDEKVLSKPPEGVVSEVEMLSSQERMKVQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQEAEPAKELVKLKETCVSGEDPTQGADLSPDEKVLSKPPEGVVSEVEMLSSQERMKVQG 340 350 360 370 380 390 520 530 540 550 560 570 pF1KB0 SPLKKLFTSTGLKKLSGKKQKGKRGGGDEESGEHTQVPADSPDSQEEQKGESSASSPEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPLKKLFTSTGLKKLSGKKQKGKRGGGDEESGEHTQVPADSPDSQEEQKGESSASSPEEP 400 410 420 430 440 450 580 590 600 610 620 630 pF1KB0 EEITCLEKGLAEVQQDGEAEEGATSDGEKKREGVTPWASFKKMVTPKKRVRRPSESDKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEITCLEKGLAEVQQDGEAEEGATSDGEKKREGVTPWASFKKMVTPKKRVRRPSESDKED 460 470 480 490 500 510 640 650 660 670 680 690 pF1KB0 ELDKVKSATLSSTESTASEMQEEMKGSVEEPKPEEPKRKVDTSVSWEALICVGSSKKRAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELDKVKSATLSSTESTASEMQEEMKGSVEEPKPEEPKRKVDTSVSWEALICVGSSKKRAR 520 530 540 550 560 570 700 710 720 730 740 750 pF1KB0 RGSSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAGSQEHDPGQGSSSPEQAGSPTEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGSSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAGSQEHDPGQGSSSPEQAGSPTEG 580 590 600 610 620 630 760 770 780 790 800 810 pF1KB0 EGVSTWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVEHSTPDTEPGKEESWVSIKKFIPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGVSTWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVEHSTPDTEPGKEESWVSIKKFIPG 640 650 660 670 680 690 820 830 840 850 860 870 pF1KB0 RRKKRPDGKQEQAPVEDAGPTGANEDDSDVPAVVPLSEYDAVEREKMEAQQAQKSAEQPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRKKRPDGKQEQAPVEDAGPTGANEDDSDVPAVVPLSEYDAVEREKMEAQQAQKSAEQPE 700 710 720 730 740 750 880 890 900 910 920 930 pF1KB0 QKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSPSWISASVTEPLEQVEAEAALLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSPSWISASVTEPLEQVEAEAALLT 760 770 780 790 800 810 940 950 960 970 980 990 pF1KB0 EEVLEREVIAEEEPPTVTEPLPENREARGDTVVSEAELTPEAVTAAETAGPLGAEEGTEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEVLEREVIAEEEPPTVTEPLPENREARGDTVVSEAELTPEAVTAAETAGPLGAEEGTEA 820 830 840 850 860 870 1000 1010 1020 1030 1040 1050 pF1KB0 SAAEETTEMVSAVSQLTDSPDTTEEATPVQEVEGGVPDIEEQERRTQEVLQAVAEKVKEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAAEETTEMVSAVSQLTDSPDTTEEATPVQEVEGGVPDIEEQERRTQEVLQAVAEKVKEE 880 890 900 910 920 930 1060 1070 1080 1090 1100 1110 pF1KB0 SQLPGTGGPEDVLQPVQRAEAERPEEQAEASGLKKETDVVLKVDAQEAKTEPFTQGKVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQLPGTGGPEDVLQPVQRAEAERPEEQAEASGLKKETDVVLKVDAQEAKTEPFTQGKVVG 940 950 960 970 980 990 1120 1130 1140 1150 1160 1170 pF1KB0 QTTPESFEKAPQVTESIESSELVTTCQAETLAGVKSQEMVMEQAIPPDSVETPTDSETDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QTTPESFEKAPQVTESIESSELVTTCQAETLAGVKSQEMVMEQAIPPDSVETPTDSETDG 1000 1010 1020 1030 1040 1050 1180 1190 1200 1210 1220 1230 pF1KB0 STPVADFDAPGTTQKDEIVEIHEENEVASGTQSGGTEAEAVPAQKERPPAPSSFVFQEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STPVADFDAPGTTQKDEIVEIHEENEVASGTQSGGTEAEAVPAQKERPPAPSSFVFQEET 1060 1070 1080 1090 1100 1110 1240 1250 1260 1270 1280 1290 pF1KB0 KEQSKMEDTLEHTDKEVSVETVSILSKTEGTQEADQYADEKTKDVPFFEGLEGSIDTGIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEQSKMEDTLEHTDKEVSVETVSILSKTEGTQEADQYADEKTKDVPFFEGLEGSIDTGIT 1120 1130 1140 1150 1160 1170 1300 1310 1320 1330 1340 1350 pF1KB0 VSREKVTEVALKGEGTEEAECKKDDALELQSHAKSPPSPVEREMVVQVEREKTEAEPTHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSREKVTEVALKGEGTEEAECKKDDALELQSHAKSPPSPVEREMVVQVEREKTEAEPTHV 1180 1190 1200 1210 1220 1230 1360 1370 1380 1390 1400 1410 pF1KB0 NEEKLEHETAVTVSEEVSKQLLQTVNVPIIDGAKEVSSLEGSPPPCLGQEEAVCTKIQVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEEKLEHETAVTVSEEVSKQLLQTVNVPIIDGAKEVSSLEGSPPPCLGQEEAVCTKIQVQ 1240 1250 1260 1270 1280 1290 1420 1430 1440 1450 1460 1470 pF1KB0 SSEASFTLTAAAEEEKVLGETANILETGETLEPAGAHLVLEEKSSEKNEDFAAHPGEDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSEASFTLTAAAEEEKVLGETANILETGETLEPAGAHLVLEEKSSEKNEDFAAHPGEDAV 1300 1310 1320 1330 1340 1350 1480 1490 1500 1510 1520 1530 pF1KB0 PTGPDCQAKSTPVIVSATTKKGLSSDLEGEKTTSLKWKSDEVDEQVACQEVKVSVAIEED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_016 PTGPDCQAKSTPVIVSATTKKGLSSDLEGEKTTSLKWKSDEVDEQVACQEVKVSVAIE-D 1360 1370 1380 1390 1400 1540 1550 1560 1570 1580 1590 pF1KB0 LEPENGILELETKSSKLVQNIIQTAVDQFVRTEETATEMLTSELQTQAHVIKADSQDAGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEPENGILELETKSSKLVQNIIQTAVDQFVRTEETATEMLTSELQTQAHVIKADSQDAGQ 1410 1420 1430 1440 1450 1460 1600 1610 1620 1630 1640 1650 pF1KB0 ETEKEGEDPQASAQDETPITSAKEESESTAVGQAHSDISKDMSEASEKTMTVEVEGSTVN :::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETEKEGEEPQASAQDETPITSAKEESESTAVGQAHSDISKDMSEASEKTMTVEVEGSTVN 1470 1480 1490 1500 1510 1520 1660 1670 1680 1690 1700 1710 pF1KB0 DQQLEEVVLPSEEEGGGAGTKSVPEDDGHALLAERIEKSLVEPKEDEKGDDVDDPENQNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQQLEEVVLPSEEEGGGAGTKSVPEDDGHALLAERIEKSLVEPKEDEKGDDVDDPENQNS 1530 1540 1550 1560 1570 1580 1720 1730 1740 1750 1760 1770 pF1KB0 ALADTDASGGLTKESPDTNGPKQKEKEDAQEVELQEGKVHSESDKAITPQAQEELQKQER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALADTDASGGLTKESPDTNGPKQKEKEDAQEVELQEGKVHSESDKAITPQAQEELQKQER 1590 1600 1610 1620 1630 1640 1780 pF1KB0 ESAKSELTES :::::::::: XP_016 ESAKSELTES 1650 >>NP_849188 (OMIM: 608581,613587) retinitis pigmentosa 1 (2400 aa) initn: 198 init1: 88 opt: 311 Z-score: 190.2 bits: 48.8 E(85289): 0.00075 Smith-Waterman score: 496; 25.4% identity (51.8% similar) in 1090 aa overlap (202-1224:1277-2283) 180 190 200 210 220 230 pF1KB0 FKKVFKFVGFKFTVKKDKTEKPDTVQLLTVKKDEGEGAAGAGDHQDPSLGAGEAASKESE ..: : :... .: . : .. : : NP_849 PGDLENQQQCCFPTFLNARACACATNEDEAERDSEEQRASSNLEQLAENTVQEEVQLE-E 1250 1260 1270 1280 1290 1300 240 250 260 270 280 pF1KB0 PKQSTEKP---EETLKREQSHAEISPPAESGQAVEECKE-EGEEKQEKEPS-KSAESPTS :..:: ::... :....: : : .:: :: ::: .::.: . . : . NP_849 TKEGTEGEGLQEEAVQLEETKTE-EGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGG 1310 1320 1330 1340 1350 1360 290 300 310 320 330 340 pF1KB0 PVTSETGSTF---KKFFTQGWAGWRKKTSFRK---PKEDEVEASEKKKEQEPEKVDTEED .: : . :. : : . .... :.: :...: .. . :. ..:: NP_849 EGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQED 1370 1380 1390 1400 1410 1420 350 360 370 380 390 pF1KB0 GKAEVASEKLTASEQAHPQEPAESAHEPRLSAEYEKVELPSE-EQVSGSQ-GPSEEKPAP .. : :: .:.: :::...:: . . :: :. :::: :. ::: : NP_849 DPVQ-EEEAGRASASAEPC-PAEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLEKP-P 1430 1440 1450 1460 1470 1480 400 410 420 430 440 pF1KB0 LATEVFDEKIEVHQEEVVAE---------------VHVSIVEERTEEQKTEVEETAGSVP :: . .:. ... . .:: . ::.. ..:: :. . . :..: NP_849 GATMMGQEHTQAQPTQGAAERSSSVACSAALDCDPIWVSVLLKKTE--KAFLAHLASAVA 1490 1500 1510 1520 1530 450 460 470 480 490 pF1KB0 AEE----LVEMDAEPQEAEPAKELV--KLKETCVSGEDPTQGADLSPDEKVLSKPPEGVV . : . : : : .. : .:... . :: . :: : :... NP_849 ELRARWGLQDNDLLDQMAAELQQDVAQRLQDSTKRELQKLQG---RAGRMVLEPPREALT 1540 1550 1560 1570 1580 1590 500 510 520 530 540 pF1KB0 SEVEMLSSQERMKVQGSPLKKL--FT--STGLKKLSGKKQK--------GKRGGGDEESG .:. . ..:.: ...: :..: :. . :: :: . :.. : . :. NP_849 GELLLQTQQRRHRLRG--LRNLSAFSERTLGLGPLSFTLEDEPALSTALGSQLGEEAEGE 1600 1610 1620 1630 1640 1650 550 560 570 580 590 pF1KB0 EHTQVPAD-----SPDSQEEQKGESSASSPEEPEEITCLEKGLAEVQQDGEAEE---GAT : : :: : . : . . : . :.. .: . :::: : : : NP_849 EFCPCEACVRKKVSPMSPKATMGATRGPIKEAFDLQQILQRKRGE-HTDGEAAEVAPGKT 1660 1670 1680 1690 1700 1710 600 610 620 630 640 650 pF1KB0 -SDGEKKREGVTPWASFKKMVTPKKRVRRPSESDKEDELDKVKSATLSSTESTASEMQEE .: . : ... .. : . ... ..:.. :. :. .:. : : .: NP_849 HTDPTSTRTVQGAEGGLGPGLSQGPGVDEGEDGEGSQRLNRDKDPKLGEAEGDA--MAQE 1720 1730 1740 1750 1760 1770 660 670 680 690 700 710 pF1KB0 MKGSVEEPKPEEPKRKVDTSVSWEALICVGSSKKRARRGSSSDEEG---GPKAMGGDHQK .: : .. . .. . .. : :.. :..: .: : : :::. NP_849 REG-----KTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQ-- 1780 1790 1800 1810 1820 720 730 740 750 760 770 pF1KB0 ADEAGKDKETGTDGILAGSQEHDPGQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSK : . .: : .. : .. . ..: .:: :. :.:: . :: . . .:. ... NP_849 -DPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPES-EDVEAPEAEGE 1830 1840 1850 1860 1870 1880 780 790 800 810 820 830 pF1KB0 SKLEEKSEDSIAGSGVEHSTPDTEPGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGP .. : ::: :: ::..: : . .:... .:: .: NP_849 AQPE--SED------VE--TPEAE------W-----------EVQPESEGAEAP--EAEK 1890 1900 1910 840 850 860 870 880 890 pF1KB0 TGANEDDSDVPAVVPLSEYDAVEREKMEAQQAQKSAEQPEQKAATEVSKELSESQ-VHMM . : .: : :. .: : : : :::.:...:.. : .. : .:. ::: .. NP_849 EAQPETES-VEALETEGE-DEPESEGAEAQEAEEAAQEAEGQTQPE--SEVIESQEAEEE 1920 1930 1940 1950 1960 900 910 920 930 940 pF1KB0 AAAVADGTRAATI-IEERSPSWISASVTEPLEQVEAEAALLT--EEVLEREVIAEEEPPT : .. ..: . .: . . .: .: :::. . ::. . .: .: . NP_849 AQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKS 1970 1980 1990 2000 2010 2020 950 960 970 980 990 1000 pF1KB0 VTEPLPENREARGDTVVSEAELTPEAVTAAETAGPLGAEEGTEASA-AEETTEMVSAVSQ : : .:..:.: .:.. ::. ..: .: . ::. :: . ..:. . :. NP_849 EGE---EAQEVEGETQKTEGDAQPES-DGVE--APEAEEEAQEAEGEVQEAEGEAHPESE 2030 2040 2050 2060 2070 2080 1010 1020 1030 1040 1050 1060 pF1KB0 LTDSPDTTEEATPVQEVEGGVPDIEEQERRTQEVLQAVAEKVKEESQLPGTGGPEDVLQP .:. .. :: : .: :: . : : ..:.. : ... :.: : . : : : NP_849 DVDAQEAEGEAQPESE---GV-EAPEAEGEAQKAEGIEAPETEGEAQ-PESEGIE---AP 2090 2100 2110 2120 2130 1070 1080 1090 1100 1110 1120 pF1KB0 VQRAEAERPEEQAEASGLKKETDVVLK-VDAQEAKTEPFTQGKVVGQTTPESFEKAPQVT ..::. : .::. . :.. . ..::::. : .: .. : .::. .: . NP_849 EAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEE--AQPELEGVEAPEAEGEAQPES 2140 2150 2160 2170 2180 2190 1130 1140 1150 1160 1170 1180 pF1KB0 ESIESSELVTTCQAETLAGVKSQEMVMEQAIP-PDSVETPTDSETDG-STPVADFDAPGT :.::. : : : : ::.. : . :.: : :..:::: :..: . : .. .. : NP_849 EGIEAPEAEGEAQPE-LEGVEAPE-AEEEAQPEPEGVETP---EAEGEAQPESEGETQGE 2200 2210 2220 2230 2240 1190 1200 1210 1220 1230 1240 pF1KB0 TQKDEIVEIHE-ENEVASGTQSGGTEAEAVPAQKERPPAPSSFVFQEETKEQSKMEDTLE . . : . . ..: :: ..: : . .: ::.: NP_849 KKGSPQVSLGDGQSEEASESSSPVPEDRPTP-----PPSPGGDTPHQRPGSQTGPSSSRA 2250 2260 2270 2280 2290 2300 1250 1260 1270 1280 1290 1300 pF1KB0 HTDKEVSVETVSILSKTEGTQEADQYADEKTKDVPFFEGLEGSIDTGITVSREKVTEVAL NP_849 SSWGNCWQKDSENDHVLGDTRSPDAKSTGTPHAERKATRMYPESSTSEQEEAPLGSRTPE 2310 2320 2330 2340 2350 2360 1783 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 22:32:38 2016 done: Wed Nov 2 22:32:40 2016 Total Scan time: 18.700 Total Display time: 0.600 Function used was FASTA [36.3.4 Apr, 2011]