FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0038, 389 aa 1>>>pF1KB0038 389 - 389 aa - 389 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.4014+/-0.000989; mu= 4.5809+/- 0.060 mean_var=231.6085+/-46.426, 0's: 0 Z-trim(113.0): 68 B-trim: 9 in 1/50 Lambda= 0.084275 statistics sampled from 13634 (13690) to 13634 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.758), E-opt: 0.2 (0.421), width: 16 Scan time: 3.130 The best scores are: opt bits E(32554) CCDS11765.1 CBX8 gene_id:57332|Hs108|chr17 ( 389) 2577 326.0 3.7e-89 CCDS13980.1 CBX6 gene_id:23466|Hs108|chr22 ( 412) 613 87.2 2.9e-17 CCDS77675.1 CBX6 gene_id:23466|Hs108|chr22 ( 394) 529 77.0 3.4e-14 >>CCDS11765.1 CBX8 gene_id:57332|Hs108|chr17 (389 aa) initn: 2577 init1: 2577 opt: 2577 Z-score: 1714.1 bits: 326.0 E(32554): 3.7e-89 Smith-Waterman score: 2577; 99.7% identity (99.7% similar) in 389 aa overlap (1-389:1-389) 10 20 30 40 50 60 pF1KB0 MELSAVGERVFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MELSAVGERVFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 EREMELYGPKKRGPKPKTFLLKAQAKAKAKTYEFRSDSARGIRIPYPGRSPQDLASTSRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 EREMELYGPKKRGPKPKTFLLKAQAKAKAKTYEFRSDSARGIRIPYPGRSPQDLASTSRA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 REGLRNMGLSPPASSTSTSSTCRAEAPRDRDRDRDRDRERDRERERERERERERERERER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 REGLRNMGLSPPASSTSTSSTCRAEAPRDRDRDRDRDRERDRERERERERERERERERER 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 GTSRVDDKPSSPGDSSKKRGPKPRKELPDPSQRPLGEPSAGLGEYLKGRKLDDTPSGAGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 GTSRVDDKPSSPGDSSKKRGPKPRKELPDPSQRPLGEPSAGLGEYLKGRKLDDTPSGAGK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 FPAGHSVIQLARRQDSDLVQCGVTSPSSAEATGKLAVDTFPARVIKHRAAFLEAKGQGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 FPAGHSVIQLARRQDSDLVQCGVTSPSSAEATGKLAVDTFPARVIKHRAAFLEAKGQGAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 DPNGTRVRHGSGPPSSVGGLYRDMGAQGGRPSLIARIPVARILGDPEEESWSPSLTNLEK :::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::: CCDS11 DPNGTRVRHGSGPPSSGGGLYRDMGAQGGRPSLIARIPVARILGDPEEESWSPSLTNLEK 310 320 330 340 350 360 370 380 pF1KB0 VVVTDVTSNFLTVTIKESNTDQGFFKEKR ::::::::::::::::::::::::::::: CCDS11 VVVTDVTSNFLTVTIKESNTDQGFFKEKR 370 380 >>CCDS13980.1 CBX6 gene_id:23466|Hs108|chr22 (412 aa) initn: 683 init1: 517 opt: 613 Z-score: 423.3 bits: 87.2 E(32554): 2.9e-17 Smith-Waterman score: 625; 36.3% identity (54.9% similar) in 419 aa overlap (1-386:1-393) 10 20 30 40 50 60 pF1KB0 MELSAVGERVFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEER ::::::::::::::...::::::::.:::::::::. :::::::::::::.::.::::.. CCDS13 MELSAVGERVFAAESIIKRRIRKGRIEYLVKWKGWAIKYSTWEPEENILDSRLIAAFEQK 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 EREMELYGPKKRGPKPKTFLLKAQAKAKAKTYEFRSDSARGIRIPYPGRSPQ--DLASTS ::: :::::::::::::::::::.:.:.: :: ... . ::. . :.. CCDS13 ERERELYGPKKRGPKPKTFLLKARAQAEALRI---SDVHFSVKPSASASSPKLHSSAAVH 70 80 90 100 110 120 130 140 150 pF1KB0 RAREGLR------------------NMGLSPPAS--STSTSSTCRAEAPRDRDRDRD--- : .. .: . :: :: : : .. : ::. :.: CCDS13 RLKKDIRRCHRMSRRPLPRPDPQGGSPGLRPPISPFSETVRIINRKVKPREPKRNRIILN 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB0 -RDRERDRERERERERERERERERERGTSRVDDKPSSPGDSSKKRGPKPRK----ELPDP . .. . : . . .:: : .. ..: . . : : : CCDS13 LKVIDKGAGGGGAGQGAGALARPKVPSRNRVIGKSKKFSESVLRTQIRHMKFGAFALYKP 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB0 SQRPLGEPSAGLGEYLKGRKLDDTPSGAGKFPAGHSVIQLARRQDSDLVQCGVTSPSSAE :: :: : : . . : : . :. .. :: . :. : .:.:.. CCDS13 PPAPLVAPSPG--------KAEASAPGPGLLLAAPAAPYDARSSGSS--GCPSPTPQSSD 240 250 260 270 280 280 290 300 310 320 pF1KB0 ATGKLAVDTFPARVIKHRAAFLEAKGQGALDPNGTRVRHGSGPPSSVGGLYR---DMGAQ : : ... . .. .. . .:. : : :: :.. : .. : CCDS13 P------DDTPPKLLPETVS---PSAPSWREPE---VLDLSLPPESAATSKRAPPEVTAA 290 300 310 320 330 330 340 350 360 370 380 pF1KB0 GGRPSLIARIPVARILGDPEEESWSPSLTNLEKVVVTDVTSNFLTVTIKESNTDQGFFKE .: : : : ..:: .: : .. .:::::::::.::::::: . . : : CCDS13 AGPAPPTAPEP-AGASSEPEAGDWRPEMSPCSNVVVTDVTSNLLTVTIKEFCNPEDFEKV 340 350 360 370 380 390 pF1KB0 KR CCDS13 AAGVAGAAGGGGSIGASK 400 410 >>CCDS77675.1 CBX6 gene_id:23466|Hs108|chr22 (394 aa) initn: 671 init1: 503 opt: 529 Z-score: 368.4 bits: 77.0 E(32554): 3.4e-14 Smith-Waterman score: 627; 37.2% identity (55.5% similar) in 409 aa overlap (1-386:1-375) 10 20 30 40 50 60 pF1KB0 MELSAVGERVFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEER ::::::::::::::...::::::::.:::::::::. :::::::::::::.::.::::.. CCDS77 MELSAVGERVFAAESIIKRRIRKGRIEYLVKWKGWAIKYSTWEPEENILDSRLIAAFEQK 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 EREMELYGPKKRGPKPKTFLLKAQAKAK-------AKTYEFRSDSARGIRI---PYPGRS ::: :::::::::::::::::: .:.:. : ......: : :. : : . CCDS77 ERERELYGPKKRGPKPKTFLLKPSASASSPKLHSSAAVHRLKKDIRRCHRMSRRPLPRPD 70 80 90 100 110 120 120 130 140 150 160 pF1KB0 PQDLASTSRAREGLRNMGLSPPAS--STSTSSTCRAEAPRDRDRDRD----RDRERDRER :: . ::: :: : : .. : ::. :.: . .. CCDS77 PQG------GSPGLR-----PPISPFSETVRIINRKVKPREPKRNRIILNLKVIDKGAGG 130 140 150 160 170 180 190 200 210 220 pF1KB0 ERERERERERERERERGTSRVDDKPSSPGDSSKKRGPKPRK----ELPDPSQRPLGEPSA . : . . .:: : .. ..: . . : : : :: :: CCDS77 GGAGQGAGALARPKVPSRNRVIGKSKKFSESVLRTQIRHMKFGAFALYKPPPAPLVAPSP 170 180 190 200 210 220 230 240 250 260 270 280 pF1KB0 GLGEYLKGRKLDDTPSGAGKFPAGHSVIQLARRQDSDLVQCGVTSPSSAEATGKLAVDTF : : . . : : . :. .. :: . :. : .:.:.. : CCDS77 G--------KAEASAPGPGLLLAAPAAPYDARSSGSS--GCPSPTPQSSDP------DDT 230 240 250 260 270 290 300 310 320 330 pF1KB0 PARVIKHRAAFLEAKGQGALDPNGTRVRHGSGPPSSVGGLYR---DMGAQGGRPSLIARI : ... . .. .. . .:. : : :: :.. : .. : .: : CCDS77 PPKLLPETVS---PSAPSWREPE---VLDLSLPPESAATSKRAPPEVTAAAGPAPPTAPE 280 290 300 310 320 340 350 360 370 380 pF1KB0 PVARILGDPEEESWSPSLTNLEKVVVTDVTSNFLTVTIKESNTDQGFFKEKR : : ..:: .: : .. .:::::::::.::::::: . . : : CCDS77 P-AGASSEPEAGDWRPEMSPCSNVVVTDVTSNLLTVTIKEFCNPEDFEKVAAGVAGAAGG 330 340 350 360 370 380 CCDS77 GGSIGASK 390 389 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 20:21:16 2016 done: Thu Nov 3 20:21:17 2016 Total Scan time: 3.130 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]