FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0045, 1433 aa 1>>>pF1KB0045 1433 - 1433 aa - 1433 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.9244+/-0.00049; mu= -8.2436+/- 0.030 mean_var=369.0983+/-77.376, 0's: 0 Z-trim(118.4): 100 B-trim: 0 in 0/57 Lambda= 0.066758 statistics sampled from 31140 (31245) to 31140 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.678), E-opt: 0.2 (0.366), width: 16 Scan time: 19.800 The best scores are: opt bits E(85289) NP_001265139 (OMIM: 603948) nuclear pore complex p (1433) 9365 917.7 0 XP_005249564 (OMIM: 603948) PREDICTED: nuclear por (1457) 5698 564.5 2.1e-159 NP_005115 (OMIM: 603948) nuclear pore complex prot (1475) 5698 564.5 2.1e-159 NP_001265138 (OMIM: 603948) nuclear pore complex p (1506) 5698 564.5 2.2e-159 XP_016867083 (OMIM: 603948) PREDICTED: nuclear por (1451) 5696 564.3 2.4e-159 XP_006715353 (OMIM: 603948) PREDICTED: nuclear por (1469) 5692 563.9 3.2e-159 XP_011513330 (OMIM: 603948) PREDICTED: nuclear por (1410) 4274 427.3 4e-118 XP_006715354 (OMIM: 603948) PREDICTED: nuclear por ( 839) 3752 376.9 3.6e-103 XP_011509878 (OMIM: 601181,608033) PREDICTED: E3 S (3199) 541 68.0 1.3e-09 XP_016860112 (OMIM: 601181,608033) PREDICTED: E3 S (2807) 538 67.7 1.4e-09 NP_006258 (OMIM: 601181,608033) E3 SUMO-protein li (3224) 538 67.8 1.6e-09 XP_005264062 (OMIM: 601181,608033) PREDICTED: E3 S (3232) 538 67.8 1.6e-09 XP_005264061 (OMIM: 601181,608033) PREDICTED: E3 S (3232) 538 67.8 1.6e-09 XP_005264060 (OMIM: 601181,608033) PREDICTED: E3 S (3250) 538 67.8 1.6e-09 XP_011509877 (OMIM: 601181,608033) PREDICTED: E3 S (3257) 538 67.8 1.6e-09 XP_005264059 (OMIM: 601181,608033) PREDICTED: E3 S (3258) 538 67.8 1.6e-09 XP_011514552 (OMIM: 158371) PREDICTED: mucin-3A is (3076) 456 59.8 3.6e-07 NP_005951 (OMIM: 158371) mucin-3A precursor [Homo (3323) 455 59.8 4.1e-07 XP_011514549 (OMIM: 158371) PREDICTED: mucin-3A is (3296) 444 58.7 8.6e-07 XP_011514551 (OMIM: 158371) PREDICTED: mucin-3A is (3245) 437 58.0 1.4e-06 XP_016867720 (OMIM: 158371) PREDICTED: mucin-3A is (3143) 435 57.8 1.5e-06 XP_011514548 (OMIM: 158371) PREDICTED: mucin-3A is (3313) 429 57.3 2.3e-06 NP_001035194 (OMIM: 608424) mucin-17 precursor [Ho (4493) 369 51.6 0.00016 NP_001291288 (OMIM: 158373) mucin-5AC precursor [H (5654) 356 50.4 0.00047 NP_001305254 (OMIM: 114350,613065) nuclear pore co ( 916) 304 44.8 0.0035 XP_005272275 (OMIM: 114350,613065) PREDICTED: nucl (2083) 311 45.8 0.0043 XP_005272276 (OMIM: 114350,613065) PREDICTED: nucl (2036) 304 45.1 0.0067 NP_001305253 (OMIM: 114350,613065) nuclear pore co (2080) 304 45.1 0.0068 NP_005076 (OMIM: 114350,613065) nuclear pore compl (2090) 304 45.1 0.0068 XP_016870656 (OMIM: 114350,613065) PREDICTED: nucl (2119) 304 45.1 0.0069 XP_011517355 (OMIM: 114350,613065) PREDICTED: nucl (2120) 304 45.1 0.0069 XP_006717355 (OMIM: 114350,613065) PREDICTED: nucl (2120) 304 45.1 0.0069 XP_005272273 (OMIM: 114350,613065) PREDICTED: nucl (2132) 304 45.1 0.0069 >>NP_001265139 (OMIM: 603948) nuclear pore complex prote (1433 aa) initn: 9365 init1: 9365 opt: 9365 Z-score: 4891.6 bits: 917.7 E(85289): 0 Smith-Waterman score: 9365; 100.0% identity (100.0% similar) in 1433 aa overlap (1-1433:1-1433) 10 20 30 40 50 60 pF1KB0 MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 KNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTAS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 NYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 YGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 RESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPIT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 SSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSGFASPKIDSVAAQPTATSPVVYTRPAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSGFASPKIDSVAAQPTATSPVVYTRPAI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 SGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 VSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 SSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 SGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 INPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 INPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 SNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 FTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 DNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTAD 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 QGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGN 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 TAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTF 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 GTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSS 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 pF1KB0 TPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFSGRKIKTAVRRRK ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFSGRKIKTAVRRRK 1390 1400 1410 1420 1430 >>XP_005249564 (OMIM: 603948) PREDICTED: nuclear pore co (1457 aa) initn: 7843 init1: 5632 opt: 5698 Z-score: 2982.8 bits: 564.5 E(85289): 2.1e-159 Smith-Waterman score: 9106; 95.9% identity (95.9% similar) in 1475 aa overlap (1-1433:1-1457) 10 20 30 40 50 60 pF1KB0 MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 KNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTAS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 NYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 YGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ :::::::::::::::::::::::::::::::::::::: :::: XP_005 YGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNS------------------VDSQ 310 320 330 340 370 380 390 400 410 420 pF1KB0 YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQ 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB0 RESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPIT 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB0 SSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL 470 480 490 500 510 520 550 560 570 pF1KB0 PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSS--------------------------- ::::::::::::::::::::::::::::::::: XP_005 PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPA 530 540 550 560 570 580 580 590 600 610 pF1KB0 ---------------GFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGS ::::::::::::::::::::::::::::::::::::::::::::: XP_005 EILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGS 590 600 610 620 630 640 620 630 640 650 660 670 pF1KB0 SWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFK 650 660 670 680 690 700 680 690 700 710 720 730 pF1KB0 PVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVT 710 720 730 740 750 760 740 750 760 770 780 790 pF1KB0 TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSG 770 780 790 800 810 820 800 810 820 830 840 850 pF1KB0 GSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAAS 830 840 850 860 870 880 860 870 880 890 900 910 pF1KB0 SSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFK 890 900 910 920 930 940 920 930 940 950 960 970 pF1KB0 FGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSA 950 960 970 980 990 1000 980 990 1000 1010 1020 1030 pF1KB0 GFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKG 1010 1020 1030 1040 1050 1060 1040 1050 1060 1070 1080 1090 pF1KB0 GFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQ 1070 1080 1090 1100 1110 1120 1100 1110 1120 1130 1140 1150 pF1KB0 TKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSS 1130 1140 1150 1160 1170 1180 1160 1170 1180 1190 1200 1210 pF1KB0 STPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 STPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKL 1190 1200 1210 1220 1230 1240 1220 1230 1240 1250 1260 1270 pF1KB0 ATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFG 1250 1260 1270 1280 1290 1300 1280 1290 1300 1310 1320 1330 pF1KB0 ANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1310 1320 1330 1340 1350 1360 1340 1350 1360 1370 1380 1390 pF1KB0 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1370 1380 1390 1400 1410 1420 1400 1410 1420 1430 pF1KB0 SPAAFTVGSNGKNVFSSSGTSFSGRKIKTAVRRRK ::::::::::::::::::::::::::::::::::: XP_005 SPAAFTVGSNGKNVFSSSGTSFSGRKIKTAVRRRK 1430 1440 1450 >>NP_005115 (OMIM: 603948) nuclear pore complex protein (1475 aa) initn: 5632 init1: 5632 opt: 5698 Z-score: 2982.7 bits: 564.5 E(85289): 2.1e-159 Smith-Waterman score: 9204; 97.1% identity (97.1% similar) in 1465 aa overlap (11-1433:11-1475) 10 20 30 40 50 60 pF1KB0 MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFN :::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 KNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTAS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 NYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 NYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 YGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 YGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 RESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPIT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 SSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL 490 500 510 520 530 540 550 560 570 pF1KB0 PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSS--------------------------- ::::::::::::::::::::::::::::::::: NP_005 PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPA 550 560 570 580 590 600 580 590 600 610 pF1KB0 ---------------GFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGS ::::::::::::::::::::::::::::::::::::::::::::: NP_005 EILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGS 610 620 630 640 650 660 620 630 640 650 660 670 pF1KB0 SWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFK 670 680 690 700 710 720 680 690 700 710 720 730 pF1KB0 PVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVT 730 740 750 760 770 780 740 750 760 770 780 790 pF1KB0 TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSG 790 800 810 820 830 840 800 810 820 830 840 850 pF1KB0 GSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAAS 850 860 870 880 890 900 860 870 880 890 900 910 pF1KB0 SSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFK 910 920 930 940 950 960 920 930 940 950 960 970 pF1KB0 FGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 FGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSA 970 980 990 1000 1010 1020 980 990 1000 1010 1020 1030 pF1KB0 GFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKG 1030 1040 1050 1060 1070 1080 1040 1050 1060 1070 1080 1090 pF1KB0 GFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQ 1090 1100 1110 1120 1130 1140 1100 1110 1120 1130 1140 1150 pF1KB0 TKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSS 1150 1160 1170 1180 1190 1200 1160 1170 1180 1190 1200 1210 pF1KB0 STPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 STPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKL 1210 1220 1230 1240 1250 1260 1220 1230 1240 1250 1260 1270 pF1KB0 ATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFG 1270 1280 1290 1300 1310 1320 1280 1290 1300 1310 1320 1330 pF1KB0 ANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1330 1340 1350 1360 1370 1380 1340 1350 1360 1370 1380 1390 pF1KB0 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1390 1400 1410 1420 1430 1440 1400 1410 1420 1430 pF1KB0 SPAAFTVGSNGKNVFSSSGTSFSGRKIKTAVRRRK ::::::::::::::::::::::::::::::::::: NP_005 SPAAFTVGSNGKNVFSSSGTSFSGRKIKTAVRRRK 1450 1460 1470 >>NP_001265138 (OMIM: 603948) nuclear pore complex prote (1506 aa) initn: 8721 init1: 5632 opt: 5698 Z-score: 2982.6 bits: 564.5 E(85289): 2.2e-159 Smith-Waterman score: 8903; 95.0% identity (95.0% similar) in 1465 aa overlap (42-1433:42-1506) 20 30 40 50 60 70 pF1KB0 GGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFNKNEDVCSCSTD :::::::::::::::::::::::::::::: NP_001 GGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFNKNEDVCSCSTD 20 30 40 50 60 70 80 90 100 110 120 130 pF1KB0 TSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSL 80 90 100 110 120 130 140 150 160 170 180 190 pF1KB0 HRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRA 140 150 160 170 180 190 200 210 220 230 240 250 pF1KB0 SDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGNSSILKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGNSSILKT 200 210 220 230 240 250 260 270 280 290 300 310 pF1KB0 SQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRI 260 270 280 290 300 310 320 330 340 350 360 370 pF1KB0 LQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPK 320 330 340 350 360 370 380 390 400 410 420 430 pF1KB0 PVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFS 380 390 400 410 420 430 440 450 460 pF1KB0 LPAANGLSSGVGGGGGKMRRERTRFVASKPLEEE-------------------------- :::::::::::::::::::::::::::::::::: NP_001 LPAANGLSSGVGGGGGKMRRERTRFVASKPLEEERQGLTVLPKLISSSCAQAIIPSWPLK 440 450 460 470 480 490 470 480 490 500 510 520 pF1KB0 -----EMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSST ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLRLQEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSST 500 510 520 530 540 550 530 540 550 560 570 pF1KB0 GSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSS------- ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTV 560 570 580 590 600 610 580 590 pF1KB0 -----------------------------------GFASPKIDSVAAQPTATSPVVYTRP ::::::::::::::::::::::::: NP_001 NSTNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRP 620 630 640 650 660 670 600 610 620 630 640 650 pF1KB0 AISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETP 680 690 700 710 720 730 660 670 680 690 700 710 pF1KB0 NKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTL 740 750 760 770 780 790 720 730 740 750 760 770 pF1KB0 TVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEK 800 810 820 830 840 850 780 790 800 810 820 830 pF1KB0 PGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPG 860 870 880 890 900 910 840 850 860 870 880 890 pF1KB0 TKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDS 920 930 940 950 960 970 900 910 920 930 940 950 pF1KB0 GSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQF 980 990 1000 1010 1020 1030 960 970 980 990 1000 1010 pF1KB0 GVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASV 1040 1050 1060 1070 1080 1090 1020 1030 1040 1050 1060 1070 pF1KB0 APFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGK 1100 1110 1120 1130 1140 1150 1080 1090 1100 1110 1120 1130 pF1KB0 KADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTT 1160 1170 1180 1190 1200 1210 1140 1150 1160 1170 1180 1190 pF1KB0 ADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAF 1220 1230 1240 1250 1260 1270 1200 1210 1220 1230 1240 1250 pF1KB0 GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSA 1280 1290 1300 1310 1320 1330 1260 1270 1280 1290 1300 1310 pF1KB0 GSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPP 1340 1350 1360 1370 1380 1390 1320 1330 1340 1350 1360 1370 pF1KB0 TFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGAN 1400 1410 1420 1430 1440 1450 1380 1390 1400 1410 1420 1430 pF1KB0 SSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFSGRKIKTAVRRRK ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFSGRKIKTAVRRRK 1460 1470 1480 1490 1500 >>XP_016867083 (OMIM: 603948) PREDICTED: nuclear pore co (1451 aa) initn: 7843 init1: 5632 opt: 5696 Z-score: 2981.8 bits: 564.3 E(85289): 2.4e-159 Smith-Waterman score: 9118; 96.3% identity (96.3% similar) in 1469 aa overlap (1-1433:1-1451) 10 20 30 40 50 60 pF1KB0 MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 KNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTAS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 NYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 YGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ :::::::::::::::::::::::::::::::::::::: :::: XP_016 YGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNS------------------VDSQ 310 320 330 340 370 380 390 400 410 420 pF1KB0 YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQ 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB0 RESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPIT 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB0 SSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL 470 480 490 500 510 520 550 560 570 pF1KB0 PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSS--------------------------- ::::::::::::::::::::::::::::::::: XP_016 PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSVNSTNCKKTPPEDCEGPFRPAEILKEG 530 540 550 560 570 580 580 590 600 610 620 pF1KB0 ---------GFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDT ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDT 590 600 610 620 630 640 630 640 650 660 670 680 pF1KB0 CLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTW 650 660 670 680 690 700 690 700 710 720 730 740 pF1KB0 DCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGF 710 720 730 740 750 760 750 760 770 780 790 800 pF1KB0 GDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLE 770 780 790 800 810 820 810 820 830 840 850 860 pF1KB0 KFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFG 830 840 850 860 870 880 870 880 890 900 910 920 pF1KB0 VSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSE 890 900 910 920 930 940 930 940 950 960 970 980 pF1KB0 SKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGT 950 960 970 980 990 1000 990 1000 1010 1020 1030 1040 pF1KB0 GVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGN 1010 1020 1030 1040 1050 1060 1050 1060 1070 1080 1090 1100 pF1KB0 VEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENS 1070 1080 1090 1100 1110 1120 1110 1120 1130 1140 1150 1160 pF1KB0 SKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATS 1130 1140 1150 1160 1170 1180 1170 1180 1190 1200 1210 1220 pF1KB0 AGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSST 1190 1200 1210 1220 1230 1240 1230 1240 1250 1260 1270 1280 pF1KB0 GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPT 1250 1260 1270 1280 1290 1300 1290 1300 1310 1320 1330 1340 pF1KB0 FGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSG 1310 1320 1330 1340 1350 1360 1350 1360 1370 1380 1390 1400 pF1KB0 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1370 1380 1390 1400 1410 1420 1410 1420 1430 pF1KB0 VGSNGKNVFSSSGTSFSGRKIKTAVRRRK ::::::::::::::::::::::::::::: XP_016 VGSNGKNVFSSSGTSFSGRKIKTAVRRRK 1430 1440 1450 >>XP_006715353 (OMIM: 603948) PREDICTED: nuclear pore co (1469 aa) initn: 5632 init1: 5632 opt: 5692 Z-score: 2979.6 bits: 563.9 E(85289): 3.2e-159 Smith-Waterman score: 9258; 97.5% identity (97.5% similar) in 1465 aa overlap (5-1433:5-1469) 10 20 30 40 50 60 pF1KB0 MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 KNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTAS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 NYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 YGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 RESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPIT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 SSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL 490 500 510 520 530 540 550 560 570 pF1KB0 PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSS--------------------------- ::::::::::::::::::::::::::::::::: XP_006 PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSVNSTNCKKTPPEDCEGPFRPAEILKEG 550 560 570 580 590 600 580 590 600 610 620 pF1KB0 ---------GFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDT ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDT 610 620 630 640 650 660 630 640 650 660 670 680 pF1KB0 CLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTW 670 680 690 700 710 720 690 700 710 720 730 740 pF1KB0 DCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGF 730 740 750 760 770 780 750 760 770 780 790 800 pF1KB0 GDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLE 790 800 810 820 830 840 810 820 830 840 850 860 pF1KB0 KFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFG 850 860 870 880 890 900 870 880 890 900 910 920 pF1KB0 VSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSE 910 920 930 940 950 960 930 940 950 960 970 980 pF1KB0 SKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGT 970 980 990 1000 1010 1020 990 1000 1010 1020 1030 1040 pF1KB0 GVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGN 1030 1040 1050 1060 1070 1080 1050 1060 1070 1080 1090 1100 pF1KB0 VEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENS 1090 1100 1110 1120 1130 1140 1110 1120 1130 1140 1150 1160 pF1KB0 SKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATS 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 1210 1220 pF1KB0 AGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSST 1210 1220 1230 1240 1250 1260 1230 1240 1250 1260 1270 1280 pF1KB0 GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPT 1270 1280 1290 1300 1310 1320 1290 1300 1310 1320 1330 1340 pF1KB0 FGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSG 1330 1340 1350 1360 1370 1380 1350 1360 1370 1380 1390 1400 pF1KB0 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1390 1400 1410 1420 1430 1440 1410 1420 1430 pF1KB0 VGSNGKNVFSSSGTSFSGRKIKTAVRRRK ::::::::::::::::::::::::::::: XP_006 VGSNGKNVFSSSGTSFSGRKIKTAVRRRK 1450 1460 >>XP_011513330 (OMIM: 603948) PREDICTED: nuclear pore co (1410 aa) initn: 7694 init1: 3776 opt: 4274 Z-score: 2241.8 bits: 427.3 E(85289): 4e-118 Smith-Waterman score: 8690; 92.7% identity (92.7% similar) in 1475 aa overlap (1-1433:1-1410) 10 20 30 40 50 60 pF1KB0 MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 KNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTAS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 NYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 YGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 RESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPIT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 SSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL 490 500 510 520 530 540 550 560 570 pF1KB0 PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSS--------------------------- ::::::::::::::::::::::::::::::::: XP_011 PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPA 550 560 570 580 590 600 580 590 600 610 pF1KB0 ---------------GFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGS ::::::::::::::::::::::::::::::::::::::::::::: XP_011 EILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGS 610 620 630 640 650 660 620 630 640 650 660 670 pF1KB0 SWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFK 670 680 690 700 710 720 680 690 700 710 720 730 pF1KB0 PVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVT 730 740 750 760 770 780 740 750 760 770 780 790 pF1KB0 TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSG :::::::::::::::::::::::::::::::::::::::::: XP_011 TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPG------------------ 790 800 810 820 800 810 820 830 840 850 pF1KB0 GSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAAS ::::::::::::: XP_011 -----------------------------------------------FDTSSSSSNSAAS 830 860 870 880 890 900 910 pF1KB0 SSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFK 840 850 860 870 880 890 920 930 940 950 960 970 pF1KB0 FGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSA 900 910 920 930 940 950 980 990 1000 1010 1020 1030 pF1KB0 GFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKG 960 970 980 990 1000 1010 1040 1050 1060 1070 1080 1090 pF1KB0 GFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQ 1020 1030 1040 1050 1060 1070 1100 1110 1120 1130 1140 1150 pF1KB0 TKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSS 1080 1090 1100 1110 1120 1130 1160 1170 1180 1190 1200 1210 pF1KB0 STPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKL 1140 1150 1160 1170 1180 1190 1220 1230 1240 1250 1260 1270 pF1KB0 ATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFG 1200 1210 1220 1230 1240 1250 1280 1290 1300 1310 1320 1330 pF1KB0 ANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1260 1270 1280 1290 1300 1310 1340 1350 1360 1370 1380 1390 pF1KB0 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1320 1330 1340 1350 1360 1370 1400 1410 1420 1430 pF1KB0 SPAAFTVGSNGKNVFSSSGTSFSGRKIKTAVRRRK ::::::::::::::::::::::::::::::::::: XP_011 SPAAFTVGSNGKNVFSSSGTSFSGRKIKTAVRRRK 1380 1390 1400 1410 >>XP_006715354 (OMIM: 603948) PREDICTED: nuclear pore co (839 aa) initn: 4164 init1: 3744 opt: 3752 Z-score: 1973.3 bits: 376.9 E(85289): 3.6e-103 Smith-Waterman score: 5062; 94.9% identity (94.9% similar) in 822 aa overlap (1-780:1-822) 10 20 30 40 50 60 pF1KB0 MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 KNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTAS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 NYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 YGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 RESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPIT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 SSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL 490 500 510 520 530 540 550 560 570 pF1KB0 PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSS--------------------------- ::::::::::::::::::::::::::::::::: XP_006 PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPA 550 560 570 580 590 600 580 590 600 610 pF1KB0 ---------------GFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGS ::::::::::::::::::::::::::::::::::::::::::::: XP_006 EILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGS 610 620 630 640 650 660 620 630 640 650 660 670 pF1KB0 SWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFK 670 680 690 700 710 720 680 690 700 710 720 730 pF1KB0 PVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVT 730 740 750 760 770 780 740 750 760 770 780 790 pF1KB0 TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSG :::::::::::::::::::::::::::::::::::::::::: XP_006 TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGCHLVMVPLCFYFPPLRP 790 800 810 820 830 800 810 820 830 840 850 pF1KB0 GSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAAS >>XP_011509878 (OMIM: 601181,608033) PREDICTED: E3 SUMO- (3199 aa) initn: 746 init1: 197 opt: 541 Z-score: 293.6 bits: 68.0 E(85289): 1.3e-09 Smith-Waterman score: 665; 32.4% identity (58.6% similar) in 488 aa overlap (597-1041:1466-1913) 570 580 590 600 610 620 pF1KB0 EPIISSSGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCL .: :.: : : : : :. :.:..:: XP_011 IACQNTKSANKSGSSFVHQASFKFGQGDLPKPINSDFRSV---F--STKEGQ-WDCSACL 1440 1450 1460 1470 1480 630 640 650 660 670 680 pF1KB0 LQNKVTDNKCIACQAAKLSPR-DTAKQTGIETPN--KSGKTTLSAS-GTGFGDKFKPVIG .::. ...:: ::: .:: .. :.: :: : : . : . .:: : : : XP_011 VQNEGSSTKCAACQ----NPRKQSLPATSIPTPASFKFGTSETSKTLKSGFEDMFAKKEG 1490 1500 1510 1520 1530 1540 690 700 710 720 730 740 pF1KB0 TWDCDTCLVQNKPEAIKCVACETP-KPGTCVKRALTLTVVSESAETMTASSSSCTVTTGT :::..:::.:. .: .::::..: ::. .. . ..:: : .: XP_011 QWDCSSCLVRNEANATRCVACQNPDKPSPSTSVPAPASFKFGTSETSKAPKS-------- 1550 1560 1570 1580 1590 750 760 770 780 790 pF1KB0 LGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVS-----LP :: : . :.:.:::: : :.: .::..: ..::.. ..:. ..:.: : XP_011 -GFEGMFTKKEGQWDCSVCLVRNEASATKCIAC--QNPGKQNQTTSAVSTPASSETSKAP 1600 1610 1620 1630 1640 1650 800 810 820 830 pF1KB0 SGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACES----------AKPGT------- ..: :. : : ::.::: .:::.:.:..:::.::. . :.. XP_011 KSGFEGM--FTKKEGQWDCSVCLVRNEASATKCIACQCPSKQNQTTAISTPASSEISKAP 1660 1670 1680 1690 1700 1710 840 850 860 870 880 pF1KB0 KSGFKG-------FDTSSSSSNSAASSSFKFGVSSSSSGPSQ--------TLTSTGNFKF ::::.: .: : .. :::.: :. ..: :.. ..: ...:. XP_011 KSGFEGMFIRKGQWDCSVCCVQNE-SSSLKC-VACDASKPTHKPIAEAPSAFTLGSEMKL 1720 1730 1740 1750 1760 1770 890 900 910 920 930 940 pF1KB0 GDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFG-VSSESKPEEVKKDSKNDNFKFGL :..: ..:.. : : .. ::.. :::: :..:..: . . :.: .:: . XP_011 HDSSGSQVGTGFKS---NFSEKASKFGNTEQGFKFGHVDQENSPSFMFQGSSNTEFK-ST 1780 1790 1800 1810 1820 950 960 970 980 990 1000 pF1KB0 SSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENK . :.: ::: :.::.:. :..::: : : ...::. . . : . .. .... XP_011 KEGFSIPVSADGFKFGISEPGNQEKKSEKPLENGTGFQ-AQDI--SGQKNGRGVIFGQTS 1830 1840 1850 1860 1870 1880 1010 1020 1030 1040 1050 1060 pF1KB0 SSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEE :.:... . .::.: : .::. : :: :: XP_011 STFTFADL-AKSTSGEGFQF----GKKD--PNFKG-FSGAGEKLFSSQYGKMANKANTSG 1890 1900 1910 1920 1930 1070 1080 1090 1100 1110 1120 pF1KB0 KQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQ XP_011 DFEKDDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEDEKVLYSQRVKLFRFDAEVSQWKE 1940 1950 1960 1970 1980 1990 >>XP_016860112 (OMIM: 601181,608033) PREDICTED: E3 SUMO- (2807 aa) initn: 772 init1: 197 opt: 538 Z-score: 292.9 bits: 67.7 E(85289): 1.4e-09 Smith-Waterman score: 672; 26.4% identity (54.7% similar) in 793 aa overlap (310-1041:1231-1972) 280 290 300 310 320 330 pF1KB0 NTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSP :.:. :.. . :. :.. .: :. XP_016 LFRFDVESKEWKERGIGNVKILRHKTSGKIRLLMRREQVLKICANHYISPDMKLTP-NAG 1210 1220 1230 1240 1250 340 350 360 370 380 390 pF1KB0 LDRS----GIDITDFQAKREKVDSQYPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRK ::: ..: .: : :.. . :. ::. ... . . : : XP_016 SDRSFVWHALDYADELPKPEQL------AIRFKTPEEAALFKCKFEEAQSILKAPG---- 1260 1270 1280 1290 1300 400 410 420 430 440 450 pF1KB0 TNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMRRERT- :: . .. .. :. : .:.. .: . :: . .:. .: .. ... : XP_016 TNVAMASNQAVRIVKEPTSHDNKDICKSDAGNLNFEFQVAKKEGSWWHCNSCSLKNASTA 1310 1320 1330 1340 1350 1360 460 470 480 490 500 pF1KB0 -RFVASKPLEEEEMEV---PVLPKISLPITS--SSLPTFNFSSPEIT---TSSPSPINSS . :. . :. . :. :. . : :: . : . .:. : . . XP_016 KKCVSCQNLNPSNKELVGPPLAETVFTPKTSPENVQDRFALVTPKKEGHWDCSICLVRNE 1370 1380 1390 1400 1410 1420 510 520 530 540 550 560 pF1KB0 QALTNKV--QMT-SPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELSGS ... . : : : ...:: . . .: : .... : . : :: .: .. . : XP_016 PTVSRCIACQNTKSANKSGSSFVHQAS--FKFGQGDLPKPINSDFR-SVFSTKEGQWDCS 1430 1440 1450 1460 1470 1480 570 580 590 600 610 pF1KB0 SSTLEPIISSSGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGI--GFGESL-KAGSS . .. ::. :. . . :... :. . .: .:. . :: . . : .. XP_016 ACLVQNEGSSTKCAACQNPRKQSLPATSIPTPASFKFGTSETSKTLKSGFEDMFAKKEGQ 1490 1500 1510 1520 1530 1540 620 630 640 650 660 670 pF1KB0 WQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPN--KSGKTTLS-ASGTGFGDK :.:..::..:... ..:.::: .: . .:.. .: : : . : : .:: XP_016 WDCSSCLVRNEANATRCVACQ----NPDKPSPSTSVPAPASFKFGTSETSKAPKSGFEGM 1550 1560 1570 1580 1590 1600 680 690 700 710 720 730 pF1KB0 FKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCT : : :::..:::.:. : ::.::..: : :. : ..:: : . :... . XP_016 FTKKEGQWDCSVCLVRNEASATKCIACQNP--G---KQNQTTSAVSTPASSETSKAPKS- 1610 1620 1630 1640 1650 740 750 760 770 780 790 pF1KB0 VTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVS-- :: : . :.:.:::: : :.: .::..: ..::.. ..:. ..:.: XP_016 ------GFEGMFTKKEGQWDCSVCLVRNEASATKCIAC--QNPGKQNQTTSAVSTPASSE 1660 1670 1680 1690 1700 800 810 820 830 pF1KB0 ---LPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACES----------AKPGT-- :..: :. : : ::.::: .:::.:.:..:::.::. . :.. XP_016 TSKAPKSGFEGM--FTKKEGQWDCSVCLVRNEASATKCIACQCPSKQNQTTAISTPASSE 1710 1720 1730 1740 1750 1760 840 850 860 870 pF1KB0 -----KSGFKG-------FDTSSSSSNSAASSSFKFGVSSSSSGPSQ--------TLTST ::::.: .: : .. :::.: :. ..: :.. ..: XP_016 ISKAPKSGFEGMFIRKGQWDCSVCCVQNE-SSSLKC-VACDASKPTHKPIAEAPSAFTLG 1770 1780 1790 1800 1810 1820 880 890 900 910 920 930 pF1KB0 GNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFG-VSSESKPEEVKKDSKNDN ...:. :..: ..:.. : : .. ::.. :::: :..:..: . . :.: . XP_016 SEMKLHDSSGSQVGTGFKS---NFSEKASKFGNTEQGFKFGHVDQENSPSFMFQGSSNTE 1830 1840 1850 1860 1870 1880 940 950 960 970 980 990 pF1KB0 FKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIV :: . . :.: ::: :.::.:. :..::: : : ...::. . . : . .. XP_016 FK-STKEGFSIPVSADGFKFGISEPGNQEKKSEKPLENGTGFQ-AQDI--SGQKNGRGVI 1890 1900 1910 1920 1930 1000 1010 1020 1030 1040 1050 pF1KB0 TSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVL ....:.:... . .::.: : .::. : :: :: XP_016 FGQTSSTFTFADL-AKSTSGEGFQF----GKKD--PNFKG-FSGAGEKLFSSQYGKMANK 1940 1950 1960 1970 1980 1060 1070 1080 1090 1100 1110 pF1KB0 GRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSE XP_016 ANTSGDFEKDDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEDEKVLYSQRVKLFRFDAEV 1990 2000 2010 2020 2030 2040 1433 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 22:33:29 2016 done: Wed Nov 2 22:33:32 2016 Total Scan time: 19.800 Total Display time: 0.610 Function used was FASTA [36.3.4 Apr, 2011]