Result of FASTA (omim) for
pF1KB0049
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0049, 1823 aa
1>>>pF1KB0049 1823 - 1823 aa - 1823 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.7673+/-0.000714; mu= 8.1843+/- 0.043
mean_var=321.3117+/-64.006, 0's: 0 Z-trim(111.1): 331 B-trim: 156 in 3/53
Lambda= 0.071550
statistics sampled from 19290 (19627) to 19290 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.566), E-opt: 0.2 (0.23), width: 16
Scan time: 19.080
The best scores are: opt bits E(85289)
XP_005267041 (OMIM: 600133,615235) PREDICTED: lami (1823) 12143 1270.4 0
XP_005267040 (OMIM: 600133,615235) PREDICTED: lami (1823) 12143 1270.4 0
NP_001098676 (OMIM: 600133,615235) laminin subunit (1823) 12143 1270.4 0
NP_002281 (OMIM: 600133,615235) laminin subunit al (1816) 12066 1262.5 0
NP_001098677 (OMIM: 600133,615235) laminin subunit (1816) 12066 1262.5 0
XP_016866343 (OMIM: 600133,615235) PREDICTED: lami (1816) 12066 1262.5 0
NP_001121190 (OMIM: 226650,226700,245660,600805) l (1668) 948 114.8 7.2e-24
NP_000218 (OMIM: 226650,226700,245660,600805) lami (1724) 948 114.8 7.4e-24
XP_016881233 (OMIM: 226650,226700,245660,600805) P (1856) 948 114.8 7.7e-24
XP_016881232 (OMIM: 226650,226700,245660,600805) P (2626) 948 115.0 9.6e-24
XP_011524284 (OMIM: 226650,226700,245660,600805) P (3243) 948 115.1 1.1e-23
NP_001121189 (OMIM: 226650,226700,245660,600805) l (3277) 948 115.1 1.1e-23
XP_011524283 (OMIM: 226650,226700,245660,600805) P (3298) 948 115.2 1.1e-23
NP_937762 (OMIM: 226650,226700,245660,600805) lami (3333) 948 115.2 1.1e-23
XP_011524282 (OMIM: 226650,226700,245660,600805) P (3336) 948 115.2 1.1e-23
XP_011524281 (OMIM: 226650,226700,245660,600805) P (3339) 948 115.2 1.1e-23
XP_011524280 (OMIM: 226650,226700,245660,600805) P (3342) 948 115.2 1.1e-23
XP_006723861 (OMIM: 601033) PREDICTED: laminin sub (2300) 850 104.8 9.8e-21
XP_011527121 (OMIM: 601033) PREDICTED: laminin sub (3609) 850 105.1 1.3e-20
XP_011527120 (OMIM: 601033) PREDICTED: laminin sub (3654) 850 105.1 1.3e-20
NP_005551 (OMIM: 601033) laminin subunit alpha-5 p (3695) 850 105.1 1.3e-20
XP_006723859 (OMIM: 601033) PREDICTED: laminin sub (3700) 850 105.1 1.3e-20
XP_011523958 (OMIM: 150320,615960) PREDICTED: lami (2561) 773 97.0 2.6e-18
XP_011523957 (OMIM: 150320,615960) PREDICTED: lami (3085) 773 97.1 2.9e-18
XP_011523959 (OMIM: 150320,615960) PREDICTED: lami (2489) 729 92.4 5.9e-17
XP_016866342 (OMIM: 156225,607855) PREDICTED: lami (1916) 624 81.4 9.2e-14
XP_016866341 (OMIM: 156225,607855) PREDICTED: lami (2587) 624 81.6 1.1e-13
XP_005267039 (OMIM: 156225,607855) PREDICTED: lami (3206) 624 81.7 1.3e-13
XP_011534122 (OMIM: 156225,607855) PREDICTED: lami (3208) 624 81.7 1.3e-13
XP_005267038 (OMIM: 156225,607855) PREDICTED: lami (3210) 624 81.7 1.3e-13
XP_016866340 (OMIM: 156225,607855) PREDICTED: lami (3212) 624 81.7 1.3e-13
NP_001073291 (OMIM: 156225,607855) laminin subunit (3118) 622 81.5 1.4e-13
NP_000417 (OMIM: 156225,607855) laminin subunit al (3122) 622 81.5 1.4e-13
XP_016867691 (OMIM: 150240,615191) PREDICTED: lami (1212) 610 79.7 1.9e-13
NP_002282 (OMIM: 150240,615191) laminin subunit be (1786) 610 79.9 2.4e-13
XP_016867690 (OMIM: 150240,615191) PREDICTED: lami (1810) 610 79.9 2.4e-13
NP_001304976 (OMIM: 616380) laminin subunit beta-4 (1101) 605 79.2 2.5e-13
XP_011514282 (OMIM: 616380) PREDICTED: laminin sub (1564) 605 79.3 3.2e-13
XP_016867369 (OMIM: 616380) PREDICTED: laminin sub (1567) 605 79.3 3.2e-13
XP_011514281 (OMIM: 616380) PREDICTED: laminin sub (1703) 605 79.4 3.3e-13
XP_011514280 (OMIM: 616380) PREDICTED: laminin sub (1723) 605 79.4 3.4e-13
XP_016867368 (OMIM: 616380) PREDICTED: laminin sub (1753) 605 79.4 3.4e-13
NP_001304975 (OMIM: 616380) laminin subunit beta-4 (1761) 605 79.4 3.4e-13
NP_031382 (OMIM: 616380) laminin subunit beta-4 is (1761) 605 79.4 3.4e-13
XP_011514277 (OMIM: 616380) PREDICTED: laminin sub (1772) 605 79.4 3.4e-13
XP_005265184 (OMIM: 150325,609049,614199) PREDICTE (1798) 600 78.9 4.9e-13
NP_002283 (OMIM: 150325,609049,614199) laminin sub (1798) 600 78.9 4.9e-13
NP_002284 (OMIM: 150290) laminin subunit gamma-1 p (1609) 583 77.1 1.6e-12
XP_006716984 (OMIM: 604349,614115) PREDICTED: lami (1259) 545 73.0 2e-11
NP_006050 (OMIM: 604349,614115) laminin subunit ga (1575) 545 73.2 2.3e-11
>>XP_005267041 (OMIM: 600133,615235) PREDICTED: laminin (1823 aa)
initn: 12143 init1: 12143 opt: 12143 Z-score: 6794.4 bits: 1270.4 E(85289): 0
Smith-Waterman score: 12143; 100.0% identity (100.0% similar) in 1823 aa overlap (1-1823:1-1823)
10 20 30 40 50 60
pF1KB0 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 CNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDDLRLAALSIEEGKSGVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDDLRLAALSIEEGKSGVLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB0 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB0 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB0 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB0 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KB0 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KB0 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG
1750 1760 1770 1780 1790 1800
1810 1820
pF1KB0 HPVSFSKAALVSGAVSINSCPAA
:::::::::::::::::::::::
XP_005 HPVSFSKAALVSGAVSINSCPAA
1810 1820
>>XP_005267040 (OMIM: 600133,615235) PREDICTED: laminin (1823 aa)
initn: 12143 init1: 12143 opt: 12143 Z-score: 6794.4 bits: 1270.4 E(85289): 0
Smith-Waterman score: 12143; 100.0% identity (100.0% similar) in 1823 aa overlap (1-1823:1-1823)
10 20 30 40 50 60
pF1KB0 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 CNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDDLRLAALSIEEGKSGVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDDLRLAALSIEEGKSGVLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB0 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB0 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB0 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB0 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KB0 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KB0 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG
1750 1760 1770 1780 1790 1800
1810 1820
pF1KB0 HPVSFSKAALVSGAVSINSCPAA
:::::::::::::::::::::::
XP_005 HPVSFSKAALVSGAVSINSCPAA
1810 1820
>>NP_001098676 (OMIM: 600133,615235) laminin subunit alp (1823 aa)
initn: 12143 init1: 12143 opt: 12143 Z-score: 6794.4 bits: 1270.4 E(85289): 0
Smith-Waterman score: 12143; 100.0% identity (100.0% similar) in 1823 aa overlap (1-1823:1-1823)
10 20 30 40 50 60
pF1KB0 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 CNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDDLRLAALSIEEGKSGVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDDLRLAALSIEEGKSGVLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB0 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB0 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB0 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB0 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KB0 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KB0 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG
1750 1760 1770 1780 1790 1800
1810 1820
pF1KB0 HPVSFSKAALVSGAVSINSCPAA
:::::::::::::::::::::::
NP_001 HPVSFSKAALVSGAVSINSCPAA
1810 1820
>>NP_002281 (OMIM: 600133,615235) laminin subunit alpha- (1816 aa)
initn: 10089 init1: 10089 opt: 12066 Z-score: 6751.5 bits: 1262.5 E(85289): 0
Smith-Waterman score: 12066; 99.6% identity (99.6% similar) in 1823 aa overlap (1-1823:1-1816)
10 20 30 40 50 60
pF1KB0 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 CNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDDLRLAALSIEEGKSGVLS
::::::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_002 CNCGGGPCDSVTGECLEEGFEPPTG-------CDKCVWDLTDDLRLAALSIEEGKSGVLS
250 260 270 280 290
310 320 330 340 350 360
pF1KB0 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB0 NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB0 VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB0 YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB0 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB0 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB0 QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB0 AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB0 ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB0 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB0 NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB0 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB0 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KB0 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KB0 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KB0 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KB0 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KB0 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KB0 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KB0 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KB0 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR
1500 1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KB0 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN
1560 1570 1580 1590 1600 1610
1630 1640 1650 1660 1670 1680
pF1KB0 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS
1620 1630 1640 1650 1660 1670
1690 1700 1710 1720 1730 1740
pF1KB0 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS
1680 1690 1700 1710 1720 1730
1750 1760 1770 1780 1790 1800
pF1KB0 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG
1740 1750 1760 1770 1780 1790
1810 1820
pF1KB0 HPVSFSKAALVSGAVSINSCPAA
:::::::::::::::::::::::
NP_002 HPVSFSKAALVSGAVSINSCPAA
1800 1810
>>NP_001098677 (OMIM: 600133,615235) laminin subunit alp (1816 aa)
initn: 10089 init1: 10089 opt: 12066 Z-score: 6751.5 bits: 1262.5 E(85289): 0
Smith-Waterman score: 12066; 99.6% identity (99.6% similar) in 1823 aa overlap (1-1823:1-1816)
10 20 30 40 50 60
pF1KB0 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 CNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDDLRLAALSIEEGKSGVLS
::::::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_001 CNCGGGPCDSVTGECLEEGFEPPTG-------CDKCVWDLTDDLRLAALSIEEGKSGVLS
250 260 270 280 290
310 320 330 340 350 360
pF1KB0 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB0 NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB0 VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB0 YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB0 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB0 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB0 QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB0 AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB0 ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB0 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB0 NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB0 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB0 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KB0 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KB0 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KB0 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KB0 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KB0 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KB0 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KB0 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KB0 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR
1500 1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KB0 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN
1560 1570 1580 1590 1600 1610
1630 1640 1650 1660 1670 1680
pF1KB0 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS
1620 1630 1640 1650 1660 1670
1690 1700 1710 1720 1730 1740
pF1KB0 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS
1680 1690 1700 1710 1720 1730
1750 1760 1770 1780 1790 1800
pF1KB0 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG
1740 1750 1760 1770 1780 1790
1810 1820
pF1KB0 HPVSFSKAALVSGAVSINSCPAA
:::::::::::::::::::::::
NP_001 HPVSFSKAALVSGAVSINSCPAA
1800 1810
>>XP_016866343 (OMIM: 600133,615235) PREDICTED: laminin (1816 aa)
initn: 10089 init1: 10089 opt: 12066 Z-score: 6751.5 bits: 1262.5 E(85289): 0
Smith-Waterman score: 12066; 99.6% identity (99.6% similar) in 1823 aa overlap (1-1823:1-1816)
10 20 30 40 50 60
pF1KB0 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 CNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDDLRLAALSIEEGKSGVLS
::::::::::::::::::::::::: ::::::::::::::::::::::::::::
XP_016 CNCGGGPCDSVTGECLEEGFEPPTG-------CDKCVWDLTDDLRLAALSIEEGKSGVLS
250 260 270 280 290
310 320 330 340 350 360
pF1KB0 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB0 NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB0 VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB0 YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB0 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB0 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB0 QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB0 AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB0 ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB0 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB0 NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB0 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB0 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KB0 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KB0 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KB0 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KB0 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KB0 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KB0 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KB0 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KB0 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR
1500 1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KB0 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN
1560 1570 1580 1590 1600 1610
1630 1640 1650 1660 1670 1680
pF1KB0 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS
1620 1630 1640 1650 1660 1670
1690 1700 1710 1720 1730 1740
pF1KB0 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS
1680 1690 1700 1710 1720 1730
1750 1760 1770 1780 1790 1800
pF1KB0 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG
1740 1750 1760 1770 1780 1790
1810 1820
pF1KB0 HPVSFSKAALVSGAVSINSCPAA
:::::::::::::::::::::::
XP_016 HPVSFSKAALVSGAVSINSCPAA
1800 1810
>>NP_001121190 (OMIM: 226650,226700,245660,600805) lamin (1668 aa)
initn: 1864 init1: 610 opt: 948 Z-score: 549.5 bits: 114.8 E(85289): 7.2e-24
Smith-Waterman score: 2849; 31.2% identity (62.8% similar) in 1797 aa overlap (47-1821:40-1666)
20 30 40 50 60 70
pF1KB0 WSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHT--
:: :. ... .. :. . :. :...
NP_001 CSMGWLWIFGAALGQCLGYSSQQQRVPFLQPPGQSQLQASYVEFRPS-QGCSPGYYRDHK
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB0 --LSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPC
.:.::::.:::.::.: :::: ::.::.::.:::::.: .:: :....:. :. :
NP_001 GLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGS---CRAC
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB0 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGN
::: : .:: .: ..: ::: :. .:.: .::::::::.::: .:..:. :.:..:
NP_001 PCP--HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSN
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB0 SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVT
.. . .: .::.: : : ::
NP_001 GQ----LGSCHPLTGDCIN---------------------------------QEPKDSSP
190 200
260 270 280 290 300 310
pF1KB0 GECLEEGFEPPTGMDCPTISCDKCVWDLTDDLRLAALSIEEGKSGVLSVSSGAAAHRHVN
.: .: .::.:: : .:: . ... :: . ..:..:. ...
NP_001 AE------------ECD--DCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMR
210 220 230 240 250
320 330 340 350 360 370
pF1KB0 EINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKGQLVQK
.... :...: . .. . . .:.. : . .: .. : : :: . :::.: ..
NP_001 HMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLN-
260 270 280 290 300 310
380 390 400 410 420 430
pF1KB0 ESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKMLEEIRS
...:.:.: .:... ::... .. : ::..::.
NP_001 ---NNVNRATQ---SAKELDVKIKNVIRNV------H----------------MLNRIRT
320 330 340
440 450 460 470 480 490
pF1KB0 RQPFFTQRELVDEEADEAYELLSQAESWQRLHN-ETRTLFPVVLEQLDDYNAKLSDLQEA
::. :. :. : . ..:..:.::::::.
NP_001 ---------------------------WQKTHQGENNGLANSIRDSLNEYEAKLSDLRAR
350 360 370
500 510 520 530 540
pF1KB0 LDQALNYVRDAEDMN----RATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLT
:..: ...:. .: :: .: :: : ... . . :.:. .:: ..
NP_001 LQEAAAQAKQANGLNQENERALGAIQR----QVKEINSLQSDFTKYLTTADSSLLQTNIA
380 390 400 410 420 430
550 560 570 580 590 600
pF1KB0 LSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSH--DLVQEAIDHAQDLQQEANELS
:. .. :. . : .. :..::. :. .:: . .::.:: ::..::. :..:
NP_001 LQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLE
440 450 460 470 480 490
610 620 630 640 650 660
pF1KB0 RKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT--QII
. .... . ::. :.::...::::.: .. :...:. : .... ..: : .
NP_001 EIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAK
500 510 520 530 540 550
670 680 690 700 710 720
pF1KB0 YHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAE
...:..:::.:. : : .. . :. . .. .. . ..: .. : :. :.. .
NP_001 TLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQ
560 570 580 590 600 610
730 740 750 760 770 780
pF1KB0 RGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARD
::: . ..... ....:: : :: .. :. ... ... . .. .. :...: .
NP_001 RGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADN
620 630 640 650 660 670
790 800 810 820 830 840
pF1KB0 AVRNLTEVVPQLLDQLRTVEQKR-PASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQS
.: .::. .:.: ......:. : .:.: ...:::::: :.:..:::. : : :.:.:
NP_001 SVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKVAVPMRFNGKS
680 690 700 710 720 730
850 860 870 880 890 900
pF1KB0 AVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKND
.:::. ....:::..:::::... : .: : : ..:..:::.:.:...:.:.:. .
NP_001 GVEVRLPNDLEDLKGYTSLSLFLQRPNSR-ENGGTENMFVMYLGNKDASRDYIGMAVVDG
740 750 760 770 780 790
910 920 930 940 950 960
pF1KB0 NLVYVYNLGTKDVEIPLDSKPVSSWP--AYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF
.:. ::::: ...:. .:. ..: : .. ::..:. . ... : . :: :
NP_001 QLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPG
800 810 820 830 840 850
970 980 990 1000 1010 1020
pF1KB0 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN
. . ....::.::::..:::::: : .::::. :..: . ::.:: ::..:.::::
NP_001 VYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYN
860 870 880 890 900 910
1030 1040 1050 1060 1070 1080
pF1KB0 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR
::. .:.. . :: : : .. . .:.:.::: : . . : ..
NP_001 FKKTFNLNTTEVEPCRRRK-----EESDKNYFEGTGYARV----PTQPHAPIPTFGQTIQ
920 930 940 950 960
1090 1100 1110 1120 1130 1140
pF1KB0 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS
: .: ::... ::. :. :....: : : : .. : : : . : ::... : :.
NP_001 TTVDRGLLFFAENGDRFISLNIEDGKLMVRYKLN-SELPK--ERGVGDA-INNGRDHSIQ
970 980 990 1000 1010
1150 1160 1170 1180 1190
pF1KB0 I-IYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFR
: : . .:.: . :: ... .:.: . :. :.:: : : . . : ::
NP_001 IKIGKLQKRMWINVDVQNTI-IDGEVF--DFSTYYLGGIPIAIRER--FNISTP---AFR
1020 1030 1040 1050 1060 1070
1200 1210 1220 1230 1240 1250
pF1KB0 GCMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFN-GQSFIASIQKISFFDGFE
::::.. :: .... ..:.:: : :: . : : :. : .. . . : ..
NP_001 GCMKNL---KKTSGVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQ
1080 1090 1100 1110 1120
1260 1270 1280 1290 1300 1310
pF1KB0 GGFNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVK--GIKVQSVDKQYNDGLSHFV-
..:.:.:.::.:.:. . . . ....:..: . .... : . . . : ::: :.:
NP_001 ASFGFQTFQPSGILLDHQTWTRNLQVTLEDGYIELSTSDSGGPIFKSPQTYMDGLLHYVS
1130 1140 1150 1160 1170 1180
1320 1330 1340 1350 1360 1370
pF1KB0 -ISSVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNA
::. : : :: :. .:: .... ..:.... .::: :: :::::.
NP_001 VISDNSGLRL-LIDDQLLRNSK-----RLKHISSSRQSLRLGGS-------NFEGCISNV
1190 1200 1210 1220 1230
1380 1390 1400 1410 1420 1430
pF1KB0 YFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSK
. :.. . :: :. . : .:: : ... :...: : . ..: :. . .. .
NP_001 FVQRLSLSPEVLDLTSNSLKRDVSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQ--LLQ
1240 1250 1260 1270 1280 1290
1440 1450 1460 1470 1480 1490
pF1KB0 DAPSWDPVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQ
:.: .: ..:. . . : . .: . : :.: .:. :. . . .::
NP_001 DTPVASPRSVKVWQ------DACSPLPKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQ
1300 1310 1320 1330 1340
1500 1510 1520 1530 1540 1550
pF1KB0 FSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWH
:.. ..: ::.:..:... . :.::.:.:..::::. ... :::.:.:.:: ::: ::
NP_001 FAVDMQTTSSRGLVFHTGTK--NSFMALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWH
1350 1360 1370 1380 1390 1400
1560 1570 1580 1590 1600 1610
pF1KB0 DVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSF
:.: .. .::::.::::. : ::: . .: .:..:.:::. :: :.. : ::
NP_001 TVVFGHDGEKGRLVVDGLRAREGSLPGN-STISIRAPVYLGSPPSGKP-KSLPTN---SF
1410 1420 1430 1440 1450
1620 1630 1640 1650 1660 1670
pF1KB0 SGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAF
:::.:.::.. . . :..:.:. :. ::.: : ::: :::.::: .: .: .:...:
NP_001 VGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVF
1460 1470 1480 1490 1500 1510
1680 1690 1700 1710 1720 1730
pF1KB0 EVRPRSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRI
.:::: .: :.: : :..: :... :.: .....: :::::::::::::.:: .
NP_001 SIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSV
1520 1530 1540 1550 1560 1570
1740 1750 1760 1770 1780 1790
pF1KB0 TVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIR
.: .....:..:.. ....: . : . .::. .::.: .: : :. : : ::.:
NP_001 AVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFFGCLR
1580 1590 1600 1610 1620 1630
1800 1810 1820
pF1KB0 HFVIDGHPVSFSKAALVSGAVSINSCPAA
.. .. :: ..: :.: ::.:.::
NP_001 NIHVNHIPVPVTEALEVQGPVSLNGCPDQ
1640 1650 1660
>>NP_000218 (OMIM: 226650,226700,245660,600805) laminin (1724 aa)
initn: 2033 init1: 610 opt: 948 Z-score: 549.3 bits: 114.8 E(85289): 7.4e-24
Smith-Waterman score: 2983; 31.8% identity (64.3% similar) in 1807 aa overlap (47-1821:40-1722)
20 30 40 50 60 70
pF1KB0 WSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHT--
:: :. ... .. :. . :. :...
NP_000 CSMGWLWIFGAALGQCLGYSSQQQRVPFLQPPGQSQLQASYVEFRPS-QGCSPGYYRDHK
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB0 --LSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPC
.:.::::.:::.::.: :::: ::.::.::.:::::.: .:: :....:. :. :
NP_000 GLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGS---CRAC
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB0 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGN
::: : .:: .: ..: ::: :. .:.: .::::::::.::: .:..:. :.:..:
NP_000 PCP--HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSN
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB0 SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVT
.. . .: .::.: : : ::
NP_000 GQ----LGSCHPLTGDCIN---------------------------------QEPKDSSP
190 200
260 270 280 290 300 310
pF1KB0 GECLEEGFEPPTGMDCPTISCDKCVWDLTDDLRLAALSIEEGKSGVLSVSSGAAAHRHVN
.: .: .::.:: : .:: . ... :: . ..:..:. ...
NP_000 AE------------ECD--DCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMR
210 220 230 240 250
320 330 340 350 360 370
pF1KB0 EINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKGQLVQK
.... :...: . .. . . .:.. : . .: .. : : :: . :::.: ..
NP_000 HMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLN-
260 270 280 290 300 310
380 390 400 410 420
pF1KB0 ESMDTINHASQLVEQAHDMRDKIQEI--NNKMLYY------GEEHELSPKEISEKLVLAQ
...:.:.: .:... ::... : ..: :: ... ..:.. . ::
NP_000 ---NNVNRATQ---SAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQ
320 330 340 350 360
430 440 450 460 470 480
pF1KB0 KMLEEIRSRQPFFTQRELVDEEAD--EAYELLSQAESWQRLHN-ETRTLFPVVLEQLDDY
.:..:.:.:. : ..: . ::: :. ::.. ..::. :. :. : . ..:..:
NP_000 RMMRELRNRN-F--GKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEY
370 380 390 400 410 420
490 500 510 520 530
pF1KB0 NAKLSDLQEALDQALNYVRDAEDMN----RATAARQRDHEKQQERVREQMEVVNMSLSTS
.::::::. :..: ...:. .: :: .: :: : ... . . :.:.
NP_000 EAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQR----QVKEINSLQSDFTKYLTTA
430 440 450 460 470
540 550 560 570 580 590
pF1KB0 ADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSH--DLVQEAIDHAQ
.:: ..:. .. :. . : .. :..::. :. .:: . .::.:: ::.
NP_000 DSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHAR
480 490 500 510 520 530
600 610 620 630 640 650
pF1KB0 DLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAV
.::. :..: . .... . ::. :.::...::::.: .. :...:. : .... ..:
NP_000 SLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTV
540 550 560 570 580 590
660 670 680 690 700 710
pF1KB0 SGIDT--QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLS
: . ...:..:::.:. : : .. . :. . .. .. . ..: .. : :.
NP_000 IKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLT
600 610 620 630 640 650
720 730 740 750 760 770
pF1KB0 DAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSA
:.. .::: . ..... ....:: : :: .. :. ... ... . ..
NP_000 TLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNED
660 670 680 690 700 710
780 790 800 810 820 830
pF1KB0 YNTAVNSARDAVRNLTEVVPQLLDQLRTVEQKR-PASNVSASIQRIRELIAQTRSVASKI
.. :...: ..: .::. .:.: ......:. : .:.: ...:::::: :.:..:::.
NP_000 FKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKV
720 730 740 750 760 770
840 850 860 870 880 890
pF1KB0 QVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKK
: : :.:.:.:::. ....:::..:::::... : .: : : ..:..:::.:.:..
NP_000 AVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSR-ENGGTENMFVMYLGNKDASR
780 790 800 810 820 830
900 910 920 930 940 950
pF1KB0 EYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWP--AYFSIVKIERVGKHGKVFLTVP
.:.:.:. . .:. ::::: ...:. .:. ..: : .. ::..:. . ... :
NP_000 DYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKG
840 850 860 870 880 890
960 970 980 990 1000 1010
pF1KB0 SLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELAT
. :: : . . ....::.::::..:::::: : .::::. :..: . ::.::
NP_000 ATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDD
900 910 920 930 940 950
1020 1030 1040 1050 1060 1070
pF1KB0 LNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFG
::..:.::::::. .:.. . :: : : .. . .:.:.::: : .
NP_000 LNENVLSLYNFKKTFNLNTTEVEPCRRRK-----EESDKNYFEGTGYARV----PTQPHA
960 970 980 990 1000
1080 1090 1100 1110 1120 1130
pF1KB0 QVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQ
. : ..: .: ::... ::. :. :....: : : : .. : : : . :
NP_000 PIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKLMVRYKLN-SELPK--ERGVGDA-
1010 1020 1030 1040 1050 1060
1140 1150 1160 1170 1180
pF1KB0 INDAKYHEISI-IYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALR
::... : :.: : . .:.: . :: ... .:.: . :. :.:: : : . .
NP_000 INNGRDHSIQIKIGKLQKRMWINVDVQNTI-IDGEVF--DFSTYYLGGIPIAIRER--FN
1070 1080 1090 1100 1110
1190 1200 1210 1220 1230 1240
pF1KB0 AHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFN-GQSFIASI
: ::::::.. :: .... ..:.:: : :: . : : :. : .. .
NP_000 ISTP---AFRGCMKNL---KKTSGVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTD
1120 1130 1140 1150 1160 1170
1250 1260 1270 1280 1290 1300
pF1KB0 QKISFFDGFEGGFNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVK--GIKVQSVDKQ
. : ....:.:.:.::.:.:. . . . ....:..: . .... : . . .
NP_000 LGLPPTDHLQASFGFQTFQPSGILLDHQTWTRNLQVTLEDGYIELSTSDSGGPIFKSPQT
1180 1190 1200 1210 1220 1230
1310 1320 1330 1340 1350 1360
pF1KB0 YNDGLSHFV--ISSVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQY
: ::: :.: ::. : : :: :. .:: .... ..:.... .:::
NP_000 YMDGLLHYVSVISDNSGLRL-LIDDQLLRNSK-----RLKHISSSRQSLRLGGS------
1240 1250 1260 1270 1280
1370 1380 1390 1400 1410 1420
pF1KB0 ANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKA
:: :::::.. :.. . :: :. . : .:: : ... :...: : . ..: :.
NP_000 -NFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLNKPPFLMLLKGSTRFNKTKT
1290 1300 1310 1320 1330 1340
1430 1440 1450 1460 1470 1480
pF1KB0 SQNKKGGKSKDAPSWDPVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEH
. .. .:.: .: ..:. . . : . .: . : :.: .:. :.
NP_000 FRINQ--LLQDTPVASPRSVKVWQ------DACSPLPKTQANHGALQFGDIPTSHLLFKL
1350 1360 1370 1380 1390
1490 1500 1510 1520 1530 1540
pF1KB0 LKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRS
. . .:::.. ..: ::.:..:... . :.::.:.:..::::. ... :::.:.:
NP_000 PQELLKPRSQFAVDMQTTSSRGLVFHTGTK--NSFMALYLSKGRLVFALGTDGKKLRIKS
1400 1410 1420 1430 1440 1450
1550 1560 1570 1580 1590 1600
pF1KB0 QEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVK
.:: ::: :: :.: .. .::::.::::. : ::: . .: .:..:.:::. :: :
NP_000 KEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGN-STISIRAPVYLGSPPSGKP-K
1460 1470 1480 1490 1500
1610 1620 1630 1640 1650 1660
pF1KB0 NVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESF
.. : :: :::.:.::.. . . :..:.:. :. ::.: : ::: :::.::: .:
NP_000 SLPTN---SFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSV
1510 1520 1530 1540 1550 1560
1670 1680 1690 1700 1710 1720
pF1KB0 NIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQ
.: .:...: .:::: .: :.: : :..: :... :.: .....: ::::::::
NP_000 LLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQ
1570 1580 1590 1600 1610 1620
1730 1740 1750 1760 1770 1780
pF1KB0 SLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLA
:::::.:: ..: .....:..:.. ....: . : . .::. .::.: .: : :.
NP_000 SLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAPANLTTLRIP
1630 1640 1650 1660 1670 1680
1790 1800 1810 1820
pF1KB0 PSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSINSCPAA
: : ::.:.. .. :: ..: :.: ::.:.::
NP_000 VWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ
1690 1700 1710 1720
>>XP_016881233 (OMIM: 226650,226700,245660,600805) PREDI (1856 aa)
initn: 2033 init1: 610 opt: 948 Z-score: 548.9 bits: 114.8 E(85289): 7.7e-24
Smith-Waterman score: 2993; 31.7% identity (64.1% similar) in 1826 aa overlap (40-1821:155-1854)
10 20 30 40 50 60
pF1KB0 VLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALG----RLPPA--
: :: .. .:. :.::. :::
XP_016 SREELMTVLSRLADVRIQGLYFTETQRLTLSEVGLEEASDTGSGRIALAVEICACPPAYA
130 140 150 160 170 180
70 80 90 100 110
pF1KB0 ---AEKCNAGFFHT----LSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDG
. :. :... .:.::::.:::.::.: :::: ::.::.::.:::::.: .:
XP_016 GDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEG
190 200 210 220 230 240
120 130 140 150 160 170
pF1KB0 YIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGN
: :....:. :. ::: :: .:: .: ..: ::: :. .:.: .::::::::.::
XP_016 YYGNAVHGS---CRACPC--PHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGN
250 260 270 280 290
180 190 200 210 220 230
pF1KB0 PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK
: .:..:. :.:..: ::
XP_016 PQKFGGSCQPCSCNSN--------------GQL---------------------------
300 310
240 250 260 270 280 290
pF1KB0 NCAVCNCGGGPCDSVTGECL-EEGFEPPTGMDCPTISCDKCVWDLTDDLRLAALSIEEGK
: : .::.:. .: . . .: .::.:: : .:: . ... :
XP_016 ---------GSCHPLTGDCINQEPKDSSPAEECD--DCDSCVMTLLNDLATMGEQLRLVK
320 330 340 350 360
300 310 320 330 340 350
pF1KB0 SGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEE
: . ..:..:. ... .... :...: . .. . . .:.. : . .: .. :
XP_016 SQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFET
370 380 390 400 410 420
360 370 380 390 400
pF1KB0 LVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEI--NNKMLYY------GE
: :: . :::.: .. ...:.:.: .:... ::... : ..: ::
XP_016 LQEKAQVNSRKAQTLN----NNVNRATQ---SAKELDVKIKNVIRNVHILLKQISGTDGE
430 440 450 460 470 480
410 420 430 440 450 460
pF1KB0 EHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEAD--EAYELLSQAESWQRLHN
... ..:.. . ::.:..:.:.:. : ..: . ::: :. ::.. ..::. :.
XP_016 GNNVPSGDFSREWAEAQRMMRELRNRN-F--GKHLREAEADKRESQLLLNRIRTWQKTHQ
490 500 510 520 530
470 480 490 500 510 520
pF1KB0 -ETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMN----RATAARQRDHEKQQ
:. : . ..:..:.::::::. :..: ...:. .: :: .: :: :
XP_016 GENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQR----QV
540 550 560 570 580 590
530 540 550 560 570 580
pF1KB0 ERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLS
... . . :.:. .:: ..:. .. :. . : .. :..::. :. .::
XP_016 KEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELS
600 610 620 630 640 650
590 600 610 620 630
pF1KB0 NLSH--DLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEAN
. .::.:: ::..::. :..: . .... . ::. :.::...::::.: .. :.
XP_016 RSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAE
660 670 680 690 700 710
640 650 660 670 680 690
pF1KB0 ETAEFALNTTDRIYDAVSGIDT--QIIYHKDESENLLNQARELQAKAESSSDEAVADTSR
..:. : .... ..: : . ...:..:::.:. : : .. . :. . ..
XP_016 DAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQ
720 730 740 750 760 770
700 710 720 730 740 750
pF1KB0 RVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMA
.. . ..: .. : :. :.. .::: . ..... ....:: : :: .. :.
XP_016 TLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQ
780 790 800 810 820 830
760 770 780 790 800 810
pF1KB0 NNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQKR-PASNVSASI
... ... . .. .. :...: ..: .::. .:.: ......:. : .:.: ..
XP_016 TDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNM
840 850 860 870 880 890
820 830 840 850 860 870
pF1KB0 QRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELT
.:::::: :.:..:::. : : :.:.:.:::. ....:::..:::::... : .: :
XP_016 DRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSR-ENG
900 910 920 930 940 950
880 890 900 910 920 930
pF1KB0 ETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWP--AYFSI
: ..:..:::.:.:...:.:.:. . .:. ::::: ...:. .:. ..: : ..
XP_016 GTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDR
960 970 980 990 1000 1010
940 950 960 970 980 990
pF1KB0 VKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKL
::..:. . ... : . :: : . . ....::.::::..:::::: : .:::
XP_016 VKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKL
1020 1030 1040 1050 1060 1070
1000 1010 1020 1030 1040 1050
pF1KB0 PTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFD
:. :..: . ::.:: ::..:.::::::. .:.. . :: : : .. . .:.
XP_016 PSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRK-----EESDKNYFE
1080 1090 1100 1110 1120
1060 1070 1080 1090 1100 1110
pF1KB0 GSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVFYDF
:.::: : . . . : ..: .: ::... ::. :. :....: : : : .
XP_016 GTGYARVPTQPH----APIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKLMVRYKL
1130 1140 1150 1160 1170 1180
1120 1130 1140 1150 1160 1170
pF1KB0 GFSGGPVHLEDTLKKAQINDAKYHEISI-IYHNDKKMILVVDRRHVKSMDNEKMKIPFTD
. . . : . : ::... : :.: : . .:.: . :: ... .:.: . :.
XP_016 N---SELPKERGVGDA-INNGRDHSIQIKIGKLQKRMWINVDVQNTI-IDGEVF--DFST
1190 1200 1210 1220 1230
1180 1190 1200 1210 1220 1230
pF1KB0 IYIGGAPPEILQSRALRAHLPLDI-NFRGCMKGFQFQKKDFNLLEQTETLGVGYGCPEDS
:.:: : :.: .. .. ::::::.. :: .... ..:.:: : ::
XP_016 YYLGGIPI------AIRERFNISTPAFRGCMKNL---KKTSGVVRLNDTVGVTKKCSEDW
1240 1250 1260 1270 1280
1240 1250 1260 1270 1280
pF1KB0 LISRRAYFN--GQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGSDVFSISLDNG
. : : :. :: .... . : ....:.:.:.::.:.:. . . . ....:..:
XP_016 KLVRSASFSRGGQLSFTDLG-LPPTDHLQASFGFQTFQPSGILLDHQTWTRNLQVTLEDG
1290 1300 1310 1320 1330 1340
1290 1300 1310 1320 1330 1340
pF1KB0 TVIMDVK--GIKVQSVDKQYNDGLSHFV--ISSVSPTRYELIVDKSRVGSKNPTKGKIEQ
. .... : . . . : ::: :.: ::. : : :: :. .:: ....
XP_016 YIELSTSDSGGPIFKSPQTYMDGLLHYVSVISDNSGLRL-LIDDQLLRNSK-----RLKH
1350 1360 1370 1380 1390 1400
1350 1360 1370 1380 1390 1400
pF1KB0 TQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIE
..:.... .::: :: :::::.. :.. . :: :. . : .:: : ..
XP_016 ISSSRQSLRLGGS-------NFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLN
1410 1420 1430 1440 1450
1410 1420 1430 1440 1450 1460
pF1KB0 SSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLPERNTPRNSHCHLSNSPRA
. :...: : . ..: :. . .. .:.: .: ..:. . . : . .:
XP_016 KPPFLMLLKGSTRFNKTKTFRINQ--LLQDTPVASPRSVKVWQ------DACSPLPKTQA
1460 1470 1480 1490 1500
1470 1480 1490 1500 1510 1520
pF1KB0 IEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLA
. : :.: .:. :. . . .:::.. ..: ::.:..:... . :.::.:.:.
XP_016 NHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTK--NSFMALYLS
1510 1520 1530 1540 1550 1560
1530 1540 1550 1560 1570 1580
pF1KB0 HGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEAT
.::::. ... :::.:.:.:: ::: :: :.: .. .::::.::::. : ::: . .:
XP_016 KGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGN-ST
1570 1580 1590 1600 1610 1620
1590 1600 1610 1620 1630 1640
pF1KB0 WKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPM
.:..:.:::. :: :.. :: : :::.:.::.. . . :..:.:. :. ::.
XP_016 ISIRAPVYLGSPPSGKP-KSLPTNS---FVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPL
1630 1640 1650 1660 1670
1650 1660 1670 1680 1690 1700
pF1KB0 ETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKNGQV
: : ::: :::.::: .: .: .:...: .:::: .: :.: : :..: :... :.:
XP_016 EKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKV
1680 1690 1700 1710 1720 1730
1710 1720 1730 1740 1750 1760
pF1KB0 IVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDH
.....: :::::::::::::.:: ..: .....:..:.. ....: . : .
XP_016 TASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPAST
1740 1750 1760 1770 1780 1790
1770 1780 1790 1800 1810 1820
pF1KB0 REPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSINSCPAA
.::. .::.: .: : :. : : ::.:.. .. :: ..: :.: ::.:.::
XP_016 QEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ
1800 1810 1820 1830 1840 1850
>>XP_016881232 (OMIM: 226650,226700,245660,600805) PREDI (2626 aa)
initn: 2033 init1: 610 opt: 948 Z-score: 547.2 bits: 115.0 E(85289): 9.6e-24
Smith-Waterman score: 2993; 31.7% identity (64.1% similar) in 1826 aa overlap (40-1821:925-2624)
10 20 30 40 50 60
pF1KB0 VLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALG----RLPPA--
: :: .. .:. :.::. :::
XP_016 SREELMTVLSRLADVRIQGLYFTETQRLTLSEVGLEEASDTGSGRIALAVEICACPPAYA
900 910 920 930 940 950
70 80 90 100 110
pF1KB0 ---AEKCNAGFFHT----LSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDG
. :. :... .:.::::.:::.::.: :::: ::.::.::.:::::.: .:
XP_016 GDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEG
960 970 980 990 1000 1010
120 130 140 150 160 170
pF1KB0 YIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGN
: :....:. :. ::: :: .:: .: ..: ::: :. .:.: .::::::::.::
XP_016 YYGNAVHGS---CRACPC--PHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGN
1020 1030 1040 1050 1060
180 190 200 210 220 230
pF1KB0 PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK
: .:..:. :.:..: ::
XP_016 PQKFGGSCQPCSCNSN--------------GQL---------------------------
1070 1080
240 250 260 270 280 290
pF1KB0 NCAVCNCGGGPCDSVTGECL-EEGFEPPTGMDCPTISCDKCVWDLTDDLRLAALSIEEGK
: : .::.:. .: . . .: .::.:: : .:: . ... :
XP_016 ---------GSCHPLTGDCINQEPKDSSPAEECD--DCDSCVMTLLNDLATMGEQLRLVK
1090 1100 1110 1120 1130
300 310 320 330 340 350
pF1KB0 SGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEE
: . ..:..:. ... .... :...: . .. . . .:.. : . .: .. :
XP_016 SQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFET
1140 1150 1160 1170 1180 1190
360 370 380 390 400
pF1KB0 LVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEI--NNKMLYY------GE
: :: . :::.: .. ...:.:.: .:... ::... : ..: ::
XP_016 LQEKAQVNSRKAQTLN----NNVNRATQ---SAKELDVKIKNVIRNVHILLKQISGTDGE
1200 1210 1220 1230 1240 1250
410 420 430 440 450 460
pF1KB0 EHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEAD--EAYELLSQAESWQRLHN
... ..:.. . ::.:..:.:.:. : ..: . ::: :. ::.. ..::. :.
XP_016 GNNVPSGDFSREWAEAQRMMRELRNRN-F--GKHLREAEADKRESQLLLNRIRTWQKTHQ
1260 1270 1280 1290 1300
470 480 490 500 510 520
pF1KB0 -ETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMN----RATAARQRDHEKQQ
:. : . ..:..:.::::::. :..: ...:. .: :: .: :: :
XP_016 GENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQR----QV
1310 1320 1330 1340 1350 1360
530 540 550 560 570 580
pF1KB0 ERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLS
... . . :.:. .:: ..:. .. :. . : .. :..::. :. .::
XP_016 KEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELS
1370 1380 1390 1400 1410 1420
590 600 610 620 630
pF1KB0 NLSH--DLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEAN
. .::.:: ::..::. :..: . .... . ::. :.::...::::.: .. :.
XP_016 RSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAE
1430 1440 1450 1460 1470 1480
640 650 660 670 680 690
pF1KB0 ETAEFALNTTDRIYDAVSGIDT--QIIYHKDESENLLNQARELQAKAESSSDEAVADTSR
..:. : .... ..: : . ...:..:::.:. : : .. . :. . ..
XP_016 DAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQ
1490 1500 1510 1520 1530 1540
700 710 720 730 740 750
pF1KB0 RVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMA
.. . ..: .. : :. :.. .::: . ..... ....:: : :: .. :.
XP_016 TLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQ
1550 1560 1570 1580 1590 1600
760 770 780 790 800 810
pF1KB0 NNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQKR-PASNVSASI
... ... . .. .. :...: ..: .::. .:.: ......:. : .:.: ..
XP_016 TDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNM
1610 1620 1630 1640 1650 1660
820 830 840 850 860 870
pF1KB0 QRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELT
.:::::: :.:..:::. : : :.:.:.:::. ....:::..:::::... : .: :
XP_016 DRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSR-ENG
1670 1680 1690 1700 1710 1720
880 890 900 910 920 930
pF1KB0 ETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWP--AYFSI
: ..:..:::.:.:...:.:.:. . .:. ::::: ...:. .:. ..: : ..
XP_016 GTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDR
1730 1740 1750 1760 1770 1780
940 950 960 970 980 990
pF1KB0 VKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKL
::..:. . ... : . :: : . . ....::.::::..:::::: : .:::
XP_016 VKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKL
1790 1800 1810 1820 1830 1840
1000 1010 1020 1030 1040 1050
pF1KB0 PTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFD
:. :..: . ::.:: ::..:.::::::. .:.. . :: : : .. . .:.
XP_016 PSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRK-----EESDKNYFE
1850 1860 1870 1880 1890
1060 1070 1080 1090 1100 1110
pF1KB0 GSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVFYDF
:.::: : . . . : ..: .: ::... ::. :. :....: : : : .
XP_016 GTGYARVPTQPH----APIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKLMVRYKL
1900 1910 1920 1930 1940 1950
1120 1130 1140 1150 1160 1170
pF1KB0 GFSGGPVHLEDTLKKAQINDAKYHEISI-IYHNDKKMILVVDRRHVKSMDNEKMKIPFTD
. . . : . : ::... : :.: : . .:.: . :: ... .:.: . :.
XP_016 N---SELPKERGVGDA-INNGRDHSIQIKIGKLQKRMWINVDVQNTI-IDGEVF--DFST
1960 1970 1980 1990 2000
1180 1190 1200 1210 1220 1230
pF1KB0 IYIGGAPPEILQSRALRAHLPLDI-NFRGCMKGFQFQKKDFNLLEQTETLGVGYGCPEDS
:.:: : :.: .. .. ::::::.. :: .... ..:.:: : ::
XP_016 YYLGGIPI------AIRERFNISTPAFRGCMKNL---KKTSGVVRLNDTVGVTKKCSEDW
2010 2020 2030 2040 2050
1240 1250 1260 1270 1280
pF1KB0 LISRRAYFN--GQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGSDVFSISLDNG
. : : :. :: .... . : ....:.:.:.::.:.:. . . . ....:..:
XP_016 KLVRSASFSRGGQLSFTDLG-LPPTDHLQASFGFQTFQPSGILLDHQTWTRNLQVTLEDG
2060 2070 2080 2090 2100 2110
1290 1300 1310 1320 1330 1340
pF1KB0 TVIMDVK--GIKVQSVDKQYNDGLSHFV--ISSVSPTRYELIVDKSRVGSKNPTKGKIEQ
. .... : . . . : ::: :.: ::. : : :: :. .:: ....
XP_016 YIELSTSDSGGPIFKSPQTYMDGLLHYVSVISDNSGLRL-LIDDQLLRNSK-----RLKH
2120 2130 2140 2150 2160 2170
1350 1360 1370 1380 1390 1400
pF1KB0 TQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIE
..:.... .::: :: :::::.. :.. . :: :. . : .:: : ..
XP_016 ISSSRQSLRLGGS-------NFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLN
2180 2190 2200 2210 2220
1410 1420 1430 1440 1450 1460
pF1KB0 SSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLPERNTPRNSHCHLSNSPRA
. :...: : . ..: :. . .. .:.: .: ..:. . . : . .:
XP_016 KPPFLMLLKGSTRFNKTKTFRINQ--LLQDTPVASPRSVKVWQ------DACSPLPKTQA
2230 2240 2250 2260 2270
1470 1480 1490 1500 1510 1520
pF1KB0 IEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLA
. : :.: .:. :. . . .:::.. ..: ::.:..:... . :.::.:.:.
XP_016 NHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTK--NSFMALYLS
2280 2290 2300 2310 2320 2330
1530 1540 1550 1560 1570 1580
pF1KB0 HGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEAT
.::::. ... :::.:.:.:: ::: :: :.: .. .::::.::::. : ::: . .:
XP_016 KGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGN-ST
2340 2350 2360 2370 2380 2390
1590 1600 1610 1620 1630 1640
pF1KB0 WKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPM
.:..:.:::. :: :.. :: : :::.:.::.. . . :..:.:. :. ::.
XP_016 ISIRAPVYLGSPPSGKP-KSLPTNS---FVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPL
2400 2410 2420 2430 2440
1650 1660 1670 1680 1690 1700
pF1KB0 ETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKNGQV
: : ::: :::.::: .: .: .:...: .:::: .: :.: : :..: :... :.:
XP_016 EKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKV
2450 2460 2470 2480 2490 2500
1710 1720 1730 1740 1750 1760
pF1KB0 IVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDH
.....: :::::::::::::.:: ..: .....:..:.. ....: . : .
XP_016 TASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPAST
2510 2520 2530 2540 2550 2560
1770 1780 1790 1800 1810 1820
pF1KB0 REPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSINSCPAA
.::. .::.: .: : :. : : ::.:.. .. :: ..: :.: ::.:.::
XP_016 QEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ
2570 2580 2590 2600 2610 2620
1823 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 11:34:07 2016 done: Thu Nov 3 11:34:10 2016
Total Scan time: 19.080 Total Display time: 1.210
Function used was FASTA [36.3.4 Apr, 2011]