FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0054, 1036 aa 1>>>pF1KB0054 1036 - 1036 aa - 1036 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9419+/-0.000647; mu= 12.8869+/- 0.039 mean_var=122.7975+/-25.825, 0's: 0 Z-trim(108.4): 206 B-trim: 624 in 2/50 Lambda= 0.115739 statistics sampled from 16147 (16472) to 16147 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.523), E-opt: 0.2 (0.193), width: 16 Scan time: 9.780 The best scores are: opt bits E(85289) NP_858059 (OMIM: 300255) UDP-N-acetylglucosamine-- (1036) 6953 1174.0 0 NP_858058 (OMIM: 300255) UDP-N-acetylglucosamine-- (1046) 6883 1162.3 0 XP_016885396 (OMIM: 300255) PREDICTED: UDP-N-acety ( 665) 4511 766.1 0 XP_016885397 (OMIM: 300255) PREDICTED: UDP-N-acety ( 665) 4511 766.1 0 XP_016875496 (OMIM: 615855) PREDICTED: transmembra ( 618) 345 70.5 3.3e-11 NP_787057 (OMIM: 615855) transmembrane and TPR rep ( 774) 345 70.6 3.9e-11 XP_016875494 (OMIM: 615855) PREDICTED: transmembra ( 813) 345 70.6 4.1e-11 XP_016875493 (OMIM: 615855) PREDICTED: transmembra ( 875) 345 70.6 4.3e-11 NP_001180380 (OMIM: 615855) transmembrane and TPR ( 882) 345 70.6 4.4e-11 XP_016875492 (OMIM: 615855) PREDICTED: transmembra ( 888) 345 70.6 4.4e-11 XP_005253556 (OMIM: 615855) PREDICTED: transmembra ( 944) 345 70.6 4.6e-11 XP_016880977 (OMIM: 116946) PREDICTED: cell divisi ( 427) 252 54.9 1.1e-06 NP_001307250 (OMIM: 615856) transmembrane and TPR ( 591) 251 54.8 1.7e-06 XP_016880975 (OMIM: 116946) PREDICTED: cell divisi ( 720) 252 55.0 1.7e-06 XP_016880974 (OMIM: 116946) PREDICTED: cell divisi ( 721) 252 55.0 1.8e-06 XP_011523852 (OMIM: 116946) PREDICTED: cell divisi ( 727) 252 55.0 1.8e-06 XP_016880973 (OMIM: 116946) PREDICTED: cell divisi ( 762) 252 55.0 1.8e-06 NP_001280020 (OMIM: 116946) cell division cycle pr ( 763) 252 55.0 1.8e-06 XP_011523851 (OMIM: 116946) PREDICTED: cell divisi ( 769) 252 55.0 1.8e-06 XP_011523850 (OMIM: 116946) PREDICTED: cell divisi ( 769) 252 55.0 1.8e-06 NP_001280018 (OMIM: 116946) cell division cycle pr ( 823) 252 55.1 1.9e-06 NP_001247 (OMIM: 116946) cell division cycle prote ( 824) 252 55.1 1.9e-06 XP_011523848 (OMIM: 116946) PREDICTED: cell divisi ( 829) 252 55.1 2e-06 NP_001107563 (OMIM: 116946) cell division cycle pr ( 830) 252 55.1 2e-06 XP_016874373 (OMIM: 615856) PREDICTED: transmembra ( 719) 251 54.8 2e-06 NP_689801 (OMIM: 615856) transmembrane and TPR rep ( 836) 251 54.9 2.2e-06 XP_016875495 (OMIM: 615855) PREDICTED: transmembra ( 668) 241 53.2 5.9e-06 XP_011528323 (OMIM: 615098) PREDICTED: tetratricop (1390) 240 53.2 1.2e-05 XP_011528324 (OMIM: 615098) PREDICTED: tetratricop (1390) 240 53.2 1.2e-05 XP_011528322 (OMIM: 615098) PREDICTED: tetratricop (1400) 240 53.2 1.2e-05 XP_011528321 (OMIM: 615098) PREDICTED: tetratricop (1412) 240 53.2 1.2e-05 XP_006724234 (OMIM: 615098) PREDICTED: tetratricop (2363) 240 53.3 1.8e-05 XP_016884162 (OMIM: 615098) PREDICTED: tetratricop (2451) 240 53.4 1.9e-05 XP_011528320 (OMIM: 615098) PREDICTED: tetratricop (2455) 240 53.4 1.9e-05 XP_005261462 (OMIM: 615098) PREDICTED: tetratricop (2473) 240 53.4 1.9e-05 NP_001138890 (OMIM: 615098) tetratricopeptide repe (2481) 240 53.4 1.9e-05 XP_016874916 (OMIM: 606949) PREDICTED: anaphase-pr ( 498) 212 48.2 0.00013 XP_016874915 (OMIM: 606949) PREDICTED: anaphase-pr ( 498) 212 48.2 0.00013 XP_011534737 (OMIM: 608132,613464,615985) PREDICTE ( 276) 207 47.2 0.00015 NP_001275712 (OMIM: 608132,613464,615985) tetratri ( 276) 207 47.2 0.00015 XP_011536756 (OMIM: 606949) PREDICTED: anaphase-pr ( 579) 212 48.3 0.00015 NP_057322 (OMIM: 606949) anaphase-promoting comple ( 599) 212 48.3 0.00015 XP_016877941 (OMIM: 209900,600374,615982) PREDICTE ( 347) 208 47.5 0.00016 NP_001239607 (OMIM: 209900,600374,615982) Bardet-B ( 347) 208 47.5 0.00016 XP_011520151 (OMIM: 209900,600374,615982) PREDICTE ( 347) 208 47.5 0.00016 XP_016877940 (OMIM: 209900,600374,615982) PREDICTE ( 347) 208 47.5 0.00016 XP_011520150 (OMIM: 209900,600374,615982) PREDICTE ( 347) 208 47.5 0.00016 XP_016877942 (OMIM: 209900,600374,615982) PREDICTE ( 347) 208 47.5 0.00016 XP_016877943 (OMIM: 209900,600374,615982) PREDICTE ( 347) 208 47.5 0.00016 NP_001275711 (OMIM: 608132,613464,615985) tetratri ( 317) 207 47.3 0.00017 >>NP_858059 (OMIM: 300255) UDP-N-acetylglucosamine--pept (1036 aa) initn: 6953 init1: 6953 opt: 6953 Z-score: 6282.2 bits: 1174.0 E(85289): 0 Smith-Waterman score: 6953; 100.0% identity (100.0% similar) in 1036 aa overlap (1-1036:1-1036) 10 20 30 40 50 60 pF1KB0 MASSVGNVADSTGLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 MASSVGNVADSTGLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 LDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 LDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 AALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 AALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 AVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 AVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 ALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 ALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 EAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 EAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 LQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 LQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFAD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 AHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 AHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 SIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 SIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 LSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 LSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEAN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 HFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 HFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 ALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAVIDFKSNGHIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 ALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAVIDFKSNGHIY 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 DNRIVLNGIDLKAFLDSLPDVKIVKMKCPDGGDNADSSNTALNMPVIPMNTIAEAVIEMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 DNRIVLNGIDLKAFLDSLPDVKIVKMKCPDGGDNADSSNTALNMPVIPMNTIAEAVIEMI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 NRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 NRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 YKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 YKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 HVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 HVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 KNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 KNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAG 970 980 990 1000 1010 1020 1030 pF1KB0 NKPDHMIKPVEVTESA :::::::::::::::: NP_858 NKPDHMIKPVEVTESA 1030 >>NP_858058 (OMIM: 300255) UDP-N-acetylglucosamine--pept (1046 aa) initn: 6883 init1: 6883 opt: 6883 Z-score: 6218.9 bits: 1162.3 E(85289): 0 Smith-Waterman score: 6923; 99.0% identity (99.0% similar) in 1046 aa overlap (1-1036:1-1046) 10 20 30 40 50 pF1KB0 MASSVGNVADST----------GLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLL :::::::::::: :::::::::::::::::::::::::::::::::::::: NP_858 MASSVGNVADSTEPTKRMLSFQGLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB0 LSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 LSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKP 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 DFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 DFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACY 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB0 LKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 LKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARI 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB0 FDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 FDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLA 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB0 NALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 NALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEF 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB0 AAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 AAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTR 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB0 AIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 AIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWT 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB0 DYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 DYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHK 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB0 PPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 PPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTN 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB0 FRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 FRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQA 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB0 MWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 MWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAV 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB0 IDFKSNGHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPDGGDNADSSNTALNMPVIPMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 IDFKSNGHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPDGGDNADSSNTALNMPVIPMN 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB0 TIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 TIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPED 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB0 AIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 AIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRI 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB0 IFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 IFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQL 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KB0 TCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_858 TCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLY 970 980 990 1000 1010 1020 1020 1030 pF1KB0 LQMWEHYAAGNKPDHMIKPVEVTESA :::::::::::::::::::::::::: NP_858 LQMWEHYAAGNKPDHMIKPVEVTESA 1030 1040 >>XP_016885396 (OMIM: 300255) PREDICTED: UDP-N-acetylglu (665 aa) initn: 4511 init1: 4511 opt: 4511 Z-score: 4081.3 bits: 766.1 E(85289): 0 Smith-Waterman score: 4511; 100.0% identity (100.0% similar) in 665 aa overlap (372-1036:1-665) 350 360 370 380 390 400 pF1KB0 KALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDV :::::::::::::::::::::::::::::: XP_016 MHYKEAIRISPTFADAYSNMGNTLKEMQDV 10 20 30 410 420 430 440 450 460 pF1KB0 QGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAH 40 50 60 70 80 90 470 480 490 500 510 520 pF1KB0 CLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLC 100 110 120 130 140 150 530 540 550 560 570 580 pF1KB0 LDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCY 160 170 180 190 200 210 590 600 610 620 630 640 pF1KB0 ALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELF 220 230 240 250 260 270 650 660 670 680 690 700 pF1KB0 ALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANM 280 290 300 310 320 330 710 720 730 740 750 760 pF1KB0 FPHLKKKAVIDFKSNGHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPDGGDNADSSNTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FPHLKKKAVIDFKSNGHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPDGGDNADSSNTA 340 350 360 370 380 390 770 780 790 800 810 820 pF1KB0 LNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTT 400 410 420 430 440 450 830 840 850 860 870 880 pF1KB0 RSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQ 460 470 480 490 500 510 890 900 910 920 930 940 pF1KB0 NMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETL 520 530 540 550 560 570 950 960 970 980 990 1000 pF1KB0 ASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQ 580 590 600 610 620 630 1010 1020 1030 pF1KB0 YTMELERLYLQMWEHYAAGNKPDHMIKPVEVTESA ::::::::::::::::::::::::::::::::::: XP_016 YTMELERLYLQMWEHYAAGNKPDHMIKPVEVTESA 640 650 660 >>XP_016885397 (OMIM: 300255) PREDICTED: UDP-N-acetylglu (665 aa) initn: 4511 init1: 4511 opt: 4511 Z-score: 4081.3 bits: 766.1 E(85289): 0 Smith-Waterman score: 4511; 100.0% identity (100.0% similar) in 665 aa overlap (372-1036:1-665) 350 360 370 380 390 400 pF1KB0 KALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDV :::::::::::::::::::::::::::::: XP_016 MHYKEAIRISPTFADAYSNMGNTLKEMQDV 10 20 30 410 420 430 440 450 460 pF1KB0 QGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAH 40 50 60 70 80 90 470 480 490 500 510 520 pF1KB0 CLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLC 100 110 120 130 140 150 530 540 550 560 570 580 pF1KB0 LDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCY 160 170 180 190 200 210 590 600 610 620 630 640 pF1KB0 ALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELF 220 230 240 250 260 270 650 660 670 680 690 700 pF1KB0 ALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANM 280 290 300 310 320 330 710 720 730 740 750 760 pF1KB0 FPHLKKKAVIDFKSNGHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPDGGDNADSSNTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FPHLKKKAVIDFKSNGHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPDGGDNADSSNTA 340 350 360 370 380 390 770 780 790 800 810 820 pF1KB0 LNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTT 400 410 420 430 440 450 830 840 850 860 870 880 pF1KB0 RSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQ 460 470 480 490 500 510 890 900 910 920 930 940 pF1KB0 NMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETL 520 530 540 550 560 570 950 960 970 980 990 1000 pF1KB0 ASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQ 580 590 600 610 620 630 1010 1020 1030 pF1KB0 YTMELERLYLQMWEHYAAGNKPDHMIKPVEVTESA ::::::::::::::::::::::::::::::::::: XP_016 YTMELERLYLQMWEHYAAGNKPDHMIKPVEVTESA 640 650 660 >>XP_016875496 (OMIM: 615855) PREDICTED: transmembrane a (618 aa) initn: 623 init1: 268 opt: 345 Z-score: 322.3 bits: 70.5 E(85289): 3.3e-11 Smith-Waterman score: 472; 28.5% identity (58.2% similar) in 404 aa overlap (61-460:202-600) 40 50 60 70 80 90 pF1KB0 ERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYK :.: . : . ... : :... : .: : XP_016 NRCGATTLIVSTVLLLLLFSWKTVKQNEIWLSRESLFRS-GVQTLPHNAKVHYNYANFLK 180 190 200 210 220 230 100 110 120 130 140 150 pF1KB0 ERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVR ..:. .::: ::: ::.: : .. ::.. . : : . : ::: .:. . XP_016 DQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TRDTAEAKMYYQRALQLHPQHNRAL 240 250 260 270 280 160 170 180 190 200 210 pF1KB0 SDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTL .::::::. . ::: . .:. :.:: :.:.:. .. : .. : . .. .. XP_016 FNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKN 290 300 310 320 330 340 220 230 240 250 260 270 pF1KB0 DPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAID :. : . : : : .. . ..::: : .:..:::.: :. ::. .: : ..: . XP_016 CPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEE 350 360 370 380 390 400 280 290 300 310 320 330 pF1KB0 TYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQ :.::... : . :. . : :: . :. : : :.. . ::.. . XP_016 WYKRALQVA-HKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVM 410 420 430 440 450 460 340 350 360 370 380 pF1KB0 GNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISP----TFAD :. .:: .. . . . :... ..: . ..:: .:....: .... XP_016 GQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVISE 470 480 490 500 510 520 390 400 410 420 430 440 pF1KB0 AYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTAL . . :: :.:.. .. :.. : :.:.:: :.: :...:.. .:. : : :. :: XP_016 LFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERAL 530 540 550 560 570 580 450 460 470 480 490 500 pF1KB0 KLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLS .: :: ::: XP_016 QLVPDSKLLKENLAKLDRLEKRLQEVREKDQT 590 600 610 >>NP_787057 (OMIM: 615855) transmembrane and TPR repeat- (774 aa) initn: 877 init1: 268 opt: 345 Z-score: 320.9 bits: 70.6 E(85289): 3.9e-11 Smith-Waterman score: 472; 28.5% identity (58.2% similar) in 404 aa overlap (61-460:358-756) 40 50 60 70 80 90 pF1KB0 ERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYK :.: . : . ... : :... : .: : NP_787 NRCGATTLIVSTVLLLLLFSWKTVKQNEIWLSRESLFRS-GVQTLPHNAKVHYNYANFLK 330 340 350 360 370 380 100 110 120 130 140 150 pF1KB0 ERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVR ..:. .::: ::: ::.: : .. ::.. . : : . : ::: .:. . NP_787 DQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TRDTAEAKMYYQRALQLHPQHNRAL 390 400 410 420 430 440 160 170 180 190 200 210 pF1KB0 SDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTL .::::::. . ::: . .:. :.:: :.:.:. .. : .. : . .. .. NP_787 FNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKN 450 460 470 480 490 500 220 230 240 250 260 270 pF1KB0 DPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAID :. : . : : : .. . ..::: : .:..:::.: :. ::. .: : ..: . NP_787 CPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEE 510 520 530 540 550 560 280 290 300 310 320 330 pF1KB0 TYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQ :.::... : . :. . : :: . :. : : :.. . ::.. . NP_787 WYKRALQVA-HKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVM 570 580 590 600 610 620 340 350 360 370 380 pF1KB0 GNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISP----TFAD :. .:: .. . . . :... ..: . ..:: .:....: .... NP_787 GQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVISE 630 640 650 660 670 680 390 400 410 420 430 440 pF1KB0 AYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTAL . . :: :.:.. .. :.. : :.:.:: :.: :...:.. .:. : : :. :: NP_787 LFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERAL 690 700 710 720 730 740 450 460 470 480 490 500 pF1KB0 KLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLS .: :: ::: NP_787 QLVPDSKLLKENLAKLDRLEKRLQEVREKDQT 750 760 770 >>XP_016875494 (OMIM: 615855) PREDICTED: transmembrane a (813 aa) initn: 823 init1: 268 opt: 345 Z-score: 320.5 bits: 70.6 E(85289): 4.1e-11 Smith-Waterman score: 472; 28.5% identity (58.2% similar) in 404 aa overlap (61-460:397-795) 40 50 60 70 80 90 pF1KB0 ERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYK :.: . : . ... : :... : .: : XP_016 NRCGATTLIVSTVLLLLLFSWKTVKQNEIWLSRESLFRS-GVQTLPHNAKVHYNYANFLK 370 380 390 400 410 420 100 110 120 130 140 150 pF1KB0 ERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVR ..:. .::: ::: ::.: : .. ::.. . : : . : ::: .:. . XP_016 DQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TRDTAEAKMYYQRALQLHPQHNRAL 430 440 450 460 470 480 160 170 180 190 200 210 pF1KB0 SDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTL .::::::. . ::: . .:. :.:: :.:.:. .. : .. : . .. .. XP_016 FNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKN 490 500 510 520 530 540 220 230 240 250 260 270 pF1KB0 DPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAID :. : . : : : .. . ..::: : .:..:::.: :. ::. .: : ..: . XP_016 CPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEE 550 560 570 580 590 600 280 290 300 310 320 330 pF1KB0 TYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQ :.::... : . :. . : :: . :. : : :.. . ::.. . XP_016 WYKRALQVA-HKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVM 610 620 630 640 650 660 340 350 360 370 380 pF1KB0 GNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISP----TFAD :. .:: .. . . . :... ..: . ..:: .:....: .... XP_016 GQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVISE 670 680 690 700 710 720 390 400 410 420 430 440 pF1KB0 AYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTAL . . :: :.:.. .. :.. : :.:.:: :.: :...:.. .:. : : :. :: XP_016 LFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERAL 730 740 750 760 770 780 450 460 470 480 490 500 pF1KB0 KLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLS .: :: ::: XP_016 QLVPDSKLLKENLAKLDRLEKRLQEVREKDQT 790 800 810 >>XP_016875493 (OMIM: 615855) PREDICTED: transmembrane a (875 aa) initn: 823 init1: 268 opt: 345 Z-score: 320.1 bits: 70.6 E(85289): 4.3e-11 Smith-Waterman score: 472; 28.5% identity (58.2% similar) in 404 aa overlap (61-460:459-857) 40 50 60 70 80 90 pF1KB0 ERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYK :.: . : . ... : :... : .: : XP_016 NRCGATTLIVSTVLLLLLFSWKTVKQNEIWLSRESLFRS-GVQTLPHNAKVHYNYANFLK 430 440 450 460 470 480 100 110 120 130 140 150 pF1KB0 ERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVR ..:. .::: ::: ::.: : .. ::.. . : : . : ::: .:. . XP_016 DQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TRDTAEAKMYYQRALQLHPQHNRAL 490 500 510 520 530 540 160 170 180 190 200 210 pF1KB0 SDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTL .::::::. . ::: . .:. :.:: :.:.:. .. : .. : . .. .. XP_016 FNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKN 550 560 570 580 590 600 220 230 240 250 260 270 pF1KB0 DPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAID :. : . : : : .. . ..::: : .:..:::.: :. ::. .: : ..: . XP_016 CPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEE 610 620 630 640 650 660 280 290 300 310 320 330 pF1KB0 TYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQ :.::... : . :. . : :: . :. : : :.. . ::.. . XP_016 WYKRALQVA-HKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVM 670 680 690 700 710 720 340 350 360 370 380 pF1KB0 GNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISP----TFAD :. .:: .. . . . :... ..: . ..:: .:....: .... XP_016 GQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVISE 730 740 750 760 770 780 390 400 410 420 430 440 pF1KB0 AYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTAL . . :: :.:.. .. :.. : :.:.:: :.: :...:.. .:. : : :. :: XP_016 LFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERAL 790 800 810 820 830 840 450 460 470 480 490 500 pF1KB0 KLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLS .: :: ::: XP_016 QLVPDSKLLKENLAKLDRLEKRLQEVREKDQT 850 860 870 >>NP_001180380 (OMIM: 615855) transmembrane and TPR repe (882 aa) initn: 819 init1: 268 opt: 345 Z-score: 320.0 bits: 70.6 E(85289): 4.4e-11 Smith-Waterman score: 472; 28.5% identity (58.2% similar) in 404 aa overlap (61-460:466-864) 40 50 60 70 80 90 pF1KB0 ERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYK :.: . : . ... : :... : .: : NP_001 NRCGATTLIVSTVLLLLLFSWKTVKQNEIWLSRESLFRS-GVQTLPHNAKVHYNYANFLK 440 450 460 470 480 490 100 110 120 130 140 150 pF1KB0 ERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVR ..:. .::: ::: ::.: : .. ::.. . : : . : ::: .:. . NP_001 DQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TRDTAEAKMYYQRALQLHPQHNRAL 500 510 520 530 540 550 160 170 180 190 200 210 pF1KB0 SDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTL .::::::. . ::: . .:. :.:: :.:.:. .. : .. : . .. .. NP_001 FNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKN 560 570 580 590 600 610 220 230 240 250 260 270 pF1KB0 DPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAID :. : . : : : .. . ..::: : .:..:::.: :. ::. .: : ..: . NP_001 CPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEE 620 630 640 650 660 670 280 290 300 310 320 330 pF1KB0 TYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQ :.::... : . :. . : :: . :. : : :.. . ::.. . NP_001 WYKRALQVA-HKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVM 680 690 700 710 720 730 340 350 360 370 380 pF1KB0 GNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISP----TFAD :. .:: .. . . . :... ..: . ..:: .:....: .... NP_001 GQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVISE 740 750 760 770 780 790 390 400 410 420 430 440 pF1KB0 AYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTAL . . :: :.:.. .. :.. : :.:.:: :.: :...:.. .:. : : :. :: NP_001 LFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERAL 800 810 820 830 840 850 450 460 470 480 490 500 pF1KB0 KLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLS .: :: ::: NP_001 QLVPDSKLLKENLAKLDRLEKRLQEVREKDQT 860 870 880 >>XP_016875492 (OMIM: 615855) PREDICTED: transmembrane a (888 aa) initn: 877 init1: 268 opt: 345 Z-score: 320.0 bits: 70.6 E(85289): 4.4e-11 Smith-Waterman score: 470; 27.1% identity (57.1% similar) in 443 aa overlap (33-460:432-870) 10 20 30 40 50 pF1KB0 SSVGNVADSTGLAELAHREYQAGDFEAAERHCMQLWRQEPDN---TGVLLLL------SS ::. ... . .:.:.:. :. XP_016 VGSIPLVETIWDMRNLATIFLAVVMALLSLHCLAAFKRLEHKEVLVGLLFLVFPFIPASN 410 420 430 440 450 460 60 70 80 90 100 110 pF1KB0 IHFQCRRL--DRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPD . :. . .: .. ... : :... : .: :..:. .::: ::: ::.: : XP_016 LFFRVGFVVAERVLYMPRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPR 470 480 490 500 510 520 120 130 140 150 160 170 pF1KB0 FIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYL .. ::.. . : : . : ::: .:. . .::::::. . ::: . XP_016 HASALNNLGTL---TRDTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLK 530 540 550 560 570 180 190 200 210 220 230 pF1KB0 KAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIF .:. :.:: :.:.:. .. : .. : . .. .. :. : . : : : .. . XP_016 DSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLP 580 590 600 610 620 630 240 250 260 270 280 290 pF1KB0 DRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLAN ..::: : .:..:::.: :. ::. .: : ..: . :.::... : . :. XP_016 EKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVA-HKAEILSPLGA 640 650 660 670 680 690 300 310 320 330 340 350 pF1KB0 ALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFA . : :: . :. : : :.. . ::.. .:. .:: .. . . XP_016 LYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCL 700 710 720 730 740 750 360 370 380 390 400 pF1KB0 AAHSNLASVLQQQGKLQEALMHYKEAIRISP----TFADAYSNMGNTLKEMQDVQGALQC . :... ..: . ..:: .:....: .... . . :: :.:.. .. :.. XP_016 ECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVISELFFTKGNQLREQNLLDKAFES 760 770 780 790 800 810 410 420 430 440 450 460 pF1KB0 YTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVC : :.:.:: :.: :...:.. .:. : : :. ::.: :: ::: XP_016 YRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDSKLLKENLAKLDRLEK 820 830 840 850 860 870 470 480 490 500 510 520 pF1KB0 DWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINV XP_016 RLQEVREKDQT 880 1036 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 02:24:35 2016 done: Sat Nov 5 02:24:37 2016 Total Scan time: 9.780 Total Display time: 0.210 Function used was FASTA [36.3.4 Apr, 2011]