FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0065, 2041 aa 1>>>pF1KB0065 2041 - 2041 aa - 2041 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.0218+/-0.000577; mu= 12.6256+/- 0.036 mean_var=215.8247+/-47.105, 0's: 0 Z-trim(113.8): 379 B-trim: 1031 in 2/49 Lambda= 0.087302 statistics sampled from 22858 (23338) to 22858 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.598), E-opt: 0.2 (0.274), width: 16 Scan time: 21.150 The best scores are: opt bits E(85289) XP_006716951 (OMIM: 603785,615219) PREDICTED: mult (2041) 13162 1673.2 0 NP_003820 (OMIM: 603785,615219) multiple PDZ domai (2041) 13162 1673.2 0 XP_016870741 (OMIM: 603785,615219) PREDICTED: mult (2042) 12155 1546.3 0 XP_006716950 (OMIM: 603785,615219) PREDICTED: mult (2070) 11606 1477.2 0 XP_006716948 (OMIM: 603785,615219) PREDICTED: mult (2070) 11606 1477.2 0 XP_006716949 (OMIM: 603785,615219) PREDICTED: mult (2070) 11606 1477.2 0 NP_001317566 (OMIM: 603785,615219) multiple PDZ do (2070) 11606 1477.2 0 XP_016870747 (OMIM: 603785,615219) PREDICTED: mult (1461) 9478 1209.0 0 NP_001248335 (OMIM: 603785,615219) multiple PDZ do (2037) 9434 1203.6 0 XP_006716952 (OMIM: 603785,615219) PREDICTED: mult (2037) 9434 1203.6 0 XP_016870742 (OMIM: 603785,615219) PREDICTED: mult (2008) 8061 1030.7 0 XP_006716954 (OMIM: 603785,615219) PREDICTED: mult (2008) 8061 1030.7 0 NP_001248336 (OMIM: 603785,615219) multiple PDZ do (2008) 8061 1030.7 0 XP_016870745 (OMIM: 603785,615219) PREDICTED: mult (1971) 7812 999.3 0 XP_016870746 (OMIM: 603785,615219) PREDICTED: mult (1971) 7812 999.3 0 XP_016870744 (OMIM: 603785,615219) PREDICTED: mult (2000) 7812 999.3 0 XP_005251680 (OMIM: 603785,615219) PREDICTED: mult (2000) 7812 999.3 0 XP_016870743 (OMIM: 603785,615219) PREDICTED: mult (2000) 7812 999.3 0 XP_016870748 (OMIM: 603785,615219) PREDICTED: mult (1167) 7205 922.6 0 XP_011538772 (OMIM: 603199) PREDICTED: inaD-like p ( 954) 1538 208.8 2.3e-52 XP_011538768 (OMIM: 603199) PREDICTED: inaD-like p (1907) 937 133.4 2.3e-29 NP_795352 (OMIM: 603199) inaD-like protein [Homo s (1801) 926 132.0 5.8e-29 XP_005270398 (OMIM: 603199) PREDICTED: inaD-like p (1882) 926 132.0 6e-29 XP_016855490 (OMIM: 603199) PREDICTED: inaD-like p ( 992) 746 109.0 2.6e-22 XP_016855489 (OMIM: 603199) PREDICTED: inaD-like p (1634) 746 109.3 3.6e-22 XP_011538769 (OMIM: 603199) PREDICTED: inaD-like p (1856) 746 109.3 4e-22 XP_011538764 (OMIM: 603199) PREDICTED: inaD-like p (1937) 746 109.3 4.1e-22 XP_011538765 (OMIM: 603199) PREDICTED: inaD-like p (1937) 746 109.3 4.1e-22 XP_011538766 (OMIM: 603199) PREDICTED: inaD-like p (1921) 726 106.8 2.3e-21 XP_011538767 (OMIM: 603199) PREDICTED: inaD-like p (1912) 721 106.2 3.6e-21 XP_011538770 (OMIM: 603199) PREDICTED: inaD-like p (1515) 606 91.6 7e-17 XP_016855488 (OMIM: 603199) PREDICTED: inaD-like p (1854) 606 91.7 8.1e-17 XP_016855487 (OMIM: 603199) PREDICTED: inaD-like p (1879) 606 91.7 8.2e-17 XP_006710341 (OMIM: 603199) PREDICTED: inaD-like p (1296) 551 84.6 7.7e-15 XP_005270404 (OMIM: 603199) PREDICTED: inaD-like p (1300) 551 84.6 7.7e-15 XP_011538771 (OMIM: 603199) PREDICTED: inaD-like p (1344) 551 84.6 7.9e-15 XP_011533297 (OMIM: 609733) PREDICTED: ligand of N ( 567) 421 67.9 3.7e-10 NP_699202 (OMIM: 609733) ligand of Numb protein X ( 690) 421 68.0 4.2e-10 XP_016875923 (OMIM: 609733) PREDICTED: ligand of N ( 690) 421 68.0 4.2e-10 XP_016872774 (OMIM: 603583) PREDICTED: disks large ( 796) 364 60.8 6.7e-08 XP_016872770 (OMIM: 603583) PREDICTED: disks large ( 820) 364 60.9 6.9e-08 XP_016872769 (OMIM: 603583) PREDICTED: disks large ( 820) 364 60.9 6.9e-08 XP_016872768 (OMIM: 603583) PREDICTED: disks large ( 821) 364 60.9 6.9e-08 XP_016872765 (OMIM: 603583) PREDICTED: disks large ( 848) 364 60.9 7e-08 NP_001287912 (OMIM: 603583) disks large homolog 2 ( 852) 364 60.9 7e-08 XP_016872763 (OMIM: 603583) PREDICTED: disks large ( 866) 364 60.9 7.1e-08 NP_001355 (OMIM: 603583) disks large homolog 2 iso ( 870) 364 60.9 7.1e-08 XP_016872761 (OMIM: 603583) PREDICTED: disks large ( 871) 364 60.9 7.1e-08 XP_016872760 (OMIM: 603583) PREDICTED: disks large ( 872) 364 60.9 7.2e-08 XP_016872759 (OMIM: 603583) PREDICTED: disks large ( 873) 364 60.9 7.2e-08 >>XP_006716951 (OMIM: 603785,615219) PREDICTED: multiple (2041 aa) initn: 13162 init1: 13162 opt: 13162 Z-score: 8969.1 bits: 1673.2 E(85289): 0 Smith-Waterman score: 13162; 100.0% identity (100.0% similar) in 2041 aa overlap (1-2041:1-2041) 10 20 30 40 50 60 pF1KB0 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB0 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB0 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB0 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB0 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKVSEGSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKVSEGSLS 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB0 SFTFPLSGSSTSESLESSSKKNALASEIQGLRTVEMKKGPTDSLGISIAGGVGSPLGDVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SFTFPLSGSSTSESLESSSKKNALASEIQGLRTVEMKKGPTDSLGISIAGGVGSPLGDVP 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB0 IFIAMMHPTGVAAQTQKLRVGDRIVTICGTSTEGMTHTQAVNLLKNASGSIEMQVVAGGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IFIAMMHPTGVAAQTQKLRVGDRIVTICGTSTEGMTHTQAVNLLKNASGSIEMQVVAGGD 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KB0 VSVVTGHQQEPASSSLSFTGLTSSSIFQDDLGPPQCKSITLERGPDGLGFSIVGGYGSPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VSVVTGHQQEPASSSLSFTGLTSSSIFQDDLGPPQCKSITLERGPDGLGFSIVGGYGSPH 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KB0 GDLPIYVKTVFAKGAASEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GDLPIYVKTVFAKGAASEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMVL 1990 2000 2010 2020 2030 2040 pF1KB0 S : XP_006 S >>NP_003820 (OMIM: 603785,615219) multiple PDZ domain pr (2041 aa) initn: 13162 init1: 13162 opt: 13162 Z-score: 8969.1 bits: 1673.2 E(85289): 0 Smith-Waterman score: 13162; 100.0% identity (100.0% similar) in 2041 aa overlap (1-2041:1-2041) 10 20 30 40 50 60 pF1KB0 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB0 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB0 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB0 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB0 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKVSEGSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKVSEGSLS 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB0 SFTFPLSGSSTSESLESSSKKNALASEIQGLRTVEMKKGPTDSLGISIAGGVGSPLGDVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 SFTFPLSGSSTSESLESSSKKNALASEIQGLRTVEMKKGPTDSLGISIAGGVGSPLGDVP 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB0 IFIAMMHPTGVAAQTQKLRVGDRIVTICGTSTEGMTHTQAVNLLKNASGSIEMQVVAGGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 IFIAMMHPTGVAAQTQKLRVGDRIVTICGTSTEGMTHTQAVNLLKNASGSIEMQVVAGGD 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KB0 VSVVTGHQQEPASSSLSFTGLTSSSIFQDDLGPPQCKSITLERGPDGLGFSIVGGYGSPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VSVVTGHQQEPASSSLSFTGLTSSSIFQDDLGPPQCKSITLERGPDGLGFSIVGGYGSPH 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KB0 GDLPIYVKTVFAKGAASEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 GDLPIYVKTVFAKGAASEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMVL 1990 2000 2010 2020 2030 2040 pF1KB0 S : NP_003 S >>XP_016870741 (OMIM: 603785,615219) PREDICTED: multiple (2042 aa) initn: 12229 init1: 10671 opt: 12155 Z-score: 8283.7 bits: 1546.3 E(85289): 0 Smith-Waterman score: 12835; 97.2% identity (97.2% similar) in 2070 aa overlap (1-2041:1-2042) 10 20 30 40 50 60 pF1KB0 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB0 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB0 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV ::::::::::::::::::::::::::::::: : XP_016 PIIPGCETTIEISKGRTGLGLSIVGGSDTLL----------------------------V 1630 1640 1650 1690 1700 1710 1720 1730 1740 pF1KB0 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI 1660 1670 1680 1690 1700 1710 1750 1760 1770 1780 1790 pF1KB0 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLK------- ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVT 1720 1730 1740 1750 1760 1770 1800 1810 1820 1830 pF1KB0 ----------------------VSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL :::::::::::::::::::::::::::::::::::::: XP_016 LEVGRIKAGPFHSERRPSQSSQVSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL 1780 1790 1800 1810 1820 1830 1840 1850 1860 1870 1880 1890 pF1KB0 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS 1840 1850 1860 1870 1880 1890 1900 1910 1920 1930 1940 1950 pF1KB0 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL 1900 1910 1920 1930 1940 1950 1960 1970 1980 1990 2000 2010 pF1KB0 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KB0 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS :::::::::::::::::::::::::::::: XP_016 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS 2020 2030 2040 >>XP_006716950 (OMIM: 603785,615219) PREDICTED: multiple (2070 aa) initn: 11829 init1: 11606 opt: 11606 Z-score: 7909.9 bits: 1477.2 E(85289): 0 Smith-Waterman score: 13094; 98.6% identity (98.6% similar) in 2070 aa overlap (1-2041:1-2070) 10 20 30 40 50 60 pF1KB0 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB0 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB0 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB0 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 pF1KB0 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLK------- ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVT 1750 1760 1770 1780 1790 1800 1800 1810 1820 1830 pF1KB0 ----------------------VSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL :::::::::::::::::::::::::::::::::::::: XP_006 LEVGRIKAGPFHSERRPSQSSQVSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL 1810 1820 1830 1840 1850 1860 1840 1850 1860 1870 1880 1890 pF1KB0 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS 1870 1880 1890 1900 1910 1920 1900 1910 1920 1930 1940 1950 pF1KB0 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL 1930 1940 1950 1960 1970 1980 1960 1970 1980 1990 2000 2010 pF1KB0 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV 1990 2000 2010 2020 2030 2040 2020 2030 2040 pF1KB0 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS :::::::::::::::::::::::::::::: XP_006 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS 2050 2060 2070 >>XP_006716948 (OMIM: 603785,615219) PREDICTED: multiple (2070 aa) initn: 11829 init1: 11606 opt: 11606 Z-score: 7909.9 bits: 1477.2 E(85289): 0 Smith-Waterman score: 13094; 98.6% identity (98.6% similar) in 2070 aa overlap (1-2041:1-2070) 10 20 30 40 50 60 pF1KB0 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB0 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB0 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB0 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 pF1KB0 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLK------- ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVT 1750 1760 1770 1780 1790 1800 1800 1810 1820 1830 pF1KB0 ----------------------VSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL :::::::::::::::::::::::::::::::::::::: XP_006 LEVGRIKAGPFHSERRPSQSSQVSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL 1810 1820 1830 1840 1850 1860 1840 1850 1860 1870 1880 1890 pF1KB0 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS 1870 1880 1890 1900 1910 1920 1900 1910 1920 1930 1940 1950 pF1KB0 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL 1930 1940 1950 1960 1970 1980 1960 1970 1980 1990 2000 2010 pF1KB0 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV 1990 2000 2010 2020 2030 2040 2020 2030 2040 pF1KB0 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS :::::::::::::::::::::::::::::: XP_006 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS 2050 2060 2070 >>XP_006716949 (OMIM: 603785,615219) PREDICTED: multiple (2070 aa) initn: 11829 init1: 11606 opt: 11606 Z-score: 7909.9 bits: 1477.2 E(85289): 0 Smith-Waterman score: 13094; 98.6% identity (98.6% similar) in 2070 aa overlap (1-2041:1-2070) 10 20 30 40 50 60 pF1KB0 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB0 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB0 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB0 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 pF1KB0 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLK------- ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVT 1750 1760 1770 1780 1790 1800 1800 1810 1820 1830 pF1KB0 ----------------------VSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL :::::::::::::::::::::::::::::::::::::: XP_006 LEVGRIKAGPFHSERRPSQSSQVSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL 1810 1820 1830 1840 1850 1860 1840 1850 1860 1870 1880 1890 pF1KB0 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS 1870 1880 1890 1900 1910 1920 1900 1910 1920 1930 1940 1950 pF1KB0 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL 1930 1940 1950 1960 1970 1980 1960 1970 1980 1990 2000 2010 pF1KB0 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV 1990 2000 2010 2020 2030 2040 2020 2030 2040 pF1KB0 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS :::::::::::::::::::::::::::::: XP_006 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS 2050 2060 2070 >>NP_001317566 (OMIM: 603785,615219) multiple PDZ domain (2070 aa) initn: 11829 init1: 11606 opt: 11606 Z-score: 7909.9 bits: 1477.2 E(85289): 0 Smith-Waterman score: 13094; 98.6% identity (98.6% similar) in 2070 aa overlap (1-2041:1-2070) 10 20 30 40 50 60 pF1KB0 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB0 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB0 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB0 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB0 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 pF1KB0 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLK------- ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVT 1750 1760 1770 1780 1790 1800 1800 1810 1820 1830 pF1KB0 ----------------------VSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL :::::::::::::::::::::::::::::::::::::: NP_001 LEVGRIKAGPFHSERRPSQSSQVSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL 1810 1820 1830 1840 1850 1860 1840 1850 1860 1870 1880 1890 pF1KB0 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS 1870 1880 1890 1900 1910 1920 1900 1910 1920 1930 1940 1950 pF1KB0 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL 1930 1940 1950 1960 1970 1980 1960 1970 1980 1990 2000 2010 pF1KB0 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV 1990 2000 2010 2020 2030 2040 2020 2030 2040 pF1KB0 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS :::::::::::::::::::::::::::::: NP_001 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS 2050 2060 2070 >>XP_016870747 (OMIM: 603785,615219) PREDICTED: multiple (1461 aa) initn: 9478 init1: 9478 opt: 9478 Z-score: 6463.3 bits: 1209.0 E(85289): 0 Smith-Waterman score: 9478; 100.0% identity (100.0% similar) in 1461 aa overlap (1-1461:1-1461) 10 20 30 40 50 60 pF1KB0 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB0 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE ::::::::::::::::::::: XP_016 VCPGNAVEPLPSNSENLQNKE 1450 1460 >>NP_001248335 (OMIM: 603785,615219) multiple PDZ domain (2037 aa) initn: 9815 init1: 8053 opt: 9434 Z-score: 6431.5 bits: 1203.6 E(85289): 0 Smith-Waterman score: 12797; 97.0% identity (97.0% similar) in 2070 aa overlap (1-2041:1-2037) 10 20 30 40 50 60 pF1KB0 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPR------------- 1210 1220 1230 1240 1270 1280 1290 1300 1310 1320 pF1KB0 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI :::::::::::::::::::::::::::::::::::::::: NP_001 --------------------APSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI 1250 1260 1270 1280 1330 1340 1350 1360 1370 1380 pF1KB0 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI 1290 1300 1310 1320 1330 1340 1390 1400 1410 1420 1430 1440 pF1KB0 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA 1350 1360 1370 1380 1390 1400 1450 1460 1470 1480 1490 1500 pF1KB0 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE 1410 1420 1430 1440 1450 1460 1510 1520 1530 1540 1550 1560 pF1KB0 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI 1470 1480 1490 1500 1510 1520 1570 1580 1590 1600 1610 1620 pF1KB0 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC 1530 1540 1550 1560 1570 1580 1630 1640 1650 1660 1670 1680 pF1KB0 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV 1590 1600 1610 1620 1630 1640 1690 1700 1710 1720 1730 1740 pF1KB0 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI 1650 1660 1670 1680 1690 1700 1750 1760 1770 1780 1790 pF1KB0 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLK------- ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVT 1710 1720 1730 1740 1750 1760 1800 1810 1820 1830 pF1KB0 ----------------------VSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL :::::::::::::::::::::::::::::::::::::: NP_001 LEVGRIKAGPFHSERRPSQSSQVSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL 1770 1780 1790 1800 1810 1820 1840 1850 1860 1870 1880 1890 pF1KB0 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS 1830 1840 1850 1860 1870 1880 1900 1910 1920 1930 1940 1950 pF1KB0 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL 1890 1900 1910 1920 1930 1940 1960 1970 1980 1990 2000 2010 pF1KB0 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV 1950 1960 1970 1980 1990 2000 2020 2030 2040 pF1KB0 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS :::::::::::::::::::::::::::::: NP_001 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS 2010 2020 2030 >>XP_006716952 (OMIM: 603785,615219) PREDICTED: multiple (2037 aa) initn: 9815 init1: 8053 opt: 9434 Z-score: 6431.5 bits: 1203.6 E(85289): 0 Smith-Waterman score: 12797; 97.0% identity (97.0% similar) in 2070 aa overlap (1-2041:1-2037) 10 20 30 40 50 60 pF1KB0 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP ::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPR------------- 1210 1220 1230 1240 1270 1280 1290 1300 1310 1320 pF1KB0 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI :::::::::::::::::::::::::::::::::::::::: XP_006 --------------------APSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI 1250 1260 1270 1280 1330 1340 1350 1360 1370 1380 pF1KB0 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI 1290 1300 1310 1320 1330 1340 1390 1400 1410 1420 1430 1440 pF1KB0 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA 1350 1360 1370 1380 1390 1400 1450 1460 1470 1480 1490 1500 pF1KB0 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE 1410 1420 1430 1440 1450 1460 1510 1520 1530 1540 1550 1560 pF1KB0 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI 1470 1480 1490 1500 1510 1520 1570 1580 1590 1600 1610 1620 pF1KB0 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC 1530 1540 1550 1560 1570 1580 1630 1640 1650 1660 1670 1680 pF1KB0 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV 1590 1600 1610 1620 1630 1640 1690 1700 1710 1720 1730 1740 pF1KB0 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI 1650 1660 1670 1680 1690 1700 1750 1760 1770 1780 1790 pF1KB0 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLK------- ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVT 1710 1720 1730 1740 1750 1760 1800 1810 1820 1830 pF1KB0 ----------------------VSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL :::::::::::::::::::::::::::::::::::::: XP_006 LEVGRIKAGPFHSERRPSQSSQVSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL 1770 1780 1790 1800 1810 1820 1840 1850 1860 1870 1880 1890 pF1KB0 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS 1830 1840 1850 1860 1870 1880 1900 1910 1920 1930 1940 1950 pF1KB0 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL 1890 1900 1910 1920 1930 1940 1960 1970 1980 1990 2000 2010 pF1KB0 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV 1950 1960 1970 1980 1990 2000 2020 2030 2040 pF1KB0 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS :::::::::::::::::::::::::::::: XP_006 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS 2010 2020 2030 2041 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 22:37:02 2016 done: Wed Nov 2 22:37:06 2016 Total Scan time: 21.150 Total Display time: 1.510 Function used was FASTA [36.3.4 Apr, 2011]