Result of FASTA (omim) for
pF1KB0067
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0067, 2442 aa
1>>>pF1KB0067 2442 - 2442 aa - 2442 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 19.2154+/-0.000536; mu= -39.8269+/- 0.033
mean_var=901.5913+/-187.803, 0's: 0 Z-trim(124.2): 136 B-trim: 33 in 1/60
Lambda= 0.042714
statistics sampled from 45372 (45542) to 45372 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.787), E-opt: 0.2 (0.534), width: 16
Scan time: 28.550
The best scores are: opt bits E(85289)
NP_004371 (OMIM: 180849,600140) CREB-binding prote (2442) 16860 1056.4 0
XP_016878433 (OMIM: 180849,600140) PREDICTED: CREB (2440) 16831 1054.6 0
XP_011520683 (OMIM: 180849,600140) PREDICTED: CREB (2191) 15122 949.3 0
NP_001073315 (OMIM: 180849,600140) CREB-binding pr (2404) 13906 874.4 0
XP_005255181 (OMIM: 180849,600140) PREDICTED: CREB (2427) 12110 763.7 0
XP_005255182 (OMIM: 180849,600140) PREDICTED: CREB (2303) 10446 661.2 4.5e-188
XP_006720911 (OMIM: 180849,600140) PREDICTED: CREB (2355) 9420 597.9 4.9e-169
XP_011520684 (OMIM: 180849,600140) PREDICTED: CREB (1286) 8701 553.5 6.5e-156
NP_001420 (OMIM: 114500,180849,602700,613684) hist (2414) 6812 437.2 1.2e-120
XP_006724228 (OMIM: 114500,180849,602700,613684) P (2388) 6677 428.9 3.8e-118
>>NP_004371 (OMIM: 180849,600140) CREB-binding protein i (2442 aa)
initn: 16860 init1: 16860 opt: 16860 Z-score: 5633.3 bits: 1056.4 E(85289): 0
Smith-Waterman score: 16860; 100.0% identity (100.0% similar) in 2442 aa overlap (1-2442:1-2442)
10 20 30 40 50 60
pF1KB0 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB0 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB0 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB0 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB0 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KB0 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KB0 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KB0 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KB0 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KB0 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KB0 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KB0 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KB0 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KB0 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KB0 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KB0 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KB0 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440
pF1KB0 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
::::::::::::::::::::::::::::::::::::::::::
NP_004 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
2410 2420 2430 2440
>>XP_016878433 (OMIM: 180849,600140) PREDICTED: CREB-bin (2440 aa)
initn: 11313 init1: 11313 opt: 16831 Z-score: 5623.6 bits: 1054.6 E(85289): 0
Smith-Waterman score: 16831; 99.9% identity (99.9% similar) in 2442 aa overlap (1-2442:1-2440)
10 20 30 40 50 60
pF1KB0 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::
XP_016 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQ--VPGAALPNPLNMLGPQA
790 800 810 820 830
850 860 870 880 890 900
pF1KB0 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB0 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB0 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB0 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KB0 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KB0 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KB0 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KB0 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KB0 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KB0 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KB0 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KB0 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
1500 1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KB0 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
1560 1570 1580 1590 1600 1610
1630 1640 1650 1660 1670 1680
pF1KB0 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
1620 1630 1640 1650 1660 1670
1690 1700 1710 1720 1730 1740
pF1KB0 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
1680 1690 1700 1710 1720 1730
1750 1760 1770 1780 1790 1800
pF1KB0 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
1740 1750 1760 1770 1780 1790
1810 1820 1830 1840 1850 1860
pF1KB0 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
1800 1810 1820 1830 1840 1850
1870 1880 1890 1900 1910 1920
pF1KB0 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
1860 1870 1880 1890 1900 1910
1930 1940 1950 1960 1970 1980
pF1KB0 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
1920 1930 1940 1950 1960 1970
1990 2000 2010 2020 2030 2040
pF1KB0 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
1980 1990 2000 2010 2020 2030
2050 2060 2070 2080 2090 2100
pF1KB0 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
2040 2050 2060 2070 2080 2090
2110 2120 2130 2140 2150 2160
pF1KB0 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
2100 2110 2120 2130 2140 2150
2170 2180 2190 2200 2210 2220
pF1KB0 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
2160 2170 2180 2190 2200 2210
2230 2240 2250 2260 2270 2280
pF1KB0 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
2220 2230 2240 2250 2260 2270
2290 2300 2310 2320 2330 2340
pF1KB0 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
2280 2290 2300 2310 2320 2330
2350 2360 2370 2380 2390 2400
pF1KB0 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
2340 2350 2360 2370 2380 2390
2410 2420 2430 2440
pF1KB0 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
::::::::::::::::::::::::::::::::::::::::::
XP_016 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
2400 2410 2420 2430 2440
>>XP_011520683 (OMIM: 180849,600140) PREDICTED: CREB-bin (2191 aa)
initn: 15122 init1: 15122 opt: 15122 Z-score: 5055.1 bits: 949.3 E(85289): 0
Smith-Waterman score: 15122; 99.9% identity (99.9% similar) in 2180 aa overlap (263-2442:12-2191)
240 250 260 270 280 290
pF1KB0 GASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATG
: .::::::::::::::::::::::::::
XP_011 MLSYPEWTCWRGSHQMGITGNTSPFGQPFSQAGGQPMGATG
10 20 30 40
300 310 320 330 340 350
pF1KB0 VNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRK
50 60 70 80 90 100
360 370 380 390 400 410
pF1KB0 LIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASS
110 120 130 140 150 160
420 430 440 450 460 470
pF1KB0 RQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSN
170 180 190 200 210 220
480 490 500 510 520 530
pF1KB0 PNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIP
230 240 250 260 270 280
540 550 560 570 580 590
pF1KB0 AGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGW
290 300 310 320 330 340
600 610 620 630 640 650
pF1KB0 HEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYH
350 360 370 380 390 400
660 670 680 690 700 710
pF1KB0 LLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPV
410 420 430 440 450 460
720 730 740 750 760 770
pF1KB0 NRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQP
470 480 490 500 510 520
780 790 800 810 820 830
pF1KB0 PNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNP
530 540 550 560 570 580
840 850 860 870 880 890
pF1KB0 LNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPV
590 600 610 620 630 640
900 910 920 930 940 950
pF1KB0 SSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPV
650 660 670 680 690 700
960 970 980 990 1000 1010
pF1KB0 HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGE
710 720 730 740 750 760
1020 1030 1040 1050 1060 1070
pF1KB0 SKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTAS
770 780 790 800 810 820
1080 1090 1100 1110 1120 1130
pF1KB0 QSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNP
830 840 850 860 870 880
1140 1150 1160 1170 1180 1190
pF1KB0 MDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPV
890 900 910 920 930 940
1200 1210 1220 1230 1240 1250
pF1KB0 MQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLG
950 960 970 980 990 1000
1260 1270 1280 1290 1300 1310
pF1KB0 DDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCL
1010 1020 1030 1040 1050 1060
1320 1330 1340 1350 1360 1370
pF1KB0 KKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVK
1070 1080 1090 1100 1110 1120
1380 1390 1400 1410 1420 1430
pF1KB0 PGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYIS
1130 1140 1150 1160 1170 1180
1440 1450 1460 1470 1480 1490
pF1KB0 YLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQK
1190 1200 1210 1220 1230 1240
1500 1510 1520 1530 1540 1550
pF1KB0 IPKPKRLQEWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPKPKRLQEWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEES
1250 1260 1270 1280 1290 1300
1560 1570 1580 1590 1600 1610
pF1KB0 IKELEQEEEERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKELEQEEEERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPN
1310 1320 1330 1340 1350 1360
1620 1630 1640 1650 1660 1670
pF1KB0 VSNDLSQKLYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSNDLSQKLYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLAR
1370 1380 1390 1400 1410 1420
1680 1690 1700 1710 1720 1730
pF1KB0 DKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINC
1430 1440 1450 1460 1470 1480
1740 1750 1760 1770 1780 1790
pF1KB0 YNTKSHAHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YNTKSHAHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSL
1490 1500 1510 1520 1530 1540
1800 1810 1820 1830 1840 1850
pF1KB0 PSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQ
1550 1560 1570 1580 1590 1600
1860 1870 1880 1890 1900 1910
pF1KB0 QQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPS
1610 1620 1630 1640 1650 1660
1920 1930 1940 1950 1960 1970
pF1KB0 PVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHL
1670 1680 1690 1700 1710 1720
1980 1990 2000 2010 2020 2030
pF1KB0 YRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPM
1730 1740 1750 1760 1770 1780
2040 2050 2060 2070 2080 2090
pF1KB0 PGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKS
1790 1800 1810 1820 1830 1840
2100 2110 2120 2130 2140 2150
pF1KB0 NPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRP
1850 1860 1870 1880 1890 1900
2160 2170 2180 2190 2200 2210
pF1KB0 GVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQ
1910 1920 1930 1940 1950 1960
2220 2230 2240 2250 2260 2270
pF1KB0 QQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLG
1970 1980 1990 2000 2010 2020
2280 2290 2300 2310 2320 2330
pF1KB0 QMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPG
2030 2040 2050 2060 2070 2080
2340 2350 2360 2370 2380 2390
pF1KB0 QQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMA
2090 2100 2110 2120 2130 2140
2400 2410 2420 2430 2440
pF1KB0 SSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
2150 2160 2170 2180 2190
>>NP_001073315 (OMIM: 180849,600140) CREB-binding protei (2404 aa)
initn: 13889 init1: 13889 opt: 13906 Z-score: 4649.6 bits: 874.4 E(85289): 0
Smith-Waterman score: 16485; 98.4% identity (98.4% similar) in 2442 aa overlap (1-2442:1-2404)
10 20 30 40 50 60
pF1KB0 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
:::::::::::::::::::::::::::::::::::::::::::::.
NP_001 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQA--------------
370 380 390 400
430 440 450 460 470 480
pF1KB0 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
::::::::::::::::::::::::::::::::::::
NP_001 ------------------------ILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
410 420 430 440
490 500 510 520 530 540
pF1KB0 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
450 460 470 480 490 500
550 560 570 580 590 600
pF1KB0 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
510 520 530 540 550 560
610 620 630 640 650 660
pF1KB0 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
570 580 590 600 610 620
670 680 690 700 710 720
pF1KB0 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
630 640 650 660 670 680
730 740 750 760 770 780
pF1KB0 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
690 700 710 720 730 740
790 800 810 820 830 840
pF1KB0 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
750 760 770 780 790 800
850 860 870 880 890 900
pF1KB0 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
810 820 830 840 850 860
910 920 930 940 950 960
pF1KB0 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KB0 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
930 940 950 960 970 980
1030 1040 1050 1060 1070 1080
pF1KB0 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
990 1000 1010 1020 1030 1040
1090 1100 1110 1120 1130 1140
pF1KB0 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
1050 1060 1070 1080 1090 1100
1150 1160 1170 1180 1190 1200
pF1KB0 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
1110 1120 1130 1140 1150 1160
1210 1220 1230 1240 1250 1260
pF1KB0 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
1170 1180 1190 1200 1210 1220
1270 1280 1290 1300 1310 1320
pF1KB0 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
1230 1240 1250 1260 1270 1280
1330 1340 1350 1360 1370 1380
pF1KB0 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
1290 1300 1310 1320 1330 1340
1390 1400 1410 1420 1430 1440
pF1KB0 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
1350 1360 1370 1380 1390 1400
1450 1460 1470 1480 1490 1500
pF1KB0 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
1410 1420 1430 1440 1450 1460
1510 1520 1530 1540 1550 1560
pF1KB0 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
1470 1480 1490 1500 1510 1520
1570 1580 1590 1600 1610 1620
pF1KB0 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
1530 1540 1550 1560 1570 1580
1630 1640 1650 1660 1670 1680
pF1KB0 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
1590 1600 1610 1620 1630 1640
1690 1700 1710 1720 1730 1740
pF1KB0 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
1650 1660 1670 1680 1690 1700
1750 1760 1770 1780 1790 1800
pF1KB0 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
1710 1720 1730 1740 1750 1760
1810 1820 1830 1840 1850 1860
pF1KB0 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
1770 1780 1790 1800 1810 1820
1870 1880 1890 1900 1910 1920
pF1KB0 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
1830 1840 1850 1860 1870 1880
1930 1940 1950 1960 1970 1980
pF1KB0 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
1890 1900 1910 1920 1930 1940
1990 2000 2010 2020 2030 2040
pF1KB0 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
1950 1960 1970 1980 1990 2000
2050 2060 2070 2080 2090 2100
pF1KB0 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
2010 2020 2030 2040 2050 2060
2110 2120 2130 2140 2150 2160
pF1KB0 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
2070 2080 2090 2100 2110 2120
2170 2180 2190 2200 2210 2220
pF1KB0 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
2130 2140 2150 2160 2170 2180
2230 2240 2250 2260 2270 2280
pF1KB0 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
2190 2200 2210 2220 2230 2240
2290 2300 2310 2320 2330 2340
pF1KB0 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
2250 2260 2270 2280 2290 2300
2350 2360 2370 2380 2390 2400
pF1KB0 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
2310 2320 2330 2340 2350 2360
2410 2420 2430 2440
pF1KB0 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
::::::::::::::::::::::::::::::::::::::::::
NP_001 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
2370 2380 2390 2400
>>XP_005255181 (OMIM: 180849,600140) PREDICTED: CREB-bin (2427 aa)
initn: 16738 init1: 12021 opt: 12110 Z-score: 4051.4 bits: 763.7 E(85289): 0
Smith-Waterman score: 16711; 99.3% identity (99.3% similar) in 2442 aa overlap (1-2442:1-2427)
10 20 30 40 50 60
pF1KB0 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
::::::::::::::::::::::::::::::::::::::::::::
XP_005 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPR---------------
670 680 690 700
730 740 750 760 770 780
pF1KB0 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
710 720 730 740 750 760
790 800 810 820 830 840
pF1KB0 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
770 780 790 800 810 820
850 860 870 880 890 900
pF1KB0 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
830 840 850 860 870 880
910 920 930 940 950 960
pF1KB0 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KB0 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KB0 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KB0 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KB0 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KB0 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KB0 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
pF1KB0 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
1310 1320 1330 1340 1350 1360
1390 1400 1410 1420 1430 1440
pF1KB0 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
1370 1380 1390 1400 1410 1420
1450 1460 1470 1480 1490 1500
pF1KB0 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
1430 1440 1450 1460 1470 1480
1510 1520 1530 1540 1550 1560
pF1KB0 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
1490 1500 1510 1520 1530 1540
1570 1580 1590 1600 1610 1620
pF1KB0 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
1550 1560 1570 1580 1590 1600
1630 1640 1650 1660 1670 1680
pF1KB0 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
1610 1620 1630 1640 1650 1660
1690 1700 1710 1720 1730 1740
pF1KB0 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
1670 1680 1690 1700 1710 1720
1750 1760 1770 1780 1790 1800
pF1KB0 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
1730 1740 1750 1760 1770 1780
1810 1820 1830 1840 1850 1860
pF1KB0 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
1790 1800 1810 1820 1830 1840
1870 1880 1890 1900 1910 1920
pF1KB0 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
1850 1860 1870 1880 1890 1900
1930 1940 1950 1960 1970 1980
pF1KB0 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
1910 1920 1930 1940 1950 1960
1990 2000 2010 2020 2030 2040
pF1KB0 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
1970 1980 1990 2000 2010 2020
2050 2060 2070 2080 2090 2100
pF1KB0 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
2030 2040 2050 2060 2070 2080
2110 2120 2130 2140 2150 2160
pF1KB0 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
2090 2100 2110 2120 2130 2140
2170 2180 2190 2200 2210 2220
pF1KB0 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
2150 2160 2170 2180 2190 2200
2230 2240 2250 2260 2270 2280
pF1KB0 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
2210 2220 2230 2240 2250 2260
2290 2300 2310 2320 2330 2340
pF1KB0 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
2270 2280 2290 2300 2310 2320
2350 2360 2370 2380 2390 2400
pF1KB0 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
2330 2340 2350 2360 2370 2380
2410 2420 2430 2440
pF1KB0 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
::::::::::::::::::::::::::::::::::::::::::
XP_005 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
2390 2400 2410 2420
>>XP_005255182 (OMIM: 180849,600140) PREDICTED: CREB-bin (2303 aa)
initn: 10348 init1: 10348 opt: 10446 Z-score: 3497.5 bits: 661.2 E(85289): 4.5e-188
Smith-Waterman score: 15593; 94.3% identity (94.3% similar) in 2442 aa overlap (1-2442:1-2303)
10 20 30 40 50 60
pF1KB0 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
:::::::::::::::::::::::::::::::::::::::::
XP_005 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQ-------------------
790 800 810 820
850 860 870 880 890 900
pF1KB0 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
XP_005 ------------------------------------------------------------
910 920 930 940 950 960
pF1KB0 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
XP_005 ------------------------------------------------------------
970 980 990 1000 1010 1020
pF1KB0 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
830 840 850 860 870 880
1030 1040 1050 1060 1070 1080
pF1KB0 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
890 900 910 920 930 940
1090 1100 1110 1120 1130 1140
pF1KB0 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
950 960 970 980 990 1000
1150 1160 1170 1180 1190 1200
pF1KB0 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
1010 1020 1030 1040 1050 1060
1210 1220 1230 1240 1250 1260
pF1KB0 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
1070 1080 1090 1100 1110 1120
1270 1280 1290 1300 1310 1320
pF1KB0 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
1130 1140 1150 1160 1170 1180
1330 1340 1350 1360 1370 1380
pF1KB0 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
1190 1200 1210 1220 1230 1240
1390 1400 1410 1420 1430 1440
pF1KB0 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
1250 1260 1270 1280 1290 1300
1450 1460 1470 1480 1490 1500
pF1KB0 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
1310 1320 1330 1340 1350 1360
1510 1520 1530 1540 1550 1560
pF1KB0 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
1370 1380 1390 1400 1410 1420
1570 1580 1590 1600 1610 1620
pF1KB0 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
1430 1440 1450 1460 1470 1480
1630 1640 1650 1660 1670 1680
pF1KB0 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
1490 1500 1510 1520 1530 1540
1690 1700 1710 1720 1730 1740
pF1KB0 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
1550 1560 1570 1580 1590 1600
1750 1760 1770 1780 1790 1800
pF1KB0 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
1610 1620 1630 1640 1650 1660
1810 1820 1830 1840 1850 1860
pF1KB0 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
1670 1680 1690 1700 1710 1720
1870 1880 1890 1900 1910 1920
pF1KB0 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
1730 1740 1750 1760 1770 1780
1930 1940 1950 1960 1970 1980
pF1KB0 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
1790 1800 1810 1820 1830 1840
1990 2000 2010 2020 2030 2040
pF1KB0 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
1850 1860 1870 1880 1890 1900
2050 2060 2070 2080 2090 2100
pF1KB0 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
1910 1920 1930 1940 1950 1960
2110 2120 2130 2140 2150 2160
pF1KB0 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
1970 1980 1990 2000 2010 2020
2170 2180 2190 2200 2210 2220
pF1KB0 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
2030 2040 2050 2060 2070 2080
2230 2240 2250 2260 2270 2280
pF1KB0 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
2090 2100 2110 2120 2130 2140
2290 2300 2310 2320 2330 2340
pF1KB0 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
2150 2160 2170 2180 2190 2200
2350 2360 2370 2380 2390 2400
pF1KB0 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
2210 2220 2230 2240 2250 2260
2410 2420 2430 2440
pF1KB0 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
::::::::::::::::::::::::::::::::::::::::::
XP_005 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
2270 2280 2290 2300
>>XP_006720911 (OMIM: 180849,600140) PREDICTED: CREB-bin (2355 aa)
initn: 9698 init1: 9395 opt: 9420 Z-score: 3155.7 bits: 597.9 E(85289): 4.9e-169
Smith-Waterman score: 16069; 96.4% identity (96.4% similar) in 2442 aa overlap (1-2442:1-2355)
10 20 30 40 50 60
pF1KB0 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSR--
1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KB0 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
XP_006 ------------------------------------------------------------
1450 1460 1470 1480 1490 1500
pF1KB0 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
:::::::::::::::::::::::::::::::::::
XP_006 -------------------------YVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
1380 1390 1400 1410
1510 1520 1530 1540 1550 1560
pF1KB0 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
1420 1430 1440 1450 1460 1470
1570 1580 1590 1600 1610 1620
pF1KB0 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
1480 1490 1500 1510 1520 1530
1630 1640 1650 1660 1670 1680
pF1KB0 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
1540 1550 1560 1570 1580 1590
1690 1700 1710 1720 1730 1740
pF1KB0 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
1600 1610 1620 1630 1640 1650
1750 1760 1770 1780 1790 1800
pF1KB0 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
1660 1670 1680 1690 1700 1710
1810 1820 1830 1840 1850 1860
pF1KB0 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
1720 1730 1740 1750 1760 1770
1870 1880 1890 1900 1910 1920
pF1KB0 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
1780 1790 1800 1810 1820 1830
1930 1940 1950 1960 1970 1980
pF1KB0 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
1840 1850 1860 1870 1880 1890
1990 2000 2010 2020 2030 2040
pF1KB0 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
1900 1910 1920 1930 1940 1950
2050 2060 2070 2080 2090 2100
pF1KB0 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
1960 1970 1980 1990 2000 2010
2110 2120 2130 2140 2150 2160
pF1KB0 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
2020 2030 2040 2050 2060 2070
2170 2180 2190 2200 2210 2220
pF1KB0 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
2080 2090 2100 2110 2120 2130
2230 2240 2250 2260 2270 2280
pF1KB0 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
2140 2150 2160 2170 2180 2190
2290 2300 2310 2320 2330 2340
pF1KB0 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
2200 2210 2220 2230 2240 2250
2350 2360 2370 2380 2390 2400
pF1KB0 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
2260 2270 2280 2290 2300 2310
2410 2420 2430 2440
pF1KB0 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
::::::::::::::::::::::::::::::::::::::::::
XP_006 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
2320 2330 2340 2350
>>XP_011520684 (OMIM: 180849,600140) PREDICTED: CREB-bin (1286 aa)
initn: 8701 init1: 8701 opt: 8701 Z-score: 2920.1 bits: 553.5 E(85289): 6.5e-156
Smith-Waterman score: 8701; 99.7% identity (99.8% similar) in 1285 aa overlap (1-1285:1-1285)
10 20 30 40 50 60
pF1KB0 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
::::::::::::::::::: . ::
XP_011 TISKDQFEKKKNDTLDPEPEIGRKEE
1270 1280
>>NP_001420 (OMIM: 114500,180849,602700,613684) histone (2414 aa)
initn: 7325 init1: 3547 opt: 6812 Z-score: 2287.0 bits: 437.2 E(85289): 1.2e-120
Smith-Waterman score: 9748; 60.9% identity (78.5% similar) in 2517 aa overlap (1-2431:1-2400)
10 20 30 40 50
pF1KB0 MAENLLD-GPPNPKRAKLSSPGFSAN--DSTDFGSLFDLENDLPDELIPNGGELGLLNSG
::::... :::. :: :::::..::. :.::::::::::.::::::: :. :::: :.:
NP_001 MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELI-NSTELGLTNGG
10 20 30 40 50
60 70 80 90 100
pF1KB0 N---------LVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPN
. .: ::::::::::::::.::. ..: :.:. : : .:.: .
NP_001 DINQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGG-----P---GQVMASQAQQS
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB0 SANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPAT
: ... ...: :::..:. ..:.. . .::::. . .:. .:. .:
NP_001 SPGLGLINSMVKSPMTQAGLTSPNM---GMGTSGPNQGPTQS--------TGMMNSPVNQ
120 130 140 150 160
170 180 190 200 210 220
pF1KB0 SQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPT
: . :::..: ::.: ...:.... . ::::::.:: :::: .: ::.
NP_001 PAMGMNTGMNAGMN---PGMLAAGNGQGIMPN------QVMNGSIGA-GRGR-QNMQYPN
170 180 190 200
230 240 250 260 270 280
pF1KB0 PAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPM
:.: :.....:.: : : :::: :..:: : :::. .: .:.:.:..: :: .
NP_001 PGM-GSAGNLLTEPLQQGSPQMGGQTGLRGPQP---LKMGMMNNPNPYGSPYTQNPGQQI
210 220 230 240 250 260
290 300 310 320 330 340
pF1KB0 GATGVNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQ-----MQTSVGIVPT-QAIAT
::.:.. :. .: . :.: : : : . ..:::.: .: ..:. :....
NP_001 GASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPAPQVQQPGLVTPVAQGMGS
270 280 290 300 310 320
350 360 370 380 390 400
pF1KB0 GP-TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAG
: :::::::::::::::::::::::::::::::::: :.::::::::::::::::::.:
NP_001 GAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSG
330 340 350 360 370 380
410 420 430 440 450 460
pF1KB0 KACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTIL-GSPASGIQNTIGSV
:.:::::::::::::::::::::::::::::::::.:::::: :: :.:. :. : .:.
NP_001 KSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPV-GLGNP-SSL
390 400 410 420 430 440
470 480 490 500 510
pF1KB0 GTGQQNATSLSNPNPIDPSSMQRAYAALGLPY-MNQPQTQLQPQVPGQQPAQP-QTHQQM
:.:::.: .::. . :::::..:::::::::: .:: :: : :. .:: :: :. : :
NP_001 GVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMPTQPQVQAKNQQNQQPGQSPQGM
450 460 470 480 490 500
520 530 540 550 560 570
pF1KB0 RTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIP
: .. .. .::.. ::. . : :.:.:.: : ..... ::.: :..... .:. .:
NP_001 RPMSNMSASPMGV-NGGVGV--QTPSLLSDSMLHSAINSQNPMM---SENASVPSLGPMP
510 520 530 540 550
580 590 600 610 620 630
pF1KB0 TAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEG
::: ::.::.:: ::: .:::::.:::::::::::::::::::::::::::::::.::::
NP_001 TAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEG
560 570 580 590 600 610
640 650 660 670 680 690
pF1KB0 DMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQP-PVIPQ
:::::::.: ::::::::::::::::::::::.::.::..: : .. . .: : . :
NP_001 DMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQ
620 630 640 650 660 670
700 710 720 730 740 750
pF1KB0 AQPVRPPNGPLSLP-VNRMQV-SQGMNSFNPMS----LGNVQLPQAPMGPRAASPMNHSV
:: :::: : . : .: .: : ..:.: .:.... : :. :: . :..:
NP_001 PQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHG
680 690 700 710 720 730
760 770 780 790 800
pF1KB0 QMNSMGSV-PGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSS-GAMSVG
:. . :.. : :. .: :: :: : :.:::::.::::.. .. ..
NP_001 QLAQPGALNPPMGYGP-RMQQPSN---------------QGQFLPQTQFPSQGMNVTNIP
740 750 760 770 780
810 820 830 840 850 860
pF1KB0 MGQPPAQTGVSQGQVPGAALP--NPLNMLGPQASQLPCPPVTQSPLH---PTPPPASTAA
.. .:. :::.:. ... : .:. : :.:.. :: . : :: :.: :. : .
NP_001 LAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPT
790 800 810 820 830 840
870 880 890 900 910 920
pF1KB0 GM---PSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAA
::. ::. : : :. :: :. : . ..:. : : ..:. :: :: .
NP_001 PHHTPPSIGAQQPPATTIPAPV-PTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPS
850 860 870 880 890 900
930 940 950 960 970
pF1KB0 AQAQVTP-QPQTPVQPPSVATPQSSQQQPT-PVHAQPPGTPLSQAAASIDNRVPTPSSVA
: . ::: :: : . .: :: :. :.::::: :.::...: .: :..
NP_001 LPAAPSADQPQQ--QPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTS
910 920 930 940 950
980 990 1000 1010 1020 1030
pF1KB0 SAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIA
:.:.::: . : :.: :.. : .:.:... .: ::.. :. .
NP_001 STEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADT--QP------EDIS-------ESKVE
960 970 980 990 1000
1040 1050 1060 1070 1080 1090
pF1KB0 EQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLE
. : : :..:.. :.:.:.::::.. :......: .:.: .::::::::::::::::::
NP_001 DCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLE
1010 1020 1030 1040 1050 1060
1100 1110 1120 1130 1140 1150
pF1KB0 ALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWL
:::::::::::::::::::::::::::::::.:::::::::::::::::::::::::.::
NP_001 ALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWL
1070 1080 1090 1100 1110 1120
1160 1170 1180 1190 1200 1210
pF1KB0 MFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLC
:::::::::::::::::.::::.::::::::::::::::::::: :::::::::::::::
NP_001 MFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLC
1130 1140 1150 1160 1170 1180
1220 1230 1240 1250 1260 1270
pF1KB0 TIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEP
::::::.:::::::::::::::.:::::.:.::::::::::::.:.:: :.::::::::
NP_001 TIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPEL
1190 1200 1210 1220 1230 1240
1280 1290 1300 1310 1320 1330
pF1KB0 FVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLE
::.: :::::::::::::..::::.:::::.::::..: ::::::::::: .::::. ::
NP_001 FVECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFLE
1250 1260 1270 1280 1290 1300
1340 1350 1360 1370 1380 1390
pF1KB0 DRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAF
.::: :::::::::.::: :::: .::::::::::::.::::::::.:::::::::::::
NP_001 NRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAF
1310 1320 1330 1340 1350 1360
1400 1410 1420 1430 1440 1450
pF1KB0 EEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEILIGYLE
:::::::.:::::::::::::::::: ::::::::::.:::::.::::::::::::::::
NP_001 EEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLE
1370 1380 1390 1400 1410 1420
1460 1470 1480 1490 1500 1510
pF1KB0 YVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIIHDY
:::::::.::::::::::::::::::::::::::::::::::::::::::: .:::.:::
NP_001 YVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDY
1430 1440 1450 1460 1470 1480
1520 1530 1540 1550 1560 1570
pF1KB0 KDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEESTAASETTEGSQ
:::::::::::::::::::::::::::::::::::::::::::::.::.:. .:.:. ..
NP_001 KDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENTS-NESTDVTK
1490 1500 1510 1520 1530 1540
1580 1590 1600 1610 1620 1630
pF1KB0 GDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHA
::::::::::::::.:::::.::.:::::.::::::::::::::::::::::::::.: :
NP_001 GDSKNAKKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIA
1550 1560 1570 1580 1590 1600
1640 1650 1660 1670 1680 1690
pF1KB0 GPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQG
::. :.::::::::::. :::::::::::::::::: :::::::..:::.:::::::::.
NP_001 GPAANSLPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQS
1610 1620 1630 1640 1650 1660
1700 1710 1720 1730 1740 1750
pF1KB0 QDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAHKMVKWGLGLDDEGSSQGEP
:::::::::::::::::::::::::::::::.:::::.: ::: : :::::::...:
NP_001 QDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAA
1670 1680 1690 1700 1710 1720
1760 1770 1780 1790 1800 1810
pF1KB0 QSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVC
..:: .:::::::::::::::::::::::::::::::::::::::::::::::::::.:
NP_001 ATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPIC
1730 1740 1750 1760 1770 1780
1820 1830 1840 1850 1860 1870
pF1KB0 KQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNV--
::::::::::::::::::::::::::::.::::::.::::::::..:::::.:. .:
NP_001 KQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVG
1790 1800 1810 1820 1830 1840
1880 1890 1900 1910 1920 1930
pF1KB0 PQQSLPSPTSAPPGTPT-QQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTG
::.::::: : : ::: :::.::::::: .::::.: . : : . ::: :: :
NP_001 QQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMP---PYLPRTQAAGPVSQG
1850 1860 1870 1880 1890
1940 1950 1960 1970 1980
pF1KB0 KPTSQV--PAPPPPAQPP-----PAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMG
: ..:: :.:: :::: ::::: : ::.: :. :... .:.: . : . :
NP_001 KAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQR--PIQHQM-
1900 1910 1920 1930 1940 1950
1990 2000 2010 2020 2030 2040
pF1KB0 TPGSQMAPVSLNVPRPNQ-VSGPVMPSM-PPGQWQQAP-----LPQ-QQPMPGLPRPVIS
: . :::...: : .. :: . :.: : :. :: : ::: :: . :.:::..
NP_001 PPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMM
1960 1970 1980 1990 2000 2010
2050 2060 2070 2080 2090
pF1KB0 MQAQ-------AAVAGPRMPSVQP--PRSISPSALQDLLRTLKSPSSPQQQQQVLNILKS
:: : : . ...: : ..: .:::.:::::.::::: ::::::.::..
NP_001 SVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHA
2020 2030 2040 2050 2060 2070
2100 2110 2120 2130 2140
pF1KB0 NPQLMAAFIKQRTAKYVANQPGMQP-QPGL-QSQPGMQP-----QPGMHQQPSLQNLNAM
::::.:::::::.:::. ..: : :::. :.:::.:: : :.:..:..::.: :
NP_001 NPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPM
2080 2090 2100 2110 2120 2130
2150 2160 2170 2180 2190
pF1KB0 QAGVPRPGVP---PQQQ---AMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQ
:::: : :.: :::: :::..::.: .: :: :: .: :.:..::::
NP_001 QAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMN-MN--HN----TMPSQFRDILRRQ---
2140 2150 2160 2170 2180
2200 2210 2220 2230 2240 2250
pF1KB0 QQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGS
:..:::::: .. :.. :::.:.::::::: : ::: :::::::.:. .
NP_001 -------QMMQQQQQQGAGPGIGPGMANHNQFQQPQGVG-YPP--QQQQRMQHHM----Q
2190 2200 2210 2220 2230
2260 2270 2280 2290 2300 2310
pF1KB0 SMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQH
.: : ..:::.::. : .:::.. ..: : :::.:::: .::: ::::::::::
NP_001 QMQQ--GNMGQIGQLPQ-ALGAEAGASLQ-AYQQRLLQQQ-----MGSPVQPNPMSPQQH
2240 2250 2260 2270 2280
2320 2330 2340 2350 2360 2370
pF1KB0 MLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQ
:: .: :. :: :::: .::::::::: :: ::::::::::::::::.::::::::::::
NP_001 MLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQ
2290 2300 2310 2320 2330 2340
2380 2390 2400 2410 2420 2430
pF1KB0 TGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNT-PSRSAL----SSELSLVGDTTGDT
:.::::::....:. ..:::...:.:..:: :: . :. . : ...:.: :..
NP_001 TSSPHPGLVAAQANPMEQGHFASPDQNSMLSQLASNPGMANLHGASATDLGLSTDNSDLN
2350 2360 2370 2380 2390 2400
2440
pF1KB0 LEKFVEGL
NP_001 SNLSQSTLDIH
2410
>>XP_006724228 (OMIM: 114500,180849,602700,613684) PREDI (2388 aa)
initn: 7272 init1: 3547 opt: 6677 Z-score: 2242.1 bits: 428.9 E(85289): 3.8e-118
Smith-Waterman score: 9693; 60.7% identity (78.4% similar) in 2511 aa overlap (1-2431:1-2374)
10 20 30 40 50
pF1KB0 MAENLLD-GPPNPKRAKLSSPGFSAN--DSTDFGSLFDLENDLPDELIPNGGELGLLNSG
::::... :::. :: :::::..::. :.::::::::::.::::::: :. :::: :.:
XP_006 MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELI-NSTELGLTNGG
10 20 30 40 50
60 70 80 90 100
pF1KB0 N---------LVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPN
. .: ::::::::::::::.::. ..: :.:. : : .:.: .
XP_006 DINQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGG-----P---GQVMASQAQQS
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB0 SANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPAT
: ... ...: :::..:. ..:.. . .::::. . .:. .:. .:
XP_006 SPGLGLINSMVKSPMTQAGLTSPNM---GMGTSGPNQGPTQS--------TGMMNSPVNQ
120 130 140 150 160
170 180 190 200 210 220
pF1KB0 SQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPT
: . :::..: ::.: ...:.... . ::::::.:: :::: .: ::.
XP_006 PAMGMNTGMNAGMN---PGMLAAGNGQGIMPN------QVMNGSIGA-GRGR-QNMQYPN
170 180 190 200
230 240 250 260 270 280
pF1KB0 PAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPM
:.: :.....:.: : : :::: :..:: : :::. .: .:.:.:..: :: .
XP_006 PGM-GSAGNLLTEPLQQGSPQMGGQTGLRGPQP---LKMGMMNNPNPYGSPYTQNPGQQI
210 220 230 240 250 260
290 300 310 320 330 340
pF1KB0 GATGVNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQ-----MQTSVGIVPT-QAIAT
::.:.. :. .: . :.: : : : . ..:::.: .: ..:. :....
XP_006 GASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPAPQVQQPGLVTPVAQGMGS
270 280 290 300 310 320
350 360 370 380 390 400
pF1KB0 GP-TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAG
: :::::::::::::::::::::::::::::::::: :.::::::::::::::::::.:
XP_006 GAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSG
330 340 350 360 370 380
410 420 430 440 450 460
pF1KB0 KACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTIL-GSPASGIQNTIGSV
:.:::::::::::::::::::::::::::::::::.:::::: :: :.:. :. : .:.
XP_006 KSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPV-GLGNP-SSL
390 400 410 420 430 440
470 480 490 500 510
pF1KB0 GTGQQNATSLSNPNPIDPSSMQRAYAALGLPY-MNQPQTQLQPQVPGQQPAQP-QTHQQM
:.:::.: .::. . :::::..:::::::::: .:: :: : :. .:: :: :. : :
XP_006 GVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMPTQPQVQAKNQQNQQPGQSPQGM
450 460 470 480 490 500
520 530 540 550 560 570
pF1KB0 RTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIP
: .. .. .::.. ::. . : :.:.:.: : ..... ::.: :..... .:. .:
XP_006 RPMSNMSASPMGV-NGGVGV--QTPSLLSDSMLHSAINSQNPMM---SENASVPSLGPMP
510 520 530 540 550
580 590 600 610 620 630
pF1KB0 TAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEG
::: ::.::.:: ::: .:::::.:::::::::::::::::::::::::::::::.::::
XP_006 TAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEG
560 570 580 590 600 610
640 650 660 670 680 690
pF1KB0 DMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQP-PVIPQ
:::::::.: ::::::::::::::::::::::.::.::..: : .. . .: : . :
XP_006 DMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQ
620 630 640 650 660 670
700 710 720 730 740 750
pF1KB0 AQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMG
:: : .....:.:. ::.. : :. :: . :..: :. . :
XP_006 PQP-----G----------MTSSLNQFGQMSMA-----QPPIVPRQTPPLQHHGQLAQPG
680 690 700 710
760 770 780 790 800 810
pF1KB0 SV-PGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSS-GAMSVGMGQPPA
.. : :. .: :: :: : :.:::::.::::.. .. .. .. .
XP_006 ALNPPMGYGP-RMQQPSN---------------QGQFLPQTQFPSQGMNVTNIPLAPSSG
720 730 740 750 760
820 830 840 850 860
pF1KB0 QTGVSQGQVPGAALP--NPLNMLGPQASQLPCPPVTQSPLH---PTPPPASTAAGM---P
:. :::.:. ... : .:. : :.:.. :: . : :: :.: :. : . :
XP_006 QAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPP
770 780 790 800 810 820
870 880 890 900 910 920
pF1KB0 SLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVT
:. ::. : : :. :: :. : . ..:. : : ..:. :: :: . : .
XP_006 SIGAQQPPATTIPAPV-PTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPS
830 840 850 860 870 880
930 940 950 960 970 980
pF1KB0 P-QPQTPVQPPSVATPQSSQQQPT-PVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNS
::: :: : . .: :: :. :.::::: :.::...: .: :..:.:.::
XP_006 ADQPQQ--QPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNS
890 900 910 920 930
990 1000 1010 1020 1030 1040
pF1KB0 QQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEP
: . : :.: :.. : .:.:... .: ::.. :. . . : :
XP_006 QAIAEKQPSQEVKMEAKMEVDQPEPADT--QP------EDIS-------ESKVEDCKMES
940 950 960 970 980
1050 1060 1070 1080 1090 1100
pF1KB0 MEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQD
:..:.. :.:.:.::::.. :......: .:.: .::::::::::::::::::::::::
XP_006 TETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQD
990 1000 1010 1020 1030 1040
1110 1120 1130 1140 1150 1160
pF1KB0 PESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAW
:::::::::::::::::::::::::.:::::::::::::::::::::::::.::::::::
XP_006 PESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAW
1050 1060 1070 1080 1090 1100
1170 1180 1190 1200 1210 1220
pF1KB0 LYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDA
:::::::::::.::::.::::::::::::::::::::: :::::::::::::::::::::
XP_006 LYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDA
1110 1120 1130 1140 1150 1160
1230 1240 1250 1260 1270 1280
pF1KB0 AYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKE
.:::::::::::::::.:::::.:.::::::::::::.:.:: :.:::::::: ::.: :
XP_006 TYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTE
1170 1180 1190 1200 1210 1220
1290 1300 1310 1320 1330 1340
pF1KB0 CGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKF
::::::::::::..::::.:::::.::::..: ::::::::::: .::::. ::.::: :
XP_006 CGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFLENRVNDF
1230 1240 1250 1260 1270 1280
1350 1360 1370 1380 1390 1400
pF1KB0 LRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGV
::::::::.::: :::: .::::::::::::.::::::::.:::::::::::::::::::
XP_006 LRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGV
1290 1300 1310 1320 1330 1340
1410 1420 1430 1440 1450 1460
pF1KB0 DVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLG
:.:::::::::::::::::: ::::::::::.:::::.::::::::::::::::::::::
XP_006 DLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLG
1350 1360 1370 1380 1390 1400
1470 1480 1490 1500 1510 1520
pF1KB0 YVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIIHDYKDIFKQ
:.::::::::::::::::::::::::::::::::::::::::::: .:::.:::::::::
XP_006 YTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQ
1410 1420 1430 1440 1450 1460
1530 1540 1550 1560 1570 1580
pF1KB0 ATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEESTAASETTEGSQGDSKNA
:::::::::::::::::::::::::::::::::::::::.::.:. .:.:. ..::::::
XP_006 ATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENTS-NESTDVTKGDSKNA
1470 1480 1490 1500 1510 1520
1590 1600 1610 1620 1630 1640
pF1KB0 KKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVINT
::::::::.:::::.::.:::::.::::::::::::::::::::::::::.: :::. :.
XP_006 KKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGPAANS
1530 1540 1550 1560 1570 1580
1650 1660 1670 1680 1690 1700
pF1KB0 LPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVY
::::::::::. :::::::::::::::::: :::::::..:::.:::::::::.::::::
XP_006 LPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVY
1590 1600 1610 1620 1630 1640
1710 1720 1730 1740 1750 1760
pF1KB0 TCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAHKMVKWGLGLDDEGSSQGEPQSKSPQ
:::::::::::::::::::::::::.:::::.: ::: : :::::::...: ..::
XP_006 TCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPG
1650 1660 1670 1680 1690 1700
1770 1780 1790 1800 1810 1820
pF1KB0 ESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIAL
.:::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
XP_006 DSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIAL
1710 1720 1730 1740 1750 1760
1830 1840 1850 1860 1870 1880
pF1KB0 CCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNV--PQQSLP
::::::::::::::::::::::.::::::.::::::::..:::::.:. .: ::.::
XP_006 CCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLP
1770 1780 1790 1800 1810 1820
1890 1900 1910 1920 1930 1940
pF1KB0 SPTSAPPGTPT-QQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQV
::: : : ::: :::.::::::: .::::.: . : : . ::: :: :: ..::
XP_006 SPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMP---PYLPRTQAAGPVSQGKAAGQV
1830 1840 1850 1860 1870
1950 1960 1970 1980 1990
pF1KB0 --PAPPPPAQPP-----PAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQM
:.:: :::: ::::: : ::.: :. :... .:.: . : . : : . :
XP_006 TPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQR--PIQHQM-PPMTPM
1880 1890 1900 1910 1920 1930
2000 2010 2020 2030 2040
pF1KB0 APVSLNVPRPNQ-VSGPVMPSM-PPGQWQQAP-----LPQ-QQPMPGLPRPVISMQAQ--
::...: : .. :: . :.: : :. :: : ::: :: . :.:::.. ::
XP_006 APMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHG
1940 1950 1960 1970 1980 1990
2050 2060 2070 2080 2090
pF1KB0 -----AAVAGPRMPSVQP--PRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMA
: : . ...: : ..: .:::.:::::.::::: ::::::.::..::::.:
XP_006 QPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLA
2000 2010 2020 2030 2040 2050
2100 2110 2120 2130 2140 2150
pF1KB0 AFIKQRTAKYVANQPGMQP-QPGL-QSQPGMQP-----QPGMHQQPSLQNLNAMQAGVPR
::::::.:::. ..: : :::. :.:::.:: : :.:..:..::.: ::::: :
XP_006 AFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQR
2060 2070 2080 2090 2100 2110
2160 2170 2180 2190 2200
pF1KB0 PGVP---PQQQ---AMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQ
:.: :::: :::..::.: .: :: :: .: :.:..::::
XP_006 AGLPQQQPQQQLQPPMGGMSPQAQQMN-MN--HN----TMPSQFRDILRRQ---------
2120 2130 2140 2150 2160
2210 2220 2230 2240 2250 2260
pF1KB0 QQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMA
:..:::::: .. :.. :::.:.::::::: : ::: :::::::.:. ..: :
XP_006 -QMMQQQQQQGAGPGIGPGMANHNQFQQPQGVG-YPP--QQQQRMQHHM----QQMQQ--
2170 2180 2190 2200 2210
2270 2280 2290 2300 2310 2320
pF1KB0 AQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQP
..:::.::. : .:::.. ..: : :::.:::: .::: :::::::::::: .:
XP_006 GNMGQIGQLPQ-ALGAEAGASLQ-AYQQRLLQQQ-----MGSPVQPNPMSPQQHMLPNQA
2220 2230 2240 2250 2260
2330 2340 2350 2360 2370 2380
pF1KB0 QASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHP
:. :: :::: .::::::::: :: ::::::::::::::::.:::::::::::::.::::
XP_006 QSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHP
2270 2280 2290 2300 2310 2320
2390 2400 2410 2420 2430 2440
pF1KB0 GLAVTMASSIDQGHLGNPEQSAMLPQLNT-PSRSAL----SSELSLVGDTTGDTLEKFVE
::....:. ..:::...:.:..:: :: . :. . : ...:.: :..
XP_006 GLVAAQANPMEQGHFASPDQNSMLSQLASNPGMANLHGASATDLGLSTDNSDLNSNLSQS
2330 2340 2350 2360 2370 2380
pF1KB0 GL
XP_006 TLDIH
2442 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 20:22:17 2016 done: Sun Nov 6 20:22:21 2016
Total Scan time: 28.550 Total Display time: 2.480
Function used was FASTA [36.3.4 Apr, 2011]