FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0100, 1021 aa 1>>>pF1KB0100 1021 - 1021 aa - 1021 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.8847+/-0.000465; mu= -5.4702+/- 0.028 mean_var=417.9305+/-88.619, 0's: 0 Z-trim(120.1): 657 B-trim: 696 in 1/57 Lambda= 0.062737 statistics sampled from 34195 (34938) to 34195 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.727), E-opt: 0.2 (0.41), width: 16 Scan time: 16.980 The best scores are: opt bits E(85289) XP_011514182 (OMIM: 602757) PREDICTED: ephrin type (1022) 6985 648.0 7.7e-185 NP_004436 (OMIM: 602757) ephrin type-B receptor 6 (1022) 6985 648.0 7.7e-185 XP_006715944 (OMIM: 602757) PREDICTED: ephrin type (1022) 6985 648.0 7.7e-185 XP_011514181 (OMIM: 602757) PREDICTED: ephrin type (1022) 6985 648.0 7.7e-185 XP_011514183 (OMIM: 602757) PREDICTED: ephrin type (1021) 6966 646.3 2.5e-184 NP_001267724 (OMIM: 602757) ephrin type-B receptor ( 729) 5012 469.3 3.5e-131 NP_001267723 (OMIM: 602757) ephrin type-B receptor ( 729) 5012 469.3 3.5e-131 XP_011514184 (OMIM: 602757) PREDICTED: ephrin type ( 991) 3149 300.8 2.5e-80 NP_004432 (OMIM: 600600) ephrin type-B receptor 1 ( 984) 1894 187.2 3.8e-46 NP_004434 (OMIM: 601839) ephrin type-B receptor 3 ( 998) 1806 179.2 9.7e-44 XP_005264773 (OMIM: 179611) PREDICTED: ephrin type ( 918) 1541 155.2 1.5e-36 NP_005224 (OMIM: 179611) ephrin type-A receptor 3 ( 983) 1541 155.2 1.6e-36 XP_005264772 (OMIM: 179611) PREDICTED: ephrin type ( 982) 1534 154.6 2.5e-36 NP_001268695 (OMIM: 600004) ephrin type-A receptor (1016) 1511 152.5 1.1e-35 NP_872272 (OMIM: 600004) ephrin type-A receptor 5 (1015) 1507 152.2 1.4e-35 XP_005246431 (OMIM: 602188) PREDICTED: ephrin type ( 949) 1375 140.2 5.2e-32 XP_016865854 (OMIM: 602190) PREDICTED: ephrin type ( 989) 1295 133.0 8e-30 NP_001275558 (OMIM: 602190) ephrin type-A receptor ( 993) 1273 131.0 3.2e-29 XP_011539272 (OMIM: 176945) PREDICTED: ephrin type ( 930) 1193 123.7 4.6e-27 XP_011539271 (OMIM: 176945) PREDICTED: ephrin type ( 930) 1193 123.7 4.6e-27 XP_011539274 (OMIM: 176945) PREDICTED: ephrin type ( 930) 1193 123.7 4.6e-27 XP_011539275 (OMIM: 176945) PREDICTED: ephrin type ( 930) 1193 123.7 4.6e-27 NP_065387 (OMIM: 176945) ephrin type-A receptor 8 (1005) 1193 123.8 4.9e-27 XP_016867305 (OMIM: 600011) PREDICTED: ephrin type (1005) 1185 123.0 8.1e-27 NP_004435 (OMIM: 600011) ephrin type-B receptor 4 ( 987) 1173 121.9 1.7e-26 XP_016861357 (OMIM: 600600) PREDICTED: ephrin type (1016) 1160 120.8 3.9e-26 XP_016861356 (OMIM: 600600) PREDICTED: ephrin type (1032) 1160 120.8 3.9e-26 XP_016861355 (OMIM: 600600) PREDICTED: ephrin type (1038) 1160 120.8 4e-26 NP_001316019 (OMIM: 116600,176946) ephrin type-A r ( 922) 1088 114.2 3.3e-24 XP_016856024 (OMIM: 116600,176946) PREDICTED: ephr ( 965) 1088 114.2 3.4e-24 XP_016856023 (OMIM: 116600,176946) PREDICTED: ephr ( 973) 1088 114.2 3.5e-24 NP_004422 (OMIM: 116600,176946) ephrin type-A rece ( 976) 1088 114.2 3.5e-24 NP_001291466 (OMIM: 602188) ephrin type-A receptor ( 935) 1065 112.1 1.4e-23 NP_004429 (OMIM: 602188) ephrin type-A receptor 4 ( 986) 1065 112.2 1.5e-23 NP_001291465 (OMIM: 602188) ephrin type-A receptor ( 986) 1065 112.2 1.5e-23 XP_016861699 (OMIM: 600066) PREDICTED: ephrin type (1104) 987 105.2 2.1e-21 XP_005248726 (OMIM: 602190) PREDICTED: ephrin type ( 994) 961 102.7 1e-20 XP_016863367 (OMIM: 600004) PREDICTED: ephrin type ( 904) 929 99.8 7.1e-20 XP_016863369 (OMIM: 600004) PREDICTED: ephrin type ( 852) 926 99.5 8.2e-20 XP_016863368 (OMIM: 600004) PREDICTED: ephrin type ( 869) 925 99.4 8.9e-20 XP_016863370 (OMIM: 600004) PREDICTED: ephrin type ( 817) 922 99.1 1e-19 NP_004430 (OMIM: 600004) ephrin type-A receptor 5 (1037) 898 97.1 5.4e-19 NP_001305690 (OMIM: 600004) ephrin type-A receptor ( 969) 893 96.6 7.1e-19 NP_001268696 (OMIM: 600004) ephrin type-A receptor (1004) 893 96.6 7.3e-19 NP_001268694 (OMIM: 600004) ephrin type-A receptor (1038) 893 96.6 7.5e-19 XP_006710504 (OMIM: 600997,603688) PREDICTED: ephr ( 980) 887 96.0 1e-18 NP_004433 (OMIM: 600997,603688) ephrin type-B rece ( 987) 887 96.0 1e-18 NP_059145 (OMIM: 600997,603688) ephrin type-B rece ( 986) 882 95.6 1.4e-18 NP_001296122 (OMIM: 600997,603688) ephrin type-B r (1055) 877 95.2 2.1e-18 NP_005223 (OMIM: 179610) ephrin type-A receptor 1 ( 976) 837 91.5 2.4e-17 >>XP_011514182 (OMIM: 602757) PREDICTED: ephrin type-B r (1022 aa) initn: 5869 init1: 5869 opt: 6985 Z-score: 3439.5 bits: 648.0 E(85289): 7.7e-185 Smith-Waterman score: 6985; 99.8% identity (99.9% similar) in 1022 aa overlap (1-1021:1-1022) 10 20 30 40 50 60 pF1KB0 MATEGAAQLGNRVAGMVCSLWVLLLVSSVLALEEVLLDTTGETSEIGWLTYPPGGWDEVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MATEGAAQLGNRVAGMVCSLWVLLLVSSVLALEEVLLDTTGETSEIGWLTYPPGGWDEVS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 VLDDQRRLTRTFEACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLDDQRRLTRTFEACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVS 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 GGTCRETFTLYYRQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSS-AAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: XP_011 GGTCRETFTLYYRQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSSAAW 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB0 AVGPHGAGQRAGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVGPHGAGQRAGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB0 ASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGC 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB0 RCQPGYQPARGDKACQACPRGLYKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASS ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: XP_011 RCQPGYQPARGDKACQACPRGLYKASAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASS 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB0 DPPEAPCTGPPSAPQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPPEAPCTGPPSAPQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASG 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB0 GGGTCHRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGGTCHRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAI 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB0 NVSTSHEVPSAVPVVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVSTSHEVPSAVPVVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLT 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB0 SETNTATVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SETNTATVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGS 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB0 ILGALAFLLLAAITVLAVVFQRKRRGTGYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILGALAFLLLAAITVLAVVFQRKRRGTGYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIR 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB0 ELAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGR 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB0 AAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGV 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB0 AAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLGHSPQGPSCLLRWAAPEVIAHGKHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLGHSPQGPSCLLRWAAPEVIAHGKHT 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB0 TSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQ 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB0 KDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSA 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KB0 IGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQGSV 970 980 990 1000 1010 1020 1020 pF1KB0 EV :: XP_011 EV >>NP_004436 (OMIM: 602757) ephrin type-B receptor 6 isof (1022 aa) initn: 5869 init1: 5869 opt: 6985 Z-score: 3439.5 bits: 648.0 E(85289): 7.7e-185 Smith-Waterman score: 6985; 99.8% identity (99.9% similar) in 1022 aa overlap (1-1021:1-1022) 10 20 30 40 50 60 pF1KB0 MATEGAAQLGNRVAGMVCSLWVLLLVSSVLALEEVLLDTTGETSEIGWLTYPPGGWDEVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MATEGAAQLGNRVAGMVCSLWVLLLVSSVLALEEVLLDTTGETSEIGWLTYPPGGWDEVS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 VLDDQRRLTRTFEACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VLDDQRRLTRTFEACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVS 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 GGTCRETFTLYYRQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSS-AAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: NP_004 GGTCRETFTLYYRQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSSAAW 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB0 AVGPHGAGQRAGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AVGPHGAGQRAGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB0 ASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGC 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB0 RCQPGYQPARGDKACQACPRGLYKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASS ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: NP_004 RCQPGYQPARGDKACQACPRGLYKASAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASS 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB0 DPPEAPCTGPPSAPQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DPPEAPCTGPPSAPQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASG 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB0 GGGTCHRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GGGTCHRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAI 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB0 NVSTSHEVPSAVPVVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NVSTSHEVPSAVPVVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLT 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB0 SETNTATVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SETNTATVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGS 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB0 ILGALAFLLLAAITVLAVVFQRKRRGTGYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ILGALAFLLLAAITVLAVVFQRKRRGTGYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIR 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB0 ELAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ELAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGR 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB0 AAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGV 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB0 AAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLGHSPQGPSCLLRWAAPEVIAHGKHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLGHSPQGPSCLLRWAAPEVIAHGKHT 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB0 TSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQ 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB0 KDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSA 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KB0 IGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQGSV 970 980 990 1000 1010 1020 1020 pF1KB0 EV :: NP_004 EV >>XP_006715944 (OMIM: 602757) PREDICTED: ephrin type-B r (1022 aa) initn: 5869 init1: 5869 opt: 6985 Z-score: 3439.5 bits: 648.0 E(85289): 7.7e-185 Smith-Waterman score: 6985; 99.8% identity (99.9% similar) in 1022 aa overlap (1-1021:1-1022) 10 20 30 40 50 60 pF1KB0 MATEGAAQLGNRVAGMVCSLWVLLLVSSVLALEEVLLDTTGETSEIGWLTYPPGGWDEVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MATEGAAQLGNRVAGMVCSLWVLLLVSSVLALEEVLLDTTGETSEIGWLTYPPGGWDEVS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 VLDDQRRLTRTFEACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VLDDQRRLTRTFEACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVS 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 GGTCRETFTLYYRQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSS-AAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: XP_006 GGTCRETFTLYYRQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSSAAW 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB0 AVGPHGAGQRAGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AVGPHGAGQRAGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB0 ASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGC 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB0 RCQPGYQPARGDKACQACPRGLYKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASS ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: XP_006 RCQPGYQPARGDKACQACPRGLYKASAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASS 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB0 DPPEAPCTGPPSAPQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DPPEAPCTGPPSAPQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASG 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB0 GGGTCHRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GGGTCHRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAI 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB0 NVSTSHEVPSAVPVVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NVSTSHEVPSAVPVVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLT 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB0 SETNTATVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SETNTATVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGS 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB0 ILGALAFLLLAAITVLAVVFQRKRRGTGYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ILGALAFLLLAAITVLAVVFQRKRRGTGYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIR 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB0 ELAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ELAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGR 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB0 AAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGV 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB0 AAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLGHSPQGPSCLLRWAAPEVIAHGKHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLGHSPQGPSCLLRWAAPEVIAHGKHT 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB0 TSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQ 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB0 KDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSA 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KB0 IGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQGSV 970 980 990 1000 1010 1020 1020 pF1KB0 EV :: XP_006 EV >>XP_011514181 (OMIM: 602757) PREDICTED: ephrin type-B r (1022 aa) initn: 5869 init1: 5869 opt: 6985 Z-score: 3439.5 bits: 648.0 E(85289): 7.7e-185 Smith-Waterman score: 6985; 99.8% identity (99.9% similar) in 1022 aa overlap (1-1021:1-1022) 10 20 30 40 50 60 pF1KB0 MATEGAAQLGNRVAGMVCSLWVLLLVSSVLALEEVLLDTTGETSEIGWLTYPPGGWDEVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MATEGAAQLGNRVAGMVCSLWVLLLVSSVLALEEVLLDTTGETSEIGWLTYPPGGWDEVS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 VLDDQRRLTRTFEACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLDDQRRLTRTFEACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVS 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 GGTCRETFTLYYRQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSS-AAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: XP_011 GGTCRETFTLYYRQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSSAAW 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB0 AVGPHGAGQRAGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVGPHGAGQRAGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB0 ASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGC 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB0 RCQPGYQPARGDKACQACPRGLYKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASS ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: XP_011 RCQPGYQPARGDKACQACPRGLYKASAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASS 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB0 DPPEAPCTGPPSAPQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPPEAPCTGPPSAPQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASG 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB0 GGGTCHRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGGTCHRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAI 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB0 NVSTSHEVPSAVPVVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVSTSHEVPSAVPVVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLT 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB0 SETNTATVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SETNTATVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGS 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB0 ILGALAFLLLAAITVLAVVFQRKRRGTGYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILGALAFLLLAAITVLAVVFQRKRRGTGYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIR 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB0 ELAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGR 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB0 AAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGV 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB0 AAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLGHSPQGPSCLLRWAAPEVIAHGKHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLGHSPQGPSCLLRWAAPEVIAHGKHT 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB0 TSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQ 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB0 KDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSA 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KB0 IGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQGSV 970 980 990 1000 1010 1020 1020 pF1KB0 EV :: XP_011 EV >>XP_011514183 (OMIM: 602757) PREDICTED: ephrin type-B r (1021 aa) initn: 4069 init1: 4069 opt: 6966 Z-score: 3430.2 bits: 646.3 E(85289): 2.5e-184 Smith-Waterman score: 6966; 99.7% identity (99.8% similar) in 1022 aa overlap (1-1021:1-1021) 10 20 30 40 50 60 pF1KB0 MATEGAAQLGNRVAGMVCSLWVLLLVSSVLALEEVLLDTTGETSEIGWLTYPPGGWDEVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MATEGAAQLGNRVAGMVCSLWVLLLVSSVLALEEVLLDTTGETSEIGWLTYPPGGWDEVS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 VLDDQRRLTRTFEACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLDDQRRLTRTFEACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVS 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 GGTCRETFTLYYRQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSS-AAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: XP_011 GGTCRETFTLYYRQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSSAAW 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB0 AVGPHGAGQRAGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVGPHGAGQRAGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB0 ASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGC 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB0 RCQPGYQPARGDKACQACPRGLYKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASS ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: XP_011 RCQPGYQPARGDKACQACPRGLYKASAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASS 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB0 DPPEAPCTGPPSAPQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPPEAPCTGPPSAPQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASG 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB0 GGGTCHRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGGTCHRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAI 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB0 NVSTSHEVPSAVPVVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVSTSHEVPSAVPVVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLT 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB0 SETNTATVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SETNTATVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGS 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB0 ILGALAFLLLAAITVLAVVFQRKRRGTGYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILGALAFLLLAAITVLAVVFQRKRRGTGYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIR 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB0 ELAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGR 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB0 AAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGV :::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::: XP_011 AAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLR-REGQFSSLQLVAMQRGV 730 740 750 760 770 780 790 800 810 820 830 pF1KB0 AAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLGHSPQGPSCLLRWAAPEVIAHGKHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLGHSPQGPSCLLRWAAPEVIAHGKHT 780 790 800 810 820 830 840 850 860 870 880 890 pF1KB0 TSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQ 840 850 860 870 880 890 900 910 920 930 940 950 pF1KB0 KDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSA 900 910 920 930 940 950 960 970 980 990 1000 1010 pF1KB0 IGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQGSV 960 970 980 990 1000 1010 1020 pF1KB0 EV :: XP_011 EV 1020 >>NP_001267724 (OMIM: 602757) ephrin type-B receptor 6 i (729 aa) initn: 5012 init1: 5012 opt: 5012 Z-score: 2476.2 bits: 469.3 E(85289): 3.5e-131 Smith-Waterman score: 5012; 99.9% identity (100.0% similar) in 729 aa overlap (293-1021:1-729) 270 280 290 300 310 320 pF1KB0 VAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGCRCQPGYQPARGDKACQACPRGLY :::::::::::::::::::::::::::::: NP_001 MVAVGGCRCQPGYQPARGDKACQACPRGLY 10 20 30 330 340 350 360 370 380 pF1KB0 KSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEAPCTGPPSAPQELWFEVQG :.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KASAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEAPCTGPPSAPQELWFEVQG 40 50 60 70 80 90 390 400 410 420 430 440 pF1KB0 SALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCHRCRDEVHFDPRQRGLTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCHRCRDEVHFDPRQRGLTE 100 110 120 130 140 150 450 460 470 480 490 500 pF1KB0 SRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPSAVPVVHQVSRASN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPSAVPVVHQVSRASN 160 170 180 190 200 210 510 520 530 540 550 560 pF1KB0 SITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLTSETNTATVTQLSPGHIYGFQVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLTSETNTATVTQLSPGHIYGFQVRA 220 230 240 250 260 270 570 580 590 600 610 620 pF1KB0 RTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGSILGALAFLLLAAITVLAVVFQRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGSILGALAFLLLAAITVLAVVFQRK 280 290 300 310 320 330 630 640 650 660 670 680 pF1KB0 RRGTGYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIRELAREVDPAYIKIEEVIGTGSFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRGTGYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIRELAREVDPAYIKIEEVIGTGSFG 340 350 360 370 380 390 690 700 710 720 730 740 pF1KB0 EVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGRAAVLGQFQHPNILRLEGVVTKSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGRAAVLGQFQHPNILRLEGVVTKSR 400 410 420 430 440 450 750 760 770 780 790 800 pF1KB0 PLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRSLSAHSVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRSLSAHSVL 460 470 480 490 500 510 810 820 830 840 850 860 pF1KB0 VNSHLVCKVARLGHSPQGPSCLLRWAAPEVIAHGKHTTSSDVWSFGILMWEVMSYGERPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNSHLVCKVARLGHSPQGPSCLLRWAAPEVIAHGKHTTSSDVWSFGILMWEVMSYGERPY 520 530 540 550 560 570 870 880 890 900 910 920 pF1KB0 WDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKP 580 590 600 610 620 630 930 940 950 960 970 980 pF1KB0 DTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSAIGLECYQDNFSKFGLCTFSDVAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSAIGLECYQDNFSKFGLCTFSDVAQ 640 650 660 670 680 690 990 1000 1010 1020 pF1KB0 LSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQGSVEV ::::::::::::::::::::::::::::::::::::::: NP_001 LSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQGSVEV 700 710 720 >>NP_001267723 (OMIM: 602757) ephrin type-B receptor 6 i (729 aa) initn: 5012 init1: 5012 opt: 5012 Z-score: 2476.2 bits: 469.3 E(85289): 3.5e-131 Smith-Waterman score: 5012; 99.9% identity (100.0% similar) in 729 aa overlap (293-1021:1-729) 270 280 290 300 310 320 pF1KB0 VAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGCRCQPGYQPARGDKACQACPRGLY :::::::::::::::::::::::::::::: NP_001 MVAVGGCRCQPGYQPARGDKACQACPRGLY 10 20 30 330 340 350 360 370 380 pF1KB0 KSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEAPCTGPPSAPQELWFEVQG :.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KASAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEAPCTGPPSAPQELWFEVQG 40 50 60 70 80 90 390 400 410 420 430 440 pF1KB0 SALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCHRCRDEVHFDPRQRGLTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCHRCRDEVHFDPRQRGLTE 100 110 120 130 140 150 450 460 470 480 490 500 pF1KB0 SRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPSAVPVVHQVSRASN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPSAVPVVHQVSRASN 160 170 180 190 200 210 510 520 530 540 550 560 pF1KB0 SITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLTSETNTATVTQLSPGHIYGFQVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLTSETNTATVTQLSPGHIYGFQVRA 220 230 240 250 260 270 570 580 590 600 610 620 pF1KB0 RTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGSILGALAFLLLAAITVLAVVFQRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGSILGALAFLLLAAITVLAVVFQRK 280 290 300 310 320 330 630 640 650 660 670 680 pF1KB0 RRGTGYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIRELAREVDPAYIKIEEVIGTGSFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRGTGYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIRELAREVDPAYIKIEEVIGTGSFG 340 350 360 370 380 390 690 700 710 720 730 740 pF1KB0 EVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGRAAVLGQFQHPNILRLEGVVTKSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGRAAVLGQFQHPNILRLEGVVTKSR 400 410 420 430 440 450 750 760 770 780 790 800 pF1KB0 PLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRSLSAHSVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRSLSAHSVL 460 470 480 490 500 510 810 820 830 840 850 860 pF1KB0 VNSHLVCKVARLGHSPQGPSCLLRWAAPEVIAHGKHTTSSDVWSFGILMWEVMSYGERPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNSHLVCKVARLGHSPQGPSCLLRWAAPEVIAHGKHTTSSDVWSFGILMWEVMSYGERPY 520 530 540 550 560 570 870 880 890 900 910 920 pF1KB0 WDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKP 580 590 600 610 620 630 930 940 950 960 970 980 pF1KB0 DTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSAIGLECYQDNFSKFGLCTFSDVAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSAIGLECYQDNFSKFGLCTFSDVAQ 640 650 660 670 680 690 990 1000 1010 1020 pF1KB0 LSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQGSVEV ::::::::::::::::::::::::::::::::::::::: NP_001 LSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQGSVEV 700 710 720 >>XP_011514184 (OMIM: 602757) PREDICTED: ephrin type-B r (991 aa) initn: 4407 init1: 3118 opt: 3149 Z-score: 1563.3 bits: 300.8 E(85289): 2.5e-80 Smith-Waterman score: 6716; 96.8% identity (96.9% similar) in 1022 aa overlap (1-1021:1-991) 10 20 30 40 50 60 pF1KB0 MATEGAAQLGNRVAGMVCSLWVLLLVSSVLALEEVLLDTTGETSEIGWLTYPPGGWDEVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MATEGAAQLGNRVAGMVCSLWVLLLVSSVLALEEVLLDTTGETSEIGWLTYPPGGWDEVS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 VLDDQRRLTRTFEACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLDDQRRLTRTFEACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVS 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 GGTCRETFTLYYRQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSS-AAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: XP_011 GGTCRETFTLYYRQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSSAAW 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB0 AVGPHGAGQRAGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVGPHGAGQRAGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB0 ASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGC 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB0 RCQPGYQPARGDKACQACPRGLYKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASS ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: XP_011 RCQPGYQPARGDKACQACPRGLYKASAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASS 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB0 DPPEAPCTGPPSAPQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPPEAPCTGPPSAPQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASG 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB0 GGGTCHRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGGTCHRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAI 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB0 NVSTSHEVPSAVPVVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLT ::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVSTSHEVPSAVPVVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQ----------- 490 500 510 520 540 550 560 570 580 590 pF1KB0 SETNTATVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGS :::::::::::::::::::::::::::::::::::::::: XP_011 --------------------VRARTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGS 530 540 550 560 600 610 620 630 640 650 pF1KB0 ILGALAFLLLAAITVLAVVFQRKRRGTGYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILGALAFLLLAAITVLAVVFQRKRRGTGYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIR 570 580 590 600 610 620 660 670 680 690 700 710 pF1KB0 ELAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGR 630 640 650 660 670 680 720 730 740 750 760 770 pF1KB0 AAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGV 690 700 710 720 730 740 780 790 800 810 820 830 pF1KB0 AAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLGHSPQGPSCLLRWAAPEVIAHGKHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLGHSPQGPSCLLRWAAPEVIAHGKHT 750 760 770 780 790 800 840 850 860 870 880 890 pF1KB0 TSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQ 810 820 830 840 850 860 900 910 920 930 940 950 pF1KB0 KDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSA 870 880 890 900 910 920 960 970 980 990 1000 1010 pF1KB0 IGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQGSV 930 940 950 960 970 980 1020 pF1KB0 EV :: XP_011 EV 990 >>NP_004432 (OMIM: 600600) ephrin type-B receptor 1 prec (984 aa) initn: 2546 init1: 729 opt: 1894 Z-score: 949.4 bits: 187.2 E(85289): 3.8e-46 Smith-Waterman score: 3193; 48.0% identity (73.8% similar) in 1017 aa overlap (20-1015:6-978) 10 20 30 40 50 60 pF1KB0 MATEGAAQLGNRVAGMVCSLWVLLLVSSVLALEEVLLDTTGETSEIGWLTYPPGGWDEVS : .:::.:.: :.::.:.:: :.:.:: . : .::.::: NP_004 MALDYLLLLLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVS 10 20 30 40 70 80 90 100 110 120 pF1KB0 VLDDQRRLTRTFEACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVS :.. ::...:.: : .:.::: : :..::::.: . ...:.:: :::: NP_004 GYDENLNTIRTYQVCNVF-EP---NQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNV 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB0 GGTCRETFTLYYRQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSAAWA :.:.:::.::: ... . . . : . ::::::::::: :.. . NP_004 PGSCKETFNLYYYETDSVIATKKSAFWSEAPYLKVDTIAADESF----------SQVDF- 110 120 130 140 150 190 200 210 220 230 240 pF1KB0 VGPHGAGQRAGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSFA : : ...:.. :::::::. :::.:::: :::..:..::.: ::.....:: NP_004 ------GGRL-MKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKKCPSIVQNFA 160 170 180 190 200 250 260 270 280 290 300 pF1KB0 SFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGCR ::::. .:: ..::: : :::. .:: : : : .:.:::.:.::: .: : NP_004 VFPETM-TGAESTSLVIARGTCIPNAE-EVD--------VPIKLYCNGDGEWMVPIGRCT 210 220 230 240 250 310 320 330 340 350 360 pF1KB0 CQPGYQPARGDKACQACPRGLYKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASSD :.:::.: ... ::.::: : .:.: :: ::. :..: :.:.: : :.:::. : NP_004 CKPGYEP-ENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCRTGYYRADFD 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB0 PPEAPCTGPPSAPQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGG :::. ::. ::.:... :. ....:.:. ::: ::: :. .:..::.:.. .. NP_004 PPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRR----- 320 330 340 350 360 430 440 450 460 470 480 pF1KB0 GGTCHRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAIN .: :: :.:.: ::: :::: :: ...: ::.:: ...::.:::: :: ::: ...: NP_004 --SCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVN 370 380 390 400 410 420 490 500 510 520 530 540 pF1KB0 VSTSHEVPSAVPVVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLTS ..:.. .::.::..:::: . :::.:::::.: :: ::::..:::.. ..: .: : NP_004 ITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARS 430 440 450 460 470 480 550 560 570 580 590 600 pF1KB0 ETNTATVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGSI .:::: . : :: .: ::::::.::.: ..::. :::: . . .:.: :.: :. :: NP_004 QTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSA 490 500 510 520 530 540 610 620 630 640 650 pF1KB0 LGALAFLLLAAITVLAVVFQRKR---RGTGYTEQLQQYS----SPGLGVKYYIDPSTYED ....:.. .......: .::: . . :...::.:: :::. : :::: :::: NP_004 AAGVVFVV--SLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGM--KIYIDPFTYED 550 560 570 580 590 600 660 670 680 690 700 710 pF1KB0 PCQAIRELAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQ : .:.::.:.:.: ...:::::::.: :::: .:::. :.:: :::..: :: .:. . NP_004 PNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQR 610 620 630 640 650 660 720 730 740 750 760 770 pF1KB0 MTFLGRAAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLV ::..:...:::.::::.:::::::::::.:..::::: : ::::::: .:::. .::: NP_004 RDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLV 670 680 690 700 710 720 780 790 800 810 820 pF1KB0 AMQRGVAAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLGHS---------PQGPSCL .: ::.::.:.::. . .:::.:.:...::::.:::::. .: : : : : NP_004 GMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSL 730 740 750 760 770 780 830 840 850 860 870 pF1KB0 -----LRWAAPEVIAHGKHTTSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFR .::.:::.::. : :..:::::.::.::::::.:::::::::.:.:.:::::..: NP_004 GGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYR 790 800 810 820 830 840 880 890 900 910 920 930 pF1KB0 LPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQAL :::: :: .:: :::: ::::: ::.: ..: ..:::::.: .:.. . ::: : NP_004 LPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPL 850 860 870 880 890 900 940 950 960 970 980 990 pF1KB0 LTPVALDFPCLDSPQAWLSAIGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQ : :: . . . ::::: . :.:.: :. ... :.:.. ::: .:::::::: NP_004 LDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAGHQ 910 920 930 940 950 960 1000 1010 1020 pF1KB0 KKLLHHIQLLQQHLRQQGSVEV ::.:. :. .. .. : NP_004 KKILNSIHSMRVQISQSPTAMA 970 980 >>NP_004434 (OMIM: 601839) ephrin type-B receptor 3 prec (998 aa) initn: 2560 init1: 813 opt: 1806 Z-score: 906.3 bits: 179.2 E(85289): 9.7e-44 Smith-Waterman score: 3024; 47.0% identity (71.9% similar) in 1020 aa overlap (20-1021:26-998) 10 20 30 40 50 pF1KB0 MATEGAAQLGNRVAGMVCSLWVLLLVSSVLALEEVLLDTTGETSEIGWLTYPPG : .::: .. ::::.:.:: :::..: ..: . NP_004 MARARPPPPPSPPPGLLPLLPPLLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPES 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB0 GWDEVSVLDDQRRLTRTFEACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRAC ::.::: :. ::...:.: ..:.:::.: :. :: .::....:.:.:: : NP_004 GWEEVSGYDEAMNPIRTYQVCNVRE----SSQNNWLRTGFIWRRDVQRVYVELKFTVRDC 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 SSLGVSGGTCRETFTLYYRQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSS .:. :.:.:::.:.: .:. . : : . ..:::::: :::: . NP_004 NSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLD------ 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB0 SSAAWAVGPHGAGQRAGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPA :: ..:.: ::::::.. :::.:::: :::..:..:: : : . NP_004 ---------------AG-RVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFYKKCAS 180 190 200 210 240 250 260 270 280 290 pF1KB0 VLRSFASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMV . .:: :::: .:: .::: : :::. .: : .: : .:.:::.:.::: NP_004 TTAGFALFPETL-TGAEPTSLVIAPGTCIPNAV--EVSV-------PLKLYCNGDGEWMV 220 230 240 250 260 300 310 320 330 340 350 pF1KB0 AVGGCRCQPGYQPARGDKACQACPRGLYKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGF ::.: : :..:: .. :. :: : ::.. :..:: ::: :.. .::: .: : ..: NP_004 PVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNF 270 280 290 300 310 320 360 370 380 390 400 410 pF1KB0 YRASSDPPEAPCTGPPSAPQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQ :::.:: .. :: :: :. . .:. ..:.:.: ::.:::: :::.::.::.:.: NP_004 YRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCHG-- 330 340 350 360 370 380 420 430 440 450 460 470 pF1KB0 EPASGGGGTCHRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPP .::...: :: :.:.: ::: :::: :: .. : ::. : .::::::::: :: :: NP_004 ---AGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPP 390 400 410 420 430 480 490 500 510 520 530 pF1KB0 QAAAINVSTSHEVPSAVPVVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESH . ::.:..:.. .:: ::... : ...:.:.:: :.. :: ::::...:....: . NP_004 RYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEGIAS 440 450 460 470 480 490 540 550 560 570 580 590 pF1KB0 SFTLTSETNTATVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQ-GELSSQLPERL :.::. :.. . : : : ::::::.::.: :. . :.: . : ..:: :.: NP_004 --TVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQL 500 510 520 530 540 550 600 610 620 630 640 650 pF1KB0 SLVIGSILGALAFLLLAAITVLAVVFQRKRR-GTG--YTEQLQQYSSPGLGVKYYIDPST :..:: ..:.:.. :..:.:.: ::.: :. :::.:::: .::. : :::: : NP_004 PLIVGSATAGLVFVV--AVVVIAIVCLRKQRHGSDSEYTEKLQQYIAPGM--KVYIDPFT 560 570 580 590 600 610 660 670 680 690 700 710 pF1KB0 YEDPCQAIRELAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAGGAE :::: .:.::.:.:.: . .:::::::.: :::: .:::. :::: :::..: .: .: NP_004 YEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTE 620 630 640 650 660 670 720 730 740 750 760 770 pF1KB0 SLQMTFLGRAAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSL . ::..:...:::.::::.:::::::::::.:.:::::: :::::: .:::. . NP_004 RQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVI 680 690 700 710 720 730 780 790 800 810 820 pF1KB0 QLVAMQRGVAAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLGHS------PQGP--- :::.: ::.::.:.::: . .:::.:.:...::::.:::::. .: : :. : NP_004 QLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYT 740 750 760 770 780 790 830 840 850 860 870 pF1KB0 SCL-----LRWAAPEVIAHGKHTTSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQ : : .::.:::.::. : :..:::::.::.::::::::::::::::.:.:.::.:: NP_004 SSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQ 800 810 820 830 840 850 880 890 900 910 920 930 pF1KB0 EFRLPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPS ..::::: :: .:: :::: : .:: ::.:.:.: ..::.::. .:.. .. : NP_004 DYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMS 860 870 880 890 900 910 940 950 960 970 980 990 pF1KB0 QALLTPVALDFPCLDSPQAWLSAIGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLA : :: .. :. . . ::.:: . :...: . :. .:. :::.. ::: .:.::: NP_004 QPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLA 920 930 940 950 960 970 1000 1010 1020 pF1KB0 GHQKKLLHHIQLLQQHLRQQGSVEV :::::.: :: .. .. : :.: NP_004 GHQKKILSSIQDMRLQMNQTLPVQV 980 990 1021 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 11:39:13 2016 done: Thu Nov 3 11:39:16 2016 Total Scan time: 16.980 Total Display time: 0.320 Function used was FASTA [36.3.4 Apr, 2011]