FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0150, 1464 aa 1>>>pF1KB0150 1464 - 1464 aa - 1464 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.7382+/-0.00049; mu= -12.2649+/- 0.030 mean_var=367.9923+/-78.720, 0's: 0 Z-trim(118.8): 101 B-trim: 1595 in 1/53 Lambda= 0.066858 statistics sampled from 32082 (32187) to 32082 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.692), E-opt: 0.2 (0.377), width: 16 Scan time: 16.230 The best scores are: opt bits E(85289) NP_001308636 (OMIM: 601993) nuclear receptor coact (1464) 9845 965.1 0 NP_001308632 (OMIM: 601993) nuclear receptor coact (1464) 9845 965.1 0 NP_006531 (OMIM: 601993) nuclear receptor coactiva (1464) 9845 965.1 0 NP_001308642 (OMIM: 601993) nuclear receptor coact (1310) 8843 868.4 0 XP_016868452 (OMIM: 601993) PREDICTED: nuclear rec (1533) 8824 866.6 0 XP_016868454 (OMIM: 601993) PREDICTED: nuclear rec (1533) 8824 866.6 0 XP_016868453 (OMIM: 601993) PREDICTED: nuclear rec (1533) 8824 866.6 0 XP_016868456 (OMIM: 601993) PREDICTED: nuclear rec (1533) 8824 866.6 0 XP_016868455 (OMIM: 601993) PREDICTED: nuclear rec (1533) 8824 866.6 0 XP_016868460 (OMIM: 601993) PREDICTED: nuclear rec (1533) 8824 866.6 0 XP_016868459 (OMIM: 601993) PREDICTED: nuclear rec (1533) 8824 866.6 0 XP_016868458 (OMIM: 601993) PREDICTED: nuclear rec (1533) 8824 866.6 0 XP_016868451 (OMIM: 601993) PREDICTED: nuclear rec (1533) 8824 866.6 0 XP_016868450 (OMIM: 601993) PREDICTED: nuclear rec (1533) 8824 866.6 0 XP_016868457 (OMIM: 601993) PREDICTED: nuclear rec (1533) 8824 866.6 0 XP_016868461 (OMIM: 601993) PREDICTED: nuclear rec (1379) 7822 770.0 0 NP_001308640 (OMIM: 601993) nuclear receptor coact (1395) 5802 575.1 1.3e-162 NP_001308641 (OMIM: 601993) nuclear receptor coact (1395) 5802 575.1 1.3e-162 XP_016868462 (OMIM: 601993) PREDICTED: nuclear rec ( 799) 5304 527.0 2.3e-148 NP_001167559 (OMIM: 601937) nuclear receptor coact (1415) 2566 263.0 1.2e-68 NP_001167558 (OMIM: 601937) nuclear receptor coact (1423) 2531 259.6 1.2e-67 NP_006525 (OMIM: 601937) nuclear receptor coactiva (1420) 2524 258.9 2e-67 NP_858045 (OMIM: 601937) nuclear receptor coactiva (1424) 2517 258.3 3.2e-67 XP_016860657 (OMIM: 602691) PREDICTED: nuclear rec (1399) 1996 208.0 4.2e-52 XP_016860658 (OMIM: 602691) PREDICTED: nuclear rec (1399) 1996 208.0 4.2e-52 XP_005264685 (OMIM: 602691) PREDICTED: nuclear rec (1399) 1996 208.0 4.2e-52 NP_671756 (OMIM: 602691) nuclear receptor coactiva (1399) 1996 208.0 4.2e-52 XP_005264683 (OMIM: 602691) PREDICTED: nuclear rec (1440) 1996 208.0 4.3e-52 NP_671766 (OMIM: 602691) nuclear receptor coactiva (1440) 1996 208.0 4.3e-52 XP_005264682 (OMIM: 602691) PREDICTED: nuclear rec (1441) 1996 208.0 4.3e-52 NP_003734 (OMIM: 602691) nuclear receptor coactiva (1441) 1996 208.0 4.3e-52 >>NP_001308636 (OMIM: 601993) nuclear receptor coactivat (1464 aa) initn: 9845 init1: 9845 opt: 9845 Z-score: 5147.7 bits: 965.1 E(85289): 0 Smith-Waterman score: 9845; 99.9% identity (100.0% similar) in 1464 aa overlap (1-1464:1-1464) 10 20 30 40 50 60 pF1KB0 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 SNINFPINGPKEQMGMPIGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: NP_001 SNINFPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGISQQPDPGFTGATT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGISQQPDPGFTGATT 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 PQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQSPPHFGQQAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQSPPHFGQQAN 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 TSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQVNDPALRGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQVNDPALRGG 1390 1400 1410 1420 1430 1440 1450 1460 pF1KB0 NLFPNQLPGMDMIKQEGDTTRKYC :::::::::::::::::::::::: NP_001 NLFPNQLPGMDMIKQEGDTTRKYC 1450 1460 >>NP_001308632 (OMIM: 601993) nuclear receptor coactivat (1464 aa) initn: 9845 init1: 9845 opt: 9845 Z-score: 5147.7 bits: 965.1 E(85289): 0 Smith-Waterman score: 9845; 99.9% identity (100.0% similar) in 1464 aa overlap (1-1464:1-1464) 10 20 30 40 50 60 pF1KB0 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 SNINFPINGPKEQMGMPIGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: NP_001 SNINFPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGISQQPDPGFTGATT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGISQQPDPGFTGATT 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 PQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQSPPHFGQQAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQSPPHFGQQAN 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 TSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQVNDPALRGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQVNDPALRGG 1390 1400 1410 1420 1430 1440 1450 1460 pF1KB0 NLFPNQLPGMDMIKQEGDTTRKYC :::::::::::::::::::::::: NP_001 NLFPNQLPGMDMIKQEGDTTRKYC 1450 1460 >>NP_006531 (OMIM: 601993) nuclear receptor coactivator (1464 aa) initn: 9845 init1: 9845 opt: 9845 Z-score: 5147.7 bits: 965.1 E(85289): 0 Smith-Waterman score: 9845; 99.9% identity (100.0% similar) in 1464 aa overlap (1-1464:1-1464) 10 20 30 40 50 60 pF1KB0 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 SNINFPINGPKEQMGMPIGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: NP_006 SNINFPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB0 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGISQQPDPGFTGATT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGISQQPDPGFTGATT 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB0 PQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQSPPHFGQQAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQSPPHFGQQAN 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB0 TSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQVNDPALRGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQVNDPALRGG 1390 1400 1410 1420 1430 1440 1450 1460 pF1KB0 NLFPNQLPGMDMIKQEGDTTRKYC :::::::::::::::::::::::: NP_006 NLFPNQLPGMDMIKQEGDTTRKYC 1450 1460 >>NP_001308642 (OMIM: 601993) nuclear receptor coactivat (1310 aa) initn: 8843 init1: 8843 opt: 8843 Z-score: 4626.1 bits: 868.4 E(85289): 0 Smith-Waterman score: 8843; 99.9% identity (100.0% similar) in 1310 aa overlap (155-1464:1-1310) 130 140 150 160 170 180 pF1KB0 GFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSIVNGG :::::::::::::::::::::::::::::: NP_001 MNKSVYSILHVGDHTEFVKNLLPKSIVNGG 10 20 30 190 200 210 220 230 240 pF1KB0 SWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKEEGED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKEEGED 40 50 60 70 80 90 250 260 270 280 290 300 pF1KB0 LQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLVRRCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLVRRCI 100 110 120 130 140 150 310 320 330 340 350 360 pF1KB0 QKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQTTNEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQTTNEP 160 170 180 190 200 210 370 380 390 400 410 420 pF1KB0 QLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLSSNIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLSSNIN 220 230 240 250 260 270 430 440 450 460 470 480 pF1KB0 FPINGPKEQMGMPIGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPGQPTS :::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::: NP_001 FPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPGQPTS 280 290 300 310 320 330 490 500 510 520 530 540 pF1KB0 MLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQALSEGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQALSEGH 340 350 360 370 380 390 550 560 570 580 590 600 pF1KB0 GVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQAESSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQAESSC 400 410 420 430 440 450 610 620 630 640 650 660 pF1KB0 HPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASSLSDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASSLSDT 460 470 480 490 500 510 670 680 690 700 710 720 pF1KB0 NKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESSSTAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESSSTAP 520 530 540 550 560 570 730 740 750 760 770 780 pF1KB0 GSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTKLIAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTKLIAM 580 590 600 610 620 630 790 800 810 820 830 840 pF1KB0 KTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAIINDLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAIINDLM 640 650 660 670 680 690 850 860 870 880 890 900 pF1KB0 QLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAGPFPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAGPFPP 700 710 720 730 740 750 910 920 930 940 950 960 pF1KB0 IRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSAVRVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSAVRVT 760 770 780 790 800 810 970 980 990 1000 1010 1020 pF1KB0 CAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGGPQYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGGPQYS 820 830 840 850 860 870 1030 1040 1050 1060 1070 1080 pF1KB0 QQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALLDQLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALLDQLY 880 890 900 910 920 930 1090 1100 1110 1120 1130 1140 pF1KB0 LALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQAQMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQAQMA 940 950 960 970 980 990 1150 1160 1170 1180 1190 1200 pF1KB0 QGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQQNRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQQNRQ 1000 1010 1020 1030 1040 1050 1210 1220 1230 1240 1250 1260 pF1KB0 PLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQRTLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQRTLM 1060 1070 1080 1090 1100 1110 1270 1280 1290 1300 1310 1320 pF1KB0 MRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGISQQPDPGFTGATTPQSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGISQQPDPGFTGATTPQSP 1120 1130 1140 1150 1160 1170 1330 1340 1350 1360 1370 1380 pF1KB0 LMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQSPPHFGQQANTSMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQSPPHFGQQANTSMY 1180 1190 1200 1210 1220 1230 1390 1400 1410 1420 1430 1440 pF1KB0 SNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQVNDPALRGGNLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQVNDPALRGGNLFP 1240 1250 1260 1270 1280 1290 1450 1460 pF1KB0 NQLPGMDMIKQEGDTTRKYC :::::::::::::::::::: NP_001 NQLPGMDMIKQEGDTTRKYC 1300 1310 >>XP_016868452 (OMIM: 601993) PREDICTED: nuclear recepto (1533 aa) initn: 8849 init1: 8801 opt: 8824 Z-score: 4615.2 bits: 866.6 E(85289): 0 Smith-Waterman score: 9430; 95.3% identity (95.4% similar) in 1496 aa overlap (1-1427:1-1496) 10 20 30 40 50 60 pF1KB0 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 SNINFPINGPKEQMGMPIGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: XP_016 SNINFPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 pF1KB0 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYG-------------- :::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGTGLRSPPPFTSPFS 1270 1280 1290 1300 1310 1320 1310 pF1KB0 -------------------------------------------------------ISQQP ::::: XP_016 PVSPSVGSQLLSHSSLHGSQMNLANQGMIGNLGGQLGPVRSPQVQHSTFQALSSGISQQP 1330 1340 1350 1360 1370 1380 1320 1330 1340 1350 1360 1370 pF1KB0 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS 1390 1400 1410 1420 1430 1440 1380 1390 1400 1410 1420 1430 pF1KB0 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ 1450 1460 1470 1480 1490 1500 1440 1450 1460 pF1KB0 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC XP_016 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC 1510 1520 1530 >>XP_016868454 (OMIM: 601993) PREDICTED: nuclear recepto (1533 aa) initn: 8849 init1: 8801 opt: 8824 Z-score: 4615.2 bits: 866.6 E(85289): 0 Smith-Waterman score: 9430; 95.3% identity (95.4% similar) in 1496 aa overlap (1-1427:1-1496) 10 20 30 40 50 60 pF1KB0 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 SNINFPINGPKEQMGMPIGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: XP_016 SNINFPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 pF1KB0 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYG-------------- :::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGTGLRSPPPFTSPFS 1270 1280 1290 1300 1310 1320 1310 pF1KB0 -------------------------------------------------------ISQQP ::::: XP_016 PVSPSVGSQLLSHSSLHGSQMNLANQGMIGNLGGQLGPVRSPQVQHSTFQALSSGISQQP 1330 1340 1350 1360 1370 1380 1320 1330 1340 1350 1360 1370 pF1KB0 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS 1390 1400 1410 1420 1430 1440 1380 1390 1400 1410 1420 1430 pF1KB0 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ 1450 1460 1470 1480 1490 1500 1440 1450 1460 pF1KB0 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC XP_016 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC 1510 1520 1530 >>XP_016868453 (OMIM: 601993) PREDICTED: nuclear recepto (1533 aa) initn: 8849 init1: 8801 opt: 8824 Z-score: 4615.2 bits: 866.6 E(85289): 0 Smith-Waterman score: 9430; 95.3% identity (95.4% similar) in 1496 aa overlap (1-1427:1-1496) 10 20 30 40 50 60 pF1KB0 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 SNINFPINGPKEQMGMPIGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: XP_016 SNINFPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 pF1KB0 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYG-------------- :::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGTGLRSPPPFTSPFS 1270 1280 1290 1300 1310 1320 1310 pF1KB0 -------------------------------------------------------ISQQP ::::: XP_016 PVSPSVGSQLLSHSSLHGSQMNLANQGMIGNLGGQLGPVRSPQVQHSTFQALSSGISQQP 1330 1340 1350 1360 1370 1380 1320 1330 1340 1350 1360 1370 pF1KB0 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS 1390 1400 1410 1420 1430 1440 1380 1390 1400 1410 1420 1430 pF1KB0 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ 1450 1460 1470 1480 1490 1500 1440 1450 1460 pF1KB0 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC XP_016 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC 1510 1520 1530 >>XP_016868456 (OMIM: 601993) PREDICTED: nuclear recepto (1533 aa) initn: 8849 init1: 8801 opt: 8824 Z-score: 4615.2 bits: 866.6 E(85289): 0 Smith-Waterman score: 9430; 95.3% identity (95.4% similar) in 1496 aa overlap (1-1427:1-1496) 10 20 30 40 50 60 pF1KB0 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 SNINFPINGPKEQMGMPIGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: XP_016 SNINFPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 pF1KB0 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYG-------------- :::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGTGLRSPPPFTSPFS 1270 1280 1290 1300 1310 1320 1310 pF1KB0 -------------------------------------------------------ISQQP ::::: XP_016 PVSPSVGSQLLSHSSLHGSQMNLANQGMIGNLGGQLGPVRSPQVQHSTFQALSSGISQQP 1330 1340 1350 1360 1370 1380 1320 1330 1340 1350 1360 1370 pF1KB0 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS 1390 1400 1410 1420 1430 1440 1380 1390 1400 1410 1420 1430 pF1KB0 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ 1450 1460 1470 1480 1490 1500 1440 1450 1460 pF1KB0 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC XP_016 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC 1510 1520 1530 >>XP_016868455 (OMIM: 601993) PREDICTED: nuclear recepto (1533 aa) initn: 8849 init1: 8801 opt: 8824 Z-score: 4615.2 bits: 866.6 E(85289): 0 Smith-Waterman score: 9430; 95.3% identity (95.4% similar) in 1496 aa overlap (1-1427:1-1496) 10 20 30 40 50 60 pF1KB0 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 SNINFPINGPKEQMGMPIGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: XP_016 SNINFPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 pF1KB0 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYG-------------- :::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGTGLRSPPPFTSPFS 1270 1280 1290 1300 1310 1320 1310 pF1KB0 -------------------------------------------------------ISQQP ::::: XP_016 PVSPSVGSQLLSHSSLHGSQMNLANQGMIGNLGGQLGPVRSPQVQHSTFQALSSGISQQP 1330 1340 1350 1360 1370 1380 1320 1330 1340 1350 1360 1370 pF1KB0 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS 1390 1400 1410 1420 1430 1440 1380 1390 1400 1410 1420 1430 pF1KB0 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ 1450 1460 1470 1480 1490 1500 1440 1450 1460 pF1KB0 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC XP_016 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC 1510 1520 1530 >>XP_016868460 (OMIM: 601993) PREDICTED: nuclear recepto (1533 aa) initn: 8849 init1: 8801 opt: 8824 Z-score: 4615.2 bits: 866.6 E(85289): 0 Smith-Waterman score: 9430; 95.3% identity (95.4% similar) in 1496 aa overlap (1-1427:1-1496) 10 20 30 40 50 60 pF1KB0 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 SNINFPINGPKEQMGMPIGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: XP_016 SNINFPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB0 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB0 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB0 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 pF1KB0 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYG-------------- :::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGTGLRSPPPFTSPFS 1270 1280 1290 1300 1310 1320 1310 pF1KB0 -------------------------------------------------------ISQQP ::::: XP_016 PVSPSVGSQLLSHSSLHGSQMNLANQGMIGNLGGQLGPVRSPQVQHSTFQALSSGISQQP 1330 1340 1350 1360 1370 1380 1320 1330 1340 1350 1360 1370 pF1KB0 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS 1390 1400 1410 1420 1430 1440 1380 1390 1400 1410 1420 1430 pF1KB0 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ 1450 1460 1470 1480 1490 1500 1440 1450 1460 pF1KB0 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC XP_016 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC 1510 1520 1530 1464 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 11:40:07 2016 done: Thu Nov 3 11:40:09 2016 Total Scan time: 16.230 Total Display time: 0.860 Function used was FASTA [36.3.4 Apr, 2011]