FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0170, 1071 aa 1>>>pF1KB0170 1071 - 1071 aa - 1071 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5699+/-0.000579; mu= 19.7699+/- 0.036 mean_var=65.3814+/-12.978, 0's: 0 Z-trim(105.8): 47 B-trim: 50 in 1/48 Lambda= 0.158616 statistics sampled from 13913 (13934) to 13913 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.488), E-opt: 0.2 (0.163), width: 16 Scan time: 11.190 The best scores are: opt bits E(85289) XP_011531399 (OMIM: 602559) PREDICTED: exportin-1 (1071) 7064 1626.6 0 NP_003391 (OMIM: 602559) exportin-1 [Homo sapiens] (1071) 7064 1626.6 0 XP_006712157 (OMIM: 602559) PREDICTED: exportin-1 (1071) 7064 1626.6 0 XP_011531401 (OMIM: 602559) PREDICTED: exportin-1 (1005) 6560 1511.3 0 XP_005264603 (OMIM: 602559) PREDICTED: exportin-1 ( 940) 6194 1427.5 0 XP_005264601 (OMIM: 602559) PREDICTED: exportin-1 (1056) 6172 1422.5 0 XP_011531400 (OMIM: 602559) PREDICTED: exportin-1 (1026) 4167 963.7 0 NP_065801 (OMIM: 607845) exportin-5 [Homo sapiens] (1204) 235 64.0 6.1e-09 >>XP_011531399 (OMIM: 602559) PREDICTED: exportin-1 isof (1071 aa) initn: 7064 init1: 7064 opt: 7064 Z-score: 8727.8 bits: 1626.6 E(85289): 0 Smith-Waterman score: 7064; 100.0% identity (100.0% similar) in 1071 aa overlap (1-1071:1-1071) 10 20 30 40 50 60 pF1KB0 MPAIMTMLADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQRMAQEVLTHLKEHPDAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPAIMTMLADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQRMAQEVLTHLKEHPDAW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 TRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 FSSGQITQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSSGQITQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 IFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQYEEQFVTLFTLTMMQLKQMLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQYEEQFVTLFTLTMMQLKQMLPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 NTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIEKRLNLRETLMEALHYMLLVSEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIEKRLNLRETLMEALHYMLLVSEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 EETEIFKICLEYWNHLAAELYRESPFSTSASPLLSGSQHFDVPPRRQLYLPMLFKVRLLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EETEIFKICLEYWNHLAAELYRESPFSTSASPLLSGSQHFDVPPRRQLYLPMLFKVRLLM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 VSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTERIMTEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTERIMTEKL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 HNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAII 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 ASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 QVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEHLIEKYMLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEHLIEKYMLL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 PNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 YKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVAENFVPPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVAENFVPPL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LDAVLIDYQRNVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDAVLIDYQRNVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 YPEHRTNFFLLLQAVNSHCFPAFLAIPPTQFKLVLDSIIWAFKHTMRNVADTGLQILFTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YPEHRTNFFLLLQAVNSHCFPAFLAIPPTQFKLVLDSIIWAFKHTMRNVADTGLQILFTL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 LQNVAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKIST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQNVAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKIST 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 SLNPGNPVNNQIFLQEYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLNPGNPVNNQIFLQEYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KB0 QIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFNPHEIPEEMCD ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFNPHEIPEEMCD 1030 1040 1050 1060 1070 >>NP_003391 (OMIM: 602559) exportin-1 [Homo sapiens] (1071 aa) initn: 7064 init1: 7064 opt: 7064 Z-score: 8727.8 bits: 1626.6 E(85289): 0 Smith-Waterman score: 7064; 100.0% identity (100.0% similar) in 1071 aa overlap (1-1071:1-1071) 10 20 30 40 50 60 pF1KB0 MPAIMTMLADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQRMAQEVLTHLKEHPDAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MPAIMTMLADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQRMAQEVLTHLKEHPDAW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 TRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 TRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 EKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 FSSGQITQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 FSSGQITQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 IFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQYEEQFVTLFTLTMMQLKQMLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 IFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQYEEQFVTLFTLTMMQLKQMLPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 NTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIEKRLNLRETLMEALHYMLLVSEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 NTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIEKRLNLRETLMEALHYMLLVSEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 EETEIFKICLEYWNHLAAELYRESPFSTSASPLLSGSQHFDVPPRRQLYLPMLFKVRLLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 EETEIFKICLEYWNHLAAELYRESPFSTSASPLLSGSQHFDVPPRRQLYLPMLFKVRLLM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 VSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTERIMTEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTERIMTEKL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 HNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 HNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAII 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 ASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 QVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEHLIEKYMLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEHLIEKYMLL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 PNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 YKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVAENFVPPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 YKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVAENFVPPL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LDAVLIDYQRNVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LDAVLIDYQRNVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 YPEHRTNFFLLLQAVNSHCFPAFLAIPPTQFKLVLDSIIWAFKHTMRNVADTGLQILFTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 YPEHRTNFFLLLQAVNSHCFPAFLAIPPTQFKLVLDSIIWAFKHTMRNVADTGLQILFTL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 LQNVAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKIST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LQNVAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKIST 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 SLNPGNPVNNQIFLQEYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 SLNPGNPVNNQIFLQEYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KB0 QIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFNPHEIPEEMCD ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFNPHEIPEEMCD 1030 1040 1050 1060 1070 >>XP_006712157 (OMIM: 602559) PREDICTED: exportin-1 isof (1071 aa) initn: 7064 init1: 7064 opt: 7064 Z-score: 8727.8 bits: 1626.6 E(85289): 0 Smith-Waterman score: 7064; 100.0% identity (100.0% similar) in 1071 aa overlap (1-1071:1-1071) 10 20 30 40 50 60 pF1KB0 MPAIMTMLADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQRMAQEVLTHLKEHPDAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MPAIMTMLADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQRMAQEVLTHLKEHPDAW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 TRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 FSSGQITQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FSSGQITQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 IFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQYEEQFVTLFTLTMMQLKQMLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQYEEQFVTLFTLTMMQLKQMLPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 NTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIEKRLNLRETLMEALHYMLLVSEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIEKRLNLRETLMEALHYMLLVSEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 EETEIFKICLEYWNHLAAELYRESPFSTSASPLLSGSQHFDVPPRRQLYLPMLFKVRLLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EETEIFKICLEYWNHLAAELYRESPFSTSASPLLSGSQHFDVPPRRQLYLPMLFKVRLLM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 VSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTERIMTEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTERIMTEKL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 HNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAII 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 ASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 QVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEHLIEKYMLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEHLIEKYMLL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 PNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 YKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVAENFVPPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVAENFVPPL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 LDAVLIDYQRNVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LDAVLIDYQRNVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 YPEHRTNFFLLLQAVNSHCFPAFLAIPPTQFKLVLDSIIWAFKHTMRNVADTGLQILFTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YPEHRTNFFLLLQAVNSHCFPAFLAIPPTQFKLVLDSIIWAFKHTMRNVADTGLQILFTL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 LQNVAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKIST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LQNVAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKIST 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 SLNPGNPVNNQIFLQEYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLNPGNPVNNQIFLQEYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KB0 QIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFNPHEIPEEMCD ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFNPHEIPEEMCD 1030 1040 1050 1060 1070 >>XP_011531401 (OMIM: 602559) PREDICTED: exportin-1 isof (1005 aa) initn: 6560 init1: 6560 opt: 6560 Z-score: 8105.0 bits: 1511.3 E(85289): 0 Smith-Waterman score: 6560; 99.9% identity (100.0% similar) in 996 aa overlap (76-1071:10-1005) 50 60 70 80 90 100 pF1KB0 AQEVLTHLKEHPDAWTRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKY .::::::::::::::::::::::::::::: XP_011 MIRGTERKQQYYGLQILENVIKTRWKILPRNQCEGIKKY 10 20 30 110 120 130 140 150 160 pF1KB0 VVGLIIKTSSDPTCVEKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVGLIIKTSSDPTCVEKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQ 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB0 NNMVILKLLSEEVFDFSSGQITQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NNMVILKLLSEEVFDFSSGQITQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHAT 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB0 LETLLRFLNWIPLGYIFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQYEEQFVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LETLLRFLNWIPLGYIFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQYEEQFVT 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB0 LFTLTMMQLKQMLPLNTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIEKRLNLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LFTLTMMQLKQMLPLNTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIEKRLNLRE 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB0 TLMEALHYMLLVSEVEETEIFKICLEYWNHLAAELYRESPFSTSASPLLSGSQHFDVPPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLMEALHYMLLVSEVEETEIFKICLEYWNHLAAELYRESPFSTSASPLLSGSQHFDVPPR 280 290 300 310 320 330 410 420 430 440 450 460 pF1KB0 RQLYLPMLFKVRLLMVSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQLYLPMLFKVRLLMVSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLT 340 350 360 370 380 390 470 480 490 500 510 520 pF1KB0 HLDYVDTERIMTEKLHNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLDYVDTERIMTEKLHNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLL 400 410 420 430 440 450 530 540 550 560 570 580 pF1KB0 GLCEQKRGKDNKAIIASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLCEQKRGKDNKAIIASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMAC 460 470 480 490 500 510 590 600 610 620 630 640 pF1KB0 DTFIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTFIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQT 520 530 540 550 560 570 650 660 670 680 690 700 pF1KB0 DQTVQEHLIEKYMLLPNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQTVQEHLIEKYMLLPNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHP 580 590 600 610 620 630 710 720 730 740 750 760 pF1KB0 FVIQLGRIYLDMLNVYKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVIQLGRIYLDMLNVYKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSR 640 650 660 670 680 690 770 780 790 800 810 820 pF1KB0 SNDPQMVAENFVPPLLDAVLIDYQRNVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNDPQMVAENFVPPLLDAVLIDYQRNVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDA 700 710 720 730 740 750 830 840 850 860 870 880 pF1KB0 VFECTLNMINKDFEEYPEHRTNFFLLLQAVNSHCFPAFLAIPPTQFKLVLDSIIWAFKHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VFECTLNMINKDFEEYPEHRTNFFLLLQAVNSHCFPAFLAIPPTQFKLVLDSIIWAFKHT 760 770 780 790 800 810 890 900 910 920 930 940 pF1KB0 MRNVADTGLQILFTLLQNVAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MRNVADTGLQILFTLLQNVAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASI 820 830 840 850 860 870 950 960 970 980 990 1000 pF1KB0 LAYMFNLVEEGKISTSLNPGNPVNNQIFLQEYVANLLKSAFPHLQDAQVKLFVTGLFSLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAYMFNLVEEGKISTSLNPGNPVNNQIFLQEYVANLLKSAFPHLQDAQVKLFVTGLFSLN 880 890 900 910 920 930 1010 1020 1030 1040 1050 1060 pF1KB0 QDIPAFKEHLRDFLVQIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFNPHEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QDIPAFKEHLRDFLVQIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFNPHEI 940 950 960 970 980 990 1070 pF1KB0 PEEMCD :::::: XP_011 PEEMCD 1000 >>XP_005264603 (OMIM: 602559) PREDICTED: exportin-1 isof (940 aa) initn: 6194 init1: 6194 opt: 6194 Z-score: 7652.8 bits: 1427.5 E(85289): 0 Smith-Waterman score: 6194; 100.0% identity (100.0% similar) in 940 aa overlap (132-1071:1-940) 110 120 130 140 150 160 pF1KB0 IKKYVVGLIIKTSSDPTCVEKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSE :::::::::::::::::::::::::::::: XP_005 MILVQILKQEWPKHWPTFISDIVGASRTSE 10 20 30 170 180 190 200 210 220 pF1KB0 SLCQNNMVILKLLSEEVFDFSSGQITQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLCQNNMVILKLLSEEVFDFSSGQITQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPL 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB0 VHATLETLLRFLNWIPLGYIFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQYEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VHATLETLLRFLNWIPLGYIFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQYEE 100 110 120 130 140 150 290 300 310 320 330 340 pF1KB0 QFVTLFTLTMMQLKQMLPLNTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIEKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QFVTLFTLTMMQLKQMLPLNTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIEKRL 160 170 180 190 200 210 350 360 370 380 390 400 pF1KB0 NLRETLMEALHYMLLVSEVEETEIFKICLEYWNHLAAELYRESPFSTSASPLLSGSQHFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NLRETLMEALHYMLLVSEVEETEIFKICLEYWNHLAAELYRESPFSTSASPLLSGSQHFD 220 230 240 250 260 270 410 420 430 440 450 460 pF1KB0 VPPRRQLYLPMLFKVRLLMVSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VPPRRQLYLPMLFKVRLLMVSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETL 280 290 300 310 320 330 470 480 490 500 510 520 pF1KB0 VYLTHLDYVDTERIMTEKLHNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VYLTHLDYVDTERIMTEKLHNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVI 340 350 360 370 380 390 530 540 550 560 570 580 pF1KB0 KDLLGLCEQKRGKDNKAIIASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KDLLGLCEQKRGKDNKAIIASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQ 400 410 420 430 440 450 590 600 610 620 630 640 pF1KB0 DMACDTFIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DMACDTFIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMI 460 470 480 490 500 510 650 660 670 680 690 700 pF1KB0 GAQTDQTVQEHLIEKYMLLPNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GAQTDQTVQEHLIEKYMLLPNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKA 520 530 540 550 560 570 710 720 730 740 750 760 pF1KB0 VGHPFVIQLGRIYLDMLNVYKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VGHPFVIQLGRIYLDMLNVYKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISG 580 590 600 610 620 630 770 780 790 800 810 820 pF1KB0 WVSRSNDPQMVAENFVPPLLDAVLIDYQRNVPAAREPEVLSTMAIIVNKLGGHITAEIPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WVSRSNDPQMVAENFVPPLLDAVLIDYQRNVPAAREPEVLSTMAIIVNKLGGHITAEIPQ 640 650 660 670 680 690 830 840 850 860 870 880 pF1KB0 IFDAVFECTLNMINKDFEEYPEHRTNFFLLLQAVNSHCFPAFLAIPPTQFKLVLDSIIWA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IFDAVFECTLNMINKDFEEYPEHRTNFFLLLQAVNSHCFPAFLAIPPTQFKLVLDSIIWA 700 710 720 730 740 750 890 900 910 920 930 940 pF1KB0 FKHTMRNVADTGLQILFTLLQNVAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FKHTMRNVADTGLQILFTLLQNVAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTM 760 770 780 790 800 810 950 960 970 980 990 1000 pF1KB0 HASILAYMFNLVEEGKISTSLNPGNPVNNQIFLQEYVANLLKSAFPHLQDAQVKLFVTGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HASILAYMFNLVEEGKISTSLNPGNPVNNQIFLQEYVANLLKSAFPHLQDAQVKLFVTGL 820 830 840 850 860 870 1010 1020 1030 1040 1050 1060 pF1KB0 FSLNQDIPAFKEHLRDFLVQIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FSLNQDIPAFKEHLRDFLVQIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFN 880 890 900 910 920 930 1070 pF1KB0 PHEIPEEMCD :::::::::: XP_005 PHEIPEEMCD 940 >>XP_005264601 (OMIM: 602559) PREDICTED: exportin-1 isof (1056 aa) initn: 6172 init1: 6172 opt: 6172 Z-score: 7624.8 bits: 1422.5 E(85289): 0 Smith-Waterman score: 6933; 98.6% identity (98.6% similar) in 1071 aa overlap (1-1071:1-1056) 10 20 30 40 50 60 pF1KB0 MPAIMTMLADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQRMAQEVLTHLKEHPDAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MPAIMTMLADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQRMAQEVLTHLKEHPDAW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 TRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFD : :::::::::::::::::::::::::::::::::::::::::::: XP_005 E---------------ILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFD 130 140 150 160 190 200 210 220 230 240 pF1KB0 FSSGQITQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FSSGQITQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGY 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB0 IFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQYEEQFVTLFTLTMMQLKQMLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQYEEQFVTLFTLTMMQLKQMLPL 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB0 NTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIEKRLNLRETLMEALHYMLLVSEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIEKRLNLRETLMEALHYMLLVSEV 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB0 EETEIFKICLEYWNHLAAELYRESPFSTSASPLLSGSQHFDVPPRRQLYLPMLFKVRLLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EETEIFKICLEYWNHLAAELYRESPFSTSASPLLSGSQHFDVPPRRQLYLPMLFKVRLLM 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB0 VSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTERIMTEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTERIMTEKL 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB0 HNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAII 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB0 ASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFV 530 540 550 560 570 580 610 620 630 640 650 660 pF1KB0 QVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEHLIEKYMLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEHLIEKYMLL 590 600 610 620 630 640 670 680 690 700 710 720 pF1KB0 PNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNV 650 660 670 680 690 700 730 740 750 760 770 780 pF1KB0 YKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVAENFVPPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVAENFVPPL 710 720 730 740 750 760 790 800 810 820 830 840 pF1KB0 LDAVLIDYQRNVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDAVLIDYQRNVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEE 770 780 790 800 810 820 850 860 870 880 890 900 pF1KB0 YPEHRTNFFLLLQAVNSHCFPAFLAIPPTQFKLVLDSIIWAFKHTMRNVADTGLQILFTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YPEHRTNFFLLLQAVNSHCFPAFLAIPPTQFKLVLDSIIWAFKHTMRNVADTGLQILFTL 830 840 850 860 870 880 910 920 930 940 950 960 pF1KB0 LQNVAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKIST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQNVAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKIST 890 900 910 920 930 940 970 980 990 1000 1010 1020 pF1KB0 SLNPGNPVNNQIFLQEYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLNPGNPVNNQIFLQEYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLV 950 960 970 980 990 1000 1030 1040 1050 1060 1070 pF1KB0 QIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFNPHEIPEEMCD ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFNPHEIPEEMCD 1010 1020 1030 1040 1050 >>XP_011531400 (OMIM: 602559) PREDICTED: exportin-1 isof (1026 aa) initn: 4167 init1: 4167 opt: 4167 Z-score: 5145.3 bits: 963.7 E(85289): 0 Smith-Waterman score: 6667; 95.8% identity (95.8% similar) in 1071 aa overlap (1-1071:1-1026) 10 20 30 40 50 60 pF1KB0 MPAIMTMLADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQRMAQEVLTHLKEHPDAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPAIMTMLADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQRMAQEVLTHLKEHPDAW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 TRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 FSSGQITQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSSGQITQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 IFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQYEEQFVTLFTLTMMQLKQMLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQYEEQFVTLFTLTMMQLKQMLPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 NTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIEKRLNLRETLMEALHYMLLVSEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIEKRLNLRETLMEALHYMLLVSEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 EETEIFKICLEYWNHLAAELYRESPFSTSASPLLSGSQHFDVPPRRQLYLPMLFKVRLLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EETEIFKICLEYWNHLAAELYRESPFSTSASPLLSGSQHFDVPPRRQLYLPMLFKVRLLM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 VSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTERIMTEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTERIMTEKL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 HNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAII 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 ASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 QVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEHLIEKYMLL ::::::::::::::::::::::::::::: XP_011 QVQVGEVMPFIDEILNNINTIICDLQPQQ------------------------------- 610 620 670 680 690 700 710 720 pF1KB0 PNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNV :::::::::::::::::::::::::::::::::::::::::::::: XP_011 --------------NVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNV 630 640 650 660 670 730 740 750 760 770 780 pF1KB0 YKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVAENFVPPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVAENFVPPL 680 690 700 710 720 730 790 800 810 820 830 840 pF1KB0 LDAVLIDYQRNVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDAVLIDYQRNVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEE 740 750 760 770 780 790 850 860 870 880 890 900 pF1KB0 YPEHRTNFFLLLQAVNSHCFPAFLAIPPTQFKLVLDSIIWAFKHTMRNVADTGLQILFTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YPEHRTNFFLLLQAVNSHCFPAFLAIPPTQFKLVLDSIIWAFKHTMRNVADTGLQILFTL 800 810 820 830 840 850 910 920 930 940 950 960 pF1KB0 LQNVAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKIST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQNVAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKIST 860 870 880 890 900 910 970 980 990 1000 1010 1020 pF1KB0 SLNPGNPVNNQIFLQEYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLNPGNPVNNQIFLQEYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLV 920 930 940 950 960 970 1030 1040 1050 1060 1070 pF1KB0 QIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFNPHEIPEEMCD ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFNPHEIPEEMCD 980 990 1000 1010 1020 >>NP_065801 (OMIM: 607845) exportin-5 [Homo sapiens] (1204 aa) initn: 193 init1: 113 opt: 235 Z-score: 281.4 bits: 64.0 E(85289): 6.1e-09 Smith-Waterman score: 311; 21.3% identity (51.8% similar) in 898 aa overlap (68-875:56-892) 40 50 60 70 80 90 pF1KB0 GEGAQQRMAQEVLTHLKEHPDAWTRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRN : .: ....::::::.:.: ::. . : NP_065 TQRYRLEALKFCEEFKEKCPICVPCGLRLAEKTQVAIVRHFGLQILEHVVKFRWNGMSRL 30 40 50 60 70 80 100 110 120 130 140 150 pF1KB0 QCEGIKKYVVGLIIKTSSDPTCVEKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGAS . .:. :. :: . . . .:.:. :. :.:...:.:::.::: .. .. : NP_065 EKVYLKNSVMELIANGTLN--ILEEENHIKDALSRIVVEMIKREWPQHWPDMLIELDTLS 90 100 110 120 130 140 160 170 180 190 200 210 pF1KB0 RTSESLCQNNMVILKLLSEEVFDFSSGQITQVKSKHLKDSMCNEFSQIFQ-LCQFVMENS . .:. . : :: :.:.: :.. . . . ..... ... .::. : . ..:: NP_065 KQGETQTELVMFILLRLAEDVVTFQT--LPPQRRRDIQQTLTQNMERIFSFLLNTLQENV 150 160 170 180 190 200 220 230 240 250 pF1KB0 QNAPLVH-----------------ATLETLLRFLNWIPLGYIF--ETKLISTLIYKFLNV .. :. :.:.:: ...:. ...: . ::. : .:: NP_065 NKYQQVKTDTSQESKAQANCRVGVAALNTLAGYIDWVSMSHITAENCKLLEILCL-LLNE 210 220 230 240 250 260 260 270 280 290 300 310 pF1KB0 PMFRNVSLKCLTEIAGVSVSQYEEQFVTLFTLTMMQLKQMLPLNTNIRLAYSNGKDDEQN .. . .:: :: .. :.. . . . .. .: . . : ..: ... NP_065 QELQLGAAECLL-IAVSRKGKLEDRKPLMVLFGDVAMHYIL---SAAQTADGGGLVEKHY 270 280 290 300 310 320 330 340 350 360 370 pF1KB0 -FIQNLSLFLCTFLKEHDQLIEKRLNLRETLMEALHYMLLVSEVEETEIFKICLEYWNHL :.. : ::.. .:: .:. : :.:: : .: . . NP_065 VFLKRLCQVLCAL---GNQLC--------ALLGAD------SDVETPSNFG---KYLESF 320 330 340 350 380 390 400 410 420 430 pF1KB0 AAELYRESPFSTSASPLLSGSQ-HFDVPPRRQLYL---PMLFKVRLLMVSRMAKPEEVLV : . : : :.. . :. . .. : : : : ... . . .:. : . NP_065 LAFTTHPSQFLRSSTQMTWGALFRHEILSRDPLLLAIIPKYLRASMTNLVKMGFPSK--- 360 370 380 390 400 410 440 450 460 470 480 pF1KB0 VENDQGEVVR-EFMKDTDSINLYKNMR----ETLVYLTHLDYVDTERIMTEKLHNQVNGT ... . : : .: .: : .... : :.. .:: . .. : :. :.. : NP_065 TDSPSCEYSRFDFDSDEDFNAFFNSSRAQQGEVMRLACRLDPKTSFQMAGEWLKYQLS-T 420 430 440 450 460 470 490 500 510 520 pF1KB0 EWSWKNLNTLCWAIGSISGAM---------HEEDEKRFLVTVI--------------KDL . ..:. : :.:. :.. . : :: .:: .: NP_065 FLDAGSVNS-CSAVGTGEGSLCSVFSPSFVQWEAMTLFLESVITQMFRTLNREEIPVNDG 480 490 500 510 520 530 530 540 550 560 570 pF1KB0 LGLCEQKRGKDNK-AIIASNIMYIVGQYPRFLRAHWKFLKTVVNKLF-----EFMHETHD . : .. . :.: .: : .. :. :. . .:: : .::: : ..:.. NP_065 IELLQMVLNFDTKDPLILSCVLTNVSALFPFVTYRPEFLPQVFSKLFSSVTFETVEESKA 540 550 560 570 580 590 580 590 600 610 620 pF1KB0 -------GVQDMACDTFIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICD---LQPQ .:. ::...::. :: . :. :.: .: . :... .. . : . NP_065 PRTRAVRNVRRHACSSIIKM---CR-DYPQL----VLPNFDMLYNHVKQLLSNELLLTQM 600 610 620 630 640 630 640 650 660 670 680 pF1KB0 QVHTFYEAVGYMIGAQ-TDQTVQEHLIEKYMLLPNQVWDSIIQQATKNVDILKDPETVKQ . ...::. .:. : . :. ..:. : ..: : :. . .:.: : NP_065 EKCALMEAL-VLISNQFKNYERQKVFLEELMAPVASIWLS--QDMHR---VLSD---VDA 650 660 670 680 690 690 700 710 720 730 pF1KB0 LGSILKTNVRACK-AVGHPFVIQLGRIYL---DMLNVYK--CLSENISAAIQANGEMV-- . . . :. ..: .. : .. .:. . ..:.: : : .. : .:.: .: NP_065 FIAYVGTDQKSCDPGLEDPCGLNRARMSFCVYSILGVVKRTCWPTDLEEA-KAGGFVVGY 700 710 720 730 740 750 740 750 760 770 780 790 pF1KB0 --TKQPLIRSMRTVKRETLKLISGWVS--RSND----PQMVAENFVPPLLDAV-LIDYQR . .:..:. : .. :::... .. :... :.:.:. .. :. :. ..: .. NP_065 TSSGNPIFRNPCT--EQILKLLDNLLALIRTHNTLYAPEMLAK-MAEPFTKALDMLDAEK 760 770 780 790 800 810 800 810 820 830 840 850 pF1KB0 NVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEEYPEHRTNFFL .. . .: : : . .. ..:....: .....: : . .:. NP_065 SAILGLPQPLLELNDSPVFKT---VLERMQRFFSTLYENCFHILGK---AGPSMQQDFYT 820 830 840 850 860 860 870 880 890 900 pF1KB0 ---LLQAVNSHCFPAFLAIPPTQFKLVLDSIIWAFKHTMRNVADTGLQILFTLLQNVAQE : . : : . :: ... .: NP_065 VEDLATQLLSSAFVNLNNIPDYRLRPMLRVFVKPLVLFCPPEHYEALVSPILGPLFTYLH 870 880 890 900 910 920 1071 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:01:46 2016 done: Fri Nov 4 02:01:48 2016 Total Scan time: 11.190 Total Display time: 0.380 Function used was FASTA [36.3.4 Apr, 2011]