FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0401, 171 aa 1>>>pF1KB0401 171 - 171 aa - 171 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5745+/-0.000942; mu= 11.4537+/- 0.057 mean_var=85.0667+/-17.146, 0's: 0 Z-trim(106.4): 80 B-trim: 4 in 1/48 Lambda= 0.139058 statistics sampled from 8860 (8945) to 8860 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.275), width: 16 Scan time: 1.360 The best scores are: opt bits E(32554) CCDS11830.1 MYL12A gene_id:10627|Hs108|chr18 ( 171) 1136 237.4 3.3e-63 CCDS77145.1 MYL12A gene_id:10627|Hs108|chr18 ( 177) 1136 237.4 3.4e-63 CCDS11831.1 MYL12B gene_id:103910|Hs108|chr18 ( 172) 1108 231.8 1.6e-61 CCDS13276.1 MYL9 gene_id:10398|Hs108|chr20 ( 172) 1072 224.5 2.4e-59 CCDS31901.1 MYL2 gene_id:4633|Hs108|chr12 ( 166) 634 136.7 6.7e-33 CCDS43197.1 MYL5 gene_id:4636|Hs108|chr4 ( 173) 615 132.9 9.7e-32 CCDS10677.1 MYLPF gene_id:29895|Hs108|chr16 ( 169) 610 131.9 1.9e-31 CCDS5478.1 MYL7 gene_id:58498|Hs108|chr7 ( 175) 559 121.6 2.4e-28 CCDS34713.1 MYL10 gene_id:93408|Hs108|chr7 ( 226) 492 108.3 3.2e-24 CCDS9892.1 CALM1 gene_id:801|Hs108|chr14 ( 149) 401 89.9 7.2e-19 CCDS1832.1 CALM2 gene_id:805|Hs108|chr2 ( 149) 401 89.9 7.2e-19 CCDS33061.1 CALM3 gene_id:808|Hs108|chr19 ( 149) 401 89.9 7.2e-19 CCDS7069.1 CALML3 gene_id:810|Hs108|chr10 ( 149) 378 85.3 1.8e-17 CCDS13277.1 MYL9 gene_id:10398|Hs108|chr20 ( 118) 360 81.6 1.8e-16 CCDS14716.1 CETN2 gene_id:1069|Hs108|chrX ( 172) 291 67.9 3.6e-12 CCDS11820.1 CETN1 gene_id:1068|Hs108|chr18 ( 172) 282 66.1 1.2e-11 CCDS10226.2 CALML4 gene_id:91860|Hs108|chr15 ( 196) 276 64.9 3.2e-11 >>CCDS11830.1 MYL12A gene_id:10627|Hs108|chr18 (171 aa) initn: 1136 init1: 1136 opt: 1136 Z-score: 1248.3 bits: 237.4 E(32554): 3.3e-63 Smith-Waterman score: 1136; 100.0% identity (100.0% similar) in 171 aa overlap (1-171:1-171) 10 20 30 40 50 60 pF1KB0 MSSKRTKTKTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MSSKRTKTKTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 GKNPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 GKNPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQED 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 YLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 YLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD 130 140 150 160 170 >>CCDS77145.1 MYL12A gene_id:10627|Hs108|chr18 (177 aa) initn: 1136 init1: 1136 opt: 1136 Z-score: 1248.1 bits: 237.4 E(32554): 3.4e-63 Smith-Waterman score: 1136; 100.0% identity (100.0% similar) in 171 aa overlap (1-171:7-177) 10 20 30 40 50 pF1KB0 MSSKRTKTKTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLH :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 MDLTTTMSSKRTKTKTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLH 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB0 DMLASLGKNPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 DMLASLGKNPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEAT 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 GTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 GTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD 130 140 150 160 170 >>CCDS11831.1 MYL12B gene_id:103910|Hs108|chr18 (172 aa) initn: 1077 init1: 1077 opt: 1108 Z-score: 1217.9 bits: 231.8 E(32554): 1.6e-61 Smith-Waterman score: 1108; 97.7% identity (98.8% similar) in 172 aa overlap (1-171:1-172) 10 20 30 40 50 pF1KB0 MSSKRTKTKT-KKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLAS ::::..:::: ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MSSKKAKTKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLAS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB0 LGKNPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQE ::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LGKNPTDAYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 DYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 DYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD 130 140 150 160 170 >>CCDS13276.1 MYL9 gene_id:10398|Hs108|chr20 (172 aa) initn: 1042 init1: 1042 opt: 1072 Z-score: 1178.8 bits: 224.5 E(32554): 2.4e-59 Smith-Waterman score: 1072; 93.0% identity (98.8% similar) in 172 aa overlap (1-171:1-172) 10 20 30 40 50 pF1KB0 MSSKRTKTKT-KKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLAS :::::.:.:: ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MSSKRAKAKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLAS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB0 LGKNPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQE ::::::::::..::.:::::::::::::::::::::::::::::::::::::::.: :.: CCDS13 LGKNPTDEYLEGMMSEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 DYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD :.:::::::::::::::::::.::::::::::::::.::::::::::::::: CCDS13 DHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILKHGAKDKDD 130 140 150 160 170 >>CCDS31901.1 MYL2 gene_id:4633|Hs108|chr12 (166 aa) initn: 627 init1: 388 opt: 634 Z-score: 704.2 bits: 136.7 E(32554): 6.7e-33 Smith-Waterman score: 634; 57.7% identity (84.7% similar) in 163 aa overlap (9-170:5-166) 10 20 30 40 50 60 pF1KB0 MSSKRTKTKTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASL :.::: :.::::.::.:.:::::::::...::::::::::.::.: .:.: CCDS31 MAPKKAKKRAGGANSNVFSMFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAAL 10 20 30 40 50 70 80 90 100 110 pF1KB0 GK-NPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQE :. : .: .: :..:::::::::.:::::::::.:.:::..: ::: :: :. :... CCDS31 GRVNVKNEEIDEMIKEAPGPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 DYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD ::.::.:::...::. ::::... : : ::..: ....:. :: ..:: CCDS31 DYVREMLTTQAERFSKEEVDQMFAAFPPDVTGNLDYKNLVHIITHG-EEKD 120 130 140 150 160 >>CCDS43197.1 MYL5 gene_id:4636|Hs108|chr4 (173 aa) initn: 586 init1: 341 opt: 615 Z-score: 683.3 bits: 132.9 E(32554): 9.7e-32 Smith-Waterman score: 615; 53.8% identity (80.3% similar) in 173 aa overlap (1-170:1-173) 10 20 30 40 50 pF1KB0 MSSKRTKTKTKK--RPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLA :.:..:: : : :::.::::. :.:.:::::::::...:::::::::::::.: : CCDS43 MASRKTKKKEGGALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDTYA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB0 SLGK-NPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTI :::: : :. ::::..:: :::::::::..:::::.::: :..: ::: .: .. : : CCDS43 SLGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 QEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD ...:...:: ...:..: ::::.... : :: ::..: .. .. :: . .. CCDS43 NKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE 130 140 150 160 170 >>CCDS10677.1 MYLPF gene_id:29895|Hs108|chr16 (169 aa) initn: 584 init1: 369 opt: 610 Z-score: 678.0 bits: 131.9 E(32554): 1.9e-31 Smith-Waterman score: 610; 55.8% identity (80.8% similar) in 172 aa overlap (1-170:1-169) 10 20 30 40 50 60 pF1KB0 MSSKRTKTKTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASL :. ::.: .: . ..:.::.::::.:::::::::..:::::::.::::::.: .:.. CCDS10 MAPKRAKRRTV---EGGSSSVFSMFDQTQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAAM 10 20 30 40 50 70 80 90 100 110 pF1KB0 GK-NPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQE :. : .: :::::.:: ::::::.:::::::::.:.:::::: .:: .: :. :::.. CCDS10 GRLNVKNEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIKK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 DYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHG-AKDKDD .:.:::::. :::..::. ... : : :: .: .. .. :: :::.. CCDS10 KFLEELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAKDQE 120 130 140 150 160 >>CCDS5478.1 MYL7 gene_id:58498|Hs108|chr7 (175 aa) initn: 570 init1: 338 opt: 559 Z-score: 622.5 bits: 121.6 E(32554): 2.4e-28 Smith-Waterman score: 559; 48.6% identity (78.3% similar) in 175 aa overlap (1-170:1-175) 10 20 30 40 50 pF1KB0 MSSKRTKTKTK----KRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDM :.:... :. : :. ::..::::.::.:.:::::::::. :::::::.: : ::.. CCDS54 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB0 LASLGK-NPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATG ..::: . .: ::::..:. ::::::.:::.:::::::::::..: .:: :: . : CCDS54 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 TIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD ....: ...:: :..:.:. ::.... .:.: ::..: . :. :: . .. CCDS54 VVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE 130 140 150 160 170 >>CCDS34713.1 MYL10 gene_id:93408|Hs108|chr7 (226 aa) initn: 485 init1: 359 opt: 492 Z-score: 548.3 bits: 108.3 E(32554): 3.2e-24 Smith-Waterman score: 532; 46.5% identity (67.7% similar) in 198 aa overlap (9-170:30-226) 10 20 30 pF1KB0 MSSKRTKTKTKKRPQ-RATSNVFAMFDQSQIQEFKE--- ...:: . :.::::.:::::::::::: CCDS34 MLLRLVSNSWPQVILPPRPPKVLGLQAPRRARKRAEGTASSNVFSMFDQSQIQEFKESLA 10 20 30 40 50 60 40 50 60 pF1KB0 -------------------------------AFNMIDQNRDGFIDKEDLHDMLASLGK-N ::...:::::::::::::.: .:.::. : CCDS34 LSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRIN 70 80 90 100 110 120 70 80 90 100 110 120 pF1KB0 PTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLR .: :.::..:::::::::.:::::::::.:::::..: .:: :: :. : .. : .. CCDS34 VKNEELEAMVKEAPGPINFTVFLTMFGEKLKGTDPEETILHAFKVFDTEGKGFVKADVIK 130 140 150 160 170 180 130 140 150 160 170 pF1KB0 ELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD : : :..:::..::: ... : : ::..: .. .. :: ..:: CCDS34 EKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVITHG-EEKD 190 200 210 220 >>CCDS9892.1 CALM1 gene_id:801|Hs108|chr14 (149 aa) initn: 421 init1: 246 opt: 401 Z-score: 452.2 bits: 89.9 E(32554): 7.2e-19 Smith-Waterman score: 401; 45.2% identity (73.3% similar) in 146 aa overlap (24-162:1-146) 10 20 30 40 50 pF1KB0 MSSKRTKTKTKKRPQRATSNVFAMFDQ---SQIQEFKEAFNMIDQNRDGFIDKEDLHDML : :: :: ::::::...:.. :: : ..: .. CCDS98 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVM 10 20 30 60 70 80 90 100 110 pF1KB0 ASLGKNPTDEYLDAMMNEAP----GPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEA :::.:::. :. :.::. : :.: ::::...:.. :: :. ::.:: ::... CCDS98 RSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDG 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB0 TGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD .: :. ::...:..:...:::::::. ::: :: :. :: ::.... CCDS98 NGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 100 110 120 130 140 171 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:49:40 2016 done: Sat Nov 5 11:49:41 2016 Total Scan time: 1.360 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]