FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0410, 822 aa 1>>>pF1KB0410 822 - 822 aa - 822 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5940+/-0.000392; mu= 21.1059+/- 0.025 mean_var=101.1861+/-20.608, 0's: 0 Z-trim(115.0): 6 B-trim: 403 in 1/52 Lambda= 0.127501 statistics sampled from 25124 (25127) to 25124 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.295), width: 16 Scan time: 12.900 The best scores are: opt bits E(85289) NP_036336 (OMIM: 604892) general transcription fac ( 822) 5575 1036.7 0 XP_016870806 (OMIM: 604892) PREDICTED: general tra ( 754) 4881 909.0 0 XP_016870807 (OMIM: 604892) PREDICTED: general tra ( 234) 936 182.8 1.5e-45 >>NP_036336 (OMIM: 604892) general transcription factor (822 aa) initn: 5575 init1: 5575 opt: 5575 Z-score: 5543.5 bits: 1036.7 E(85289): 0 Smith-Waterman score: 5575; 100.0% identity (100.0% similar) in 822 aa overlap (1-822:1-822) 10 20 30 40 50 60 pF1KB0 MNTADQARVGPADDGPAPSGEEEGEGGGEAGGKEPAADAAPGPSAAFRLMVTRREPAVKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MNTADQARVGPADDGPAPSGEEEGEGGGEAGGKEPAADAAPGPSAAFRLMVTRREPAVKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 QYAVSGLEPLAWSEDHRVSVSTARSIAVLELICDVHNPGQDLVIHRTSVPAPLNSCLLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 QYAVSGLEPLAWSEDHRVSVSTARSIAVLELICDVHNPGQDLVIHRTSVPAPLNSCLLKV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 GSKTEVAECKEKFAASKDPTVSQTFMLDRVFNPEGKALPPMRGFKYTSWSPMGCDANGRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 GSKTEVAECKEKFAASKDPTVSQTFMLDRVFNPEGKALPPMRGFKYTSWSPMGCDANGRC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 LLAALTMDNRLTIQANLNRLQWVQLVDLTEIYGERLYETSYRLSKNEAPEGNLGDFAEFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LLAALTMDNRLTIQANLNRLQWVQLVDLTEIYGERLYETSYRLSKNEAPEGNLGDFAEFQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RRHSMQTPVRMEWSGICTTQQVKHNNECRDVGSVLLAVLFENGNIAVWQFQLPFVGKESI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 RRHSMQTPVRMEWSGICTTQQVKHNNECRDVGSVLLAVLFENGNIAVWQFQLPFVGKESI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 SSCNTIESGITSPSVLFWWEYEHNNRKMSGLIVGSAFGPIKILPVNLKAVKGYFTLRQPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 SSCNTIESGITSPSVLFWWEYEHNNRKMSGLIVGSAFGPIKILPVNLKAVKGYFTLRQPV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 ILWKEMDQLPVHSIKCVPLYHPYQKCSCSLVVAARGSYVFWCLLLISKAGLNVHNSHVTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 ILWKEMDQLPVHSIKCVPLYHPYQKCSCSLVVAARGSYVFWCLLLISKAGLNVHNSHVTG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 LHSLPIVSMTADKQNGTVYTCSSDGKVRQLIPIFTDVALKFEHQLIKLSDVFGSVRTHGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LHSLPIVSMTADKQNGTVYTCSSDGKVRQLIPIFTDVALKFEHQLIKLSDVFGSVRTHGI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 AVSPCGAYLAIITTEGMINGLHPVNKNYQVQFVTLKTFEEAAAQLLESSVQNLFKQVDLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 AVSPCGAYLAIITTEGMINGLHPVNKNYQVQFVTLKTFEEAAAQLLESSVQNLFKQVDLI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 DLVRWKILKDKHIPQFLQEALEKKIESSGVTYFWRFKLFLLRILYQSMQKTPSEALWKPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 DLVRWKILKDKHIPQFLQEALEKKIESSGVTYFWRFKLFLLRILYQSMQKTPSEALWKPT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 HEDSKILLVDSPGMGNADDEQQEEGTSSKQVVKQGLQERSKEGDVEEPTDDSLPTTGDAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 HEDSKILLVDSPGMGNADDEQQEEGTSSKQVVKQGLQERSKEGDVEEPTDDSLPTTGDAG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 GREPMEEKLLEIQGKIEAVEMHLTREHMKRVLGEVYLHTWITENTSIPTRGLCNFLMSDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 GREPMEEKLLEIQGKIEAVEMHLTREHMKRVLGEVYLHTWITENTSIPTRGLCNFLMSDE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 EYDDRTARVLIGHISKKMNKQTFPEHCSLCKEILPFTDRKQAVCSNGHIWLRCFLTYQSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 EYDDRTARVLIGHISKKMNKQTFPEHCSLCKEILPFTDRKQAVCSNGHIWLRCFLTYQSC 730 740 750 760 770 780 790 800 810 820 pF1KB0 QSLIYRRCLLHDSIARHPAPEDPDWIKRLLQSPCPFCDSPVF :::::::::::::::::::::::::::::::::::::::::: NP_036 QSLIYRRCLLHDSIARHPAPEDPDWIKRLLQSPCPFCDSPVF 790 800 810 820 >>XP_016870806 (OMIM: 604892) PREDICTED: general transcr (754 aa) initn: 4877 init1: 4877 opt: 4881 Z-score: 4854.0 bits: 909.0 E(85289): 0 Smith-Waterman score: 4881; 98.8% identity (99.5% similar) in 739 aa overlap (1-736:1-739) 10 20 30 40 50 60 pF1KB0 MNTADQARVGPADDGPAPSGEEEGEGGGEAGGKEPAADAAPGPSAAFRLMVTRREPAVKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNTADQARVGPADDGPAPSGEEEGEGGGEAGGKEPAADAAPGPSAAFRLMVTRREPAVKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 QYAVSGLEPLAWSEDHRVSVSTARSIAVLELICDVHNPGQDLVIHRTSVPAPLNSCLLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QYAVSGLEPLAWSEDHRVSVSTARSIAVLELICDVHNPGQDLVIHRTSVPAPLNSCLLKV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 GSKTEVAECKEKFAASKDPTVSQTFMLDRVFNPEGKALPPMRGFKYTSWSPMGCDANGRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSKTEVAECKEKFAASKDPTVSQTFMLDRVFNPEGKALPPMRGFKYTSWSPMGCDANGRC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 LLAALTMDNRLTIQANLNRLQWVQLVDLTEIYGERLYETSYRLSKNEAPEGNLGDFAEFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLAALTMDNRLTIQANLNRLQWVQLVDLTEIYGERLYETSYRLSKNEAPEGNLGDFAEFQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RRHSMQTPVRMEWSGICTTQQVKHNNECRDVGSVLLAVLFENGNIAVWQFQLPFVGKESI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRHSMQTPVRMEWSGICTTQQVKHNNECRDVGSVLLAVLFENGNIAVWQFQLPFVGKESI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 SSCNTIESGITSPSVLFWWEYEHNNRKMSGLIVGSAFGPIKILPVNLKAVKGYFTLRQPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSCNTIESGITSPSVLFWWEYEHNNRKMSGLIVGSAFGPIKILPVNLKAVKGYFTLRQPV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 ILWKEMDQLPVHSIKCVPLYHPYQKCSCSLVVAARGSYVFWCLLLISKAGLNVHNSHVTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILWKEMDQLPVHSIKCVPLYHPYQKCSCSLVVAARGSYVFWCLLLISKAGLNVHNSHVTG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 LHSLPIVSMTADKQNGTVYTCSSDGKVRQLIPIFTDVALKFEHQLIKLSDVFGSVRTHGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHSLPIVSMTADKQNGTVYTCSSDGKVRQLIPIFTDVALKFEHQLIKLSDVFGSVRTHGI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 AVSPCGAYLAIITTEGMINGLHPVNKNYQVQFVTLKTFEEAAAQLLESSVQNLFKQVDLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVSPCGAYLAIITTEGMINGLHPVNKNYQVQFVTLKTFEEAAAQLLESSVQNLFKQVDLI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 DLVRWKILKDKHIPQFLQEALEKKIESSGVTYFWRFKLFLLRILYQSMQKTPSEALWKPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLVRWKILKDKHIPQFLQEALEKKIESSGVTYFWRFKLFLLRILYQSMQKTPSEALWKPT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 HEDSKILLVDSPGMGNADDEQQEEGTSSKQVVKQGLQERSKEGDVEEPTDDSLPTTGDAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HEDSKILLVDSPGMGNADDEQQEEGTSSKQVVKQGLQERSKEGDVEEPTDDSLPTTGDAG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 GREPMEEKLLEIQGKIEAVEMHLTREHMKRVLGEVYLHTWITENTSIPTRGLCNFLMSDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GREPMEEKLLEIQGKIEAVEMHLTREHMKRVLGEVYLHTWITENTSIPTRGLCNFLMSDE 670 680 690 700 710 720 730 740 750 760 770 pF1KB0 EYDDRTAR---VLIGHISKKMNKQTFPEHCSLCKEILPFTDRKQAVCSNGHIWLRCFLTY :::::::: .:... .: XP_016 EYDDRTARNSEILVSEATKTRQVIRFWFSEQFSP 730 740 750 >>XP_016870807 (OMIM: 604892) PREDICTED: general transcr (234 aa) initn: 936 init1: 936 opt: 936 Z-score: 938.7 bits: 182.8 E(85289): 1.5e-45 Smith-Waterman score: 936; 100.0% identity (100.0% similar) in 141 aa overlap (1-141:1-141) 10 20 30 40 50 60 pF1KB0 MNTADQARVGPADDGPAPSGEEEGEGGGEAGGKEPAADAAPGPSAAFRLMVTRREPAVKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNTADQARVGPADDGPAPSGEEEGEGGGEAGGKEPAADAAPGPSAAFRLMVTRREPAVKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 QYAVSGLEPLAWSEDHRVSVSTARSIAVLELICDVHNPGQDLVIHRTSVPAPLNSCLLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QYAVSGLEPLAWSEDHRVSVSTARSIAVLELICDVHNPGQDLVIHRTSVPAPLNSCLLKV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 GSKTEVAECKEKFAASKDPTVSQTFMLDRVFNPEGKALPPMRGFKYTSWSPMGCDANGRC ::::::::::::::::::::: XP_016 GSKTEVAECKEKFAASKDPTVLIGHISKKMNKQTFPEHCSLCKEILPFTDRKQAVCSNGH 130 140 150 160 170 180 >-- initn: 693 init1: 693 opt: 693 Z-score: 697.1 bits: 138.1 E(85289): 4.3e-32 Smith-Waterman score: 693; 100.0% identity (100.0% similar) in 93 aa overlap (730-822:142-234) 700 710 720 730 740 750 pF1KB0 WITENTSIPTRGLCNFLMSDEEYDDRTARVLIGHISKKMNKQTFPEHCSLCKEILPFTDR :::::::::::::::::::::::::::::: XP_016 PLNSCLLKVGSKTEVAECKEKFAASKDPTVLIGHISKKMNKQTFPEHCSLCKEILPFTDR 120 130 140 150 160 170 760 770 780 790 800 810 pF1KB0 KQAVCSNGHIWLRCFLTYQSCQSLIYRRCLLHDSIARHPAPEDPDWIKRLLQSPCPFCDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQAVCSNGHIWLRCFLTYQSCQSLIYRRCLLHDSIARHPAPEDPDWIKRLLQSPCPFCDS 180 190 200 210 220 230 820 pF1KB0 PVF ::: XP_016 PVF 822 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:46:51 2016 done: Sat Nov 5 16:46:53 2016 Total Scan time: 12.900 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]