FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0411, 467 aa
1>>>pF1KB0411 467 - 467 aa - 467 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.8144+/-0.00144; mu= 5.7469+/- 0.083
mean_var=280.1879+/-61.827, 0's: 0 Z-trim(106.3): 485 B-trim: 0 in 0/50
Lambda= 0.076621
statistics sampled from 8324 (8909) to 8324 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.274), width: 16
Scan time: 2.960
The best scores are: opt bits E(32554)
CCDS7166.1 MAP3K8 gene_id:1326|Hs108|chr10 ( 467) 3127 360.2 2.7e-99
CCDS14631.1 STK26 gene_id:51765|Hs108|chrX ( 416) 488 68.4 1.7e-11
CCDS32001.1 STK24 gene_id:8428|Hs108|chr13 ( 431) 479 67.4 3.4e-11
CCDS9488.1 STK24 gene_id:8428|Hs108|chr13 ( 443) 479 67.4 3.4e-11
>>CCDS7166.1 MAP3K8 gene_id:1326|Hs108|chr10 (467 aa)
initn: 3127 init1: 3127 opt: 3127 Z-score: 1896.1 bits: 360.2 E(32554): 2.7e-99
Smith-Waterman score: 3127; 100.0% identity (100.0% similar) in 467 aa overlap (1-467:1-467)
10 20 30 40 50 60
pF1KB0 MEYMSTGSDNKEEIDLLIKHLNVSDVIDIMENLYASEEPAVYEPSLMTMCQDSNQNDERS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS71 MEYMSTGSDNKEEIDLLIKHLNVSDVIDIMENLYASEEPAVYEPSLMTMCQDSNQNDERS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 KSLLLSGQEVPWLSSVRYGTVEDLLAFANHISNTAKHFYGQRPQESGILLNMVITPQNGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS71 KSLLLSGQEVPWLSSVRYGTVEDLLAFANHISNTAKHFYGQRPQESGILLNMVITPQNGR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 YQIDSDVLLIPWKLTYRNIGSDFIPRGAFGKVYLAQDIKTKKRMACKLIPVDQFKPSDVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS71 YQIDSDVLLIPWKLTYRNIGSDFIPRGAFGKVYLAQDIKTKKRMACKLIPVDQFKPSDVE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 IQACFRHENIAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKHVLKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS71 IQACFRHENIAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKHVLKG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 LDFLHSKKVIHHDIKPSNIVFMSTKAVLVDFGLSVQMTEDVYFPKDLRGTEIYMSPEVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS71 LDFLHSKKVIHHDIKPSNIVFMSTKAVLVDFGLSVQMTEDVYFPKDLRGTEIYMSPEVIL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 CRGHSTKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQAPPLEDIADDCSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS71 CRGHSTKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQAPPLEDIADDCSPG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 MRELIEASLERNPNHRPRAADLLKHEALNPPREDQPRCQSLDSALLERKRLLSRKELELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS71 MRELIEASLERNPNHRPRAADLLKHEALNPPREDQPRCQSLDSALLERKRLLSRKELELP
370 380 390 400 410 420
430 440 450 460
pF1KB0 ENIADSSCTGSTEESEMLKRQRSLYIDLGALAGYFNLVRGPPTLEYG
:::::::::::::::::::::::::::::::::::::::::::::::
CCDS71 ENIADSSCTGSTEESEMLKRQRSLYIDLGALAGYFNLVRGPPTLEYG
430 440 450 460
>>CCDS14631.1 STK26 gene_id:51765|Hs108|chrX (416 aa)
initn: 198 init1: 163 opt: 488 Z-score: 320.1 bits: 68.4 E(32554): 1.7e-11
Smith-Waterman score: 488; 36.0% identity (67.2% similar) in 250 aa overlap (144-386:30-272)
120 130 140 150 160 170
pF1KB0 ITPQNGRYQIDSDVLLIPWKLTYRNIGSDFIPRGAFGKVYLAQDIKTKKRMACKLIPV--
: .:.::.:. . : .:.. .: :.: .
CCDS14 MAHSPVAVQVPGMQNNIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEE
10 20 30 40 50
180 190 200 210 220
pF1KB0 --DQFKPSDVEIQACFRHEN--IAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMRE
:... . :: . . .. ... ::. : : . ..:: :::.:. :.. ::. :
CCDS14 AEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRA-GPFDE
60 70 80 90 100 110
230 240 250 260 270 280
pF1KB0 FEIIWVTKHVLKGLDFLHSKKVIHHDIKPSNIVFMSTKAV-LVDFGLSVQMTEDVYFPKD
:.: . :..:::::.:::.: ::.::: .:... : :.:::.. :.:. .
CCDS14 FQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNT
120 130 140 150 160 170
290 300 310 320 330 340
pF1KB0 LRGTEIYMSPEVILCRGHSTKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQ
. :: ..:.:::: ....::::.::: : :.. : :: .: . :..: :.
CCDS14 FVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRV----LFLIPKN
180 190 200 210 220 230
350 360 370 380 390 400
pF1KB0 APPLEDIADDCSPGMRELIEASLERNPNHRPRAADLLKHEALNPPREDQPRCQSLDSALL
:: .. : . ...:.:.: :...:. :: : .::::.
CCDS14 NPP--TLVGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELIDRFK
240 250 260 270 280 290
410 420 430 440 450 460
pF1KB0 ERKRLLSRKELELPENIADSSCTGSTEESEMLKRQRSLYIDLGALAGYFNLVRGPPTLEY
CCDS14 RWKAEGHSDDESDSEGSDSESTSRENNTHPEWSFTTVRKKPDPKKVQNGAEQDLVQTLSC
300 310 320 330 340 350
>>CCDS32001.1 STK24 gene_id:8428|Hs108|chr13 (431 aa)
initn: 350 init1: 153 opt: 479 Z-score: 314.5 bits: 67.4 E(32554): 3.4e-11
Smith-Waterman score: 479; 35.6% identity (66.0% similar) in 250 aa overlap (144-386:30-272)
120 130 140 150 160 170
pF1KB0 ITPQNGRYQIDSDVLLIPWKLTYRNIGSDFIPRGAFGKVYLAQDIKTKKRMACKLIPV--
: .:.::.:. . : .:.: .: :.: .
CCDS32 MAHSPVQSGLPGMQNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEE
10 20 30 40 50
180 190 200 210 220
pF1KB0 --DQFKPSDVEIQACFRHEN--IAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMRE
:... . :: . . .. ... ::. : . ..:: :::.:. :: ::. :
CCDS32 AEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEP-GPLDE
60 70 80 90 100 110
230 240 250 260 270 280
pF1KB0 FEIIWVTKHVLKGLDFLHSKKVIHHDIKPSNIVFMSTKAV-LVDFGLSVQMTEDVYFPKD
.: . ...:::::.:::.: ::.::: .:... : :.:::.. :.:. .
CCDS32 TQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNT
120 130 140 150 160 170
290 300 310 320 330 340
pF1KB0 LRGTEIYMSPEVILCRGHSTKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQ
. :: ..:.:::: ....::::.::: : :.. : :: . .: .. :..: :.
CCDS32 FVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELHPMKV----LFLIPKN
180 190 200 210 220 230
350 360 370 380 390 400
pF1KB0 APPLEDIADDCSPGMRELIEASLERNPNHRPRAADLLKHEALNPPREDQPRCQSLDSALL
:: . . : ..:..:: :...:. :: : .::::.
CCDS32 NPP--TLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDRYK
240 250 260 270 280 290
410 420 430 440 450 460
pF1KB0 ERKRLLSRKELELPENIADSSCTGSTEESEMLKRQRSLYIDLGALAGYFNLVRGPPTLEY
CCDS32 RWKAEQSHDDSSSEDSDAETDGQASGGSDSGDWIFTIREKDPKNLENGALQPSDLDRNKM
300 310 320 330 340 350
>>CCDS9488.1 STK24 gene_id:8428|Hs108|chr13 (443 aa)
initn: 350 init1: 153 opt: 479 Z-score: 314.4 bits: 67.4 E(32554): 3.4e-11
Smith-Waterman score: 479; 35.6% identity (66.0% similar) in 250 aa overlap (144-386:42-284)
120 130 140 150 160 170
pF1KB0 ITPQNGRYQIDSDVLLIPWKLTYRNIGSDFIPRGAFGKVYLAQDIKTKKRMACKLIPV--
: .:.::.:. . : .:.: .: :.: .
CCDS94 LNKRRATLPHPGGSTNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEE
20 30 40 50 60 70
180 190 200 210 220
pF1KB0 --DQFKPSDVEIQACFRHEN--IAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMRE
:... . :: . . .. ... ::. : . ..:: :::.:. :: ::. :
CCDS94 AEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEP-GPLDE
80 90 100 110 120 130
230 240 250 260 270 280
pF1KB0 FEIIWVTKHVLKGLDFLHSKKVIHHDIKPSNIVFMSTKAV-LVDFGLSVQMTEDVYFPKD
.: . ...:::::.:::.: ::.::: .:... : :.:::.. :.:. .
CCDS94 TQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNT
140 150 160 170 180 190
290 300 310 320 330 340
pF1KB0 LRGTEIYMSPEVILCRGHSTKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQ
. :: ..:.:::: ....::::.::: : :.. : :: . .: .. :..: :.
CCDS94 FVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELHPMKV----LFLIPKN
200 210 220 230 240
350 360 370 380 390 400
pF1KB0 APPLEDIADDCSPGMRELIEASLERNPNHRPRAADLLKHEALNPPREDQPRCQSLDSALL
:: . . : ..:..:: :...:. :: : .::::.
CCDS94 NPP--TLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDRYK
250 260 270 280 290 300
410 420 430 440 450 460
pF1KB0 ERKRLLSRKELELPENIADSSCTGSTEESEMLKRQRSLYIDLGALAGYFNLVRGPPTLEY
CCDS94 RWKAEQSHDDSSSEDSDAETDGQASGGSDSGDWIFTIREKDPKNLENGALQPSDLDRNKM
310 320 330 340 350 360
467 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 16:47:23 2016 done: Sat Nov 5 16:47:24 2016
Total Scan time: 2.960 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]