Result of FASTA (ccds) for
pF1KB0415
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0415, 468 aa
1>>>pF1KB0415 468 - 468 aa - 468 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9241+/-0.000744; mu= 11.1342+/- 0.045
mean_var=122.9541+/-24.458, 0's: 0 Z-trim(112.7): 54 B-trim: 0 in 0/55
Lambda= 0.115665
statistics sampled from 13370 (13424) to 13370 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.759), E-opt: 0.2 (0.412), width: 16
Scan time: 3.250
The best scores are: opt bits E(32554)
CCDS1067.1 IL6R gene_id:3570|Hs108|chr1 ( 468) 3235 550.7 1.2e-156
CCDS1068.1 IL6R gene_id:3570|Hs108|chr1 ( 365) 2467 422.5 3.7e-118
CCDS72927.1 IL6R gene_id:3570|Hs108|chr1 ( 352) 2230 382.9 2.9e-106
CCDS6567.1 IL11RA gene_id:3590|Hs108|chr9 ( 422) 506 95.3 1.3e-19
CCDS6558.1 CNTFR gene_id:1271|Hs108|chr9 ( 372) 372 72.9 6.4e-13
>>CCDS1067.1 IL6R gene_id:3570|Hs108|chr1 (468 aa)
initn: 3235 init1: 3235 opt: 3235 Z-score: 2925.9 bits: 550.7 E(32554): 1.2e-156
Smith-Waterman score: 3235; 100.0% identity (100.0% similar) in 468 aa overlap (1-468:1-468)
10 20 30 40 50 60
pF1KB0 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 PHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 PHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 GEWSEWSPEAMGTPWTESRSPPAENEVSTPMQALTTNKDDDNILFRDSANATSLPVQDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 GEWSEWSPEAMGTPWTESRSPPAENEVSTPMQALTTNKDDDNILFRDSANATSLPVQDSS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 SVPLPTFLVAGGSLAFGTLLCIAIVLRFKKTWKLRALKEGKTSMHPPYSLGQLVPERPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 SVPLPTFLVAGGSLAFGTLLCIAIVLRFKKTWKLRALKEGKTSMHPPYSLGQLVPERPRP
370 380 390 400 410 420
430 440 450 460
pF1KB0 TPVLVPLISPPVSPSSLGSDNTSSHNRPDARDPRSPYDISNTDYFFPR
::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 TPVLVPLISPPVSPSSLGSDNTSSHNRPDARDPRSPYDISNTDYFFPR
430 440 450 460
>>CCDS1068.1 IL6R gene_id:3570|Hs108|chr1 (365 aa)
initn: 2467 init1: 2467 opt: 2467 Z-score: 2234.9 bits: 422.5 E(32554): 3.7e-118
Smith-Waterman score: 2467; 100.0% identity (100.0% similar) in 355 aa overlap (1-355:1-355)
10 20 30 40 50 60
pF1KB0 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 PHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 PHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 GEWSEWSPEAMGTPWTESRSPPAENEVSTPMQALTTNKDDDNILFRDSANATSLPVQDSS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 GEWSEWSPEAMGTPWTESRSPPAENEVSTPMQALTTNKDDDNILFRDSANATSLPGSRRR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 SVPLPTFLVAGGSLAFGTLLCIAIVLRFKKTWKLRALKEGKTSMHPPYSLGQLVPERPRP
CCDS10 GSCGL
>>CCDS72927.1 IL6R gene_id:3570|Hs108|chr1 (352 aa)
initn: 2230 init1: 2230 opt: 2230 Z-score: 2021.3 bits: 382.9 E(32554): 2.9e-106
Smith-Waterman score: 2230; 99.1% identity (99.4% similar) in 321 aa overlap (1-321:1-321)
10 20 30 40 50 60
pF1KB0 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 PHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 PHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 GEWSEWSPEAMGTPWTESRSPPAENEVSTPMQALTTNKDDDNILFRDSANATSLPVQDSS
::::::::::::::::. ::
CCDS72 GEWSEWSPEAMGTPWTDRLSPRCPGWSTAVQSQLTATSASWVQAILPPQPPK
310 320 330 340 350
>>CCDS6567.1 IL11RA gene_id:3590|Hs108|chr9 (422 aa)
initn: 354 init1: 139 opt: 506 Z-score: 465.4 bits: 95.3 E(32554): 1.3e-19
Smith-Waterman score: 506; 29.9% identity (53.8% similar) in 435 aa overlap (2-420:1-417)
10 20 30 40 50
pF1KB0 MLAVGCALLAALLAAPGAAL--APRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATV
.. .:. :. .:.: ..:: : :: :: . :: :: : :::: : :
CCDS65 MSSSCSGLSRVLVAVATALVSASSPCPQAWGPPGVQYGQPGRSVKLCCPGVTAGD--PV
10 20 30 40 50
60 70 80 90 100 110
pF1KB0 HWVLR--KPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRA-GRPAGTVHLLVDVPPE
: .: .: . :. .:.:..:.: ... : :.: : : .::: : . ::
CCDS65 SW-FRDGEPKLLQGPD--SGLGHELVLAQADSTDEGTYICQTLDGALGGTVTLQLGYPPA
60 70 80 90 100 110
120 130 140 150 160
pF1KB0 EPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQE--------PCQY
.: .:: . . : : :.: . .: :. . :: .. . : :. ::
CCDS65 RPVVSC-QAADYENFSCTWSPSQISGLPTRYLTSYRK-KTVLGADSQRRSPSTGPWPCPQ
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB0 SQESQKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAV
. . : . : :.. : .. .. .:.. .. . .::.:::: .. : .:
CCDS65 DPLGAA-RCVVHGAEFWSQYRI-NVTEVNPLGAS-TRLLDVSLQSILRPDPPQGLRVESV
180 190 200 210 220
230 240 250 260 270 280
pF1KB0 ARNPRWLSVTWQDPHSWNSS-FYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGL
:: : ..: : :: . . :.:.:.:: . ...: :.. :: :: .::
CCDS65 PGYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEE--VITDAVAGL
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB0 RHVVQLRAQEEFGQGEWSEWSPEAMGTPWTES--RSPPAENEVSTPMQALTTNKDDDNIL
:.:.. :.. . : :: ::::: ::: : . . :: ... : : . . :.
CCDS65 PHAVRVSARDFLDAGTWSTWSPEAWGTPSTGTIPKEIPAWGQLHT--QPEVEPQVDSPAP
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB0 FRDSANATSLPVQDSSSVPLPTFLVAGGSLAFGTLLCIAIVLRFKKTWKLRALKEGKTSM
: : . .. .:: . :.. : :.: :. :..: . : :: . :: .
CCDS65 PRPSLQPHPRLLDHRDSVEQVAVLASLGILSFLGLVAGALALGL---W-LRLRRGGKDGS
350 360 370 380 390 400
410 420 430 440 450 460
pF1KB0 HPPYSLGQLVPERPRPTPVLVPLISPPVSPSSLGSDNTSSHNRPDARDPRSPYDISNTDY
: :....: ::
CCDS65 PKPGFLASVIPVDRRPGAPNL
410 420
>>CCDS6558.1 CNTFR gene_id:1271|Hs108|chr9 (372 aa)
initn: 272 init1: 145 opt: 372 Z-score: 345.4 bits: 72.9 E(32554): 6.4e-13
Smith-Waterman score: 420; 29.9% identity (55.2% similar) in 388 aa overlap (6-386:10-358)
10 20 30 40 50
pF1KB0 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNA
::.:: :: ... : :. : ::. . : :..::: : :. : :
CCDS65 MAAPVPWACCAVLA---AAAAVVYAQRHSP-QEAPHVQYERL-GSDVTLPC-GTANWD-A
10 20 30 40 50
60 70 80 90 100 110
pF1KB0 TVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR--AGRPAGTVHLLVDVPP
.: : : .. :. : .:.:....: :: :.:.. . . : : : .::
CCDS65 AVTW--RVNGTDLAPDLLNG--SQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPP
60 70 80 90 100
120 130 140 150 160 170
pF1KB0 EEPQLSCFRKSPLSNVVCEWG---PRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQES
.:: ::: .. .. : : : :. . .:: :.. :. .. .
CCDS65 REPVLSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIMV---------CE-KDPA
110 120 130 140 150
180 190 200 210 220 230
pF1KB0 QKFSCQLAVPEGDSSF-YIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARN
: :.. . :.. : ::. :....: . . . ::. :..:::: :... : :
CCDS65 LKNRCHIRYMHLFSTIKYKVSISVSNALGHN-ATAITFDEFTIVKPDPPENVVARPVPSN
160 170 180 190 200 210
240 250 260 270 280
pF1KB0 PRWLSVTWQDPHSW-NSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHV
:: : :::: : .: . . :.: :::: . ..: : .: ::..: ...
CCDS65 PRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELSDGTAH-TITDAYAGKEYI
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB0 VQLRAQEEFGQGEWSEWSPEAMGTPWTESRSPPAENEVSTPMQALTTNKDDDNILFRDSA
.:. :... : ::.:: : .::::: : ...: :: :. ..
CCDS65 IQVAAKDNE-IGTWSDWSVAAHATPWTE--EP---RHLTTEAQAAETT----------TS
280 290 300 310 320
350 360 370 380 390 400
pF1KB0 NATSLPVQDSSSVPLPTFLVAGGSLAFGTLLCIAIVLRFKKTWKLRALKEGKTSMHPPYS
...:: .... : : .::. . :. . :.:
CCDS65 TTSSLAPPPTTKICDPGELGSGGGPSAPFLVSVPITLALAAAAATASSLLI
330 340 350 360 370
410 420 430 440 450 460
pF1KB0 LGQLVPERPRPTPVLVPLISPPVSPSSLGSDNTSSHNRPDARDPRSPYDISNTDYFFPR
468 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 16:48:01 2016 done: Sat Nov 5 16:48:02 2016
Total Scan time: 3.250 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]