FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0415, 468 aa 1>>>pF1KB0415 468 - 468 aa - 468 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.8114+/-0.000326; mu= 11.9924+/- 0.020 mean_var=137.4255+/-27.817, 0's: 0 Z-trim(119.8): 100 B-trim: 713 in 1/60 Lambda= 0.109406 statistics sampled from 34132 (34281) to 34132 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.751), E-opt: 0.2 (0.402), width: 16 Scan time: 9.880 The best scores are: opt bits E(85289) NP_000556 (OMIM: 147880,614689,614752) interleukin ( 468) 3235 522.0 1.4e-147 XP_016856689 (OMIM: 147880,614689,614752) PREDICTE ( 501) 2471 401.4 2.9e-111 NP_852004 (OMIM: 147880,614689,614752) interleukin ( 365) 2467 400.7 3.5e-111 NP_001193795 (OMIM: 147880,614689,614752) interleu ( 352) 2230 363.3 6.2e-100 XP_006711362 (OMIM: 147880,614689,614752) PREDICTE ( 381) 2218 361.4 2.5e-99 XP_006711361 (OMIM: 147880,614689,614752) PREDICTE ( 484) 2219 361.6 2.6e-99 XP_016856688 (OMIM: 147880,614689,614752) PREDICTE ( 517) 2218 361.5 3.1e-99 XP_005245197 (OMIM: 147880,614689,614752) PREDICTE ( 338) 1866 305.8 1.2e-82 XP_005245196 (OMIM: 147880,614689,614752) PREDICTE ( 360) 1866 305.8 1.3e-82 XP_016856690 (OMIM: 147880,614689,614752) PREDICTE ( 371) 1866 305.8 1.3e-82 NP_001136256 (OMIM: 600939,614188) interleukin-11 ( 422) 506 91.2 5.9e-18 XP_016869752 (OMIM: 118946) PREDICTED: ciliary neu ( 372) 372 70.0 1.2e-11 NP_001193940 (OMIM: 118946) ciliary neurotrophic f ( 372) 372 70.0 1.2e-11 NP_001833 (OMIM: 118946) ciliary neurotrophic fact ( 372) 372 70.0 1.2e-11 NP_671693 (OMIM: 118946) ciliary neurotrophic fact ( 372) 372 70.0 1.2e-11 XP_016869754 (OMIM: 118946) PREDICTED: ciliary neu ( 372) 372 70.0 1.2e-11 XP_016869753 (OMIM: 118946) PREDICTED: ciliary neu ( 372) 372 70.0 1.2e-11 XP_016869750 (OMIM: 118946) PREDICTED: ciliary neu ( 439) 372 70.1 1.4e-11 XP_016869749 (OMIM: 118946) PREDICTED: ciliary neu ( 439) 372 70.1 1.4e-11 XP_016869751 (OMIM: 118946) PREDICTED: ciliary neu ( 439) 372 70.1 1.4e-11 XP_011526726 (OMIM: 272430,604237) PREDICTED: cyto ( 404) 287 56.6 1.4e-07 XP_011526725 (OMIM: 272430,604237) PREDICTED: cyto ( 419) 287 56.6 1.5e-07 NP_004741 (OMIM: 272430,604237) cytokine receptor- ( 422) 287 56.6 1.5e-07 XP_011526724 (OMIM: 272430,604237) PREDICTED: cyto ( 423) 287 56.6 1.5e-07 NP_786943 (OMIM: 600694) interleukin-6 receptor su ( 329) 218 45.7 0.00024 NP_001177910 (OMIM: 600694) interleukin-6 receptor ( 857) 222 46.6 0.00031 NP_002175 (OMIM: 600694) interleukin-6 receptor su ( 918) 222 46.7 0.00033 XP_011525921 (OMIM: 605816) PREDICTED: interleukin ( 229) 212 44.6 0.00035 NP_005746 (OMIM: 605816) interleukin-27 subunit be ( 229) 212 44.6 0.00035 NP_001191247 (OMIM: 176761,615554,615555) prolacti ( 268) 209 44.2 0.00054 NP_001191246 (OMIM: 176761,615554,615555) prolacti ( 288) 209 44.2 0.00057 XP_016865135 (OMIM: 176761,615554,615555) PREDICTE ( 309) 209 44.2 0.0006 NP_001191244 (OMIM: 176761,615554,615555) prolacti ( 349) 209 44.3 0.00066 NP_001191245 (OMIM: 176761,615554,615555) prolacti ( 376) 209 44.3 0.0007 NP_000940 (OMIM: 176761,615554,615555) prolactin r ( 622) 209 44.5 0.001 XP_011512370 (OMIM: 176761,615554,615555) PREDICTE ( 622) 209 44.5 0.001 XP_006714547 (OMIM: 176761,615554,615555) PREDICTE ( 622) 209 44.5 0.001 XP_011512371 (OMIM: 176761,615554,615555) PREDICTE ( 622) 209 44.5 0.001 XP_016856693 (OMIM: 601642) PREDICTED: interleukin ( 498) 202 43.3 0.0018 NP_001245145 (OMIM: 601642) interleukin-12 recepto ( 635) 202 43.4 0.0022 NP_001306162 (OMIM: 601642) interleukin-12 recepto ( 659) 202 43.4 0.0023 XP_016856692 (OMIM: 601642) PREDICTED: interleukin ( 659) 202 43.4 0.0023 NP_001245143 (OMIM: 601642) interleukin-12 recepto ( 659) 202 43.4 0.0023 XP_016856691 (OMIM: 601642) PREDICTED: interleukin ( 700) 202 43.4 0.0024 XP_006710680 (OMIM: 601642) PREDICTED: interleukin ( 776) 202 43.5 0.0026 NP_001245144 (OMIM: 601642) interleukin-12 recepto ( 776) 202 43.5 0.0026 XP_011539686 (OMIM: 601642) PREDICTED: interleukin ( 809) 202 43.5 0.0027 XP_005270884 (OMIM: 601642) PREDICTED: interleukin ( 862) 202 43.5 0.0028 XP_005270882 (OMIM: 601642) PREDICTED: interleukin ( 862) 202 43.5 0.0028 XP_011539685 (OMIM: 601642) PREDICTED: interleukin ( 862) 202 43.5 0.0028 >>NP_000556 (OMIM: 147880,614689,614752) interleukin-6 r (468 aa) initn: 3235 init1: 3235 opt: 3235 Z-score: 2770.7 bits: 522.0 E(85289): 1.4e-147 Smith-Waterman score: 3235; 100.0% identity (100.0% similar) in 468 aa overlap (1-468:1-468) 10 20 30 40 50 60 pF1KB0 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 PHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 GEWSEWSPEAMGTPWTESRSPPAENEVSTPMQALTTNKDDDNILFRDSANATSLPVQDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GEWSEWSPEAMGTPWTESRSPPAENEVSTPMQALTTNKDDDNILFRDSANATSLPVQDSS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 SVPLPTFLVAGGSLAFGTLLCIAIVLRFKKTWKLRALKEGKTSMHPPYSLGQLVPERPRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SVPLPTFLVAGGSLAFGTLLCIAIVLRFKKTWKLRALKEGKTSMHPPYSLGQLVPERPRP 370 380 390 400 410 420 430 440 450 460 pF1KB0 TPVLVPLISPPVSPSSLGSDNTSSHNRPDARDPRSPYDISNTDYFFPR :::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TPVLVPLISPPVSPSSLGSDNTSSHNRPDARDPRSPYDISNTDYFFPR 430 440 450 460 >>XP_016856689 (OMIM: 147880,614689,614752) PREDICTED: i (501 aa) initn: 2471 init1: 2471 opt: 2471 Z-score: 2118.6 bits: 401.4 E(85289): 2.9e-111 Smith-Waterman score: 3155; 93.2% identity (93.4% similar) in 501 aa overlap (1-468:1-501) 10 20 30 40 50 60 pF1KB0 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 PHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ 250 260 270 280 290 300 310 320 330 340 350 pF1KB0 GEWSEWSPEAMGTPWTESRSPPAENEVSTPMQALTTNKDDDNILFRDSANATSLP----- ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEWSEWSPEAMGTPWTESRSPPAENEVSTPMQALTTNKDDDNILFRDSANATSLPGTAIK 310 320 330 340 350 360 360 370 380 pF1KB0 ----------------------------VQDSSSVPLPTFLVAGGSLAFGTLLCIAIVLR .::::::::::::::::::::::::::::::: XP_016 EVPKAFRLLYPLCALWEQVECHQKSHSEMQDSSSVPLPTFLVAGGSLAFGTLLCIAIVLR 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB0 FKKTWKLRALKEGKTSMHPPYSLGQLVPERPRPTPVLVPLISPPVSPSSLGSDNTSSHNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKKTWKLRALKEGKTSMHPPYSLGQLVPERPRPTPVLVPLISPPVSPSSLGSDNTSSHNR 430 440 450 460 470 480 450 460 pF1KB0 PDARDPRSPYDISNTDYFFPR ::::::::::::::::::::: XP_016 PDARDPRSPYDISNTDYFFPR 490 500 >>NP_852004 (OMIM: 147880,614689,614752) interleukin-6 r (365 aa) initn: 2467 init1: 2467 opt: 2467 Z-score: 2117.0 bits: 400.7 E(85289): 3.5e-111 Smith-Waterman score: 2467; 100.0% identity (100.0% similar) in 355 aa overlap (1-355:1-355) 10 20 30 40 50 60 pF1KB0 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_852 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_852 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_852 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_852 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 PHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_852 PHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 GEWSEWSPEAMGTPWTESRSPPAENEVSTPMQALTTNKDDDNILFRDSANATSLPVQDSS ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_852 GEWSEWSPEAMGTPWTESRSPPAENEVSTPMQALTTNKDDDNILFRDSANATSLPGSRRR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 SVPLPTFLVAGGSLAFGTLLCIAIVLRFKKTWKLRALKEGKTSMHPPYSLGQLVPERPRP NP_852 GSCGL >>NP_001193795 (OMIM: 147880,614689,614752) interleukin- (352 aa) initn: 2230 init1: 2230 opt: 2230 Z-score: 1915.1 bits: 363.3 E(85289): 6.2e-100 Smith-Waterman score: 2230; 99.1% identity (99.4% similar) in 321 aa overlap (1-321:1-321) 10 20 30 40 50 60 pF1KB0 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 PHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 GEWSEWSPEAMGTPWTESRSPPAENEVSTPMQALTTNKDDDNILFRDSANATSLPVQDSS ::::::::::::::::. :: NP_001 GEWSEWSPEAMGTPWTDRLSPRCPGWSTAVQSQLTATSASWVQAILPPQPPK 310 320 330 340 350 >>XP_006711362 (OMIM: 147880,614689,614752) PREDICTED: i (381 aa) initn: 2453 init1: 2217 opt: 2218 Z-score: 1904.4 bits: 361.4 E(85289): 2.5e-99 Smith-Waterman score: 2425; 95.7% identity (95.7% similar) in 371 aa overlap (1-355:1-371) 10 20 30 40 50 60 pF1KB0 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 PHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ 250 260 270 280 290 300 310 320 330 340 pF1KB0 GEWSEWSPEAMGTPWT----------------ESRSPPAENEVSTPMQALTTNKDDDNIL :::::::::::::::: :::::::::::::::::::::::::::: XP_006 GEWSEWSPEAMGTPWTGFSPQTIPGGIWDPAGESRSPPAENEVSTPMQALTTNKDDDNIL 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB0 FRDSANATSLPVQDSSSVPLPTFLVAGGSLAFGTLLCIAIVLRFKKTWKLRALKEGKTSM ::::::::::: XP_006 FRDSANATSLPGSRRRGSCGL 370 380 >>XP_006711361 (OMIM: 147880,614689,614752) PREDICTED: i (484 aa) initn: 3221 init1: 2217 opt: 2219 Z-score: 1903.8 bits: 361.6 E(85289): 2.6e-99 Smith-Waterman score: 3193; 96.7% identity (96.7% similar) in 484 aa overlap (1-468:1-484) 10 20 30 40 50 60 pF1KB0 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 PHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ 250 260 270 280 290 300 310 320 330 340 pF1KB0 GEWSEWSPEAMGTPWT----------------ESRSPPAENEVSTPMQALTTNKDDDNIL :::::::::::::::: :::::::::::::::::::::::::::: XP_006 GEWSEWSPEAMGTPWTGFSPQTIPGGIWDPAGESRSPPAENEVSTPMQALTTNKDDDNIL 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB0 FRDSANATSLPVQDSSSVPLPTFLVAGGSLAFGTLLCIAIVLRFKKTWKLRALKEGKTSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FRDSANATSLPVQDSSSVPLPTFLVAGGSLAFGTLLCIAIVLRFKKTWKLRALKEGKTSM 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB0 HPPYSLGQLVPERPRPTPVLVPLISPPVSPSSLGSDNTSSHNRPDARDPRSPYDISNTDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HPPYSLGQLVPERPRPTPVLVPLISPPVSPSSLGSDNTSSHNRPDARDPRSPYDISNTDY 430 440 450 460 470 480 pF1KB0 FFPR :::: XP_006 FFPR >>XP_016856688 (OMIM: 147880,614689,614752) PREDICTED: i (517 aa) initn: 2967 init1: 2217 opt: 2218 Z-score: 1902.6 bits: 361.5 E(85289): 3.1e-99 Smith-Waterman score: 2986; 90.0% identity (90.2% similar) in 500 aa overlap (1-451:1-500) 10 20 30 40 50 60 pF1KB0 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 PHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ 250 260 270 280 290 300 310 320 330 340 pF1KB0 GEWSEWSPEAMGTPWT----------------ESRSPPAENEVSTPMQALTTNKDDDNIL :::::::::::::::: :::::::::::::::::::::::::::: XP_016 GEWSEWSPEAMGTPWTGFSPQTIPGGIWDPAGESRSPPAENEVSTPMQALTTNKDDDNIL 310 320 330 340 350 360 350 360 370 pF1KB0 FRDSANATSLP---------------------------------VQDSSSVPLPTFLVAG ::::::::::: .::::::::::::::: XP_016 FRDSANATSLPGTAIKEVPKAFRLLYPLCALWEQVECHQKSHSEMQDSSSVPLPTFLVAG 370 380 390 400 410 420 380 390 400 410 420 430 pF1KB0 GSLAFGTLLCIAIVLRFKKTWKLRALKEGKTSMHPPYSLGQLVPERPRPTPVLVPLISPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLAFGTLLCIAIVLRFKKTWKLRALKEGKTSMHPPYSLGQLVPERPRPTPVLVPLISPP 430 440 450 460 470 480 440 450 460 pF1KB0 VSPSSLGSDNTSSHNRPDARDPRSPYDISNTDYFFPR :::::::::::::::::::: XP_016 VSPSSLGSDNTSSHNRPDARDPRSPYDISNTDYFFPR 490 500 510 >>XP_005245197 (OMIM: 147880,614689,614752) PREDICTED: i (338 aa) initn: 1886 init1: 1863 opt: 1866 Z-score: 1604.8 bits: 305.8 E(85289): 1.2e-82 Smith-Waterman score: 1866; 97.1% identity (98.2% similar) in 280 aa overlap (1-277:1-280) 10 20 30 40 50 60 pF1KB0 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD 190 200 210 220 230 240 250 260 270 280 290 pF1KB0 PHSWNSSFYRLRFELRYRAERSKTFTTWM---VKDLQHHCVIHDAWSGLRHVVQLRAQEE ::::::::::::::::::::::::::::: : .:. .: XP_005 PHSWNSSFYRLRFELRYRAERSKTFTTWMNPGVLQLRTRCPPPCRHLLLIKTMIIFSSEI 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB0 FGQGEWSEWSPEAMGTPWTESRSPPAENEVSTPMQALTTNKDDDNILFRDSANATSLPVQ XP_005 LQMRQASQCKILLQYHCPHSWLLEGAWPSERSSALPLF 310 320 330 >>XP_005245196 (OMIM: 147880,614689,614752) PREDICTED: i (360 aa) initn: 1863 init1: 1863 opt: 1866 Z-score: 1604.4 bits: 305.8 E(85289): 1.3e-82 Smith-Waterman score: 1866; 97.1% identity (98.2% similar) in 280 aa overlap (1-277:1-280) 10 20 30 40 50 60 pF1KB0 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD 190 200 210 220 230 240 250 260 270 280 290 pF1KB0 PHSWNSSFYRLRFELRYRAERSKTFTTWM---VKDLQHHCVIHDAWSGLRHVVQLRAQEE ::::::::::::::::::::::::::::: : .:. .: XP_005 PHSWNSSFYRLRFELRYRAERSKTFTTWMNPGVLQLRTRCPPPCRHLLLIKTMIIFSSEI 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB0 FGQGEWSEWSPEAMGTPWTESRSPPAENEVSTPMQALTTNKDDDNILFRDSANATSLPVQ XP_005 LQMRQASQVQEDVEAAGSEGRQDKHASAVLFGAAGPGEASTHPSACSSHLPTGVPQQPGV 310 320 330 340 350 360 >>XP_016856690 (OMIM: 147880,614689,614752) PREDICTED: i (371 aa) initn: 1886 init1: 1863 opt: 1866 Z-score: 1604.3 bits: 305.8 E(85289): 1.3e-82 Smith-Waterman score: 1866; 97.1% identity (98.2% similar) in 280 aa overlap (1-277:1-280) 10 20 30 40 50 60 pF1KB0 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD 190 200 210 220 230 240 250 260 270 280 290 pF1KB0 PHSWNSSFYRLRFELRYRAERSKTFTTWM---VKDLQHHCVIHDAWSGLRHVVQLRAQEE ::::::::::::::::::::::::::::: : .:. .: XP_016 PHSWNSSFYRLRFELRYRAERSKTFTTWMNPGVLQLRTRCPPPCRHLLLIKTMIIFSSEI 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB0 FGQGEWSEWSPEAMGTPWTESRSPPAENEVSTPMQALTTNKDDDNILFRDSANATSLPVQ XP_016 LQMRQASQELPSRRSPKPSVCCTLFVPCGSRWNVTRKATLKCKILLQYHCPHSWLLEGAW 310 320 330 340 350 360 468 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:48:02 2016 done: Sat Nov 5 16:48:03 2016 Total Scan time: 9.880 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]