FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0434, 866 aa 1>>>pF1KB0434 866 - 866 aa - 866 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.8847+/-0.000526; mu= 3.6416+/- 0.033 mean_var=192.0819+/-38.334, 0's: 0 Z-trim(113.1): 3 B-trim: 0 in 0/55 Lambda= 0.092540 statistics sampled from 22253 (22255) to 22253 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.586), E-opt: 0.2 (0.261), width: 16 Scan time: 12.190 The best scores are: opt bits E(85289) NP_476516 (OMIM: 608000) N-alpha-acetyltransferase ( 866) 5754 782.0 0 XP_005263293 (OMIM: 608000) PREDICTED: N-alpha-ace ( 865) 5737 779.7 0 >>NP_476516 (OMIM: 608000) N-alpha-acetyltransferase 15, (866 aa) initn: 5754 init1: 5754 opt: 5754 Z-score: 4166.2 bits: 782.0 E(85289): 0 Smith-Waterman score: 5754; 100.0% identity (100.0% similar) in 866 aa overlap (1-866:1-866) 10 20 30 40 50 60 pF1KB0 MPAVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 MPAVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 KKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 KKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 SLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 SLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 SPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 SPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 EDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLKIYEEAWTKYPRGLVPRRLPLNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 EDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLKIYEEAWTKYPRGLVPRRLPLNF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 LSGEKFKECLDKFLRMNFSKGCPPVFNTLRSLYKDKEKVAIIEELVVGYETSLKSCRLFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 LSGEKFKECLDKFLRMNFSKGCPPVFNTLRSLYKDKEKVAIIEELVVGYETSLKSCRLFN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 PNDDGKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 PNDDGKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 AGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTREGTSAVENLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 AGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTREGTSAVENLN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 EMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 EMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 LLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 LLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 RAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEEAIKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 RAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEEAIKF 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 LTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWLHECMIRLFNTAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 LTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWLHECMIRLFNTAV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 CESKDLSDTVRTVLKQEMNRLFGATNPKNFNETFLKRNSDSLPHRLSAAKMVYYLDPSSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 CESKDLSDTVRTVLKQEMNRLFGATNPKNFNETFLKRNSDSLPHRLSAAKMVYYLDPSSQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 KRAIELATTLDESLTNRNLQTCMEVLEALYDGSLGDCKEAAEIYRANCHKLFPYALAFMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 KRAIELATTLDESLTNRNLQTCMEVLEALYDGSLGDCKEAAEIYRANCHKLFPYALAFMP 790 800 810 820 830 840 850 860 pF1KB0 PGYEEDMKITVNGDSSAEAEELANEI :::::::::::::::::::::::::: NP_476 PGYEEDMKITVNGDSSAEAEELANEI 850 860 >>XP_005263293 (OMIM: 608000) PREDICTED: N-alpha-acetylt (865 aa) initn: 4793 init1: 4793 opt: 5737 Z-score: 4153.9 bits: 779.7 E(85289): 0 Smith-Waterman score: 5737; 99.9% identity (99.9% similar) in 866 aa overlap (1-866:1-865) 10 20 30 40 50 60 pF1KB0 MPAVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MPAVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 KKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 SLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 SPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 EDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLKIYEEAWTKYPRGLVPRRLPLNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLKIYEEAWTKYPRGLVPRRLPLNF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 LSGEKFKECLDKFLRMNFSKGCPPVFNTLRSLYKDKEKVAIIEELVVGYETSLKSCRLFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSGEKFKECLDKFLRMNFSKGCPPVFNTLRSLYKDKEKVAIIEELVVGYETSLKSCRLFN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 PNDDGKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PNDDGKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 AGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTREGTSAVENLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTREGTSAVENLN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 EMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 LLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 RAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEEAIKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEEAIKF 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 LTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWLHECMIRLFNTAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_005 LTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWLHECMIRLFNT-V 670 680 690 700 710 730 740 750 760 770 780 pF1KB0 CESKDLSDTVRTVLKQEMNRLFGATNPKNFNETFLKRNSDSLPHRLSAAKMVYYLDPSSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CESKDLSDTVRTVLKQEMNRLFGATNPKNFNETFLKRNSDSLPHRLSAAKMVYYLDPSSQ 720 730 740 750 760 770 790 800 810 820 830 840 pF1KB0 KRAIELATTLDESLTNRNLQTCMEVLEALYDGSLGDCKEAAEIYRANCHKLFPYALAFMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KRAIELATTLDESLTNRNLQTCMEVLEALYDGSLGDCKEAAEIYRANCHKLFPYALAFMP 780 790 800 810 820 830 850 860 pF1KB0 PGYEEDMKITVNGDSSAEAEELANEI :::::::::::::::::::::::::: XP_005 PGYEEDMKITVNGDSSAEAEELANEI 840 850 860 866 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:51:53 2016 done: Sat Nov 5 18:51:55 2016 Total Scan time: 12.190 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]